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Schizophrenia

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Articles published in
Neuropsychopharmacology
    November 2024
  1. ZHANG W, Wang L, Wu X, Yao L, et al
    Improved patient identification by incorporating symptom severity in deep learning using neuroanatomic images in first episode schizophrenia.
    Neuropsychopharmacology. 2024 Nov 6. doi: 10.1038/s41386-024-02021.
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    September 2024
  2. BRAKATSELOS C, Polissidis A, Ntoulas G, Asprogerakas MZ, et al
    Multi-level therapeutic actions of cannabidiol in ketamine-induced schizophrenia psychopathology in male rats.
    Neuropsychopharmacology. 2024 Sep 6. doi: 10.1038/s41386-024-01977.
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    August 2024
  3. SLIFSTEIN M, Qu W, Gil R, Weinstein JJ, et al
    Kappa opioid receptor availability predicts severity of anhedonia in schizophrenia.
    Neuropsychopharmacology. 2024 Aug 31. doi: 10.1038/s41386-024-01975.
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    July 2024
  4. ABRAM SV, Hua JPY
    Pons connectivity correlates with neurophysiological and clinical signatures of predictive coding in psychosis.
    Neuropsychopharmacology. 2024 Jul 22. doi: 10.1038/s41386-024-01919.
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  5. SMUCNY J, Carter CS
    Is treatment-resistant schizophrenia a neuroimmune condition? Meta-analytic evidence from magnetic resonance spectroscopy.
    Neuropsychopharmacology. 2024 Jul 18. doi: 10.1038/s41386-024-01932.
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    June 2024
  6. JOHNSON EC, Austin-Zimmerman I, Thorpe HHA, Levey DF, et al
    Cross-ancestry genetic investigation of schizophrenia, cannabis use disorder, and tobacco smoking.
    Neuropsychopharmacology. 2024 Jun 21. doi: 10.1038/s41386-024-01886.
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  7. CHENOWETH MJ
    Cracking the chicken and egg problem of schizophrenia and substance use: Genetic interplay between schizophrenia, cannabis use disorder, and tobacco smoking.
    Neuropsychopharmacology. 2024 Jun 11. doi: 10.1038/s41386-024-01898.
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  8. KOCH E, Kampe A, Alver M, Siguretharson S, et al
    Polygenic liability for antipsychotic dosage and polypharmacy - a real-world registry and biobank study.
    Neuropsychopharmacology. 2024;49:1113-1119.
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    May 2024
  9. PISANU C, Congiu D, Meloni A, Paribello P, et al
    Dissecting the genetic overlap between severe mental disorders and markers of cellular aging: Identification of pleiotropic genes and druggable targets.
    Neuropsychopharmacology. 2024;49:1033-1041.
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    April 2024
  10. LIVINGSTON NR, Kiemes A, Devenyi GA, Knight S, et al
    Effects of diazepam on hippocampal blood flow in people at clinical high risk for psychosis.
    Neuropsychopharmacology. 2024 Apr 24. doi: 10.1038/s41386-024-01864.
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    March 2024
  11. SCHOONOVER KE, Dienel SJ, Holly Bazmi H, Enwright JF 3rd, et al
    Altered excitatory and inhibitory ionotropic receptor subunit expression in the cortical visuospatial working memory network in schizophrenia.
    Neuropsychopharmacology. 2024 Mar 28. doi: 10.1038/s41386-024-01854.
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  12. HUANG AS, Kang K, Vandekar S, Rogers BP, et al
    Lifespan development of thalamic nuclei and characterizing thalamic nuclei abnormalities in schizophrenia using normative modeling.
    Neuropsychopharmacology. 2024 Mar 13. doi: 10.1038/s41386-024-01837.
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  13. SEITZ-HOLLAND J, Aleman-Gomez Y, Cho KIK, Pasternak O, et al
    Matrix metalloproteinase 9 (MMP-9) activity, hippocampal extracellular free water, and cognitive deficits are associated with each other in early phase psychosis.
    Neuropsychopharmacology. 2024 Mar 2. doi: 10.1038/s41386-024-01814.
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    February 2024
  14. CABRERA-MENDOZA B, Aydin N, Fries GR, Docherty AR, et al
    Estimating the direct effects of the genetic liabilities to bipolar disorder, schizophrenia, and behavioral traits on suicide attempt using a multivariable Mendelian randomization approach.
    Neuropsychopharmacology. 2024 Feb 23. doi: 10.1038/s41386-024-01833.
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  15. TRUONG TTT, Liu ZSJ, Panizzutti B, Kim JH, et al
    Network-based drug repurposing for schizophrenia.
    Neuropsychopharmacology. 2024 Feb 6. doi: 10.1038/s41386-024-01805.
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    January 2024
  16. PAUL SM, Potter WZ
    Finding new and better treatments for psychiatric disorders.
    Neuropsychopharmacology. 2024;49:3-9.
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  17. HANSON JE, Yuan H, Perszyk RE, Banke TG, et al
    Therapeutic potential of N-methyl-D-aspartate receptor modulators in psychiatry.
    Neuropsychopharmacology. 2024;49:51-66.
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    December 2023
  18. ARIME Y, Saitoh Y, Ishikawa M, Kamiyoshihara C, et al
    Activation of prefrontal parvalbumin interneurons ameliorates working memory deficit even under clinically comparable antipsychotic treatment in a mouse model of schizophrenia.
    Neuropsychopharmacology. 2023 Dec 4. doi: 10.1038/s41386-023-01769.
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    October 2023
  19. WANG DM, Chen DC, Xiu MH, Wang L, et al
    A double-blind, randomized controlled study of the effects of celecoxib on clinical symptoms and cognitive impairment in patients with drug-naive first episode schizophrenia: pharmacogenetic impact of cyclooxygenase-2 functional polymorphisms.
    Neuropsychopharmacology. 2023 Oct 30. doi: 10.1038/s41386-023-01760.
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  20. ROESKE MJ, McHugo M, Rogers B, Armstrong K, et al
    Modulation of hippocampal activity in schizophrenia with levetiracetam: a randomized, double-blind, cross-over, placebo-controlled trial.
    Neuropsychopharmacology. 2023 Oct 13. doi: 10.1038/s41386-023-01730.
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    September 2023
  21. FAN L, Liang L, Wang Y, Ma X, et al
    Glutamatergic basis of antipsychotic response in first-episode psychosis: a dual voxel study of the anterior cingulate cortex.
    Neuropsychopharmacology. 2023 Sep 26. doi: 10.1038/s41386-023-01741.
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  22. ZHOU DY, Su X, Wu Y, Yang Y, et al
    Decreased CNNM2 expression in prefrontal cortex affects sensorimotor gating function, cognition, dendritic spine morphogenesis and risk of schizophrenia.
    Neuropsychopharmacology. 2023 Sep 15. doi: 10.1038/s41386-023-01732.
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  23. RABIN RA, Palaniyappan L
    Brain health in ethnically minority youth at risk for psychosis.
    Neuropsychopharmacology. 2023 Sep 4. doi: 10.1038/s41386-023-01719.
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    August 2023
  24. WEICKERT TW, Weickert CS
    A path to novel, effective treatments for schizophrenia.
    Neuropsychopharmacology. 2023 Aug 14. doi: 10.1038/s41386-023-01705.
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  25. TRANTER MM, Aggarwal S, Young JW, Dillon DG, et al
    Reinforcement learning deficits exhibited by postnatal PCP-treated rats enable deep neural network classification.
    Neuropsychopharmacology. 2023;48:1377-1385.
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    July 2023
  26. JIANG H, Chen P, Sun Z, Liang C, et al
    Assisting schizophrenia diagnosis using clinical electroencephalography and interpretable graph neural networks: a real-world and cross-site study.
    Neuropsychopharmacology. 2023 Jul 25. doi: 10.1038/s41386-023-01658.
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  27. KU BS, Collins M, Anglin DM, Diomino AM, et al
    Associations between childhood ethnoracial minority density, cortical thickness, and social engagement among minority youth at clinical high-risk for psychosis.
    Neuropsychopharmacology. 2023 Jul 12. doi: 10.1038/s41386-023-01649.
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    April 2023
  28. HARE SM, Adhikari BM, Mo C, Chen S, et al
    Tryptophan challenge in individuals with schizophrenia and healthy controls: acute effects on circulating kynurenine and kynurenic acid, cognition and cerebral blood flow.
    Neuropsychopharmacology. 2023 Apr 28. doi: 10.1038/s41386-023-01587.
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  29. DUNCAN L, Shen H, Schulmann A, Li T, et al
    Polygenic scores for psychiatric disorders in a diverse postmortem brain tissue cohort.
    Neuropsychopharmacology. 2023;48:764-772.
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    March 2023
  30. O'DONNELL P, Dong C, Murthy V, Asgharnejad M, et al
    The D-amino acid oxidase inhibitor luvadaxistat improves mismatch negativity in patients with schizophrenia in a randomized trial.
    Neuropsychopharmacology. 2023 Mar 16. doi: 10.1038/s41386-023-01560.
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    February 2023
  31. CHEN X, Song X, Ongur D, Du F, et al
    Association of default-mode network neurotransmitters and inter-network functional connectivity in first episode psychosis.
    Neuropsychopharmacology. 2023 Feb 14. doi: 10.1038/s41386-023-01546.
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    December 2022
  32. YANG C, Zhang W, Liu J, Yao L, et al
    Disrupted subcortical functional connectome gradient in drug-naive first-episode schizophrenia and the normalization effects after antipsychotic treatment.
    Neuropsychopharmacology. 2022 Dec 10. doi: 10.1038/s41386-022-01512.
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  33. EGERTON A, Griffiths K, Casetta C, Deakin B, et al
    Anterior cingulate glutamate metabolites as a predictor of antipsychotic response in first episode psychosis: data from the STRATA collaboration.
    Neuropsychopharmacology. 2022 Dec 1. doi: 10.1038/s41386-022-01508.
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    November 2022
  34. MOYA NA, Yun S, Fleps SW, Martin MM, et al
    The effect of selective nigrostriatal dopamine excess on behaviors linked to the cognitive and negative symptoms of schizophrenia.
    Neuropsychopharmacology. 2022 Nov 15. pii: 10.1038/s41386-022-01492.
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  35. FENG N, Palaniyappan L, Robbins TW, Cao L, et al
    Working memory processing deficit associated with a nonlinear response pattern of the anterior cingulate cortex in first-episode and drug-naive schizophrenia.
    Neuropsychopharmacology. 2022 Nov 14. pii: 10.1038/s41386-022-01499.
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    October 2022
  36. LENCZ T, Moyett A, Argyelan M, Barber AD, et al
    Frontal lobe fALFF measured from resting-state fMRI as a prognostic biomarker in first-episode psychosis.
    Neuropsychopharmacology. 2022 Oct 5. pii: 10.1038/s41386-022-01470.
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    September 2022
  37. VINOGRADOV S, Chafee MV, Lee E, Morishita H, et al
    Psychosis spectrum illnesses as disorders of prefrontal critical period plasticity.
    Neuropsychopharmacology. 2022 Sep 30. pii: 10.1038/s41386-022-01451.
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  38. HOWES OD, Cummings C, Chapman GE, Shatalina E, et al
    Neuroimaging in schizophrenia: an overview of findings and their implications for synaptic changes.
    Neuropsychopharmacology. 2022 Sep 2. pii: 10.1038/s41386-022-01426.
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    August 2022
  39. SCHWARZER JM, Meyhoefer I, Antonucci LA, Kambeitz-Ilankovic L, et al
    The impact of visual dysfunctions in recent-onset psychosis and clinical high-risk state for psychosis.
    Neuropsychopharmacology. 2022 Aug 18. pii: 10.1038/s41386-022-01385.
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    March 2022
  40. ALNAFISAH RS, Reigle J, Eladawi MA, O'Donovan SM, et al
    Assessing the effects of antipsychotic medications on schizophrenia functional analysis: a postmortem proteome study.
    Neuropsychopharmacology. 2022 Mar 30. pii: 10.1038/s41386-022-01310.
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  41. ZHAO Q, Cao H, Zhang W, Li S, et al
    A subtype of institutionalized patients with schizophrenia characterized by pronounced subcortical and cognitive deficits.
    Neuropsychopharmacology. 2022 Mar 8. pii: 10.1038/s41386-022-01300.
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  42. TSITSIPA E, Rogers J, Casalotti S, Belessiotis-Richards C, et al
    Selective 5HT3 antagonists and sensory processing: a systematic review.
    Neuropsychopharmacology. 2022;47:880-890.
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  43. DAO M, Stoveken HM, Cao Y, Martemyanov KA, et al
    The role of orphan receptor GPR139 in neuropsychiatric behavior.
    Neuropsychopharmacology. 2022;47:902-913.
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    February 2022
  44. SEHATPOUR P, Javitt DC, De Baun HM, Carlson M, et al
    Mismatch negativity as an index of target engagement for excitation/inhibition-based treatment development: a double-blind, placebo-controlled, randomized, single-dose cross-over study of the serotonin type-3 receptor antagonist CVN058.
    Neuropsychopharmacology. 2022;47:711-718.
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    January 2022
  45. KIMOTO S, Hashimoto T, Berry KJ, Tsubomoto M, et al
    Expression of actin- and oxidative phosphorylation-related transcripts across the cortical visuospatial working memory network in unaffected comparison and schizophrenia subjects.
    Neuropsychopharmacology. 2022 Jan 15. pii: 10.1038/s41386-022-01274.
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  46. CARREIRA FIGUEIREDO I, Borgan F, Pasternak O, Turkheimer FE, et al
    White-matter free-water diffusion MRI in schizophrenia: a systematic review and meta-analysis.
    Neuropsychopharmacology. 2022 Jan 15. pii: 10.1038/s41386-022-01272.
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    November 2021
  47. KIEMES A, Gomes FV, Cash D, Uliana DL, et al
    GABAA and NMDA receptor density alterations and their behavioral correlates in the gestational methylazoxymethanol acetate model for schizophrenia.
    Neuropsychopharmacology. 2021 Nov 6. pii: 10.1038/s41386-021-01213.
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    October 2021
  48. KIM M, Lee TH, Park H, Moon SY, et al
    Thalamocortical dysrhythmia in patients with schizophrenia spectrum disorder and individuals at clinical high risk for psychosis.
    Neuropsychopharmacology. 2021 Oct 4. pii: 10.1038/s41386-021-01180.
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  49. PELIN H, Ising M, Stein F, Meinert S, et al
    Identification of transdiagnostic psychiatric disorder subtypes using unsupervised learning.
    Neuropsychopharmacology. 2021;46:1895-1905.
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    September 2021
  50. TUOMINEN L, Romaniuk L, Milad MR, Goff DC, et al
    Impairment in acquisition of conditioned fear in schizophrenia.
    Neuropsychopharmacology. 2021 Sep 29. pii: 10.1038/s41386-021-01193.
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  51. MILLARD SJ, Bearden CE, Karlsgodt KH, Sharpe MJ, et al
    The prediction-error hypothesis of schizophrenia: new data point to circuit-specific changes in dopamine activity.
    Neuropsychopharmacology. 2021 Sep 29. pii: 10.1038/s41386-021-01188.
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  52. EUM S, Hill SK, Alliey-Rodriguez N, Stevenson JM, et al
    Genome-wide association study accounting for anticholinergic burden to examine cognitive dysfunction in psychotic disorders.
    Neuropsychopharmacology. 2021;46:1802-1810.
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  53. LAM M, Chen CY, Ge T, Xia Y, et al
    Identifying nootropic drug targets via large-scale cognitive GWAS and transcriptomics.
    Neuropsychopharmacology. 2021;46:1788-1801.
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    August 2021
  54. ABDALLAH CG, Mason GF
    Novel approaches to estimate prefrontal synaptic strength in vivo in humans: of relevance to depression, schizophrenia, and ketamine.
    Neuropsychopharmacology. 2021 Aug 2. pii: 10.1038/s41386-021-01122.
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  55. BRALTEN J, Mota NR, Klemann CJHM, De Witte W, et al
    Genetic underpinnings of sociability in the general population.
    Neuropsychopharmacology. 2021;46:1627-1634.
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    July 2021
  56. SMUCNY J, Dienel SJ, Lewis DA, Carter CS, et al
    Mechanisms underlying dorsolateral prefrontal cortex contributions to cognitive dysfunction in schizophrenia.
    Neuropsychopharmacology. 2021 Jul 20. pii: 10.1038/s41386-021-01089.
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  57. FERRARELLI F, Phillips ML
    PFC neuromodulation with theta burst stimulation to impact behavior and neural network activity in schizophrenia and bipolar disorder.
    Neuropsychopharmacology. 2021 Jul 7. pii: 10.1038/s41386-021-01086.
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  58. GOLDWASER EL, Chiappelli J, Kvarta MD, Du X, et al
    White matter in prolonged glucocorticoid response to psychological stress in schizophrenia.
    Neuropsychopharmacology. 2021 Jul 1. pii: 10.1038/s41386-021-01077.
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    June 2021
  59. AVRAM M, Grothe MJ, Meinhold L, Leucht C, et al
    Lower cholinergic basal forebrain volumes link with cognitive difficulties in schizophrenia.
    Neuropsychopharmacology. 2021 Jun 29. pii: 10.1038/s41386-021-01070.
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  60. TRONCHIN G, Akudjedu TN, Ahmed M, Holleran L, et al
    Correction to: Progressive subcortical volume loss in treatment-resistant schizophrenia patients after commencing clozapine treatment.
    Neuropsychopharmacology. 2021 Jun 24. pii: 10.1038/s41386-021-01062.
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    May 2021
  61. MODINOS G, Richter A, Egerton A, Bonoldi I, et al
    Interactions between hippocampal activity and striatal dopamine in people at clinical high risk for psychosis: relationship to adverse outcomes.
    Neuropsychopharmacology. 2021 May 3. pii: 10.1038/s41386-021-01019.
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    April 2021
  62. SEITZ-HOLLAND J, Seethaler M, Makris N, Rushmore J, et al
    The association of matrix metalloproteinase 9 (MMP9) with hippocampal volume in schizophrenia: a preliminary MRI study.
    Neuropsychopharmacology. 2021 Apr 8. pii: 10.1038/s41386-021-00997.
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