Amedeo's Top 20

Amedeo Smart

Independent Medical Education

14 July 2025

Multidisciplinary Journal Club

  1. Nicholls SJ, Nelson AJ, Ditmarsch M, Kastelein JJP, et al.
    Safety and Efficacy of Obicetrapib in Patients at High Cardiovascular Risk.
    N Engl J Med 2025.

  1. Luisi N, Sullivan PS, Sanchez T, Bradley H, et al.
    Use of COVIDTests.gov At-Home Test Kits Among Adults in a National Household Probability Sample - United States, 2022.
    MMWR Morb Mortal Wkly Rep 2023;72:445-449.

  2. Chong Lugon N, Rabiee A, Mezzacappa C, Kaplan DE, et al.
    Prognostic significance of mild ascites in patients with cirrhosis.
    Hepatology 2025.

  3. Phillips PPJ, Peloquin CA, Sterling TR, Kaur P, et al.
    Efficacy and Safety of Higher Doses of Levofloxacin for Multidrug-resistant Tuberculosis: A Randomized, Placebo-controlled Phase II Clinical Trial.
    Am J Respir Crit Care Med 2025;211:1277-1287.

  4. Legrand M, Jullien E, Kimmoun A, Geri G, et al.
    Iloprost for the Treatment of Severe Septic Shock with Persistent Hypoperfusion: A Double-Blind, Randomized Controlled Trial.
    Am J Respir Crit Care Med 2025;211:1211-1219.

  1. Cohen J.
    Left behind.
    Science 2025;389:18-23.

  2. Mekontso Dessap A, Ricard JD, Contou D, Desnos C, et al.
    Melatonin for prevention of delirium in patients receiving mechanical ventilation in the intensive care unit: a multiarm multistage adaptive randomized controlled clinical trial (DEMEL).
    Intensive Care Med 2025.

  3. Moyo M, Lawrence DS, Jafali J, Molloy SF, et al.
    Recent Antiretroviral Therapy Initiation Is Associated With Increased Mortality Risk in Human Immunodeficiency Virus-associated Cryptococcal Meningitis: An Analysis of Clinical Trial Data From Africa.
    Clin Infect Dis 2025.

  4. Burstad KM, Lamina T, Erickson A, Gholizadeh E, et al.
    Evaluation of dietary protein and amino acid requirements: a systematic review.
    Am J Clin Nutr 2025;122:285-305.

  5. Becker L, Bzhilyanskaya V, Sharman A, Moran M, et al.
    Intra-Arterial Versus Noninvasive Blood Pressure Monitoring: A Systematic Review and Meta-Analysis.
    Am J Crit Care 2025;34:e6-e23.

  1. Cagol A, Schaedelin S, Ocampo-Pineda M, Benkert P, et al.
    Comparative effectiveness of teriflunomide and ocrelizumab on smoldering activity in multiple sclerosis: an observational study in the Swiss Multiple Sclerosis Cohort.
    J Neurol 2025;272:491.

  2. Mezzanotte-Sharpe J, Hsu CY, Choi D, Sheffield H, et al.
    Adverse events in patients treated with neoadjuvant chemo/immunotherapy for triple negative breast cancer: results from seven academic medical centers.
    Breast Cancer Res Treat 2025.

  3. Hoilund-Carlsen PF, Alavi A, Costa T, Neve RL, et al.
    Is US residence a risk factor for Alzheimer's disease?
    J Alzheimers Dis 2025.

  4. Patel JJ, Martindale RG, McClave SA.
    Contemporary Rationale for Delivering Enteral Nutrition in Critically Ill Adults.
    Crit Care Med 2025;53:e1481-e1490.

  5. Siegler JE, Goicoechea EB, Penckofer M, Eklund K, et al.
    Outcomes of Patients With Embolic Stroke of Undetermined Source Treated With Antiplatelet Agents or Anticoagulation: A Multicenter Cohort Study.
    Neurology 2025;105:e213876.

  1. Zaccone T, Moiola L, Guerrieri S, Nozzolillo A, et al.
    Long-term effectiveness and safety of ocrelizumab: a single-centre real-world study.
    J Neurol 2025;272:481.

  2. Brown TT, Arao RF, Warsi M, Phanuphak N, et al.
    Bone Changes With Long-Acting Cabotegravir or Tenofovir Disoproxil Fumarate/Emtricitabine for HIV Prevention in Cisgender Men and Transgender Women: HPTN 083.
    Clin Infect Dis 2025.

  3. Greil ME, Barber JK, Temkin NR, Bonow RH, et al.
    External Ventricular Drain Versus Intraparenchymal Pressure Monitor in Severe Traumatic Brain Injury: A TRACK-TBI Study.
    Neurosurgery 2025.

  4. Davies EP, Tsuboi M, Evans J, Rowley J, et al.
    A global meta-analysis of gonorrhoea and chlamydia prevalence among men who have sex with men from 2000 to 2022.
    Int J STD AIDS 2025;36:611-621.

  5. Vercellino M, Marasciulo S, Bosa C, Rolando A, et al.
    Added value of spinal cord MRI in detecting active disease in non-relapsing progressive multiple sclerosis patients.
    J Neurol 2025;272:482.


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