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Zika Virus Infection

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Articles published in
J Virol
    April 2024
  1. FAN Y-C, Chen J-M, Chen Y-Y, Ke Y-D, et al
    Epitope(s) involving amino acids of the fusion loop of Japanese encephalitis virus envelope protein is(are) important to elicit protective immunity.
    J Virol. 2024;98:e0177323.
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  2. MOORE KM, Pelletier A-N, Lapp S, Metz A, et al
    Single-cell analysis reveals an antiviral network that controls Zika virus infection in human dendritic cells.
    J Virol. 2024 Apr 3:e0019424. doi: 10.1128/jvi.00194.
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    February 2024
  3. YUAN H, Rao J, Zhang J, Ye J, et al
    Japanese encephalitis virus inhibits superinfection of Zika virus in cells by the NS2B protein.
    J Virol. 2024 Feb 27:e0185923. doi: 10.1128/jvi.01859.
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  4. CHEN X, Li R-T, Chen R-Y, Shi P-D, et al
    The subgenomic flaviviral RNA suppresses RNA interference through competing with siRNAs for binding RISC components.
    J Virol. 2024;98:e0195423.
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    January 2024
  5. ZHANG H, Xiao W, Zhao M, Zhang Y, et al
    Characterization of CD8(+) T cells in immune-privileged organs of ZIKV-infected Ifnar1(-/-) mice.
    J Virol. 2024;98:e0078923.
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    December 2023
  6. MANZANO-ALVAREZ J, Terradas G, Holmes CJ, Benoit JB, et al
    Dehydration stress and Mayaro virus vector competence in Aedes aegypti.
    J Virol. 2023;97:e0069523.
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  7. KANG L, Xie H, Ye H, Jeyarajan AJ, et al
    Hsa_circ_0007321 regulates Zika virus replication through miR-492/NFKBID/NF-kappaB signaling pathway.
    J Virol. 2023 Dec 5:e0123223. doi: 10.1128/jvi.01232.
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    November 2023
  8. KIKAWA C, Cartwright-Acar CH, Stuart JB, Contreras M, et al
    The effect of single mutations in Zika virus envelope on escape from broadly neutralizing antibodies.
    J Virol. 2023 Nov 9:e0141423. doi: 10.1128/jvi.01414.
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    October 2023
  9. JAEGER AS, Marano J, Riemersma KK, Castaneda D, et al
    Gain without pain: adaptation and increased virulence of Zika virus in vertebrate host without fitness cost in mosquito vector.
    J Virol. 2023 Oct 6:e0116223. doi: 10.1128/jvi.01162.
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    September 2023
  10. LIU LB, Yang W, Chang JT, Fan DY, et al
    Zika virus infection leads to hormone deficiencies of the hypothalamic-pituitary-gonadal axis and diminished fertility in mice.
    J Virol. 2023 Sep 21:e0100623. doi: 10.1128/jvi.01006.
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    May 2023
  11. JEONG GU, Lee S, Kim DY, Lyu J, et al
    Zika Virus Infection Induces Interleukin-1beta-Mediated Inflammatory Responses by Macrophages in the Brain of an Adult Mouse Model.
    J Virol. 2023 May 16:e0055623. doi: 10.1128/jvi.00556.
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  12. LU AY, Gustin A, Newhouse D, Gale M Jr, et al
    Viral Protein Accumulation of Zika Virus Variants Links with Regulation of Innate Immunity for Differential Control of Viral Replication, Spread, and Response to Interferon.
    J Virol. 2023 May 10:e0198222. doi: 10.1128/jvi.01982.
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    March 2023
  13. LI XD, Deng CL, Yuan ZM, Ye HQ, et al
    Correction for Li et al., "Different Degrees of 5'-to-3' DAR Interactions Modulate Zika Virus Genome Cyclization and Host-Specific Replication".
    J Virol. 2023 Mar 8:e0030123. doi: 10.1128/jvi.00301.
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    February 2023
  14. SAKABE S, Witwit H, Khafaji R, Cubitt B, et al
    Chaperonin TRiC/CCT Participates in Mammarenavirus Multiplication in Human Cells via Interaction with the Viral Nucleoprotein.
    J Virol. 2023;97:e0168822.
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  15. HE MJ, Wang HJ, Yan XL, Lou YN, et al
    Key Residue in the Precursor Region of M Protein Contributes to the Neurovirulence and Neuroinvasiveness of the African Lineage of Zika Virus.
    J Virol. 2023 Feb 22:e0180122. doi: 10.1128/jvi.01801.
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    January 2023
  16. DE JESUS-GONZALEZ LA, Palacios-Rapalo SN, Reyes-Ruiz JM, Osuna-Ramos JF, et al
    Nucleo-Cytoplasmic Transport of ZIKV Non-Structural 3 Protein Is Mediated by Importin-alpha/beta and Exportin CRM-1.
    J Virol. 2023;97:e0177322.
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  17. SAHOO BR, Crook AA, Pattnaik A, Torres-Gerena AD, et al
    Redox Regulation and Metabolic Dependency of Zika Virus Replication: Inhibition by Nrf2-Antioxidant Response and NAD(H) Antimetabolites.
    J Virol. 2023 Jan 23:e0136322. doi: 10.1128/jvi.01363.
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  18. BRUSTOLIN M, Pujhari S, Terradas G, Werling K, et al
    In Vitro and In Vivo Coinfection and Superinfection Dynamics of Mayaro and Zika Viruses in Mosquito and Vertebrate Backgrounds.
    J Virol. 2023 Jan 4:e0177822. doi: 10.1128/jvi.01778.
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    November 2022
  19. CHENG ML, Yang YX, Liu ZY, Wen D, et al
    Pathogenicity and Structural Basis of Zika Variants with Glycan Loop Deletions in the Envelope Protein.
    J Virol. 2022 Nov 15:e0087922. doi: 10.1128/jvi.00879.
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    October 2022
  20. LI S, Armstrong N, Zhao H, Cruz-Cosme R, et al
    Zika Virus Infection Downregulates Connexin 43, Disrupts the Cardiomyocyte Gap Junctions and Induces Heart Diseases in A129 Mice.
    J Virol. 2022 Oct 13:e0137322. doi: 10.1128/jvi.01373.
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  21. LO NTN, Roodsari SZ, Tin NL, Wong MP, et al
    Molecular Determinants of Tissue Specificity of Flavivirus Nonstructural Protein 1 Interaction with Endothelial Cells.
    J Virol. 2022;96:e0066122.
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    September 2022
  22. PAGANI I, Ottoboni L, Podini P, Ghezzi S, et al
    Heparin Protects Human Neural Progenitor Cells from Zika Virus-Induced Cell Death While Preserving Their Differentiation into Mature Neuroglial Cells.
    J Virol. 2022 Sep 19:e0112222. doi: 10.1128/jvi.01122.
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    August 2022
  23. LOPEZ CA, Dulson SJ, Lazear HM
    Zika Virus Replicates in the Vagina of Mice with Intact Interferon Signaling.
    J Virol. 2022 Aug 30:e0121922. doi: 10.1128/jvi.01219.
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  24. LENSINK MJ, Li Y, Lequime S
    Aquatic Flaviviruses.
    J Virol. 2022 Aug 17:e0043922. doi: 10.1128/jvi.00439.
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  25. HAN Y, Bai X, Liu S, Zhu J, et al
    XAF1 Protects Host against Emerging RNA Viruses by Stabilizing IRF1-Dependent Antiviral Immunity.
    J Virol. 2022 Aug 16:e0077422. doi: 10.1128/jvi.00774.
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    June 2022
  26. CARABALLO GI, Rosales R, Viettri M, Castillo JM, et al
    The Dengue Virus Nonstructural Protein 1 (NS1) Interacts with the Putative Epigenetic Regulator DIDO1 to Promote Flavivirus Replication in Mosquito Cells.
    J Virol. 2022;96:e0070422.
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    May 2022
  27. TSUJI I, Vang F, Dominguez D, Karwal L, et al
    Somatic Hypermutation and Framework Mutations of Variable Region Contribute to Anti-Zika Virus-Specific Monoclonal Antibody Binding and Function.
    J Virol. 2022 May 16:e0007122. doi: 10.1128/jvi.00071.
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  28. RIEMERSMA KK, Jaeger AS, Crooks CM, Braun KM, et al
    Correction for Riemersma et al., "Rapid Evolution of Enhanced Zika Virus Virulence during Direct Vertebrate Transmission Chains".
    J Virol. 2022 May 2:e0050122. doi: 10.1128/jvi.00501.
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    April 2022
  29. TESLA B, Powers JS, Barnes Y, Lakhani S, et al
    Temperate Conditions Limit Zika Virus Genome Replication.
    J Virol. 2022 Apr 25:e0016522. doi: 10.1128/jvi.00165.
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  30. RYCHLOWSKA M, Agyapong A, Weinfeld M, Schang LM, et al
    Zika Virus Induces Mitotic Catastrophe in Human Neural Progenitors by Triggering Unscheduled Mitotic Entry in the Presence of DNA Damage While Functionally Depleting Nuclear PNKP.
    J Virol. 2022 Apr 12:e0033322. doi: 10.1128/jvi.00333.
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    March 2022
  31. LANGENDRIES L, Jacobs S, Abdelnabi R, Verwimp S, et al
    Perturbation of Alphavirus and Flavivirus Infectivity by Components of the Bacterial Cell Wall.
    J Virol. 2022;96:e0006022.
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  32. LI S, Wang D, Ghulam A, Li X, et al
    Tracking the Replication-Competent Zika Virus with Tetracysteine-Tagged Capsid Protein in Living Cells.
    J Virol. 2022 Mar 14:e0184621. doi: 10.1128/jvi.01846.
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  33. ALCALA AC, Maravillas JL, Meza D, Ramirez OT, et al
    Dengue Virus NS1 Uses Scavenger Receptor B1 as a Cell Receptor in Cultured Cells.
    J Virol. 2022;96:e0166421.
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    February 2022
  34. HERRLEIN ML, Schmanke P, Elgner F, Sabino C, et al
    Catch Me if You Can: the Crosstalk of Zika Virus and the Restriction Factor Tetherin.
    J Virol. 2022;96:e0211721.
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    January 2022
  35. RANGEL MV, Catanzaro N, Thannickal SA, Crotty KA, et al
    Structurally Conserved Domains between Flavivirus and Alphavirus Fusion Glycoproteins Contribute to Replication and Infectious-Virion Production.
    J Virol. 2022;96:e0177421.
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    November 2021
  36. ZHANG Y, Sheng Z, Gao N, Wu N, et al
    Zika virus infection in the ovary induces continuously elevated progesterone level and compromises conception in interferon alpha/beta receptor-deficient mice.
    J Virol. 2021 Nov 3:JVI0118921. doi: 10.1128/JVI.01189.
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    October 2021
  37. PARISIEN JP, Lenoir JJ, Alvarado G, Horvath CM, et al
    The Human STAT2 Coiled-Coil Domain Contains a Degron for Zika Virus Interferon Evasion.
    J Virol. 2021 Oct 13:JVI0130121. doi: 10.1128/JVI.01301.
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    September 2021
  38. SHUE B, Chiramel AI, Cerikan B, To TH, et al
    Genome-wide CRISPR screen identifies RACK1 as a critical host factor for flavivirus replication.
    J Virol. 2021 Sep 29:JVI0059621. doi: 10.1128/JVI.00596.
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  39. RIVA L, Goellner S, Biering SB, Huang CT, et al
    The compound SBI-0090799 inhibits Zika virus (ZIKV) infection by blocking de novo formation of the membranous replication compartment.
    J Virol. 2021 Sep 1:JVI0099621. doi: 10.1128/JVI.00996.
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  40. SHAROV V, Rezelj VV, Galatenko VV, Titievsky A, et al
    Intra and inter-cellular modeling of dynamic interaction between Zika virus and its naturally occurring defective viral genomes.
    J Virol. 2021 Sep 1:JVI0097721. doi: 10.1128/JVI.00977.
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  41. GAVINO-LEOPOLDINO D, Figueiredo CM, da Silva MOL, Barcellos LG, et al
    Skeletal muscle is an early site of Zika virus replication and injury impairing myogenesis.
    J Virol. 2021 Sep 1:JVI0090421. doi: 10.1128/JVI.00904.
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    August 2021
  42. BOHM EK, Vangorder-Braid JT, Jaeger AS, Moriarty RV, et al
    Zika virus infection of pregnant Ifnar1(-/-) mice triggers strain-specific differences in fetal outcomes.
    J Virol. 2021 Aug 11:JVI0081821. doi: 10.1128/JVI.00818.
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  43. SABINO C, Bender D, Herrlein ML, Hildt E, et al
    The epidermal growth factor receptor is a relevant host factor in the early stages of Zika virus life cycle in vitro.
    J Virol. 2021 Aug 11:JVI0119521. doi: 10.1128/JVI.01195.
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    July 2021
  44. JIMENEZ OA, Narasipura SD, Barbian HJ, Albalawi YA, et al
    beta-catenin restricts Zika virus internalization by downregulating Axl.
    J Virol. 2021 Jul 14:JVI0070521. doi: 10.1128/JVI.00705.
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  45. JIA X, Guo J, Yuan W, Sun L, et al
    Mechanism through Which Retrocyclin Targets Flavivirus Multiplication.
    J Virol. 2021;95:e0056021.
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  46. HSIEH SC, Tsai WY, Tsai JJ, Stone M, et al
    Identification of anti-premembrane antibody as a serocomplex-specific marker to discriminate Zika, dengue and West Nile virus infections.
    J Virol. 2021 Jul 7:JVI0061921. doi: 10.1128/JVI.00619.
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    June 2021
  47. HASSERT M, Steffen TL, Scroggins S, Coleman AK, et al
    Prior heterologous flavivirus exposure results in reduced pathogenesis in a mouse model of Zika virus infection.
    J Virol. 2021 Jun 2:JVI0057321. doi: 10.1128/JVI.00573.
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  48. CROOKS CM, Weiler AM, Rybarczyk SL, Bliss M, et al
    African-lineage Zika virus replication dynamics and maternal-fetal interface infection in pregnant rhesus macaques.
    J Virol. 2021 Jun 2:JVI0222020. doi: 10.1128/JVI.02220.
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    April 2021
  49. YE X, Liu X, Shu T, Deng W, et al
    A Live-attenuated Zika Virus Vaccine with High Production Capacity Confers Effective Protection in Neonatal Mice.
    J Virol. 2021 Apr 28. pii: JVI.00383-21. doi: 10.1128/JVI.00383.
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    March 2021
  50. SCHOUEST B, Grifoni A, Pham J, Mateus J, et al
    Pre-existing T cell memory against Zika virus.
    J Virol. 2021 Mar 31. pii: JVI.00132-21. doi: 10.1128/JVI.00132.
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  51. PLOCIENNIKOWSKA A, Frankish J, Moraes T, Del Prete D, et al
    TLR3 activation by Zika virus stimulates inflammatory cytokine production which dampens the antiviral response induced by RIG-I-like receptors.
    J Virol. 2021 Mar 3. pii: JVI.01050-20. doi: 10.1128/JVI.01050.
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    February 2021
  52. GRAHAM SD, Tu HA, McElvany BD, Graham NR, et al
    A novel antigenic site spanning domains I and III of the Zika virus envelope glycoprotein is the target of strongly neutralizing human monoclonal antibodies.
    J Virol. 2021 Feb 17. pii: JVI.02423-20. doi: 10.1128/JVI.02423.
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  53. RIEMERSMA KK, Jaeger AS, Crooks CM, Braun KM, et al
    Rapid evolution of enhanced Zika virus virulence during direct vertebrate transmission chains.
    J Virol. 2021 Feb 3. pii: JVI.02218-20. doi: 10.1128/JVI.02218.
    >> Share

  54. HAN X, Wang J, Yang Y, Qu S, et al
    Zika virus infection induced apoptosis by modulating the recruitment and activation of pro-apoptotic protein Bax.
    J Virol. 2021 Feb 3. pii: JVI.01445-20. doi: 10.1128/JVI.01445.
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    December 2020
  55. SEXTON NR, Bellis ED, Murrieta RA, Spangler MC, et al
    Genome number and size polymorphism in Zika virus infectious units.
    J Virol. 2020 Dec 16. pii: JVI.00787-20. doi: 10.1128/JVI.00787.
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  56. CLARK AE, Zhu Z, Krach F, Rich JN, et al
    Zika virus is transmitted in neural progenitor cells via cell-to-cell spread and infection is inhibited by the autophagy inducer trehalose.
    J Virol. 2020 Dec 16. pii: JVI.02024-20. doi: 10.1128/JVI.02024.
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    October 2020
  57. DE LORENZO G, Tandavanitj R, Doig J, Setthapramote C, et al
    Zika virus-like particles bearing covalent dimer of envelope protein protect mice from lethal challenge.
    J Virol. 2020 Oct 7. pii: JVI.01415-20. doi: 10.1128/JVI.01415.
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    September 2020
  58. LEMOS D, Stuart JB, Louie W, Singapuri A, et al
    Two sides of a coin: a Zika virus mutation selected in pregnant rhesus macaques promotes fetal infection in mice but at a cost of reduced fitness in nonpregnant macaques and diminished transmissibility by vectors.
    J Virol. 2020 Sep 30. pii: JVI.01605-20. doi: 10.1128/JVI.01605.
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  59. HUANG Y, Lin Q, Huo Z, Chen C, et al
    Inositol requiring enzyme 1alpha promotes Zika virus infection through regulating stearoyl-CoA desaturase 1 mediated lipid metabolism.
    J Virol. 2020 Sep 23. pii: JVI.01229-20. doi: 10.1128/JVI.01229.
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  60. SAHOO BR, Pattnaik A, Annamalai AS, Franco R, et al
    Mechanistic Target of Rapamycin (mTOR) Signaling Activation Antagonizes Autophagy to Facilitate Zika Virus Replication.
    J Virol. 2020 Sep 2. pii: JVI.01575-20. doi: 10.1128/JVI.01575.
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    August 2020
  61. MCDONALD EM, Anderson J, Wilusz J, Ebel GD, et al
    Zika virus replication in myeloid cells during acute infection is vital to viral dissemination and pathogenesis in a mouse model.
    J Virol. 2020 Aug 26. pii: JVI.00838-20. doi: 10.1128/JVI.00838.
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  62. CARBAUGH DL, Zhou S, Sanders W, Moorman NJ, et al
    Two genetic differences between closely-related Zika virus strains determine pathogenic outcome in mice.
    J Virol. 2020 Aug 12. pii: JVI.00618-20. doi: 10.1128/JVI.00618.
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  63. GHARBI-AYACHI A, Santhanakrishnan S, Wong YH, Chan KWK, et al
    Non-Nucleoside Inhibitors of Zika virus RNA-dependent RNA polymerase.
    J Virol. 2020 Aug 12. pii: JVI.00794-20. doi: 10.1128/JVI.00794.
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    July 2020
  64. CONDE JN, Schutt W, Mladinich M, Sohn SY, et al
    NS5 Sumoylation Directs Nuclear Responses that Permit Zika Virus to Persistently Infect Human Brain Microvascular Endothelial Cells.
    J Virol. 2020 Jul 22. pii: JVI.01086-20. doi: 10.1128/JVI.01086.
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    June 2020
  65. PALLARES H, Costa Navarro GS, Villordo S, Merwaiss F, et al
    Zika Virus sfRNA Generation Requires Cooperativity between Duplicated RNA Structures that Are Essential for Productive Infection in Human Cells.
    J Virol. 2020 Jun 24. pii: JVI.00343-20. doi: 10.1128/JVI.00343.
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  66. LI A, Xue M, Attia Z, Yu J, et al
    Vesicular stomatitis virus and DNA vaccines expressing Zika virus nonstructural protein 1 (NS1) induce substantial but not sterilizing protection against Zika virus infection.
    J Virol. 2020 Jun 17. pii: JVI.00048-20. doi: 10.1128/JVI.00048.
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    April 2020
  67. EVANS AS, Lennemann NJ, Coyne CB
    BPIFB3 Regulates Endoplasmic Reticulum Morphology To Facilitate Flavivirus Replication.
    J Virol. 2020;94.
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    March 2020
  68. GURUNG S, Nadeau H, Maxted M, Peregrine J, et al
    MATERNAL ZIKA VIRUS (ZIKV) INFECTION FOLLOWING VAGINAL INOCULATION WITH ZIKV-INFECTED SEMEN IN THE TIMED-PREGNANT OLIVE BABOON.
    J Virol. 2020 Mar 18. pii: JVI.00058-20. doi: 10.1128/JVI.00058.
    >> Share

  69. GRIFONI A, Voic H, Dhanda SK, Kidd CK, et al
    T cell responses induced by attenuated flavivirus vaccination are specific and show limited cross-reactivity with other flavivirus species.
    J Virol. 2020 Mar 4. pii: JVI.00089-20. doi: 10.1128/JVI.00089.
    >> Share

    February 2020
  70. MARTINEZ LE, Garcia G Jr, Contreras D, Gong D, et al
    Zika Virus Mucosal Infection Provides Protective Immunity.
    J Virol. 2020 Feb 12. pii: JVI.00067-20. doi: 10.1128/JVI.00067.
    >> Share

    December 2019
  71. LI XD, Deng CL, Yuan ZM, Ye HQ, et al
    Different Degrees of 5'-3' DAR Interactions Modulate Zika Virus Genome Cyclization and Host Specific Replication.
    J Virol. 2019 Dec 11. pii: JVI.01602-19. doi: 10.1128/JVI.01602.
    >> Share

  72. MORENO GK, Newman CM, Koenig MR, Mohns MS, et al
    Long-term protection of rhesus macaques from Zika virus reinfection.
    J Virol. 2019 Dec 4. pii: JVI.01881-19. doi: 10.1128/JVI.01881.
    >> Share

    November 2019
  73. WEISBLUM Y, Oiknine-Djian E, Vorontsov OM, Haimov-Kochman R, et al
    Correction for Weisblum et al., "Zika Virus Infects Early- and Midgestation Human Maternal Decidual Tissues, Inducing Distinct Innate Tissue Responses in the Maternal-Fetal Interface".
    J Virol. 2019;93.
    >> Share

  74. MANET C, Simon-Loriere E, Jouvion G, Hardy D, et al
    Genetic diversity of Collaborative Cross mice controls viral replication, clinical severity and brain pathology induced by Zika virus infection, independently of Oas1b.
    J Virol. 2019 Nov 6. pii: JVI.01034-19. doi: 10.1128/JVI.01034.
    >> Share

    October 2019
  75. PEREGRINE J, Gurung S, Lindgren MC, Husain S, et al
    Zika virus infection, reproductive organ targeting, and semen transmission in the male olive baboon.
    J Virol. 2019 Oct 9. pii: JVI.01434-19. doi: 10.1128/JVI.01434.
    >> Share

    February 2019
  76. ROSALES RAMIREZ R, Ludert JE
    The Dengue Virus Nonstructural Protein 1 (NS1) Is Secreted from Mosquito Cells in Association with the Intracellular Cholesterol Transporter Chaperone Caveolin Complex.
    J Virol. 2019;93.
    >> Share

    November 2018
  77. WANG Y, Chen X, Xie J, Zhou S, et al
    RNA helicase A is an important host factor involved in dengue virus replication.
    J Virol. 2018 Nov 21. pii: JVI.01306-18. doi: 10.1128/JVI.01306.
    >> Share


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