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Articles published in
Am Heart J
    January 2027
  1. RAKOWSKI T, Gladys K, Siudak Z, Malinowski K, et al
    Temporal trends and clinical characteristics of drug-coated balloon angioplasty for de novo coronary lesions: A 6-year analysis from the ORPKI registry.
    Am Heart J. 2027;303:107609.
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  2. VAN DEN EYNDE J, Egbe AC, Van De Bruaene A, De Meester P, et al
    Accuracy of indirect Fick method for systemic flow calculation in adults with a Fontan circulation.
    Am Heart J. 2027;303:107608.
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  3. EGBE AC, Saad S, Hodhod A, Rashwan R, et al
    Guideline-directed medical therapy and clinical outcomes in adults with Fontan palliation and systemic ventricular systolic dysfunction.
    Am Heart J. 2027;303:107589.
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    December 2026
  4. LEE JY, Parvathinathan G, Liu S, Etemadi A, et al
    Efficacy and safety of revascularization in patients with chronic limb-threatening ischemia by kidney function.
    Am Heart J. 2026;302:107550.
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    November 2026
  5. GAUDINO M, Stone GW, Puskas J, Krieger K, et al
    Lessons learned from the feasibility phase of the REvascularization CHoices Among Under-Represented Groups Evaluation (RECHARGE) trial program.
    Am Heart J. 2026;301:107515.
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    October 2026
  6. D'ASCENZO F, De Filippo O, Pelliccia F, Pasceri V, et al
    Potentially futile outcome after uncomplicated TAVI: Insights from the TRITAVI registry.
    Am Heart J. 2026;300:107488.
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  7. BROYD CJ, Arunothayaraj S, Scheller B, Eccleshall S, et al
    The European bifurcation club randomized trial of stepwise provisional stenting vs drug-coated balloon therapy for nonleft main true coronary bifurcations: The EBC DCB trial.
    Am Heart J. 2026;300:107463.
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    July 2026
  8. RODRIGO ZONI C, Mukherjee D, Gulati M
    Reconsidering Fibrinolysis in Selected Patients with Non-ST-Elevation Acute Coronary Syndrome: A Hypothesis-Generating, Research-Based Framework.
    Am Heart J. 2026 Jul 31:107548. doi: 10.1016/j.ahj.2026.107548.
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  9. OPOLSKI MP, Spiewak M, Machaj F, Borzuta H, et al
    Antegrade dissection and re-entry versus retrograde strategy in chronic total occlusion percutaneous coronary intervention: Rationale and design of the ADRENALINE randomized study.
    Am Heart J. 2026 Jul 11:107538. doi: 10.1016/j.ahj.2026.107538.
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  10. AROW Z, Oliva O, Seyeddi SS, Bonfils L, et al
    Assessment of the gradient gap after TAVR with balloon and self-expandable valves: Analysis of a large patient cohort.
    Am Heart J. 2026;297:107428.
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  11. CASAZZA R, Hashmi A, Fogel J, Shani J, et al
    Operator radiation exposure comparing left-radial artery and right-radial artery approaches: A systematic review and meta-analysis.
    Am Heart J. 2026;297:107385.
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    June 2026
  12. MURO FMD, Raona V, Sartori S, Smith K, et al
    Prognostic Impact of Combined Inflammatory Markers in Patients Undergoing Percutaneous Coronary Intervention.
    Am Heart J. 2026 Jun 21:107519. doi: 10.1016/j.ahj.2026.107519.
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  13. CORTESE B, Mohammed AA, Malakouti S, Sivalingam J, et al
    Antiplatelet treatment after drug-coated balloon treatment: Review of the current evidence and future perspectives.
    Am Heart J. 2026;296:107361.
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  14. LIAO W, Rashid M, Brookes CL, Barber S, et al
    Study design for an emulated trial of a 2 arm, parallel, stratified, adaptive, RCT of CABG versus PCI in people requiring myocardial revascularization at high risk (High-Risk REVASC).
    Am Heart J. 2026;296:107368.
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    May 2026
  15. COSTA G, Laterra G, Sammartino S, De Backer O, et al
    Progression of bicuspid-related aortopathy in patients undergoing Transcatheter Aortic Valve Implantation: rationale and design of the international, multicenter PROSPERO-TAVI registry.
    Am Heart J. 2026 May 27:107494. doi: 10.1016/j.ahj.2026.107494.
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  16. TOMII D, Lanz J, Heg D, Thiele H, et al
    Relationship between baseline patient-reported health status and patient-centered outcomes after Transcatheter Aortic Valve Replacement.
    Am Heart J. 2026 May 26:107495. doi: 10.1016/j.ahj.2026.107495.
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  17. CHI KY, Karthikeyan A, Chang Y, Lee PL, et al
    Direct Oral Anticoagulant Monotherapy versus Combination Therapy with Antiplatelets in Chronic Coronary Syndrome Patients with Prior Percutaneous Coronary Intervention Requiring Anticoagulation: A Meta-Analysis.
    Am Heart J. 2026 May 17:107492. doi: 10.1016/j.ahj.2026.107492.
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  18. HOSSEINI F, Kang M, Segal T, Singer J, et al
    Impact of Malnutrition on Outcomes among elderly ST-Elevation Myocardial Infarction Patients receiving Primary PCI.
    Am Heart J. 2026 May 15:107489. doi: 10.1016/j.ahj.2026.107489.
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  19. WANG W, Gu Y, Wang D, Zhang W, et al
    High-Intensity Interval Training Combined with Moderate-Intensity Continuous Training in Post-PCI Acute Myocardial Infarction Patients: A Randomized Controlled Trial.
    Am Heart J. 2026 May 8:107472. doi: 10.1016/j.ahj.2026.107472.
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    April 2026
  20. WOELDERS ECI, Yosofi B, Peeters DAM, von Birgelen C, et al
    Short-term outcomes of ticagrelor monotherapy after primary percutaneous coronary intervention for ST-elevation myocardial infarction; a randomized pilot study.
    Am Heart J. 2026 Apr 28:107460. doi: 10.1016/j.ahj.2026.107460.
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  21. JANSSEN S, Luijkx JJP, Swinnen W, Vriesendorp P, et al
    Direct oral anticoagulation interruption versus continuation in patients undergoing elective invasive coronary angiography or percutaneous coronary intervention: design and rationale of the South Limburg Myocardial Infarction study group trial 2 (SLIM
    Am Heart J. 2026 Apr 27:107462. doi: 10.1016/j.ahj.2026.107462.
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  22. ELBENAWI H, Hassan I, Abdelgalil MS, Hanna M, et al
    Cerebral Embolic Protection Devices for Transcatheter Aortic Valve Replacement: A Meta-Analysis and Trial Sequential Analysis.
    Am Heart J. 2026 Apr 24:107449. doi: 10.1016/j.ahj.2026.107449.
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  23. JIN IT, Lee SH, Yun KH, Kim W, et al
    Optimal antiplatelet strategy in patients with advanced chronic kidney disease undergoing drug-eluting stent implantation: Design and rationale of the randomized ADAPT-CKD trial.
    Am Heart J. 2026 Apr 1:107437. doi: 10.1016/j.ahj.2026.107437.
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    March 2026
  24. SORENSEN LM, Reinert MS, Raja AA, de Backer O, et al
    Design and rationale of the EMPagliflozin after Aortic Valve Replacement (EMPAVR) study: a randomized clinical trial.
    Am Heart J. 2026 Mar 26:107432. doi: 10.1016/j.ahj.2026.107432.
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  25. GENEREUX P, Makkar RR, Bax JJ, Pibarot P, et al
    Design and rationale of the prospective, randomized, controlled trial to assess the management of moderate aortic stenosis by clinical surveillance or transcatheter aortic valve replacement: The PROGRESS Trial.
    Am Heart J. 2026;297:107433.
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  26. POLETTI E, Thotakura S, Kearney KE, Lombardi WL, et al
    Comparative Validation of Risk Scores for In-Hospital Complications Following Chronic Total Occlusion Percutaneous Coronary Intervention.
    Am Heart J. 2026 Mar 19:107427. doi: 10.1016/j.ahj.2026.107427.
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  27. DIMAGLI A, Redfors B, Gaudino M
    Trial Event Rate Assumption and Noninferiority Margin in Comparative Trials of Aortic Valve Replacement.
    Am Heart J. 2026 Mar 17:107425. doi: 10.1016/j.ahj.2026.107425.
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  28. IGLESIAS JF, Roffi M, Heg D, Muller O, et al
    IMPACT OF TOTAL STENT LENGTH ON LONG-TERM OUTCOMES WITH DIFFERENT NEWER-GENERATION DRUG-ELUTING STENT DESIGNS IN ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION: A SUBGROUP ANALYSIS FROM THE BIOSTEMI ES RANDOMIZED TRIAL.
    Am Heart J. 2026 Mar 9:107421. doi: 10.1016/j.ahj.2026.107421.
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  29. KIM HJ, Song TJ, Park MS, Baek JH, et al
    Design and Rationale of the Clinical trial to obtain the highest efficacy of dual antiplatelet therapy after carotid artery stenting in high bleeding risk patients (CHET): a multicenter, randomized, open-label, superiority trial.
    Am Heart J. 2026 Mar 7:107418. doi: 10.1016/j.ahj.2026.107418.
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  30. PIVATO CA, Mincione G, Gramss L, Pacchioni A, et al
    Early oral anticoagulation monotherapy after PCI: Insights from the POEM trial.
    Am Heart J. 2026;293:107309.
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    February 2026
  31. THIM T, Nissen H, Niemela M, Eftekhari A, et al
    Design and rationale of the COMPARE-TAVI 2 trial: An all-comers head-to-head comparison of Evolut FX+ and Sapien 3 Ultra Resilia transcatheter heart valves.
    Am Heart J. 2026 Feb 23:107387. doi: 10.1016/j.ahj.2026.107387.
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  32. HEUTS S, Pustjens TFS, Lux A, Gabrio A, et al
    Probabilities of treatment effects in complete or culprit-only revascularization for NSTEMI: a Bayesian re-analysis of the SLIM trial.
    Am Heart J. 2026 Feb 5:107369. doi: 10.1016/j.ahj.2026.107369.
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    January 2026
  33. ARMSTRONG PW, Zheng Y, Welsh RC, Sinnaeve PR, et al
    Primary Percutaneous Coronary Intervention within the First Hour: Insights from Early-Treated Patients with ST-Elevation Myocardial Infarction.
    Am Heart J. 2026 Jan 29:107363. doi: 10.1016/j.ahj.2026.107363.
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  34. CHEN X, Li S, Wang B, Chen G, et al
    Staged interventional strategies for acute ST-segment elevation myocardial infarction patient with multi-vessel disease: Rationale and design of a multicenter, randomized STAGED trial.
    Am Heart J. 2026 Jan 13:107352. doi: 10.1016/j.ahj.2026.107352.
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  35. DILETTI R, Daemen J, Faurie B, Barbierato M, et al
    Intravascular Ultrasound Guidance for Complex High-Risk Indicated Procedures: the IVUS CHIP Trial study design.
    Am Heart J. 2026 Jan 3:107339. doi: 10.1016/j.ahj.2026.107339.
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  36. SHAH AH, Armstrong HK, Mittal I, Reimer A, et al
    IMpact of therapY using coleSevelam treatment reducing bile acids in patients with fonTan cIrCulation (MYSTIC): Rationale and study design.
    Am Heart J. 2026;291:81-88.
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  37. TSIGKAS G, Trigka-Vasilakopoulou A, Apostolos A, Papafaklis M, et al
    Distal versus conventional transradial artery access for coronary catheterization in patients with STEMI (DR-STEMI): Rationale and design of an international, multicenter, randomized trial.
    Am Heart J. 2026;291:73-80.
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    December 2025
  38. CHOPARD R, Hobohm L, Barco S, Bangalore S, et al
    Large-bore mechanical thrombectomy vs standard of care for acute high-risk pulmonary embolism: rationale and design of the PERSEVERE randomized controlled trial.
    Am Heart J. 2025 Dec 24:107331. doi: 10.1016/j.ahj.2025.107331.
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  39. D'ENTREMONT MA, Lee SF, Wijeysundera HC, Tsang MB, et al
    Design and Rationale of the HD PCI Trial: A Cluster Randomized Crossover Trial of Higher vs. Lower Dose Heparin for Elective Percutaneous Coronary Intervention.
    Am Heart J. 2025 Dec 22:107330. doi: 10.1016/j.ahj.2025.107330.
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  40. ALSAIED T, Li R, Grant H, Schiff MD, et al
    Defining diastolic dysfunction post-Fontan: Threshold, risk factors, and associations with outcomes.
    Am Heart J. 2025;290:288-296.
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  41. ABDELHALIM AT, Reddy YVN, Miranda WR, Kamath PS, et al
    Prognostic value of liver biomarker scores for risk stratification in adults with Fontan palliation.
    Am Heart J. 2025;290:170-179.
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  42. LI Y, Schiff M, Olivieri LJ, Christopher AB, et al
    The long-term effect of the Fontan fenestration on clinical outcomes: A FORCE registry study.
    Am Heart J. 2025;290:105-114.
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  43. GALLEGOS FN, Bernstein D, Punn R, Long J, et al
    Systolic performance of the single ventricle, exercise capacity, and endothelial function in pediatric Fontan patients.
    Am Heart J. 2025;290:58-68.
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    November 2025
  44. SHAN J, Gao J, Chen Y, Ji H, et al
    Efficacy and Safety of Postoperative Autologous Blood Transfusion in Cardiac Surgery (RESCUE): Rationale, Design, and Study Protocol of a Multicenter Randomized Controlled Trial.
    Am Heart J. 2025 Nov 27:107313. doi: 10.1016/j.ahj.2025.107313.
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  45. LINGAMSETTY SSP, Medarametla RVSK, Prajapati K, Jitta SR, et al
    Effects of Supersaturated Oxygen Therapy on Infarct Size and Microvascular Obstruction Following Myocardial Infarction: A Systematic Review and Meta-Analysis.
    Am Heart J. 2025 Nov 24:107311. doi: 10.1016/j.ahj.2025.107311.
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  46. LI J, Wang ZY, Yan J, Li WH, et al
    Prospective, multicenter, randomized controlled study on the efficacy and safety of intravascular ultrasound-guided drug-coated balloon for de novo small-vessel coronary lesions: Design and rationale of the DCB-IVUS trial.
    Am Heart J. 2025 Nov 18:107307. doi: 10.1016/j.ahj.2025.107307.
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  47. VAN DEN ENDEN AJM, van den Dorpel MMP, Mondellini GM, Mattace-Raso AM, et al
    Immediate changes in Left Ventricular Cardiac Mechanics following Transcatheter Aortic Valve Replacement for Severe Aortic Stenosis - an In-Vivo Pressure-Volume Analysis study.
    Am Heart J. 2025 Nov 13:107302. doi: 10.1016/j.ahj.2025.107302.
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  48. MONTALESCOT G, Bolognese L, Bartus S, Cequier-Fillat A, et al
    Evolocumab Before Percutaneous Coronary Intervention for Acute Myocardial Infarction: Design of the AMUNDSEN Trial.
    Am Heart J. 2025 Nov 3:107295. doi: 10.1016/j.ahj.2025.107295.
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  49. MAHMOUDI M, Nicholas Z, Jabbour RJ, Shambrook J, et al
    Anatomical, physiological and inflammatory characterization of non-culprit vessels in patients undergoing primary PCI for ST-elevation myocardial infarction in the presence of multivessel disease: Rationale and design of the PICNIC study.
    Am Heart J. 2025 Nov 3:107298. doi: 10.1016/j.ahj.2025.107298.
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    October 2025
  50. OVERDUIN DC, van Ginkel DJ, Dubois C, Lesizza P, et al
    Routine versus selective protamine administration to reduce bleeding after TAVI: Rationale and Design of the POPular ACE TAVI trial.
    Am Heart J. 2025 Oct 31:107296. doi: 10.1016/j.ahj.2025.107296.
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  51. IGLESIAS JF, Leibundgut G, Heg D, Gasparini GL, et al
    Distal versus conventional radial large-bore access for percutaneous coronary intervention of complex coronary lesions: Rationale and design of the DISCO COMPLEX randomized superiority trial.
    Am Heart J. 2025 Oct 18:107291. doi: 10.1016/j.ahj.2025.107291.
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  52. ABDELAZIZ A, Ramadan S, Hasan MT, Desouky M, et al
    Complete Revascularization in Patients with Acute Myocardial Infarction and Multivessel Disease: Pooled Analysis of Kaplan-Meier-Derived Individual-Patient-Data.
    Am Heart J. 2025 Oct 2:107284. doi: 10.1016/j.ahj.2025.107284.
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  53. LEOSDOTTIR M, Dahlbom L, Back M, Wallentin L, et al
    Data quality assessment in the SWEDEHEART registry: Insights from serial audits on completeness and accuracy.
    Am Heart J. 2025;288:149-158.
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    September 2025
  54. FEISTRITZER HJ, Jobs A, Zeymer U, Schneider S, et al
    Complete revascularization versus culprit-lesion only PCI in patients with NSTEMI and multivessel disease - Design and rationale of the randomized COMPLETE-NSTEMI trial.
    Am Heart J. 2025;287:94-106.
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    July 2025
  55. REINSTADLER SJ, Kronbichler A, Reindl M, Tiller C, et al
    Selective C-reactive protein apheresis in ST-elevation myocardial infarction: Design and rationale of the randomized CRP-STEMI trial.
    Am Heart J. 2025 Jul 28:S0002-8703(25)00283-2. doi: 10.1016/j.ahj.2025.
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  56. HAN M, Kang J, Kim B, Hwang D, et al
    The impact of body mass index (BMI) on antiplatelet monotherapy strategy for secondary prevention after percutaneous coronary intervention: A sub-study of the HOST-EXAM trial.
    Am Heart J. 2025 Jul 5:S0002-8703(25)00214-5. doi: 10.1016/j.ahj.2025.
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  57. PITARO N, Nicolas J, Sartori S, Shneyderman M, et al
    Impact of Left Ventricular Function on Outcomes in Patients with Chronic Kidney Disease Undergoing Percutaneous Coronary Intervention.
    Am Heart J. 2025 Jul 1:S0002-8703(25)00203-0. doi: 10.1016/j.ahj.2025.
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    June 2025
  58. CUTLIP DE, Mehran R, Doros G, Kaplinskiy V, et al
    Prospective randomized single-blind multicenter study to assess the safety and effectiveness of the SELUTION SLR 014 drug eluting balloon in the treatment of subjects with in-stent restenosis: Rationale and design.
    Am Heart J. 2025;284:11-19.
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    May 2025
  59. GENG Q, Ying Z, Zhenyan M, Renqiang Y, et al
    Long-term Prognostic Role of Persistent Microvascular Obstruction Determined by Cardiac Magnetic Resonance for ST-segment Elevation Myocardial Infarction.
    Am Heart J. 2025 May 29:S0002-8703(25)00187-5. doi: 10.1016/j.ahj.2025.
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  60. MAINI AS, Abu-Much A, Redfors B, Wollmuth JR, et al
    Outcomes Among Patients with Coronary Bifurcation Lesions Undergoing Impella-Supported High-Risk Percutaneous Coronary Intervention.
    Am Heart J. 2025 May 22:S0002-8703(25)00176-0. doi: 10.1016/j.ahj.2025.
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  61. WHITE HD, O'Brien SM, Boden WE, Fremes SE, et al
    Use of Coronary Artery Bypass Graft Surgery and Percutaneous Coronary Intervention and Associated Outcomes in the ISCHEMIA Trial.
    Am Heart J. 2025 May 20:S0002-8703(25)00165-6. doi: 10.1016/j.ahj.2025.
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  62. MESSINGER MC, Ashburn NP, Chait JS, Snavely AC, et al
    Risk of delayed percutaneous coronary intervention for STEMI in the Southeast United States.
    Am Heart J. 2025 May 13:S0002-8703(25)00157-7. doi: 10.1016/j.ahj.2025.
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  63. KANDZARI DE, Latib A, Mylotte D, Ali ZA, et al
    Rationale and design of the prevail global trial program evaluating the prevail drug-coated balloon in patients with in-stent restenosis and de novo small vessel disease.
    Am Heart J. 2025;283:26-36.
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    April 2025
  64. HAKEEM A, Ali Shah J, Kumar R, Khan K, et al
    Rationale and Design of the TADCLOT Trial: A Double Blind Randomized Controlled Trial Comparing Twice a Day Clopidogrel vs. Ticagrelor in Reducing Major Cardiac Events in Patients with Acute STEMI Undergoing Primary Percutaneous Coronary Intervention.
    Am Heart J. 2025 Apr 12:S0002-8703(25)00103-6. doi: 10.1016/j.ahj.2025.
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  65. SOMSEN YBO, de Winter RW, Wu J, Hoek R, et al
    Design and rationale of the drug-coated balloon coronary angioplasty versus stenting for treatment of disease adjacent to a chronic total occlusion (Co-CTO) trial.
    Am Heart J. 2025 Apr 7:S0002-8703(25)00105-X. doi: 10.1016/j.ahj.2025.
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  66. COSSETTE F, Trifan A, Prevost-Marcotte G, Doolub G, et al
    Tailored hydration for the prevention of contrast-induced acute kidney injury after coronary angiogram or PCI: A systematic review and meta-analysis.
    Am Heart J. 2025;282:93-102.
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    March 2025
  67. ROSOVSKY RP, Konstantinides SV, Moriarty JM, Dohad SY, et al
    A prospective, multicenter, randomized controlled trial evaluating anticoagulation alone vs anticoagulation plus computer assisted vacuum thrombectomy for the treatment of intermediate-high-risk acute pulmonary embolism: Rationale and design of the ST
    Am Heart J. 2025 Mar 31:S0002-8703(25)00100-0. doi: 10.1016/j.ahj.2025.
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  68. HOFMANN R, James S, Sundqvist MO, Warme J, et al
    HELicobacter Pylori screening to prevent gastrointestinal bleeding in patients with acute Myocardial Infarction(HELP-MI SWEDEHEART)Design and rationale of a cluster randomized, crossover, registry-based clinical trial.
    Am Heart J. 2025 Mar 27:S0002-8703(25)00096-1. doi: 10.1016/j.ahj.2025.
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  69. ZEYMER U, Hassinger F, Bramlage P, Schafer A, et al
    Hyperoxemic Oxygen Therapy in Patients with Acute Anterior Myocardial Infarction: HOT-AAMI - Design and Rationale of a Randomized Trial.
    Am Heart J. 2025 Mar 21:S0002-8703(25)00095-X. doi: 10.1016/j.ahj.2025.
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  70. SISTA AK, Troxel AB, Tarpey T, Parpia S, et al
    Rationale and design of the PE-TRACT trial: A multicenter randomized trial to evaluate catheter-directed therapy for the treatment of intermediate-risk pulmonary embolism.
    Am Heart J. 2025;281:112-122.
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    February 2025
  71. JACOBSEN MR, Jabbari R, Grove EL, Maeng M, et al
    Genotype-guided de-escalation and abbreviation of dual antiplatelet therapy in patients with myocardial infarction and high bleeding risk: Design and rationale of the investigator-initiated, multicenter, randomized, controlled trial, DAN-DAPT.
    Am Heart J. 2025 Feb 25:S0002-8703(25)00059-6. doi: 10.1016/j.ahj.2025.
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  72. CHATUR S, Seth M, Casey M, Thompson M, et al
    Reminders EMbedded IN PCI Reports to Optimize Discharge Diabetes Mellitus Care (REMIND-DM): Rationale, Design, and Baseline Characteristics.
    Am Heart J. 2025 Feb 21:S0002-8703(25)00019-5. doi: 10.1016/j.ahj.2025.
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  73. ERRIQUEZ A, Colaiori I, Hakeem A, Guiducci V, et al
    Functional Coronary Angiography to Indicate and Guide Revascularization in STEMI Patients with Multivessel Disease: Rationale and Design of the AIR-STEMI trial: Functional coronary angiography in STEMI patients.
    Am Heart J. 2025 Feb 19:S0002-8703(25)00042-0. doi: 10.1016/j.ahj.2025.
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  74. BAINEY KR, Welsh RC, Zheng Y, Arias-Mendoza A, et al
    Pharmaco-invasive Strategy and Dosing of Tenecteplase in STEMI Patients 60 to <75 Years: An Inter-trial Comparison of the STREAM-1 and STREAM-2 Trials: Comparison of Patients 60 to <75 Years in STREAM-1 and -2.
    Am Heart J. 2025 Feb 12:S0002-8703(25)00032-8. doi: 10.1016/j.ahj.2025.
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  75. GAO XF, Kan J, Wu HY, Chen J, et al
    Intravascular Imaging-guided versus Angiography-guided Percutaneous Coronary Intervention in Patients with Diabetes Mellitus: Rationale and design of an International, Multicenter, Randomized IVI-DIABETES Trial.
    Am Heart J. 2025 Feb 4:S0002-8703(25)00017-1. doi: 10.1016/j.ahj.2025.
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  76. WANG G, Zhang R, Chen SL, Wang J, et al
    Targeted Therapy with a Localized abluminal Groove Low-Dose Sirolimus-Eluting Bioabsorbable Polymer Coronary Stent in Chronic Total Occlusions: The TARGET CTO Non-Inferiority Randomized Trial.
    Am Heart J. 2025 Feb 3:S0002-8703(25)00018-3. doi: 10.1016/j.ahj.2025.
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    January 2025
  77. STEG PG, Nicolas J, Baber U, Sartori S, et al
    Characterizing High-Risk Enrollment Criteria and Impact on Clinical Outcomes in a Large Randomized Clinical Trial: Insights From the TWILIGHT Trial.
    Am Heart J. 2025 Jan 29:S0002-8703(25)00016-X. doi: 10.1016/j.ahj.2025.
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  78. EFTEKHARI A, Christiansen EH, Lassen JF, Raungaard B, et al
    Randomized comparison of the combined Sirolimus eluting and endothelial progenitor cell Combo(TM) stent vs. Biolimus eluting absorbable polymer coated BioMatrix Alpha(TM) stent in patients undergoing percutaneous coronary intervention. Rationale and s
    Am Heart J. 2025 Jan 25:S0002-8703(25)00013-4. doi: 10.1016/j.ahj.2025.
    >> Share

  79. VELDTMAN GR, Abualsaud A, Cohen S, Ordonez MV, et al
    Fontan circulation and systemic disease - a retrospective cohort analysis over 35 years of follow-up.
    Am Heart J. 2025;279:40-49.
    >> Share

  80. YAN S, Jiang F, Sun Y, Wang Y, et al
    Methylprednisolone for acute type A aortic dissection patients undergoing total arch replacement: Design and rationale of the Medal trial.
    Am Heart J. 2025;279:20-26.
    >> Share

    December 2024
  81. CARULLI E, McGarvey M, Chabok M, Panoulas V, et al
    Transcoronary cooling and dilution for cardioprotection during revascularisation for ST-segment elevation myocardial infarction: design and rationale of the STEMI-Cool study.
    Am Heart J. 2024 Dec 30:S0002-8703(24)00338-7. doi: 10.1016/j.ahj.2024.
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  82. XU L, Xu H, Wu S, Zhang H, et al
    Indobufen-based Dual Antiplatelet Therapy in Patients with Multivessel Coronary Disease Undergoing Drug-eluting Stent Implantation Insight From the OPTION Trial.
    Am Heart J. 2024 Dec 20:S0002-8703(24)00335-1. doi: 10.1016/j.ahj.2024.
    >> Share

  83. CASSESE S, Simonetti F, Covarrubias HAA, Janisch M, et al
    Intracoronary Stenting and Additional Results Achieved by ShockWAVE Coronary Lithotripsy: Design and Rationale of ISAR-WAVE Trial.
    Am Heart J. 2024 Dec 20:S0002-8703(24)00337-5. doi: 10.1016/j.ahj.2024.
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  84. POLLACK LM, Chang A, Thompson MP, Keteyian SJ, et al
    Hospital-level variation in cardiac rehabilitation metrics.
    Am Heart J. 2024 Dec 13:S0002-8703(24)00333-8. doi: 10.1016/j.ahj.2024.
    >> Share

  85. AARTS HM, Hemelrijk KI, Broeze GM, van Ginkel DJ, et al
    Deferral of routine percutaneous coronary intervention in patients undergoing transcatheter aortic valve implantation: rationale and design of the PRO-TAVI trial: the PRO-TAVI trial: rationale and design.
    Am Heart J. 2024 Dec 12:S0002-8703(24)00332-6. doi: 10.1016/j.ahj.2024.
    >> Share

    November 2024
  86. FANAROFF AC, Vora AN, Wojdyla DM, Mehran R, et al
    Effect of apixaban versus vitamin K antagonist and aspirin versus placebo on days alive and out of hospital: An analysis from AUGUSTUS.
    Am Heart J. 2024 Nov 16:S0002-8703(24)00297-7. doi: 10.1016/j.ahj.2024.
    >> Share

  87. ABRAMOWITZ SD, Marko X, D'Souza D, Noor S, et al
    Rationale and Design of the DEFIANCE Study: A Randomized Controlled Trial of Mechanical Thrombectomy Versus Anticoagulation Alone for Iliofemoral Deep Vein Thrombosis.
    Am Heart J. 2024 Nov 2:S0002-8703(24)00278-3. doi: 10.1016/j.ahj.2024.
    >> Share

  88. ERLINGE D, Andersson J, Frobert O, Tornerud M, et al
    Rationale and design of INFINITY-SWEDEHEART: A registry-based randomized clinical trial comparing clinical outcomes of the sirolimus-eluting DynamX bioadaptor to the zotarolimus-eluting Resolute Onyx stent.
    Am Heart J. 2024;277:1-10.
    >> Share

    October 2024
  89. BARONE-ROCHETTE G, Vanzetto G, Danchin N, Steg PG, et al
    Rationale and design of the multicentric randomized EVAOLD trial: evaluation of a strategy guided by imaging versus routine invasive strategy in elderly patients with ischemia.
    Am Heart J. 2024 Oct 22:S0002-8703(24)00274-6. doi: 10.1016/j.ahj.2024.
    >> Share

  90. SAITO T, Kuno T, Fujisaki T, Gupta R, et al
    Dual antiplatelet therapy duration and stent type in patients with high bleeding risk: A systematic review and network meta-analysis.
    Am Heart J. 2024 Oct 5:S0002-8703(24)00266-7. doi: 10.1016/j.ahj.2024.
    >> Share

    September 2024
  91. DE COCK E, Kautbally S, Timmermans F, Bogaerts K, et al
    Low-dose colchicine for the prevention of cardiovascular events after percutaneous coronary intervention: rationale and design of the COL BE PCI trial: Short title: Rationale and design of the COL BE PCI trial.
    Am Heart J. 2024 Sep 2:S0002-8703(24)00225-4. doi: 10.1016/j.ahj.2024.
    >> Share

    August 2024
  92. VOGEL B, Jou S, Sartori S, Farhan S, et al
    Impact of sex on outcomes associated with polyvascular disease in patients after PCI.
    Am Heart J. 2024 Aug 7:S0002-8703(24)00196-0. doi: 10.1016/j.ahj.2024.
    >> Share

  93. AIHARA K, Torii S, Nakamura N, Hozumi H, et al
    Pathological Evaluation of Predictors for Delayed Endothelial Coverage After Currently Available Drug-eluting Stent Implantation in Coronary Arteries: Impact of Lesions With Acute and Chronic Coronary Syndromes.
    Am Heart J. 2024 Aug 7:S0002-8703(24)00197-2. doi: 10.1016/j.ahj.2024.
    >> Share

  94. STAHLI BE, Linke A, Westermann D, Van Mieghem NM, et al
    A Randomized Comparison of the Treatment Sequence of Percutaneous Coronary Intervention and Transcatheter Aortic Valve Implantation: Rationale and Design of the TAVI PCI Trial.
    Am Heart J. 2024 Aug 7:S0002-8703(24)00184-4. doi: 10.1016/j.ahj.2024.
    >> Share

    July 2024
  95. ERBAY A, Penzel L, Abdelwahed YS, Heuberger A, et al
    Prognostic impact of quantitative flow ratio (QFR)-consistent complete revascularization in patients with myocardial infarction and multivessel coronary artery disease.
    Am Heart J. 2024 Jul 19:S0002-8703(24)00177-7. doi: 10.1016/j.ahj.2024.
    >> Share

  96. YANG Y, Chu TC, Suthar D, Beshish AG, et al
    Association of patient-level characteristics with long-term outcomes after Fontan palliation: Rationale, design, and baseline characteristics of the Pediatric Cardiac Care Consortium Fontan cohort study.
    Am Heart J. 2024;273:111-120.
    >> Share

    June 2024
  97. JEYAPRAKASH P, Pathan F, Ozawa K, Robledo KP, et al
    Restoring microvascular circulation with diagnostic ultrasound and contrast agent: Rationale and Design of the REDUCE trial.
    Am Heart J. 2024 Jun 27:S0002-8703(24)00162-5. doi: 10.1016/j.ahj.2024.
    >> Share

  98. WU ZM, Kan J, Ye F, You W, et al
    PCSK9 Inhibitor Added to High-Intensity Statin Therapy to Prevent Cardiovascular Events in Patients with Acute Coronary Syndrome after Percutaneous Coronary Intervention: A Randomized, Double- Blind, Placebo-Controlled, Multicenter SHAWN Study.
    Am Heart J. 2024 Jun 26:S0002-8703(24)00157-1. doi: 10.1016/j.ahj.2024.
    >> Share

  99. D'ENTREMONT MA, Lee SF, Mian R, Kedev S, et al
    Design and Rationale of the CLEAR SYNERGY (OASIS 9) Trial: A 2x2 Factorial Randomized Controlled Trial of Colchicine versus placebo and Spironolactone versus placebo in Patients with Myocardial Infarction.
    Am Heart J. 2024 Jun 25:S0002-8703(24)00161-3. doi: 10.1016/j.ahj.2024.
    >> Share

  100. SONG L, Guan C, Yu M, Sun Z, et al
    Sirolimus-eluting iron bioresorbable scaffold versus cobalt-chromium everolimus-eluting stents in patients with coronary artery disease: rationale and design of the IRONMAN-II trial.
    Am Heart J. 2024 Jun 3:S0002-8703(24)00140-6. doi: 10.1016/j.ahj.2024.
    >> Share

  101. ZHANG RS, Maqsood MH, Greco AA, Postelnicu R, et al
    Efficacy and safety of catheter-based thrombectomy versus catheter-directed thrombolysis in acute pulmonary embolism.
    Am Heart J. 2024;272:109-112.
    >> Share

    May 2024
  102. KIM Y, Park H, Yoon HJ, Suh J, et al
    Fully Automated Quantitative Coronary Angiography Versus Optical Coherence Tomography Guidance for Coronary Stent Implantation (FLASH): Study Protocol for a Randomized Controlled Non-Inferiority Trial.
    Am Heart J. 2024 May 7:S0002-8703(24)00119-4. doi: 10.1016/j.ahj.2024.
    >> Share

  103. ZHANG F, Tian M, Wang X, Zhang H, et al
    Rationale and design of a Single-center Randomized Trial to Compare the Graft Patency between the Radial Artery and the No-touch Saphenous Vein in Coronary Artery Bypass Grafting Surgery (GRAFT-CAB Study).
    Am Heart J. 2024 May 4:S0002-8703(24)00117-0. doi: 10.1016/j.ahj.2024.
    >> Share

  104. LEMLEY BA, Okunowo O, Ampah SB, Wu L, et al
    Effect of patient factors, center, and era on Fontan timing: An observational study using the Pediatric Health Information Systems Database.
    Am Heart J. 2024;271:156-163.
    >> Share

    April 2024
  105. KIM MC, Ahn JH, Hyun DY, Lim Y, et al
    Timing of fractional flow reserve-guided complete revascularization in patients with ST-segment elevation myocardial infarction with multivessel disease: Rationale and design of the OPTION-STEMI trial.
    Am Heart J. 2024 Apr 17:S0002-8703(24)00078-4. doi: 10.1016/j.ahj.2024.
    >> Share

  106. WEGERIF ECJ, Unlu C, Generaal MI, van den Bor R, et al
    Rationale and design for the randomized placebo-controlled double-blind trial studying the effect of single antiplatelet therapy (clopidogrel) versus dual antiplatelet therapy (clopidogrel/acetylsalicylic acid) on the occurrence of atherothrombotic ev
    Am Heart J. 2024 Apr 10:S0002-8703(24)00080-2. doi: 10.1016/j.ahj.2024.
    >> Share

    March 2024
  107. KRUCOFF M, Spirito A, Baber U, Sartori S, et al
    Ticagrelor With or Without Aspirin Following Percutaneous Coronary Intervention in High-Risk Patients With Concomitant Peripheral Artery Disease: a subgroup analysis of the TWILIGHT randomized clinical trial.
    Am Heart J. 2024 Mar 6:S0002-8703(24)00053-X. doi: 10.1016/j.ahj.2024.
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    February 2024
  108. MEHDIPOOR G, Redfors B, Chen S, Gkargkoulas F, et al
    Hypertension, Microvascular Obstruction and Infarct Size in Patients with STEMI Undergoing PCI: Pooled Analysis from 7 Cardiac Magnetic Resonance Imaging Studies.
    Am Heart J. 2024 Feb 29:S0002-8703(24)00050-4. doi: 10.1016/j.ahj.2024.
    >> Share

  109. LEE SH, Lee SJ, Heo JH, Ahn SG, et al
    Optimal antithrombotic strategy in patients with atrial fibrillation beyond 1 year after drug-eluting stent implantation: Design and rationale of the randomized ADAPT AF-DES trial.
    Am Heart J. 2024 Feb 22:S0002-8703(24)00041-3. doi: 10.1016/j.ahj.2024.
    >> Share

  110. DEHGHANI P, Singh J, Mancini GBJ, Stanberry L, et al
    Angiographic characteristics of Patients with STEMI and COVID-19 - Insights from NACMI Registry.
    Am Heart J. 2024 Feb 21:S0002-8703(24)00039-5. doi: 10.1016/j.ahj.2024.
    >> Share

  111. KEDHI E, Rroku A, Hermanides RS, Dambrink JH, et al
    TransCatheter Aortic Valve Implantation and Fractional Flow Reserve-Guided Percutaneous Coronary Intervention versus Conventional Surgical Aortic Valve Replacement and Coronary Bypass Grafting for Treatment of Patients with Aortic Valve Stenosis and M
    Am Heart J. 2024 Feb 1:S0002-8703(24)00019-X. doi: 10.1016/j.ahj.2024.
    >> Share

    January 2024
  112. ASHWAT E, Brown JA, Yousef S, Ahmad D, et al
    Radial Artery versus Right Internal Mammary Artery as a Second Conduit during Coronary Artery Bypass Grafting.
    Am Heart J. 2024 Jan 20:S0002-8703(24)00015-2. doi: 10.1016/j.ahj.2024.
    >> Share

  113. ALVIAR CL, Li BK, Keller NM, Bohula-May E, et al
    Prognostic Performance of the IABP-SHOCK II Risk Score Among Cardiogenic Shock Subtypes in the Critical Care Cardiology Trials Network Registry.
    Am Heart J. 2024 Jan 6:S0002-8703(23)00361-7. doi: 10.1016/j.ahj.2023.
    >> Share

  114. ZHANG RS, Ho AM, Elbaum L, Greco AA, et al
    Quality and rapidity of anticoagulation in patients with acute pulmonary embolism undergoing mechanical thrombectomy.
    Am Heart J. 2024;267:91-94.
    >> Share

    December 2023
  115. ABU-MUCH A, Grines CL, Batchelor WB, Maini AS, et al
    Influence of Left Ventricular Ejection Fraction in Patients Undergoing Contemporary pLVAD-Supported High-Risk PCI.
    Am Heart J. 2023 Dec 25:S0002-8703(23)00358-7. doi: 10.1016/j.ahj.2023.
    >> Share

  116. SIREN M, Leivo J, Anttonen E, Jolly SS, et al
    The Prognostic Significance of Single-Lead ST-Segment Resolution in ST-Segment Elevation Myocardial Infarction Patients Treated with Primary PCI - A Substudy of the Randomized TOTAL Trial.
    Am Heart J. 2023 Dec 16:S0002-8703(23)00347-2. doi: 10.1016/j.ahj.2023.
    >> Share

  117. KANTHASAMY V, Schilling R, Zongo O, Khan K, et al
    Feasibility of Double-Blinded, Placebo-Controlled Interventional Study for Assessing Catheter Ablation Efficacy in Persistent Atrial Fibrillation: Insights from the ORBITA AF Feasibility study.
    Am Heart J. 2023 Dec 16:S0002-8703(23)00353-8. doi: 10.1016/j.ahj.2023.
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  118. DILLEN DMM, Vlaar PJ, Vermeer AJE, Paradies V, et al
    Bifurcation PCI with a hybrid strategy with drug- eluting balloons versus a stepwise provisional two- stent strategy: Rationale and design of the hybrid DEB study.
    Am Heart J. 2023;266:168-175.
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    November 2023
  119. MUNHOZ D, Collet C, Mizukami T, Yong A, et al
    Rationale and design of the pullback pressure gradient (PPG) global registry.
    Am Heart J. 2023;265:170-179.
    >> Share

  120. DELMAS C, Laine M, Schurtz G, Roubille F, et al
    Rationale and design of the ULYSS trial: A randomized multicenter evaluation of the efficacy of early Impella CP implantation in acute coronary syndrome complicated by cardiogenic shock.
    Am Heart J. 2023;265:203-212.
    >> Share

    October 2023
  121. BAINEY KR, Wood DA, Bossard M, Campo G, et al
    Effects of Complete Revascularization According to Age in Patients with ST-Segment Elevation Myocardial Infarction and Multivessel Disease (COMPLETE-AGE).
    Am Heart J. 2023 Oct 21:S0002-8703(23)00297-1. doi: 10.1016/j.ahj.2023.
    >> Share

    September 2023
  122. PUYMIRAT E, Soulat G, Fayol A, Mousseaux E, et al
    Rationale and Design of the Direct Oral Anticoagulants for Prevention of Left Ventricular Thrombus after Anterior Acute Myocardial Infarction (APERITIF) trial.
    Am Heart J. 2023 Sep 14:S0002-8703(23)00278-8. doi: 10.1016/j.ahj.2023.
    >> Share

  123. GONSALVES CF, Gibson CM, Stortecky S, Alvarez RA, et al
    Randomized Controlled Trial of Mechanical Thrombectomy Versus Catheter-directed Thrombolysis for Acute Hemodynamically Stable Pulmonary Embolism: Rationale and Design of the PEERLESS Study.
    Am Heart J. 2023 Sep 11:S0002-8703(23)00274-0. doi: 10.1016/j.ahj.2023.
    >> Share

    August 2023
  124. DODGSON CAS, Beitnes JO, Klove SF, Herstad J, et al
    An investigator-sponsored pragmatic randomised controlled trial of AntiCoagulation versus AcetylSalicylic Acid after Transcatheter Aortic Valve Implantation - Rationale and design of ACASA-TAVI: Blinded outcome adjudication.
    Am Heart J. 2023 Aug 25:S0002-8703(23)00208-9. doi: 10.1016/j.ahj.2023.
    >> Share

  125. PICCOLO R, Calabro P, Varricchio A, Baldi C, et al
    Rationale and Design of the PARTHENOPE Trial: A Two-by-Two Factorial Comparison of Polymer-Free vs. Biodegradable-Polymer Drug-Eluting Stents and Personalized vs. Standard Duration of Dual Antiplatelet Therapy in All-Comers Undergoing PCI.
    Am Heart J. 2023 Aug 10:S0002-8703(23)00188-6. doi: 10.1016/j.ahj.2023.
    >> Share

    July 2023
  126. VAN DER SANGEN NMR, Kucuk IT, Sivanesan S, Appelman Y, et al
    Less Bleeding by Omitting Aspirin in Non-ST-segment Elevation Acute Coronary Syndrome Patients: Rationale and Design of the LEGACY study.
    Am Heart J. 2023 Jul 28:S0002-8703(23)00183-7. doi: 10.1016/j.ahj.2023.
    >> Share

  127. PARK S, Rha SW, Choi BG, Kim W, et al
    Efficacy and Safety of Cilostazol-Based Triple Antiplatelet Therapy Compared with Clopidogrel-Based Dual Antiplatelet Therapy in Patients with Acute ST-Elevation Myocardial Infarction Undergoing Percutaneous Coronary Intervention: A Multicenter, Rando
    Am Heart J. 2023 Jul 3:S0002-8703(23)00172-2. doi: 10.1016/j.ahj.2023.
    >> Share

    June 2023
  128. LI C, Eikelboom JW, Zhong Z, Zhang X, et al
    Efficacy and safety of a bolus of half-dose r-SAK prior to primary PCI in ST-elevation myocardial infarction: Rationale and design of the OPTIMA-6 trial.
    Am Heart J. 2023 Jun 25:S0002-8703(23)00168-0. doi: 10.1016/j.ahj.2023.
    >> Share

  129. BUJAK K, Vidal-Cales P, Gabani R, Rinaldi R, et al
    Relationship between stent length and very long-term target lesion failure following percutaneous coronary intervention for ST-elevation myocardial infarction in the drug-eluting stents era: insights from the EXAMINATION-EXTEND study.
    Am Heart J. 2023 Jun 4:S0002-8703(23)00141-2. doi: 10.1016/j.ahj.2023.
    >> Share

  130. AHN JM, Kang DY, Lee PH, Ahn YK, et al
    Preventive PCI or Medical Therapy Alone for Vulnerable Atherosclerotic Coronary Plaque: Rationale and Design of the Randomized, Controlled PREVENT Trial.
    Am Heart J. 2023 Jun 2:S0002-8703(23)00134-5. doi: 10.1016/j.ahj.2023.
    >> Share


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