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Articles published in
Nat Immunol
    June 2026

  1. Diversifying the antibody response to influenza virus with an mRNA-based vaccine.
    Nat Immunol. 2026 Jun 23. doi: 10.1038/s41590-026-02565.
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  2. HAUPT S, Cottrell CA, Zhou X, Lee JH, et al
    Rapid boosting increases germinal center responses to sequential vaccines.
    Nat Immunol. 2026 Jun 23. doi: 10.1038/s41590-026-02549.
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  3. WANG B, Chen L, Tagliabue A, Ulmer J, et al
    From vaccinology to immunology and back: progress and challenges.
    Nat Immunol. 2026 Jun 22. doi: 10.1038/s41590-026-02543.
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  4. MATZ HC, Yu TG, Dixit K, Kikawa C, et al
    mRNA-based influenza vaccine expands the B cell response breadth in humans.
    Nat Immunol. 2026 Jun 15. doi: 10.1038/s41590-026-02569.
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  5. AGRAWAL N, Ates LS, Schille SA, Chaturvedi A, et al
    mRNA-based tuberculosis vaccines BNT164a1 and BNT164b1 are immunogenic, well tolerated and efficacious in rodent models.
    Nat Immunol. 2026 Jun 12. doi: 10.1038/s41590-026-02545.
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  6. CHEN G, Guo J, Heath J, Prestwood TR, et al
    Human vaccine responses regulated by parallel cytokine pathways.
    Nat Immunol. 2026 Jun 12. doi: 10.1038/s41590-026-02547.
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  7. SARAIVA M, Branchett WJ, Rengarajan J, O'Garra A, et al
    The host immune response to Mycobacterium tuberculosis determining protection or disease progression.
    Nat Immunol. 2026;27:1104-1118.
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  8. KELCHTERMANS L, Geerts K, Pham CT, Malviya V, et al
    CD4(+) T cell-mediated immunity protects from VSV-SUD lethal challenge in a mouse model of Sudan virus infection.
    Nat Immunol. 2026;27:1224-1236.
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    May 2026

  9. Fungal glycans boost mRNA-based vaccines.
    Nat Immunol. 2026 May 25. doi: 10.1038/s41590-026-02522.
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  10. JENA KK, Qu P, Baracco L, Saghaei S, et al
    A glycan-based adjuvant expands the breadth and duration of protection of mRNA-based vaccines.
    Nat Immunol. 2026 May 22. doi: 10.1038/s41590-026-02517.
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  11. PECETTA S, Andreano E, Rappuoli R
    Broadly protective mucosal vaccination in the respiratory tract.
    Nat Immunol. 2026 May 19. doi: 10.1038/s41590-026-02530.
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    April 2026
  12. JENKINS RG
    Developing a vaccine strategy to prevent the progression of pulmonary fibrosis.
    Nat Immunol. 2026 Apr 20. doi: 10.1038/s41590-026-02487.
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  13. CHAULAGAIN S, Liu JA, McCombs JE, Klein SL, et al
    Sex differences in immune responses to viruses, bacteria and vaccines.
    Nat Immunol. 2026;27:660-673.
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    March 2026
  14. KHURANA S, Posadas O, Kardava L, Coyle EM, et al
    Improved VSV-Ebola-GP booster vaccination approach promotes antibody affinity maturation and durable anti-Ebola immunity in humans.
    Nat Immunol. 2026 Mar 19. doi: 10.1038/s41590-026-02459.
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  15. RELANO-RODRIGUEZ I, Du J, Lin ZJ, Kerwin M, et al
    Rapid elicitation of neutralizing Asn332-glycan-independent antibodies to the V3-glycan epitope of HIV-1 Env in nonhuman primates.
    Nat Immunol. 2026;27:586-599.
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  16. FRISCHHOLZ S, Schuster EM, Grotz M, Schulein C, et al
    Metabolic quiescence of naive-like memory T cells precedes and maintains antigen-specific T cell memory.
    Nat Immunol. 2026;27:452-462.
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  17. GIESELMANN L, DeLaitsch AT, Rohde M, Radford C, et al
    Identification of a potent V3 glycan site broadly neutralizing antibody targeting an N332(gp120) glycan-independent epitope.
    Nat Immunol. 2026;27:572-585.
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    February 2026
  18. BLANCO J
    Better and closer glycan-independent anti-V3 antibodies to help HIV-1 vaccine.
    Nat Immunol. 2026 Feb 3. doi: 10.1038/s41590-025-02409.
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    January 2026
  19. FANG C, Esposito M, Hars U, Byrne RT, et al
    Targeting autocrine retinoic acid signaling by ALDH1A2 inhibition enhances antitumor dendritic cell vaccine efficacy.
    Nat Immunol. 2026 Jan 5. doi: 10.1038/s41590-025-02376.
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    October 2025
  20. KHLEIF SN, Gupta S
    Cancer vaccines as enablers of immunotherapy.
    Nat Immunol. 2025 Oct 16. doi: 10.1038/s41590-025-02308.
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  21. AKHTAR A, Styles TM, Gu C, Leon AN, et al
    Influenza vaccine based on AS03-adjuvanted chimeric HA induces long-lived stalk-specific plasma cells in bone marrow and lymph nodes of nonhuman primates.
    Nat Immunol. 2025 Oct 15. doi: 10.1038/s41590-025-02309.
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    June 2025
  22. QUIRK GE, Schoenle MV, Peyton KL, Uhrlaub JL, et al
    Intrinsic immunogenicity is a major determinant of type-specific responses in SARS-CoV-2 infections.
    Nat Immunol. 2025;26:829-836.
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    May 2025
  23. FENG Y, Pulendran B
    Antibiotics, microbiota and the calibration of infant vaccine responses.
    Nat Immunol. 2025 May 19. doi: 10.1038/s41590-025-02169.
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  24. KWON DI, Mao T, Israelow B, Santos Guedes de Sa K, et al
    Mucosal unadjuvanted booster vaccines elicit local IgA responses by conversion of pre-existing immunity in mice.
    Nat Immunol. 2025 May 13. doi: 10.1038/s41590-025-02156.
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    January 2025
  25. WALSH JML, Miao VN, Owings AH, Tang Y, et al
    Variants and vaccines impact nasal immunity over three waves of SARS-CoV-2.
    Nat Immunol. 2025 Jan 20. doi: 10.1038/s41590-024-02052.
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  26. CORTESE M, Hagan T, Rouphael N, Wu SY, et al
    System vaccinology analysis of predictors and mechanisms of antibody response durability to multiple vaccines in humans.
    Nat Immunol. 2025;26:116-130.
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  27. APOSTOLIDIS SA, Locci M
    SLE B cells take an extrafollicular detour after mRNA vaccination.
    Nat Immunol. 2025;26:4-6.
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    December 2024
  28. FALITI CE, Van TTP, Anam FA, Cheedarla N, et al
    Publisher Correction: Disease-associated B cells and immune endotypes shape adaptive immune responses to SARS-CoV-2 mRNA vaccination in human SLE.
    Nat Immunol. 2024 Dec 2. doi: 10.1038/s41590-024-02045.
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    November 2024
  29. FALITI CE, Van TTP, Anam FA, Cheedarla N, et al
    Disease-associated B cells and immune endotypes shape adaptive immune responses to SARS-CoV-2 mRNA vaccination in human SLE.
    Nat Immunol. 2024 Nov 12. doi: 10.1038/s41590-024-02010.
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    October 2024
  30. COBEY S
    Vaccination against rapidly evolving pathogens and the entanglements of memory.
    Nat Immunol. 2024 Oct 9. doi: 10.1038/s41590-024-01970.
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  31. JAUREGUI P
    Old and new mpox vaccine.
    Nat Immunol. 2024;25:1770.
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    September 2024
  32. JIAN F, Cao Y
    The delivery device of SARS-CoV-2 mucosal vaccine matters.
    Nat Immunol. 2024 Sep 3. doi: 10.1038/s41590-024-01950.
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  33. GAGNE M, Flynn BJ, Andrew SF, Marquez J, et al
    Mucosal adenovirus vaccine boosting elicits IgA and durably prevents XBB.1.16 infection in nonhuman primates.
    Nat Immunol. 2024 Sep 3. doi: 10.1038/s41590-024-01951.
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    August 2024
  34. BORCHERDING N, Kim W, Quinn M, Han F, et al
    CD4(+) T cells exhibit distinct transcriptional phenotypes in the lymph nodes and blood following mRNA vaccination in humans.
    Nat Immunol. 2024 Aug 20. doi: 10.1038/s41590-024-01888.
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  35. NELSON CS, Sage PT
    T(FH) cell responses endure in human lymph nodes after vaccination.
    Nat Immunol. 2024 Aug 20. doi: 10.1038/s41590-024-01935.
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  36. SCHATTGEN SA, Turner JS, Ghonim MA, Crawford JC, et al
    Influenza vaccination stimulates maturation of the human T follicular helper cell response.
    Nat Immunol. 2024 Aug 20. doi: 10.1038/s41590-024-01926.
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    June 2024

  37. Vaccination prevents cognitive impairment after breakthrough infection with SARS-CoV-2.
    Nat Immunol. 2024 Jun 25. doi: 10.1038/s41590-024-01869.
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  38. VANDERHEIDEN A, Hill JD, Jiang X, Deppen B, et al
    Vaccination reduces central nervous system IL-1beta and memory deficits after COVID-19 in mice.
    Nat Immunol. 2024 Jun 20. doi: 10.1038/s41590-024-01868.
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  39. SCHIFFNER T, Phung I, Ray R, Irimia A, et al
    Author Correction: Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
    Nat Immunol. 2024 Jun 14. doi: 10.1038/s41590-024-01891.
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  40. RAY R, Schiffner T, Wang X, Yan Y, et al
    Affinity gaps among B cells in germinal centers drive the selection of MPER precursors.
    Nat Immunol. 2024;25:1083-1096.
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    May 2024
  41. SCHIFFNER T, Phung I, Ray R, Irimia A, et al
    Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
    Nat Immunol. 2024 May 30. doi: 10.1038/s41590-024-01833.
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    March 2024
  42. FUMAGALLI V, Rava M, Marotta D, Di Lucia P, et al
    Antibody-independent protection against heterologous SARS-CoV-2 challenge conferred by prior infection or vaccination.
    Nat Immunol. 2024 Mar 14. doi: 10.1038/s41590-024-01787.
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  43. TRAN KA, Pernet E, Sadeghi M, Downey J, et al
    BCG immunization induces CX3CR1(hi) effector memory T cells to provide cross-protection via IFN-gamma-mediated trained immunity.
    Nat Immunol. 2024;25:418-431.
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    October 2023
  44. PAINTER MM, Johnston TS, Lundgreen KA, Santos JJS, et al
    Prior vaccination promotes early activation of memory T cells and enhances immune responses during SARS-CoV-2 breakthrough infection.
    Nat Immunol. 2023;24:1711-1724.
    >> Share


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