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Diseases of the Thyroid

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Articles published in
Clin Cancer Res
    May 2026
  1. LUONG QT, O'Kelly J, Braunstein GD, Hershman JM, et al
    Editor's Note: Antitumor Activity of Suberoylanilide Hydroxamic Acid against Thyroid Cancer Cell Lines In vitro and In vivo.
    Clin Cancer Res. 2026;32:1912.
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    April 2026
  2. KONG Z, Liu Y, Lin YS, Li Z, et al
    Covalent FAPI Imaging-Guided Precision Surgery in Patients with Medullary Thyroid Carcinoma: A Phase II Clinical Trial.
    Clin Cancer Res. 2026 Apr 21:OF1-OF11. doi: 10.1158/1078-0432.CCR-25-3970.
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  3. LI S, Wu CC, Marczyk VR, Loberg MA, et al
    PRECISE: A prognostic thyrocyte-derived gene signature for papillary thyroid carcinoma.
    Clin Cancer Res. 2026 Apr 20. doi: 10.1158/1078-0432.CCR-25-4488.
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  4. SHI F, Chai W, Yang H, Cao W, et al
    AL2846, a novel multi-kinase inhibitor, for previously treated radioiodine-refractory differentiated thyroid cancer: Exploratory clinical results from the phase Ib study.
    Clin Cancer Res. 2026 Apr 9. doi: 10.1158/1078-0432.CCR-25-3945.
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    February 2026
  5. LI JZ, Ricarte Filho J, Isaza AR, Hinkle K, et al
    DNA Methylation-based Risk Stratification and Classification of Pediatric Thyroid Carcinoma.
    Clin Cancer Res. 2026 Feb 17. doi: 10.1158/1078-0432.CCR-25-2109.
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    January 2026
  6. CHIRRA M, Elliott A, Shaikh H, McGrath J, et al
    Molecular Profiling and Real-World Outcomes of BRAF V600E-Mutated Papillary Thyroid Cancer.
    Clin Cancer Res. 2026 Jan 16. doi: 10.1158/1078-0432.CCR-25-3932.
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  7. JIANG L, Li X, Ma T, Zeng P, et al
    Clinical Significance for risk stratification of papillary thyroid cancer by TUMORFISHER circulating tumor cells technique.
    Clin Cancer Res. 2026 Jan 16. doi: 10.1158/1078-0432.CCR-25-2694.
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    September 2025
  8. SEHGAL K
    Personalized Thyroidology: Molecular Rewiring of Thyroid Nodule Management.
    Clin Cancer Res. 2025 Sep 26. doi: 10.1158/1078-0432.CCR-25-2474.
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    June 2025
  9. DING M, Wu G, Zhang S, Xie R, et al
    Clinical implications and application of molecular testing in the diagnosis and management of thyroid nodules in the Chinese population.
    Clin Cancer Res. 2025 Jun 27. doi: 10.1158/1078-0432.CCR-25-0270.
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  10. HARRISON C, Blake AK, Su Y, Tang L, et al
    Contribution of Germline Predisposition to Pediatric Thyroid Cancer.
    Clin Cancer Res. 2025 Jun 27. doi: 10.1158/1078-0432.CCR-25-0631.
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    March 2025
  11. LEE J, Shin Y, Kwak J, Park HL, et al
    Validation of Diagnostic Utility of Washout CYFRA 21-1 in Lymph Node Metastasis of Thyroid Cancer.
    Clin Cancer Res. 2025 Mar 12. doi: 10.1158/1078-0432.CCR-24-3562.
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    November 2024
  12. LI Q, Zhang W, Liao T, Gao Y, et al
    An AI-driven preoperative radiomic subtype for predicting the prognosis and treatment response of patients with papillary thyroid carcinoma.
    Clin Cancer Res. 2024 Nov 13. doi: 10.1158/1078-0432.CCR-24-2356.
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    June 2024
  13. FRENCH JD, Haugen BR, Worden FP, Bowles DW, et al
    Combination Targeted Therapy with Lenvatinib and Pembrolizumab in Progressive, Radioiodine-Refractory Differentiated Thyroid Cancers.
    Clin Cancer Res. 2024 Jun 26. doi: 10.1158/1078-0432.CCR-23-3417.
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    May 2024
  14. HEFT NEAL ME, Haring CT, Bellile E, Jaffe CC, et al
    Phase II Clinical Trial of Intravenous Levothyroxine to Mitigate Pharyngocutaneous Fistula in Euthyroid Patients Undergoing Salvage Laryngectomy.
    Clin Cancer Res. 2024 May 9. doi: 10.1158/1078-0432.CCR-24-0782.
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  15. PENG X, Zhao H, Ye L, Hou F, et al
    Biomarker identification and risk prediction model development for differentiated thyroid carcinoma lung metastasis based on primary lesion proteomics.
    Clin Cancer Res. 2024 May 9. doi: 10.1158/1078-0432.CCR-23-3806.
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    April 2024
  16. READ ML, Brookes K, Zha L, Manivannan S, et al
    Combined Vorinostat and Chloroquine Inhibit Sodium-Iodide Symporter Endocytosis and Enhance Radionuclide Uptake In Vivo.
    Clin Cancer Res. 2024;30:1352-1366.
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    January 2024
  17. LECHNER MG, Brent GA
    A New Twist on a Classic: Enhancing Radioiodine Uptake in Advanced Thyroid Cancer.
    Clin Cancer Res. 2024 Jan 10. doi: 10.1158/1078-0432.CCR-23-3503.
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    December 2023
  18. KIM YH, Yoon SJ, Kim M, Kim HH, et al
    Integrative multi-omics analysis reveals different metabolic phenotypes based on molecular characteristics in thyroid cancer.
    Clin Cancer Res. 2023 Dec 13. doi: 10.1158/1078-0432.CCR-23-2025.
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    November 2023
  19. SHEN C, Shi X, Wen D, Zhang Y, et al
    Comprehensive DNA Methylation Profiling of Medullary Thyroid Carcinoma: Molecular Classification, Potential Therapeutic Target, and Classifier System.
    Clin Cancer Res. 2023 Nov 6. doi: 10.1158/1078-0432.CCR-23-2142.
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    October 2023
  20. FU H, Huang J, Zhao T, Wang H, et al
    Fibroblast Activation Protein-Targeted Radioligand Therapy with 177Lu-EB-FAPI for Metastatic Radioiodine Refractory Thyroid Cancer: First-in-Human, Dose-Escalation Study.
    Clin Cancer Res. 2023 Oct 6. doi: 10.1158/1078-0432.CCR-23-1983.
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    September 2023
  21. DUKE ES, Bradford D, Marcovitz M, Amatya AK, et al
    FDA Approval Summary: Selpercatinib for the Treatment of Advanced RET Fusion-Positive Solid Tumors.
    Clin Cancer Res. 2023;29:3573-3578.
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    August 2023
  22. CHI Y, Zheng X, Zhang Y, Shi F, et al
    Anlotinib in Locally Advanced or Metastatic Radioiodine-Refractory Differentiated Thyroid Carcinoma: A Randomized, Double-Blind, Multicenter Phase â…¡ Trial.
    Clin Cancer Res. 2023 Aug 18:CCR-22-3406. doi: 10.1158/1078-0432.CCR-22-3406.
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    June 2023
  23. HU H, Ng TSC, Kang M, Scott E, et al
    Thyroid cancers exhibit oncogene-enhanced macropinocytosis that is restrained by IGF1R and promotes albumin-drug-conjugate response.
    Clin Cancer Res. 2023 Jun 8:CCR-22-2976. doi: 10.1158/1078-0432.CCR-22-2976.
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  24. BIKAS A, Ahmadi S, Pappa T, Marqusee E, et al
    Additional Oncogenic Alterations in RAS-Driven Differentiated Thyroid Cancers Associate with Worse Clinicopathologic Outcomes.
    Clin Cancer Res. 2023 Jun 1:OF1-OF8. doi: 10.1158/1078-0432.CCR-23-0278.
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    May 2023
  25. BIKAS A, Ahmadi S, Pappa T, Marqusee E, et al
    Additional Oncogenic Alterations in RAS-Driven Differentiated Thyroid Cancers Associate with Worse Clinicopathologic Outcomes.
    Clin Cancer Res. 2023 May 16:CCR-23-0278. doi: 10.1158/1078-0432.CCR-23-0278.
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  26. LIN Y, Qin S, Yang H, Shi F, et al
    Multicenter randomized double-blind phase III trial of donafenib in progressive radioactive iodine-refractory differentiated thyroid cancer.
    Clin Cancer Res. 2023 May 15:CCR-22-3613. doi: 10.1158/1078-0432.CCR-22-3613.
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    April 2023
  27. LEBOULLEUX S, Do Cao C, Zerdoud S, Attard M, et al
    A Phase II Redifferentiation Trial with Dabrafenib-Trametinib and 131I in Metastatic Radioactive Iodine Refractory BRAF p.V600E Mutated Differentiated thyroid Cancer.
    Clin Cancer Res. 2023 Apr 19:CCR-23-0046. doi: 10.1158/1078-0432.CCR-23-0046.
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