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Articles published in
J Clin Invest
    November 2021
  1. PERSAUD SP, Ritchey JK, Kim S, Lim S, et al
    Antibody-drug conjugates plus Janus kinase inhibitors enable MHC-mismatched allogeneic hematopoietic stem cell transplantation.
    J Clin Invest. 2021 Nov 2. pii: 145501. doi: 10.1172/JCI145501.
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    October 2021
  2. CHEN Z, Lu T, Huang L, Wang Z, et al
    Circular RNA cia-MAF drives self-renewal and metastasis of liver tumor-initiating cells via transcription factor MAFF.
    J Clin Invest. 2021;131.
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    August 2021
  3. CHEN Y, Fang S, Ding Q, Jiang R, et al
    ADGRG1 enriches for functional human hematopoietic stem cells following ex vivo expansion-induced mitochondrial oxidative stress.
    J Clin Invest. 2021 Aug 31. pii: e148329. doi: 10.1172/JCI148329.
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  4. QIAN J, LeSavage BL, Hubka KM, Ma C, et al
    Cancer-associated mesothelial cells promote ovarian cancer chemoresistance through paracrine osteopontin signaling.
    J Clin Invest. 2021;131.
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  5. WU K, Kamimoto K, Zhang Y, Yang K, et al
    Basal-epithelial stem cells cross an alarmin checkpoint for post-viral lung disease.
    J Clin Invest. 2021 Aug 10. pii: e149336. doi: 10.1172/JCI149336.
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    July 2021
  6. AHN JH, Kim J, Hong SP, Choi SY, et al
    Nasal ciliated cells are primary targets for SARS-CoV-2 replication in the early stage of COVID-19.
    J Clin Invest. 2021;131.
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    June 2021
  7. SHAIM H, Shanley M, Basar R, Daher M, et al
    Targeting the alphav integrin-TGF-beta axis improves natural killer cell function against glioblastoma stem cells.
    J Clin Invest. 2021 Jun 17. pii: e142116. doi: 10.1172/JCI142116.
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  8. TANG XY, Xu L, Wang J, Hong Y, et al
    DSCAM/PAK1 pathway suppression reverses neurogenesis deficits in iPSC-derived cerebral organoids from patients with Down syndrome.
    J Clin Invest. 2021;131.
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  9. SOCIE G, Kean LS, Zeiser R, Blazar BR, et al
    Insights from integrating clinical and preclinical studies advance understanding of graft-versus-host disease.
    J Clin Invest. 2021 Jun 8. pii: e149296. doi: 10.1172/JCI149296.
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  10. CARTER NM, Pomerantz JL
    Calcineurin inhibitors target Lck activation in graft-versus-host disease.
    J Clin Invest. 2021;131.
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  11. LOONG JH, Wong TL, Tong M, Sharma R, et al
    Glucose deprivation-induced aberrant FUT1-mediated fucosylation drives cancer stemness in hepatocellular carcinoma.
    J Clin Invest. 2021;131.
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    April 2021
  12. WANG L, Liu Y, Stratigopoulos G, Panigrahi S, et al
    Bardet-Biedl syndrome proteins regulate intracellular signaling and neuronal function in patient-specific iPSC-derived neurons.
    J Clin Invest. 2021;131.
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    March 2021
  13. MUSCARELLA AM, Aguirre S, Hao X, Waldvogel SM, et al
    Exploiting bone niches: progression of disseminated tumor cells to metastasis.
    J Clin Invest. 2021;131.
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  14. OSUKA S, Zhu D, Zhang Z, Li C, et al
    N-cadherin upregulation mediates adaptive radioresistance in glioblastoma.
    J Clin Invest. 2021;131.
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    February 2021
  15. FU J, Zuber J, Shonts B, Obradovic A, et al
    Lymphohematopoietic graft-versus-host responses promote mixed chimerism in patients receiving intestinal transplantation.
    J Clin Invest. 2021 Feb 25. pii: 141698. doi: 10.1172/JCI141698.
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  16. HE X, Wan J, Yang X, Zhang X, et al
    Bone marrow niche ATP levels determine leukemia-initiating cell activity via P2X7 in leukemic models.
    J Clin Invest. 2021;131.
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    January 2021
  17. FORTIN J, Bassi C, Ramachandran P, Li WY, et al
    Concerted roles of PTEN and ATM in controlling hematopoietic stem cell fitness and dormancy.
    J Clin Invest. 2021 Jan 14. pii: 131698. doi: 10.1172/JCI131698.
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  18. CAPITANO ML, Mohamad SF, Cooper S, Guo B, et al
    Mitigating oxygen stress enhances aged mouse hematopoietic stem cell numbers and function.
    J Clin Invest. 2021;131.
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  19. GUENANTIN AC, Jebeniani I, Leschik J, Watrin E, et al
    Targeting the histone demethylase LSD1 prevents cardiomyopathy in a mouse model of laminopathy.
    J Clin Invest. 2021;131.
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  20. UEZUMI A, Ikemoto-Uezumi M, Zhou H, Kurosawa T, et al
    Mesenchymal Bmp3b expression maintains skeletal muscle integrity and decreases in age-related sarcopenia.
    J Clin Invest. 2021;131.
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  21. MCGRATH MJ, Eramo MJ, Gurung R, Sriratana A, et al
    Defective lysosome reformation during autophagy causes skeletal muscle disease.
    J Clin Invest. 2021;131.
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    December 2020
  22. CONGRAS A, Hoareau-Aveilla C, Caillet N, Tosolini M, et al
    ALK-transformed mature T lymphocytes restore early thymus progenitor features.
    J Clin Invest. 2020;130:6395-6408.
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  23. FENG H, Xing W, Han Y, Sun J, et al
    Tendon-derived cathepsin K-expressing progenitor cells activate Hedgehog signaling to drive heterotopic ossification.
    J Clin Invest. 2020;130:6354-6365.
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    November 2020
  24. DE FRANCO E, Lytrivi M, Ibrahim H, Montaser H, et al
    YIPF5 mutations cause neonatal diabetes and microcephaly through endoplasmic reticulum stress.
    J Clin Invest. 2020 Nov 9. pii: 141455. doi: 10.1172/JCI141455.
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  25. PRUDENCIO M, Humphrey J, Pickles S, Brown AL, et al
    Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia.
    J Clin Invest. 2020;130:6080-6092.
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  26. BAIER J, Gansbauer M, Giessler C, Arnold H, et al
    Arginase impedes the resolution of colitis by altering the microbiome and metabolome.
    J Clin Invest. 2020;130:5703-5720.
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    October 2020
  27. MO J, Anastasaki C, Chen Z, Shipman T, et al
    Humanized neurofibroma model from induced pluripotent stem cells delineates tumor pathogenesis and developmental origins.
    J Clin Invest. 2020 Oct 27. pii: 139807. doi: 10.1172/JCI139807.
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  28. ALMOTIRI A, Alzahrani HAA, Menendez-Gonzalez JB, Abdelfattah A, et al
    Zeb1 modulates hematopoietic stem cell fates required for suppressing acute myeloid leukemia.
    J Clin Invest. 2020 Oct 27. pii: 129115. doi: 10.1172/JCI129115.
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  29. TIAN Y, Meng L, Wang Y, Li B, et al
    Graft-versus-host disease depletes plasmacytoid dendritic cell progenitors to impair tolerance induction.
    J Clin Invest. 2020 Oct 22. pii: 136774. doi: 10.1172/JCI136774.
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  30. SCHULMAN S, El-Darzi E, Florido MH, Friesen M, et al
    A coagulation defect arising from heterozygous premature termination of tissue factor.
    J Clin Invest. 2020;130:5302-5312.
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  31. LOVNICKI J, Gan Y, Feng T, Li Y, et al
    LIN28B promotes the development of neuroendocrine prostate cancer.
    J Clin Invest. 2020;130:5338-5348.
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  32. MACE EM, Paust S, Conte MI, Baxley RM, et al
    Human NK cell deficiency as a result of biallelic mutations in MCM10.
    J Clin Invest. 2020;130:5272-5286.
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    September 2020
  33. BIRESSI S, Filareto A, Rando TA
    Stem cell therapy for muscular dystrophies.
    J Clin Invest. 2020 Sep 18. pii: 142031. doi: 10.1172/JCI142031.
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    August 2020
  34. BRINKMEIER ML, Bando H, Camarano AC, Fujio S, et al
    Rathke's cleft-like cysts arise from Isl1 deletion in murine pituitary progenitors.
    J Clin Invest. 2020;130:4501-4515.
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  35. PINZON-GUZMAN C, Sangadala S, Riera KM, Popova EY, et al
    Noggin regulates foregut progenitor cell programming, and misexpression leads to esophageal atresia.
    J Clin Invest. 2020;130:4396-4410.
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    July 2020
  36. HU B, Lv X, Chen H, Xue P, et al
    Sensory nerves regulate mesenchymal stromal cell lineage commitment by tuning sympathetic tones.
    J Clin Invest. 2020;130:3483-3498.
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    June 2020
  37. WACLAWICZEK A, Hamilton A, Rouault-Pierre K, Abarrategi A, et al
    Mesenchymal niche remodeling impairs hematopoiesis via stanniocalcin 1 in acute myeloid leukemia.
    J Clin Invest. 2020;130:3038-3050.
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    May 2020
  38. LU H, Xie Y, Tran L, Lan J, et al
    Chemotherapy-induced S100A10 recruits KDM6A to facilitate OCT4-mediated breast cancer stemness.
    J Clin Invest. 2020 May 19. pii: 138577. doi: 10.1172/JCI138577.
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    April 2020
  39. KREUTMAIR S, Erlacher M, Andrieux G, Istvanffy R, et al
    Loss of the Fanconi anemia-associated protein NIPA causes bone marrow failure.
    J Clin Invest. 2020 Apr 27. pii: 126215. doi: 10.1172/JCI126215.
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  40. DUTTA R, Zhang TY, Kohnke T, Thomas D, et al
    Enasidenib drives human erythroid differentiation independently of isocitrate dehydrogenase 2.
    J Clin Invest. 2020;130:1843-1849.
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    March 2020
  41. LI L, Ghorbani M, Weisz-Hubshman M, Rousseau J, et al
    Lysine acetyltransferase 8 is involved in cerebral development and syndromic intellectual disability.
    J Clin Invest. 2020;130:1431-1445.
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    January 2020
  42. ASHLEY RJ, Yan H, Wang N, Hale J, et al
    Steroid-resistance in Diamond Blackfan anemia associates with p57Kip2 dysregulation in erythroid progenitors.
    J Clin Invest. 2020 Jan 21. pii: 132284. doi: 10.1172/JCI132284.
    >> Share

    December 2019
  43. OPPEZZO A, Bourseguin J, Renaud E, Pawlikowska P, et al
    Microphthalmia transcription factor expression contributes to bone marrow failure in Fanconi anemia.
    J Clin Invest. 2019 Dec 26. pii: 131540. doi: 10.1172/JCI131540.
    >> Share


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