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Articles published in
Proc Natl Acad Sci U S A
    November 2026
  1. JIMENEZ-ANDRADE Y, Sol S, Yoshida T, Tran M, et al
    The staphylococcal protease SspA perturbs the epidermal barrier and promotes IL-22-driven inflammation in allergen-exposed skin.
    Proc Natl Acad Sci U S A. 2026;123:e2611563123.
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    October 2026
  2. PARRISH M, Seraj M, Nikoueian H, Traugh N, et al
    Environmental chemical mixtures reprogram mammary epithelial development to epigenetic states associated with breast cancer.
    Proc Natl Acad Sci U S A. 2026;123:e2613054123.
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  3. ZHOU R, Xu T, Shen Z, Zhang Y, et al
    PAK4 exacerbates melanoma immunosuppression by promoting exosome release.
    Proc Natl Acad Sci U S A. 2026;123:e2536086123.
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  4. LIANG Q, Zhu H, Huang BC, Lin TK, et al
    Development of A10P3C, an isoform-selective inhibitor of EGLN2, for targeting breast cancer.
    Proc Natl Acad Sci U S A. 2026;123:e2613915123.
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  5. BIAN X, Xu M, Li N, Sun C, et al
    Genome stability disrupted by the circRBM39(4,5,6)-RPA2 axis represses breast tumorigenesis.
    Proc Natl Acad Sci U S A. 2026;123:e2614237123.
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    September 2026
  6. WU S, Chen S, Liu B, Liu Y, et al
    RHAMM drives formation of polyploid cancer cells and confers resistance to ER-targeted therapy in breast cancer.
    Proc Natl Acad Sci U S A. 2026;123:e2535342123.
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  7. KUANG SH, Abrenica AG, Kar N, Logue JS, et al
    Targeting cholesterol-dependent Piezo1 activation impairs amoeboid migration in melanoma cells.
    Proc Natl Acad Sci U S A. 2026;123:e2607369123.
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  8. NISHIDA J, Seehawer M, Rojas Jimenez E, Yan P, et al
    Breast cancer prevention by prophylactic Lalba mRNA-LNP vaccination.
    Proc Natl Acad Sci U S A. 2026;123:e2621855123.
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  9. WEDEL S, Claveras Cabezudo A, Rauh O, Olkhova E, et al
    Lysophospholipid-TRPV1 interactions in chemotherapy-induced neuropathy.
    Proc Natl Acad Sci U S A. 2026;123:e2613615123.
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  10. CHEN YC, Bollu VS, Kheirabadi S, LaPenna K, et al
    Convergent roles of GDF-15 in mechanotransduction, vascular disorganization, and immune suppression in melanoma.
    Proc Natl Acad Sci U S A. 2026;123:e2602594123.
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    August 2026
  11. LIU X, Liu Y, Li J, Wang Z, et al
    High-throughput deformability-based microfluidic sorting reveals metastatic cancer subpopulations.
    Proc Natl Acad Sci U S A. 2026;123:e2604094123.
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    July 2026
  12. SHETTIGAR M, Mouliere S, Isenegger L, DeVine AL, et al
    Oncogenic Galpha signaling requires AP-3-dependent recruitment to the endolysosomal compartment.
    Proc Natl Acad Sci U S A. 2026;123:e2615774123.
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  13. HARADA Y, Sasaki T, Obata-Ninomiya K, Matsuyama T, et al
    IL-13 signaling in cDC2 is required for systemic anaphylactic responses.
    Proc Natl Acad Sci U S A. 2026;123:e2608478123.
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    June 2026
  14. BU W, Lee TD, Anurag M, Dou Y, et al
    Rat somatic genome editing enables ER+ breast cancer modeling.
    Proc Natl Acad Sci U S A. 2026;123:e2529653123.
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  15. LAFIRENZE SJA, van Gerwen B, Quirindongo AI, Costermans N, et al
    Non-cell-autonomous mechanisms of tumor initiation and relapse by chromosomal instability.
    Proc Natl Acad Sci U S A. 2026;123:e2531095123.
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  16. MISHRA A, Abelman RO, Cunneely Q, Putaturo V, et al
    Dynamic monitoring of antibody drug conjugates targeting TROP2 or HER2 in breast cancer using circulating tumor cells.
    Proc Natl Acad Sci U S A. 2026;123:e2601563123.
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    May 2026
  17. ZHONG ZJ, Wei N, Li DJ, Shan TT, et al
    FGFR1-ETV1-CXCL1 signaling in dermal fibroblast orchestrates fibroblast-associated itch.
    Proc Natl Acad Sci U S A. 2026;123:e2536661123.
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  18. KAYA M, Johnsson O, Issdisai N, Paul S, et al
    NRF2 activation by myeloid cell-derived oxidative stress induces SNAI-driven features of EMT in breast cancer.
    Proc Natl Acad Sci U S A. 2026;123:e2521491123.
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  19. YANG X, Qiao X, Schmidt S, Eklund EA, et al
    ICMT supports BRAF(V600E)-driven tumor growth by membrane targeting of the CAAX protein INPP5E.
    Proc Natl Acad Sci U S A. 2026;123:e2601795123.
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  20. HAN YJ, Zhang J, Shariff M, Wu S, et al
    Regulation of antiviral and antitumor immunity by the BRCA1 pseudogene in human cancers.
    Proc Natl Acad Sci U S A. 2026;123:e2528911123.
    >> Share

  21. GARRIDO A, Tamayo-Torres E, Abdo S, Durham E, et al
    The antimetastatic effects of calorie restriction are negated by voluntary exercise in an aggressive breast cancer mouse model.
    Proc Natl Acad Sci U S A. 2026;123:e2524488123.
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    April 2026
  22. FARIAS A, Bridgeman VL, Rodrigues FS, Puttur F, et al
    Type I interferons induced upon respiratory viral infection impair lung metastatic initiation.
    Proc Natl Acad Sci U S A. 2026;123:e2412919123.
    >> Share

  23. BIDANY-MIZRAHI T, Maroun K, Mancini M, Hidmi O, et al
    WWOX maintains epidermal identity and suppresses EMT to prevent aggressive cutaneous squamous cell carcinoma.
    Proc Natl Acad Sci U S A. 2026;123:e2534844123.
    >> Share

  24. QIN D, Gao Y, Jiang H, Meng X, et al
    SCD1 licenses STING signaling through fatty acid desaturation-mediated membrane remodeling.
    Proc Natl Acad Sci U S A. 2026;123:e2528843123.
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  25. WILLIAMS SCP
    Profile of Helen M. Piwnica-Worms.
    Proc Natl Acad Sci U S A. 2026;123:e2609807123.
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  26. ABDULKAREEM NM, Jiang Y, Qi Y, Liu X, et al
    Resistance to neoadjuvant talazoparib in triple-negative breast cancer by BRN2-induced ATR/STAT3 pathways or SHLD2 subclone expansion.
    Proc Natl Acad Sci U S A. 2026;123:e2513742123.
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  27. TIAN Y, Bae S, Wu X, Rouen KC, et al
    Heat- and PIP2-dependent TRPM4 activity underlies mutually exclusive human diseases.
    Proc Natl Acad Sci U S A. 2026;123:e2530328123.
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  28. OLSON AW, Li J, Li XY, King L, et al
    Amoeboid-mesenchymal transition and the proteolytic control of cancer invasion plasticity.
    Proc Natl Acad Sci U S A. 2026;123:e2520717123.
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  29. LI Z, Wang Y, Chen Z, Liu R, et al
    WFDC21P is essential for G3BP1-mediated RIG-I activation and antitumor immunity in triple-negative breast cancer.
    Proc Natl Acad Sci U S A. 2026;123:e2532576123.
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  30. CHEN Z, Chen X, Yang K, Zhou H, et al
    Convergence of external and internal stressors on a stress-responsive enhancer of the Sonic hedgehog gene to induce hair disorders.
    Proc Natl Acad Sci U S A. 2026;123:e2529339123.
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    March 2026
  31. CUI W, Xiao H, Wen X, Li C, et al
    Identifying a cancer therapeutic target: Cell-SELEX identifies a membrane protein for aptamer-mediated growth suppression.
    Proc Natl Acad Sci U S A. 2026;123:e2514681123.
    >> Share

  32. FASSL A, Palacios Espinoza M, Butter D, Kolodziejczyk A, et al
    Regulation of the immune CD155-CD226-TIGIT axis by cyclin D-CDK4/6.
    Proc Natl Acad Sci U S A. 2026;123:e2522872123.
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  33. DING XH, Chen F, Yang F, Di GH, et al
    Phase separation of DDHD2 remodels lipid metabolism to dictate treatment sensitivity in luminal breast cancer.
    Proc Natl Acad Sci U S A. 2026;123:e2503019123.
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  34. TSOKKOU P, Holcmann M, Rindler K, Mieczkowski K, et al
    Psoriasis-like disease prevents squamous skin tumor development by neutrophil-driven inflammation.
    Proc Natl Acad Sci U S A. 2026;123:e2536378123.
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  35. CHEN HC, You SL, Lin CH, Sun CW, et al
    Elevated phthalate exposure and metabolic susceptibility increased breast cancer risk: A 20-y follow-up study in Taiwan.
    Proc Natl Acad Sci U S A. 2026;123:e2507008123.
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  36. COTTRELL O, Rowntree A, Chopra K, Mackellar E, et al
    HES1 oscillations are required for cell cycle reentry in oestrogen receptor-positive breast cancer cells.
    Proc Natl Acad Sci U S A. 2026;123:e2520724123.
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  37. GAO Y, Wang J, Qin Z, Xu N, et al
    NMI promotes the secretion of IL-17 and exacerbates psoriasis.
    Proc Natl Acad Sci U S A. 2026;123:e2511535123.
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  38. SENTHILKUMAR I, Vangheel J, Kumar V, McNamara L, et al
    Stress-dependent growth in breast cancer arises from a mechano-osmotic coupling and cell-sizing checkpoint.
    Proc Natl Acad Sci U S A. 2026;123:e2523159123.
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    February 2026
  39. YAN P, Bui T, Rojas Jimenez E, Kuang Y, et al
    Aging-associated differences in mammary tumor-initiating populations and immune evasion pathways in breast cancer.
    Proc Natl Acad Sci U S A. 2026;123:e2523254123.
    >> Share

  40. LOU KL, Bai JW, Liu HT, Lin LL, et al
    TROP2-targeted NIR-II fluorescence imaging for visualizing surgical margins and metastatic sentinel lymph nodes in breast cancers.
    Proc Natl Acad Sci U S A. 2026;123:e2519420123.
    >> Share

  41. BAIRD MA, Jewett CE, Malide DA, Kratz L, et al
    Lamin B receptor upregulation in metastatic melanoma causes nuclear envelope fragility in confined migration during cancer invasion.
    Proc Natl Acad Sci U S A. 2026;123:e2513031123.
    >> Share

  42. ROJAS-JIMENEZ E, Bui TM, Yan P, Li Z, et al
    Evaluation of targeted and immune combination therapies in a rat model of hormone receptor-positive breast cancer.
    Proc Natl Acad Sci U S A. 2026;123:e2501052123.
    >> Share

  43. SERRA M, Rediti M, Collet L, Lifrange F, et al
    Spatial transcriptomics reveals tumor microenvironment-driven subtypes of invasive lobular carcinoma.
    Proc Natl Acad Sci U S A. 2026;123:e2517567123.
    >> Share

  44. NADAV-ELIYAHU S, Bohrer C, Boocholez A, Kinor N, et al
    Nuclear speckles are regulatory hubs for viral and host mRNA expression during HSV-1 infection.
    Proc Natl Acad Sci U S A. 2026;123:e2511555123.
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    January 2026
  45. MORRISSEY RL, McDaniel JM, Chau GP, Su X, et al
    Elucidating cooperative genetic events in DCIS progression in mutant p53-driven breast cancer.
    Proc Natl Acad Sci U S A. 2026;123:e2526544123.
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    December 2025
  46. WANG J, Guo L, Tao Y, Xiao Y, et al
    Dysregulated NAMPT signaling underlines the immune-suppressive microenvironment in venous leg ulcers.
    Proc Natl Acad Sci U S A. 2025;122:e2512142122.
    >> Share

  47. COLLURA JL, Lei KC, Chandra M, Kervarrec T, et al
    Pharmacologic reversion of Merkel cell carcinoma via CBP/p300 inhibition.
    Proc Natl Acad Sci U S A. 2025;122:e2516667122.
    >> Share

  48. DELALEU J, Burstein V, Ansaldo E, Becaccece I, et al
    Maladaptive immunity to the microbiota promotes neuronal hyperinnervation and itch via IL-17A.
    Proc Natl Acad Sci U S A. 2025;122:e2525146122.
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  49. PANWAR HS, Vos TJ, Xie X, Jang HJ, et al
    Interprotomer communication and functional asymmetry in H/ACA snoRNPs.
    Proc Natl Acad Sci U S A. 2025;122:e2514683122.
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  50. FINCK AV, Wang Z, Gonzales D, Wellhausen N, et al
    Dual-targeted ping-pong CAR T cells: Leveraging peripheral expansion to improve solid tumor immunotherapy.
    Proc Natl Acad Sci U S A. 2025;122:e2518996122.
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  51. WANG X, Sun J, Lan B, Wang C, et al
    Asparagine endopeptidase prompts breast cancer-related pericardial calcification by regulating IGF2 and integrin alphavbeta5.
    Proc Natl Acad Sci U S A. 2025;122:e2512936122.
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  52. REINA J, Vallmajo-Martin Q, Ning J, Michi AN, et al
    LHPP expression in triple-negative breast cancer promotes tumor growth and metastasis by modulating the tumor microenvironment.
    Proc Natl Acad Sci U S A. 2025;122:e2505653122.
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    November 2025
  53. KLOSOWSKI ML, Cronise KE, Palmer EP, McAuliffe K, et al
    Breast cancer cell coculture induces normal lung fibroblast transition to CAFs, promoting tumor cell dormancy and therapy resistance.
    Proc Natl Acad Sci U S A. 2025;122:e2423894122.
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  54. WANG Z, Zeng Y, Tan Z, Chen Y, et al
    A unified framework for identification of cell-type-specific spatially variable genes in spatial transcriptomic studies.
    Proc Natl Acad Sci U S A. 2025;122:e2503952122.
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  55. LI Y, Qiu X, Sandusky Z, Tagliaferri K, et al
    METTL3-dependent m6A RNA methylation suppresses aberrant mammary epithelial differentiation and neoplastic transformation.
    Proc Natl Acad Sci U S A. 2025;122:e2514643122.
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  56. WU CCN, De Luna N, Hairston E, Jeffs ED, et al
    FZD7 expression marks mammary tumor-initiating cells.
    Proc Natl Acad Sci U S A. 2025;122:e2522465122.
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  57. NAWILAIJAROEN Y, Rocliffe HR, Austin-Williams S, Krilis G, et al
    MC1R determines healing outcomes in acute and chronic cutaneous wounds.
    Proc Natl Acad Sci U S A. 2025;122:e2503308122.
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  58. AYLON Y, Furth N, Pirona AC, Lavie A, et al
    p53 regulates the expression of histone modifiers to restrict stemness and maintain differentiated luminal identity in breast cancer.
    Proc Natl Acad Sci U S A. 2025;122:e2522646122.
    >> Share

    October 2025
  59. PIERCE SB, Kortbawi H, Gulsuner S, Mandell JB, et al
    Genetic regulation of the estrogen receptor and inherited predisposition to breast cancer.
    Proc Natl Acad Sci U S A. 2025;122:e2517736122.
    >> Share

  60. BERGMAN RE, Keeton CI, Sinha IR, Ling JP, et al
    Distinct and convergent effects of SF3B1 mutations in human breast cancer.
    Proc Natl Acad Sci U S A. 2025;122:e2505374122.
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    September 2025
  61. SAGLIMBENI J, Esteva E, Canales J, Perez OA, et al
    Peritumoral macrophages recruit eosinophils to promote antitumor immune responses in breast cancer.
    Proc Natl Acad Sci U S A. 2025;122:e2504645122.
    >> Share

  62. ZHANG J, Zhang J, Han L, Wu S, et al
    Inflammation awakens dormant cancer cells by modulating the epithelial-mesenchymal phenotypic state.
    Proc Natl Acad Sci U S A. 2025;122:e2515009122.
    >> Share

  63. DANG CAO TL, Kawanishi K, Hashimoto S, Hengphasatporn K, et al
    Tumor-expressed GPNMB orchestrates Siglec-9(+) TAM polarization and EMT to promote metastasis in triple-negative breast cancer.
    Proc Natl Acad Sci U S A. 2025;122:e2503081122.
    >> Share

  64. PERLA S, Stiegler AL, Yi JS, Enyenihi L, et al
    SHP2 genetic variants in NSML-associated RASopathies disrupt the PZR-IRX transcription factor signaling axis.
    Proc Natl Acad Sci U S A. 2025;122:e2503631122.
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    August 2025
  65. KHAN F, Liu Y, Whitfield D, Pang L, et al
    Macrophage TBK1 signaling drives the development and outgrowth of breast cancer brain metastasis.
    Proc Natl Acad Sci U S A. 2025;122:e2420793122.
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  66. KARNER ER, Wang M, Goel HL, Mercurio AM, et al
    GATA3 promotes ferroptosis resistance by repressing integrin beta1 signaling.
    Proc Natl Acad Sci U S A. 2025;122:e2427304122.
    >> Share

  67. PADRAO N, Gregoricchio S, Eickhoff N, Dong J, et al
    TRIM24 as a therapeutic target in endocrine treatment-resistant breast cancer.
    Proc Natl Acad Sci U S A. 2025;122:e2507571122.
    >> Share

  68. VUILLE JA, Tanriover C, Antmen E, Micalizzi DS, et al
    The E3 ligase HECTD4 regulates COX-2-dependent tumor progression and metastasis.
    Proc Natl Acad Sci U S A. 2025;122:e2425621122.
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    July 2025
  69. BOYER JA, Rosen EY, Sharma M, Dorso MA, et al
    eIF4A controls translation of estrogen receptor alpha and is a therapeutic target in advanced breast cancer.
    Proc Natl Acad Sci U S A. 2025;122:e2424286122.
    >> Share

  70. HORWITZ E, Dubash TD, Szabolcs A, Wittner BS, et al
    CDKN1B (p27/kip1) enhances drug-tolerant persister CTCs by restricting polyploidy following mitotic inhibitors.
    Proc Natl Acad Sci U S A. 2025;122:e2507203122.
    >> Share

  71. SUN R, Jiang P, Wang Z, Yan B, et al
    DNA2 protein destruction dictates DNA hyperexcision, cGAS-STING activation, and innate immune response in CDK12-deregulated cancers.
    Proc Natl Acad Sci U S A. 2025;122:e2413732122.
    >> Share

  72. BARNET MB, Jackson KJL, Masle-Farquhar E, Russell A, et al
    Common inherited loss-of-function mutations in the innate sensor NOD2 contribute to exceptional immune response to cancer immunotherapy.
    Proc Natl Acad Sci U S A. 2025;122:e2314258122.
    >> Share

  73. ZOU Y, Wang Z, Jiang Q, Kong X, et al
    UFMylation: A supervisor of the HIF1alpha pathway and a potential therapeutic target for anti-PD-1 combination therapy in hypoxic tumors.
    Proc Natl Acad Sci U S A. 2025;122:e2500562122.
    >> Share

  74. SURYAWANSHI RK, Patil CD, Borase H, Shukla D, et al
    Akt isoform specificity drives intrinsic immune regulation during HSV-1 infection.
    Proc Natl Acad Sci U S A. 2025;122:e2504962122.
    >> Share

  75. GUO J, Li K, Ming Y, Pan Y, et al
    A circular RNA overcomes acquired resistance to BET inhibitors by antagonizing IGF2BP2-mediated c-MYC translation in TNBC.
    Proc Natl Acad Sci U S A. 2025;122:e2504320122.
    >> Share

  76. LIM J, Jung HD, Park SY, Jeon M, et al
    Genome-scale knockout simulation and clustering analysis of drug-resistant breast cancer cells reveal drug sensitization targets.
    Proc Natl Acad Sci U S A. 2025;122:e2425384122.
    >> Share

    June 2025
  77. ZENG W, Guo H, Liu Q, Wong WH, et al
    Improving polygenic prediction from whole-genome sequencing data by leveraging predicted epigenomic features.
    Proc Natl Acad Sci U S A. 2025;122:e2419202122.
    >> Share

  78. OZAKI MK, Zhang Y, Bartlett AQ, de Wilde E, et al
    Reproductive state controls transcription in the murine liver, with implications for breast cancer liver metastasis.
    Proc Natl Acad Sci U S A. 2025;122:e2420174122.
    >> Share

  79. CROWTHER AJ, Kashem SW, Jewell ME, Le Chang H, et al
    Keratinocyte-TRPV1 sensory neuron interactions in a genetically controllable mouse model of chronic neuropathic itch.
    Proc Natl Acad Sci U S A. 2025;122:e2411724122.
    >> Share

  80. DING Q, Liu J, Wang Y, Kim J, et al
    Dual-laser "808 and 1,064 nm" strategy that circumvents the Achilles' heel of photothermal therapy.
    Proc Natl Acad Sci U S A. 2025;122:e2503574122.
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  81. ZERILLO L, Zotti T, Tutela A, Madera JR, et al
    The CARD14sh-BCL10-MALT1 complex regulates MAVS-mediated antiviral response in keratinocytes.
    Proc Natl Acad Sci U S A. 2025;122:e2500711122.
    >> Share

  82. SHARMA B, Aswin K, Jain T, Nasreen A, et al
    Mgat4b-mediated selective N-glycosylation regulates melanocyte development and melanoma progression.
    Proc Natl Acad Sci U S A. 2025;122:e2423831122.
    >> Share

    May 2025
  83. FERRERO G, Cardamone MD, Luca F, Bourk E, et al
    Nonproteolytic ubiquitination regulates chromatin occupancy by the NCoR/SMRT/HDAC3 corepressor complex in MCF-7 breast cancer cells.
    Proc Natl Acad Sci U S A. 2025;122:e2502805122.
    >> Share

    April 2025
  84. FOFFI E, Rugolo F, Ramamurthy N, Haight J, et al
    B cell-derived acetylcholine mitigates skin inflammation in mice through alpha9 nicotinic acetylcholine receptor-mediated signaling.
    Proc Natl Acad Sci U S A. 2025;122:e2501960122.
    >> Share

  85. CHEN YF, Zhang QH, Zhang ZW, Zhou YJ, et al
    SNX10 deficiency impairs sensitivity to anti-HER2 antibody-drug conjugates via altering HER2 trafficking in HER2-positive breast cancer.
    Proc Natl Acad Sci U S A. 2025;122:e2417586122.
    >> Share

  86. ZHAO X, Zhao Y, Li Z, Liu H, et al
    Proximity-activated DNA scanning encoded sequencing for massive access to membrane proteins nanoscale organization.
    Proc Natl Acad Sci U S A. 2025;122:e2425000122.
    >> Share

    March 2025
  87. NAZERAI L, Tsiavou C, Vardouli L, Schmiegelow K, et al
    Thiopurine therapy enhances immune checkpoint inhibitor efficacy in low-mutational burden melanoma: A promising anticancer approach.
    Proc Natl Acad Sci U S A. 2025;122:e2423246122.
    >> Share

  88. STAROSTECKA M, Jeong H, Hasenfeld P, Benito-Garagorri E, et al
    Structural variant and nucleosome occupancy dynamics postchemotherapy in a HER2+ breast cancer organoid model.
    Proc Natl Acad Sci U S A. 2025;122:e2415475122.
    >> Share

    February 2025
  89. YI J, Du J, Chen X, Nie RC, et al
    A circRNA-mRNA pairing mechanism regulates tumor growth and endocrine therapy resistance in ER-positive breast cancer.
    Proc Natl Acad Sci U S A. 2025;122:e2420383122.
    >> Share

  90. LEI L, Song Y, Yang L, Wang Y, et al
    Triethylamine-mediated protonation-deprotonation unlocks dual-drug self assembly to suppress breast cancer progression and metastasis.
    Proc Natl Acad Sci U S A. 2025;122:e2416796122.
    >> Share

    January 2025
  91. KRAKOWIAK PA, Flores ME, Cuddy SR, Whitford AL, et al
    Co-option of mitochondrial nucleic acid-sensing pathways by HSV-1 UL12.5 for reactivation from latent infection.
    Proc Natl Acad Sci U S A. 2025;122:e2413965122.
    >> Share

  92. CORRALES RM, Vincent J, Crobu L, Neish R, et al
    Tubulin detyrosination shapes Leishmania cytoskeletal architecture and virulence.
    Proc Natl Acad Sci U S A. 2025;122:e2415296122.
    >> Share

  93. QIN G, Shao X, Liu X, Xu J, et al
    A signaling molecule from intratumor bacteria promotes trastuzumab resistance in breast cancer cells.
    Proc Natl Acad Sci U S A. 2025;122:e2421710122.
    >> Share

  94. ZHENG M, Wang S, Tang K, Kong R, et al
    The CYLD-PARP1 feedback loop regulates DNA damage repair and chemosensitivity in breast cancer cells.
    Proc Natl Acad Sci U S A. 2025;122:e2413890121.
    >> Share

    December 2024
  95. GONZALEZ-FERNANDEZ M, Perry C, Gerhards NM, Francica P, et al
    Docetaxel response in BRCA1,p53-deficient mammary tumor cells is affected by Huntingtin and BAP1.
    Proc Natl Acad Sci U S A. 2024;121:e2402849121.
    >> Share

  96. CATTA-PRETA CMC, Ghosh K, Sacks DL, Ferreira TR, et al
    Single-cell atlas of Leishmania development in sandflies reveals the heterogeneity of transmitted parasites and their role in infection.
    Proc Natl Acad Sci U S A. 2024;121:e2406776121.
    >> Share

  97. SINHA A, Saini KK, Chandramouli A, Tripathi K, et al
    ACSL4-mediated H3K9 and H3K27 hyperacetylation upregulates SNAIL to drive TNBC metastasis.
    Proc Natl Acad Sci U S A. 2024;121:e2408049121.
    >> Share

  98. MATSUZAKI T, Fujii M, Noro H, Togo S, et al
    Simultaneous visualization of membrane fluidity and morphology defines adhesion signatures of cancer cells.
    Proc Natl Acad Sci U S A. 2024;121:e2412914121.
    >> Share

  99. ROUBILLE S, Escure T, Juillard F, Corpet A, et al
    The HUSH epigenetic repressor complex silences PML nuclear body-associated HSV-1 quiescent genomes.
    Proc Natl Acad Sci U S A. 2024;121:e2412258121.
    >> Share

    November 2024
  100. KASHYAP MP, Mishra B, Sinha R, Jin L, et al
    CD2 expressing innate lymphoid and T cells are critical effectors of immunopathogenesis in hidradenitis suppurativa.
    Proc Natl Acad Sci U S A. 2024;121:e2409274121.
    >> Share

  101. LADAK RJ, Choi JH, Luo J, Chen OJ, et al
    The 4EHP-mediated translational repression of cGAS impedes the host immune response against DNA viruses.
    Proc Natl Acad Sci U S A. 2024;121:e2413018121.
    >> Share

  102. DING X, Liang J, Sharko AC, Hilimire TA, et al
    Mediator kinase inhibitors suppress triple-negative breast cancer growth and extend tumor suppression by mTOR and AKT inhibitors.
    Proc Natl Acad Sci U S A. 2024;121:e2414501121.
    >> Share

  103. ARULRAJ T, Wang H, Deshpande A, Varadhan R, et al
    Virtual patient analysis identifies strategies to improve the performance of predictive biomarkers for PD-1 blockade.
    Proc Natl Acad Sci U S A. 2024;121:e2410911121.
    >> Share

    October 2024
  104. VALCIKOVA B, Vadovicova N, Smolkova K, Zacpalova M, et al
    eIF4F controls ERK MAPK signaling in melanomas with BRAF and NRAS mutations.
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  105. LI C, Kaur A, Pavlidaki A, Spenle C, et al
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  106. BALDASSARRI I, Tavakol DN, Graney PL, Chramiec AG, et al
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  107. ASEMOTA S, Effah W, Holt J, Johnson D, et al
    A molecular switch from tumor suppressor to oncogene in ER+ve breast cancer: Role of androgen receptor, JAK-STAT, and lineage plasticity.
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    September 2024
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    In vivo CRISPR screens identify Mga as an immunotherapy target in triple-negative breast cancer.
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    August 2024
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    Somatic mutations in tumor-infiltrating lymphocytes impact on antitumor immunity.
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  111. PIRONON N, Bourrat E, Prost C, Chen M, et al
    Splice modulation strategy applied to deep intronic variants in COL7A1 causing recessive dystrophic epidermolysis bullosa.
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    R-loop functions in Brca1-associated mammary tumorigenesis.
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    July 2024
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    Spatial molecular profiling of mixed invasive ductal and lobular breast cancers reveals heterogeneity in intrinsic molecular subtypes, oncogenic signatures, and mutations.
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  114. ZIN I, China A, Khan K, Nag JK, et al
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  115. ZHOU Q, Yu H, Chen Y, Ren J, et al
    The CRL3(KCTD10) ubiquitin ligase-USP18 axis coordinately regulates cystine uptake and ferroptosis by modulating SLC7A11.
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    June 2024
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  117. RUAN ML, Ni WX, Chu JCH, Lam TL, et al
    Iridium(III) carbene complexes as potent girdin inhibitors against metastatic cancers.
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  118. NEBO ID, Frew JW, Gudjonsson JE, Petukhova L, et al
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  119. JIN L, Kashyap MP, Haque ST, Li C, et al
    Reply to Nebo et al.: Pathogenesis of advanced hidradenitis suppurativa: Are there differences based on anatomical location, gender, and race?
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    May 2024

  120. Correction for Ichimura et al., Autoimmunity against melanoma differentiation-associated gene 5 induces interstitial lung disease mimicking dermatomyositis in mice.
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  121. CHEN J, Liu X, Zou Y, Gong J, et al
    A high-fat diet promotes cancer progression by inducing gut microbiota-mediated leucine production and PMN-MDSC differentiation.
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  122. ASHOKAN A, Sarkar S, Kamran MZ, Surnar B, et al
    Simultaneous targeting of peripheral and brain tumors with a therapeutic nanoparticle to disrupt metabolic adaptability at both sites.
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  123. GOYETTE MA, Stevens LE, DePinho CR, Seehawer M, et al
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    April 2024
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  125. ICHIMURA Y, Konishi R, Shobo M, Tanaka R, et al
    Autoimmunity against melanoma differentiation-associated gene 5 induces interstitial lung disease mimicking dermatomyositis in mice.
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  126. PIRES L, Khattak S, Pratavieira S, Calcada C, et al
    Femtosecond pulsed laser photodynamic therapy activates melanin and eradicates malignant melanoma.
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    March 2024
  127. WANG D, Tang M, Zhang P, Yang K, et al
    Activation of ERbeta hijacks the splicing machinery to trigger R-loop formation in triple-negative breast cancer.
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  128. GOUPIL E, Lacroix L, Briere J, Guga S, et al
    OSGN-1 is a conserved flavin-containing monooxygenase required to stabilize the intercellular bridge in late cytokinesis.
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  129. TAYLOR-PHILLIPS S, Jenkinson D, Stinton C, Kunar MA, et al
    Fatigue and vigilance in medical experts detecting breast cancer.
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    Telling time in tumor samples reveals diversity of clock disruption.
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