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Articles published in
Cancer Res
    September 2022
  1. TOKURA M, Nakayama J, Prieto-Vila M, Shiino S, et al
    Single-Cell Transcriptome Profiling Reveals Intratumoral Heterogeneity and Molecular Features of Ductal Carcinoma In Situ.
    Cancer Res. 2022;82:3236-3248.
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  2. SMALLEY I, Smalley KSM
    Space Is the Place: Mapping the Cell-Cell Interactions That Predict Immunotherapy Responses in Melanoma.
    Cancer Res. 2022;82:3198-3200.
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  3. XU X, Wang K, Vera O, Verma A, et al
    Gain of Chromosome 1q Perturbs a Competitive Endogenous RNA Network to Promote Melanoma Metastasis.
    Cancer Res. 2022;82:3016-3031.
    >> Share

  4. SRIVASTAVA A, Tommasi C, Sessions D, Mah A, et al
    MAB21L4 Deficiency Drives Squamous Cell Carcinoma via Activation of RET.
    Cancer Res. 2022;82:3143-3157.
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    August 2022
  5. XU X, Wang K, Vera O, Verma A, et al
    Gain of chromosome 1q perturbs a competitive endogenous RNA network to promote melanoma metastasis.
    Cancer Res. 2022 Aug 31. pii: 706990. doi: 10.1158/0008-5472.CAN-22-0283.
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  6. SCHATTON T, Itoh Y, Martins C, Rasbach E, et al
    Inhibition of melanoma cell-intrinsic Tim-3 stimulates MAPK-dependent tumorigenesis.
    Cancer Res. 2022 Aug 18. pii: 708039. doi: 10.1158/0008-5472.CAN-22-0970.
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  7. MOASSER MM
    Inactivating Amplified HER2: Challenges, Dilemmas, and Future Directions.
    Cancer Res. 2022;82:2811-2820.
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  8. WU C, Jarrett AM, Zhou Z, Elshafeey N, et al
    MRI-based digital models forecast patient-specific treatment responses to neoadjuvant chemotherapy in triple-negative breast cancer.
    Cancer Res. 2022 Aug 1. pii: 707362. doi: 10.1158/0008-5472.CAN-22-1329.
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    July 2022
  9. TIMPERI E, Gueguen P, Molgora M, Magagna I, et al
    Lipid-associated macrophages are induced by cancer-associated fibroblasts and mediate immune suppression in breast cancer.
    Cancer Res. 2022 Jul 21. pii: 707127. doi: 10.1158/0008-5472.CAN-22-1427.
    >> Share

  10. ANTORANZ A, Van Herck Y, Bolognesi MM, Lynch SM, et al
    Mapping the immune landscape in metastatic melanoma reveals localized cell-cell interactions that predict immunotherapy response.
    Cancer Res. 2022 Jul 14. pii: 707010. doi: 10.1158/0008-5472.CAN-22-0363.
    >> Share

  11. CHEN F, Park SL, Wilkens LR, Wan P, et al
    Genetic Risk of Second Primary Cancer in Breast Cancer Survivors: The Multiethnic Cohort Study.
    Cancer Res. 2022 Jul 14. pii: 707009. doi: 10.1158/0008-5472.CAN-21-4461.
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    June 2022
  12. KALRA R, Chen CH, Wang J, Salam AB, et al
    Poziotinib inhibits HER2 mutant-driven therapeutic resistance and multi-organ metastasis in breast cancer.
    Cancer Res. 2022 Jun 23. pii: 705013. doi: 10.1158/0008-5472.CAN-21-3106.
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  13. CLARIDGE SE, Hopkins BD
    PI3King the Environment for Growth: PI3K Activation Drives Transcriptome Changes That Support Oncogenic Growth.
    Cancer Res. 2022;82:2216-2218.
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  14. LADEWIG E, Michelini F, Jhaveri K, Castel P, et al
    The Oncogenic PI3K-Induced Transcriptomic Landscape Reveals Key Functions in Splicing and Gene Expression Regulation.
    Cancer Res. 2022;82:2269-2280.
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  15. ZHANG Z, Golomb L, Meyerson M
    Functional Genomic Analysis of CDK4 and CDK6 Gene Dependency across Human Cancer Cell Lines.
    Cancer Res. 2022;82:2171-2184.
    >> Share

  16. CAI W, Nguyen MQ, Wilski NA, Purwin TJ, et al
    A Genome-wide screen identifies PDPK1 as a target to enhance the efficacy of MEK1/2 inhibitors in NRAS mutant melanoma.
    Cancer Res. 2022 Jun 3. pii: 699338. doi: 10.1158/0008-5472.CAN-21-3217.
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    May 2022
  17. BONFILL-TEIXIDOR E, Iurlaro R, Handl C, Wichmann J, et al
    Activity and resistance of a brain-permeable paradox breaker BRAF inhibitor in melanoma brain metastasis.
    Cancer Res. 2022 May 18. pii: 699020. doi: 10.1158/0008-5472.CAN-21-4152.
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  18. KOPANJA D, Chand V, O'Brien EM, Mukhopadhyay NK, et al
    Transcriptional repression by FoxM1 suppresses tumor differentiation and promotes metastasis of breast cancer.
    Cancer Res. 2022 May 18. pii: 699021. doi: 10.1158/0008-5472.CAN-22-0410.
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  19. WEI YT, Wang XR, Yan C, Huang F, et al
    Thymosin alpha-1 Reverses M2 Polarization of Tumor-Associated Macrophages during Efferocytosis.
    Cancer Res. 2022;82:1991-2002.
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  20. FATHERREE JP, Guarin JR, McGinn RA, Naber SP, et al
    Chemotherapy-Induced Collagen IV Drives Cancer Cell Motility through Activation of Src and Focal Adhesion Kinase.
    Cancer Res. 2022;82:2031-2044.
    >> Share

  21. ROVERA C, Berestjuk I, Lecacheur M, Tavernier C, et al
    Secretion of IL1 by Dedifferentiated Melanoma Cells Inhibits JAK1-STAT3-Driven Actomyosin Contractility of Lymph Node Fibroblastic Reticular Cells.
    Cancer Res. 2022;82:1774-1788.
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  22. MARCZYK M, Gunasekharan V, Casadevall D, Qing T, et al
    Comprehensive Analysis of Metabolic Isozyme Targets in Cancer.
    Cancer Res. 2022;82:1698-1711.
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  23. ISKANDER K, Paquet M, Brayton C, Jaiswal AK, et al
    Editor's Note: Deficiency of NRH: Quinone Oxidoreductase 2 Increases Susceptibility to 7,12-Dimethylbenz(a)anthracene and Benzo(a)pyrene-Induced Skin Carcinogenesis.
    Cancer Res. 2022;82:1845.
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  24. LUND AW
    Be Easy and Chill: Melanoma Cells Tell Lymph Node Fibroblasts to Relax.
    Cancer Res. 2022;82:1692-1694.
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    April 2022
  25. RODRIGUEZ-TIRADO C, Kale N, Carlini MJ, Shrivastava N, et al
    NR2F1 is a barrier to dissemination of early stage breast cancer cells.
    Cancer Res. 2022 Apr 26. pii: 694636. doi: 10.1158/0008-5472.CAN-21-4145.
    >> Share

  26. SINGH S, Lee N, Pedroza DA, Bado IL, et al
    Chemotherapy coupled to macrophage inhibition induces T-cell and B-cell infiltration and durable regression in triple-negative breast cancer.
    Cancer Res. 2022 Apr 20. pii: 694629. doi: 10.1158/0008-5472.CAN-21-3714.
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  27. PELLEGRINO B, Herencia-Ropero A, Llop-Guevara A, Pedretti F, et al
    Preclinical In Vivo Validation of the RAD51 Test for Identification of Homologous Recombination-Deficient Tumors and Patient Stratification.
    Cancer Res. 2022;82:1646-1657.
    >> Share

  28. QUIROS-GONZALEZ I, Tomaszewski MR, Golinska MA, Brown E, et al
    Photoacoustic Tomography Detects Response and Resistance to Bevacizumab in Breast Cancer Mouse Models.
    Cancer Res. 2022;82:1658-1668.
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  29. WANG H, Xu H, Chen W, Cheng M, et al
    Rab13 sustains breast cancer stem cells by supporting tumor-stroma crosstalk.
    Cancer Res. 2022 Apr 8. pii: 694330. doi: 10.1158/0008-5472.CAN-21-4097.
    >> Share

  30. ELWAKEEL E, Bruggemann M, Wagih J, Lityagina O, et al
    Disruption of Prostaglandin E2 Signaling in Cancer-Associated Fibroblasts Limits Mammary Carcinoma Growth but Promotes Metastasis.
    Cancer Res. 2022;82:1380-1395.
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  31. HONG Z, Liu T, Wan L, Fa P, et al
    Targeting Squalene Epoxidase Interrupts Homologous Recombination via the ER Stress Response and Promotes Radiotherapy Efficacy.
    Cancer Res. 2022;82:1298-1312.
    >> Share

    March 2022
  32. WILSON Z, Odedra R, Wallez Y, Wijnhoven PWG, et al
    ATR Inhibitor AZD6738 (Ceralasertib) Exerts Antitumor Activity as a Monotherapy and in Combination with Chemotherapy and the PARP Inhibitor Olaparib.
    Cancer Res. 2022;82:1140-1152.
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    February 2022
  33. BHATIA S, Kramer M, Russo S, Naik P, et al
    Patient-derived triple-negative breast cancer organoids provide robust model systems that recapitulate tumor-intrinsic characteristics.
    Cancer Res. 2022 Feb 18. pii: 681619. doi: 10.1158/0008-5472.CAN-21-2807.
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  34. SCHEIDMANN MC, Castro-Giner F, Strittmatter K, Krol I, et al
    An In Vivo CRISPR Screen Identifies Stepwise Genetic Dependencies of Metastatic Progression.
    Cancer Res. 2022;82:681-694.
    >> Share

  35. LIAO C, Glodowski CR, Fan C, Liu J, et al
    Integrated Metabolic Profiling and Transcriptional Analysis Reveals Therapeutic Modalities for Targeting Rapidly Proliferating Breast Cancers.
    Cancer Res. 2022;82:665-680.
    >> Share

  36. BOONEN RACM, Wiegant WW, Celosse N, Vroling B, et al
    Functional Analysis Identifies Damaging CHEK2 Missense Variants Associated with Increased Cancer Risk.
    Cancer Res. 2022;82:615-631.
    >> Share

  37. GILL JG, Leef SN, Ramesh V, Martin-Sandoval MS, et al
    A short isoform of spermatogenic enzyme GAPDHS functions as a metabolic switch and limits metastasis in melanoma.
    Cancer Res. 2022 Feb 11. pii: 0008-5472.CAN-21-2062.
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  38. LI XQ, Zhang R, Lu H, Yue XM, et al
    Extracellular vesicle-packaged CDH11 and ITGA5 induce the premetastatic niche for bone colonization of breast cancer cells.
    Cancer Res. 2022 Feb 11. pii: 0008-5472.CAN-21-1331.
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    January 2022
  39. LI Z, Wu Y, Yates ME, Tasdemir N, et al
    Hotspot ESR1 mutations are multimodal and contextual modulators of breast cancer metastasis.
    Cancer Res. 2022 Jan 25. pii: 0008-5472.CAN-21-2576.
    >> Share

  40. LIU T, Zhou L, Xiao Y, Andl T, et al
    BRAF Inhibitors Reprogram Cancer-Associated Fibroblasts to Drive Matrix Remodeling and Therapeutic Escape in Melanoma.
    Cancer Res. 2022 Jan 21. pii: 0008-5472.CAN-21-0614.
    >> Share

  41. MAJORINI MT, Colombo MP, Lecis D
    Few, but efficient: the role of mast cells in breast cancer and other solid tumors.
    Cancer Res. 2022 Jan 19. pii: 0008-5472.CAN-21-3424.
    >> Share

  42. HAJ-SHOMALY J, Vorontsova A, Barenholz-Cohen T, Levi-Galibov O, et al
    T Cells Promote Metastasis by Regulating Extracellular Matrix Remodeling following Chemotherapy.
    Cancer Res. 2022;82:278-291.
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  43. ZHU WJ, Chen X, Guo XY, Liu HT, et al
    Low glucose-induced overexpression of HOXC-AS3 promotes metabolic reprogramming of breast cancer.
    Cancer Res. 2022 Jan 14. pii: 0008-5472.CAN-21-1179.
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    December 2021
  44. XU Y, Ren W, Li Q, Duan C, et al
    LncRNA Uc003xsl.1-mediated activation of the NF-kappaB/IL8 axis promotes progression of triple-negative breast cancer.
    Cancer Res. 2021 Dec 29. pii: 0008-5472.CAN-21-1446.
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  45. BEETHAM H, Griffith BGC, Murina O, Loftus AE, et al
    Loss of Integrin-linked kinase sensitizes breast cancer to SRC inhibitors.
    Cancer Res. 2021 Dec 17. pii: 0008-5472.CAN-21-0373.
    >> Share

  46. OBA T, Kajihara R, Yokoi T, Repasky EA, et al
    Neoadjuvant In Situ Immunomodulation Enhances Systemic Antitumor Immunity against Highly Metastatic Tumors.
    Cancer Res. 2021;81:6183-6195.
    >> Share

  47. MOORE J, Ma L, Lazar A, Barcellos-Hoff MH, et al
    Mammary tumor-derived transplants as breast cancer models to evaluate tumor-immune interactions and therapeutic responses.
    Cancer Res. 2021 Dec 13. pii: 0008-5472.CAN-21-0253.
    >> Share

    November 2021
  48. CHOI SR, Hwang CY, Lee J, Cho KH, et al
    Network Analysis Identifies Regulators of Basal-Like Breast Cancer Reprogramming and Endocrine Therapy Vulnerability.
    Cancer Res. 2021 Nov 29. pii: 0008-5472.CAN-21-0621.
    >> Share

  49. LIU W, Stachura P, Xu HC, Varaljai R, et al
    BAFF attenuates immunosuppressive monocytes in the melanoma tumor microenvironment.
    Cancer Res. 2021 Nov 22. pii: 0008-5472.CAN-21-1171.
    >> Share

  50. YUAN H, Yan L, Wu M, Shang Y, et al
    Analysis of the estrogen receptor-associated lncRNA landscape identifies a role for ERLC1 in breast cancer progression.
    Cancer Res. 2021 Nov 22. pii: 0008-5472.CAN-21-1155.
    >> Share

  51. TUBITA A, Lombardi Z, Tusa I, Lazzeretti A, et al
    Inhibition of ERK5 elicits cellular senescence in melanoma via the cyclin-dependent kinase inhibitor p21.
    Cancer Res. 2021 Nov 19. pii: 0008-5472.CAN-21-0993.
    >> Share

  52. SUBRAMANIAN S, Daquinag AC, AghaAmiri S, Ghosh SC, et al
    Characterization of Peptides Targeting Metastatic Tumor Cells as Probes for Cancer Detection and Vehicles for Therapy Delivery.
    Cancer Res. 2021;81:5756-5764.
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  53. JANJANAM J, Pano G, Wang R, Minden-Birkenmaier BA, et al
    Matricellular Protein WISP2 Is an Endogenous Inhibitor of Collagen Linearization and Cancer Metastasis.
    Cancer Res. 2021;81:5666-5677.
    >> Share

  54. YOKOYAMA S, Takahashi A, Kikuchi R, Nishibu S, et al
    SOX10 regulates melanoma immunogenicity through an IRF4-IRF1 axis.
    Cancer Res. 2021 Nov 2. pii: 0008-5472.CAN-21-2078.
    >> Share

  55. DAMODARAN S, Hortobagyi GN
    Estrogen Receptor: A Paradigm for Targeted Therapy.
    Cancer Res. 2021;81:5396-5398.
    >> Share

  56. GRISARU-TAL S, Dulberg S, Beck L, Zhang C, et al
    Metastasis-Entrained Eosinophils Enhance Lymphocyte-Mediated Antitumor Immunity.
    Cancer Res. 2021;81:5555-5571.
    >> Share

  57. TEMPS C, Lietha D, Webb ER, Li XF, et al
    A Conformation Selective Mode of Inhibiting SRC Improves Drug Efficacy and Tolerability.
    Cancer Res. 2021;81:5438-5450.
    >> Share

  58. HINSHAW DC, Hanna A, Lama-Sherpa T, Metge B, et al
    Hedgehog Signaling Regulates Metabolism and Polarization of Mammary Tumor-Associated Macrophages.
    Cancer Res. 2021;81:5425-5437.
    >> Share

    October 2021
  59. DONE SJ, Kanwar N, Balde Z, Nair R, et al
    Heterogeneity of circulating tumor cell-associated genomic gains in breast cancer and its association with the host immune response.
    Cancer Res. 2021 Oct 28. pii: 0008-5472.CAN-21-1079.
    >> Share

  60. GOU X, Anurag M, Lei JT, Kim BJ, et al
    Transcriptional reprogramming differentiates active from inactive ESR1 fusions in endocrine therapy-refractory metastatic breast cancer.
    Cancer Res. 2021 Oct 28. pii: 0008-5472.CAN-21-1256.
    >> Share

  61. PATEL A, Garcia-Closas M, Olshan AF, Perou CM, et al
    Gene level germline contributions to clinical risk of recurrence scores in Black and White breast cancer patients.
    Cancer Res. 2021 Oct 28. pii: 0008-5472.CAN-21-1207.
    >> Share

  62. AGUIRRE-PORTOLES C, Payne R, Trautz A, Foskett JK, et al
    ZIP9 is a Druggable Determinant of Sex Differences in Melanoma.
    Cancer Res. 2021 Oct 27. pii: 0008-5472.CAN-21-0982.
    >> Share

  63. HUGGINS DN, LaRue RS, Wang Y, Knutson TP, et al
    Characterizing Macrophage Diversity in Metastasis-Bearing Lungs Reveals a Lipid-Associated Macrophage Subset.
    Cancer Res. 2021;81:5284-5295.
    >> Share

  64. SALTARI A, Dzung A, Quadri M, Tiso N, et al
    Specific activation of the CD271 intracellular domain in combination with chemotherapy or targeted therapy inhibits melanoma progression.
    Cancer Res. 2021 Oct 13. pii: 0008-5472.CAN-21-0117.
    >> Share

  65. VALENCIA JC, Erwin-Cohen RA, Clavijo PE, Allen C, et al
    Myeloid derived suppressive cell expansion promotes melanoma growth and severity of autoimmunity by inhibiting CD40/IL-27 regulation in macrophages.
    Cancer Res. 2021 Oct 12. pii: 0008-5472.CAN-21-1148.
    >> Share

  66. WOITEK R, McLean MA, Ursprung S, Rueda OM, et al
    Hyperpolarized carbon-13 MRI for early response assessment of neoadjuvant chemotherapy in breast cancer patients.
    Cancer Res. 2021 Oct 8. pii: 0008-5472.CAN-21-1499.
    >> Share

    September 2021
  67. LIU C, Qiang J, Deng Q, Xia J, et al
    ALDH1A1 activity in tumor-initiating cells remodels myeloid-derived suppressor cells to promote breast cancer progression.
    Cancer Res. 2021 Sep 27. pii: 0008-5472.CAN-21-1337.
    >> Share

  68. ZHAO X, Li J, Liu Z, Powers S, et al
    Combinatorial CRISPR/Cas9 Screening Reveals Epistatic Networks of Interacting Tumor Suppressor Genes and Therapeutic Targets in Human Breast Cancer.
    Cancer Res. 2021 Sep 24. pii: 0008-5472.CAN-21-2555.
    >> Share

  69. ANSARI KI, Bhan A, Saotome M, Tyagi A, et al
    Autocrine GMCSF Signaling Contributes to Growth of HER2(+) Breast Leptomeningeal Carcinomatosis.
    Cancer Res. 2021;81:4723-4735.
    >> Share

  70. CAPPELLO S, Sung HM, Ickes C, Gibhardt CS, et al
    Protein signatures of NK cell-mediated melanoma killing predict response to immunotherapies.
    Cancer Res. 2021 Sep 13. pii: 0008-5472.CAN-21-0164.
    >> Share

  71. EVANS KW, Yuca E, Scott SS, Zhao M, et al
    Oxidative phosphorylation is a metabolic vulnerability in chemotherapy-resistant triple negative breast cancer.
    Cancer Res. 2021 Sep 13. pii: 0008-5472.CAN-20-3242.
    >> Share

  72. FAURE C, Djerbi-Bouillie R, Domingot A, Bouzinba-Segard H, et al
    Allosteric inhibition of HER2 by Moesin-mimicking compounds targets HER2-positive cancers and brain metastases.
    Cancer Res. 2021 Sep 7. pii: 0008-5472.CAN-21-0162.
    >> Share

    August 2021
  73. LIU J, Rebecca VW, Kossenkov AV, Connelly T, et al
    Neural crest-like stem cell transcriptome analysis identifies LPAR1 in melanoma progression and therapy resistance.
    Cancer Res. 2021 Aug 30. pii: 0008-5472.CAN-20-1496.
    >> Share

  74. ZUO H, Yang D, Wan Y
    Fam20C regulates bone resorption and breast cancer bone metastasis through osteopontin and BMP4.
    Cancer Res. 2021 Aug 25. pii: 0008-5472.CAN-20-3328.
    >> Share

  75. YU TJ, Liu YY, Li XG, Lian B, et al
    PDSS1-mediated activation of CAMK2A-STAT3 signaling promotes metastasis in triple-negative breast cancer.
    Cancer Res. 2021 Aug 18. pii: 0008-5472.CAN-21-0747.
    >> Share

  76. AHIRWAR DK, Charan M, Mishra S, Verma AK, et al
    Slit2 inhibits breast cancer metastasis by activating M1-like phagocytic and anti-fibrotic macrophages.
    Cancer Res. 2021 Aug 16. pii: 0008-5472.CAN-20-3909.
    >> Share

  77. PULEO J, Polyak K
    The MCF10 Model of Breast Tumor Progression.
    Cancer Res. 2021;81:4183-4185.
    >> Share

  78. APOSTOLIDI M, Vathiotis IA, Muthusamy V, Gaule P, et al
    Targeting Pyruvate Kinase M2 Phosphorylation Reverses Aggressive Cancer Phenotypes.
    Cancer Res. 2021;81:4346-4359.
    >> Share

  79. TANG K, Zhu L, Chen J, Wang D, et al
    Hypoxia promotes breast cancer cell growth by activating a glycogen metabolic program.
    Cancer Res. 2021 Aug 4. pii: 0008-5472.CAN-21-0753.
    >> Share

  80. WANG Y, Kartasalo K, Weitz P, Acs B, et al
    Predicting molecular phenotypes from histopathology images: a transcriptome-wide expression-morphology analysis in breast cancer.
    Cancer Res. 2021 Aug 2. pii: 0008-5472.CAN-21-0482.
    >> Share

    July 2021
  81. ROLLISON DE, Amorrortu RP, Zhao Y, Messina JL, et al
    Cutaneous human papillomaviruses and the risk of keratinocyte carcinomas.
    Cancer Res. 2021 Jul 15. pii: 0008-5472.CAN-21-0805.
    >> Share

  82. GOMEZ TEJEDA ZANUDO J, Mao P, Alcon C, Kowalski K, et al
    Cell line-specific network models of ER+ breast cancer identify potential PI3Kalpha inhibitor resistance mechanisms and drug combinations.
    Cancer Res. 2021 Jul 13. pii: 0008-5472.CAN-21-1208.
    >> Share

  83. WHITE JR, Thompson DT, Koch KE, Kiriazov BS, et al
    AP-2alpha-mediated activation of E2F and EZH2 drives melanoma metastasis.
    Cancer Res. 2021 Jul 1. pii: 0008-5472.CAN-21-0772.
    >> Share

  84. TAKAYAMA KI, Honma T, Suzuki T, Kondoh Y, et al
    Targeting Epigenetic and Posttranscriptional Gene Regulation by PSF Impairs Hormone Therapy-Refractory Cancer Growth.
    Cancer Res. 2021;81:3495-3508.
    >> Share

  85. STEINER MC, Marston JL, Iniguez LP, Bendall ML, et al
    Locus-Specific Characterization of Human Endogenous Retrovirus Expression in Prostate, Breast, and Colon Cancers.
    Cancer Res. 2021;81:3449-3460.
    >> Share

  86. CHOI H, Kwon J, Cho MS, Sun Y, et al
    Targeting DDX3X Triggers Antitumor Immunity via a dsRNA-Mediated Tumor-Intrinsic Type I Interferon Response.
    Cancer Res. 2021;81:3607-3620.
    >> Share

  87. YOO KH, Tang JJ, Rashid MA, Cho CH, et al
    Nicotinamide Mononucleotide Prevents Cisplatin-Induced Cognitive Impairments.
    Cancer Res. 2021;81:3727-3737.
    >> Share

    June 2021
  88. LAINE A, Nagelli SG, Farrington C, Butt U, et al
    CIP2A interacts with TopBP1 and drives basal-like breast cancer tumorigenesis.
    Cancer Res. 2021 Jun 18. pii: 0008-5472.CAN-20-3651.
    >> Share

  89. CANO A, Lopez-Menendez C, Vazquez-Naharro A, Santos V, et al
    E2A modulates stemness, metastasis, and therapeutic resistance of breast cancer.
    Cancer Res. 2021 Jun 18. pii: 0008-5472.CAN-20-2685.
    >> Share

  90. SHARIF GM, Campbell MJ, Nasir A, Sengupta S, et al
    An AIB1 isoform alters enhancer access and enables progression of early stage triple-negative breast cancer.
    Cancer Res. 2021 Jun 16. pii: 0008-5472.CAN-20-3625.
    >> Share

  91. BHAN A, Ansari KI, Chen MY, Jandial R, et al
    Inhibition of Jumonji Histone Demethylases Selectively Suppresses HER2(+) Breast Leptomeningeal Carcinomatosis Growth via Inhibition of GMCSF Expression.
    Cancer Res. 2021;81:3200-3214.
    >> Share

  92. ZHOU Q, Howard ME, Tu X, Zhu Q, et al
    Inhibition of ATM Induces Hypersensitivity to Proton Irradiation by Upregulating Toxic End Joining.
    Cancer Res. 2021;81:3333-3346.
    >> Share

  93. HARRIS RJ, Cheung A, Ng JCF, Laddach R, et al
    Tumor-Infiltrating B Lymphocyte Profiling Identifies IgG-Biased, Clonally Expanded Prognostic Phenotypes In Triple-Negative Breast Cancer.
    Cancer Res. 2021 Jun 15. pii: 0008-5472.CAN-20-3773.
    >> Share

  94. WANG T, Farvid MS, Kang JH, Holmes MD, et al
    Diabetes Risk Reduction Diet and Survival After Breast Cancer Diagnosis.
    Cancer Res. 2021 Jun 9. pii: 0008-5472.CAN-21-0256.
    >> Share

  95. ZERHOUNI M, Martin AR, Furstoss N, Gutierrez VS, et al
    Dual covalent inhibition of PKM and IMPDH targets metabolism in cutaneous metastatic melanoma.
    Cancer Res. 2021 Jun 7. pii: 0008-5472.CAN-20-2114.
    >> Share

  96. HAN S, Yan Y, Ren Y, Hu Y, et al
    LncRNA SAMMSON Mediates Adaptive Resistance to RAF Inhibition in BRAF-Mutant Melanoma Cells.
    Cancer Res. 2021;81:2918-2929.
    >> Share

    May 2021
  97. YANG B, Li X, Fu Y, Guo E, et al
    MEK Inhibition Remodels the Immune Landscape of Mutant KRAS Tumors to Overcome Resistance to PARP and Immune Checkpoint Inhibitors.
    Cancer Res. 2021;81:2714-2729.
    >> Share

  98. SHAN P, Yang F, Qi H, Hu Y, et al
    Alteration of MDM2 by the small molecule YF438 exerts anti-tumor effects in triple-negative breast cancer.
    Cancer Res. 2021 May 13. pii: 0008-5472.CAN-20-0922.
    >> Share

  99. HAPACH LA, Carey SP, Schwager SC, Taufalele PV, et al
    Phenotypic heterogeneity and metastasis of breast cancer cells.
    Cancer Res. 2021 May 11. pii: 0008-5472.CAN-20-1799.
    >> Share

  100. GUO Q, Bartish M, Goncalves C, Huang F, et al
    The MNK1/2-eIF4E axis supports immune suppression and metastasis in postpartum breast cancer.
    Cancer Res. 2021 May 11. pii: 0008-5472.CAN-20-3143.
    >> Share

  101. LIU Z, Guo C, Das SK, Yu X, et al
    Engineering T Cells to Express Tumoricidal MDA-7/IL24 Enhances Cancer Immunotherapy.
    Cancer Res. 2021;81:2429-2441.
    >> Share

    April 2021
  102. SHARMA D
    Towards Taming the Bugs to Improve the Drugs for Breast Cancer.
    Cancer Res. 2021;81:1937-1939.
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  103. FUHRMAN BJ, Moore SC, Byrne C, Makhoul I, et al
    Association of the Age at Menarche with Site-Specific Cancer Risks in Pooled Data from Nine Cohorts.
    Cancer Res. 2021;81:2246-2255.
    >> Share

  104. OLAFSDOTTIR T, Stacey SN, Sveinbjornsson G, Thorleifsson G, et al
    Loss-of-Function Variants in the Tumor-Suppressor Gene PTPN14 Confer Increased Cancer Risk.
    Cancer Res. 2021;81:1954-1964.
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  105. KHARKWAL SS, Johndrow CT, Veerapen N, Kharkwal H, et al
    Serial Stimulation of Invariant Natural Killer T Cells with Covalently Stabilized Bispecific T-cell Engagers Generates Antitumor Immunity While Avoiding Anergy.
    Cancer Res. 2021;81:1788-1801.
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  106. CHEN F, Chen Z, Guan T, Zhou Y, et al
    N6-methyladenosine regulates mRNA stability and translation efficiency of KRT7 to promote breast cancer lung metastasis.
    Cancer Res. 2021 Apr 1. pii: 0008-5472.CAN-20-3779.
    >> Share

    March 2021
  107. DE SEMIR D, Bezrookove V, Nosrati M, Dar AA, et al
    Nuclear receptor coactivator NCOA3 regulates ultraviolet radiation-induced DNA damage and melanoma susceptibility.
    Cancer Res. 2021 Mar 25. pii: 0008-5472.CAN-20-3450.
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  108. LI CI, Flanagan MR, Tang MC, Porter PL, et al
    Bisphosphonate Use and Breast Cancer Risk among Women with Ductal Carcinoma In Situ.
    Cancer Res. 2021 Mar 24. pii: 0008-5472.CAN-20-4100.
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  109. HU L, Su L, Cheng H, Mo C, et al
    Single-cell RNA sequencing reveals the cellular origin and evolution of breast cancer in BRCA1 mutation carriers.
    Cancer Res. 2021 Mar 16. pii: 0008-5472.CAN-20-2123.
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  110. CARVAJAL-MALDONADO D, Wood RD
    Regulating Poltheta in Breast Cancer.
    Cancer Res. 2021;81:1441-1442.
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  111. PRODHOMME MK, Pommier RM, Franchet C, Fauvet F, et al
    EMT Transcription Factor ZEB1 Represses the Mutagenic POLtheta-Mediated End-Joining Pathway in Breast Cancers.
    Cancer Res. 2021;81:1595-1606.
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  112. HAN YJ, Zhang J, Lee JH, Mason JM, et al
    The BRCA1 Pseudogene Negatively Regulates Antitumor Responses through Inhibition of Innate Immune Defense Mechanisms.
    Cancer Res. 2021;81:1540-1551.
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  113. TERVONEN TA, Pant SM, Belitskin D, Englund JI, et al
    Oncogenic Ras Disrupts Epithelial Integrity by Activating the Transmembrane Serine Protease Hepsin.
    Cancer Res. 2021;81:1513-1527.
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  114. ZHOU Y, Jin X, Ma J, Ding D, et al
    HDAC5 Loss Impairs RB Repression of Pro-Oncogenic Genes and Confers CDK4/6 Inhibitor Resistance in Cancer.
    Cancer Res. 2021;81:1486-1499.
    >> Share

  115. IIZUKA S, Quintavalle M, Navarro JC, Gribbin KP, et al
    Serine-Threonine Kinase TAO3-Mediated Trafficking of Endosomes Containing the Invadopodia Scaffold TKS5alpha Promotes Cancer Invasion and Tumor Growth.
    Cancer Res. 2021;81:1472-1485.
    >> Share

  116. CAI Y, Xu G, Wu F, Michelini F, et al
    Genomic alterations in PIK3CA-mutated breast cancer result in mTORC1 activation and limit sensitivity to PI3Kalpha inhibitors.
    Cancer Res. 2021 Mar 8. pii: 0008-5472.CAN-20-3232.
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  117. DAI M, Boudreault J, Wang N, Poulet S, et al
    Differential Regulation of Cancer Progression by CDK4/6 Plays a Central Role in DNA Replication and Repair Pathways.
    Cancer Res. 2021;81:1332-1346.
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  118. KUMARASAMY V, Vail P, Nambiar R, Witkiewicz AK, et al
    Functional Determinants of Cell Cycle Plasticity and Sensitivity to CDK4/6 Inhibition.
    Cancer Res. 2021;81:1347-1360.
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    February 2021
  119. TARTEY S, Neale G, Vogel P, Malireddi RKS, et al
    A MyD88/IL-1R axis regulates PD-1 expression on tumor-associated macrophages and sustains their immunosuppressive function in melanoma.
    Cancer Res. 2021 Feb 22. pii: 0008-5472.CAN-20-3510.
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  120. YU R, Longo J, van Leeuwen JE, Zhang C, et al
    Mevalonate pathway inhibition slows breast cancer metastasis via reduced N-glycosylation abundance and branching.
    Cancer Res. 2021 Feb 18. pii: 0008-5472.CAN-20-2642.
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  121. LEE S, Amgad M, Mobadersany P, McCormick M, et al
    Interactive Classification of Whole-Slide Imaging Data for Cancer Researchers.
    Cancer Res. 2021;81:1171-1177.
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  122. KARLSSON MJ, Costa Svedman F, Tebani A, Kotol D, et al
    Inflammation and apolipoproteins are potential biomarkers for stratification of cutaneous melanoma patients for immunotherapy and targeted therapy.
    Cancer Res. 2021 Feb 11. pii: 0008-5472.CAN-20-2000.
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  123. SHAMI SHAH A, Cao X, White AC, Baskin JM, et al
    PLEKHA4 Promotes Wnt/beta-catenin Signaling-Mediated G1/S Transition and Proliferation in Melanoma.
    Cancer Res. 2021 Feb 11. pii: 0008-5472.CAN-20-2584.
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  124. QUINN HM, Vogel R, Popp O, Mertins P, et al
    YAP and beta-catenin cooperate to drive oncogenesis in basal breast cancer.
    Cancer Res. 2021 Feb 11. pii: 0008-5472.CAN-20-2801.
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  125. BOSHUIZEN J, Pencheva N, Krijgsman O, D'Empaire Altimari D, et al
    Cooperative targeting of immunotherapy-resistant melanoma and lung cancer by an AXL-targeting antibody-drug conjugate and immune checkpoint blockade.
    Cancer Res. 2021 Feb 2. pii: 0008-5472.CAN-20-0434.
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  126. SCHAFF DL, Singh S, Kim KB, Sutcliffe MD, et al
    Fragmentation of Small-cell Lung Cancer Regulatory States in Heterotypic Microenvironments.
    Cancer Res. 2021 Feb 2. pii: 0008-5472.CAN-20-1036.
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  127. SINGH S, Sutcliffe MD, Repich K, Atkins KA, et al
    Pan-cancer Drivers are Recurrent Transcriptional Regulatory Heterogeneities in Early-stage Luminal Breast Cancer.
    Cancer Res. 2021 Feb 2. pii: 0008-5472.CAN-20-1034.
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  128. SUTCLIFFE MD, Galvao RP, Wang L, Kim J, et al
    Premalignant oligodendrocyte precursor cells stall in a heterogeneous state of replication stress prior to gliomagenesis.
    Cancer Res. 2021 Feb 2. pii: 0008-5472.CAN-20-1037.
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  129. HUANG L, Zhai Y, La J, Lui JW, et al
    Targeting pan-ETS factors inhibits melanoma progression.
    Cancer Res. 2021 Feb 1. pii: 0008-5472.CAN-19-1668.
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  130. WYSS CB, Duffey N, Peyvandi S, Barras D, et al
    Gain of HIF1 Activity and Loss of miRNA let-7d Promote Breast Cancer Metastasis to the Brain via the PDGF/PDGFR Axis.
    Cancer Res. 2021;81:594-605.
    >> Share

  131. HERMIDA-PRADO F, Jeselsohn R
    The ESR1 Mutations: From Bedside to Bench to Bedside.
    Cancer Res. 2021;81:537-538.
    >> Share

  132. PARDINI B, Dragomir MP
    SCIRT lncRNA Blocks the Shot of Breast Cancer Cells Self-Renewal Mechanism.
    Cancer Res. 2021;81:535-536.
    >> Share

  133. CRESSWELL GM, Wang B, Kischuk EM, Broman MM, et al
    Folate Receptor Beta Designates Immunosuppressive Tumor-Associated Myeloid Cells That Can Be Reprogrammed with Folate-Targeted Drugs.
    Cancer Res. 2021;81:671-684.
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  134. ZAGORAC S, de Giorgio A, Dabrowska A, Kalisz M, et al
    SCIRT lncRNA Restrains Tumorigenesis by Opposing Transcriptional Programs of Tumor-Initiating Cells.
    Cancer Res. 2021;81:580-593.
    >> Share

    January 2021
  135. THOMAS C, Karagounis IV, Srivastava RK, Vrettos N, et al
    Estrogen receptor beta-mediated inhibition of actin-based cell migration suppresses metastasis of inflammatory breast cancer.
    Cancer Res. 2021 Jan 29. pii: 0008-5472.CAN-20-2743.
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  136. PECK B, Bland P, Mavrommati I, Muirhead G, et al
    3D Functional Genomics Screens Identify CREBBP as a Targetable Driver in Aggressive Triple-Negative Breast Cancer.
    Cancer Res. 2021 Jan 28. pii: 0008-5472.CAN-20-1822.
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  137. SANDIFORD OA, Donnelly RJ, El-Far M, Burgmeyer LM, et al
    Mesenchymal stem cell-secreted extracellular vesicles instruct stepwise dedifferentiation of breast cancer cells into dormancy at the bone marrow perivascular region.
    Cancer Res. 2021 Jan 26. pii: 0008-5472.CAN-20-2434.
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  138. BARNABAS GD, Sang Lee J, Shami T, Harel M, et al
    Serine biosynthesis is a metabolic vulnerability in IDH2-driven breast cancer progression.
    Cancer Res. 2021 Jan 26. pii: 0008-5472.CAN-19-3020.
    >> Share

  139. DI MODICA M, Gargari G, Regondi V, Bonizzi A, et al
    Gut microbiota condition the therapeutic efficacy of trastuzumab in HER2-positive breast cancer.
    Cancer Res. 2021 Jan 22. pii: 0008-5472.CAN-20-1659.
    >> Share

  140. MESTRE-FARRERA A, Bruch-Oms M, Pena R, Rodriguez-Morato J, et al
    Glutamine-Directed Migration of Cancer-Activated Fibroblasts Facilitates Epithelial Tumor Invasion.
    Cancer Res. 2021;81:438-451.
    >> Share

  141. KOLAPALLI SP, Sahu R, Chauhan NR, Jena KK, et al
    RNA-Binding RING E3-Ligase DZIP3/hRUL138 Stabilizes Cyclin D1 to Drive Cell-Cycle and Cancer Progression.
    Cancer Res. 2021;81:315-331.
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  142. DHIMOLEA E, de Matos Simoes R, Kansara D, Weng X, et al
    Pleiotropic Mechanisms Drive Endocrine Resistance in the Three-Dimensional Bone Microenvironment.
    Cancer Res. 2021;81:371-383.
    >> Share

  143. XING F, Zhao D, Wu SY, Tyagi A, et al
    Epigenetic and post-transcriptional modulation of SOS1 can promote breast cancer metastasis through obesity-activated c-Met signaling in African American women.
    Cancer Res. 2021 Jan 14. pii: 0008-5472.CAN-19-4031.
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  144. MILLER KD, Pniewski K, Perry CE, Papp SB, et al
    Targeting ACSS2 with a transition state mimetic inhibits triple-negative breast cancer growth.
    Cancer Res. 2021 Jan 7. pii: 0008-5472.CAN-20-1847.
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  145. LIU Z, Sun L, Cai Y, Shen S, et al
    Hypoxia-induced suppression of alternative splicing of MBD2 promotes breast cancer metastasis via activation of FZD1.
    Cancer Res. 2021 Jan 5. pii: 0008-5472.CAN-20-2876.
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  146. JEONG GY, Park MK, Choi HJ, An HW, et al
    NSD3-Induced Methylation of H3K36 Activates NOTCH Signaling to Drive Breast Tumor Initiation and Metastatic Progression.
    Cancer Res. 2021;81:77-90.
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    December 2020
  147. YAKOVIAN O, Sajman J, Arafeh R, Neve-Oz Y, et al
    MEK inhibition reverses aberrant signaling in melanoma cells through reorganization of NRas and BRAF in self nano-clusters.
    Cancer Res. 2020 Dec 21. pii: 0008-5472.CAN-20-1205.
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  148. KARLSSON T, Johansson T, Hoglund J, Ek WE, et al
    Time-dependent effects of oral contraceptive use on breast, ovarian and endometrial cancers.
    Cancer Res. 2020 Dec 17. pii: 0008-5472.CAN-20-2476.
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  149. ZHENG W, Ranoa DRE, Huang X, Hou Y, et al
    RIG-I-Like Receptor LGP2 Is Required for Tumor Control by Radiotherapy.
    Cancer Res. 2020;80:5633-5641.
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  150. WANG F, Zheng W, Bailey CE, Mayer IA, et al
    Racial/Ethnic Disparities in All-Cause Mortality Among Patients Diagnosed with Triple-Negative Breast Cancer.
    Cancer Res. 2020 Dec 3. pii: 0008-5472.CAN-20-3094.
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  151. FALVO P, Orecchioni S, Hillje R, Raveane A, et al
    Cyclophosphamide and vinorelbine activate stem-like CD8+ T cells and improve anti-PD-1 efficacy in triple-negative breast cancer.
    Cancer Res. 2020 Dec 2. pii: 0008-5472.CAN-20-1818.
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  152. DOUGLASS SM, Fane ME, Sanseviero E, Ecker BL, et al
    Myeloid-derived suppressor cells are a major source of Wnt5A in the melanoma microenvironment and depend on Wnt5A for full suppressive activity.
    Cancer Res. 2020 Dec 1. pii: 0008-5472.CAN-20-1238.
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  153. MIAR A, Arnaiz E, Bridges E, Beedie S, et al
    Hypoxia Induces Transcriptional and Translational Downregulation of the Type I IFN Pathway in Multiple Cancer Cell Types.
    Cancer Res. 2020;80:5245-5256.
    >> Share

  154. HEASTER TM, Humayun M, Yu J, Beebe DJ, et al
    Autofluorescence Imaging of 3D Tumor-Macrophage Microscale Cultures Resolves Spatial and Temporal Dynamics of Macrophage Metabolism.
    Cancer Res. 2020;80:5408-5423.
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  155. LIAPIS E, Klemm U, Karlas A, Reber J, et al
    Resolution of Spatial and Temporal Heterogeneity in Bevacizumab-Treated Breast Tumors by Eigenspectra Multispectral Optoacoustic Tomography.
    Cancer Res. 2020;80:5291-5304.
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    November 2020
  156. FARVID MS, Holmes MD, Chen WY, Rosner BA, et al
    Postdiagnostic Fruit and Vegetable Consumption and Breast Cancer Survival: Prospective Analyses in the Nurses' Health Studies.
    Cancer Res. 2020;80:5134-5143.
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  157. MAMO M, Ye IC, DiGiacomo JW, Park JY, et al
    Hypoxia Alters the Response to Anti-EGFR Therapy by Regulating EGFR Expression and Downstream Signaling in a DNA Methylation-Specific and HIF-Dependent Manner.
    Cancer Res. 2020;80:4998-5010.
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  158. SOOTOME H, Fujita H, Ito K, Ochiiwa H, et al
    Futibatinib Is a Novel Irreversible FGFR 1-4 Inhibitor That Shows Selective Antitumor Activity against FGFR-Deregulated Tumors.
    Cancer Res. 2020;80:4986-4997.
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  159. KIMMEL GJ, Dane M, Heiser LM, Altrock PM, et al
    Integrating Mathematical Modeling with High-Throughput Imaging Explains How Polyploid Populations Behave in Nutrient-Sparse Environments.
    Cancer Res. 2020;80:5109-5120.
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  160. LAUKO A, Mu Z, Gutmann DH, Naik UP, et al
    Junctional Adhesion Molecules in Cancer: A Paradigm for the Diverse Functions of Cell-Cell Interactions in Tumor Progression.
    Cancer Res. 2020;80:4878-4885.
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  161. ARNESEN S, Blanchard Z, Williams MM, Berrett KC, et al
    Estrogen receptor alpha mutations in breast cancer cells cause gene expression changes through constant activity and secondary effects.
    Cancer Res. 2020 Nov 12. pii: 0008-5472.CAN-20-1171.
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  162. WILLIAMS MM, Spoelstra NS, Arnesen S, O'Neill KI, et al
    Steroid hormone receptor and infiltrating immune cell status reveals therapeutic vulnerabilities of ESR1 mutant breast cancer.
    Cancer Res. 2020 Nov 12. pii: 0008-5472.CAN-20-1200.
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  163. CHEN F, Ding K, Priedigkeit N, Elangovan A, et al
    Single-cell transcriptomic heterogeneity in invasive ductal and lobular breast cancer cells.
    Cancer Res. 2020 Nov 4. pii: 0008-5472.CAN-20-0696.
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  164. WANG Y, Luo M, Chen Y, Wang Y, et al
    ZMYND8 expression in breast cancer cells blocks T-lymphocyte surveillance to promote tumor growth.
    Cancer Res. 2020 Nov 4. pii: 0008-5472.CAN-20-1710.
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    October 2020
  165. CRUMP LS, Wyatt G, Rutherford TR, Richer JK, et al
    Hormonal regulation of Semaphorin 7a in ER+ breast cancer drives therapeutic resistance.
    Cancer Res. 2020 Oct 29. pii: 0008-5472.CAN-20-1601.
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  166. WILLS CA, Liu X, Chen L, Zhao Y, et al
    Chemotherapy-Induced Upregulation of Small Extracellular Vesicle-Associated PTX3 Accelerates Breast Cancer Metastasis.
    Cancer Res. 2020 Oct 28. pii: 0008-5472.CAN-20-1976.
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  167. OGRODZINSKI MP, Teoh ST, Lunt SY
    Targeting subtype-specific metabolic preferences in nucleotide biosynthesis inhibits tumor growth in a breast cancer model.
    Cancer Res. 2020 Oct 28. pii: 0008-5472.CAN-20-1666.
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  168. SMALLEY M, Natarajan SK, Mondal J, Goldman D, et al
    Nano-Engineered Disruption of Heat shock protein 90 (Hsp90) Targets Drug-Induced Resistance and Relieves Natural Killer Cell Suppression in Breast Cancer.
    Cancer Res. 2020 Oct 19. pii: 0008-5472.CAN-19-4036.
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  169. PAUDEL BB, Lewis JE, Hardeman KN, Hayford CE, et al
    An Integrative Gene Expression and Mathematical Flux Balance Analysis Identifies Targetable Redox Vulnerabilities in Melanoma Cells.
    Cancer Res. 2020;80:4565-4577.
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  170. CHAMBERLIN T, Clack M, Silvers C, Kuziel G, et al
    Targeting Obesity-Induced Macrophages during Preneoplastic Growth Promotes Mammary Epithelial Stem/Progenitor Activity, DNA Damage, and Tumor Formation.
    Cancer Res. 2020;80:4465-4475.
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  171. BLANCO-GOMEZ A, Hontecillas-Prieto L, Corchado-Cobos R, Garcia-Sancha N, et al
    Stromal SNAI2 is required for ERBB2 breast cancer progression.
    Cancer Res. 2020 Oct 6. pii: 0008-5472.CAN-20-0278.
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  172. SHANI O, Vorobyov T, Monteran L, Lavie D, et al
    Fibroblast-derived IL-33 facilitates breast cancer metastasis by modifying the immune microenvironment and driving type-2 immunity.
    Cancer Res. 2020 Oct 6. pii: 0008-5472.CAN-20-2116.
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  173. PARK D, Bergin SM, Jones D, Ru P, et al
    Ablation of the Brca1-Palb2 Interaction Phenocopies Fanconi Anemia in Mice.
    Cancer Res. 2020;80:4172-4184.
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  174. ANLAS AA, Nelson CM
    Soft Microenvironments Induce Chemoresistance by Increasing Autophagy Downstream of Integrin-Linked Kinase.
    Cancer Res. 2020;80:4103-4113.
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  175. DWANE L, O'Connor AE, Das S, Moran B, et al
    A functional genomic screen identifies the deubiquitinase USP11 as a novel transcriptional regulator of ERalpha in breast cancer.
    Cancer Res. 2020 Oct 1. pii: 0008-5472.CAN-20-0214.
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  176. YANG C, Wu J, Liu X, Wang Y, et al
    Circadian Rhythm Is Disrupted by ZNF704 in Breast Carcinogenesis.
    Cancer Res. 2020;80:4114-4128.
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    September 2020
  177. BELLERI M, Paganini G, Coltrini D, Ronca R, et al
    BETA-GALACTOSYLCERAMIDASE PROMOTES MELANOMA GROWTH VIA MODULATION OF CERAMIDE METABOLISM.
    Cancer Res. 2020 Sep 30. pii: 0008-5472.CAN-19-3382.
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  178. BOLKESTEIN M, Wong JKL, Thewes V, Korber V, et al
    Chromothripsis in human breast cancer.
    Cancer Res. 2020 Sep 24. pii: 0008-5472.CAN-20-1920.
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  179. MAHAUAD-FERNANDEZ WD, Felsher DW
    The Myc and Ras Partnership in Cancer: Indistinguishable Alliance or Contextual Relationship?
    Cancer Res. 2020;80:3799-3802.
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  180. GHERGUROVICH JM, Esposito M, Chen Z, Wang JZ, et al
    Glucose-6-Phosphate Dehydrogenase Is Not Essential for K-Ras-Driven Tumor Growth or Metastasis.
    Cancer Res. 2020;80:3820-3829.
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  181. WESTCOTT JM, Camacho S, Nasir A, Huysman ME, et al
    DeltaNp63-Regulated Epithelial-to-Mesenchymal Transition State Heterogeneity Confers a Leader-Follower Relationship That Drives Collective Invasion.
    Cancer Res. 2020;80:3933-3944.
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  182. BHAT-NAKSHATRI P, Kumar B, Simpson E, Ludwig KK, et al
    Breast cancer cell detection and characterization from breast milk-derived cells.
    Cancer Res. 2020 Sep 15. pii: 0008-5472.CAN-20-1030.
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  183. HUANG M, O'Shaughnessy J, Zhao J, Haiderali A, et al
    Association of Pathological Complete Response with Long-Term Survival Outcomes in Triple-Negative Breast Cancer: A Meta-analysis.
    Cancer Res. 2020 Sep 14. pii: 0008-5472.CAN-20-1792.
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  184. TUBEUF H, Caputo SM, Sullivan T, Rondeaux J, et al
    Calibration of Pathogenicity Due to Variant-Induced Leaky Splicing Defects by Using BRCA2 Exon 3 as a Model System.
    Cancer Res. 2020;80:3593-3605.
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    August 2020
  185. PRZANOWSKI P, Lou S, Tihagam RD, Mondal T, et al
    Oncogenic TRIM37 links chemoresistance and metastatic fate in triple-negative breast cancer.
    Cancer Res. 2020 Aug 27. pii: 0008-5472.CAN-20-1459.
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  186. ABRAHAMSSON A, Vazquez Rodriguez G, Dabrosin C
    Fulvestrant-mediated attenuation of the innate immune response decreases ER+ breast cancer growth in vivo more effectively than tamoxifen.
    Cancer Res. 2020 Aug 27. pii: 0008-5472.CAN-20-1705.
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  187. FANG Z, Wang Y, Wang Z, Xu M, et al
    ERINA is an estrogen-responsive lncRNA that drives breast cancer through the E2F1/RB1 pathway.
    Cancer Res. 2020 Aug 21. pii: 0008-5472.CAN-20-1031.
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  188. CONWAY ME, McDaniel JM, Graham JM, Guillen KP, et al
    STAT3 and GR cooperate to drive gene expression and growth of basal-like triple-negative breast cancer.
    Cancer Res. 2020 Aug 19. pii: 0008-5472.CAN-20-1379.
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  189. IRURZUN-ARANA I, McDonald TO, Troconiz IF, Michor F, et al
    Pharmacokinetic Profiles Determine Optimal Combination Treatment Schedules in Computational Models of Drug Resistance.
    Cancer Res. 2020;80:3372-3382.
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  190. AMBROSONE CB, Higgins MJ
    Relationships between breast feeding and breast cancer subtypes: lessons learned from studies in humans and in mice.
    Cancer Res. 2020 Aug 14. pii: 0008-5472.CAN-20-0077.
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  191. VERRET B, Sourisseau T, Stefanovska B, Mosele F, et al
    The Influence of Cancer Molecular Subtypes and Treatment on the Mutation Spectrum in Metastatic Breast Cancers.
    Cancer Res. 2020;80:3062-3069.
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    July 2020
  192. DATTILO R, Mottini C, Camera E, Lamolinara A, et al
    Pyrvinium pamoate induces death of triple-negative breast cancer stem-like cells and reduces metastases through effects on lipid anabolism.
    Cancer Res. 2020 Jul 23. pii: 0008-5472.CAN-19-1184.
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  193. WANG Y, Chen Y, Bao L, Zhang B, et al
    CHD4 promotes breast cancer progression as a coactivator of hypoxia-inducible factors.
    Cancer Res. 2020 Jul 22. pii: 0008-5472.CAN-20-1049.
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  194. CAI C
    A Novel Mechanism to Induce BRCAness in Cancer Cells.
    Cancer Res. 2020;80:2977-2978.
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  195. BRIDGES AE, Ramachandran S, Pathania R, Parwal U, et al
    RAD51AP1 deficiency reduces tumor growth by targeting stem cell self-renewal.
    Cancer Res. 2020 Jul 14. pii: 0008-5472.CAN-19-3713.
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  196. SILVESTRI VL, Henriet E, Linville RM, Wong AD, et al
    A tissue-engineered 3D microvessel model reveals the dynamics of mosaic vessel formation in breast cancer.
    Cancer Res. 2020 Jul 14. pii: 0008-5472.CAN-19-1564.
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  197. DAI C, Charlestin V, Wang M, Walker ZT, et al
    Aquaporin-7 Regulates the Response to Cellular Stress in Breast Cancer.
    Cancer Res. 2020 Jul 6. pii: 0008-5472.CAN-19-2269.
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  198. CHAO JT, Hollman R, Meyers WM, Meili F, et al
    A Premalignant Cell-Based Model for Functionalization and Classification of PTEN Variants.
    Cancer Res. 2020;80:2775-2789.
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  199. BOUCHET M, Laine A, Boyault C, Proponnet-Guerault M, et al
    ERRalpha Expression in Bone Metastases Leads to an Exacerbated Antitumor Immune Response.
    Cancer Res. 2020;80:2914-2926.
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  200. QUINTANA E, Schulze CJ, Myers DR, Choy TJ, et al
    Allosteric Inhibition of SHP2 Stimulates Antitumor Immunity by Transforming the Immunosuppressive Environment.
    Cancer Res. 2020;80:2889-2902.
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  201. BUI NHB, Napoli M, Davis AJ, Abbas HA, et al
    Spatiotemporal Regulation of DeltaNp63 by TGFbeta-Regulated miRNAs Is Essential for Cancer Metastasis.
    Cancer Res. 2020;80:2833-2847.
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    June 2020
  202. BANIK D, Noonepalle S, Hadley M, Palmer E, et al
    HDAC6 plays a non-canonical role in the regulation of anti-tumor immune responses, dissemination, and invasiveness of breast cancer.
    Cancer Res. 2020 Jun 30. pii: 0008-5472.CAN-19-3738.
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  203. ZHOU H, Blevins MA, Hsu JY, Kong D, et al
    Identification of a Small-Molecule Inhibitor That Disrupts the SIX1/EYA2 Complex, EMT, and Metastasis.
    Cancer Res. 2020;80:2689-2702.
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  204. VASIUKOV G, Novitskaya T, Zijlstra A, Owens P, et al
    Myeloid Cell-Derived TGFbeta Signaling Regulates ECM Deposition in Mammary Carcinoma via Adenosine-Dependent Mechanisms.
    Cancer Res. 2020;80:2628-2638.
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  205. ZHOU Z, Zhou H, Ponzoni L, Luo A, et al
    EIF3H Orchestrates Hippo Pathway-Mediated Oncogenesis via Catalytic Control of YAP Stability.
    Cancer Res. 2020;80:2550-2563.
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  206. SUN L, Li CW, Chung EM, Yang R, et al
    Targeting Glycosylated PD-1 Induces Potent Antitumor Immunity.
    Cancer Res. 2020;80:2298-2310.
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    May 2020
  207. WALKER E, Liu Y, Kim I, Biro M, et al
    A Protease-Activated Fluorescent Probe Allows Rapid Visualization of Keratinocyte Carcinoma during Excision.
    Cancer Res. 2020;80:2045-2055.
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  208. TROTTER TN, Shuptrine CW, Tsao LC, Marek RD, et al
    IL-26, a non-canonical mediator of DNA inflammatory stimulation, promotes TNBC engraftment and progression in association with neutrophils.
    Cancer Res. 2020 May 4. pii: 0008-5472.CAN-18-3825.
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    April 2020
  209. THIES KA, Hammer AM, Hildreth BE, Steck SA, et al
    Stromal platelet-derived growth factor receptor-beta signaling promotes breast cancer metastasis in the brain.
    Cancer Res. 2020 Apr 23. pii: 0008-5472.CAN-19-3731.
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  210. CHU W, Zhang X, Qi L, Fu Y, et al
    The EZH2-PHACTR2-AS1-ribosome axis induces genomic instability and promotes growth and metastasis in breast cancer.
    Cancer Res. 2020 Apr 20. pii: 0008-5472.CAN-19-3326.
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  211. KENNEDY KM, Zilkens R, Allen WM, Foo KY, et al
    Diagnostic Accuracy of Quantitative Micro-Elastography for Margin Assessment in Breast-Conserving Surgery.
    Cancer Res. 2020;80:1773-1783.
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  212. VANNA R, Morasso C, Marcinno B, Piccotti F, et al
    Raman Spectroscopy Reveals That Biochemical Composition of Breast Microcalcifications Correlates with Histopathologic Features.
    Cancer Res. 2020;80:1762-1772.
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  213. ROBERTS MS, Sahni JM, Schrock MS, Piemonte KM, et al
    LIN9 and NEK2 Are Core Regulators of Mitotic Fidelity That Can Be Therapeutically Targeted to Overcome Taxane Resistance.
    Cancer Res. 2020;80:1693-1706.
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  214. PEDERSEN L, Panahandeh P, Siraji MI, Knappskog S, et al
    Golgi-localized PAQR4 mediates Anti-apoptotic Ceramidase Activity in Breast Cancer.
    Cancer Res. 2020 Apr 14. pii: 0008-5472.CAN-19-3177.
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  215. MOSHKOVICH N, Ochoa HJ, Tang B, Yang HH, et al
    Peptidylarginine deiminase IV (PADI4) regulates breast cancer stem cells via a novel tumor cell-autonomous suppressor role.
    Cancer Res. 2020 Apr 7. pii: 0008-5472.CAN-19-3018.
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  216. YANG L, So JY, Skrypek N, Yang HH, et al
    Induction of DNMT3B by PGE2 and IL6 at distant metastatic sites promotes epigenetic modification and breast cancer colonization.
    Cancer Res. 2020 Apr 7. pii: 0008-5472.CAN-19-3339.
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  217. HARNOSS JM, Le Thomas A, Reichelt M, Guttman O, et al
    IRE1alpha disruption in triple-negative breast cancer cooperates with anti-angiogenic therapy by reversing ER stress adaptation and remodeling the tumor microenvironment.
    Cancer Res. 2020 Apr 7. pii: 0008-5472.CAN-19-3108.
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  218. MARKER KM, Zavala VA, Vidaurre T, Lott PC, et al
    Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer Is Associated with Indigenous American Ancestry in Latin American Women.
    Cancer Res. 2020 Apr 3. pii: 0008-5472.CAN-19-3659.
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  219. HOLOWKO N, Eriksson M, Kuja-Halkola R, Azam S, et al
    Heritability of Mammographic Breast Density, Density Change, Microcalcifications, and Masses.
    Cancer Res. 2020;80:1590-1600.
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  220. SCHIPPER K, Drenth AP, van der Burg E, Cornelissen S, et al
    Truncated ASPP2 Drives Initiation and Progression of Invasive Lobular Carcinoma via Distinct Mechanisms.
    Cancer Res. 2020;80:1486-1497.
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  221. MEULEMANS L, Mesman RLS, Caputo SM, Krieger S, et al
    Skipping Nonsense to Maintain Function: The Paradigm of BRCA2 Exon 12.
    Cancer Res. 2020;80:1374-1386.
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  222. QIAO X, Liu Y, Prada ML, Mohan AK, et al
    UBR5 Is Coamplified with MYC in Breast Tumors and Encodes an Ubiquitin Ligase That Limits MYC-Dependent Apoptosis.
    Cancer Res. 2020;80:1414-1427.
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    March 2020
  223. MITOBE Y, Iino K, Takayama KI, Ikeda K, et al
    PSF promotes ER-positive breast cancer progression via posttranscriptional regulation of ESR1 and SCFD2.
    Cancer Res. 2020 Mar 25. pii: 0008-5472.CAN-19-3095.
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  224. FLACH KD, Periyasamy M, Jadhav A, Dorjsuren D, et al
    Endonuclease FEN1 coregulates ERalpha activity and provides a novel drug interface in tamoxifen resistant breast cancer.
    Cancer Res. 2020 Mar 19. pii: 0008-5472.CAN-19-2207.
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  225. ZHAO Y, Kaushik N, Kang JH, Kaushik NK, et al
    A Feedback loop comprising EGF/TGF-alpha Sustains TFCP2-mediated Breast Cancer Progression.
    Cancer Res. 2020 Mar 19. pii: 0008-5472.CAN-19-2908.
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  226. LUO ML, Zheng F, Chen W, Liang ZM, et al
    Inactivation of the prolyl isomerase Pin1 sensitizes BRCA1-proficient breast cancer to PARP inhibition.
    Cancer Res. 2020 Mar 19. pii: 0008-5472.CAN-19-2739.
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  227. MAJORINI MT, Cancila V, Rigoni A, Botti L, et al
    Infiltrating mast cell-mediated stimulation of estrogen receptor activity in breast cancer cells promotes the luminal phenotype.
    Cancer Res. 2020 Mar 16. pii: 0008-5472.CAN-19-3596.
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  228. SAMI E, Paul BT, Koziol JA, ElShamy WM, et al
    The Immunosuppressive Microenvironment in BRCA1-IRIS-Overexpressing TNBC Tumors Is Induced by Bidirectional Interaction with Tumor-Associated Macrophages.
    Cancer Res. 2020;80:1102-1117.
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  229. KARKI K, Wright GA, Mohankumar K, Jin UH, et al
    A Bis-Indole-Derived NR4A1 Antagonist Induces PD-L1 Degradation and Enhances Antitumor Immunity.
    Cancer Res. 2020;80:1011-1023.
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  230. BRINKER AE, Vivian CJ, Beadnell TC, Koestler DC, et al
    Mitochondrial Haplotype of the Host Stromal Microenvironment Alters Metastasis in a Non-cell Autonomous Manner.
    Cancer Res. 2020;80:1118-1129.
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    February 2020
  231. BORGES VF, Lyons TR, Germain D, Schedin P, et al
    Postpartum involution and cancer: an opportunity for targeted breast cancer prevention and treatments?
    Cancer Res. 2020 Feb 19. pii: 0008-5472.CAN-19-3448.
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  232. HEBERT JD, Myers SA, Naba A, Abbruzzese G, et al
    Proteomic profiling of the ECM of xenograft breast cancer metastases in different organs reveals distinct metastatic niches.
    Cancer Res. 2020 Feb 4. pii: 0008-5472.CAN-19-2961.
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    January 2020
  233. JANG JH, Kim DH, Lim JM, Lee JW, et al
    Breast cancer cell-derived soluble CD44 promotes tumor progression by triggering macrophage IL-1beta production.
    Cancer Res. 2020 Jan 22. pii: 0008-5472.CAN-19-2288.
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  234. ECKHARDT BL, Cao Y, Redfern AD, Chi LH, et al
    Activation of canonical BMP4-SMAD7 signaling suppresses breast cancer metastasis.
    Cancer Res. 2020 Jan 15. pii: 0008-5472.CAN-19-0743.
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  235. SANTORO AL, Drummond RD, da Silva IT, Ferreira SS, et al
    In situ DESI - MSI lipidomic profiles of breast cancer molecular subtypes and precursor lesions.
    Cancer Res. 2020 Jan 7. pii: 0008-5472.CAN-18-3574.
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  236. SANCHEZ-GONZALEZ I, Bobien A, Molnar C, Schmid S, et al
    miR-149 suppresses breast cancer metastasis by blocking paracrine interactions with macrophages.
    Cancer Res. 2020 Jan 7. pii: 0008-5472.CAN-19-1934.
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  237. NIU Y, Bao L, Chen Y, Wang C, et al
    HIF-2-induced long non-coding RNA RAB11B-AS1 promotes hypoxia-mediated angiogenesis and breast cancer metastasis.
    Cancer Res. 2020 Jan 3. pii: 0008-5472.CAN-19-1532.
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    December 2019
  238. CITRON F, Segatto I, Rampioni Vinciguerra GL, Musco L, et al
    Downregulation of miR-223 expression is an early event during mammary transformation and confers resistance to CDK4/6 inhibitors in luminal breast cancer.
    Cancer Res. 2019 Dec 20. pii: 0008-5472.CAN-19-1793.
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