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Articles published in
PLoS Comput Biol
    March 2026
  1. HUO X, Duan X, Huang X, Xue L, et al
    An integrative analysis reveals the mechanism of plastic stabilizers inducing breast cancer.
    PLoS Comput Biol. 2026;22:e1014025.
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  2. MORUNO-CUENCA A, Picart-Armada S, Bogle R, Fox J, et al
    singIST: An integrative method for comparative single-cell transcriptomics between disease models and humans.
    PLoS Comput Biol. 2026;22:e1014002.
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  3. SU JC, Lee CL, Yang FW, Chen YC, et al
    Network-based exploration of 4-(phenylsulfonyl)morpholine molecules for metastatic triple-negative breast cancer suppression.
    PLoS Comput Biol. 2026;22:e1014132.
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  4. DAVYDZENKA K, Caravagna G, Sanguinetti G
    Extending differential gene expression testing to handle genome aneuploidy in cancer.
    PLoS Comput Biol. 2026;22:e1014134.
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    February 2026
  5. WANG Y, Zang C, Li Z, Guo CC, et al
    A comparative study of statistical methods for identifying differentially expressed genes in spatial transcriptomics.
    PLoS Comput Biol. 2026;22:e1013956.
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    January 2026
  6. SANCERE L, Lorenz C, Helbig D, Persa OD, et al
    Histo-Miner: Deep learning based tissue features extraction pipeline from H&E whole slide images of cutaneous squamous cell carcinoma.
    PLoS Comput Biol. 2026;22:e1013907.
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  7. JI T, Yang B, Wang M, Ji H, et al
    AugGCL: Multimodal graph learning for spatial transcriptomics analysis with enhanced gene and morphological data.
    PLoS Comput Biol. 2026;22:e1013912.
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    December 2025
  8. HAN C, Song Z, Xu Z, Chen J, et al
    MAGNET: Multi-view graph autoencoder with cell-gene attention for cell interaction network reconstruction from spatial transcriptomics.
    PLoS Comput Biol. 2025;21:e1013810.
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    November 2025
  9. FAHMI NA, Cheng S, Overstreet J, Song Q, et al
    IPScan: Detecting novel intronic PolyAdenylation events with RNA-seq data.
    PLoS Comput Biol. 2025;21:e1013668.
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    October 2025
  10. MATACHE A, Lima-Junior JR, Kuznetsov M, Urbaniak K, et al
    Ligand discrimination in immune cells: Signal processing insights into immune dysfunction in ER+ breast cancer.
    PLoS Comput Biol. 2025;21:e1013615.
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    September 2025
  11. NOUIRA A, Azencott CA
    Sparse multitask group Lasso for genome-wide association studies.
    PLoS Comput Biol. 2025;21:e1012734.
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    August 2025
  12. YAVUZ BR, Sahin U, Jang H, Nussinov R, et al
    Mutations in tumor signaling, metastases, and synthetic lethality establish distinct patterns.
    PLoS Comput Biol. 2025;21:e1013351.
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    May 2025
  13. HOPFL S, Ozverin M, Nowack H, Tamas R, et al
    Integrated mathematical and experimental modeling uncovers enhanced EMT plasticity upon loss of the DLC1 tumor suppressor.
    PLoS Comput Biol. 2025;21:e1013076.
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    April 2025
  14. NOURBAKHSH M, Zheng Y, Noor H, Chen H, et al
    Revealing cancer driver genes through integrative transcriptomic and epigenomic analyses with Moonlight.
    PLoS Comput Biol. 2025;21:e1012999.
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  15. STAPLEY JN, Hamley JID, Basanez MG, Walker M, et al
    Modelling transmission thresholds and hypoendemic stability for onchocerciasis elimination.
    PLoS Comput Biol. 2025;21:e1013026.
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    February 2025
  16. SAKAI SA, Nomura R, Nagasawa S, Chi S, et al
    SpatialKNifeY (SKNY): Extending from spatial domain to surrounding area to identify microenvironment features with single-cell spatial omics data.
    PLoS Comput Biol. 2025;21:e1012854.
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  17. ZHAN X, Xu Q, Zheng Y, Lu G, et al
    Reliability-enhanced data cleaning in biomedical machine learning using inductive conformal prediction.
    PLoS Comput Biol. 2025;21:e1012803.
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    January 2025
  18. SHI X, Wang X, Jin L, Halakivi-Clarke L, et al
    Bayesian identification of differentially expressed isoforms using a novel joint model of RNA-seq data.
    PLoS Comput Biol. 2025;21:e1012750.
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    November 2024
  19. HUANG HY, Zhang FW, Yu J, Xiao YH, et al
    A computational analysis of the oncogenic and anti-tumor immunity role of P4HA3 in human cancers.
    PLoS Comput Biol. 2024;20:e1012284.
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    October 2024
  20. CHEN L, Huang ZH, Sun Y, Domaratzki M, et al
    Conditional probabilistic diffusion model driven synthetic radiogenomic applications in breast cancer.
    PLoS Comput Biol. 2024;20:e1012490.
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    September 2024
  21. SYLLA A, Chevillon C, Djidjiou-Demasse R, Seydi O, et al
    Understanding the transmission of bacterial agents of sapronotic diseases using an ecosystem-based approach: A first spatially realistic metacommunity model.
    PLoS Comput Biol. 2024;20:e1012435.
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    July 2024
  22. NEVAREZ AJ, Mudla A, Diaz SA, Hao N, et al
    Using deep learning to decipher the impact of telomerase promoter mutations on the dynamic metastatic morpholome.
    PLoS Comput Biol. 2024;20:e1012271.
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    June 2024
  23. XIE X, Sinha S
    Quantitative estimates of the regulatory influence of long non-coding RNAs on global gene expression variation using TCGA breast cancer transcriptomic data.
    PLoS Comput Biol. 2024;20:e1012103.
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  24. VANDERDOES J, Marceaux C, Yokote K, Asselin-Labat ML, et al
    Using random forests to uncover the predictive power of distance-varying cell interactions in tumor microenvironments.
    PLoS Comput Biol. 2024;20:e1011361.
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  25. DIMITRIOU NM, Flores-Torres S, Kyriakidou M, Kinsella JM, et al
    Cancer cell sedimentation in 3D cultures reveals active migration regulated by self-generated gradients and adhesion sites.
    PLoS Comput Biol. 2024;20:e1012112.
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  26. PERRONE MC, Lerner MG, Dunworth M, Ewald AJ, et al
    Prioritizing drug targets by perturbing biological network response functions.
    PLoS Comput Biol. 2024;20:e1012195.
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    May 2024
  27. BENZEKRY S, Mastri M, Nicolo C, Ebos JML, et al
    Machine-learning and mechanistic modeling of metastatic breast cancer after neoadjuvant treatment.
    PLoS Comput Biol. 2024;20:e1012088.
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    April 2024
  28. LIU C, Xiao K, Yu C, Lei Y, et al
    A probabilistic knowledge graph for target identification.
    PLoS Comput Biol. 2024;20:e1011945.
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    March 2024
  29. VALEGA-MACKENZIE W, Rodriguez Messan M, Yogurtcu ON, Nukala U, et al
    Dose optimization of an adjuvanted peptide-based personalized neoantigen melanoma vaccine.
    PLoS Comput Biol. 2024;20:e1011247.
    >> Share


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