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Sepsis

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Articles published in
Proc Natl Acad Sci U S A
    March 2024
  1. OAMI T, Abtahi S, Shimazui T, Chen CW, et al
    Claudin-2 upregulation enhances intestinal permeability, immune activation, dysbiosis, and mortality in sepsis.
    Proc Natl Acad Sci U S A. 2024;121:e2217877121.
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    January 2024
  2. HULLAHALLI K, Dailey KG, Hasegawa Y, Johnson WE, et al
    Reverse transcriptase inhibitors prevent liver abscess formation during Escherichia coli bloodstream infection.
    Proc Natl Acad Sci U S A. 2024;121:e2319162121.
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  3. PARSONS JB, Sidders AE, Velez AZ, Hanson BM, et al
    In-patient evolution of a high-persister Escherichia coli strain with reduced in vivo antibiotic susceptibility.
    Proc Natl Acad Sci U S A. 2024;121:e2314514121.
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  4. KANG S, Onishi S, Ling Z, Inoue H, et al
    Gp130-HIF1alpha axis-induced vascular damage is prevented by the short-term inhibition of IL-6 receptor signaling.
    Proc Natl Acad Sci U S A. 2024;121:e2315898120.
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    July 2023
  5. SHRESTHA N, Zorn-Pauly K, Mesirca P, Koyani CN, et al
    Lipopolysaccharide-induced sepsis impairs M2R-GIRK signaling in the mouse sinoatrial node.
    Proc Natl Acad Sci U S A. 2023;120:e2210152120.
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    May 2023
  6. GOLDBERG BS, Spencer DA, Pandey S, Ordonez T, et al
    Complement contributes to antibody-mediated protection against repeated SHIV challenge.
    Proc Natl Acad Sci U S A. 2023;120:e2221247120.
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    March 2023
  7. ETEMAD B, Sun X, Li Y, Melberg M, et al
    HIV post-treatment controllers have distinct immunological and virological features.
    Proc Natl Acad Sci U S A. 2023;120:e2218960120.
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    January 2023
  8. LIAO YE, Xu Y, Arnold K, Zhang F, et al
    Using heparan sulfate octadecasaccharide (18-mer) as a multi-target agent to protect against sepsis.
    Proc Natl Acad Sci U S A. 2023;120:e2209528120.
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  9. MORITA M, Yoneda A, Tokunoh N, Masaki T, et al
    Upregulation of Robo4 expression by SMAD signaling suppresses vascular permeability and mortality in endotoxemia and COVID-19 models.
    Proc Natl Acad Sci U S A. 2023;120:e2213317120.
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  10. O'BOYLE N, Douce GR, Farrell G, Rattray NJW, et al
    Distinct ecological fitness factors coordinated by a conserved Escherichia coli regulator during systemic bloodstream infection.
    Proc Natl Acad Sci U S A. 2023;120:e2212175120.
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    October 2022
  11. CHENG M, Xu J, Ding K, Zhang J, et al
    Attenuation of relapsing fever neuroborreliosis in mice by IL-17A blockade.
    Proc Natl Acad Sci U S A. 2022;119:e2205460119.
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  12. GANGULI A, Lim J, Mostafa A, Saavedra C, et al
    A culture-free biphasic approach for sensitive and rapid detection of pathogens in dried whole-blood matrix.
    Proc Natl Acad Sci U S A. 2022;119:e2209607119.
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    August 2022
  13. LEISMAN DE, Privratsky JR, Lehman JR, Abraham MN, et al
    Angiotensin II enhances bacterial clearance via myeloid signaling in a murine sepsis model.
    Proc Natl Acad Sci U S A. 2022;119:e2211370119.
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  14. VELU V, Titanji K, Ahmed H, Shetty RD, et al
    PD-1 blockade following ART interruption enhances control of pathogenic SIV in rhesus macaques.
    Proc Natl Acad Sci U S A. 2022;119:e2202148119.
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  15. ZWACK EE, Chen Z, Devlin JC, Li Z, et al
    Staphylococcus aureus induces a muted host response in human blood that blunts the recruitment of neutrophils.
    Proc Natl Acad Sci U S A. 2022;119:e2123017119.
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    June 2022
  16. SIEWERT LK, Korotaev A, Sedzicki J, Fromm K, et al
    Identification of the Bartonella autotransporter CFA as a protective antigen and hypervariable target of neutralizing antibodies in mice.
    Proc Natl Acad Sci U S A. 2022;119:e2202059119.
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    May 2022
  17. HUANG J, Ita M, Zhou H, Zhao H, et al
    Autophagy induced by taurolidine protects against polymicrobial sepsis by promoting both host resistance and disease tolerance.
    Proc Natl Acad Sci U S A. 2022;119:e2121244119.
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    March 2022
  18. BERGMANN CB, McReynolds CB, Wan D, Singh N, et al
    sEH-derived metabolites of linoleic acid drive pathologic inflammation while impairing key innate immune cell function in burn injury.
    Proc Natl Acad Sci U S A. 2022;119:e2120691119.
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  19. OCHOA GAUTIER JB
    Dietary modification of myeloid-derived suppressor cells (MDSC) activity in sepsis.
    Proc Natl Acad Sci U S A. 2022;119:e2201396119.
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    February 2022
  20. REIZINE F, Gregoire M, Lesouhaitier M, Coirier V, et al
    Beneficial effects of citrulline enteral administration on sepsis-induced T cell mitochondrial dysfunction.
    Proc Natl Acad Sci U S A. 2022;119.
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  21. ISHIYAMA K, Arakawa-Hoyt J, Aguilar OA, Damm I, et al
    Mass cytometry reveals single-cell kinetics of cytotoxic lymphocyte evolution in CMV-infected renal transplant patients.
    Proc Natl Acad Sci U S A. 2022;119.
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  22. TUFFS SW, Goncheva MI, Xu SX, Craig HC, et al
    Superantigens promote Staphylococcus aureus bloodstream infection by eliciting pathogenic interferon-gamma production.
    Proc Natl Acad Sci U S A. 2022;119.
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    January 2022

  23. Correction to Supporting Information for Chen et al., Increased gene copy number of DEFA1/DEFA3 worsens sepsis by inducing endothelial pyroptosis.
    Proc Natl Acad Sci U S A. 2022;119.
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    November 2021
  24. WICHE SALINAS TR, Zhang Y, Sarnello D, Zhyvoloup A, et al
    Th17 cell master transcription factor RORC2 regulates HIV-1 gene expression and viral outgrowth.
    Proc Natl Acad Sci U S A. 2021;118.
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    September 2021
  25. KESHARI RS, Popescu NI, Silasi R, Regmi G, et al
    Complement C5 inhibition protects against hemolytic anemia and acute kidney injury in anthrax peptidoglycan-induced sepsis in baboons.
    Proc Natl Acad Sci U S A. 2021;118.
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    July 2021
  26. ZHANG F, Qi L, Feng Q, Zhang B, et al
    HIPK2 phosphorylates HDAC3 for NF-kappaB acetylation to ameliorate colitis-associated colorectal carcinoma and sepsis.
    Proc Natl Acad Sci U S A. 2021;118.
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  27. MAITI G, Frikeche J, Lam CY, Biswas A, et al
    Matrix lumican endocytosed by immune cells controls receptor ligand trafficking to promote TLR4 and restrict TLR9 in sepsis.
    Proc Natl Acad Sci U S A. 2021;118.
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    April 2021
  28. KWON WY, Suh GJ, Jung YS, Park SM, et al
    Circulating mitochondrial N-formyl peptides contribute to secondary nosocomial infection in patients with septic shock.
    Proc Natl Acad Sci U S A. 2021;118.
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    March 2021
  29. SIDDIQUI SS, Dhar C, Sundaramurthy V, Sasmal A, et al
    Sialoglycan recognition is a common connection linking acidosis, zinc, and HMGB1 in sepsis.
    Proc Natl Acad Sci U S A. 2021;118.
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  30. CHANG YL, Rossetti M, Gjertson DW, Rubbi L, et al
    Human DNA methylation signatures differentiate persistent from resolving MRSA bacteremia.
    Proc Natl Acad Sci U S A. 2021;118.
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    February 2021
  31. VOLLMERS AC, Covarrubias S, Kuang D, Shulkin A, et al
    A conserved long noncoding RNA, GAPLINC, modulates the immune response during endotoxic shock.
    Proc Natl Acad Sci U S A. 2021;118.
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  32. HE X, Dong K, Shen J, Hu G, et al
    Deficiency of the novel high mobility group protein HMGXB4 protects against systemic inflammation-induced endotoxemia in mice.
    Proc Natl Acad Sci U S A. 2021;118.
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    January 2021
  33. HOU P, Jia P, Yang K, Li Z, et al
    An unconventional role of an ASB family protein in NF-kappaB activation and inflammatory response during microbial infection and colitis.
    Proc Natl Acad Sci U S A. 2021;118.
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    December 2020
  34. ZHONG W, Shi Z, Mahadevegowda SH, Liu B, et al
    Designer broad-spectrum polyimidazolium antibiotics.
    Proc Natl Acad Sci U S A. 2020;117:31376-31385.
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    November 2020
  35. KRESSEL AM, Tsaava T, Levine YA, Chang EH, et al
    Identification of a brainstem locus that inhibits tumor necrosis factor.
    Proc Natl Acad Sci U S A. 2020;117:29803-29810.
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    October 2020
  36. SWANSON L, Katkar GD, Tam J, Pranadinata RF, et al
    TLR4 signaling and macrophage inflammatory responses are dampened by GIV/Girdin.
    Proc Natl Acad Sci U S A. 2020;117:26895-26906.
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  37. SILVA ON, Torres MDT, Cao J, Alves ESF, et al
    Repurposing a peptide toxin from wasp venom into antiinfectives with dual antimicrobial and immunomodulatory properties.
    Proc Natl Acad Sci U S A. 2020;117:26936-26945.
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