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Articles published in
Intensive Care Med
    April 2024
  1. CHAI MG, Tu Q, Cotta MO, Bauer MJ, et al
    Correction: Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis.
    Intensive Care Med. 2024 Apr 2. doi: 10.1007/s00134-024-07393.
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  2. ZHAO Y, Zang B, Wang Q
    The effectiveness of alkaline phosphatase in sepsis-associated acute kidney injury.
    Intensive Care Med. 2024 Apr 2. doi: 10.1007/s00134-024-07392.
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  3. HERNANDEZ G, Carmona P, Ait-Oufella H
    Monitoring capillary refill time in septic shock.
    Intensive Care Med. 2024;50:580-582.
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  4. KATTAN E, Ibarra-Estrada M, Jung C
    Knowing the ropes of vasopressor dosing: a focus on norepinephrine.
    Intensive Care Med. 2024;50:587-589.
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    March 2024
  5. CHAI GG, Tu Q, Cotta MO, Bauer MJ, et al
    Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis.
    Intensive Care Med. 2024 Mar 13. doi: 10.1007/s00134-024-07353.
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  6. PICKKERS P, Angus DC, Bass K, Bellomo R, et al
    Correction: Phase-3 trial of recombinant human alkaline phosphatase for patients with sepsis-associated acute kidney injury (REVIVAL).
    Intensive Care Med. 2024 Mar 4. doi: 10.1007/s00134-024-07357.
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  7. AHLSTROM B, Larsson IM, Strandberg G, Lipcsey M, et al
    Association of sepsis with long-term mortality and causes of death in the Swedish intensive care cohort.
    Intensive Care Med. 2024 Mar 4. doi: 10.1007/s00134-024-07370.
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  8. DE BACKER D, Hajjar L, Monnet X
    Vasoconstriction in septic shock.
    Intensive Care Med. 2024;50:459-462.
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  9. KREITMANN L, Helms J, Martin-Loeches I, Salluh J, et al
    ICU-acquired infections in immunocompromised patients.
    Intensive Care Med. 2024;50:332-349.
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    January 2024
  10. PROWLE JR, Bagshaw SM, Forni LG
    Tackling sepsis-associated AKI: are there any chances of REVIVAL with new approaches?
    Intensive Care Med. 2024 Jan 10. doi: 10.1007/s00134-023-07294.
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  11. PICKKERS P, Angus DC, Bass K, Bellomo R, et al
    Phase-3 trial of recombinant human alkaline phosphatase for patients with sepsis-associated acute kidney injury (REVIVAL).
    Intensive Care Med. 2024 Jan 3. doi: 10.1007/s00134-023-07271.
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  12. ZAMPIERI FG, Machado FR, Veiga VC, Azevedo LCP, et al
    Determinants of fluid use and the association between volume of fluid used and effect of balanced solutions on mortality in critically ill patients: a secondary analysis of the BaSICS trial.
    Intensive Care Med. 2024;50:79-89.
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    November 2023
  13. BALIK M, Maly M, Brozek T, Rulisek J, et al
    Propafenone versus amiodarone for supraventricular arrhythmias in septic shock: a randomised controlled trial.
    Intensive Care Med. 2023;49:1283-1292.
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    October 2023
  14. FOWLER C, Scordo M, Chawla S
    The EAS(E)IX of predicting sepsis after allogeneic hematopoietic cell transplantation.
    Intensive Care Med. 2023 Oct 24. doi: 10.1007/s00134-023-07242.
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  15. VAN AMSTEL RBE, Kennedy JN, Scicluna BP, Bos LDJ, et al
    Uncovering heterogeneity in sepsis: a comparative analysis of subphenotypes.
    Intensive Care Med. 2023 Oct 18. doi: 10.1007/s00134-023-07239.
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  16. ZHANG Z, Chen L, Liu X, Yang J, et al
    Exploring disease axes as an alternative to distinct clusters for characterizing sepsis heterogeneity.
    Intensive Care Med. 2023 Oct 4. doi: 10.1007/s00134-023-07226.
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    September 2023
  17. WHITE KC, Laupland KB, Tabah A, Ramanan M, et al
    Details and the devil within: the case of sepsis associated AKI. Author's reply.
    Intensive Care Med. 2023 Sep 10. doi: 10.1007/s00134-023-07209.
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    August 2023
  18. GOMEZ H, Zarbock A
    Details and the devil within - the case of sepsis associated acute kidney injury.
    Intensive Care Med. 2023 Aug 31. doi: 10.1007/s00134-023-07204.
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  19. WHITE KC, Laupland KB, Tabah A, Ramanan M, et al
    Clinical implications of urine output-based sepsis-associated acute kidney injury. Author's reply.
    Intensive Care Med. 2023 Aug 28. doi: 10.1007/s00134-023-07205.
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  20. CLAURE-DEL GRANADO R, James MT, Legrand M
    Tackling sepsis-associated acute kidney injury using routinely collected data.
    Intensive Care Med. 2023 Aug 28. doi: 10.1007/s00134-023-07200.
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  21. GIAMARELLOS-BOURBOULIS EJ, Zinkernagel AS, De Robertis E, Azoulay E, et al
    Correction: Sepsis, a call for inclusion in the work plan of the European Center for Disease Prevention and Control.
    Intensive Care Med. 2023 Aug 24. doi: 10.1007/s00134-023-07197.
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  22. KORELL F, DeFilipp Z, Schreck N, Luft T, et al
    Validation of pre-conditioning EASIX for prediction of sepsis after allogeneic stem cell transplantation.
    Intensive Care Med. 2023 Aug 23. doi: 10.1007/s00134-023-07193.
    >> Share

  23. KASUGAI D, Nakashima T, Goto T
    Clinical implications of urine output-based sepsis-associated acute kidney injury.
    Intensive Care Med. 2023 Aug 21. doi: 10.1007/s00134-023-07190.
    >> Share

  24. GIAMARELLOS-BOURBOULIS EJ, Zinkernagel AS, De Robertis E, Azoulay E, et al
    Sepsis, a call for inclusion in the work plan of the European Center for Disease Prevention and Control.
    Intensive Care Med. 2023 Aug 1. doi: 10.1007/s00134-023-07127.
    >> Share

    July 2023
  25. REILLY JP, Zhao Z, Shashaty MGS, Koyama T, et al
    Exposure to ambient air pollutants and acute respiratory distress syndrome risk in sepsis.
    Intensive Care Med. 2023 Jul 20. doi: 10.1007/s00134-023-07148.
    >> Share

  26. WHITE KC, Serpa-Neto A, Hurford R, Clement P, et al
    Sepsis-associated acute kidney injury in the intensive care unit: incidence, patient characteristics, timing, trajectory, treatment, and associated outcomes. A multicenter, observational study.
    Intensive Care Med. 2023 Jul 11. doi: 10.1007/s00134-023-07138.
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  27. KJAER MN, Meyhoff TS, Sivapalan P, Granholm A, et al
    Long-term effects of restriction of intravenous fluid in adult ICU patients with septic shock.
    Intensive Care Med. 2023;49:820-830.
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    June 2023
  28. ZHANG C, Zhang X, Sun Z, Liu X, et al
    MetaSepsisBase: a biomarker database for systems biological analysis and personalized diagnosis of heterogeneous human sepsis.
    Intensive Care Med. 2023 Jun 17. doi: 10.1007/s00134-023-07126.
    >> Share

  29. BRUNO RR, Wollborn J, Fengler K, Flick M, et al
    Direct assessment of microcirculation in shock: a randomized-controlled multicenter study.
    Intensive Care Med. 2023;49:645-655.
    >> Share

    April 2023
  30. BOLDT J, Muller M, Kuhn D, Linke LC, et al
    Retraction Note: Circulating adhesion molecules in the critically ill: A comparison between trauma and sepsis patients.
    Intensive Care Med. 2023 Apr 4. doi: 10.1007/s00134-023-07055.
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    February 2023
  31. MATCHETT G, Moon TS, Stewart JW, Liang L, et al
    Etomidate for endotracheal intubation in sepsis. Author's reply.
    Intensive Care Med. 2023 Feb 23. doi: 10.1007/s00134-023-06987.
    >> Share

  32. TABAH A, Buetti N, Staiquly Q, Ruckly S, et al
    Epidemiology and outcomes of hospital-acquired bloodstream infections in intensive care unit patients: the EUROBACT-2 international cohort study.
    Intensive Care Med. 2023 Feb 10:1-13. doi: 10.1007/s00134-022-06944.
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    January 2023
  33. KALIMOUTTOU A, Pirracchio R
    Database-based machine learning in sepsis deserves attention. Author's reply.
    Intensive Care Med. 2023 Jan 10. doi: 10.1007/s00134-022-06972.
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  34. MOHR NM, Faine B
    Etomidate for endotracheal intubation in sepsis.
    Intensive Care Med. 2023 Jan 4. doi: 10.1007/s00134-022-06962.
    >> Share

  35. HU W, Yang M, Chen H
    Database-based machine learning in sepsis deserves attention.
    Intensive Care Med. 2023 Jan 2. doi: 10.1007/s00134-022-06961.
    >> Share

  36. POVOA P, Coelho L, Dal-Pizzol F, Ferrer R, et al
    How to use biomarkers of infection or sepsis at the bedside: guide to clinicians.
    Intensive Care Med. 2023 Jan 2:1-12. doi: 10.1007/s00134-022-06956.
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    November 2022
  37. KALIMOUTTOU A, Lerner I, Cheurfa C, Jannot AS, et al
    Machine-learning-derived sepsis bundle of care.
    Intensive Care Med. 2022 Nov 29. doi: 10.1007/s00134-022-06928.
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  38. DE PASCALE G, Antonelli M, Deschepper M, Arvaniti K, et al
    Poor timing and failure of source control are risk factors for mortality in critically ill patients with secondary peritonitis.
    Intensive Care Med. 2022;48:1593-1606.
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    September 2022
  39. BHAVANI SV, Semler M, Qian ET, Verhoef PA, et al
    Development and validation of novel sepsis subphenotypes using trajectories of vital signs.
    Intensive Care Med. 2022 Sep 24. pii: 10.1007/s00134-022-06890.
    >> Share

  40. COUR M, Klouche K, Souweine B, Quenot JP, et al
    Remote ischemic conditioning in septic shock: the RECO-Sepsis randomized clinical trial.
    Intensive Care Med. 2022 Sep 14. pii: 10.1007/s00134-022-06872.
    >> Share

  41. RUSSELL JA, Meyer NJ, Walley KR
    Use of Mendelian randomization to better understand and treat sepsis.
    Intensive Care Med. 2022 Sep 14. pii: 10.1007/s00134-022-06778.
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  42. DE WAELE JJ, Girardis M, Martin-Loeches I
    Source control in the management of sepsis and septic shock.
    Intensive Care Med. 2022 Sep 14. pii: 10.1007/s00134-022-06852.
    >> Share

    August 2022
  43. YOUNG PJ, Lamontagne F, Fujii T
    Vitamin C in sepsis.
    Intensive Care Med. 2022 Aug 12. pii: 10.1007/s00134-022-06822.
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    July 2022
  44. LUKASZEWSKI RA, Jones HE, Gersuk VH, Russell P, et al
    Presymptomatic diagnosis of postoperative infection and sepsis using gene expression signatures.
    Intensive Care Med. 2022 Jul 13. pii: 10.1007/s00134-022-06769.
    >> Share

    June 2022
  45. BLOOS F, Held J, Kluge S, Simon P, et al
    (1 --> 3)-beta-D-Glucan-guided antifungal therapy in adults with sepsis: the CandiSep randomized clinical trial.
    Intensive Care Med. 2022 Jun 16. pii: 10.1007/s00134-022-06733.
    3)-beta-D-Glucan-guided antifungal therapy in adults with sepsis: the CandiSep randomized clinical trial.&body=BLOOS F, Held J, Kluge S, Simon P, et al. (1 --> 3)-beta-D-Glucan-guided antifungal therapy in adults with sepsis: the CandiSep randomized clinical trial. Intensive Care Med. 2022 Jun 16. pii: 10.1007/s00134-022-06733. https://www.ncbi.nlm.nih.gov/m/pubmed/35708758" ALT="Email" TITLE="Email"> --> >> Share

  46. MEYNAAR IA, van Rijn S, Ottens TH, van Burgel ND, et al
    Increased risk of central line-associated bloodstream infection in COVID-19 patients associated with dexamethasone but not with interleukin antagonists.
    Intensive Care Med. 2022 Jun 7. pii: 10.1007/s00134-022-06750.
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    April 2022
  47. KORELL F, Schreck N, Muller-Tidow C, Dreger P, et al
    Pre-transplant EASIX and sepsis after allogeneic stem cell transplantation.
    Intensive Care Med. 2022 Apr 16. pii: 10.1007/s00134-022-06676.
    >> Share

  48. TRAN A, Fernando SM, Rochwerg B, Seymour CW, et al
    Characterizing systematic challenges in sample size determination for sepsis trials.
    Intensive Care Med. 2022 Apr 12. pii: 10.1007/s00134-022-06691.
    >> Share

  49. POOLE D, D'Arrigo S
    Coupled plasma filtration and adsorption for the treatment of septic shock.
    Intensive Care Med. 2022;48:493-495.
    >> Share

    March 2022
  50. BUIL JB, Schouten JA, Wauters J, van de Hoeven H, et al
    Absence of candidemia in critically ill patients with COVID-19 receiving selective digestive decontamination.
    Intensive Care Med. 2022 Mar 22. pii: 10.1007/s00134-022-06651.
    >> Share

  51. HAGEL S, Bach F, Brenner T, Bracht H, et al
    Correction to: Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis: a randomized controlled trial.
    Intensive Care Med. 2022 Mar 18. pii: 10.1007/s00134-022-06668.
    >> Share

  52. GIJSEN M, Dreesen E, Wauters J, Debaveye Y, et al
    The TARGET trial as a plea for model-informed precision dosing of piperacillin/tazobactam in patients with sepsis.
    Intensive Care Med. 2022 Mar 17. pii: 10.1007/s00134-022-06679.
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  53. HAGEL S, Pletz MW, Lehmann T
    Concerns about study design and suggestion of additional analysis of therapeutic drug monitoring-guided piperacillin/tazobactam therapy for patients with sepsis. Author's reply.
    Intensive Care Med. 2022 Mar 15. pii: 10.1007/s00134-022-06669.
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    February 2022
  54. YOSHIHIRO S, Taito S
    Concerns about study design and suggestion of additional analysis of therapeutic drug monitoring-guided piperacillin/tazobactam therapy for patients with sepsis.
    Intensive Care Med. 2022 Feb 18. pii: 10.1007/s00134-022-06648.
    >> Share

  55. ZHANG S, Li B, Yi S, He Z, et al
    Goal-directed therapy in sepsis strikes back. Author's reply.
    Intensive Care Med. 2022 Feb 14. pii: 10.1007/s00134-022-06633.
    >> Share

  56. ANGRIMAN F, Rosella LC, Lawler PR, Ko DT, et al
    Sepsis hospitalization and risk of subsequent cardiovascular events in adults: a population-based matched cohort study.
    Intensive Care Med. 2022 Feb 10. pii: 10.1007/s00134-022-06634.
    >> Share

  57. HAGEL S, Bach F, Brenner T, Bracht H, et al
    Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis: a randomized controlled trial.
    Intensive Care Med. 2022 Feb 1. pii: 10.1007/s00134-021-06609.
    >> Share

  58. BAKKER J, Kattan E, Annane D, Castro R, et al
    Current practice and evolving concepts in septic shock resuscitation.
    Intensive Care Med. 2022;48:148-163.
    >> Share

    January 2022
  59. CHEN HH, Lin CH, Wu CL, Chao WC, et al
    Incidence and risk factors of mental illness among the spouses of patients with sepsis: a population-based cohort study.
    Intensive Care Med. 2022 Jan 25. pii: 10.1007/s00134-022-06624.
    >> Share

  60. YU K, Zhang S, Chen N, Chen M, et al
    Critical care ultrasound goal-directed versus early goal-directed therapy in septic shock.
    Intensive Care Med. 2022;48:121-123.
    >> Share

    December 2021
  61. PETERS-SENGERS H, Butler JM, Uhel F, Schultz MJ, et al
    Source-specific host response and outcomes in critically ill patients with sepsis: a prospective cohort study.
    Intensive Care Med. 2021 Dec 13. pii: 10.1007/s00134-021-06574.
    >> Share

    November 2021
  62. FUJII T, Salanti G, Belletti A, Bellomo R, et al
    Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis.
    Intensive Care Med. 2021 Nov 9. pii: 10.1007/s00134-021-06558.
    >> Share

  63. SKURZAK S, Gallo M, Lavezzo B, Iannandrea S, et al
    Goal-directed therapy in sepsis strikes back.
    Intensive Care Med. 2021 Nov 8. pii: 10.1007/s00134-021-06569.
    >> Share

  64. LATERRE PF, Pickkers P, Marx G, Wittebole X, et al
    Safety and tolerability of non-neutralizing adrenomedullin antibody adrecizumab (HAM8101) in septic shock patients: the AdrenOSS-2 phase 2a biomarker-guided trial.
    Intensive Care Med. 2021;47:1284-1294.
    >> Share

  65. GARBERO E, Livigni S, Ferrari F, Finazzi S, et al
    High dose coupled plasma filtration and adsorption in septic shock patients. Results of the COMPACT-2: a multicentre, adaptive, randomised clinical trial.
    Intensive Care Med. 2021;47:1303-1311.
    >> Share

  66. WENDEL GARCIA PD, Hilty MP, Held U, Kleinert EM, et al
    Cytokine adsorption in severe, refractory septic shock.
    Intensive Care Med. 2021;47:1334-1336.
    >> Share

    October 2021
  67. STAHL K, Wendel-Garcia PD, Bode C, David S, et al
    Unraveling the secret of re-balancing homeostasis in sepsis: a critical view on extracorporeal blood purification modalities.
    Intensive Care Med. 2021 Oct 28. pii: 10.1007/s00134-021-06560.
    >> Share

  68. SATO R, Hasegawa D, Dugar S
    Do we have sufficient evidence to support the use of inotropes in patients with sepsis?
    Intensive Care Med. 2021 Oct 26. pii: 10.1007/s00134-021-06564.
    >> Share

  69. EVANS L, Rhodes A, Alhazzani W, Antonelli M, et al
    Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021.
    Intensive Care Med. 2021 Oct 2. pii: 10.1007/s00134-021-06506.
    >> Share

    September 2021
  70. LIEBCHEN U, Scharf C, Zoller M, Weinelt F, et al
    No clinically relevant removal of meropenem by cytokine adsorber CytoSorb((R)) in critically ill patients with sepsis or septic shock.
    Intensive Care Med. 2021 Sep 14. pii: 10.1007/s00134-021-06487.
    >> Share

  71. COHEN J, Blumenthal A, Cuellar-Partida G, Evans DM, et al
    The relationship between adrenocortical candidate gene expression and clinical response to hydrocortisone in patients with septic shock.
    Intensive Care Med. 2021;47:974-983.
    >> Share

    August 2021
  72. SWEENEY TE, Wong HR
    Transcriptional markers in response to hydrocortisone in sepsis in ADRENAL: a step toward precision medicine.
    Intensive Care Med. 2021 Aug 10. pii: 10.1007/s00134-021-06504.
    >> Share

  73. KOSYAKOVSKY LB, Angriman F, Katz E, Adhikari NK, et al
    Association between sepsis survivorship and long-term cardiovascular outcomes in adults: a systematic review and meta-analysis.
    Intensive Care Med. 2021 Aug 9. pii: 10.1007/s00134-021-06479.
    >> Share

    July 2021

  74. Monocyte distribution width as a biomarker of resistance to corticosteroids in patients with sepsis: the MOCORSEP observational study.
    Intensive Care Med. 2021 Jul 27. pii: 10.1007/s00134-021-06478.
    >> Share


  75. Reducing the global burden of sepsis: a positive legacy for the COVID-19 pandemic?
    Intensive Care Med. 2021;47:733-736.
    >> Share

    May 2021
  76. LITTON E, Currie A, Raby E
    Probiotics and sepsis: separating the signal from the noise.
    Intensive Care Med. 2021 May 20. pii: 10.1007/s00134-021-06427.
    >> Share

    March 2021
  77. PELLEGRINI JAS, Schwarz P, Parolo E, Cremonese RV, et al
    All that glitters is not gold: an unusual presentation of S. aureus sepsis during ECMO.
    Intensive Care Med. 2021 Mar 21. pii: 10.1007/s00134-021-06366.
    >> Share

  78. DAVID S, Bode C, Putensen C, Welte T, et al
    Adjuvant therapeutic plasma exchange in septic shock.
    Intensive Care Med. 2021;47:352-354.
    >> Share

    February 2021
  79. THOMPSON K, Venkatesh B, Hammond N, Taylor C, et al
    Sex differences in response to adjunctive corticosteroid treatment for patients with septic shock.
    Intensive Care Med. 2021;47:246-248.
    >> Share

    January 2021
  80. BUETTI N, Ruckly S, de Montmollin E, Reignier J, et al
    COVID-19 increased the risk of ICU-acquired bloodstream infections: a case-cohort study from the multicentric OUTCOMEREA network.
    Intensive Care Med. 2021 Jan 27. pii: 10.1007/s00134-021-06346.
    >> Share

    July 2020
  81. AURIEMMA CL, Delucchi K, Liu KD, Calfee CS, et al
    The attributable mortality of acute respiratory distress syndrome.
    Intensive Care Med. 2020;46:1510-1511.
    >> Share

  82. DE GROOTH HJ, Tuinman PR, Girbes ARJ
    The attributable mortality of acute respiratory distress syndrome.
    Intensive Care Med. 2020;46:1508-1509.
    >> Share

    February 2020
  83. TIMSIT JF, Ruppe E, Barbier F, Tabah A, et al
    Bloodstream infections in critically ill patients: an expert statement.
    Intensive Care Med. 2020;46:266-284.
    >> Share

  84. RELLO J, Campogiani L, Eshwara VK
    Understanding resistance in enterococcal infections.
    Intensive Care Med. 2020;46:353-356.
    >> Share

    January 2020
  85. ROIMI M, Neuberger A, Shrot A, Paul M, et al
    Early diagnosis of bloodstream infections in the intensive care unit using machine-learning algorithms.
    Intensive Care Med. 2020 Jan 7. pii: 10.1007/s00134-019-05876.
    >> Share


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