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Schizophrenia

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Articles published in
Biol Psychiatry
    November 2025
  1. FLETCHER PC, Robbins TW
    Shining a Light on the Earliest Symptoms of Psychosis.
    Biol Psychiatry. 2025;98:652-653.
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  2. LEE CH
    Pleiotropy in Multitrait Genome-Wide Association Studies: Approaches and Insights From Schizophrenia-Cognition Analyses.
    Biol Psychiatry. 2025;98:650-651.
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  3. POLLAK TA
    Autoimmune Psychosis: Progress, Problems, and the Path Ahead.
    Biol Psychiatry. 2025;98:648-649.
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    October 2025
  4. HOWES OD, Vano LJ, Petty AE, Rutigliano G, et al
    The trace amine-associated receptor 1 regulates presynaptic dopamine function: evidence from preclinical studies and a phase 1b trial in patients with schizophrenia.
    Biol Psychiatry. 2025 Oct 21:S0006-3223(25)01533.
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  5. MEMETOGLU O, Du F, Chouinard VA, Ongur D, et al
    Reductive Stress and Dysregulated Energy Metabolism in Schizophrenia: Mechanisms and Therapeutic Targets.
    Biol Psychiatry. 2025 Oct 16:S0006-3223(25)01528.
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  6. MA Y, Girdhar K, Hoffman GE, Fullard JF, et al
    Sex differences in brain cell-type specific chromatin accessibility in schizophrenia.
    Biol Psychiatry. 2025 Oct 8:S0006-3223(25)01517.
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    September 2025
  7. BRAH HS, Sran N, Sanghani S, Valmadrid L, et al
    Clinical Genetic Testing in Schizophrenia: A Systematic Review and Meta-Analysis.
    Biol Psychiatry. 2025 Sep 30:S0006-3223(25)01485.
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  8. MOLLON J, Schultz LM, Knowles EEM, Jacquemont S, et al
    Low Stability and Specificity of Polygenic Risk Scores for Major Psychiatric Disorders Limit Their Clinical Utility.
    Biol Psychiatry. 2025;98:476-484.
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  9. WANG SH, Feng YA, Lin MC, Cheng CF, et al
    Incorporating Polygenic Liability and Family History for Predicting Psychiatric Diseases in the Taiwan Biobank.
    Biol Psychiatry. 2025;98:485-493.
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    August 2025
  10. CIRSTIAN R, Forde NJ, Zhang G, Hellemann GS, et al
    Lifespan Normative Models of White Matter Fractional Anisotropy: Applications to Early Psychosis.
    Biol Psychiatry. 2025 Aug 1:S0006-3223(25)01379.
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    July 2025
  11. DI BIASE MA
    Ascribing Molecular Context to Functional Brain Changes in Psychosis.
    Biol Psychiatry. 2025;98:99-101.
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  12. ZHANG T, Wei Y, Tang X, Xu L, et al
    Two-Month Cognitive Changes Enhance Prediction of Nonremission in Clinical High-Risk Individuals.
    Biol Psychiatry. 2025;98:175-185.
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  13. FORTEA A, Ortuno M, Masias M, Guasp M, et al
    Brain metabolite levels in the post-acute stage of anti-NMDA receptor encephalitis and schizophrenia: a longitudinal case-control study.
    Biol Psychiatry. 2025 Jul 12:S0006-3223(25)01316.
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  14. PENG X, Song C, Su Y, Kang D, et al
    Effects of Accelerated Intermittent Theta-Burst Stimulation Targeting the Superior Frontal Gyrus on Cognitive Function in Patients with Schizophrenia: A Double-Blind, Randomized, Sham-Controlled Clinical Trial.
    Biol Psychiatry. 2025 Jul 11:S0006-3223(25)01310.
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  15. BUCIUMAN MO, Haas SS, Antonucci LA, Sarisik E, et al
    From Snapshots to Stable Outcomes: rs-fMRI-based Prognosis of Functioning in Patients with Psychosis Risk or Recent-Onset Depression.
    Biol Psychiatry. 2025 Jul 9:S0006-3223(25)01308.
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  16. CARRION RE, John M, Dorvil S, Auther A, et al
    Exploring the pathways between early auditory processing, processing speed, social cognition, and negative symptoms on social functioning in individuals at clinical high risk for psychosis: A structural equation modeling approach.
    Biol Psychiatry. 2025 Jul 7:S0006-3223(25)01309.
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  17. MANCINI V, Delavari F, Eom TY, Zakharenko SS, et al
    How does altered function of the hippocampus contribute to the development of psychosis?
    Biol Psychiatry. 2025 Jul 5:S0006-3223(25)01296.
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  18. CAO H, Argyelan M, Yan J, Velioglu HA, et al
    Mapping cerebellar connectivity to cognition in psychosis: Convergent evidence from fMRI and TMS.
    Biol Psychiatry. 2025 Jul 3:S0006-3223(25)01297.
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    June 2025
  19. CASTELNOVO A, D'Agostino A, Mayeli A, Albantakis L, et al
    Sleep spindle abnormalities as neurophysiological biomarkers of Schizophrenia spectrum disorders: From cellular mechanisms and neural circuits to clinical implications.
    Biol Psychiatry. 2025 Jun 25:S0006-3223(25)01274.
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  20. MURRAY RM, Egerton A, Gao Y, Grace AA, et al
    Why is Clozapine uniquely Effective in Treatment Resistant Schizophrenia?
    Biol Psychiatry. 2025 Jun 23:S0006-3223(25)01270.
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  21. AWADA J, Delavari F, Bolton TAW, Alouf F, et al
    A Longitudinal and Reproducible Anti-coactivation Pattern Between the Cerebellum and the Ventral Tegmental Area Relates to Apathy in Schizophrenia.
    Biol Psychiatry. 2025 Jun 18:S0006-3223(25)01252.
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  22. SHARPE V, Mackinley M, Nour Eddine S, Wang L, et al
    Selective insensitivity to global vs. local linguistic context in speech produced by patients with untreated psychosis and positive thought disorder.
    Biol Psychiatry. 2025 Jun 10:S0006-3223(25)01243.
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    May 2025
  23. LELLA A, Antonucci LA, Passiatore R, Bellantuono L, et al
    Thalamo-cortical structural co-variation networks are related to familial risk for schizophrenia in the context of lower nuclei volume estimates in patients: an ENIGMA study.
    Biol Psychiatry. 2025 May 7:S0006-3223(25)01178.
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    April 2025
  24. VYAZOVSKIY VV, Bannerman DM
    Preclinical models for schizophrenia and sleep oscillations: from biomarkers to mechanisms.
    Biol Psychiatry. 2025 Apr 8:S0006-3223(25)01115.
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    March 2025
  25. ODKHUU S, Tang X, Kim WS, Wei Y, et al
    Brain Network Resilience and Cognitive Function in Patients with First Episode Schizophrenia Spectrum Disorders.
    Biol Psychiatry. 2025 Mar 30:S0006-3223(25)01104.
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  26. WANG D, Li D, Dang X, Mu C, et al
    Mendelian randomization reveals causalities between DNA methylation and schizophrenia.
    Biol Psychiatry. 2025 Mar 27:S0006-3223(25)01100.
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  27. ROMERO C, de Leeuw C, Schipper M, Maciel BAPC, et al
    Immune-developmental processes contribute to schizophrenia risk: insights from a genetic overlap study with height.
    Biol Psychiatry. 2025 Mar 10:S0006-3223(25)01018.
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    February 2025
  28. MOURGUES-CODERN C, Benrimoh D, Gandhi J, Farina EA, et al
    Emergence and dynamics of delusions and hallucinations across stages in early psychosis.
    Biol Psychiatry. 2025 Feb 26:S0006-3223(25)00990.
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  29. BHATTACHARYYA U, John J, Lencz T, Lam M, et al
    Dissecting Schizophrenia Biology Using Pleiotropy with Cognitive Genomics.
    Biol Psychiatry. 2025 Feb 22:S0006-3223(25)00989.
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  30. TEBARTZ VAN ELST L, Runge K, Meyer PT, Urbach H, et al
    The Neuropsychiatric Checklist for Autoimmune Psychosis: A Narrative Review.
    Biol Psychiatry. 2025 Feb 21:S0006-3223(25)00988.
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  31. AKKOUH IA, Osete JR, Szabo A, Andreassen OA, et al
    Neurobiological perturbations in bipolar disorder compared to schizophrenia - evidence from cell cultures and brain organoids.
    Biol Psychiatry. 2025 Feb 19:S0006-3223(25)00110.
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  32. KNIGHT SR, Abbasova L, Zeighami Y, Hansen JY, et al
    Transcriptional and neurochemical signatures of cerebral blood flow alterations in schizophrenia and individuals at clinical high-risk for psychosis.
    Biol Psychiatry. 2025 Feb 7:S0006-3223(25)00076.
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    January 2025
  33. FAN L, Carrico S, Zhu Y, Ackerman RA, et al
    Transcranial Direct Current Stimulation Improves Paranoia and Social Functioning in Schizophrenia: A Randomized Clinical Trial.
    Biol Psychiatry. 2025 Jan 22:S0006-3223(25)00053.
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  34. DIENEL SJ, Wade KL, Fish KN, Lewis DA, et al
    Alterations in Prefrontal Cortical Somatostatin Neurons in Schizophrenia: Evidence for Weaker Inhibition of Pyramidal Neuron Dendrites.
    Biol Psychiatry. 2025 Jan 21:S0006-3223(25)00052.
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  35. BUCK J, Horga G
    Increasing the Interpretability of Psychosis Models.
    Biol Psychiatry. 2025;97:99-101.
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  36. PEARLSON GD
    Clinical Phenotypes Associated With White Matter Microstructural Abnormalities Across Early Psychoses.
    Biol Psychiatry. 2025;97:102-103.
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    November 2024
  37. SANTONI M, Pistis M
    Maternal Immune Activation and Endocannabinoid System: Focus on Two-Hit Models of Schizophrenia.
    Biol Psychiatry. 2024 Nov 29:S0006-3223(24)01783.
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  38. ALAMIA A, Gordillo D, Chkonia E, Roinishvili M, et al
    Oscillatory traveling waves provide evidence for predictive coding abnormalities in schizophrenia.
    Biol Psychiatry. 2024 Nov 28:S0006-3223(24)01782.
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  39. LIZANO P, Velez-Perez E
    Multimodal Retinal Imaging Findings in Schizophrenia Spectrum Disorders.
    Biol Psychiatry. 2024;96:769-771.
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  40. HE Y, Zhao L, Chen X
    Tracing the Trajectory: Polyunsaturated Fatty Acids and Early Adult Psychosis.
    Biol Psychiatry. 2024;96:768.
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    October 2024
  41. CHENGAPPA KNR, Shekhar A
    Novel Ideas for Drug Discovery in the Treatment of People With Schizophrenia.
    Biol Psychiatry. 2024;96:624-626.
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    September 2024
  42. STAGLIN B
    The Future of Schizophrenia Care: A Lived Experience-Based Call for Innovation.
    Biol Psychiatry. 2024 Sep 23:S0006-3223(24)01613.
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  43. HECKERS S, Feola B
    Perceived Stress and Hippocampal Volume in Psychosis.
    Biol Psychiatry. 2024;96:329-330.
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  44. YOHN SE, Breier A, Paul SM
    Altered Vesicular Acetylcholine Transporter Availability in Schizophrenia: Association With Positive Symptoms and Cognitive Impairment.
    Biol Psychiatry. 2024;96:324-325.
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    August 2024
  45. MIKUS N, Lamm C, Mathys C
    Computational phenotyping of aberrant belief updating in individuals with schizotypal traits and schizophrenia.
    Biol Psychiatry. 2024 Aug 30:S0006-3223(24)01554.
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  46. SEHATPOUR P, Kantrowitz JT
    Finding the right dose: NMDAR modulating treatments for cognitive and plasticity deficits in schizophrenia and the role of pharmacodynamic target engagement.
    Biol Psychiatry. 2024 Aug 30:S0006-3223(24)01552.
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  47. SCHLEIFER CH, Chang SE, Amir CM, O'Hora KP, et al
    Unique functional neuroimaging signatures of genetic versus clinical high risk for psychosis.
    Biol Psychiatry. 2024 Aug 22:S0006-3223(24)01538.
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  48. LIDDLE PF, Sami MB
    The mechanisms of persisting disability in schizophrenia: imprecise predictive coding via cortico-striatal-thalamo-cortical loop dysfunction.
    Biol Psychiatry. 2024 Aug 22:S0006-3223(24)01535.
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  49. CHENG Y, Cai H, Liu S, Yang Y, et al
    Brain network localization of gray matter atrophy, neurocognitive and social cognitive dysfunction in schizophrenia.
    Biol Psychiatry. 2024 Aug 3:S0006-3223(24)01489.
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  50. GAO Z, Lui S
    Combining Radiomics With Connectomics: A Promising New Approach to Characterize Dysconnectivity in Schizophrenia.
    Biol Psychiatry. 2024;96:162-163.
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  51. JEFSEN OH, Holde K, McGrath JJ, Rajagopal VM, et al
    Polygenic Risk of Mental Disorders and Subject-Specific School Grades.
    Biol Psychiatry. 2024;96:222-229.
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    July 2024
  52. CHOPRA S, Levi PT, Holmes A, Orchard ER, et al
    Brain-wide Anatomical Connectivity and Prediction of Longitudinal Outcomes in Antipsychotic-Naive First Episode Psychosis.
    Biol Psychiatry. 2024 Jul 26:S0006-3223(24)01483.
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  53. WARD HB, Beermann A, Xie J, Yildiz G, et al
    Robust Brain Correlates of Cognitive Performance in Psychosis and its Prodrome.
    Biol Psychiatry. 2024 Jul 18:S0006-3223(24)01460.
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  54. FULFORD D, Marsch LA, Pratap A
    Prescription digital therapeutics: An emerging treatment option for negative symptoms in schizophrenia.
    Biol Psychiatry. 2024 Jul 1:S0006-3223(24)01430.
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    June 2024
  55. GANAPATHIRAJU MK, Triptish B, Deshpande S, Wesesky M, et al
    Schizophrenia interactome derived repurposable drugs and randomized control trials of two candidates.
    Biol Psychiatry. 2024 Jun 29:S0006-3223(24)01426.
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  56. VANO LJ, McCutcheon RA, Rutigliano G, Kaar SJ, et al
    Mesostriatal Dopaminergic Circuit Dysfunction in Schizophrenia: A Multimodal Neuromelanin-sensitive MRI and [18F]-DOPA PET Study.
    Biol Psychiatry. 2024 Jun 26:S0006-3223(24)01417.
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  57. CHANG K, Jian X, Wu C, Gao C, et al
    The Contribution of Mosaic Chromosomal Alterations to Schizophrenia.
    Biol Psychiatry. 2024 Jun 26:S0006-3223(24)01419.
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  58. WANG HR, Liu ZQ, Nakua H, Hegarty CE, et al
    Decoding Early Psychoses: Unraveling Stable Microstructural Features Associated with Psychopathology Across Independent Cohorts.
    Biol Psychiatry. 2024 Jun 20:S0006-3223(24)01391.
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  59. JIAO X, Hu Q, Tang Y, Zhang T, et al
    Abnormal Global Cortical Responses in Drug-naive Patients with Schizophrenia following Orbitofrontal Cortex Stimulation: A Concurrent TMS-EEG Study.
    Biol Psychiatry. 2024 Jun 7:S0006-3223(24)01364.
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  60. KRAKOWSKI K, Oliver D, Arribas M, Stahl D, et al
    Dynamic and transdiagnostic risk calculator based on Natural Language Processing for the prediction of psychosis in secondary mental health care: development and internal-external validation cohort study.
    Biol Psychiatry. 2024 Jun 7:S0006-3223(24)01361.
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  61. KOCHUNOV PV, Hong LE
    Is Schizophrenia a Disorder of Accelerated Whole-System Aging?
    Biol Psychiatry. 2024;95:988-989.
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    May 2024
  62. HOWES OD, Dawkins E, Lobo MC, Kaar SJ, et al
    New drug treatments for schizophrenia: a review of approaches to target circuit dysfunction.
    Biol Psychiatry. 2024 May 28:S0006-3223(24)01349.
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  63. LU T, Chen Y, Yoshiji S, Ilboudo Y, et al
    Circulating metabolite abundances associated with risks of bipolar disorder, schizophrenia, and depression: a Mendelian randomization study.
    Biol Psychiatry. 2024 May 3:S0006-3223(24)01285.
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    April 2024
  64. BOUDRIOT E, Gabriel V, Popovic D, Pingen P, et al
    Signature of altered retinal microstructures and electrophysiology in schizophrenia spectrum disorders is associated with disease severity and polygenic risk.
    Biol Psychiatry. 2024 Apr 26:S0006-3223(24)01262.
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  65. MONGAN D, Perry BI, Healy C, Susai SR, et al
    Longitudinal trajectories of plasma polyunsaturated fatty acids and associations with psychosis-spectrum outcomes in early adulthood.
    Biol Psychiatry. 2024 Apr 15:S0006-3223(24)01229.
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  66. KIM J, Park IH
    Identifying an Early Neuropathological Mechanism in Schizophrenia With Brain Organoids.
    Biol Psychiatry. 2024;95:608-610.
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  67. RADHAKRISHNAN R
    In Vivo Synaptic Density in Early Schizophrenia: Are There No Differences or Are They Too Small to Detect?
    Biol Psychiatry. 2024;95:605-607.
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  68. STEIN F, Gruber M, Mauritz M, Brosch K, et al
    Brain Structural Network Connectivity of Formal Thought Disorder Dimensions in Affective and Psychotic Disorders.
    Biol Psychiatry. 2024;95:629-638.
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    March 2024
  69. PAUL SM, Yohn SE, Brannan SK, Neugebauer NM, et al
    Muscarinic Receptor Activators as Novel Treatments for Schizophrenia.
    Biol Psychiatry. 2024 Mar 25:S0006-3223(24)01173.
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  70. GONZALEZ-PENAS J, Alloza C, Brouwer R, Diaz-Caneja CM, et al
    Accelerated Cortical Thinning in Schizophrenia is Associated With Rare and Common Predisposing Variation to Schizophrenia and Neurodevelopmental Disorders.
    Biol Psychiatry. 2024 Mar 21:S0006-3223(24)01170.
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    February 2024
  71. MEHTA UM, Ithal D, Roy N, Shekhar S, et al
    Posterior Cerebellar Resting-State Functional Hypoconnectivity: A Neural Marker of Schizophrenia across Different Stages of Treatment Response.
    Biol Psychiatry. 2024 Feb 7:S0006-3223(24)00076.
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  72. WEINSTEIN JJ, Moeller SJ, Perlman G, Gil R, et al
    Imaging the Vesicular Acetylcholine Transporter in Schizophrenia: a PET study using [(18)F]-VAT.
    Biol Psychiatry. 2024 Feb 1:S0006-3223(24)00062.
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    January 2024
  73. MAXIMO JO, Armstrong WP, Kraguljac NV, Lahti AC, et al
    Higher-Order Intrinsic Brain Network Trajectories after Antipsychotic Treatment in Medication-Naive First Episode Psychosis Patients.
    Biol Psychiatry. 2024 Jan 23:S0006-3223(24)00037.
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  74. PRELLER KH, Scholpp J, Wunder A, Rosenbrock H, et al
    Neuroimaging biomarkers for drug discovery and development in Schizophrenia.
    Biol Psychiatry. 2024 Jan 23:S0006-3223(24)00036.
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  75. MARIANO M, Rossetti I, Maravita A, Paulesu E, et al
    Sensory attenuation deficit and auditory hallucinations in schizophrenia: a causal mechanism or a risk factor? Evidence from meta-analyses on N1 ERP-EEG component.
    Biol Psychiatry. 2024 Jan 19:S0006-3223(24)00035.
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  76. MA Y, Bendl J, Hartley BJ, Fullard JF, et al
    Activity-Dependent Transcriptional Program in NGN2+ Neurons Enriched for Genetic Risk for Brain-Related Disorders.
    Biol Psychiatry. 2024;95:187-198.
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  77. DING H, Zhang Y, Xie Y, Du X, et al
    Individualized texture similarity network in schizophrenia.
    Biol Psychiatry. 2024 Jan 11:S0006-3223(24)00029.
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    December 2023
  78. CLIFTON NE, Lin JQ, Holt CE, O'Donovan MC, et al
    Enrichment of the local synaptic translatome for genetic risk associated with schizophrenia and autism spectrum disorder.
    Biol Psychiatry. 2023 Dec 14:S0006-3223(23)01764.
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  79. ABERIZK K, Addington JM, Bearden CE, Cadenhead KS, et al
    Relations of Lifetime Perceived Stress and Basal Cortisol with Hippocampal Volume among Healthy Adolescents and those at Clinical High-Risk for Psychosis: A Structural Equation Modeling Approach.
    Biol Psychiatry. 2023 Dec 11:S0006-3223(23)01759.
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  80. IRAJI A, Chen J, Lewis N, Faghiri A, et al
    Spatial Dynamic Subspaces Encode Sex-Specific Schizophrenia Disruptions in Transient Network Overlap and its Links to Genetic Risk.
    Biol Psychiatry. 2023 Dec 7:S0006-3223(23)01756.
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  81. DOGRA S, Aguayo C, Xiang Z, Putnam J, et al
    Activation of metabotropic glutamate receptor 3 modulates thalamo-accumbal transmission and rescues schizophrenia-like physiological and behavioral deficits.
    Biol Psychiatry. 2023 Dec 5:S0006-3223(23)01753.
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  82. SEN P, Prandovszky E, Honkanen JK, Chen O, et al
    Dysregulation of microbiota in first episode psychosis patients were associated with symptom severity and treatment response.
    Biol Psychiatry. 2023 Dec 5:S0006-3223(23)01751.
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    November 2023
  83. ST GEORGE-HYSLOP F, Haneklaus M, Kivisild T, Livesey FJ, et al
    Loss of CNTNAP2 Alters Human Cortical Excitatory Neuron Differentiation and Neural Network Development.
    Biol Psychiatry. 2023;94:780-791.
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  84. CANNON TD
    On the clinical utility of individualized prediction models for psychosis in at risk youth.
    Biol Psychiatry. 2023 Nov 8:S0006-3223(23)01696.
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  85. CASPI A, Shireby G, Mill J, Moffitt TE, et al
    Accelerated pace of aging in schizophrenia: Five case-control studies.
    Biol Psychiatry. 2023 Nov 2:S0006-3223(23)01693.
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  86. HARVANEK ZM, Boks MP, Vinkers CH, Higgins-Chen AT, et al
    The Cutting Edge of Epigenetic Clocks: In Search of Mechanisms Linking Aging and Mental Health.
    Biol Psychiatry. 2023;94:694-705.
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    October 2023
  87. ROGDAKI M
    From Gene to Brain and Behavior: Excitatory and Inhibitory Imbalance and Psychosis in Individuals With 22q11.2 Deletion Syndrome.
    Biol Psychiatry. 2023;94:526-527.
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    September 2023
  88. AKKOUH IA, Ueland T, Szabo A, Hughes T, et al
    Longitudinal transcriptomic analysis of human cortical spheroids identifies axonal dysregulation in the prenatal brain as a mediator of genetic risk for schizophrenia.
    Biol Psychiatry. 2023 Sep 1:S0006-3223(23)01529.
    >> Share


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