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Articles published in
Am J Psychiatry
    March 2026
  1. MARDER SR
    Finding a Medication for Negative Symptoms in Schizophrenia: Why So Many Failures?
    Am J Psychiatry. 2026;183:154-155.
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  2. MYUNG W, Ahn Y, Kim J, Won HH, et al
    Targeted Therapeutic Intervention for Problematic Alcohol Use, Comorbid Depressive Disorder, and Schizophrenia: Response to Lawford and Norrie.
    Am J Psychiatry. 2026;183:216.
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  3. LI C, Sun P
    Overlooked Methodological Limitations in the Study of Grip Strength and Default Mode Network Connectivity in Early Psychosis.
    Am J Psychiatry. 2026;183:214.
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  4. KALIN NH
    Advances Relevant to Treating Bipolar Disorder, PTSD, and Schizophrenia.
    Am J Psychiatry. 2026;183:149-151.
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    February 2026
  5. KAUL I, Claxton A, Sauder C, Patel T, et al
    Long-Term Safety and Efficacy of Xanomeline and Trospium Chloride in Schizophrenia: A 52-Week Open-Label Extension Trial.
    Am J Psychiatry. 2026 Feb 4:appiajp20241186. doi: 10.1176/appi.ajp.20241186.
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  6. KALIN NH
    Neuroplasticity, Antipsychotic Efficacy, Schizophrenia Risk Reduction With Doxycycline Exposure, and Cannabis and Alcohol Use Interactions.
    Am J Psychiatry. 2026;183:87-89.
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    December 2025
  7. KELLNER CH
    Electroconvulsive Therapy (ECT) for Postpartum Psychosis: Treatment for a Medical Emergency.
    Am J Psychiatry. 2025;182:1093.
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  8. BERGINK V, Kamperman A, Robakis T
    Electroconvulsive Therapy (ECT) for Postpartum Psychosis: Treatment for a Medical Emergency: Response to Kellner.
    Am J Psychiatry. 2025;182:1094.
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    November 2025
  9. KANTROWITZ JT, Mayer MR, Choo TH, Liu K, et al
    Effect Size Deflation With Increasing Sample Size in Adjunctive Trials for Negative Symptoms in Schizophrenia: A Meta-Analysis and Meta-Regression Across Mechanisms of Action.
    Am J Psychiatry. 2025 Nov 19:appiajp20250034. doi: 10.1176/appi.ajp.20250034.
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  10. LANG U, Metsala J, Ramsay H, Boland F, et al
    Doxycycline Use in Adolescent Psychiatric Patients and Risk of Schizophrenia: An Emulated Target Trial.
    Am J Psychiatry. 2025 Nov 5:appiajp20240958. doi: 10.1176/appi.ajp.20240958.
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  11. KALIN NH
    Schizophrenia, Alcohol Use Disorder, and Stimulant Use Disorder.
    Am J Psychiatry. 2025;182:957-959.
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  12. YALCINBAS EA, Ajanaku B, Nelson ED, Garcia-Flores R, et al
    Transcriptomic Analysis of the Human Habenula in Schizophrenia.
    Am J Psychiatry. 2025;182:991-1006.
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  13. GUR RE
    Pathways to Psychosis: Factors Associated With Risk for Psychosis Spectrum Disorders.
    Am J Psychiatry. 2025;182:984-990.
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    October 2025
  14. ZHAO G, Sun Y, Zhang Y, Lu T, et al
    Efficacy and Tolerability of Seven Antipsychotic Drugs in Acutely Ill Patients With Schizophrenia: A Randomized, Multicenter, Assessor-Blinded Trial.
    Am J Psychiatry. 2025 Oct 29:appiajp20250111. doi: 10.1176/appi.ajp.20250111.
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  15. HOWES OD, Bukala BR, Chen EYH, Correll CU, et al
    Relapse in Schizophrenia: A Systematic Review of Criteria for Clinical Studies and International Consensus Guidelines to Improve Them.
    Am J Psychiatry. 2025 Oct 8:appiajp20241040. doi: 10.1176/appi.ajp.20241040.
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    September 2025
  16. KALIN NH
    Scientific Advances Relevant to Schizophrenia, Psychosis, and the Treatment of Methamphetamine Use Disorder.
    Am J Psychiatry. 2025;182:797-800.
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  17. HORAN WP, Harvey PD, Brannan SK
    Does Xanomeline/Trospium Have Unique Benefits for Cognitive Impairment Associated With Schizophrenia? Response to Tandon.
    Am J Psychiatry. 2025;182:878-879.
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  18. CASSIDY C, Wang Y, Abi-Dargham A
    Forging a Role for Iron in the Dopamine Dysfunction of Schizophrenia.
    Am J Psychiatry. 2025;182:804-806.
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  19. VANO LJ, McCutcheon RA, Sedlacik J, Kaar SJ, et al
    Reduced Brain Iron and Striatal Hyperdopaminergia in Schizophrenia: A Quantitative Susceptibility Mapping MRI and PET Study.
    Am J Psychiatry. 2025;182:830-839.
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  20. TANDON R
    Does Xanomeline/Trospium Have Unique Benefits for Cognitive Impairment Associated With Schizophrenia?
    Am J Psychiatry. 2025;182:878.
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  21. ANGLIN DM, Olfson M, van der Ven E, Oh H, et al
    Neighborhood Social Vulnerability and Racial Disparities in Schizophrenia Spectrum Disorder Prevalence.
    Am J Psychiatry. 2025;182:850-860.
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    July 2025
  22. AHN Y, Kim J, Jung K, Lee DJ, et al
    Relationship Between Problematic Alcohol Use and Various Psychiatric Disorders: A Genetically Informed Study.
    Am J Psychiatry. 2025;182:671-682.
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    June 2025
  23. WARD HB, Beermann A, Manzanarez Felix K, Narisetti L, et al
    Grip Strength as a Marker of Resting-State Network Integrity and Well-Being in Early Psychosis.
    Am J Psychiatry. 2025 Jun 25:appiajp20240780. doi: 10.1176/appi.ajp.20240780.
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  24. KALIN NH
    Depression, Inflammation, and Postpartum Psychosis.
    Am J Psychiatry. 2025;182:501-503.
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  25. DAZZAN P
    A Step Closer to Understanding Familial Risk for Postpartum Psychosis.
    Am J Psychiatry. 2025;182:504-505.
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    May 2025
  26. ZHANG L, Ivleva EI, Parker DA, Hill SK, et al
    Impact of Polygenic Interactions With Anticholinergic Burden on Cognition and Brain Structure in Psychosis Spectrum Disorders.
    Am J Psychiatry. 2025 May 28:appiajp20240709. doi: 10.1176/appi.ajp.20240709.
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  27. KEPINSKA AP, Robakis TK, Humphreys K, Liu X, et al
    Familial Risk of Postpartum Psychosis.
    Am J Psychiatry. 2025 May 19:appiajp20230576. doi: 10.1176/appi.ajp.20230576.
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    April 2025
  28. CHENGAPPA KNR, Gannon JM, Joshi YB
    A Call to Psychiatrists: Deprescription of Unnecessary Anticholinergic Medications in Schizophrenia Must Start Now.
    Am J Psychiatry. 2025;182:319-321.
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  29. PERLIS RH
    Targeting Schizophrenia.
    Am J Psychiatry. 2025;182:329-331.
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  30. ORHAN F, Malwade S, Khanlarkhani N, Gkogka A, et al
    Kynurenic Acid and Promotion of Activity-Dependent Synapse Elimination in Schizophrenia.
    Am J Psychiatry. 2025;182:389-400.
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  31. ZHOU L, Sommer IEC, Yang P, Sikirin L, et al
    What Do Four Decades of Research Tell Us About the Association Between Childhood Adversity and Psychosis: An Updated and Extended Multi-Level Meta-Analysis.
    Am J Psychiatry. 2025;182:360-372.
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  32. KALIN NH
    Psychotic Disorders and Schizophrenia: Treatment, Risk, Brain Alterations, and Mechanisms.
    Am J Psychiatry. 2025;182:313-315.
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  33. NEUFELD NH, Blumberger DM
    An Update on the Use of Neuromodulation Strategies in the Treatment of Schizophrenia.
    Am J Psychiatry. 2025;182:332-340.
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    March 2025
  34. CORLETT PR, Fraser KM
    20 Years of Aberrant Salience in Psychosis: What Have We Learned?
    Am J Psychiatry. 2025 Mar 26:appiajp20240556. doi: 10.1176/appi.ajp.20240556.
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  35. KALIN NH
    New Developments in the Treatment of Depression, OCD, and Schizophrenia.
    Am J Psychiatry. 2025;182:223-226.
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  36. JAVITT DC
    Xanomeline-Trospium Treatment of Cognitive Impairments of Schizophrenia: Hope for Some, or Hope for All?
    Am J Psychiatry. 2025;182:237-239.
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    February 2025
  37. OMLOR W, Rabe F, Fuchs S, Surbeck W, et al
    Estimating Multimodal Structural Brain Variability in Schizophrenia Spectrum Disorders: A Worldwide ENIGMA Study.
    Am J Psychiatry. 2025 Feb 26:appiajp20230806. doi: 10.1176/appi.ajp.20230806.
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  38. MANCINI V, Latreche C, Fanshawe JB, Varvari I, et al
    Anticholinergic Burden and Cognitive Function in Psychosis: A Systematic Review and Meta-Analysis.
    Am J Psychiatry. 2025 Feb 26:appiajp20240260. doi: 10.1176/appi.ajp.20240260.
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  39. TIIHONEN J, Tanskanen A, Solmi M, Rubio JM, et al
    Continuous Dopamine D(2) Receptor Blockade and Long-Term Outcome in First-Episode Schizophrenia.
    Am J Psychiatry. 2025 Feb 19:0. doi: 10.1176/appi.ajp.20240321.
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    December 2024
  40. HORAN WP, Sauder C, Harvey PD, Ramsay IS, et al
    The Impact of Xanomeline and Trospium Chloride on Cognitive Impairment in Acute Schizophrenia: Replication in Pooled Data From Two Phase 3 Trials.
    Am J Psychiatry. 2024 Dec 11. doi: 10.1176/appi.ajp.20240076.
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    October 2024
  41. GALLUCCI J, Yu JC, Oliver LD, Nakua H, et al
    Neural Circuitry and Therapeutic Targeting of Depressive Symptoms in Schizophrenia Spectrum Disorders.
    Am J Psychiatry. 2024;181:910-919.
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  42. REILLY TJ, McCutcheon RA
    Menopausal Hormone Therapy for Women With Schizophrenia: What's Stopping Us?
    Am J Psychiatry. 2024;181:854-855.
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  43. KRAMER EN, Velicu V
    Aripiprazole Augmentation as a Treatment for Clozapine-Induced Weight Gain.
    Am J Psychiatry. 2024;181:935-936.
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  44. CHENGAPPA KNR, Cotes RO
    Clozapine's High Incidence of Ileus and Pneumonia Demand Better Clinical Strategies-How Do We Get There?
    Am J Psychiatry. 2024;181:851-853.
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  45. MCINTYRE RS, Kwan ATH, Rosenblat JD, Teopiz KM, et al
    Aripiprazole Augmentation as a Treatment for Clozapine-Induced Weight Gain: Response to Kramer and Velicu.
    Am J Psychiatry. 2024;181:936-937.
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  46. HWANG M, Brady R
    Neural Circuitry and Therapeutic Targeting of Depressive Symptoms in Schizophrenia Spectrum Disorders.
    Am J Psychiatry. 2024;181:858-860.
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  47. ARNSTEN AFT, Datta D
    Characterizing the Most Vulnerable Prefrontal Cortical Neurons in Schizophrenia.
    Am J Psychiatry. 2024;181:861-864.
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  48. TAMMINGA CA
    Psychosis Risk With Prescription Amphetamine.
    Am J Psychiatry. 2024;181:856-857.
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  49. KALIN NH
    Schizophrenia Spectrum Disorders and Psychosis.
    Am J Psychiatry. 2024;181:847-850.
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  50. LEUCHT S, Priller J, Davis JM
    Antipsychotic Drugs: A Concise Review of History, Classification, Indications, Mechanism, Efficacy, Side Effects, Dosing, and Clinical Application.
    Am J Psychiatry. 2024;181:865-878.
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  51. ARION D, Enwright JF 3rd, Gonzalez-Burgos G, Lewis DA, et al
    Cell Type-Specific Profiles and Developmental Trajectories of Transcriptomes in Primate Prefrontal Layer 3 Pyramidal Neurons: Implications for Schizophrenia.
    Am J Psychiatry. 2024;181:920-934.
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    September 2024
  52. PARTANEN JJ, Happola P, Kampe A, Ahola-Olli A, et al
    High Burden of Ileus and Pneumonia in Clozapine-Treated Individuals With Schizophrenia: A Finnish 25-Year Follow-Up Register Study.
    Am J Psychiatry. 2024 Sep 12:appiajp20230744. doi: 10.1176/appi.ajp.20230744.
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  53. MORAN LV, Skinner JP, Shinn AK, Nielsen K, et al
    Risk of Incident Psychosis and Mania With Prescription Amphetamines.
    Am J Psychiatry. 2024 Sep 12:appiajp20230329. doi: 10.1176/appi.ajp.20230329.
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  54. BRAND BA, Sommer IE, Gangadin SS, Tanskanen A, et al
    Real-World Effectiveness of Menopausal Hormone Therapy in Preventing Relapse in Women With Schizophrenia or Schizoaffective Disorder.
    Am J Psychiatry. 2024 Sep 12:appiajp20230850. doi: 10.1176/appi.ajp.20230850.
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    July 2024
  55. JONSSON L, Horbeck E, Primerano A, Song J, et al
    Association of Occupational Dysfunction and Hospital Admissions With Different Polygenic Profiles in Bipolar Disorder.
    Am J Psychiatry. 2024;181:620-629.
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    June 2024
  56. KURTZ MM
    Cognitive Remediation in Schizophrenia Spectrum Illness: Evidence for Treatment Persistence.
    Am J Psychiatry. 2024;181:471-473.
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  57. VANO LJ, Veronese M, McCutcheon RA, Howes OD, et al
    Neuromelanin-Sensitive MRI: A Biomarker for Treatment-Resistant Schizophrenia?
    Am J Psychiatry. 2024;181:468-470.
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  58. BRENNAND KJ
    Aligning Stem Cell Models and Postmortem Studies to Query Striatal Neurodevelopment in Schizophrenia.
    Am J Psychiatry. 2024;181:465-467.
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  59. BIRNBAUM R, Weinberger DR
    The Genesis of Schizophrenia: An Origin Story.
    Am J Psychiatry. 2024;181:482-492.
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  60. KALIN NH
    Advances in Understanding Schizophrenia, ADHD, and ASD.
    Am J Psychiatry. 2024;181:461-464.
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  61. TRAMAZZO S, Lian W, Ajnakina O, Carlson G, et al
    Long-Term Course of Remission and Recovery in Psychotic Disorders.
    Am J Psychiatry. 2024;181:532-540.
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    May 2024
  62. KANG J, Castro VM, Ripperger M, Venkatesh S, et al
    Genome-Wide Association Study of Treatment-Resistant Depression: Shared Biology With Metabolic Traits.
    Am J Psychiatry. 2024 May 15:appiajp20230247. doi: 10.1176/appi.ajp.20230247.
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    April 2024
  63. LIGHT GA, Swerdlow NR
    Predicting Conversion to Psychosis: What Lies Beyond the Biomarkers?
    Am J Psychiatry. 2024;181:272-274.
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    March 2024
  64. VAN DER PLUIJM M, Wengler K, Reijers PN, Cassidy CM, et al
    Neuromelanin-Sensitive MRI as Candidate Marker for Treatment Resistance in First-Episode Schizophrenia.
    Am J Psychiatry. 2024 Mar 13:appiajp20220780. doi: 10.1176/appi.ajp.20220780.
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  65. VITA A, Barlati S, Ceraso A, Nibbio G, et al
    Durability of Effects of Cognitive Remediation on Cognition and Psychosocial Functioning in Schizophrenia: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
    Am J Psychiatry. 2024 Mar 13:appiajp20230396. doi: 10.1176/appi.ajp.20230396.
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    February 2024
  66. HOU Y, Xia H, He T, Zhang B, et al
    N2 Responses in Youths With Psychosis Risk Syndrome and Their Association With Clinical Outcomes: A Cohort Follow-Up Study Based on the Three-Stimulus Visual Oddball Paradigm.
    Am J Psychiatry. 2024 Feb 29:appiajp20221013. doi: 10.1176/appi.ajp.20221013.
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  67. ROGNLI EB, Hoye A, Bramness JG
    Methamphetamine-Induced Psychosis and Schizophrenia: A Call for Special Attention: Response to Zhu et al.
    Am J Psychiatry. 2024;181:168-169.
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  68. ZHU L, Ni T, Guan F
    Methamphetamine-Induced Psychosis and Schizophrenia: A Call for Special Attention.
    Am J Psychiatry. 2024;181:168.
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    November 2023
  69. SAWADA T, Barbosa AR, Araujo B, McCord AE, et al
    Recapitulation of Perturbed Striatal Gene Expression Dynamics of Donor's Brains With Ventral Forebrain Organoids Derived From the Same Individuals With Schizophrenia.
    Am J Psychiatry. 2023 Nov 2:appiajp20220723. doi: 10.1176/appi.ajp.20220723.
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  70. KALIN NH
    New Insights Into Psychotic Disorders.
    Am J Psychiatry. 2023;180:779-781.
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  71. VAN DER VEN E, Susser E
    Structural Racism and Risk of Schizophrenia.
    Am J Psychiatry. 2023;180:782-784.
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  72. CANNON TD
    Predicting Conversion to Psychosis Using Machine Learning: Are We There Yet?
    Am J Psychiatry. 2023;180:789-791.
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  73. GOFF DC, Roffman J, Holt DJ
    Another Step Toward the Prediction of Antipsychotic Treatment Response Using Functional Connectivity.
    Am J Psychiatry. 2023;180:787-788.
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  74. FORSYTH JK, Bearden CE
    Rethinking the First Episode of Schizophrenia: Identifying Convergent Mechanisms During Development and Moving Toward Prediction.
    Am J Psychiatry. 2023;180:792-804.
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  75. STRAWBRIDGE RJ, Graham N
    Dissecting the Genetic Relationship Between Schizophrenia and Cardiovascular Disease.
    Am J Psychiatry. 2023;180:785-786.
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  76. JOSHI Y, Swerdlow N, Light G
    Points that Need Attention in Early Auditory Information Processing Research in Schizophrenia: Response to Lin and Hsieh.
    Am J Psychiatry. 2023;180:841-842.
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    October 2023
  77. SMUCNY J, Davidson I, Carter CS
    Are We There Yet? Predicting Conversion to Psychosis Using Machine Learning.
    Am J Psychiatry. 2023 Oct 4:appiajp20220973. doi: 10.1176/appi.ajp.20220973.
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    September 2023
  78. RODEVAND L, Rahman Z, Hindley GFL, Smeland OB, et al
    Characterizing the Shared Genetic Underpinnings of Schizophrenia and Cardiovascular Disease Risk Factors.
    Am J Psychiatry. 2023 Sep 27:appiajp20220660. doi: 10.1176/appi.ajp.20220660.
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  79. KUMAR K, Modenato C, Moreau C, Ching CRK, et al
    Subcortical Brain Alterations in Carriers of Genomic Copy Number Variants.
    Am J Psychiatry. 2023;180:685-698.
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