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Articles published in
Clin Cancer Res
    November 2024
  1. HAFFNER MC, Morris MJ, Ding CC, Sayar E, et al
    Framework for the Pathology Workup of Metastatic Castration-Resistant Prostate Cancer Biopsies.
    Clin Cancer Res. 2024 Nov 26. doi: 10.1158/1078-0432.CCR-24-2061.
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  2. WINQUIST E, Hotte SJ, Chi K, Sridhar S, et al
    Randomized Phase II Study of Durvalumab with or without Tremelimumab in Patients with Metastatic Castration Resistant Prostate Cancer.
    Clin Cancer Res. 2024 Nov 8. doi: 10.1158/1078-0432.CCR-24-1612.
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  3. NAWFAL R, El Hajj Chehade R, Berchuck JE
    Unearthing a prostate cancer cfDNA signature that "stems" from AR alterations.
    Clin Cancer Res. 2024 Nov 4. doi: 10.1158/1078-0432.CCR-24-2849.
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    October 2024
  4. STOPSACK KH, Vijai J, Conry M, Berchuck JE, et al
    Germline DNA damage repair variants and prognosis of patients with high-risk or metastatic prostate cancer.
    Clin Cancer Res. 2024 Oct 25. doi: 10.1158/1078-0432.CCR-24-2483.
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    September 2024
  5. ISAACSSON VELHO P, Bastos DA, Saint'ana PT, Rigatti B, et al
    Nivolumab in patients with metastatic castration-resistant prostate cancer with and without DNA repair defects.
    Clin Cancer Res. 2024 Sep 27. doi: 10.1158/1078-0432.CCR-24-1595.
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  6. CHOU J, Robinson TM, Egusa EA, Lodha R, et al
    Synthetic Lethal Targeting of Cyclin Dependent Kinase-12-Deficient Prostate Cancer with PARP Inhibitors.
    Clin Cancer Res. 2024 Sep 25. doi: 10.1158/1078-0432.CCR-23-3785.
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  7. JENSEN JL, Bobek O, Chan ICC, Miller BC, et al
    Clonal Hematopoiesis and Clinical Outcomes in Metastatic Castration-Resistant Prostate Cancer Patients Given Androgen Receptor Pathway Inhibitors (Alliance A031201).
    Clin Cancer Res. 2024 Sep 17:OF1-OF10. doi: 10.1158/1078-0432.CCR-24-0803.
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  8. DALLOS MC, Obradovic AZ, McCann P, Chowdhury N, et al
    Androgen Deprivation Therapy Drives a Distinct Immune Phenotype in Localized Prostate Cancer.
    Clin Cancer Res. 2024 Sep 13. doi: 10.1158/1078-0432.CCR-24-0060.
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    August 2024
  9. CHAUHAN PS, Alahi I, Sinha S, Ledet EM, et al
    Genomic and epigenomic analysis of plasma cell-free DNA identifies stemness features associated with worse survival in lethal prostate cancer.
    Clin Cancer Res. 2024 Aug 23. doi: 10.1158/1078-0432.CCR-24-1658.
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  10. HUSSAIN M, Kocherginsky M, Agarwal N, Adra N, et al
    Abiraterone, Olaparib, or Abiraterone + Olaparib in First-line Metastatic Castration-Resistant Prostate Cancer with DNA Repair Defects (BRCAAway).
    Clin Cancer Res. 2024 Aug 8. doi: 10.1158/1078-0432.CCR-24-1402.
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  11. NGUYEN CB, Reimers MA, Perera C, Abida W, et al
    Evaluating Immune Checkpoint Blockade in Metastatic Castration-Resistant Prostate Cancers with Deleterious CDK12 Alterations in the Phase 2 IMPACT Trial.
    Clin Cancer Res. 2024;30:3200-3210.
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    July 2024
  12. SWEENEY CJ, Petry R, Xu C, Childress M, et al
    Circulating Tumor DNA Assessment for Treatment Monitoring Adds Value to PSA in Metastatic Castration Resistant Prostate Cancer.
    Clin Cancer Res. 2024 Jul 11. doi: 10.1158/1078-0432.CCR-24-1096.
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  13. LENIS AT, Ravichandran V, Brown S, Alam SM, et al
    Microsatellite Instability, Tumor Mutational Burden, and Response to Immune Checkpoint Blockade in Patients with Prostate Cancer.
    Clin Cancer Res. 2024 Jul 1. doi: 10.1158/1078-0432.CCR-23-3403.
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    April 2024
  14. APARICIO AM, Tidwell RSS, Yadav SS, Chen JS, et al
    A Modular Trial of Androgen Signaling Inhibitor Combinations Testing a Risk-Adapted Strategy in Patients with Metastatic Castration-Resistant Prostate Cancer.
    Clin Cancer Res. 2024 Apr 29. doi: 10.1158/1078-0432.CCR-23-3740.
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  15. ARCHER S, Brailey PM, Song M, Bartlett PD, et al
    CB307: A Dual Targeting Costimulatory Humabody VH Therapeutic for Treating PSMA-Positive Tumors.
    Clin Cancer Res. 2024;30:1595-1606.
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  16. SCHATZ CA, Zitzmann-Kolbe S, Moen I, Klotz M, et al
    Preclinical efficacy of a PSMA-targeted actinium-225 conjugate (225Ac-macropa-pelgifatamab) - a targeted alpha therapy for prostate cancer.
    Clin Cancer Res. 2024 Apr 9. doi: 10.1158/1078-0432.CCR-23-3746.
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  17. CHO H, Byun SS, Son NH, Chung JI, et al
    Impact of Circulating Tumor Cell-Expressed Prostate-Specific Membrane Antigen and Prostate-Specific Antigen Transcripts in Different Stages of Prostate Cancer.
    Clin Cancer Res. 2024 Apr 8:OF1-OF13. doi: 10.1158/1078-0432.CCR-23-3083.
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    March 2024
  18. DESAI KB, Serritella AV, Stadler WM, O'Donnell PH, et al
    A phase I trial of enzalutamide plus selective glucocorticoid receptor modulator relacorilant in patients with metastatic castration resistant prostate cancer.
    Clin Cancer Res. 2024 Mar 27. doi: 10.1158/1078-0432.CCR-23-3636.
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  19. AGARWAL N, Castellano D, Alonso-Gordoa T, Arranz Arija JA, et al
    A Signal-finding Study of Abemaciclib in Heavily Pretreated Patients with Metastatic Castration-Resistant Prostate Cancer: Results from CYCLONE 1.
    Clin Cancer Res. 2024 Mar 21. doi: 10.1158/1078-0432.CCR-23-3436.
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  20. ANSELMINO N, Labanca E, Shepherd PDA, Dong J, et al
    Integrative molecular analyses of the MD Anderson prostate cancer patient-derived xenograft (MDA PCa PDX) series.
    Clin Cancer Res. 2024 Mar 15. doi: 10.1158/1078-0432.CCR-23-2438.
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    February 2024
  21. VELLKY JE, Kirkpatrick BJ, Gutgesell LC, Morales M, et al
    ERBB3 overexpression is enriched in diverse patient populations with castration-sensitive prostate cancer and is associated with a unique AR activity signature.
    Clin Cancer Res. 2024 Feb 2. doi: 10.1158/1078-0432.CCR-23-2161.
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  22. DORFF T, Horvath LG, Autio K, Bernard-Tessier A, et al
    A phase 1 study of acapatamab, a half-life extended, PSMA-targeting bispecific T-cell engager for metastatic castration-resistant prostate cancer.
    Clin Cancer Res. 2024 Feb 1. doi: 10.1158/1078-0432.CCR-23-2978.
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    January 2024
  23. HALABI S, Guo S, Park JJ, Nanus DM, et al
    The impact of circulating tumor cell HOXB13 RNA detection in men with metastatic castration-resistant prostate cancer treated with abiraterone or enzalutamide.
    Clin Cancer Res. 2024 Jan 18. doi: 10.1158/1078-0432.CCR-23-3017.
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  24. ABIDA W, Hahn AW, Shore N, Agarwal N, et al
    Phase 1 Study of ORIC-101, a Glucocorticoid Receptor Antagonist, in Combination with Enzalutamide in Patients with Metastatic Castration-Resistant Prostate Cancer Progressing on Enzalutamide.
    Clin Cancer Res. 2024 Jan 16. doi: 10.1158/1078-0432.CCR-23-3508.
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    September 2023
  25. CHAUDAGAR K, Hieromnimon HM, Kelley A, Labadie B, et al
    Suppression of tumor cell lactate-generating signaling pathways eradicates murine PTEN/p53-deficient aggressive-variant prostate cancer via macrophage phagocytosis.
    Clin Cancer Res. 2023 Sep 18. doi: 10.1158/1078-0432.CCR-23-1441.
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    August 2023
  26. GENG C, Zhang MC, Manyam GC, Vykoukal JV, et al
    SPOP mutations target STING1 signaling in prostate cancer and create therapeutic vulnerabilities to PARP inhibitor-induced growth suppression.
    Clin Cancer Res. 2023 Aug 15:CCR-23-1439. doi: 10.1158/1078-0432.CCR-23-1439.
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    July 2023
  27. CHEHRAZI-RAFFLE A, Tukachinsky H, Toye E, Sivakumar S, et al
    Unique spectrum of activating BRAF alterations in prostate cancer.
    Clin Cancer Res. 2023 Jul 21:CCR-23-1393. doi: 10.1158/1078-0432.CCR-23-1393.
    >> Share

  28. HWANG J, Shi X, Elliott A, Arnoff TE, et al
    Metastatic Prostate Cancers with BRCA2 versus ATM Mutations Exhibit Divergent Molecular Features and Clinical Outcomes.
    Clin Cancer Res. 2023;29:2702-2713.
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  29. FLESHNER NE, Sayyid RK, Hansen AR, Chin JLK, et al
    Neoadjuvant Cabazitaxel Plus Abiraterone/Leuprolide Acetate in High-Risk Prostate Cancer Patients: ACDC-RP Phase II Trial.
    Clin Cancer Res. 2023 Jul 13:CCR-23-0731. doi: 10.1158/1078-0432.CCR-23-0731.
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    June 2023
  30. MENSSOURI N, Poiraudeau L, Helissey C, Bigot L, et al
    Genomic profiling of metastatic castration-resistant prostate cancer samples resistant to androgen-receptor pathway inhibitors.
    Clin Cancer Res. 2023 Jun 26:CCR-22-3736. doi: 10.1158/1078-0432.CCR-22-3736.
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  31. POOK D, Geynisman DM, Carles J, de Braud F, et al
    A phase Ib, open-label study evaluating the safety and efficacy of ipatasertib plus rucaparib in patients with metastatic castration-resistant prostate cancer.
    Clin Cancer Res. 2023 Jun 20:CCR-22-2585. doi: 10.1158/1078-0432.CCR-22-2585.
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  32. SARTOR O
    Circulating Tumor DNA Biomarkers for Response Assessment in Prostate Cancer.
    Clin Cancer Res. 2023 Jun 2:OF1-OF3. doi: 10.1158/1078-0432.CCR-23-1043.
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    May 2023
  33. SARTOR O
    Circulating tumor DNA biomarkers for response assessment in prostate cancer.
    Clin Cancer Res. 2023 May 25:CCR-23-1043. doi: 10.1158/1078-0432.CCR-23-1043.
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  34. BHINDER B, Ferguson A, Sigouros M, Uppal M, et al
    The Immunogenomic Landscape of Neuroendocrine Prostate Cancer.
    Clin Cancer Res. 2023 May 24:CCR-22-3743. doi: 10.1158/1078-0432.CCR-22-3743.
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    April 2023
  35. ANTONARAKIS ES, Subudhi SK, Pieczonka CM, Karsh LI, et al
    Combination Treatment with Sipuleucel-T and Abiraterone Acetate or Enzalutamide for Metastatic Castration-Resistant Prostate Cancer: STAMP and STRIDE Trials.
    Clin Cancer Res. 2023 Apr 14:CCR-22-3832. doi: 10.1158/1078-0432.CCR-22-3832.
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    March 2023
  36. TOLMEIJER SH, Boerrigter E, Sumiyoshi T, Kwan EM, et al
    Early on-treatment changes in circulating tumor DNA fraction and response to enzalutamide or abiraterone in metastatic castration-resistant prostate cancer.
    Clin Cancer Res. 2023 Mar 30:CCR-22-2998. doi: 10.1158/1078-0432.CCR-22-2998.
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  37. SPERGER JM, Helzer KT, Stahlfeld CN, Jiang D, et al
    Expression and therapeutic targeting of Trop-2 in treatment resistant prostate cancer.
    Clin Cancer Res. 2023 Mar 20:CCR-22-1305. doi: 10.1158/1078-0432.CCR-22-1305.
    >> Share

  38. BIDKAR AP, Wang S, Bobba KN, Chan E, et al
    Treatment of prostate cancer with CD46 targeted 225Ac alpha particle radioimmunotherapy.
    Clin Cancer Res. 2023 Mar 14:CCR-22-3291. doi: 10.1158/1078-0432.CCR-22-3291.
    >> Share

  39. OMLIN A, Cathomas R, von Amsberg G, Reuter C, et al
    Randomized phase 2 Cabazitaxel dose individualization and Neutropenia prevention Trial (CAINTA) in patients with metastatic castration-resistant prostate cancer.
    Clin Cancer Res. 2023 Mar 14:CCR-22-3360. doi: 10.1158/1078-0432.CCR-22-3360.
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  40. GUPTA S, Halabi S, Yang Q, Roy A, et al
    PSMA-positive circulating tumor cell detection and outcomes with abiraterone or enzalutamide treatment in men with metastatic castrate resistant prostate cancer.
    Clin Cancer Res. 2023 Mar 10:CCR-22-3233. doi: 10.1158/1078-0432.CCR-22-3233.
    >> Share

  41. CHAUDAGAR K, Hieromnimon HM, Khurana R, Labadie B, et al
    Reversal of lactate and PD-1-mediated macrophage immunosuppression controls growth of PTEN/p53-deficient prostate cancer.
    Clin Cancer Res. 2023 Mar 2:CCR-22-3350. doi: 10.1158/1078-0432.CCR-22-3350.
    >> Share

  42. ROBERT C, Lebbe C, Lesimple T, Lundstrom E, et al
    Phase I Study of Androgen Deprivation Therapy in Combination with Anti-PD-1 in Melanoma Patients Pretreated with Anti-PD-1.
    Clin Cancer Res. 2023;29:858-865.
    >> Share

  43. CHEEMA AK, Li Y, Ventimiglia M, Kowalczyk K, et al
    Radiotherapy Induces Innate Immune Responses in Patients Treated for Prostate Cancers.
    Clin Cancer Res. 2023;29:921-929.
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    December 2022
  44. FALLAH J, Agrawal S, Gittleman H, Fiero MH, et al
    FDA Approval Summary: lutetium Lu 177 vipivotide tetraxetan for patients with metastatic castration-resistant prostate cancer.
    Clin Cancer Res. 2022 Dec 5:CCR-22-2875. doi: 10.1158/1078-0432.CCR-22-2875.
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    November 2022
  45. LIM EA, Bendell JC, Falchook GS, Bauer TM, et al
    Phase Ia/b, Open-Label, Multicenter Study of AZD4635 (an Adenosine A2A Receptor Antagonist) as Monotherapy or Combined with Durvalumab, in Patients with Solid Tumors.
    Clin Cancer Res. 2022;28:4871-4884.
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  46. QUINN Z, Leiby B, Sonpavde G, Choudhury AD, et al
    Phase I Study of Niraparib in Combination with Radium-223 for the Treatment of Metastatic Castrate Resistant Prostate Cancer.
    Clin Cancer Res. 2022 Nov 2. pii: 710187. doi: 10.1158/1078-0432.CCR-22-2526.
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  47. MATSUBARA N, de Bono J, Olmos D, Procopio G, et al
    Olaparib Efficacy in Patients with Metastatic Castration-resistant Prostate Cancer and BRCA1, BRCA2 or ATM Alterations Identified by Testing Circulating Tumor DNA.
    Clin Cancer Res. 2022 Nov 1. pii: 710156. doi: 10.1158/1078-0432.CCR-21-3577.
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    October 2022
  48. FENG E, Rydzewski NR, Zhang M, Lundberg A, et al
    Intrinsic Molecular Subtypes of Metastatic Castration-Resistant Prostate Cancer.
    Clin Cancer Res. 2022 Oct 19. pii: 709863. doi: 10.1158/1078-0432.CCR-22-2567.
    >> Share

  49. VAISHAMPAYAN UN, Thakur A, Chen W, Deol A, et al
    Phase II trial of Pembrolizumab and Anti-CD3 x Anti-HER2 Bispecific Antibody Armed Activated T Cells in Metastatic Castrate Resistant Prostate Cancer.
    Clin Cancer Res. 2022 Oct 18. pii: 709809. doi: 10.1158/1078-0432.CCR-22-1601.
    >> Share

  50. FENDLER WP, Pabst KM, Kessler L, Fragoso Costa P, et al
    Safety and Efficacy of 90Y-FAPI-46 Radioligand Therapy in Patients with Advanced Sarcoma and Other Cancer Entities.
    Clin Cancer Res. 2022;28:4346-4353.
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    September 2022
  51. PLYM A, Zhang Y, Stopsack KH, Jee YH, et al
    Family history of prostate and breast cancer integrated with a polygenic risk score identifies men at highest risk of dying from prostate cancer before age 75 years.
    Clin Cancer Res. 2022 Sep 14. pii: 709205. doi: 10.1158/1078-0432.CCR-22-1723.
    >> Share

  52. SWAMI U, Graf RP, Nussenzveig RH, Fisher V, et al
    SPOP mutations as a Predictive Biomarker for Androgen Receptor-Axis-Targeted Therapy in De Novo Metastatic Castration-Sensitive Prostate Cancer.
    Clin Cancer Res. 2022 Sep 11. pii: 709162. doi: 10.1158/1078-0432.CCR-22-2228.
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    August 2022
  53. CHI KN, Barnicle A, Sibilla C, Lai Z, et al
    Detection of BRCA1, BRCA2, and ATM Alterations in Matched Tumor Tissue and Circulating Tumor DNA in Patients with Prostate Cancer Screened in PROfound.
    Clin Cancer Res. 2022 Aug 31:OF1-OF11. doi: 10.1158/1078-0432.CCR-22-0931.
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    July 2022
  54. NGUYEN DT, Yang W, Renganathan A, Weimholt C, et al
    Acetylated HOXB13 Regulated Super Enhancer Genes Define Therapeutic Vulnerabilities of Castration-Resistant Prostate Cancer.
    Clin Cancer Res. 2022 Jul 18. pii: 707054. doi: 10.1158/1078-0432.CCR-21-3603.
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  55. AGGARWAL R, Starodub AN, Koh BD, Xing G, et al
    Phase 1b Study of the BET Inhibitor GS-5829 as Monotherapy and Combined with Enzalutamide in Patients with Metastatic Castration-Resistant Prostate Cancer.
    Clin Cancer Res. 2022 Jul 11. pii: 706956. doi: 10.1158/1078-0432.CCR-22-0175.
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  56. FISHER NC, Byrne RM, Leslie H, Wood C, et al
    Biological misinterpretation of transcriptional signatures in tumour samples can unknowingly undermine mechanistic understanding and faithful alignment with preclinical data.
    Clin Cancer Res. 2022 Jul 6. pii: 706888. doi: 10.1158/1078-0432.CCR-22-1102.
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  57. WANG T, Song W, Chen Y, Chen R, et al
    Correction: Flightless I Homolog Represses Prostate Cancer Progression through Targeting Androgen Receptor Signaling.
    Clin Cancer Res. 2022;28:2970.
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    June 2022
  58. SOWALSKY AG, Figueiredo I, Lis RT, Coleman I, et al
    Assessment of Androgen Receptor splice variant-7 as a biomarker of clinical response in castration-sensitive prostate cancer.
    Clin Cancer Res. 2022 Jun 13. pii: 704873. doi: 10.1158/1078-0432.CCR-22-0851.
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  59. CHAKRABORTY G, Nandakumar S, Hirani R, Nguyen B, et al
    The impact of PIK3R1 mutations and insulin-PI3K-glycolytic pathway regulation in prostate cancer.
    Clin Cancer Res. 2022 Jun 7. pii: 699404. doi: 10.1158/1078-0432.CCR-21-4272.
    >> Share

  60. CHOUDHURY AD, Higano CS, de Bono JS, Cook N, et al
    A Phase I Study Investigating AZD8186, a Potent and Selective Inhibitor of PI3Kbeta/delta, in Patients with Advanced Solid Tumors.
    Clin Cancer Res. 2022;28:2257-2269.
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    May 2022
  61. ZHAO N, Chopra S, Trepka K, Wang YH, et al
    CUB domain containing protein 1 (CDCP1) is a target for radioligand therapy in castration resistant prostate cancer including PSMA null disease.
    Clin Cancer Res. 2022 May 23. pii: 699115. doi: 10.1158/1078-0432.CCR-21-3858.
    >> Share

  62. COLEMAN IM, DeSarkar N, Morrissey C, Xin L, et al
    Therapeutic Implications for Intrinsic Phenotype Classification of Metastatic Castration Resistant Prostate Cancer.
    Clin Cancer Res. 2022 May 12. pii: 698880. doi: 10.1158/1078-0432.CCR-21-4289.
    >> Share

  63. SHEEHAN B, Neeb A, Buroni L, Paschalis A, et al
    Prostate Specific Membrane Antigen Expression and Response to DNA Damaging Agents in Prostate Cancer.
    Clin Cancer Res. 2022 May 12. pii: 698876. doi: 10.1158/1078-0432.CCR-21-4531.
    >> Share

    April 2022
  64. MARKOWSKI MC, Tutrone R, Pieczonka C, Barnette KG, et al
    A Phase 1b/2 Study of Sabizabulin, a Novel Oral Cytoskeleton Disruptor, in Men With Metastatic Castration-Resistant Prostate Cancer with Progression on an Androgen Receptor Targeting Agent.
    Clin Cancer Res. 2022 Apr 13. pii: 694403. doi: 10.1158/1078-0432.CCR-22-0162.
    >> Share

  65. SWEENEY CJ, Percent IJ, Babu S, Cultrera JL, et al
    Phase 1b/2 Study of Enzalutamide with Samotolisib (LY3023414) or Placebo in Patients with Metastatic Castration-Resistant Prostate Cancer.
    Clin Cancer Res. 2022 Apr 1. pii: 694115. doi: 10.1158/1078-0432.CCR-21-2326.
    >> Share

  66. WESTPHALEN CB, Fine AD, Andre F, Ganesan S, et al
    Pan-cancer Analysis of Homologous Recombination Repair-associated Gene Alterations and Genome-wide Loss-of-Heterozygosity Score.
    Clin Cancer Res. 2022;28:1412-1421.
    >> Share

    February 2022
  67. DE KOUCHKOVSKY I, Rao A, Carneiro BA, Zhang L, et al
    A phase Ib/II study of the CDK 4/6 inhibitor ribociclib in combination with docetaxel plus prednisone in metastatic castration-resistant prostate cancer.
    Clin Cancer Res. 2022 Feb 17. pii: 681559. doi: 10.1158/1078-0432.CCR-21-4302.
    >> Share

  68. SERRITELLA AV, Shevrin D, Heath EI, Wade JL, et al
    Phase I/II trial of enzalutamide and mifepristone, a glucocorticoid receptor antagonist, for metastatic castration-resistant prostate cancer.
    Clin Cancer Res. 2022 Feb 2. pii: 1078-0432.CCR-21-4049.
    >> Share

    January 2022
  69. HUSSAIN M, Corcoran C, Sibilla C, Fizazi K, et al
    Tumor Genomic Testing for >4000 Men with Metastatic Castration-resistant Prostate Cancer in the Phase III Trial PROfound (Olaparib).
    Clin Cancer Res. 2022 Jan 28. pii: 1078-0432.CCR-21-3940.
    >> Share

  70. DYLGJERI E, Kothari V, Shafi AA, Semenova G, et al
    A Novel Role for DNA-PK in Metabolism by Regulating Glycolysis in Castration Resistant Prostate Cancer.
    Clin Cancer Res. 2022 Jan 25. pii: 1078-0432.CCR-21-1846.
    >> Share

    December 2021
  71. ZHAO JL, Fizazi K, Saad F, Chi KN, et al
    The Effect of Corticosteroids on Prostate Cancer Outcome Following Treatment with Enzalutamide: A Multivariate Analysis of the Phase III AFFIRM Trial.
    Clin Cancer Res. 2021 Dec 29. pii: 1078-0432.CCR-21-1090.
    >> Share

  72. BERCHUCK JE, Baca SC, McClure HM, Korthauer K, et al
    Detecting neuroendocrine prostate cancer through tissue-informed cell-free DNA methylation analysis.
    Clin Cancer Res. 2021 Dec 14. pii: 1078-0432.CCR-21-3762.
    >> Share

    November 2021
  73. PENG S, Hu P, Xiao YT, Lu W, et al
    Single-cell analysis reveals EP4 as a target for restoring T cell infiltration and sensitizing prostate cancer to immunotherapy.
    Clin Cancer Res. 2021 Nov 5. pii: 1078-0432.CCR-21-0299.
    >> Share

  74. AL-UBAIDI FLT, Schultz N, Loseva O, Egevad L, et al
    Editor's Note: Castration Therapy Results in Decreased Ku70 Levels in Prostate Cancer.
    Clin Cancer Res. 2021;27:6066.
    >> Share

    October 2021
  75. DORFF TB, Narayan V, Forman SJ, Zang PD, et al
    Novel Redirected T Cell Immunotherapies for Advanced Prostate Cancer.
    Clin Cancer Res. 2021 Oct 21. pii: 1078-0432.CCR-21-1483.
    >> Share

  76. STOPSACK KH, Nandakumar S, Arora K, Nguyen B, et al
    Differences in prostate cancer genomes by self-reported race: Contributions of genetic ancestry, modifiable cancer risk factors, and clinical factors.
    Clin Cancer Res. 2021 Oct 19. pii: 1078-0432.CCR-21-2577.
    >> Share

  77. LOEHR A, Patnaik A, Campbell D, Shapiro J, et al
    Response to rucaparib in BRCA-mutant metastatic castration-resistant prostate cancer identified by genomic testing in the TRITON2 study.
    Clin Cancer Res. 2021 Oct 1. pii: 1078-0432.CCR-21-2199.
    >> Share

    September 2021
  78. ZHANG H, Orme JJ, Abraha F, Stish BJ, et al
    Phase II evaluation of Stereotactic Ablative Radiotherapy (SABR) and immunity in (11)C-Choline-PET/CT-identified oligometastatic castration-resistant prostate cancer.
    Clin Cancer Res. 2021 Sep 30. pii: 1078-0432.CCR-21-2510.
    >> Share

  79. MIZUNO K, Sumiyoshi T, Okegawa T, Terada N, et al
    Clinical impact of detecting low-frequency variants in cell-free DNA on treatment of castration-resistant prostate cancer.
    Clin Cancer Res. 2021 Sep 15. pii: 1078-0432.CCR-21-2328.
    >> Share

  80. JEONG IG, Lim B, Yun SC, Lim JH, et al
    Adjuvant Low-dose Statin Use after Radical Prostatectomy: The PRO-STAT Randomized Clinical Trial.
    Clin Cancer Res. 2021;27:5004-5011.
    >> Share

    August 2021
  81. MOSTAGHEL EA, Marck BT, Kolokythas O, Chew F, et al
    Circulating and intra-tumoral adrenal androgens correlate with response to abiraterone in men with castration resistant prostate cancer.
    Clin Cancer Res. 2021 Aug 18. pii: 1078-0432.CCR-21-1819.
    >> Share

    July 2021
  82. MURTOLA TJ, Siltari A
    Statins for prostate cancer: when and how much?
    Clin Cancer Res. 2021 Jul 19. pii: 1078-0432.CCR-21-1891.
    >> Share

  83. SARKER D, Dawson NA, Aparicio AM, Dorff TB, et al
    A Phase I, Open-Label, Dose-Finding Study of GSK2636771, a PI3Kbeta inhibitor, Administered with Enzalutamide in Patients with Metastatic Castration-Resistant Prostate Cancer.
    Clin Cancer Res. 2021 Jul 19. pii: 1078-0432.CCR-21-1115.
    >> Share

  84. BROWN LC, Halabi S, Schonhoft JD, Yang Q, et al
    Circulating Tumor Cell Chromosomal Instability and Neuroendocrine Phenotype by Immunomorphology and Poor Outcomes in Men with mCRPC Treated with Abiraterone or Enzalutamide.
    Clin Cancer Res. 2021;27:4077-4088.
    >> Share

  85. DE BONO JS, Fleming MT, Wang JS, Cathomas R, et al
    Phase I Study of MEDI3726: A Prostate-Specific Membrane Antigen-Targeted Antibody-Drug Conjugate, in Patients with mCRPC after Failure of Abiraterone or Enzalutamide.
    Clin Cancer Res. 2021;27:3602-3609.
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    June 2021
  86. TURNER PG, Jain S, Cole A, Grey A, et al
    Toxicity and efficacy of concurrent androgen deprivation therapy, pelvic radiotherapy, and radium-223 in patients with de-novo metastatic hormone sensitive prostate cancer.
    Clin Cancer Res. 2021 Jun 29. pii: 1078-0432.CCR-21-0685.
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  87. CALAGUA C, Ficial M, Jansen CS, Hirz T, et al
    A Subset of Localized Prostate Cancer Displays an Immunogenic Phenotype Associated with Losses of Key Tumor Suppressor Genes.
    Clin Cancer Res. 2021 Jun 24. pii: 1078-0432.CCR-21-0121.
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  88. TANG Z, Pilie PG, Geng C, Manyam GC, et al
    ATR inhibitor-induced CDK1-SPOP axis destabilizes PD-L1 and enhances cytotoxicity in prostate cancer.
    Clin Cancer Res. 2021 Jun 24. pii: 1078-0432.CCR-21-1010.
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  89. KIM DH, Sun D, Storck WK, Welker Leng KR, et al
    BET Bromodomain Inhibition Blocks an AR-Repressed, E2F1-Activated Treatment-Emergent Neuroendocrine Prostate Cancer Lineage Plasticity Program.
    Clin Cancer Res. 2021 Jun 18. pii: 1078-0432.CCR-20-4968.
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  90. SMITH MR, Thomas S, Gormley M, Chowdhury S, et al
    Blood Biomarker Landscape in Patients with High-Risk Nonmetastatic Castration-Resistant Prostate Cancer Treated with Apalutamide and Androgen-Deprivation Therapy as They Progress to Metastatic Disease.
    Clin Cancer Res. 2021 Jun 10. pii: 1078-0432.CCR-21-0358.
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  91. FONG L, Morris MJ, Sartor O, Higano CS, et al
    A Phase Ib Study of Atezolizumab with Radium-223 Dichloride in Men with Metastatic Castration-Resistant Prostate Cancer.
    Clin Cancer Res. 2021 Jun 9. pii: 1078-0432.CCR-21-0063.
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  92. ANNALA M, Taavitsainen S, Khalaf DJ, Vandekerkhove G, et al
    Evolution of castration-resistant prostate cancer in ctDNA during sequential androgen receptor pathway inhibition.
    Clin Cancer Res. 2021 Jun 3. pii: 1078-0432.CCR-21-1625.
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  93. HAWKEY NM, Armstrong AJ
    Liquid Biopsy: It's the Bloody Truth!
    Clin Cancer Res. 2021;27:2961-2963.
    >> Share

  94. HEGDE A, Jayaprakash P, Couillault CA, Piha-Paul S, et al
    A Phase I Dose-Escalation Study to Evaluate the Safety and Tolerability of Evofosfamide in Combination with Ipilimumab in Advanced Solid Malignancies.
    Clin Cancer Res. 2021;27:3050-3060.
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    May 2021
  95. HAMMER S, Schlicker A, Zitzmann-Kolbe S, Baumgart S, et al
    Darolutamide potentiates the antitumor efficacy of a PSMA-targeted thorium-227 conjugate (PSMA-TTC) by a dual mode-of-action in prostate cancer models.
    Clin Cancer Res. 2021 May 25. pii: 1078-0432.CCR-21-0342.
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  96. MUNN LL, Stylianopoulos T, Jain NK, Hardin CC, et al
    Vascular Normalization to Improve Treatment of COVID-19: Lessons from Treatment of Cancer.
    Clin Cancer Res. 2021;27:2706-2711.
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  97. KAWAMOTO K, Okino ST, Place RF, Urakami S, et al
    Editor's Note: Epigenetic Modifications of RASSF1A Gene through Chromatin Remodeling in Prostate Cancer.
    Clin Cancer Res. 2021;27:2665.
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    April 2021
  98. TRUE LD, Chen DL
    How accurately does PSMA inhibitor 18F-DCFPyL-PET-CT image prostate cancer?
    Clin Cancer Res. 2021 Apr 23. pii: 1078-0432.CCR-21-0749.
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  99. PRIVE BM, Peters SMB, Muselaers CHJ, van Oort IM, et al
    Lutetium-177-PSMA-617 in low-volume hormone sensitive metastatic prostate cancer, a prospective pilot study.
    Clin Cancer Res. 2021 Apr 21. pii: 1078-0432.CCR-20-4298.
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  100. MCKAY RR, Kwak L, Crowdis J, Sperger JM, et al
    Phase 2 multicenter study of enzalutamide in metastatic castration resistant prostate cancer to identify mechanisms driving resistance.
    Clin Cancer Res. 2021 Apr 13. pii: 1078-0432.CCR-20-4616.
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    March 2021
  101. WARNER E, Herberts C, Fu S, Yip S, et al
    BRCA2, ATM, and CDK12 Defects Differentially Shape Prostate Tumor Driver Genomics and Clinical Aggression.
    Clin Cancer Res. 2021;27:1650-1662.
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  102. CHAKRABORTY G, Patail NK, Hirani R, Nandakumar S, et al
    Attenuation of SRC Kinase Activity Augments PARP Inhibitor-mediated Synthetic Lethality in BRCA2-altered Prostate Tumors.
    Clin Cancer Res. 2021;27:1792-1806.
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  103. LIN L, Kane N, Kobayashi N, Kono EA, et al
    High-dose per Fraction Radiotherapy Induces Both Antitumor Immunity and Immunosuppressive Responses in Prostate Tumors.
    Clin Cancer Res. 2021;27:1505-1515.
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    January 2021
  104. RESCIGNO P, Gurel B, Pereira R, Crespo M, et al
    Characterizing CDK12-Mutated Prostate Cancers.
    Clin Cancer Res. 2021;27:566-574.
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