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    January 2021
  1. MAEDA H, Sasaki F, Morinaga Y, Kabayama M, et al
    Covering Post-Endoscopic Submucosal Dissection Ulcers in Miniature Swine with Hexanoyl (Hx:C6) Group-Modified Alkaline-Treated Gelatin Porous Film (HAG) Induces Proper Healing by Decreasing Inflammation and Fibrosis.
    Digestion. 2021;102:415-427.
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  2. ISHIDA T, Dohi O, Yamada S, Yasuda T, et al
    Clinical Outcomes of Vonoprazan-Treated Patients after Endoscopic Submucosal Dissection for Gastric Neoplasms: A Prospective Multicenter Observation Study.
    Digestion. 2021;102:386-396.
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    December 2020
  3. YATAGAI N, Ueyama H, Ikemura M, Uchida R, et al
    Clinicopathological and Endoscopic Features of Raspberry-Shaped Gastric Cancer in Helicobacter pylori-Uninfected Patients.
    Digestion. 2020 Dec 15:1-8. doi: 10.1159/000511907.
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    August 2020
  4. NORITA K, Asanuma K, Koike T, Okata T, et al
    Impaired Mucosal Integrity in Proximal Esophagus Is Involved in Development of Proton Pump Inhibitor-Refractory Nonerosive Reflux Disease.
    Digestion. 2020 Aug 12:1-11. doi: 10.1159/000508661.
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    February 2020
  5. MATSUNAGA T, Endo H, Takamori A, Shimada F, et al
    Lifestyle- and Comorbidity-Related Risk Factors Associated with Prescription of Gastric Acid Secretion Inhibitors to Japanese Patients Who Were Helicobacter pylori Negative and Had No Upper Gastrointestinal Lesions.
    Digestion. 2020 Feb 25:1-9. doi: 10.1159/000506153.
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  6. LIN L, Cui B, Deng Y, Jiang X, et al
    The Efficacy of Proton Pump Inhibitor in Cirrhotics with Variceal Bleeding: A Systemic Review and Meta-Analysis.
    Digestion. 2020 Feb 21:1-11. doi: 10.1159/000505059.
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  7. ABE Y, Koike T, Saito M, Okata T, et al
    The Ameliorating Effect of Switching to Vonoprazan: A Novel Potassium-Competitive Acid Blocker in Patients with Proton Pump Inhibitor Refractory Non-Erosive Reflux Disease.
    Digestion. 2020 Feb 14:1-9. doi: 10.1159/000506152.
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    January 2020
  8. SHINOZAKI S, Kobayashi Y, Osawa H, Sakamoto H, et al
    Effectiveness and Safety of Vonoprazan versus Proton Pump Inhibitors for Second-Line Helicobacter pylori Eradication Therapy: Systematic Review and Meta-Analysis.
    Digestion. 2020 Jan 8:1-7. doi: 10.1159/000504939.
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  9. MIZUNO H, Nishino M, Yamada K, Kamiyamamoto S, et al
    Efficacy of Vonoprazan for 48-Week Maintenance Therapy of Patients with Healed Reflux Esophagitis.
    Digestion. 2020;101:411-421.
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    December 2019
  10. HOJO M, Nagahara A, Hahm KB, Iwakiri R, et al
    Management of Gastroesophageal Reflux Disease in Asian Countries: Results of a Questionnaire Survey.
    Digestion. 2019 Dec 4:1-14. doi: 10.1159/000504749.
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    November 2019
  11. NAKATA R, Nagami Y, Hashimoto A, Sakai T, et al
    Successful Eradication of Helicobacter pylori Could Prevent Metachronous Gastric Cancer: A Propensity Matching Analysis.
    Digestion. 2019 Nov 1:1-10. doi: 10.1159/000504132.
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    October 2019
  12. HAMADA S, Ihara E, Ikeda H, Muta K, et al
    Clinical Characterization of Vonoprazan-Refractory Gastroesophageal Reflux Disease.
    Digestion. 2019 Oct 2:1-8. doi: 10.1159/000503340.
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    September 2019
  13. UENO T, Suzuki H, Hirose M, Shida T, et al
    Influence of Living Environment during Childhood on Helicobacter pylori Infection in Japanese Young Adults.
    Digestion. 2019 Sep 24:1-6. doi: 10.1159/000502574.
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  14. SAKAE H, Iwamuro M, Okamoto Y, Obayashi Y, et al
    Evaluation of the Usefulness and Convenience of the Kyoto Classification of Gastritis in the Endoscopic Diagnosis of the Helicobacter pylori Infection Status.
    Digestion. 2019 Sep 19:1-8. doi: 10.1159/000502573.
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  15. KUSANO C, Gotoda T, Ikehara H, Suzuki S, et al
    The Accuracy of the Serum Antibody Test for Helicobacter pylori Infection among Junior High School Students.
    Digestion. 2019 Sep 10:1-6. doi: 10.1159/000502900.
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    August 2019
  16. FURUTA T, Yamade M, Kagami T, Uotani T, et al
    Dual Therapy with Vonoprazan and Amoxicillin Is as Effective as Triple Therapy with Vonoprazan, Amoxicillin and Clarithromycin for Eradication of Helicobacter pylori.
    Digestion. 2019 Aug 21:1-9. doi: 10.1159/000502287.
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  17. IINO C, Shimoyama T, Chinda D, Sakuraba H, et al
    Influence of Helicobacter pylori Infection and Atrophic Gastritis on the Gut Microbiota in a Japanese Population.
    Digestion. 2019 Aug 8:1-11. doi: 10.1159/000500634.
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  18. MORI H, Suzuki H, Matsuzaki J, Masaoka T, et al
    10-Year Trends in Helicobacter pylori Eradication Rates by Sitafloxacin-Based Third-Line Rescue Therapy.
    Digestion. 2019 Aug 6:1-7. doi: 10.1159/000501610.
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    July 2019
  19. ABE Y, Koike T, Saito M, Okata T, et al
    Influence of the pH Value of Refluxate and Proximal Extent on Heartburn Perception in Patients with Proton Pump Inhibitor-Refractory Non-Erosive Reflux Disease.
    Digestion. 2019 Jul 29:1-7. doi: 10.1159/000500133.
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  20. ONO S, Dohi O, Yagi N, Sanomura Y, et al
    Accuracies of Endoscopic Diagnosis of Helicobacter pylori-Gastritis: Multicenter Prospective Study Using White Light Imaging and Linked Color Imaging.
    Digestion. 2019 Jul 23:1-7. doi: 10.1159/000501634.
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  21. NISHIDA T, Tsujii Y, Okamoto A, Tomita R, et al
    A Triple-Drug Blister-Packaged Drug with Vonoprazan Improves First-Line Eradication of Helicobacter pylori in Elderly Patients: A Retrospective Propensity Score-Matched Cohort Study.
    Digestion. 2019 Jul 9:1-7. doi: 10.1159/000501608.
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    June 2019
  22. DEGUCHI H, Uda A, Murakami K
    Current Status of Helicobacter pylori Diagnosis and Eradication Therapy in Japan Using a Nationwide Database.
    Digestion. 2019 Jun 19:1-9. doi: 10.1159/000500819.
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  23. KNOOP RF, Petzold G, Amanzada A, Bremer SCB, et al
    Testing of Helicobacter pylori by Endoscopic Biopsy: The Clinical Dilemma of Suppressive Conditions.
    Digestion. 2019 Jun 19:1-5. doi: 10.1159/000501270.
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    May 2019
  24. GONG EJ, Kim DH, Ahn JY, Na HK, et al
    Effects of Proton Pump Inhibitor on the Distribution of Helicobacter pylori and Associated Gastritis in Patients with Gastric Atrophy.
    Digestion. 2019 May 8:1-8. doi: 10.1159/000499424.
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    April 2019
  25. NABETA H, Shinozaki S, Abe Y, Koyanagi R, et al
    A Potassium-Competitive Acid Blocker-Based Regimen as Second-Line Therapy Improves Helicobacter pylori Eradication.
    Digestion. 2019 Apr 16:1-7. doi: 10.1159/000499857.
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  26. TSUDA M, Kato M, Ono S, Matsuda K, et al
    Changes of Dyspeptic Symptom after Successful Eradication in Helicobacter pylori-Associated Dyspepsia.
    Digestion. 2019 Apr 16:1-9. doi: 10.1159/000497432.
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  27. INUI M, Ohwada S, Inui Y, Kondo Y, et al
    Evaluating the Accuracy of the Endoscopic ABC Classification System in Diagnosing Helicobacter pylori-Infected Gastritis.
    Digestion. 2019 Apr 12:1-10. doi: 10.1159/000498966.
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    March 2019
  28. AKIYAMA J, Hosaka H, Kuribayashi S, Moriyasu S, et al
    Efficacy of Vonoprazan, a Novel Potassium-Competitive Acid Blocker, in Patients with Proton Pump Inhibitor-Refractory Acid Reflux.
    Digestion. 2019 Mar 21:1-10. doi: 10.1159/000497775.
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  29. OKUNO H, Suzuki S, Watanabe H, Kusano C, et al
    Histological Features of Gastric Mucosa Serologically Diagnosed as Gastric Atrophy without Helicobacter pylori Infection.
    Digestion. 2019 Mar 14:1-10. doi: 10.1159/000498940.
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  30. SAKATA Y, Tsuruoka N, Takedomi H, Akutagawa T, et al
    A Study on the Status of Proton Pump Inhibitor Prescriptions Using Diagnosis Procedure Combination Data in Japan.
    Digestion. 2019 Mar 6:1-8. doi: 10.1159/000498967.
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    January 2019
  31. KAWAMURA Y, Funaki Y, Yoshimine T, Tamura Y, et al
    Characteristics and Predictive Factor of Helicobacter pylori-Associated Functional Dyspepsia in Japanese Patients.
    Digestion. 2019 Jan 10:1-9. doi: 10.1159/000496101.
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  32. HATA K, Ito M, Boda T, Kotachi T, et al
    Gastric Cancer with Submucosal Invasion after Successful Helicobacter pylori Eradication: A Propensity Score-Matched Analysis of Patients with Annual Patient Endoscopic Survey.
    Digestion. 2019;99:59-65.
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  33. OMORI J, Fujimori S, Kosugi Y, Yukiko K, et al
    Pilot Study Indicates Helicobacter pylori Infection May Induce Small Intestinal Mucosal Injury.
    Digestion. 2019;99:66-71.
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  34. SAKATA Y, Tsuruoka N, Shimoda R, Yamamoto K, et al
    Comparison of Clinical Characteristics of Patients with Acute Esophageal Mucosal Lesion and those with Severe Reflux Esophagitis.
    Digestion. 2019;99:275-282.
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    November 2018
  35. FUJIWARA Y, Hashimoto A, Uemura R, Sawada A, et al
    Optimal Biopsy Protocol to Evaluate Histological Effectiveness of Proton Pump Inhibitor Therapy in Patients with Eosinophilic Esophagitis.
    Digestion. 2018 Nov 8:1-8. doi: 10.1159/000494253.
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    September 2018
  36. YOSHIMINE T, Funaki Y, Kawamura Y, Tamura Y, et al
    Convenient Method of Measuring Baseline Impedance for Distinguishing Patients with Functional Heartburn from those with Proton Pump Inhibitor-Resistant Endoscopic Negative Reflux Disease.
    Digestion. 2018 Sep 4:1-9. doi: 10.1159/000490790.
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  37. TAKARA Y, Endo H, Nakano R, Kawachi K, et al
    Smoking and Drinking Did Not Increase the Failure of Therapeutic Helicobacter pylori Eradication by Vonoprazan, Clarithromycin, and Amoxicillin.
    Digestion. 2018 Sep 4:1-7. doi: 10.1159/000490889.
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    July 2018
  38. MATSUDA R, Yamamichi N, Shimamoto T, Sumida H, et al
    Gastroesophageal Reflux Disease-Related Disorders of Systemic Sclerosis Based on the Analysis of 66 Patients.
    Digestion. 2018;98:201-208.
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    June 2018
  39. AKAZAWA Y, Ueyama H, Yao T, Komori H, et al
    Usefulness of Demarcation of Differentiated-Type Early Gastric Cancers after Helicobacter pylori Eradication by Magnifying Endoscopy with Narrow-Band Imaging.
    Digestion. 2018;98:175-184.
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  40. BOLTIN D, Schmilovitz-Weiss H, Gingold-Belfer R, Leibovitzh H, et al
    Temporal Trends in Helicobacter pylori Eradication Success in a Test-and-Treat Population.
    Digestion. 2018;98:169-174.
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    May 2018
  41. YAMADA A, Kaise M, Inoshita N, Toba T, et al
    Characterization of Helicobacter pylori-Naive Early Gastric Cancers.
    Digestion. 2018;98:127-134.
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    April 2018
  42. TSUTSUMI K, Kusano C, Suzuki S, Gotoda T, et al
    Diagnostic Accuracy of Latex Agglutination Turbidimetric Immunoassay in Screening Adolescents for Helicobacter pylori Infection in Japan.
    Digestion. 2018;98:75-80.
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  43. WINKELSETT L, Malfertheiner P, Wex T, Kandulski A, et al
    Mucosal Two-Step Pathogenesis in Gastroesophageal Reflux Disease: Repeated Weakly Acidic Stimulation and Activation of Protease-Activated Receptor-2 on Mucosal Interleukin-8 Secretion.
    Digestion. 2018;98:19-25.
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  44. KOTACHI T, Ito M, Boda T, Kiso M, et al
    Clinical Significance of Reddish Depressed Lesions Observed in the Gastric Mucosa after Helicobacter pylori Eradication.
    Digestion. 2018;98:48-55.
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    March 2018
  45. YAMADA S, Tomatsuri N, Kawakami T, Nakatsugawa Y, et al
    Helicobacter pylori Eradication Therapy Ameliorates Latent Digestive Symptoms in Chronic Atrophic Gastritis.
    Digestion. 2018;97:333-339.
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  46. KODAMA M, Okimoto T, Mizukami K, Abe H, et al
    Endoscopic and Immunohistochemical Characteristics of Gastric Cancer with versus without Helicobacter Pylori Eradication.
    Digestion. 2018;97:288-297.
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    February 2018
  47. MATSUURA S, Sakata Y, Tsuruoka N, Miyahara K, et al
    Outcomes of Patients Undergoing Endoscopic Hemostasis for the Upper Gastrointestinal Bleeding Were Not Influenced by the Timing of Hospital Emergency Visits: A Situation Prevailing in Japan.
    Digestion. 2018;97:260-266.
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  48. KOJIMA Y, Takeuchi T, Sanomura M, Higashino K, et al
    Does the Novel Potassium-Competitive Acid Blocker Vonoprazan Cause More Hypergastrinemia than Conventional Proton Pump Inhibitors? A Multicenter Prospective Cross-Sectional Study.
    Digestion. 2018;97:70-75.
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  49. MATSUMURA T, Arai M, Ishigami H, Fujie M, et al
    Evaluation of Esophageal Mucosal Integrity in Patients with Gastroesophageal Reflux Disease.
    Digestion. 2018;97:31-37.
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    January 2018
  50. OZAKI H, Harada S, Takeuchi T, Kawaguchi S, et al
    Vonoprazan, a Novel Potassium-Competitive Acid Blocker, Should Be Used for the Helicobacter pylori Eradication Therapy as First Choice: A Large Sample Study of Vonoprazan in Real World Compared with Our Randomized Control Trial Using Second-Generation
    Digestion. 2018;97:212-218.
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  51. SAHARA S, Sugimoto M, Ichikawa H, Kagami T, et al
    Efficacy of Reduced Dosage of Amoxicillin in an Eradication Therapy for Helicobacter pylori Infection in Patients on Hemodialysis: A Randomized Controlled Trial.
    Digestion. 2018;97:163-169.
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  52. SHIOTANI A, Katsumata R, Gouda K, Fukushima S, et al
    Hypergastrinemia in Long-Term Use of Proton Pump Inhibitors.
    Digestion. 2018;97:154-162.
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  53. NAITO Y, Kashiwagi K, Takagi T, Andoh A, et al
    Intestinal Dysbiosis Secondary to Proton-Pump Inhibitor Use.
    Digestion. 2018;97:195-204.
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  54. YAMASAKI A, Yoshio T, Muramatsu Y, Horiuchi Y, et al
    Vonoprazan is Superior to Rabeprazole for Healing Endoscopic Submucosal Dissection: Induced Ulcers.
    Digestion. 2018;97:170-176.
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  55. XU Y, Jia J, Xie C, Wu Y, et al
    Transient Receptor Potential Ankyrin 1 and Substance P Mediate the Development of Gastric Mucosal Lesions in a Water Immersion Restraint Stress Rat Model.
    Digestion. 2018;97:228-239.
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  56. UMEZAWA M, Kawami N, Hoshino S, Hoshikawa Y, et al
    Efficacy of On-Demand Therapy Using 20-mg Vonoprazan for Mild Reflux Esophagitis.
    Digestion. 2018;97:309-315.
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    October 2017
  57. HORIUCHI Y, Fujisaki J, Ishizuka N, Omae M, et al
    Study on Clinical Factors Involved in Helicobacter pylori-Uninfected, Undifferentiated-Type Early Gastric Cancer.
    Digestion. 2017;96:213-219.
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    August 2017
  58. CHINDA D, Shimoyama T, Iino C, Matsuzaka M, et al
    Decrease of Estradiol and Several Lifestyle Factors, but Not Helicobacter pylori Infection, Are Significant Risks for Osteopenia in Japanese Females.
    Digestion. 2017;96:103-109.
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    July 2017
  59. OHTSU T, Takagi A, Uemura N, Inoue K, et al
    The Ameliorating Effect of Lactobacillus gasseri OLL2716 on Functional Dyspepsia in Helicobacter pylori-Uninfected Individuals: A Randomized Controlled Study.
    Digestion. 2017;96:92-102.
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    June 2017
  60. YAMASHITA H, Kanamori A, Kano C, Hashimura H, et al
    The Effects of Switching to Vonoprazan, a Novel Potassium-Competitive Acid Blocker, on Gastric Acidity and Reflux Patterns in Patients with Erosive Esophagitis Refractory to Proton Pump Inhibitors.
    Digestion. 2017;96:52-59.
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  61. FUNAKI Y, Kaneko H, Kawamura Y, Yoshimine T, et al
    Impact of Comorbid Irritable Bowel Syndrome on Treatment Outcome in Non-Erosive Reflux Disease on Long-Term Proton Pump Inhibitor in Japan.
    Digestion. 2017;96:39-45.
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  62. KOTACHI T, Ito M, Yoshihara M, Boda T, et al
    Serological Evaluation of Gastric Cancer Risk Based on Pepsinogen and Helicobacter pylori Antibody: Relationship to Endoscopic Findings.
    Digestion. 2017;95:314-318.
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  63. YAMAGUCHI D, Sakata Y, Yoshida H, Furukawa NE, et al
    Effectiveness of Endoscopic Hemostasis with Soft Coagulation for Non-Variceal Upper Gastrointestinal Bleeding over a 12-Year Period.
    Digestion. 2017;95:319-326.
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    May 2017
  64. SUGIMOTO M, Sahara S, Ichikawa H, Sakao Y, et al
    Natural Course of Helicobacter pylori Infection in Japanese Hemodialysis Patients.
    Digestion. 2017;95:302-309.
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  65. OKUYAMA M, Nakahara K, Iwakura N, Hasegawa T, et al
    Factors Associated with Potassium-Competitive Acid Blocker Non-Response in Patients with Proton Pump Inhibitor-Refractory Gastroesophageal Reflux Disease.
    Digestion. 2017;95:281-287.
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    March 2017
  66. KISHIKAWA H, Kimura K, Ito A, Arahata K, et al
    Cutoff Pepsinogen Level for Predicting Unintendedly Eradicated Cases of Helicobacter pylori Infection in Subjects with Seemingly Normal Pepsinogen Levels.
    Digestion. 2017;95:229-236.
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  67. KASAMATSU S, Matsumura T, Ohta Y, Hamanaka S, et al
    The Effect of Ineffective Esophageal Motility on Gastroesophageal Reflux Disease.
    Digestion. 2017;95:221-228.
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  68. MAJIMA A, Handa O, Naito Y, Dohi O, et al
    Early-Stage Gastric Cancer Can Be Found in Improved Atrophic Mucosa over Time from Successful Helicobacter pylori Eradication.
    Digestion. 2017;95:194-200.
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    February 2017
  69. HOSHINO S, Kawami N, Takenouchi N, Umezawa M, et al
    Efficacy of Vonoprazan for Proton Pump Inhibitor-Resistant Reflux Esophagitis.
    Digestion. 2017;95:156-161.
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  70. KAWAMI N, Takenouchi N, Umezawa M, Hoshino S, et al
    Pathogenesis of Double-Dose Proton Pump Inhibitor-Resistant Non-Erosive Reflux Disease, and Mechanism of Reflux Symptoms and Gastric Acid Secretion-Suppressive Effect in the Presence or Absence of Helicobacter pylori Infection.
    Digestion. 2017;95:140-145.
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    January 2017
  71. OVERBY A, Murayama SY, Michimae H, Suzuki H, et al
    Prevalence of Gastric Non-Helicobacter pylori-Helicobacters in Japanese Patients with Gastric Disease.
    Digestion. 2017;95:61-66.
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    December 2016
  72. TSUJIMAE M, Yamashita H, Hashimura H, Kano C, et al
    A Comparative Study of a New Class of Gastric Acid Suppressant Agent Named Vonoparazan versus Esomeprazole for the Eradication of Helicobacter pylori.
    Digestion. 2016;94:240-246.
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    January 2016
  73. TAKESHITA E, Sakata Y, Hara M, Akutagawa K, et al
    Higher Frequency of Reflux Symptoms and Acid-Related Dyspepsia in Women than Men Regardless of Endoscopic Esophagitis: Analysis of 3,505 Japanese Subjects Undergoing Medical Health Checkups.
    Digestion. 2016;93:266-71.
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