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Periodontology

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Articles published in
PLoS One
    January 2026
  1. XU M, Shi J, Wang Y, Wu J, et al
    Exploring the role of the key gene TNFAIP3 between periodontitis and influenza A through bioinformatic analysis and molecular docking.
    PLoS One. 2026;21:e0340882.
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  2. ZHANG S, Liu SY, Wang Q, Suo YX, et al
    Temporal trends and health inequalities in global, regional, and national years lived with disability of severe periodontitis from 1990 to 2021.
    PLoS One. 2026;21:e0337994.
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  3. SI C, Wu X, Cheng H, Jiang W, et al
    The immunopathological crosstalk of diabetic periodontitis: Single-cell insights into monocyte dysregulation.
    PLoS One. 2026;21:e0341333.
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  4. ARMIJOS BRIONES M, Ayala Aguirre PE, Benitez Sellan PL, Lanata-Flores A, et al
    Study protocol: Dental and periodontal characteristics of older adults in Atahualpa, Ecuador within the Atahualpa Project cohort.
    PLoS One. 2026;21:e0337166.
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  5. LUCAS C, Baxter D, Deeley K, Shah N, et al
    Genetic variants associated with systemic inflammatory disease associate with temporomandibular symptoms with or without periodontitis.
    PLoS One. 2026;21:e0328855.
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    January 2025
  6. TAJIK Z, Mehrafarid H, Bayani M, Almasi-Hashiani A, et al
    Comparison of visfatin levels before and after non-surgical periodontal therapy: A systematic review and meta-analysis.
    PLoS One. 2025;20:e0315035.
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  7. FIGUEIREDO NC, Piacsek M, Montalvany-Antonucci CC, Santos MS, et al
    Deletion of kinin receptor B2 enhances orthodontic tooth movement and alveolar bone remodeling.
    PLoS One. 2025;20:e0318436.
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  8. PEREZ A, Lagravere M, Miron Stefani C, Nasr Esfahani A, et al
    Partnering with periodontal patients and care providers to establish research priorities for patient engagement in specialized periodontal care: A study protocol.
    PLoS One. 2025;20:e0319841.
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  9. CHOPRA A, Song J, Weiner Rd J, Beule D, et al
    Genetic analysis of cis-enhancers associated with bone mineral density and periodontitis in the gene SOST.
    PLoS One. 2025;20:e0319259.
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  10. LUO R, Liang Z, Chen H, Bao D, et al
    Potential diagnostic markers and therapeutic targets for DM2 and periodontitis based on bioinformatics analysis.
    PLoS One. 2025;20:e0320061.
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  11. KATTEL B, Kumar A, Giri AK, Acharya P, et al
    Awareness of periodontitis and its relationship with systemic health among undergraduate medical students at a teaching hospital in Nepal: A cross-sectional study.
    PLoS One. 2025;20:e0321315.
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  12. ZHAO B, Li R
    Methylome and transcriptome analyses reveal HLA-DMB's contribution to periodontitis development.
    PLoS One. 2025;20:e0319055.
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  13. SONG Q, Zhang H, Su Y, Song J, et al
    The link between periodontitis and atherosclerotic cardiovascular disease in non-Hispanic White adults: NHANES 1999 to 2014.
    PLoS One. 2025;20:e0321220.
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  14. DE OLIVEIRA MONTEIRO AB, Honnef LR, Dias de Oliveira JM, Pauletto P, et al
    Prevalence of periodontitis in adolescents: A systematic review protocol.
    PLoS One. 2025;20:e0321993.
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  15. AL-MUTAIRI RS, Almohaimeed B
    Assessment of awareness level about consequences of missing teeth in Qassim region, Saudi Arabia.
    PLoS One. 2025;20:e0322325.
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  16. SEKAR P, Rizvi Z, Abdullah N, Samsudin AR, et al
    Oral microbiota interactions with titanium implants: A pilot in-vivo and in-vitro study on the impact of peri-implantitis.
    PLoS One. 2025;20:e0321428.
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  17. CUI X, Martinez Luna AA, Gillone A, Wu Q, et al
    Correlation between pre-extraction periodontal diagnosis and peri-implant microbiome for patients treated with implant-retained overdenture - A retrospective cohort pilot study.
    PLoS One. 2025;20:e0325711.
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  18. LIU Y, Kong G, Meng F, Guo C, et al
    Radiographic signature in apical periodontitis improves prediction of apical lesion healing through survival prediction model.
    PLoS One. 2025;20:e0327970.
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  19. CHENG LJ, Dong SY, Ni XF, Mei L, et al
    Effect of the TIM-3/Gal-9 signaling pathway on macrophage polarization in peri-implantitis.
    PLoS One. 2025;20:e0328258.
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  20. GAO S, Mu C, Feng J, Sun X, et al
    MiR-146a participates in regulating the progression of periodontitis through the Wnt/beta-catenin signaling pathway.
    PLoS One. 2025;20:e0330739.
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  21. WU Z, Zhang F, Wang Y, Liu C, et al
    Revealing potential interfering genes between abdominal aortic aneurysm and periodontitis through machine learning and bioinformatics analysis.
    PLoS One. 2025;20:e0329592.
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  22. MILINKOVIC I, Vuckovic M, Nikolic N, Carkic J, et al
    Exploring local adjuvant antibiotics as viable alternative to systemic antibiotics in non-surgical periodontal therapy: Clinical, immunological and microbiological insights.
    PLoS One. 2025;20:e0333342.
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  23. CHIANG MC, Chang CC, Lee CY, Yeh CC, et al
    Risk of atopic dermatitis in periodontitis patients with and without dental scaling: A retrospective cohort study.
    PLoS One. 2025;20:e0333877.
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  24. TULI P, Kolte AP, Kolte RA, Lathiya VN, et al
    Effectiveness of vestibular incision subperiosteal tunnel access (VISTA) technique with or without A-PRF in treatment of multiple adjacent gingival recession defects (MAGRD): A 12 months CBCT study.
    PLoS One. 2025;20:e0338823.
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    January 2024
  25. DUARTE PM, Gurgel BCV, Miranda TS, Sardenberg J, et al
    Distinctive genes and signaling pathways associated with type 2 diabetes-related periodontitis: Preliminary study.
    PLoS One. 2024;19:e0296925.
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  26. SREDOJEVIC S, Colak D, Gaspersic R, Pavlov Dolijanovic S, et al
    Periodontal health status in systemic sclerosis patients: Systematic review and meta-analysis.
    PLoS One. 2024;19:e0291078.
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  27. WU J, Li D, Lin M
    YouTube as an information source for bleeding gums: A quantitative and qualitative analysis.
    PLoS One. 2024;19:e0298597.
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  28. ROCA C, Alkhateeb AA, Deanhardt BK, Macdonald JK, et al
    Saliva sampling method influences oral microbiome composition and taxa distribution associated with oral diseases.
    PLoS One. 2024;19:e0301016.
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  29. ALAM N, Mariam W
    Impact of tobacco habits on poor oral health status among bone-factory workers in a low literacy city in India: A cross-sectional study.
    PLoS One. 2024;19:e0299594.
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  30. GHANEM AS, Nemeth O, More M, Nagy AC, et al
    Role of oral health in heart and vascular health: A population-based study.
    PLoS One. 2024;19:e0301466.
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  31. WUOKKO-LANDEN A, Valimaa H, Blomgren K, Suomalainen A, et al
    Dental findings frequently overlooked in sinus computed tomography reports.
    PLoS One. 2024;19:e0299489.
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  32. CHEN X, Niu W, Hu G, Chen C, et al
    Cost-effectiveness and cost-utility analyses of three different gargles in the treatment of chronic periodontitis.
    PLoS One. 2024;19:e0302592.
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  33. TAMADA Y, Kusama T, Ono S, Maeda M, et al
    Validity of claims-based definition of number of remaining teeth in Japan: Results from the Longevity Improvement and Fair Evidence Study.
    PLoS One. 2024;19:e0299849.
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  34. WU X
    Association between weight-adjusted-waist index and periodontitis risk: A cross-sectional study.
    PLoS One. 2024;19:e0302137.
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  35. WINCKLER K, Bukkehave KH, Tarnow L, Iversen PB, et al
    The prevention of adverse pregnancy outcomes by periodontal treatment during pregnancy (PROBE) intervention study-A controlled intervention study: Protocol paper.
    PLoS One. 2024;19:e0302010.
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  36. SHEN L, Niu D, Deng G
    Causal relationship between periodontal disease-related phenotype and knee osteoarthritis: A two-sample mendelian randomization analysis.
    PLoS One. 2024;19:e0304117.
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  37. FOLAYAN MO, Olagunju MT, Abodunrin OR, Alade OT, et al
    A scoping review on the use of traditional medicine and oral health in Africa.
    PLoS One. 2024;19:e0297570.
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  38. OZKAL EMINOGLU D, Arabaci T, Oztas Sahiner GA
    The effect of titanium-platelet rich fibrin on periodontal intrabony defects: A randomized controlled split-mouth clinical study.
    PLoS One. 2024;19:e0304970.
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  39. FERREIRA RO, Dos Santos VRN, Matos Sousa JM, Peinado BRR, et al
    Physical training minimizes immunological dysfunction, oxidative stress and tissue destruction on experimental periodontitis in rats.
    PLoS One. 2024;19:e0303374.
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  40. XU L, Liu Y, Zhao C, Wang J, et al
    Association between weight-adjusted waist index and periodontitis: A population-based study.
    PLoS One. 2024;19:e0305010.
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  41. STAM AJ, Groenewegen H, Vissink A, Wensing AMJ, et al
    Periodontal inflammation as a potential driver of HIV low level viremia.
    PLoS One. 2024;19:e0305641.
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  42. ALKHATEEB AA, Mancl LA, Ramos KJ, Rothen ML, et al
    The association between cystic fibrosis-related diabetes and periodontitis in adults: A pilot cross-sectional study.
    PLoS One. 2024;19:e0305975.
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  43. COSTA AA, Cota LOM, Esteves Lima RP, Oliveira AMSD, et al
    The association between periodontitis and the impact of oral health on the quality of life of individuals with psoriasis and psoriatic arthritis.
    PLoS One. 2024;19:e0301158.
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  44. DEINZER R, Weik U, Eidenhardt Z, Leufkens D, et al
    Manual toothbrushing techniques for plaque removal and the prevention of gingivitis-A systematic review with network meta-analysis.
    PLoS One. 2024;19:e0306302.
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  45. CONCEICAO SDS, Batista JET, Cruz SSD, Gomes-Filho IS, et al
    Systematic review to evaluate accuracy studies of the diagnostic criteria for periodontitis in pregnant women.
    PLoS One. 2024;19:e0304758.
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  46. LEE SY
    Association between gingivitis, tooth loss and cardiovascular risk: Insights from a 10-year nationwide cohort study of 3.7 million Koreans.
    PLoS One. 2024;19:e0308250.
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  47. CHIU CY, Yuh DY, Yeh LC, Lin IJ, et al
    Association between geniquin therapy and the risk of developing periodontal disease in patients with primary Sjogren's syndrome: A population-based cohort study from Taiwan.
    PLoS One. 2024;19:e0305130.
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  48. KONDO M, Ishigami M, Omoda M, Takeshita M, et al
    Association between the number of existing teeth and maintenance dialysis therapy: A cross-sectional study of adult male dentists.
    PLoS One. 2024;19:e0309012.
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  49. BAI Y, Qin S, Lu B, Wang W, et al
    Comparison of the efficacy of seven non-surgical methods combined with mechanical debridement in peri-implantitis and peri-implant mucositis: A network meta-analysis.
    PLoS One. 2024;19:e0305342.
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  50. GAO C, Iles M, Larvin H, Bishop DT, et al
    Genome-wide association studies on periodontitis: A systematic review.
    PLoS One. 2024;19:e0306983.
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  51. LYU J, Zhang Y, Zhou R, Ding C, et al
    The effect of periodontal treatments on endothelial function in degrees of periodontitis patients: A systematic review and meta-analysis.
    PLoS One. 2024;19:e0308793.
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  52. BAI J, Zhou C, Liu Y, Ding M, et al
    Relationship between serum uric acid levels and periodontitis-A cross-sectional study.
    PLoS One. 2024;19:e0310243.
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  53. ALHAFFAR S, Yalamanchi S, Shukla A
    Association of self-reported periodontal disease and inequities with long haul COVID-19.
    PLoS One. 2024;19:e0311644.
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  54. FRAZAO DR, Matos-Souza JM, Dos Santos VRN, Nazario RMF, et al
    Minocycline reduces alveolar bone loss and bone damage in Wistar rats with experimental periodontitis.
    PLoS One. 2024;19:e0309390.
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  55. LIN B, Pathak JL, Gao H, Zhou Z, et al
    A pilot study examining periodontally healthy middle-aged humans and monkeys display different levels of alveolar bone resorption, gingival inflammatory infiltrate, and salivary microbiota profile.
    PLoS One. 2024;19:e0311282.
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  56. GATARAYIHA A, Ntaganira J, Brookes Z, Mutesa L, et al
    Periodontitis and pre-eclampsia among pregnant women in Rwanda: A case-control study.
    PLoS One. 2024;19:e0312103.
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  57. HAN M, Lee W, Ahn S, Kang MH, et al
    Synergistic effect of periodontitis and C-reactive protein levels on mortality: NHANES 2001-2004.
    PLoS One. 2024;19:e0309476.
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  58. GHAZAL T, Ahmed MA, Qazi FU, Haider MM, et al
    Mutational analysis of cytoplasmic domain of integrin subunit alpha-1 and its association with periapical wound healing after surgical endodontic treatment.
    PLoS One. 2024;19:e0303627.
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  59. YADALAM PK, Neelakandan A, Arunraj R, Anegundi RV, et al
    Exploring the interplay between Porphyromonas gingivalis KGP gingipain, herpes virus MicroRNA-6, and Icp4 transcript in periodontitis: Computational and clinical insights.
    PLoS One. 2024;19:e0312162.
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  60. FURLANETO F, Levi YLAS, Savio DSF, da Silveira ICF, et al
    Microbiological profile of patients with generalized gingivitis undergoing periodontal therapy and administration of Bifidobacterium animalis subsp. lactis HN019: A randomized clinical trial.
    PLoS One. 2024;19:e0310529.
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  61. TAKEUCHI R, Nomura T, Yaguchi M, Kuwahara N, et al
    Cyclosporine A causes gingival overgrowth via reduced G1 cell cycle arrest in gingival fibroblasts.
    PLoS One. 2024;19:e0309189.
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  62. WINCE C, Kassa CT, Insper J, Amzallag D, et al
    Antimicrobial photodynamic therapy effects mediated by methylene blue in surfactant medium as an adjuvant treatment of teeth with apical periodontitis and presence of fistula-Protocol for randomized, controlled, double-blind clinical trial.
    PLoS One. 2024;19:e0315169.
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  63. LI S, Liu J, Zhang R, Dong J, et al
    Association study of depressive symptoms and periodontitis in an obese population: Analysis based on NHANES data from 2009 to 2014.
    PLoS One. 2024;19:e0315754.
    >> Share

    January 2023
  64. OZIEGBE EO, Schepartz LA
    Parity, dental caries and implications for maternal depletion syndrome in northern Nigerian Hausa women.
    PLoS One. 2023;18:e0281653.
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  65. TRINDADE SC, Lopes MPP, Oliveira TTMC, Silva MJ, et al
    Single nucleotide variants in the IL33 and IL1RL1 (ST2) genes are associated with periodontitis and with Aggregatibacter actinomycetemcomitans in the dental plaque biofilm: A putative role in understanding the host immune response in periodontitis.
    PLoS One. 2023;18:e0283179.
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  66. ATIF S, Abdul Wahab N, Ghafoor S, Azlina A, et al
    Salivary aquaporin-3 as a screening biomarker for xerostomia in patients with periodontal disease and the effects of xerostomia on oral health-related quality of life.
    PLoS One. 2023;18:e0283995.
    >> Share

  67. DE ALMEIDA JM, de Araujo NJ, Matheus HR, de Abreu Furquim EM, et al
    Hand instrumentation provides improved tissue response over ultrasonic scaler and substantiates safe dental practice: An in vivo study in rats.
    PLoS One. 2023;18:e0284497.
    >> Share

  68. SANCHEZ-MEDRANO AG, Martinez-Martinez RE, Soria-Guerra R, Portales-Perez D, et al
    A systematic review of the protein composition of whole saliva in subjects with healthy periodontium compared with chronic periodontitis.
    PLoS One. 2023;18:e0286079.
    >> Share

  69. MICHALOWICZ BS, Anderson JP, Kottke TE, Dehmer SP, et al
    Periodontal treatment and subsequent clinical outcomes and medical care costs: A retrospective cohort study.
    PLoS One. 2023;18:e0290028.
    >> Share

  70. BUNNATEE P, Abdulsalam FI, Phoosuwan N
    Factors associated with oral health care behaviors of pregnant women in a northeastern province in Thailand: A hospital-based cross-sectional study.
    PLoS One. 2023;18:e0290334.
    >> Share

  71. GUO X, Li X, Liao C, Feng X, et al
    Periodontal disease and subsequent risk of cardiovascular outcome and all-cause mortality: A meta-analysis of prospective studies.
    PLoS One. 2023;18:e0290545.
    >> Share

  72. NGUYEN TPA, Gautam S, Mahato S, Jensen OC, et al
    Overview of oral health status and associated risk factors in maritime settings: An updated systematic review.
    PLoS One. 2023;18:e0293118.
    >> Share

  73. BAYANI M, Heidari M, Almasi-Hashiani A
    Periodontal disease and visfatin level: A systematic review and meta-analysis.
    PLoS One. 2023;18:e0293368.
    >> Share

  74. HALLON C, Barrionuevo-Leon C, Gallardo-Bastidas JC, Robles-Velasco K, et al
    Association between age people started working and missing teeth in an elderly population in Ecuador: Evidence from a cross-sectional study.
    PLoS One. 2023;18:e0293635.
    >> Share

  75. NAZARIO RMF, Frazao DR, Peinado BRR, Ferreira MKM, et al
    Is there an association between periodontal disease and root caries? A systematic review and meta-analysis.
    PLoS One. 2023;18:e0285955.
    >> Share

  76. WEESE JS, Battersby I, Morrison J, Spofford N, et al
    Antimicrobial use practices in canine and feline dental procedures performed in primary care veterinary practices in the United States.
    PLoS One. 2023;18:e0295070.
    >> Share


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