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Articles published in
Proc Natl Acad Sci U S A
    April 2024
  1. HIYOSHI H, Sakuma K, Asano S, Napier SC, et al
    Identification and removal of unexpected proliferative off-target cells emerging after iPSC-derived pancreatic islet cell implantation.
    Proc Natl Acad Sci U S A. 2024;121:e2320883121.
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  2. MURTHY D, Attri KS, Suresh V, Rajacharya GH, et al
    The MUC1-HIF-1alpha signaling axis regulates pancreatic cancer pathogenesis through polyamine metabolism remodeling.
    Proc Natl Acad Sci U S A. 2024;121:e2315509121.
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    August 2023
  3. DASGUPTA A, Gibbard DF, Schmitt RE, Arneson-Wissink PC, et al
    A TGF-beta/KLF10 signaling axis regulates atrophy-associated genes to induce muscle wasting in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2023;120:e2215095120.
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    May 2023
  4. CHANDA D, Thoudam T, Sinam IS, Lim CW, et al
    Upregulation of the ERRgamma-VDAC1 axis underlies the molecular pathogenesis of pancreatitis.
    Proc Natl Acad Sci U S A. 2023;120:e2219644120.
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    March 2023

  5. Correction for Taylor et al., Human pancreatic islet microRNAs implicated in diabetes and related traits by large-scale genetic analysis.
    Proc Natl Acad Sci U S A. 2023;120:e2302726120.
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  6. MELLO SS, Flowers BM, Mazur PK, Lee JJ, et al
    Multifaceted role for p53 in pancreatic cancer suppression.
    Proc Natl Acad Sci U S A. 2023;120:e2211937120.
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    February 2023
  7. TAYLOR HJ, Hung YH, Narisu N, Erdos MR, et al
    Human pancreatic islet microRNAs implicated in diabetes and related traits by large-scale genetic analysis.
    Proc Natl Acad Sci U S A. 2023;120:e2206797120.
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    January 2023

  8. Correction for Guo et al., Quantitative, in situ visualization of intracellular insulin vesicles in pancreatic beta cells.
    Proc Natl Acad Sci U S A. 2023;120:e2220560120.
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    November 2022
  9. RUBIN DE CELIS MF, Garcia-Martin R, Syed I, Lee J, et al
    PAHSAs reduce cellular senescence and protect pancreatic beta cells from metabolic stress through regulation of Mdm2/p53.
    Proc Natl Acad Sci U S A. 2022;119:e2206923119.
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    October 2022
  10. MICALIZZI DS, Che D, Nicholson BT, Edd JF, et al
    Targeting breast and pancreatic cancer metastasis using a dual-cadherin antibody.
    Proc Natl Acad Sci U S A. 2022;119:e2209563119.
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  11. SAAD MI, Weng T, Lundy J, Gearing LJ, et al
    Blockade of the protease ADAM17 ameliorates experimental pancreatitis.
    Proc Natl Acad Sci U S A. 2022;119:e2213744119.
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    August 2022
  12. GUO A, Zhang J, He B, Li A, et al
    Quantitative, in situ visualization of intracellular insulin vesicles in pancreatic beta cells.
    Proc Natl Acad Sci U S A. 2022;119:e2202695119.
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    May 2022

  13. Correction for Lebedeva et al., Strategy for reversing resistance to a single anticancer agent in human prostate and pancreatic carcinomas.
    Proc Natl Acad Sci U S A. 2022;119:e2204209119.
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  14. PRINCIPE DR, Aissa AF, Kumar S, Pham TND, et al
    Calcium channel blockers potentiate gemcitabine chemotherapy in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2022;119:e2200143119.
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  15. NAPOLEON JV, Sagar S, Kubica SP, Boghean L, et al
    Small-molecule IKKbeta activation modulator (IKAM) targets MAP3K1 and inhibits pancreatic tumor growth.
    Proc Natl Acad Sci U S A. 2022;119:e2115071119.
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    April 2022

  16. Correction for Morton et al., Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2022;119:e2204610119.
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  17. LARUE MM, Parker S, Puccini J, Cammer M, et al
    Metabolic reprogramming of tumor-associated macrophages by collagen turnover promotes fibrosis in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2022;119:e2119168119.
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    March 2022
  18. DOFFO J, Bamopoulos SA, Kose H, Orben F, et al
    NOXA expression drives synthetic lethality to RUNX1 inhibition in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2022;119.
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    January 2022
  19. PRINCIPE DR, Xiong R, Li Y, Pham TND, et al
    XP-524 is a dual-BET/EP300 inhibitor that represses oncogenic KRAS and potentiates immune checkpoint inhibition in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2022;119.
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    December 2021
  20. KATTAN WE, Liu J, Montufar-Solis D, Liang H, et al
    Components of the phosphatidylserine endoplasmic reticulum to plasma membrane transport mechanism as targets for KRAS inhibition in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2021;118.
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  21. LIN CW, Wang YJ, Lai TY, Hsu TL, et al
    Homogeneous antibody and CAR-T cells with improved effector functions targeting SSEA-4 glycan on pancreatic cancer.
    Proc Natl Acad Sci U S A. 2021;118.
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    August 2021
  22. WOLFE AL, Zhou Q, Toska E, Galeas J, et al
    UDP-glucose pyrophosphorylase 2, a regulator of glycogen synthesis and glycosylation, is critical for pancreatic cancer growth.
    Proc Natl Acad Sci U S A. 2021;118.
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    July 2021
  23. KING ME, Zhang J, Lin JQ, Garza KY, et al
    Rapid diagnosis and tumor margin assessment during pancreatic cancer surgery with the MasSpec Pen technology.
    Proc Natl Acad Sci U S A. 2021;118.
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    June 2021
  24. YANG Y, Wang H, He J, Shi W, et al
    A single-cell-resolution fate map of endoderm reveals demarcation of pancreatic progenitors by cell cycle.
    Proc Natl Acad Sci U S A. 2021;118.
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    May 2021
  25. CHENG DK, Oni TE, Thalappillil JS, Park Y, et al
    Oncogenic KRAS engages an RSK1/NF1 pathway to inhibit wild-type RAS signaling in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2021;118.
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    March 2021
  26. TSAI PY, Lee MS, Jadhav U, Naqvi I, et al
    Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1.
    Proc Natl Acad Sci U S A. 2021;118.
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    February 2021
  27. MOORE AM, Zhou L, Cui J, Li L, et al
    NAD(+) depletion by type I interferon signaling sensitizes pancreatic cancer cells to NAMPT inhibition.
    Proc Natl Acad Sci U S A. 2021;118.
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  28. MUKHOPADHYAY S, Biancur DE, Parker SJ, Yamamoto K, et al
    Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of SLC7A11.
    Proc Natl Acad Sci U S A. 2021;118.
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  29. Correction to Supporting Information for Qadir et al., Single-cell resolution analysis of the human pancreatic ductal progenitor cell niche.
    Proc Natl Acad Sci U S A. 2021;118.
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  30. MUCCIOLO G, Curcio C, Roux C, Li WY, et al
    IL17A critically shapes the transcriptional program of fibroblasts in pancreatic cancer and switches on their protumorigenic functions.
    Proc Natl Acad Sci U S A. 2021;118.
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    November 2020
  31. GRBOVIC-HUEZO O, Pitter KL, Lecomte N, Saglimbeni J, et al
    Unbiased in vivo preclinical evaluation of anticancer drugs identifies effective therapy for the treatment of pancreatic adenocarcinoma.
    Proc Natl Acad Sci U S A. 2020 Nov 16. pii: 1920240117.
    >> Share

    October 2020
  32. BIASCI D, Smoragiewicz M, Connell CM, Wang Z, et al
    CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune response.
    Proc Natl Acad Sci U S A. 2020 Oct 30. pii: 2013644117.
    >> Share

  33. WANG B, Lin H, Li X, Lu W, et al
    The adaptor protein APPL2 controls glucose-stimulated insulin secretion via F-actin remodeling in pancreatic beta-cells.
    Proc Natl Acad Sci U S A. 2020 Oct 29. pii: 2016997117.
    >> Share

  34. WEI X, Yang J, Adair SJ, Ozturk H, et al
    Targeted CRISPR screening identifies PRMT5 as synthetic lethality combinatorial target with gemcitabine in pancreatic cancer cells.
    Proc Natl Acad Sci U S A. 2020 Oct 23. pii: 2009899117.
    >> Share


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