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Articles published in
Diabetes
    September 2025
  1. LEON S, Benoit J, Clark S, Zizzari P, et al
    GLP-1-Mediated Targeting of Inflammation Corrects Obesogenic Memory in Male Mice.
    Diabetes. 2025;74:1525-1534.
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    August 2025
  2. CARTWRIGHT BR, Scherer PE
    Adipose Tissue as a Target for Precision Medicine Approaches in Childhood Obesity.
    Diabetes. 2025 Aug 12:dbi240044. doi: 10.2337/dbi24-0044.
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  3. DE SOUSA E, Sparks L, Townsend K
    Incretin Receptors in the Peripheral Nervous System: Implications for Obesity Treatment and Peripheral Neuropathy.
    Diabetes. 2025;74:1313-1319.
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  4. CAMPBELL JE, Drucker DJ
    Therapeutic Targeting of the GIP Receptor-Revisiting the Controversies.
    Diabetes. 2025;74:1320-1325.
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    July 2025
  5. SHANTARAM D, Rima XY, Bradley D, Liu JZ, et al
    The GLP-1 Receptor Agonist Dulaglutide Attenuates Hepatic Steatosis in Obesity via a Weight-Independent Mechanism.
    Diabetes. 2025 Jul 15:db240861. doi: 10.2337/db24-0861.
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  6. CHEN AS, Batsis JA
    Treating Sarcopenic Obesity in the Era of Incretin Therapies: Perspectives and Challenges.
    Diabetes. 2025 Jul 11:dbi250004. doi: 10.2337/dbi25-0004.
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  7. HARPER ME, Dent RRM, McPherson R
    High-Quality Weight Loss in Obesity: Importance of Skeletal Muscle.
    Diabetes. 2025 Jul 8:dbi250003. doi: 10.2337/dbi25-0003.
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  8. WU X, Peng J, Jin C
    Deciphering Macrophage-Fibroblast Cross Talk in Obesity-Induced Adipose Tissue Fibrosis: Insights From Single-Cell and Spatial Transcriptomics.
    Diabetes. 2025;74:e12.
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  9. WANG P, Zhu J, Yang L, Wang Y, et al
    BAP1 Suppresses White Adipose Tissue Browning and Thermogenesis Through Deubiquitinating KDM1B.
    Diabetes. 2025;74:1153-1167.
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    June 2025
  10. SAMMS RJ, Sloop KW
    A Contemporary Rationale for Agonism of the GIP Receptor in the Treatment of Obesity.
    Diabetes. 2025 Jun 16:dbi240026. doi: 10.2337/dbi24-0026.
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  11. ROSENKILDE MM, George JT, Veniant MM, Holst JJ, et al
    GIP Receptor Antagonists in the Pharmacotherapy of Obesity: Physiologic, Genetic, and Clinical Rationale.
    Diabetes. 2025 Jun 16:dbi240027. doi: 10.2337/dbi24-0027.
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    May 2025
  12. ALBIERO M, Migliozzi L, Boscaro C, Rodella A, et al
    Padi4-Dependent NETosis Enables Diet-Induced Gut Hyperpermeability, Translating Dysbiosis Into Systemic Inflammation and Dysmetabolism.
    Diabetes. 2025;74:705-719.
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    April 2025
  13. ODOEMELAM CS, Naz A, Thanaj M, Sorokin EP, et al
    Identifying four obesity axes through integrative multi-omics and imaging analysis.
    Diabetes. 2025 Apr 24:db241103. doi: 10.2337/db24-1103.
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    March 2025
  14. KOHDA H, Tanaka M, Shichino S, Arakawa S, et al
    Novel cell-to-cell communications between macrophages and fibroblasts regulate obesity-induced adipose tissue fibrosis.
    Diabetes. 2025 Mar 10:db240762. doi: 10.2337/db24-0762.
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  15. CIFARELLI V, Smith GI, Gonzalez-Nieves S, Samovski D, et al
    Adipose Tissue Biology and Effect of Weight Loss in Women With Lipedema.
    Diabetes. 2025;74:308-319.
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  16. QIU C, Lu Y, Wu S, Guo W, et al
    Blocking Adipocyte YY1 Decouples Thermogenesis From Beneficial Metabolism by Promoting Spermidine Production.
    Diabetes. 2025;74:295-307.
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    February 2025
  17. XIE QY, Granato A, Wong A, Yau C, et al
    Metabolic dysfunction associated with alterations in gut microbiota in adolescents with obesity.
    Diabetes. 2025 Feb 21:db240866. doi: 10.2337/db24-0866.
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    January 2025
  18. D'ALESSIO DA, Kahn SE
    The Development of Glucagon-Like Peptide 1 as a Therapeutic: The Triumph of the Lasker Award for Obesity Is a Victory for Diabetes Research.
    Diabetes. 2025;74:1-3.
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    December 2024
  19. LIM CGY, Ozkan B, Liang Y, Chen J, et al
    Plasma proteomic signatures of adiposity are associated with cardiovascular risk factors and type 2 diabetes risk in a multi-ethnic Asian population.
    Diabetes. 2024 Dec 2:db240184. doi: 10.2337/db24-0184.
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  20. SCHLEH MW, Ameka MK, Rodriguez AS, Hasty AH, et al
    Deficiency of the Hemoglobin-Haptoglobin Receptor, CD163, Worsens Insulin Sensitivity in Obese Male Mice.
    Diabetes. 2024;73:1990-2002.
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  21. LOH NY, Rosoff DB, Richmond R, Noordam R, et al
    Bidirectional Mendelian Randomization Highlights Causal Relationships Between Circulating INHBC and Multiple Cardiometabolic Diseases and Traits.
    Diabetes. 2024;73:2084-2094.
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  22. MIYAMORI H, Yokokawa T, Miyakita M, Ozaki K, et al
    CRTC1 in Mc4r-Expressing Cells Is Required for Peripheral Metabolism and Systemic Energy Homeostasis.
    Diabetes. 2024;73:1976-1989.
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    November 2024
  23. HARNOIS-LEBLANC S, Hivert MF
    Stopping the intergenerational risk of diabetes - from mechanisms to interventions.
    Diabetes. 2024 Nov 18:dbi240014. doi: 10.2337/dbi24-0014.
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  24. ZHANG Y, Qian B, Yang Y, Niu F, et al
    Visceral Adipocyte-Derived Extracellular Vesicle miR-27a-5p Elicits Glucose Intolerance by Inhibiting Pancreatic beta-Cell Insulin Secretion.
    Diabetes. 2024;73:1832-1847.
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  25. EID SA, Elzinga SE, Kim B, Rumora AE, et al
    High-Intensity Interval Training, Caloric Restriction, or Their Combination Have Beneficial Effects on Metabolically Acquired Peripheral Neuropathy.
    Diabetes. 2024;73:1895-1907.
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    October 2024
  26. PAGE KA
    Neurodevelopmental Pathways to Obesity and Type 2 Diabetes: Insights From Prenatal Exposure to Maternal Obesity and Gestational Diabetes Mellitus: A Report on Research Supported by Pathway to Stop Diabetes.
    Diabetes. 2024 Oct 21:dbi240012. doi: 10.2337/dbi24-0012.
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  27. FLAK JN
    Functionally Separate Populations of Ventromedial Hypothalamic Neurons in Obesity and Diabetes.
    Diabetes. 2024 Oct 17:dbi240011. doi: 10.2337/dbi24-0011.
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  28. TOWNSEND KL
    One Nervous System: Critical Links Between Central and Peripheral Nervous System Health and Implications for Obesity and Diabetes.
    Diabetes. 2024 Oct 14:dbi240004. doi: 10.2337/dbi24-0004.
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    September 2024
  29. PARK CB, Lee CH, Cho KW, Shin S, et al
    Extracellular cleavage of microglia-derived progranulin promotes diet-induced obesity.
    Diabetes. 2024 Sep 20:db240097. doi: 10.2337/db24-0097.
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  30. PETERSEN MC, Yoshino M, Smith GI, Gaspar RC, et al
    Effect of Weight Loss on Skeletal Muscle Bioactive Lipids in People with Obesity and Type 2 Diabetes.
    Diabetes. 2024 Sep 12:db240083. doi: 10.2337/db24-0083.
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  31. USSHER JR, Aasum E
    The Relationship Between Cardiac Energy Metabolism and Cardiac Function in Obesity and Type 2 Diabetes: Revisiting a 2003 Diabetes Classic by Aasum et al.
    Diabetes. 2024;73:1373-1376.
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    August 2024
  32. CHEN X, Ruiz-Velasco A, Zou Z, Hille SS, et al
    PAK3 Exacerbates Cardiac Lipotoxicity via SREBP1c in Obesity Cardiomyopathy.
    Diabetes. 2024 Aug 13:db240240. doi: 10.2337/db24-0240.
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    July 2024
  33. LUONG TV, Pedersen MGB, Abild CB, Lauritsen KM, et al
    A three-week ketogenic diet increases skeletal muscle insulin sensitivity in individuals with obesity - a randomized, controlled crossover trial.
    Diabetes. 2024 Jul 25:db240162. doi: 10.2337/db24-0162.
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  34. KJELDSEN SAS, Richter MM, Jensen NJ, Nilsson MSD, et al
    Glucagon resistance in individuals with obesity and hepatic steatosis can be measured using the GLUSENTIC test and index.
    Diabetes. 2024 Jul 8:db230858. doi: 10.2337/db23-0858.
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  35. DELLA PEPA G, Patricio BG, Carli F, Sabatini S, et al
    GLP-1 receptor agonist treatment improved fasting and postprandial lipidomic profile independently of diabetes and weight loss.
    Diabetes. 2024 Jul 8:db230972. doi: 10.2337/db23-0972.
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  36. PARK S, Cha HN, Shin MG, Park S, et al
    Inhibitory Regulation of FOXO1 in PPARdelta Expression Drives Mitochondrial Dysfunction and Insulin Resistance.
    Diabetes. 2024;73:1084-1098.
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    June 2024
  37. MITTENDORFER B, Johnson JD, Solinas G, Jansson PA, et al
    Insulin Hypersecretion as Promoter of Body Fat Gain and Hyperglycemia.
    Diabetes. 2024;73:837-843.
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  38. PESCHARD S, Raverdy V, Bauvin P, Goutchtat R, et al
    Genetic Evidence of Causal Relation Between Intestinal Glucose Absorption and Early Postprandial Glucose Response: A Mendelian Randomization Study.
    Diabetes. 2024;73:983-992.
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    May 2024
  39. FISHER C, Johnson K, Moore M, Sadrati A, et al
    Loss of ATP-sensitive potassium channel expression and function in the nervous system decreases opioid sensitivity in high-fat-diet-fed mouse model of diet-induced obesity.
    Diabetes. 2024 May 22:db231030. doi: 10.2337/db23-1030.
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  40. DIAMOND C, Pansini M, Hamid A, Eichert N, et al
    Quantitative imaging reveals steatosis and fibro-inflammation in multiple organs in people with type 2 diabetes: a real-world study.
    Diabetes. 2024 May 14:db230926. doi: 10.2337/db23-0926.
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  41. SHEN KC, Collins KH, Ferey JLA, Fappi A, et al
    Excess Intramyocellular Lipid Does Not Affect Muscle Fiber Biophysical Properties in Mice or People with Metabolically Abnormal Obesity.
    Diabetes. 2024 May 3:db230991. doi: 10.2337/db23-0991.
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  42. CHOUCAIR I, Mallela DP, Hilser JR, Hartiala JA, et al
    Comprehensive clinical and genetic analyses of circulating bile acids and their associations with diabetes and its indices.
    Diabetes. 2024 May 3:db230676. doi: 10.2337/db23-0676.
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  43. GUPTA OT, Gupta RK
    The Expanding Problem of Regional Adiposity: Revisiting a 1985 Diabetes Classic by Ohlson et al.
    Diabetes. 2024;73:649-652.
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  44. LEE SH, Suh JH, Heo MJ, Choi JM, et al
    The Hepatokine Orosomucoid 2 Mediates Beneficial Metabolic Effects of Bile Acids.
    Diabetes. 2024;73:701-712.
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    April 2024
  45. SMEEHUIJZEN L, Gijbels A, Nugteren-Boogaard JP, Vrieling F, et al
    Immunometabolic Signatures of Circulating Monocytes in Humans with Obesity and Insulin Resistance.
    Diabetes. 2024 Apr 24:db230970. doi: 10.2337/db23-0970.
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  46. LIU J, Aylor KW, Liu Z
    Erratum. Liraglutide and Exercise Synergistically Attenuate Vascular Inflammation and Enhance Metabolic Insulin Action in Early Diet-Induced Obesity. Diabetes 2023;72:918-931.
    Diabetes. 2024 Apr 23:db24er07a. doi: 10.2337.
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  47. PURNELL JQ
    Metabolic-Bariatric Surgery for Type 2 Diabetes: Time(ing) for a Change.
    Diabetes. 2024;73:542-544.
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    March 2024
  48. ABRAHAM A, Cule M, Thanaj M, Basty N, et al
    Genetic evidence for distinct biological mechanisms that link adiposity to type 2 diabetes: towards precision medicine.
    Diabetes. 2024 Mar 26:db231005. doi: 10.2337/db23-1005.
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  49. FAN Y, Chow E, Lim CKP, Hou Y, et al
    Comparison of beta-cell function and insulin sensitivity between normal-weight and obese Chinese with young-onset type 2 diabetes.
    Diabetes. 2024 Mar 20:db230966. doi: 10.2337/db23-0966.
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  50. RAMSHANKAR G, Perry RJ
    A New Mitochondrial Uncoupler Improves Metabolic Homeostasis in Mice.
    Diabetes. 2024;73:357-358.
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  51. RIERA CE
    Wiring the Brain for Wellness: Sensory Integration in Feeding and Thermogenesis: A Report on Research Supported by Pathway to Stop Diabetes.
    Diabetes. 2024;73:338-347.
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    February 2024
  52. LI X, Su Y, Xu Y, Hu T, et al
    Adipocyte-specific Hnrnpa1 knockout aggravates obesity-induced metabolic dysfunction via upregulating of CCL2.
    Diabetes. 2024 Feb 6:db230609. doi: 10.2337/db23-0609.
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  53. GILANI A, Stoll L, Homan EA, Lo JC, et al
    Adipose Signals Regulating Distal Organ Health and Disease.
    Diabetes. 2024;73:169-177.
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  54. VALI A, Dalle H, Loubaresse A, Gilleron J, et al
    Adipocyte Glucocorticoid Receptor Activation With High Glucocorticoid Doses Impairs Healthy Adipose Tissue Expansion by Repressing Angiogenesis.
    Diabetes. 2024;73:211-224.
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  55. HUANG J, Zhang Y, Zhou X, Song J, et al
    Foxj3 Regulates Thermogenesis of Brown and Beige Fat Via Induction of PGC-1alpha.
    Diabetes. 2024;73:178-196.
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  56. ZHAO S, Li N, Xiong W, Li G, et al
    Leptin Reduction as a Required Component for Weight Loss.
    Diabetes. 2024;73:197-210.
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  57. FURBER EC, Hyatt K, Collins K, Yu X, et al
    GIPR Agonism Enhances TZD-Induced Insulin Sensitivity in Obese IR Mice.
    Diabetes. 2024;73:292-305.
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    January 2024
  58. BACHA F, El-Ayash H, Mohamad M, Sharma S, et al
    Distinct Amino Acid Profile Characterizes Youth with or at risk for Type 2 Diabetes.
    Diabetes. 2024 Jan 12:db230375. doi: 10.2337/db23-0375.
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  59. PURVIS GSD, Collino M, van Dam AD, Einaudi G, et al
    OxPhos in adipose tissue macrophages regulated by BTK enhances their M2-like phenotype and confers a systemic immunometabolic benefit in obesity.
    Diabetes. 2024 Jan 8:db220275. doi: 10.2337/db22-0275.
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  60. HUANG M, Prasad RB, Coral DE, Hjort L, et al
    Human Genetic Variation at rs10071329 Correlates with Adiposity-related Traits, Modulates PPARGC1B Expression, and Alters Brown Adipocyte Function.
    Diabetes. 2024 Jan 8:db230531. doi: 10.2337/db23-0531.
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  61. WANG D, Jabile MJT, Lu J, Townsend LK, et al
    Fatty Acids Increase GDF15 and Reduce Food Intake Through a GFRAL Signaling Axis.
    Diabetes. 2024;73:51-56.
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    December 2023
  62. LUK CT, Chan CK, Chiu F, Shi SY, et al
    Dual Role of Caspase 8 in Adipocyte Apoptosis and Metabolic Inflammation.
    Diabetes. 2023;72:1751-1765.
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    November 2023
  63. KELLER MP, O'Connor C, Bitzer M, Schueler KL, et al
    Genetic analysis of obesity-induced diabetic nephropathy in BTBR mice.
    Diabetes. 2023 Nov 7:db230444. doi: 10.2337/db23-0444.
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  64. BROTMAN SM, Oravilahti A, Rosen JD, Alvarez M, et al
    Cell-Type Composition Affects Adipose Gene Expression Associations With Cardiometabolic Traits.
    Diabetes. 2023;72:1707-1718.
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  65. HUANG Y, Hertzel AV, Fish SR, Halley CL, et al
    TP53/p53 Facilitates Stress-Induced Exosome and Protein Secretion by Adipocytes.
    Diabetes. 2023;72:1560-1573.
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    October 2023
  66. WRIGHT JJ, Eskaros A, Windon A, Bottino R, et al
    Exocrine pancreas in type 1 and type 2 diabetes: different patterns of fibrosis, metaplasia, angiopathy, and adiposity.
    Diabetes. 2023 Oct 26:db230009. doi: 10.2337/db23-0009.
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  67. MASHAYEKHI M, Nian H, Mayfield D, Devin JK, et al
    Weight Loss-Independent Effect of Liraglutide on Insulin Sensitivity in Individuals with Obesity and Pre-Diabetes.
    Diabetes. 2023 Oct 24:db230356. doi: 10.2337/db23-0356.
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  68. BERETTA M, Dai Y, Olzomer EM, Vancuylenburg CS, et al
    Liver-selective imidazolopyrazine mitochondrial uncoupler SHD865 reverses adiposity and glucose intolerance in mice.
    Diabetes. 2023 Oct 23:db230233. doi: 10.2337/db23-0233.
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  69. TRICO D, Chiriaco M, Nouws J, Vash-Margita A, et al
    Alterations in adipose tissue distribution, cell morphology and function mark primary insulin hypersecretion in youths with obesity.
    Diabetes. 2023 Oct 23:db230450. doi: 10.2337/db23-0450.
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  70. BONET ML, Ribot J, Pico C
    Decoding the Mechanisms Behind Early Weaning-Driven Obesity and the Leucine "Solution".
    Diabetes. 2023;72:1347-1349.
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    September 2023
  71. FELIX JF, Grant SFA
    Keeping It in the Family: Consanguinity Reveals P4HTM as a Novel Syndromic Obesity Gene.
    Diabetes. 2023;72:1184-1186.
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  72. PAN Q, Ai W, Chen Y, Kim DM, et al
    Reciprocal Regulation of Hepatic TGF-beta1 and Foxo1 Controls Gluconeogenesis and Energy Expenditure.
    Diabetes. 2023;72:1193-1206.
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    August 2023
  73. DENG Y, Liu X, Xie M, Zhao R, et al
    Obesity enables NLRP3 activation and induces myocardial fibrosis via hyperacetylation of HADHa.
    Diabetes. 2023 Aug 25:db230264. doi: 10.2337/db23-0264.
    >> Share

  74. ZHONG Y, Wang Y, Li X, Qin H, et al
    PRMT4 Facilitates White Adipose Tissue Browning and Thermogenesis by Methylating PPARgamma.
    Diabetes. 2023;72:1095-1111.
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    July 2023
  75. CHRISTIANSEN MR, Kilpelainen TO, Mccaffery JM
    Abdominal obesity genetic variants predict waist circumference regain after weight loss.
    Diabetes. 2023 Jul 26:db230131. doi: 10.2337/db23-0131.
    >> Share

  76. ZARINI S, Zemski Berry KA, Kahn DE, Garfield A, et al
    Deoxysphingolipids: Atypical Skeletal Muscle Lipids Related to Insulin Resistance in Humans That Decrease Insulin Sensitivity In Vitro.
    Diabetes. 2023;72:884-897.
    >> Share

  77. PETRICK HL, Ogilvie LM, Brunetta HS, Robinson A, et al
    Dietary Nitrate and Corresponding Gut Microbiota Prevent Cardiac Dysfunction in Obese Mice.
    Diabetes. 2023;72:844-856.
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    June 2023
  78. CHEN YC, Taylor AJ, Fulcher JM, Swensen AC, et al
    Deletion of carboxypeptidase E in beta cells disrupts proinsulin processing but does not lead to spontaneous development of diabetes in mice.
    Diabetes. 2023 Jun 26:db220945. doi: 10.2337/db22-0945.
    >> Share

    May 2023
  79. ZENG L, Herdman DS, Lee SM, Tao A, et al
    Loss of cAMP signaling in CD11c immune cells protects against diet-induced obesity.
    Diabetes. 2023 May 31:db221035. doi: 10.2337/db22-1035.
    >> Share

  80. HUANG X, Zhao Y, Liu T, Wu D, et al
    beta-cell function and insulin dynamics in obese patients with and without diabetes after sleeve gastrectomy.
    Diabetes. 2023 May 31:db221048. doi: 10.2337/db22-1048.
    >> Share

  81. XIE R, Yan S, Zhou X, Gao Y, et al
    Activation of METTL3 promotes white adipose tissue beiging and combats obesity.
    Diabetes. 2023 May 24:db220775. doi: 10.2337/db22-0775.
    >> Share

  82. NGUYEN A, Khafagy R, Gao Y, Meerasa A, et al
    Erratum. Association Between Obesity and Chronic Kidney Disease: Multivariable Mendelian Randomization Analysis and Observational Data From a Bariatric Surgery Cohort. Diabetes 2023;72:496-510.
    Diabetes. 2023 May 18:db23er08a. doi: 10.2337.
    >> Share

  83. SUN Y, Sun B, Han X, Shan A, et al
    Leucine supplementation ameliorates early life "programming" of obesity in rats.
    Diabetes. 2023 May 17:db220862. doi: 10.2337/db22-0862.
    >> Share

  84. REYNOLDS GP
    Comment on Tabatabaei Dakhili et al. The Antipsychotic Dopamine 2 Receptor Antagonist Diphenylbutylpiperidines Improve Glycemia in Experimental Obesity by Inhibiting Succinyl-CoA:3-Ketoacid CoA Transferase. Diabetes 2023;72:126-134.
    Diabetes. 2023;72:e5.
    >> Share

    April 2023
  85. SAEED S, Ning L, Badreddine A, Mirza MU, et al
    Biallelic mutations in P4HTM cause syndromic obesity.
    Diabetes. 2023 Apr 21:db221017. doi: 10.2337/db22-1017.
    >> Share

  86. LIU J, Aylor KW, Liu Z
    Liraglutide and Exercise Synergistically Attenuate Vascular Inflammation and Enhance Metabolic Insulin Action in Early Diet-induced Obesity.
    Diabetes. 2023 Apr 19:db220745. doi: 10.2337/db22-0745.
    >> Share

  87. LIU C, Meng M, Xu B, Xu Y, et al
    Fibroblast Growth Factor 6 Promotes Adipocyte Progenitor Cell Proliferation for Adipose Tissue Homeostasis.
    Diabetes. 2023;72:467-482.
    >> Share

    March 2023
  88. VIDMAR AP, Durazo-Arvizu R, Weigensberg MJ, Alderete TL, et al
    Rapid Decline in Beta-Cell Function and Increasing Adiposity is Associated with Conversion to Type 2 Diabetes in at Risk Latino Youth.
    Diabetes. 2023 Mar 27:db221034. doi: 10.2337/db22-1034.
    >> Share

  89. LUAN D, Dadpey B, Zaid J, Bridge-Comer PE, et al
    Adipocyte-Secreted IL-6 Sensitizes Macrophages to IL-4 Signaling.
    Diabetes. 2023;72:367-374.
    >> Share

  90. ANDERSSON DP, Kerr AG, Dahlman I, Ryden M, et al
    Relationship Between a Sedentary Lifestyle and Adipose Insulin Resistance.
    Diabetes. 2023;72:316-325.
    >> Share

    January 2023
  91. CHEN ZZ, Gao Y, Keyes MJ, Deng S, et al
    Protein Markers of Diabetes Discovered in an African American Cohort.
    Diabetes. 2023 Jan 11:db220710. doi: 10.2337/db22-0710.
    >> Share


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