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Articles published in
J Clin Invest
    March 2025
  1. WEI J, Moon J, Yasumizu Y, Zhang L, et al
    Transcriptomic profiling after B-cell depletion reveals central and peripheral immune cell changes in multiple sclerosis.
    J Clin Invest. 2025 Mar 11:e182790. doi: 10.1172/JCI182790.
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  2. DICILLO EB, Kountikov E, Zhu M, Lanker S, et al
    Patterns of autoantibody expression in multiple sclerosis identified through development of an autoantigen discovery technology.
    J Clin Invest. 2025;135:e171948.
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    January 2025
  3. CANTONI C, Smirnov RA, Firulyova M, Andhey PS, et al
    A single-cell compendium of human cerebrospinal fluid identifies disease-associated immune cell populations.
    J Clin Invest. 2025;135:e177793.
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    December 2024
  4. VERMA SC, Enee E, Manasse K, Rebhi F, et al
    Cathelicidin antimicrobial peptide expression in neutrophils and neurons antagonistically modulates neuroinflammation.
    J Clin Invest. 2024;135:e184502.
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    November 2024
  5. VIETZEN H, Kuhner LM, Berger SM, Furlano PL, et al
    Accumulation of Epstein-Barr virus-induced cross-reactive immune responses is associated with multiple sclerosis.
    J Clin Invest. 2024;134:e184481.
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    September 2024
  6. FONDELLI F, Willemyns J, Domenech-Garcia R, Mansilla MJ, et al
    Targeting aryl hydrocarbon receptor functionally restores tolerogenic dendritic cells derived from patients with multiple sclerosis.
    J Clin Invest. 2024 Sep 17:e178949. doi: 10.1172/JCI178949.
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    June 2024
  7. WOO MS, Bal LC, Winschel I, Manca E, et al
    The NR4A2/VGF pathway fuels inflammation-induced neurodegeneration via promoting neuronal glycolysis.
    J Clin Invest. 2024;134:e177692.
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    May 2024
  8. GHORBANI S, Li C, Lozinski BM, Moezzi D, et al
    Fibulin-2 is an extracellular matrix inhibitor of oligodendrocytes relevant to multiple sclerosis.
    J Clin Invest. 2024 May 14:e176910. doi: 10.1172/JCI176910.
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    December 2023
  9. JOHANN L, Soldati S, Muller K, Lampe J, et al
    A20 regulates lymphocyte adhesion in murine neuroinflammation by restricting endothelial ICOSL expression in the CNS.
    J Clin Invest. 2023;133:e168314.
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    September 2023
  10. CLARKSON BD, Grund EM, Standiford MM, Mirchia K, et al
    CD8+ T cells recognizing a neuron-restricted antigen injure axons in a model of multiple sclerosis.
    J Clin Invest. 2023 Sep 7:e162788. doi: 10.1172/JCI162788.
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    August 2023
  11. OWENS GP, Fellin TJ, Matschulat A, Salas V, et al
    Pathogenic myelin specific antibodies in multiple sclerosis target conformational proteolipid protein 1 anchored membrane domains.
    J Clin Invest. 2023 Aug 10:e162731. doi: 10.1172/JCI162731.
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    May 2023
  12. KERKERING J, Muinjonov B, Rosiewicz KS, Diecke S, et al
    iPSC-derived reactive astrocytes from patients with multiple-sclerosis protect cocultured neurons in inflammatory conditions.
    J Clin Invest. 2023 May 23:e164637. doi: 10.1172/JCI164637.
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  13. REDER AT
    Clostridium epsilon toxin is excessive in multiple sclerosis and provokes multifocal lesions in mouse models.
    J Clin Invest. 2023;133:e169643.
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  14. MA Y, Sannino D, Linden JR, Haigh S, et al
    Epsilon toxin-producing Clostridium perfringens colonize the multiple sclerosis gut microbiome overcoming CNS immune privilege.
    J Clin Invest. 2023;133:e163239.
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    April 2023
  15. ANTEL JP, Kennedy TE, Kuhlmann T
    Seeking neuroprotection in multiple sclerosis: an ongoing challenge.
    J Clin Invest. 2023;133:e168595.
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  16. KAPELL H, Fazio L, Dyckow J, Schwarz S, et al
    Neuron-oligodendrocyte potassium shuttling at nodes of Ranvier protects against inflammatory demyelination.
    J Clin Invest. 2023;133:e164223.
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