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Multiple Sclerosis

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Articles published in
Brain
    June 2021
  1. BITTNER S, Oh J, Havrdova EK, Tintore M, et al
    The potential of serum neurofilament as biomarker for multiple sclerosis.
    Brain. 2021 Jun 28. pii: 6310737. doi: 10.1093.
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    May 2021
  2. GRANZIERA C, Wuerfel J, Barkhof F, Calabrese M, et al
    Quantitative magnetic resonance imaging towards clinical application in multiple sclerosis.
    Brain. 2021 May 10. pii: 6273092. doi: 10.1093.
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    April 2021
  3. GHORBANI S, Yong VW
    The extracellular matrix as modifier of neuroinflammation and remyelination in multiple sclerosis.
    Brain. 2021 Apr 23. pii: 6247173. doi: 10.1093.
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  4. PARDINI M, Brown JWL, Magliozzi R, Reynolds R, et al
    Surface-in pathology in multiple sclerosis: a new view on pathogenesis?
    Brain. 2021 Apr 20. pii: 6238675. doi: 10.1093.
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  5. PISA M, Croese T, Dalla Costa G, Guerrieri S, et al
    Subclinical anterior optic pathway involvement in early multiple sclerosis and clinically isolated syndromes.
    Brain. 2021 Apr 8. pii: 6215108. doi: 10.1093.
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    March 2021
  6. ONTANEDA D, Raza PC, Mahajan KR, Arnold DL, et al
    Deep grey matter injury in multiple sclerosis: A NAIMS consensus statement.
    Brain. 2021 Mar 23. pii: 6184142. doi: 10.1093.
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  7. SABEL CE, Pearson JF, Mason DF, Willoughby E, et al
    The latitude gradient for multiple sclerosis prevalence is established in the early lifecourse.
    Brain. 2021 Mar 11. pii: 6168130. doi: 10.1093.
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  8. RAHMANZADEH R, Lu PJ, Barakovic M, Weigel M, et al
    Myelin and axon pathology in multiple sclerosis assessed by myelin water and multi-shell diffusion imaging.
    Brain. 2021 Mar 9. pii: 6164965. doi: 10.1093.
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  9. XU Y, Smith KA, Hiyoshi A, Piehl F, et al
    Hospital-diagnosed infections before age 20 and risk of a subsequent multiple sclerosis diagnosis.
    Brain. 2021 Mar 9. pii: 6164964. doi: 10.1093.
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    February 2021
  10. KILPATRICK TJ, Binder MD
    Neuregulin therapy for multiple sclerosis: an each-way bet?
    Brain. 2021;144:6-8.
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    January 2021
  11. DAL-BIANCO A, Grabner G, Kronnerwetter C, Weber M, et al
    Long-term evolution of multiple sclerosis iron rim lesions in 7 T MRI.
    Brain. 2021 Jan 23. pii: 6114694. doi: 10.1093.
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  12. Corrigendum to: Quantitative spinal cord MRI in MOG-antibody disease, neuromyelitis optica and multiple sclerosis.
    Brain. 2021 Jan 11. pii: 6082765. doi: 10.1093.
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    December 2020
  13. KIM K, Probstel AK, Baumann R, Dyckow J, et al
    Cell type-specific transcriptomics identifies neddylation as a novel therapeutic target in multiple sclerosis.
    Brain. 2020 Dec 29. pii: 6055080. doi: 10.1093.
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  14. HALDER SK, Milner R
    Hypoxia in multiple sclerosis; is it the chicken or the egg?
    Brain. 2020 Dec 22. pii: 6044083. doi: 10.1093.
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  15. KATARIA H, Hart CG, Alizadeh A, Cossoy M, et al
    Neuregulin-1 beta 1 is implicated in pathogenesis of multiple sclerosis.
    Brain. 2020 Dec 13. pii: 6032483. doi: 10.1093.
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  16. HOHLFELD R, Beltran E, Gerdes LA, Dornmair K, et al
    Tissue-resident CD8+ memory T cells in multiple sclerosis.
    Brain. 2020 Dec 13. pii: 6032479. doi: 10.1093.
    >> Share

  17. SMOLDERS J, Fransen NL, Huitinga I, Hamann J, et al
    Reply: Tissue-resident CD8+ memory T cells in multiple sclerosis.
    Brain. 2020 Dec 13. pii: 6032480. doi: 10.1093.
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    November 2020
  18. PETROU P, Kassis I, Levin N, Paul F, et al
    Beneficial effects of autologous mesenchymal stem cell transplantation in active progressive multiple sclerosis.
    Brain. 2020 Nov 30. pii: 6012789. doi: 10.1093.
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  19. PETZOLD A, Chua SYL, Khawaja AP, Keane PA, et al
    Retinal asymmetry in multiple sclerosis.
    Brain. 2020 Nov 30. pii: 6012795. doi: 10.1093.
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  20. SCHIAVI S, Petracca M, Sun P, Fleysher L, et al
    Non-invasive quantification of inflammation, axonal and myelin injury in multiple sclerosis.
    Brain. 2020 Nov 30. pii: 5999115. doi: 10.1093.
    >> Share

  21. DE MEO E, Storelli L, Moiola L, Ghezzi A, et al
    In vivo gradients of thalamic damage in paediatric multiple sclerosis: a window into pathology.
    Brain. 2020 Nov 21. pii: 5998271. doi: 10.1093.
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  22. MARIANO R, Messina S, Roca-Fernandez A, Leite MI, et al
    Quantitative spinal cord MRI in MOG-antibody disease, neuromyelitis optica and multiple sclerosis.
    Brain. 2020 Nov 18. pii: 5989776. doi: 10.1093.
    >> Share

  23. ELLENBERGER D, Flachenecker P, Fneish F, Frahm N, et al
    Aggressive multiple sclerosis - a matter of measurement and timing.
    Brain. 2020 Nov 11. pii: 5974108. doi: 10.1093.
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  24. KALINCIK T, Malpas CB
    Reply: Aggressive multiple sclerosis - a matter of measurement and timing.
    Brain. 2020 Nov 11. pii: 5974107. doi: 10.1093.
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    October 2020
  25. SUCKSDORFF M, Matilainen M, Tuisku J, Polvinen E, et al
    Brain TSPO-PET predicts later disease progression independent of relapses in multiple sclerosis.
    Brain. 2020 Oct 2. pii: 5917253. doi: 10.1093.
    >> Share

  26. GAUDIOSO C, Naismith RT
    Optimizing treatment strategies in paediatric, adult and late-onset multiple sclerosis.
    Brain. 2020;143:2866-2868.
    >> Share

    September 2020
  27. AMATO MP, Fonderico M, Portaccio E, Pasto L, et al
    Disease-modifying drugs can reduce disability progression in relapsing multiple sclerosis.
    Brain. 2020 Sep 16. pii: 5906150. doi: 10.1093.
    >> Share

  28. OUELLETTE R, Treaba CA, Granberg T, Herranz E, et al
    7 T imaging reveals a gradient in spinal cord lesion distribution in multiple sclerosis.
    Brain. 2020 Sep 16. pii: 5906152. doi: 10.1093.
    >> Share

  29. GERALDES R, Esiri MM, Perera R, Yee SA, et al
    Vascular disease and multiple sclerosis: a post-mortem study exploring their relationships.
    Brain. 2020 Sep 2. pii: 5900415. doi: 10.1093.
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  30. ROOS I, Leray E, Frascoli F, Casey R, et al
    Delay from treatment start to full effect of immunotherapies for multiple sclerosis.
    Brain. 2020;143:2742-2756.
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    August 2020
  31. BOUMAN PM, Steenwijk MD, Pouwels PJW, Schoonheim MM, et al
    Histopathology-validated recommendations for cortical lesion imaging in multiple sclerosis.
    Brain. 2020 Aug 21. pii: 5895168. doi: 10.1093.
    >> Share

  32. CHITNIS T, Aaen G, Belman A, Benson L, et al
    Improved relapse recovery in paediatric compared to adult multiple sclerosis.
    Brain. 2020 Aug 18. pii: 5894047. doi: 10.1093.
    >> Share

    July 2020
  33. SORENSEN PS, Sellebjerg F, Hartung HP, Montalban X, et al
    The apparently milder course of multiple sclerosis: changes in the diagnostic criteria, therapy and natural history.
    Brain. 2020 Jul 24. pii: 5876125. doi: 10.1093.
    >> Share

    June 2020
  34. JACKLE K, Zeis T, Schaeren-Wiemers N, Junker A, et al
    Molecular signature of slowly expanding lesions in progressive multiple sclerosis.
    Brain. 2020 Jun 24. pii: 5861738. doi: 10.1093.
    >> Share

  35. KERBRAT A, Gros C, Badji A, Bannier E, et al
    Multiple sclerosis lesions in motor tracts from brain to cervical cord: spatial distribution and correlation with disability.
    Brain. 2020 Jun 23. pii: 5861019. doi: 10.1093.
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    May 2020
  36. FRANSEN NL, Hsiao CC, van der Poel M, Engelenburg HJ, et al
    Tissue-resident memory T cells invade the brain parenchyma in multiple sclerosis white matter lesions.
    Brain. 2020 May 13. pii: 5836675. doi: 10.1093.
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  37. MALPAS CB, Manouchehrinia A, Sharmin S, Roos I, et al
    Early clinical markers of aggressive multiple sclerosis.
    Brain. 2020 May 9. pii: 5835340. doi: 10.1093.
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  38. KADOWAKI A, Quintana FJ
    The NLRP3 inflammasome in progressive multiple sclerosis.
    Brain. 2020;143:1286-1288.
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    April 2020
  39. DIETRICH M, Koska V, Hecker C, Gottle P, et al
    Protective effects of 4-aminopyridine in experimental optic neuritis and multiple sclerosis.
    Brain. 2020 Apr 15. pii: 5820386. doi: 10.1093.
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  40. MALHOTRA S, Costa C, Eixarch H, Keller CW, et al
    NLRP3 inflammasome as prognostic factor and therapeutic target in primary progressive multiple sclerosis patients.
    Brain. 2020 Apr 13. pii: 5819591. doi: 10.1093.
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    March 2020
  41. KLEEREKOOPER I, Petzold A, Trip SA
    Anterior visual system imaging to investigate energy failure in multiple sclerosis.
    Brain. 2020 Mar 12. pii: 5804129. doi: 10.1093.
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    January 2020
  42. ROWE J
    Editorial.
    Brain. 2020;143:1.
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    November 2019
  43. MEIJER KA, Steenwijk MD, Douw L, Schoonheim MM, et al
    Long-range connections are more severely damaged and relevant for cognition in multiple sclerosis.
    Brain. 2019 Nov 15. pii: 5626204. doi: 10.1093.
    >> Share

    October 2019
  44. HAUSLER D, Torke S, Peelen E, Bertsch T, et al
    Reply: Hypercalcaemia rather than high dose vitamin D3 supplements could exacerbate multiple sclerosis.
    Brain. 2019 Oct 30. pii: 5610115. doi: 10.1093.
    >> Share

  45. SMOLDERS J, Damoiseaux J, Hupperts R
    Hypercalcaemia rather than high dose vitamin D3 supplements could exacerbate multiple sclerosis.
    Brain. 2019 Oct 30. pii: 5610116. doi: 10.1093.
    >> Share

  46. NUTMA E, Stephenson JA, Gorter RP, de Bruin J, et al
    A quantitative neuropathological assessment of translocator protein expression in multiple sclerosis.
    Brain. 2019 Oct 3. pii: 5580333. doi: 10.1093.
    >> Share

    September 2019
  47. ELLIOTT C, Belachew S, Wolinsky JS, Hauser SL, et al
    Chronic white matter lesion activity predicts clinical progression in primary progressive multiple sclerosis.
    Brain. 2019;142:2787-2799.
    >> Share

  48. PENNER IK, Hartung HP
    The dark side of the moon: looking beyond beneficial effects of cannabis use in multiple sclerosis.
    Brain. 2019;142:2552-2555.
    >> Share

    August 2019
  49. MORQUETTE B, Juzwik CA, Drake SS, Charabati M, et al
    MicroRNA-223 protects neurons from degeneration in experimental autoimmune encephalomyelitis.
    Brain. 2019 Aug 14. pii: 5549993. doi: 10.1093.
    >> Share

  50. BROWNLEE WJ, Altmann DR, Prados F, Miszkiel KA, et al
    Early imaging predictors of long-term outcomes in relapse-onset multiple sclerosis.
    Brain. 2019;142:2276-2287.
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    July 2019
  51. FEINSTEIN A, Meza C, Stefan C, Staines RW, et al
    Coming off cannabis: a cognitive and magnetic resonance imaging study in patients with multiple sclerosis.
    Brain. 2019 Jul 30. pii: 5541023. doi: 10.1093.
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  52. WENTLING M, Lopez-Gomez C, Park HJ, Amatruda M, et al
    A metabolic perspective on CSF-mediated neurodegeneration in multiple sclerosis.
    Brain. 2019 Jul 15. pii: 5531715. doi: 10.1093.
    >> Share

  53. HAUSLER D, Torke S, Peelen E, Bertsch T, et al
    High dose vitamin D exacerbates central nervous system autoimmunity by raising T-cell excitatory calcium.
    Brain. 2019 Jul 13. pii: 5532100. doi: 10.1093.
    >> Share

  54. FITZGERALD KC, Kim K, Smith MD, Aston SA, et al
    Early complement genes are associated with visual system degeneration in multiple sclerosis.
    Brain. 2019 Jul 9. pii: 5530228. doi: 10.1093.
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  55. ROPELE S, Fazekas F
    Quantification of cortical damage in multiple sclerosis using DTI remains a challenge.
    Brain. 2019;142:1848-1850.
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    June 2019
  56. FILIPPI M, Preziosa P, Banwell BL, Barkhof F, et al
    Assessment of lesions on magnetic resonance imaging in multiple sclerosis: practical guidelines.
    Brain. 2019 Jun 17. pii: 5519813. doi: 10.1093.
    >> Share

  57. PREZIOSA P, Kiljan S, Steenwijk MD, Meani A, et al
    Axonal degeneration as substrate of fractional anisotropy abnormalities in multiple sclerosis cortex.
    Brain. 2019 Jun 5. pii: 5511700. doi: 10.1093.
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    May 2019
  58. MUNK NIELSEN N, Corn G, Frisch M, Stenager E, et al
    Multiple sclerosis among first- and second-generation immigrants in Denmark: a population-based cohort study.
    Brain. 2019 May 13. pii: 5488579. doi: 10.1093.
    >> Share

  59. GIOVANNONI G
    Survival: the ultimate long-term outcome in multiple sclerosis.
    Brain. 2019;142:1166-1167.
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    April 2019
  60. WEKERLE H
    Secondary progressive multiple sclerosis and the gut-brain axis.
    Brain. 2019;142:838-840.
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    March 2019
  61. KINGWELL E, Leray E, Zhu F, Petkau J, et al
    Multiple sclerosis: effect of beta interferon treatment on survival.
    Brain. 2019 Mar 18. pii: 5382233. doi: 10.1093.
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  62. HOHLFELD R
    Immune dysbalance in childhood multiple sclerosis: a 'chicken or the egg' conundrum.
    Brain. 2019;142:490-492.
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    February 2019
  63. KADOWAKI A, Saga R, Lin Y, Sato W, et al
    Gut microbiota-dependent CCR9+CD4+ T cells are altered in secondary progressive multiple sclerosis.
    Brain. 2019 Feb 15. pii: 5321131. doi: 10.1093.
    >> Share

  64. MEXHITAJ I, Nyirenda MH, Li R, O'Mahony J, et al
    Abnormal effector and regulatory T cell subsets in paediatric-onset multiple sclerosis.
    Brain. 2019 Feb 12. pii: 5316384. doi: 10.1093.
    >> Share

    January 2019
  65. EDEN D, Gros C, Badji A, Dupont SM, et al
    Spatial distribution of multiple sclerosis lesions in the cervical spinal cord.
    Brain. 2019 Jan 30. pii: 5304670. doi: 10.1093.
    >> Share

  66. NTRANOS A, Ntranos V, Bonnefil V, Liu J, et al
    Fumarates target the metabolic-epigenetic interplay of brain-homing T cells in multiple sclerosis.
    Brain. 2019 Jan 28. pii: 5303708. doi: 10.1093.
    >> Share

  67. CHEN Y, Podojil JR, Kunjamma RB, Jones J, et al
    Sephin1, which prolongs the integrated stress response, is a promising therapeutic for multiple sclerosis.
    Brain. 2019 Jan 17. pii: 5289373. doi: 10.1093.
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    December 2018
  68. VON ESSEN MR, Ammitzboll C, Hansen RH, Petersen ERS, et al
    Proinflammatory CD20+ T cells in the pathogenesis of multiple sclerosis.
    Brain. 2018 Dec 17. pii: 5250831. doi: 10.1093.
    >> Share

  69. KAUNZNER UW, Kang Y, Zhang S, Morris E, et al
    Quantitative susceptibility mapping identifies inflammation in a subset of chronic multiple sclerosis lesions.
    Brain. 2018 Dec 15. pii: 5250435. doi: 10.1093.
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    November 2018
  70. ZALC B
    One hundred and fifty years ago Charcot reported multiple sclerosis as a new neurological disease.
    Brain. 2018 Nov 20. pii: 5194497. doi: 10.1093.
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  71. ALY L, Korn T
    Multiple sclerosis: is it all black and white in optical coherence tomography?
    Brain. 2018;141:3088-3091.
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    October 2018
  72. CALDITO NG, Saidha S, Sotirchos ES, Dewey BE, et al
    Brain and retinal atrophy in African-Americans versus Caucasian-Americans with multiple sclerosis: a longitudinal study.
    Brain. 2018 Oct 11. pii: 5127751. doi: 10.1093.
    >> Share

    September 2018
  73. BAKER D, Pryce G, Amor S, Giovannoni G, et al
    Learning from other autoimmunities to understand targeting of B cells to control multiple sclerosis.
    Brain. 2018 Sep 12. pii: 5095715. doi: 10.1093.
    >> Share

  74. EIJLERS AJC, van Geest Q, Dekker I, Steenwijk MD, et al
    Predicting cognitive decline in multiple sclerosis: a 5-year follow-up study.
    Brain. 2018;141:2605-2618.
    >> Share

    June 2018
  75. MACHADO-SANTOS J, Saji E, Troscher AR, Paunovic M, et al
    The compartmentalized inflammatory response in the multiple sclerosis brain is composed of tissue-resident CD8+ T lymphocytes and B cells.
    Brain. 2018 Jun 4. pii: 5032773. doi: 10.1093.
    >> Share

  76. STANKOFF B, Louapre C
    Can we use regional grey matter atrophy sequence to stage neurodegeneration in multiple sclerosis?
    Brain. 2018;141:1580-1583.
    >> Share

    May 2018
  77. CAMARA-LEMARROY CR, Metz L, Meddings JB, Sharkey KA, et al
    The intestinal barrier in multiple sclerosis: implications for pathophysiology and therapeutics.
    Brain. 2018 May 30. pii: 5025744. doi: 10.1093.
    >> Share

  78. BARRO C, Benkert P, Disanto G, Tsagkas C, et al
    Serum neurofilament as a predictor of disease worsening and brain and spinal cord atrophy in multiple sclerosis.
    Brain. 2018 May 30. pii: 5025690. doi: 10.1093.
    >> Share

  79. ESHAGHI A, Marinescu RV, Young AL, Firth NC, et al
    Progression of regional grey matter atrophy in multiple sclerosis.
    Brain. 2018 May 8. pii: 4993898. doi: 10.1093.
    >> Share

    April 2018
  80. CONRAD BN, Barry RL, Rogers BP, Maki S, et al
    Multiple sclerosis lesions affect intrinsic functional connectivity of the spinal cord.
    Brain. 2018 Apr 10. pii: 4965865. doi: 10.1093.
    >> Share

  81. VAN LANGELAAR J, van der Vuurst de Vries RM, Janssen M, Wierenga-Wolf AF, et al
    T helper 17.1 cells associate with multiple sclerosis disease activity: perspectives for early intervention.
    Brain. 2018 Apr 5. pii: 4961484. doi: 10.1093.
    >> Share

    March 2018
  82. STEYERBERG EW, Claggett B
    Towards personalized therapy for multiple sclerosis: limitations of observational data.
    Brain. 2018 Mar 3. pii: 4919652. doi: 10.1093.
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  83. KALINCIK T
    Reply: Towards personalized therapy for multiple sclerosis: limitations of observational data.
    Brain. 2018 Mar 3. pii: 4919653. doi: 10.1093.
    >> Share

  84. STEPHENSON EL, Mishra MK, Moussienko D, Laflamme N, et al
    Chondroitin sulfate proteoglycans as novel drivers of leucocyte infiltration in multiple sclerosis.
    Brain. 2018 Mar 1. pii: 4915907. doi: 10.1093.
    >> Share

    February 2018
  85. ARRAMBIDE G, Tintore M, Espejo C, Auger C, et al
    The value of oligoclonal bands in the multiple sclerosis diagnostic criteria.
    Brain. 2018 Feb 16. pii: 4866204. doi: 10.1093.
    >> Share

    January 2018
  86. SMETS I, Fiddes B, Garcia-Perez JE, He D, et al
    Multiple sclerosis risk variants alter expression of co-stimulatory genes in B cells.
    Brain. 2018 Jan 18. pii: 4817414. doi: 10.1093.
    >> Share

    October 2017
  87. GRANBERG T, Fan Q, Treaba CA, Ouellette R, et al
    In vivo characterization of cortical and white matter neuroaxonal pathology in early multiple sclerosis.
    Brain. 2017 Oct 10. doi: 10.1093.
    >> Share

    September 2017
  88. ROCCA MA, Sormani MP, Rovaris M, Caputo D, et al
    Long-term disability progression in primary progressive multiple sclerosis: a 15-year study.
    Brain. 2017 Sep 27. doi: 10.1093.
    >> Share

  89. DATTA G, Colasanti A, Rabiner EA, Gunn RN, et al
    Neuroinflammation and its relationship to changes in brain volume and white matter lesions in multiple sclerosis.
    Brain. 2017 Sep 23. doi: 10.1093.
    >> Share

  90. KALINCIK T, Manouchehrinia A, Sobisek L, Jokubaitis V, et al
    Towards personalized therapy for multiple sclerosis: prediction of individual treatment response.
    Brain. 2017;140:2426-2443.
    >> Share

    July 2017
  91. SCOLDING NJ, Pasquini M, Reingold SC, Cohen JA, et al
    Cell-based therapeutic strategies for multiple sclerosis.
    Brain. 2017 Jul 21. doi: 10.1093.
    >> Share

    May 2017
  92. ZRZAVY T, Hametner S, Wimmer I, Butovsky O, et al
    Loss of 'homeostatic' microglia and patterns of their activation in active multiple sclerosis.
    Brain. 2017 May 24. doi: 10.1093.
    >> Share

  93. HACOHEN Y, Ciccarelli O, Hemingway C
    Abnormal white matter development in children with multiple sclerosis and monophasic acquired demyelination.
    Brain. 2017;140:1172-1174.
    >> Share

    April 2017
  94. EL BEHI M, Sanson C, Bachelin C, Guillot-Noel L, et al
    Adaptive human immunity drives remyelination in a mouse model of demyelination.
    Brain. 2017;140:967-980.
    >> Share

    March 2017
  95. LONGONI G, Brown RA, MomayyezSiahkal P, Elliott C, et al
    White matter changes in paediatric multiple sclerosis and monophasic demyelinating disorders.
    Brain. 2017 Mar 14. doi: 10.1093.
    >> Share

  96. JURYNCZYK M, Geraldes R, Probert F, Woodhall MR, et al
    Distinct brain imaging characteristics of autoantibody-mediated CNS conditions and multiple sclerosis.
    Brain. 2017;140:617-627.
    >> Share

    January 2017
  97. BROWN JW, Pardini M, Brownlee WJ, Fernando K, et al
    An abnormal periventricular magnetization transfer ratio gradient occurs early in multiple sclerosis.
    Brain. 2017 Jan 2. pii: aww296. doi: 10.1093.
    >> Share

    October 2016
  98. CORREALE J, Gaitan MI, Ysrraelit MC, Fiol MP, et al
    Progressive multiple sclerosis: from pathogenic mechanisms to treatment.
    Brain. 2016.
    >> Share


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