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Cancer Res
    April 2024
  1. FRITSCH EF, Ott PA
    Personalized Cancer Vaccines Directed against Tumor Mutations: Building Evidence from Mice to Humans.
    Cancer Res. 2024;84:953-955.
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    January 2024
  2. XU X, Bok I, Jasani N, Wang K, et al
    PTEN Lipid Phosphatase Activity Suppresses Melanoma Formation by Opposing an AKT/mTOR/FRA1 Signaling Axis.
    Cancer Res. 2024 Jan 9:OF1-OF17. doi: 10.1158/0008-5472.CAN-23-1730.
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    November 2023
  3. TAO H, Jin C, Zhou L, Deng Z, et al
    PRMT1 inhibition activates the interferon pathway to potentiate antitumor immunity and enhance checkpoint blockade efficacy in melanoma.
    Cancer Res. 2023 Nov 22. doi: 10.1158/0008-5472.CAN-23-1082.
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    October 2023
  4. BIEBERICH F, Reddy ST
    The Unexpected Benefit of TCR Cross-Reactivity in Cancer Immunotherapy.
    Cancer Res. 2023;83:3168-3169.
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    September 2023
  5. FERRETTI LP, Bohi F, Leslie Pedrioli DM, Cheng PF, et al
    Combinatorial treatment with PARP and MAPK inhibitors overcomes phenotype switch-driven drug resistance in advanced melanoma.
    Cancer Res. 2023 Sep 20. doi: 10.1158/0008-5472.CAN-23-0485.
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  6. SHI J, Jiao T, Guo Q, Weng W, et al
    A cell surface-binding antibody atlas nominates a MUC18-directed antibody-drug conjugate for targeting melanoma.
    Cancer Res. 2023 Sep 5. doi: 10.1158/0008-5472.CAN-23-1356.
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    June 2023
  7. ADAKU N, Ostendorf BN, Mei W, Tavazoie SF, et al
    Apolipoprotein E2 Stimulates Protein Synthesis and Promotes Melanoma Progression.
    Cancer Res. 2023 Jun 19:CAN-23-1252. doi: 10.1158/0008-5472.CAN-23-1252.
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    May 2023
  8. KIM D, An L, Moon J, Maymi VI, et al
    Ccr2+ monocyte-derived macrophages influence trajectories of acquired therapy resistance in Braf-mutant melanoma.
    Cancer Res. 2023 May 17:CAN-22-2841. doi: 10.1158/0008-5472.CAN-22-2841.
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    April 2023
  9. PARK HR, Shiva A, Cummings P, Kim S, et al
    Angiopoietin-2-dependent spatial vascular destabilization promotes T-cell exclusion and limits immunotherapy in melanoma.
    Cancer Res. 2023 Apr 24:CAN-22-2838. doi: 10.1158/0008-5472.CAN-22-2838.
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    March 2023
  10. EICHHOFF OM, Stoffel CI, Kasler J, Briker L, et al
    ROS Induction Targets Persister Cancer Cells with Low Metabolic Activity in NRAS-Mutated Melanoma.
    Cancer Res. 2023 Mar 22:OF1-OF19. doi: 10.1158/0008-5472.CAN-22-1826.
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    January 2023
  11. SUN Y, Li X, Yin C, Zhang J, et al
    AMPK phosphorylates ZDHHC13 to increase MC1R activity and suppress melanomagenesis.
    Cancer Res. 2023 Jan 26:CAN-22-2595. doi: 10.1158/0008-5472.CAN-22-2595.
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    November 2022
  12. ABECUNAS C, Whitehead CE, Ziemke EK, Baumann DG, et al
    Loss of NF1 in melanoma confers sensitivity to SYK kinase inhibition.
    Cancer Res. 2022 Nov 21:CAN-22-0883. doi: 10.1158/0008-5472.CAN-22-0883.
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  13. ZERHOUNI M, Piskounova E
    Running to Outcompete Metastasis.
    Cancer Res. 2022;82:4124-4125.
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  14. SHEINBOIM D, Parikh S, Manich P, Markus I, et al
    An Exercise-Induced Metabolic Shield in Distant Organs Blocks Cancer Progression and Metastatic Dissemination.
    Cancer Res. 2022;82:4164-4178.
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    October 2022
  15. GAMBI G, Mengus G, Davidson G, Demesmaeker E, et al
    The lncRNA LENOX interacts with RAP2C to regulate metabolism and promote resistance to MAPK inhibition in melanoma.
    Cancer Res. 2022 Oct 10. pii: 709677. doi: 10.1158/0008-5472.CAN-22-0959.
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    September 2022
  16. SMALLEY I, Smalley KSM
    Space Is the Place: Mapping the Cell-Cell Interactions That Predict Immunotherapy Responses in Melanoma.
    Cancer Res. 2022;82:3198-3200.
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  17. XU X, Wang K, Vera O, Verma A, et al
    Gain of Chromosome 1q Perturbs a Competitive Endogenous RNA Network to Promote Melanoma Metastasis.
    Cancer Res. 2022;82:3016-3031.
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    August 2022
  18. XU X, Wang K, Vera O, Verma A, et al
    Gain of chromosome 1q perturbs a competitive endogenous RNA network to promote melanoma metastasis.
    Cancer Res. 2022 Aug 31. pii: 706990. doi: 10.1158/0008-5472.CAN-22-0283.
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  19. SCHATTON T, Itoh Y, Martins C, Rasbach E, et al
    Inhibition of melanoma cell-intrinsic Tim-3 stimulates MAPK-dependent tumorigenesis.
    Cancer Res. 2022 Aug 18. pii: 708039. doi: 10.1158/0008-5472.CAN-22-0970.
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  20. PAN D, Bao X, Hu M, Jiao M, et al
    SETDB1 Restrains Endogenous Retrovirus Expression and Antitumor Immunity during Radiotherapy.
    Cancer Res. 2022;82:2748-2760.
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    July 2022
  21. ANTORANZ A, Van Herck Y, Bolognesi MM, Lynch SM, et al
    Mapping the immune landscape in metastatic melanoma reveals localized cell-cell interactions that predict immunotherapy response.
    Cancer Res. 2022 Jul 14. pii: 707010. doi: 10.1158/0008-5472.CAN-22-0363.
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    June 2022
  22. CAI W, Nguyen MQ, Wilski NA, Purwin TJ, et al
    A Genome-wide screen identifies PDPK1 as a target to enhance the efficacy of MEK1/2 inhibitors in NRAS mutant melanoma.
    Cancer Res. 2022 Jun 3. pii: 699338. doi: 10.1158/0008-5472.CAN-21-3217.
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    May 2022
  23. BONFILL-TEIXIDOR E, Iurlaro R, Handl C, Wichmann J, et al
    Activity and resistance of a brain-permeable paradox breaker BRAF inhibitor in melanoma brain metastasis.
    Cancer Res. 2022 May 18. pii: 699020. doi: 10.1158/0008-5472.CAN-21-4152.
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  24. LUND AW
    Be Easy and Chill: Melanoma Cells Tell Lymph Node Fibroblasts to Relax.
    Cancer Res. 2022;82:1692-1694.
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  25. ROVERA C, Berestjuk I, Lecacheur M, Tavernier C, et al
    Secretion of IL1 by Dedifferentiated Melanoma Cells Inhibits JAK1-STAT3-Driven Actomyosin Contractility of Lymph Node Fibroblastic Reticular Cells.
    Cancer Res. 2022;82:1774-1788.
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  26. YU X, Cen L, Chen YA, Markowitz J, et al
    Tumor Expression Quantitative Trait Methylation Screening Reveals Distinct CpG Panels for Deconvolving Cancer Immune Signatures.
    Cancer Res. 2022;82:1724-1735.
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    April 2022
  27. CHENG Y, Bai F, Ren X, Sun R, et al
    Phosphoinositide-Binding Protein TIPE1 Promotes Alternative Activation of Macrophages and Tumor Progression via PIP3/Akt/TGFbeta Axis.
    Cancer Res. 2022;82:1603-1616.
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    February 2022
  28. GILL JG, Leef SN, Ramesh V, Martin-Sandoval MS, et al
    A short isoform of spermatogenic enzyme GAPDHS functions as a metabolic switch and limits metastasis in melanoma.
    Cancer Res. 2022 Feb 11. pii: 0008-5472.CAN-21-2062.
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  29. LI XQ, Zhang R, Lu H, Yue XM, et al
    Extracellular vesicle-packaged CDH11 and ITGA5 induce the premetastatic niche for bone colonization of breast cancer cells.
    Cancer Res. 2022 Feb 11. pii: 0008-5472.CAN-21-1331.
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    January 2022
  30. LIU T, Zhou L, Xiao Y, Andl T, et al
    BRAF Inhibitors Reprogram Cancer-Associated Fibroblasts to Drive Matrix Remodeling and Therapeutic Escape in Melanoma.
    Cancer Res. 2022 Jan 21. pii: 0008-5472.CAN-21-0614.
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  31. HANRAHAN AJ, Solit DB
    BRAF Mutations: The Discovery of Allele- and Lineage-Specific Differences.
    Cancer Res. 2022;82:12-14.
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    November 2021
  32. LIU W, Stachura P, Xu HC, Varaljai R, et al
    BAFF attenuates immunosuppressive monocytes in the melanoma tumor microenvironment.
    Cancer Res. 2021 Nov 22. pii: 0008-5472.CAN-21-1171.
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  33. TUBITA A, Lombardi Z, Tusa I, Lazzeretti A, et al
    Inhibition of ERK5 elicits cellular senescence in melanoma via the cyclin-dependent kinase inhibitor p21.
    Cancer Res. 2021 Nov 19. pii: 0008-5472.CAN-21-0993.
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  34. SUBRAMANIAN S, Daquinag AC, AghaAmiri S, Ghosh SC, et al
    Characterization of Peptides Targeting Metastatic Tumor Cells as Probes for Cancer Detection and Vehicles for Therapy Delivery.
    Cancer Res. 2021;81:5756-5764.
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  35. YOKOYAMA S, Takahashi A, Kikuchi R, Nishibu S, et al
    SOX10 regulates melanoma immunogenicity through an IRF4-IRF1 axis.
    Cancer Res. 2021 Nov 2. pii: 0008-5472.CAN-21-2078.
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  36. WU B, Ye Y, Xie S, Li Y, et al
    Megakaryocytes Mediate Hyperglycemia-Induced Tumor Metastasis.
    Cancer Res. 2021;81:5506-5522.
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    October 2021
  37. AGUIRRE-PORTOLES C, Payne R, Trautz A, Foskett JK, et al
    ZIP9 is a Druggable Determinant of Sex Differences in Melanoma.
    Cancer Res. 2021 Oct 27. pii: 0008-5472.CAN-21-0982.
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  38. LIU H, Yang J, Zhang Y, Han J, et al
    Psychologic Stress Drives Progression of Malignant Tumors via DRD2/HIF1alpha Signaling.
    Cancer Res. 2021;81:5353-5365.
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  39. SALTARI A, Dzung A, Quadri M, Tiso N, et al
    Specific activation of the CD271 intracellular domain in combination with chemotherapy or targeted therapy inhibits melanoma progression.
    Cancer Res. 2021 Oct 13. pii: 0008-5472.CAN-21-0117.
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  40. VALENCIA JC, Erwin-Cohen RA, Clavijo PE, Allen C, et al
    Myeloid derived suppressive cell expansion promotes melanoma growth and severity of autoimmunity by inhibiting CD40/IL-27 regulation in macrophages.
    Cancer Res. 2021 Oct 12. pii: 0008-5472.CAN-21-1148.
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    September 2021
  41. CAPPELLO S, Sung HM, Ickes C, Gibhardt CS, et al
    Protein signatures of NK cell-mediated melanoma killing predict response to immunotherapies.
    Cancer Res. 2021 Sep 13. pii: 0008-5472.CAN-21-0164.
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  42. XU F, Wang Z, Zhang H, Chen J, et al
    Mevalonate Blockade in Cancer Cells Triggers CLEC9A(+) Dendritic Cell-Mediated Antitumor Immunity.
    Cancer Res. 2021;81:4514-4528.
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    August 2021
  43. LIU J, Rebecca VW, Kossenkov AV, Connelly T, et al
    Neural crest-like stem cell transcriptome analysis identifies LPAR1 in melanoma progression and therapy resistance.
    Cancer Res. 2021 Aug 30. pii: 0008-5472.CAN-20-1496.
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    July 2021
  44. WHITE JR, Thompson DT, Koch KE, Kiriazov BS, et al
    AP-2alpha-mediated activation of E2F and EZH2 drives melanoma metastasis.
    Cancer Res. 2021 Jul 1. pii: 0008-5472.CAN-21-0772.
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  45. SAIDA Y, Brender JR, Yamamoto K, Mitchell JB, et al
    Multimodal Molecular Imaging Detects Early Responses to Immune Checkpoint Blockade.
    Cancer Res. 2021;81:3693-3705.
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    June 2021
  46. TEWARY P, Brooks AD, Xu YM, Wijeratne EMK, et al
    Small-Molecule Natural Product Physachenolide C Potentiates Immunotherapy Efficacy by Targeting BET Proteins.
    Cancer Res. 2021;81:3374-3386.
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  47. DE LOGU F, Marini M, Landini L, Souza Monteiro de Araujo D, et al
    Peripheral Nerve Resident Macrophages and Schwann Cells Mediate Cancer-Induced Pain.
    Cancer Res. 2021;81:3387-3401.
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  48. ZERHOUNI M, Martin AR, Furstoss N, Gutierrez VS, et al
    Dual covalent inhibition of PKM and IMPDH targets metabolism in cutaneous metastatic melanoma.
    Cancer Res. 2021 Jun 7. pii: 0008-5472.CAN-20-2114.
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  49. HAN S, Yan Y, Ren Y, Hu Y, et al
    LncRNA SAMMSON Mediates Adaptive Resistance to RAF Inhibition in BRAF-Mutant Melanoma Cells.
    Cancer Res. 2021;81:2918-2929.
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    May 2021
  50. LIU Z, Guo C, Das SK, Yu X, et al
    Engineering T Cells to Express Tumoricidal MDA-7/IL24 Enhances Cancer Immunotherapy.
    Cancer Res. 2021;81:2429-2441.
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    April 2021
  51. FUHRMAN BJ, Moore SC, Byrne C, Makhoul I, et al
    Association of the Age at Menarche with Site-Specific Cancer Risks in Pooled Data from Nine Cohorts.
    Cancer Res. 2021;81:2246-2255.
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  52. LEE M, Li J, Li J, Fang S, et al
    Tet2 Inactivation Enhances the Antitumor Activity of Tumor-Infiltrating Lymphocytes.
    Cancer Res. 2021;81:1965-1976.
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  53. LI T, Zhao L, Yang Y, Wang Y, et al
    T Cells Expanded from PD-1(+) Peripheral Blood Lymphocytes Share More Clones with Paired Tumor-Infiltrating Lymphocytes.
    Cancer Res. 2021;81:2184-2194.
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  54. KHARKWAL SS, Johndrow CT, Veerapen N, Kharkwal H, et al
    Serial Stimulation of Invariant Natural Killer T Cells with Covalently Stabilized Bispecific T-cell Engagers Generates Antitumor Immunity While Avoiding Anergy.
    Cancer Res. 2021;81:1788-1801.
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    March 2021
  55. DE SEMIR D, Bezrookove V, Nosrati M, Dar AA, et al
    Nuclear receptor coactivator NCOA3 regulates ultraviolet radiation-induced DNA damage and melanoma susceptibility.
    Cancer Res. 2021 Mar 25. pii: 0008-5472.CAN-20-3450.
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  56. IIZUKA S, Quintavalle M, Navarro JC, Gribbin KP, et al
    Serine-Threonine Kinase TAO3-Mediated Trafficking of Endosomes Containing the Invadopodia Scaffold TKS5alpha Promotes Cancer Invasion and Tumor Growth.
    Cancer Res. 2021;81:1472-1485.
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    February 2021
  57. TARTEY S, Neale G, Vogel P, Malireddi RKS, et al
    A MyD88/IL-1R axis regulates PD-1 expression on tumor-associated macrophages and sustains their immunosuppressive function in melanoma.
    Cancer Res. 2021 Feb 22. pii: 0008-5472.CAN-20-3510.
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  58. LEE S, Amgad M, Mobadersany P, McCormick M, et al
    Interactive Classification of Whole-Slide Imaging Data for Cancer Researchers.
    Cancer Res. 2021;81:1171-1177.
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  59. KARLSSON MJ, Costa Svedman F, Tebani A, Kotol D, et al
    Inflammation and apolipoproteins are potential biomarkers for stratification of cutaneous melanoma patients for immunotherapy and targeted therapy.
    Cancer Res. 2021 Feb 11. pii: 0008-5472.CAN-20-2000.
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  60. SHAMI SHAH A, Cao X, White AC, Baskin JM, et al
    PLEKHA4 Promotes Wnt/beta-catenin Signaling-Mediated G1/S Transition and Proliferation in Melanoma.
    Cancer Res. 2021 Feb 11. pii: 0008-5472.CAN-20-2584.
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  61. BOSHUIZEN J, Pencheva N, Krijgsman O, D'Empaire Altimari D, et al
    Cooperative targeting of immunotherapy-resistant melanoma and lung cancer by an AXL-targeting antibody-drug conjugate and immune checkpoint blockade.
    Cancer Res. 2021 Feb 2. pii: 0008-5472.CAN-20-0434.
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  62. HUANG L, Zhai Y, La J, Lui JW, et al
    Targeting pan-ETS factors inhibits melanoma progression.
    Cancer Res. 2021 Feb 1. pii: 0008-5472.CAN-19-1668.
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    January 2021
  63. LIU Y, Zhang T, Zhang H, Li J, et al
    Cell Softness Prevents Cytolytic T-cell Killing of Tumor-Repopulating Cells.
    Cancer Res. 2021;81:476-488.
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  64. KAPIAINEN E, Kihlstrom MK, Pietila R, Kaakinen M, et al
    The Amino-Terminal Oligomerization Domain of Angiopoietin-2 Affects Vascular Remodeling, Mammary Gland Tumor Growth, and Lung Metastasis in Mice.
    Cancer Res. 2021;81:129-143.
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    December 2020
  65. YAKOVIAN O, Sajman J, Arafeh R, Neve-Oz Y, et al
    MEK inhibition reverses aberrant signaling in melanoma cells through reorganization of NRas and BRAF in self nano-clusters.
    Cancer Res. 2020 Dec 21. pii: 0008-5472.CAN-20-1205.
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  66. DOUGLASS SM, Fane ME, Sanseviero E, Ecker BL, et al
    Myeloid-derived suppressor cells are a major source of Wnt5A in the melanoma microenvironment and depend on Wnt5A for full suppressive activity.
    Cancer Res. 2020 Dec 1. pii: 0008-5472.CAN-20-1238.
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    November 2020
  67. DRERUP JM, Deng Y, Pandeswara SL, Padron AS, et al
    CD122-Selective IL2 Complexes Reduce Immunosuppression, Promote Treg Fragility, and Sensitize Tumor Response to PD-L1 Blockade.
    Cancer Res. 2020;80:5063-5075.
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    October 2020
  68. PAUDEL BB, Lewis JE, Hardeman KN, Hayford CE, et al
    An Integrative Gene Expression and Mathematical Flux Balance Analysis Identifies Targetable Redox Vulnerabilities in Melanoma Cells.
    Cancer Res. 2020;80:4565-4577.
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  69. SANCHEZ-MAGRANER L, Miles J, Baker CL, Applebee CJ, et al
    High PD-1/PD-L1 Checkpoint Interaction Infers Tumor Selection and Therapeutic Sensitivity to Anti-PD-1/PD-L1 Treatment.
    Cancer Res. 2020;80:4244-4257.
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    September 2020
  70. BELLERI M, Paganini G, Coltrini D, Ronca R, et al
    BETA-GALACTOSYLCERAMIDASE PROMOTES MELANOMA GROWTH VIA MODULATION OF CERAMIDE METABOLISM.
    Cancer Res. 2020 Sep 30. pii: 0008-5472.CAN-19-3382.
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  71. ROMAGNANI A, Rottoli E, Mazza EMC, Rezzonico-Jost T, et al
    P2X7 Receptor Activity Limits Accumulation of T Cells within Tumors.
    Cancer Res. 2020;80:3906-3919.
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    August 2020
  72. SHOLL LM, Oxnard GR, Paweletz CP
    Traditional Diagnostics versus Disruptive Technology: The Role of the Pathologist in the Era of Liquid Biopsy.
    Cancer Res. 2020;80:3197-3199.
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  73. ZHANG Y, Cedervall J, Hamidi A, Herre M, et al
    Platelet-Specific PDGFB Ablation Impairs Tumor Vessel Integrity and Promotes Metastasis.
    Cancer Res. 2020;80:3345-3358.
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  74. GIURISATO E, Lonardi S, Telfer B, Lussoso S, et al
    Extracellular-Regulated Protein Kinase 5-Mediated Control of p21 Expression Promotes Macrophage Proliferation Associated with Tumor Growth and Metastasis.
    Cancer Res. 2020;80:3319-3330.
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    July 2020
  75. PORTA C, Consonni FM, Morlacchi S, Sangaletti S, et al
    Tumor-Derived Prostaglandin E2 Promotes p50 NF-kappaB-Dependent Differentiation of Monocytic MDSCs.
    Cancer Res. 2020;80:2874-2888.
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    June 2020
  76. KALLIO P, Jokinen E, Hogstrom J, Das S, et al
    Blocking Angiopoietin-2 Promotes Vascular Damage and Growth Inhibition in Mouse Tumors Treated with Small Doses of Radiation.
    Cancer Res. 2020;80:2639-2650.
    >> Share

  77. TAHTINEN S, Feola S, Capasso C, Laustio N, et al
    Exploiting Preexisting Immunity to Enhance Oncolytic Cancer Immunotherapy.
    Cancer Res. 2020;80:2575-2585.
    >> Share


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