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Articles published in
PLoS Pathog
    February 2026
  1. OLIVE ME, Callaway PC, Ilala M, Levan J, et al
    Inhibitory NK receptor expression associates with altered antimalarial function of gammadelta T cells.
    PLoS Pathog. 2026;22:e1013460.
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    January 2026
  2. LYONS FMT, Chmielewski J, Gabriela M, Chan LJ, et al
    Pfs48/45 nanobodies block Plasmodium falciparum transmission.
    PLoS Pathog. 2026;22:e1013884.
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    December 2025
  3. ZELEKE AJ, Fola AA, Tollefson GA, Niare K, et al
    High prevalence and emerging positive association of kelch13 R622I and HRP2-based RDT negativity in Plasmodium falciparum in northern Ethiopia.
    PLoS Pathog. 2025;21:e1013771.
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  4. NITARAMORN N, Kulkeaw K, Imwong M
    Experimental models of liver-stage malaria: Progress, gaps, and challenges.
    PLoS Pathog. 2025;21:e1013796.
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  5. CARLOS BC, Voges K, Affonso PHA, Jaye A, et al
    Metabolic reprogramming and gut microbiota ecology drive divergent Plasmodium vivax infection outcomes in Anopheles darlingi.
    PLoS Pathog. 2025;21:e1013823.
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  6. KANYAL A, van Gemert GJ, Wu H, van der Starre A, et al
    Inhibition of Wnt signaling in primary human hepatocytes promotes Plasmodium falciparum liver stage development.
    PLoS Pathog. 2025;21:e1013800.
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    November 2025
  7. VARSHNEY A, Pandey E, Mishra S
    Plasmodium actin-like proteins are essential for DNA segregation during male gametogenesis and malaria transmission.
    PLoS Pathog. 2025;21:e1013687.
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    October 2025
  8. POTCHEN NB, Silva TM, Kalia I, Lack JB, et al
    Nutrient stress dramatically increases malaria parasite clag2 copy number to increase host cell permeability and enable pathogen survival.
    PLoS Pathog. 2025;21:e1013321.
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  9. PASINI EM, Hakimi H, Chaiyawong N, Klop O, et al
    In vitro cultured malaria hypnozoites leave a footprint of specific metabolites.
    PLoS Pathog. 2025;21:e1013577.
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  10. ANDREW AK, Bracken TC, Nazario-Maldonado N, Russ BN, et al
    Correction: Anticoagulant therapy and altered tissue factor expression protect against experimental placental and cerebral malaria.
    PLoS Pathog. 2025;21:e1013624.
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  11. QIU D, England E, Lehane AM
    PfATP2 is a flippase on the Plasmodium falciparum surface that is important for growth and influences parasite sensitivity to antiplasmodial compounds.
    PLoS Pathog. 2025;21:e1013645.
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    September 2025
  12. KWECKA D, Wang Z, Eigminas E, Liu L, et al
    A divergent cyclic nucleotide binding protein promotes Plasmodium ookinete infection of the mosquito.
    PLoS Pathog. 2025;21:e1013467.
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    July 2025
  13. SHERRARD-SMITH E, Fillinger U, Tia JB, Winskill P, et al
    Heterogeneous impacts for malaria control from larviciding across villages and considerations for monitoring and evaluation.
    PLoS Pathog. 2025;21:e1013287.
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  14. ROPER B, Kannan D, Mathews ES, Odom John AR, et al
    Essential role for PfHSP40 in asexual replication and thermotolerance of malaria parasites.
    PLoS Pathog. 2025;21:e1013313.
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  15. ANDREW AK, Bracken TC, Nazario-Maldonado NM, Russ BN, et al
    Anticoagulant therapy and altered tissue factor expression protect against experimental placental and cerebral malaria.
    PLoS Pathog. 2025;21:e1013259.
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  16. SAMANTSIDIS GR, Kwon H, Wendland M, Fonder C, et al
    TNF signaling mediates cellular immune function and promotes malaria parasite killing in the mosquito Anopheles gambiae.
    PLoS Pathog. 2025;21:e1013329.
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  17. FENG Y, Gao W, Wang C, Shi S, et al
    Loss of serine/threonine protein phosphatase 6 severely impairs sexual stage development in malaria parasite Plasmodium berghei.
    PLoS Pathog. 2025;21:e1013318.
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  18. ALBERIONE MP, Avalos-Padilla Y, Rangel GW, Ramirez M, et al
    Hexosamine biosynthesis disruption impairs GPI production and arrests Plasmodium falciparum growth at schizont stages.
    PLoS Pathog. 2025;21:e1012832.
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  19. KETPRASIT N, Tai CW, Sharma VK, Manickam Y, et al
    Natural product-mediated reaction hijacking mechanism validates Plasmodium aspartyl-tRNA synthetase as an antimalarial drug target.
    PLoS Pathog. 2025;21:e1013057.
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  20. TISSAWAK A, Rosin Y, Katz Galay S, Qasem A, et al
    A chaperonin complex regulates organelle proteostasis in malaria parasites.
    PLoS Pathog. 2025;21:e1013275.
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  21. WALSH B, Summers RL, Rangel GW, Hagenah LM, et al
    The plasmepsin-piperaquine paradox persists in Plasmodium falciparum.
    PLoS Pathog. 2025;21:e1012779.
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    June 2025
  22. PEREZ-CANTERO A, Llora-Batlle O, Pelaez-Conde I, Martinez-Guardiola C, et al
    Heterochromatin de novo formation and maintenance in Plasmodium falciparum.
    PLoS Pathog. 2025;21:e1013137.
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  23. CEESAY S, Kampmann M, Votborg-Novel L, Hansson HS, et al
    Plasmodium falciparum expresses fewer var genes at lower levels during asymptomatic dry season infections than clinical malaria cases.
    PLoS Pathog. 2025;21:e1013210.
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    May 2025
  24. DE MENEZES MN, Ge Z, Cozijnsen A, Gras S, et al
    Long lived liver-resident memory T cells of biased specificities for abundant sporozoite antigens drive malaria protection by radiation-attenuated sporozoite vaccination.
    PLoS Pathog. 2025;21:e1012731.
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  25. NGOTHO P, Dantzler Press K, Peedell M, Muasya W, et al
    Reversible host cell surface remodelling limits immune recognition and maximizes survival of Plasmodium falciparum gametocytes.
    PLoS Pathog. 2025;21:e1013110.
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    April 2025
  26. MESEN-RAMIREZ JP, Fuchs G, Burmester J, Farias GB, et al
    HOPS/CORVET tethering complexes are critical for endocytosis and protein trafficking to invasion related organelles in malaria parasites.
    PLoS Pathog. 2025;21:e1013053.
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  27. SMITH C, Hajisadeghian M, van Noort GJVH, Deery MJ, et al
    Activity-based protein profiling reveals both canonical and novel ubiquitin pathway enzymes in Plasmodium.
    PLoS Pathog. 2025;21:e1013032.
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  28. OCHWEDO KO, Wang X, Cespedes N, Bentil RE, et al
    Regulation of diel locomotor activity and retinal responses of Anopheles stephensi by ingested histamine and serotonin is temperature- and infection-dependent.
    PLoS Pathog. 2025;21:e1013139.
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  29. BASSI MR, Cristinoi B, Buitenwerf F, Cuadrado MB, et al
    Deposition of complement regulators on the surface of Plasmodium falciparum merozoites depends on the immune status of the host.
    PLoS Pathog. 2025;21:e1013107.
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    March 2025
  30. HILDEBRAND JA, Daniels NR, Dehm EM, Fisher BD, et al
    Severe malaria enforces short-lived effector cell differentiation but does not prevent effective secondary responses by memory CD8 T cells.
    PLoS Pathog. 2025;21:e1012993.
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  31. SAAB SA, Cardoso-Jaime V, Kefi M, Dimopoulos G, et al
    Advances in the dissection of Anopheles-Plasmodium interactions.
    PLoS Pathog. 2025;21:e1012965.
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    February 2025
  32. ACEVEDO GR, Samiee SS, Ilala M, Levan J, et al
    Liver stage P. falciparum antigens highly targeted by CD4+ T cells in malaria-exposed Ugandan children.
    PLoS Pathog. 2025;21:e1012943.
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  33. TAN MH, Tiedje KE, Feng Q, Zhan Q, et al
    A paradoxical population structure of var DBLalpha types in Africa.
    PLoS Pathog. 2025;21:e1012813.
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  34. RAWAT M, Padalino G, Adika E, Okombo J, et al
    Quinoxaline-based anti-schistosomal compounds have potent anti-plasmodial activity.
    PLoS Pathog. 2025;21:e1012216.
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    January 2025
  35. SEVENO M, Loubens MN, Berry L, Graindorge A, et al
    The malaria parasite PP1 phosphatase controls the initiation of the egress pathway of asexual blood-stages by regulating the rounding-up of the vacuole.
    PLoS Pathog. 2025;21:e1012455.
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  36. SU XZ, Xu F, Stadler RV, Teklemichael AA, et al
    Malaria: Factors affecting disease severity, immune evasion mechanisms, and reversal of immune inhibition to enhance vaccine efficacy.
    PLoS Pathog. 2025;21:e1012853.
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  37. KOCHAYOO P, Moriyama S, Kotaki R, Thawornpan P, et al
    Atypical memory B cells from natural malaria infection produced broadly neutralizing antibodies against Plasmodium vivax variants.
    PLoS Pathog. 2025;21:e1012866.
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  38. RIOS KT, McGee JP, Sebastian A, Gedara SA, et al
    Widespread release of translational repression across Plasmodium's host-to-vector transmission event.
    PLoS Pathog. 2025;21:e1012823.
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  39. MCLEAN FE, Omondi BR, Diallo N, Otoboh S, et al
    Identification of novel PfEMP1 variants containing domain cassettes 11, 15 and 8 that mediate the Plasmodium falciparum virulence-associated rosetting phenotype.
    PLoS Pathog. 2025;21:e1012434.
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  40. DORIN-SEMBLAT D, Semblat JP, Hamelin R, Srivastava A, et al
    Casein Kinases 2-dependent phosphorylation of the placental ligand VAR2CSA regulates Plasmodium falciparum-infected erythrocytes cytoadhesion.
    PLoS Pathog. 2025;21:e1012861.
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  41. LEFEBVRE MJM, Degrugillier F, Arnathau C, Fontecha GA, et al
    Genomic exploration of the journey of Plasmodium vivax in Latin America.
    PLoS Pathog. 2025;21:e1012811.
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    December 2024
  42. XIE SC, Tai CW, Morton CJ, Ma L, et al
    A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo.
    PLoS Pathog. 2024;20:e1012429.
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  43. KEHRER J, Pietsch E, Ricken D, Strauss L, et al
    APEX-based proximity labeling in Plasmodium identifies a membrane protein with dual functions during mosquito infection.
    PLoS Pathog. 2024;20:e1012788.
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    November 2024
  44. ONCHURU TO, Makhulu EE, Ronnie PC, Mandere S, et al
    The Plasmodium transmission-blocking symbiont, Microsporidia MB, is vertically transmitted through Anopheles arabiensis germline stem cells.
    PLoS Pathog. 2024;20:e1012340.
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    October 2024
  45. GAO L, Zhang B, Feng Y, Yang W, et al
    Host 5-HT affects Plasmodium transmission in mosquitoes via modulating mosquito mitochondrial homeostasis.
    PLoS Pathog. 2024;20:e1012638.
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  46. FERREIRA LT, Cassiano GC, Alvarez LCS, Okombo J, et al
    A novel 4-aminoquinoline chemotype with multistage antimalarial activity and lack of cross-resistance with PfCRT and PfMDR1 mutants.
    PLoS Pathog. 2024;20:e1012627.
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  47. REYES RA, Turner L, Ssewanyana I, Jagannathan P, et al
    Differences in phenotype between long-lived memory B cells against Plasmodium falciparum merozoite antigens and variant surface antigens.
    PLoS Pathog. 2024;20:e1012661.
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  48. BARRETO C, Cardoso-Jaime V, Dimopoulos G
    A novel broad-spectrum antibacterial and anti-malarial Anopheles gambiae Cecropin promotes microbial clearance during pupation.
    PLoS Pathog. 2024;20:e1012652.
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    September 2024
  49. CHEN YA, Vickers EN, Aranda-Diaz A, Murphy M, et al
    Genomic epidemiology demonstrates spatially clustered, local transmission of Plasmodium falciparum in forest-going populations in southern Lao PDR.
    PLoS Pathog. 2024;20:e1012194.
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  50. NAHID DS, Coffey KA, Bei AK, Cordy RJ, et al
    Understanding the significance of oxygen tension on the biology of Plasmodium falciparum blood stages: From the human body to the laboratory.
    PLoS Pathog. 2024;20:e1012514.
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  51. BULLOCH MS, Huynh LK, Kennedy K, Ralton JE, et al
    Apicoplast-derived isoprenoids are essential for biosynthesis of GPI protein anchors, and consequently for egress and invasion in Plasmodium falciparum.
    PLoS Pathog. 2024;20:e1012484.
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  52. KALS E, Kals M, Lees RA, Introini V, et al
    Application of optical tweezer technology reveals that PfEBA and PfRH ligands, not PfMSP1, play a central role in Plasmodium falciparum merozoite-erythrocyte attachment.
    PLoS Pathog. 2024;20:e1012041.
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    August 2024
  53. KILPATRICK AM, Seidl CM, Ipsaro IJ, Garrison CE, et al
    Transinfection of Wolbachia wAlbB into Culex quinquefasciatus mosquitoes does not alter vector competence for Hawaiian avian malaria (Plasmodium relictum GRW4).
    PLoS Pathog. 2024;20:e1012052.
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    July 2024
  54. CHENG Q, Yang X, Zou T, Sun L, et al
    RACK1 enhances STAT3 stability and promotes T follicular helper cell development and function during blood-stage Plasmodium infection in mice.
    PLoS Pathog. 2024;20:e1012352.
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    June 2024
  55. KOUSSIS K, Haase S, Withers-Martinez C, Flynn HR, et al
    Activation loop phosphorylation and cGMP saturation of PKG regulate egress of malaria parasites.
    PLoS Pathog. 2024;20:e1012360.
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  56. MORANO AA, Ali I, Dvorin JD
    Elucidating the spatio-temporal dynamics of the Plasmodium falciparum basal complex.
    PLoS Pathog. 2024;20:e1012265.
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  57. LAURENSON AJ, Laurens MB
    A new landscape for malaria vaccine development.
    PLoS Pathog. 2024;20:e1012309.
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  58. VANHOVE M, Schwabl P, Clementson C, Early AM, et al
    Temporal and spatial dynamics of Plasmodium falciparum clonal lineages in Guyana.
    PLoS Pathog. 2024;20:e1012013.
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  59. LU F, Xu J, Liu Y, Ren Z, et al
    Plasmodium vivax serological exposure markers: PvMSP1-42-induced humoral and memory B-cell response generates long-lived antibodies.
    PLoS Pathog. 2024;20:e1012334.
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    April 2024
  60. VANDANA V, Dong S, Sheth T, Sun Q, et al
    Wolbachia infection-responsive immune genes suppress Plasmodium falciparum infection in Anopheles stephensi.
    PLoS Pathog. 2024;20:e1012145.
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    March 2024
  61. MA R, Salinas ND, Orr-Gonzalez S, Richardson B, et al
    Structure-guided design of VAR2CSA-based immunogens and a cocktail strategy for a placental malaria vaccine.
    PLoS Pathog. 2024;20:e1011879.
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  62. SHARMA S, Ramachandran A, Sharma A
    Role of riboflavin deficiency in malaria pathophysiology.
    PLoS Pathog. 2024;20:e1011991.
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    February 2024
  63. ZMARLAK NM, Lavazec C, Brito-Fravallo E, Geneve C, et al
    The Anopheles leucine-rich repeat protein APL1C is a pathogen binding factor recognizing Plasmodium ookinetes and sporozoites.
    PLoS Pathog. 2024;20:e1012008.
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    January 2024
  64. CRISPIM M, Verdaguer IB, Hernandez A, Kronenberger T, et al
    Beyond the MEP Pathway: A novel kinase required for prenol utilization by malaria parasites.
    PLoS Pathog. 2024;20:e1011557.
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  65. POLLENUS E, Possemiers H, Knoops S, Prenen F, et al
    Single cell RNA sequencing reveals endothelial cell killing and resolution pathways in experimental malaria-associated acute respiratory distress syndrome.
    PLoS Pathog. 2024;20:e1011929.
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  66. DORITCHAMOU JYA, Renn JP, Hviid L, Duffy PE, et al
    Correction: A conformational epitope in placental malaria vaccine antigen VAR2CSA: What does it teach us?
    PLoS Pathog. 2024;20:e1011503.
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    December 2023
  67. VOSS Y, Klaus S, Lichti NP, Ganter M, et al
    Malaria parasite centrins can assemble by Ca2+-inducible condensation.
    PLoS Pathog. 2023;19:e1011899.
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  68. STURMER VS, Stopper S, Binder P, Klemmer A, et al
    Progeny counter mechanism in malaria parasites is linked to extracellular resources.
    PLoS Pathog. 2023;19:e1011807.
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  69. SCHMIDT S, Wichers-Misterek JS, Behrens HM, Birnbaum J, et al
    The Kelch13 compartment contains highly divergent vesicle trafficking proteins in malaria parasites.
    PLoS Pathog. 2023;19:e1011814.
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  70. SOLEBO O, Ling L, Nwankwo I, Zhou J, et al
    Plasmodium falciparum utilizes pyrophosphate to fuel an essential proton pump in the ring stage and the transition to trophozoite stage.
    PLoS Pathog. 2023;19:e1011818.
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    November 2023
  71. RAWAT RS, Gupta A, Antil N, Bhatnagar S, et al
    Protein kinase PfPK2 mediated signalling is critical for host erythrocyte invasion by malaria parasite.
    PLoS Pathog. 2023;19:e1011770.
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  72. SEKAR P, Rajagopalan S, Shabani E, Kanjee U, et al
    NK cell-induced damage to P.falciparum-infected erythrocytes requires ligand-specific recognition and releases parasitophorous vacuoles that are phagocytosed by monocytes in the presence of immune IgG.
    PLoS Pathog. 2023;19:e1011585.
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  73. ABBERGER H, Hose M, Ninnemann A, Menne C, et al
    Neuropilin-1 identifies a subset of highly activated CD8+ T cells during parasitic and viral infections.
    PLoS Pathog. 2023;19:e1011837.
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    October 2023
  74. WIDEMAN SK, Frost JN, Richter FC, Naylor C, et al
    Cellular iron governs the host response to malaria.
    PLoS Pathog. 2023;19:e1011679.
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  75. MANDAL RK, Schmidt NW
    Mechanistic insights into the interaction between the host gut microbiome and malaria.
    PLoS Pathog. 2023;19:e1011665.
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  76. SRIBOONVORAKUL N, Chotivanich K, Silachamroon U, Phumratanaprapin W, et al
    Intestinal injury and the gut microbiota in patients with Plasmodium falciparum malaria.
    PLoS Pathog. 2023;19:e1011661.
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  77. OKADA M, Sigala PA
    The interdependence of isoprenoid synthesis and apicoplast biogenesis in malaria parasites.
    PLoS Pathog. 2023;19:e1011713.
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  78. TSEBRIY O, Khomiak A, Miguel-Blanco C, Sparkes PC, et al
    Machine learning-based phenotypic imaging to characterise the targetable biology of Plasmodium falciparum male gametocytes for the development of transmission-blocking antimalarials.
    PLoS Pathog. 2023;19:e1011711.
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    August 2023
  79. KEFI M, Balabanidou V, Sarafoglou C, Charamis J, et al
    ABCH2 transporter mediates deltamethrin uptake and toxicity in the malaria vector Anopheles coluzzii.
    PLoS Pathog. 2023;19:e1011226.
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    June 2023
  80. RAMAPRASAD A, Burda PC, Koussis K, Thomas JA, et al
    A malaria parasite phospholipase facilitates efficient asexual blood stage egress.
    PLoS Pathog. 2023;19:e1011449.
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  81. MARKWALTER CF, Petersen JEV, Zeno EE, Sumner KM, et al
    Symptomatic malaria enhances protection from reinfection with homologous Plasmodium falciparum parasites.
    PLoS Pathog. 2023;19:e1011442.
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  82. GOMEZ GM, D'Arrigo G, Sanchez CP, Berger F, et al
    PfCRT mutations conferring piperaquine resistance in falciparum malaria shape the kinetics of quinoline drug binding and transport.
    PLoS Pathog. 2023;19:e1011436.
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  83. ADAMS KL, Selland EK, Willett BC, Carew JW, et al
    Selection for insecticide resistance can promote Plasmodium falciparum infection in Anopheles.
    PLoS Pathog. 2023;19:e1011448.
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  84. WICHERS-MISTEREK JS, Krumkamp R, Held J, von Thien H, et al
    The exception that proves the rule: Virulence gene expression at the onset of Plasmodium falciparum blood stage infections.
    PLoS Pathog. 2023;19:e1011468.
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    May 2023
  85. OYONG DA, Duffy FJ, Neal ML, Du Y, et al
    Distinct immune responses associated with vaccination status and protection outcomes after malaria challenge.
    PLoS Pathog. 2023;19:e1011051.
    >> Share

  86. GUISSOU E, Da DF, Hien DFS, Yameogo KB, et al
    Intervention reducing malaria parasite load in vector mosquitoes: No impact on Plasmodium falciparum extrinsic incubation period and the survival of Anopheles gambiae.
    PLoS Pathog. 2023;19:e1011084.
    >> Share

  87. DORITCHAMOU JYA, Renn JP, Hviid L, Duffy PE, et al
    A conformational epitope in placental malaria vaccine antigen VAR2CSA: What does it teach us?
    PLoS Pathog. 2023;19:e1011370.
    >> Share

    March 2023
  88. KLUG D, Gautier A, Calvo E, Marois E, et al
    The salivary protein Saglin facilitates efficient midgut colonization of Anopheles mosquitoes by malaria parasites.
    PLoS Pathog. 2023;19:e1010538.
    >> Share

  89. VOSS Y, Klaus S, Guizetti J, Ganter M, et al
    Plasmodium schizogony, a chronology of the parasite's cell cycle in the blood stage.
    PLoS Pathog. 2023;19:e1011157.
    >> Share

  90. LOUBENS M, Marinach C, Paquereau CE, Hamada S, et al
    The claudin-like apicomplexan microneme protein is required for gliding motility and infectivity of Plasmodium sporozoites.
    PLoS Pathog. 2023;19:e1011261.
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  91. LEVRAY YS, Bana B, Tarr SJ, McLaughlin EJ, et al
    Formation of ER-lumenal intermediates during export of Plasmodium proteins containing transmembrane-like hydrophobic sequences.
    PLoS Pathog. 2023;19:e1011281.
    >> Share

    July 2021
  92. SAINI E, Sheokand PK, Sharma V, Agrawal P, et al
    Plasmodium falciparum PhIL1-associated complex plays an essential role in merozoite reorientation and invasion of host erythrocytes.
    PLoS Pathog. 2021;17:e1009750.
    >> Share


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