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Articles published in
Proc Natl Acad Sci U S A
    March 2024
  1. HAN X, Wang D, Yang L, Wang N, et al
    Activation of polyamine catabolism promotes glutamine metabolism and creates a targetable vulnerability in lung cancer.
    Proc Natl Acad Sci U S A. 2024;121:e2319429121.
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    February 2024
  2. JANSEN RA, Mainardi S, Dias MH, Bosma A, et al
    Small-molecule inhibition of MAP2K4 is synergistic with RAS inhibitors in KRAS-mutant cancers.
    Proc Natl Acad Sci U S A. 2024;121:e2319492121.
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    January 2024
  3. CHEN NY, Lin CW, Lai TY, Wu CY, et al
    Increased expression of SSEA-4 on TKI-resistant non-small cell lung cancer with EGFR-T790M mutation.
    Proc Natl Acad Sci U S A. 2024;121:e2313397121.
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  4. WU XN, Li JY, He Q, Li BQ, et al
    Targeting the PHF8/YY1 axis suppresses cancer cell growth through modulation of ROS.
    Proc Natl Acad Sci U S A. 2024;121:e2219352120.
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    December 2023
  5. LEE H, Jung JH, Ko HM, Park H, et al
    RNA-binding motif protein 10 inactivates c-Myc by partnering with ribosomal proteins uL18 and uL5.
    Proc Natl Acad Sci U S A. 2023;120:e2308292120.
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    October 2023
  6. CHUNG YH, Ortega-Rivera OA, Volckaert BA, Jung E, et al
    Viral nanoparticle vaccines against S100A9 reduce lung tumor seeding and metastasis.
    Proc Natl Acad Sci U S A. 2023;120:e2221859120.
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  7. IM SJ, Obeng RC, Nasti TH, McManus D, et al
    Characteristics and anatomic location of PD-1(+)TCF1(+) stem-like CD8 T cells in chronic viral infection and cancer.
    Proc Natl Acad Sci U S A. 2023;120:e2221985120.
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  8. GINN L, Maltas J, Baker MJ, Chaturvedi A, et al
    A TIAM1-TRIM28 complex mediates epigenetic silencing of protocadherins to promote migration of lung cancer cells.
    Proc Natl Acad Sci U S A. 2023;120:e2300489120.
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    September 2023
  9. SUAREZ JS, Novelli F, Goto K, Ehara M, et al
    HMGB1 released by mesothelial cells drives the development of asbestos-induced mesothelioma.
    Proc Natl Acad Sci U S A. 2023;120:e2307999120.
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  10. CHEN Y, Shi J, Wang X, Zhou L, et al
    An antioxidant feedforward cycle coordinated by linker histone variant H1.2 and NRF2 that drives nonsmall cell lung cancer progression.
    Proc Natl Acad Sci U S A. 2023;120:e2306288120.
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  11. LIN X, Chen Y, Lin L, Yin K, et al
    mitoSplitter: A mitochondrial variants-based method for efficient demultiplexing of pooled single-cell RNA-seq.
    Proc Natl Acad Sci U S A. 2023;120:e2307722120.
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  12. YOUSEFI M, Andrejka L, Szamecz M, Winslow MM, et al
    Fully accessible fitness landscape of oncogene-negative lung adenocarcinoma.
    Proc Natl Acad Sci U S A. 2023;120:e2303224120.
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    July 2023
  13. XIAO GY, Tan X, Rodriguez BL, Gibbons DL, et al
    EMT activates exocytotic Rabs to coordinate invasion and immunosuppression in lung cancer.
    Proc Natl Acad Sci U S A. 2023;120:e2220276120.
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    February 2023
  14. JANSSEN K, Claes F, Van de Velde D, Wehbi VL, et al
    Exploiting the intrinsic misfolding propensity of the KRAS oncoprotein.
    Proc Natl Acad Sci U S A. 2023;120:e2214921120.
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  15. WU L, Kohno M, Murakami J, Zia A, et al
    Defining and targeting tumor-associated macrophages in malignant mesothelioma.
    Proc Natl Acad Sci U S A. 2023;120:e2210836120.
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  16. CHUANG TP, Lai WY, Gabre JL, Lind DE, et al
    ALK fusion NSCLC oncogenes promote survival and inhibit NK cell responses via SERPINB4 expression.
    Proc Natl Acad Sci U S A. 2023;120:e2216479120.
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  17. BASSEY-ARCHIBONG BI, Rajendra Chokshi C, Aghaei N, Kieliszek AM, et al
    An HLA-G/SPAG9/STAT3 axis promotes brain metastases.
    Proc Natl Acad Sci U S A. 2023;120:e2205247120.
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  18. ZHANG Z, Lu YX, Liu F, Sang L, et al
    lncRNA BREA2 promotes metastasis by disrupting the WWP2-mediated ubiquitination of Notch1.
    Proc Natl Acad Sci U S A. 2023;120:e2206694120.
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  19. LI H, Liu Y, Xiao Y, Wilson CN, et al
    CRISPR metabolic screen identifies ATM and KEAP1 as targetable genetic vulnerabilities in solid tumors.
    Proc Natl Acad Sci U S A. 2023;120:e2212072120.
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    January 2023
  20. BUGIDE S, Edwards YJK, Gupta R, Green MR, et al
    CBX5 loss drives EGFR inhibitor resistance and results in therapeutically actionable vulnerabilities in lung cancer.
    Proc Natl Acad Sci U S A. 2023;120:e2218118120.
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  21. BONONI A, Wang Q, Zolondick AA, Bai F, et al
    BAP1 is a novel regulator of HIF-1alpha.
    Proc Natl Acad Sci U S A. 2023;120:e2217840120.
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    November 2022
  22. LIU W, Tai CH, Liu X, Pastan I, et al
    Anti-mesothelin immunotoxin induces mesothelioma eradication, anti-tumor immunity, and the development of tertiary lymphoid structures.
    Proc Natl Acad Sci U S A. 2022;119:e2214928119.
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    September 2022
  23. ZHOU C, Wang D, Li J, Wang Q, et al
    TGFB2-AS1 inhibits triple-negative breast cancer progression via interaction with SMARCA4 and regulating its targets TGFB2 and SOX2.
    Proc Natl Acad Sci U S A. 2022;119:e2117988119.
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    August 2022
  24. WANG Z, Zhu J, Liu Y, Wang Z, et al
    Tumor-polarized GPX3(+) AT2 lung epithelial cells promote premetastatic niche formation.
    Proc Natl Acad Sci U S A. 2022;119:e2201899119.
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    July 2022
  25. BROWN BP, Zhang YK, Kim S, Finneran P, et al
    Allele-specific activation, enzyme kinetics, and inhibitor sensitivities of EGFR exon 19 deletion mutations in lung cancer.
    Proc Natl Acad Sci U S A. 2022;119:e2206588119.
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  26. WANG D, Wang Q, Wang Y, Chen P, et al
    Targeting oncogenic KRAS with molecular brush-conjugated antisense oligonucleotides.
    Proc Natl Acad Sci U S A. 2022;119:e2113180119.
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  27. MA L, Yang F, Wu X, Mao C, et al
    Structural basis and molecular mechanism of biased GPBAR signaling in regulating NSCLC cell growth via YAP activity.
    Proc Natl Acad Sci U S A. 2022;119:e2117054119.
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    May 2022

  28. Retraction for Motiwala et al., Protein tyrosine phosphatase receptor-type O (PTPRO) exhibits characteristics of a candidate tumor suppressor in human lung cancer.
    Proc Natl Acad Sci U S A. 2022;119:e2200127119.
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  29. SCHOLZ A, DeFalco J, Leung Y, Aydin IT, et al
    Mobilization of innate and adaptive antitumor immune responses by the RNP-targeting antibody ATRC-101.
    Proc Natl Acad Sci U S A. 2022;119:e2123483119.
    >> Share

  30. FENG S, Callow MG, Fortin JP, Khan Z, et al
    A saturation mutagenesis screen uncovers resistant and sensitizing secondary KRAS mutations to clinical KRAS(G12C) inhibitors.
    Proc Natl Acad Sci U S A. 2022;119:e2120512119.
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    April 2022
  31. AHMED M, Kaur N, Cheng Q, Shanabrough M, et al
    A hypothalamic pathway for Augmentor alpha-controlled body weight regulation.
    Proc Natl Acad Sci U S A. 2022;119:e2200476119.
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    February 2022
  32. XU Q, Wang C, Zhou JX, Xu ZM, et al
    Loss of TET reprograms Wnt signaling through impaired demethylation to promote lung cancer development.
    Proc Natl Acad Sci U S A. 2022;119.
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  33. SONG NY, Li X, Ma B, Willette-Brown J, et al
    IKKalpha-deficient lung adenocarcinomas generate an immunosuppressive microenvironment by overproducing Treg-inducing cytokines.
    Proc Natl Acad Sci U S A. 2022;119.
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    December 2021
  34. SCHULT TA, Lauer MJ, Berker Y, Cardoso MR, et al
    Screening human lung cancer with predictive models of serum magnetic resonance spectroscopy metabolomics.
    Proc Natl Acad Sci U S A. 2021;118.
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  35. ZHAO X, Hu J, Li Y, Guo M, et al
    Volumetric compression develops noise-driven single-cell heterogeneity.
    Proc Natl Acad Sci U S A. 2021;118.
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    November 2021
  36. CHEON H, Holvey-Bates EG, McGrail DJ, Stark GR, et al
    PD-L1 sustains chronic, cancer cell-intrinsic responses to type I interferon, enhancing resistance to DNA damage.
    Proc Natl Acad Sci U S A. 2021;118.
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  37. DE S, Holvey-Bates EG, Mahen K, Willard B, et al
    The ubiquitin E3 ligase FBXO22 degrades PD-L1 and sensitizes cancer cells to DNA damage.
    Proc Natl Acad Sci U S A. 2021;118.
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    September 2021
  38. LLABATA P, Torres-Diz M, Gomez A, Tomas-Daza L, et al
    MAX mutant small-cell lung cancers exhibit impaired activities of MGA-dependent noncanonical polycomb repressive complex.
    Proc Natl Acad Sci U S A. 2021;118.
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  39. Correction for Jeon et al., A set of NF-kappaB-regulated microRNAs induces acquired TRAIL resistance in Lung cancer.
    Proc Natl Acad Sci U S A. 2021;118.
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    August 2021
  40. MUELLER HS, Fowler CE, Dalin S, Moiso E, et al
    Acquired resistance to PRMT5 inhibition induces concomitant collateral sensitivity to paclitaxel.
    Proc Natl Acad Sci U S A. 2021;118.
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    July 2021
  41. SALMON M, Paniagua G, Lechuga CG, Fernandez-Garcia F, et al
    KRAS4A induces metastatic lung adenocarcinomas in vivo in the absence of the KRAS4B isoform.
    Proc Natl Acad Sci U S A. 2021;118.
    >> Share

  42. LIU Z, Wang F, Liu X, Sang Y, et al
    Cell membrane-camouflaged liposomes for tumor cell-selective glycans engineering and imaging in vivo.
    Proc Natl Acad Sci U S A. 2021;118.
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    June 2021
  43. ETXEBERRIA I, Bolanos E, Teijeira A, Garasa S, et al
    Antitumor efficacy and reduced toxicity using an anti-CD137 Probody therapeutic.
    Proc Natl Acad Sci U S A. 2021;118.
    >> Share

  44. SHI L, Tan X, Liu X, Yu J, et al
    Addiction to Golgi-resident PI4P synthesis in chromosome 1q21.3-amplified lung adenocarcinoma cells.
    Proc Natl Acad Sci U S A. 2021;118.
    >> Share

  45. SANCHEZ-RIVERA FJ, Ryan J, Soto-Feliciano YM, Clare Beytagh M, et al
    Mitochondrial apoptotic priming is a key determinant of cell fate upon p53 restoration.
    Proc Natl Acad Sci U S A. 2021;118.
    >> Share

    May 2021
  46. PRADHAN AK, Maji S, Bhoopathi P, Talukdar S, et al
    Pharmacological inhibition of MDA-9/Syntenin blocks breast cancer metastasis through suppression of IL-1beta.
    Proc Natl Acad Sci U S A. 2021;118.
    >> Share

  47. DING Y, Liu Y, Lee DK, Tong Z, et al
    Cell lineage tracing links ERalpha loss in Erbb2-positive breast cancers to the arising of a highly aggressive breast cancer subtype.
    Proc Natl Acad Sci U S A. 2021;118.
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  48. TIEN JC, Chugh S, Goodrum AE, Cheng Y, et al
    AGO2 promotes tumor progression in KRAS-driven mouse models of non-small cell lung cancer.
    Proc Natl Acad Sci U S A. 2021;118.
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  49. WANG R, Godet I, Yang Y, Salman S, et al
    Hypoxia-inducible factor-dependent ADAM12 expression mediates breast cancer invasion and metastasis.
    Proc Natl Acad Sci U S A. 2021;118.
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  50. TILSTON-LUNEL A, Mazzilli S, Kingston NM, Szymaniak AD, et al
    Aberrant epithelial polarity cues drive the development of precancerous airway lesions.
    Proc Natl Acad Sci U S A. 2021;118.
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    April 2021
  51. WAN PK, Tong KC, Lok CN, Zhang C, et al
    Platinum(II) N-heterocyclic carbene complexes arrest metastatic tumor growth.
    Proc Natl Acad Sci U S A. 2021;118.
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    March 2021
  52. YANG L, Yan X, Chen J, Zhan Q, et al
    Hexokinase 2 discerns a novel circulating tumor cell population associated with poor prognosis in lung cancer patients.
    Proc Natl Acad Sci U S A. 2021;118.
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  53. BROWNLIE D, Scharenberg M, Mold JE, Hard J, et al
    Expansions of adaptive-like NK cells with a tissue-resident phenotype in human lung and blood.
    Proc Natl Acad Sci U S A. 2021;118.
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    February 2021
  54. JIMENEZ-SANCHEZ J, Bosque JJ, Jimenez Londono GA, Molina-Garcia D, et al
    Evolutionary dynamics at the tumor edge reveal metabolic imaging biomarkers.
    Proc Natl Acad Sci U S A. 2021;118.
    >> Share

    January 2021
  55. CHIBAYA L, Karim B, Zhang H, Jones SN, et al
    Mdm2 phosphorylation by Akt regulates the p53 response to oxidative stress to promote cell proliferation and tumorigenesis.
    Proc Natl Acad Sci U S A. 2021;118.
    >> Share

  56. XIAO Y, Lin FT, Lin WC
    ACTL6A promotes repair of cisplatin-induced DNA damage, a new mechanism of platinum resistance in cancer.
    Proc Natl Acad Sci U S A. 2021;118.
    >> Share


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