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Articles published in
Cancer Res
    April 2024
  1. BOUMELHA J, de Castro A, Bah N, Cha H, et al
    CRISPR-Cas9 screening identifies KRAS-induced COX-2 as a driver of immunotherapy resistance in lung cancer.
    Cancer Res. 2024 Apr 18. doi: 10.1158/0008-5472.CAN-23-2627.
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  2. RUMDE PH, Burns TF
    A Path to Persistence after EGFR Inhibition.
    Cancer Res. 2024;84:1188-1190.
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  3. PETRONI G, Pillozzi S, Antonuzzo L
    Exploiting Tertiary Lymphoid Structures to Stimulate Antitumor Immunity and Improve Immunotherapy Efficacy.
    Cancer Res. 2024;84:1199-1209.
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  4. LAU A, Blenis J, Burgos-Barragan G
    Decoding Serine Metabolism: Unveiling Novel Pathways for Evolving Cancer Therapies.
    Cancer Res. 2024;84:1191-1194.
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  5. ZHU X, Fu Z, Dutchak K, Arabzadeh A, et al
    Cotargeting CDK4/6 and BRD4 Promotes Senescence and Ferroptosis Sensitivity in Cancer.
    Cancer Res. 2024;84:1333-1351.
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  6. NAM A, Jain S, Wu C, Campos A, et al
    Integrin alphavbeta3 Upregulation in Response to Nutrient Stress Promotes Lung Cancer Cell Metabolic Plasticity.
    Cancer Res. 2024 Apr 8:OF1-OF13. doi: 10.1158/0008-5472.CAN-23-2700.
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  7. LIU Y, Murazzi I, Fuller AM, Pan H, et al
    Sarcoma Cells Secrete Hypoxia-Modified Collagen VI to Weaken the Lung Endothelial Barrier and Promote Metastasis.
    Cancer Res. 2024;84:977-993.
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  8. XU Y, Deng C, Chen H, Song Y, et al
    Osteosarcoma Cells Secrete CXCL14 That Activates Integrin alpha11beta1 on Fibroblasts to Form a Lung Metastatic Niche.
    Cancer Res. 2024;84:994-1012.
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    March 2024
  9. GAI X, Liu Y, Lan X, Chen L, et al
    Oncogenic KRAS induces arginine auxotrophy and confers a therapeutic vulnerability to SLC7A1 inhibition in non-small cell lung cancer.
    Cancer Res. 2024 Mar 19. doi: 10.1158/0008-5472.CAN-23-2095.
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  10. WANG H, Zhang Y, Tian Y, Yang W, et al
    DNA-PK-Mediated Cytoplasmic DNA Sensing Stimulates Glycolysis to Promote Lung Squamous Cell Carcinoma Malignancy and Chemoresistance.
    Cancer Res. 2024;84:688-702.
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    February 2024
  11. HU B, Wiesehofer M, de Miguel FJ, Liu Z, et al
    ASCL1 Drives Tolerance to Osimertinib in EGFR Mutant Lung Cancer in Permissive Cellular Contexts.
    Cancer Res. 2024 Feb 15. doi: 10.1158/0008-5472.CAN-23-0438.
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  12. ALEWINE C
    Macrophages Under the Influence of Tumor Mesothelin Weaken Host Defenses against Pancreatic Cancer Metastasis.
    Cancer Res. 2024;84:513-514.
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  13. RIGAMONTI A, Viatore M, Polidori R, Rahal D, et al
    Integrating AI-powered digital pathology and imaging mass cytometry identifies key classifiers of tumor cells, stroma, and immune cells in non-small cell lung cancer.
    Cancer Res. 2024 Feb 5. doi: 10.1158/0008-5472.CAN-23-1698.
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    January 2024
  14. MU M, Huang CX, Qu C, Li PL, et al
    Targeting ferroptosis-elicited inflammation suppresses hepatocellular carcinoma metastasis and enhances sorafenib efficacy.
    Cancer Res. 2024 Jan 17. doi: 10.1158/0008-5472.CAN-23-1796.
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  15. SAGGESE P, Pandey A, Alcaraz M Jr, Fung E, et al
    Glucose Deprivation Promotes Pseudohypoxia and Dedifferentiation in Lung Adenocarcinoma.
    Cancer Res. 2024;84:305-327.
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    December 2023
  16. NIU X, Martinez L
    Harnessing p53 to Improve Immunotherapy for Lung Cancer Treatment.
    Cancer Res. 2023 Dec 21:OF1-OF2. doi: 10.1158/0008-5472.CAN-23-3929.
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  17. DU M, Xin J, Zheng R, Yuan Q, et al
    CYP2A6 activity and cigarette consumption interact in smoking-related lung cancer susceptibility.
    Cancer Res. 2023 Dec 20. doi: 10.1158/0008-5472.CAN-23-0900.
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  18. MUKHOPADHYAY S, Huang HY, Lin Z, Ranieri M, et al
    Genome-Wide CRISPR Screens Identify Multiple Synthetic Lethal Targets That Enhance KRASG12C Inhibitor Efficacy.
    Cancer Res. 2023;83:4095-4111.
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  19. NIU X, Martinez L
    Harnessing p53 to improve immunotherapy for lung cancer treatment.
    Cancer Res. 2023 Dec 14. doi: 10.1158/0008-5472.CAN-23-3929.
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  20. XIA L, Liu JY, Yang MY, Zhang XH, et al
    Osimertinib covalently binds to CD34 and eliminates myeloid leukemia stem/progenitor cells.
    Cancer Res. 2023 Dec 14. doi: 10.1158/0008-5472.CAN-23-1632.
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  21. MICHAUD DE, Guerriero JL
    Myeloid cells pave the metastatic road in breast cancer.
    Cancer Res. 2023 Dec 6. doi: 10.1158/0008-5472.CAN-23-3803.
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    November 2023
  22. KO JH, Lambert KE, Bhattacharya D, Lee MC, et al
    Small cell lung cancer plasticity enables NFIB-independent metastasis.
    Cancer Res. 2023 Nov 14. doi: 10.1158/0008-5472.CAN-23-1079.
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  23. PRAHALLAD A, Weiss A, Voshol H, Kerr G, et al
    CRISPR screening identifies mechanisms of resistance to KRASG12C and SHP2 inhibitor combinations in non-small cell lung cancer.
    Cancer Res. 2023 Nov 7. doi: 10.1158/0008-5472.CAN-23-1127.
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  24. WEBER MC, Izzo LT, Oliver TG
    Epigenetic Regulators Open the Door to SCLC Plasticity.
    Cancer Res. 2023;83:3495-3497.
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  25. COTTON JL, Estrada Diez J, Sagar V, Chen J, et al
    Expressed Barcoding Enables High-Resolution Tracking of the Evolution of Drug Tolerance.
    Cancer Res. 2023;83:3611-3623.
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    October 2023
  26. HARIPRAKASH JM, Salviato E, La Mastra F, Sebestyen E, et al
    Leveraging tissue-specific enhancer-target gene regulatory networks identifies enhancer somatic mutations that functionally impact lung cancer.
    Cancer Res. 2023 Oct 19. doi: 10.1158/0008-5472.CAN-23-1129.
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  27. WU J, Subbiah V
    RETooling the RET Inhibitor Pralsetinib for ESR1 Fusion-Positive Breast Cancer and Beyond.
    Cancer Res. 2023;83:3159-3161.
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  28. YANAGAWA J, Tran LM, Salehi-Rad R, Lim RJ, et al
    Single-Cell Characterization of Pulmonary Nodules Implicates Suppression of Immunosurveillance across Early Stages of Lung Adenocarcinoma.
    Cancer Res. 2023;83:3305-3319.
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  29. NAMBIAR DK, Viswanathan V, Cao H, Zhang W, et al
    Galectin-1 Mediates Chronic STING Activation in Tumors to Promote Metastasis through MDSC Recruitment.
    Cancer Res. 2023;83:3205-3219.
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    September 2023
  30. KIM N, Hwang CY, Kim T, Kim H, et al
    A cell fate reprogramming strategy reverses epithelial-to-mesenchymal transition of lung cancer cells while avoiding hybrid states.
    Cancer Res. 2023 Sep 13:CAN-22-1559. doi: 10.1158/0008-5472.CAN-22-1559.
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    August 2023
  31. WALKER RR, Chiappinelli KB
    Protein Exaptation by Endogenous Retroviral Elements Shapes Tumor Cell Senescence and Downstream Immune Signaling.
    Cancer Res. 2023;83:2640-2642.
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  32. FAN F, Gao J, Zhao Y, Wang J, et al
    Elevated Mast Cell Abundance Is Associated with Enrichment of CCR2+ Cytotoxic T Cells and Favorable Prognosis in Lung Adenocarcinoma.
    Cancer Res. 2023;83:2690-2703.
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  33. MA S, Caligiuri MA, Yu J
    Harnessing Natural Killer Cells for Lung Cancer Therapy.
    Cancer Res. 2023 Aug 2:CAN-23-1097. doi: 10.1158/0008-5472.CAN-23-1097.
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  34. CUI W, Huang Z, Jin SG, Johnson J, et al
    Deficiency of the Polycomb Protein RYBP and TET Methylcytosine Oxidases Promotes Extensive CpG Island Hypermethylation and Malignant Transformation.
    Cancer Res. 2023;83:2480-2495.
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  35. MATHUR D, Liao C, Lin W, La Ferlita A, et al
    The ratio of key metabolic transcripts is a predictive biomarker of breast cancer metastasis to the lung.
    Cancer Res. 2023 Aug 1:CAN-23-0153. doi: 10.1158/0008-5472.CAN-23-0153.
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    July 2023
  36. ZHENG X, Sarode P, Weigert A, Turkowski K, et al
    The HDAC2-SP1 Axis Orchestrates Protumor Macrophage Polarization.
    Cancer Res. 2023;83:2345-2357.
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  37. YE F, Cai Z, Wang B, Zeng C, et al
    TGFbeta Antagonizes IFNgamma-Mediated Adaptive Immune Evasion via Activation of the AKT-Smad3-SHP1 Axis in Lung Adenocarcinoma.
    Cancer Res. 2023;83:2262-2277.
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  38. KA NL, Park MK, Kim SS, Jeon Y, et al
    NR1D1 stimulates antitumor immune responses in breast cancer by activating cGAS-STING signaling.
    Cancer Res. 2023 Jul 3:CAN-23-0329. doi: 10.1158/0008-5472.CAN-23-0329.
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    June 2023
  39. SCORTEGAGNA M, Du Y, Bradley LM, Wang K, et al
    Ubiquitin Ligases Siah1a/2 Control Alveolar Macrophage Functions to Limit Carcinogen-Induced Lung Adenocarcinoma.
    Cancer Res. 2023;83:2016-2033.
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  40. DEBLASI JM, Falzone A, Caldwell S, Prieto-Farigua N, et al
    Distinct Nrf2 Signaling Thresholds Mediate Lung Tumor Initiation and Progression.
    Cancer Res. 2023;83:1953-1967.
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  41. EXPOSITO F, Redrado M, Houry M, Hastings K, et al
    PTEN loss confers resistance to anti-PD-1 therapy in non-small cell lung cancer by increasing tumor infiltration of regulatory T cells.
    Cancer Res. 2023 Jun 13:CAN-22-3023. doi: 10.1158/0008-5472.CAN-22-3023.
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  42. MULLER N, Lorenz C, Ostendorp J, Heisel FS, et al
    Characterizing evolutionary dynamics reveals strategies to exhaust the spectrum of subclonal resistance in EGFR-mutant lung cancer.
    Cancer Res. 2023 Jun 8:CAN-22-2605. doi: 10.1158/0008-5472.CAN-22-2605.
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    May 2023
  43. HU Q, Dai J, Zhang Z, Yu H, et al
    ASS1-Mediated Reductive Carboxylation of Cytosolic Glutamine Confers Ferroptosis Resistance in Cancer Cells.
    Cancer Res. 2023;83:1646-1665.
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  44. TOMOSHIGE K, Stuart WD, Fink-Baldauf IM, Ito M, et al
    FOXA2 Cooperates with Mutant KRAS to Drive Invasive Mucinous Adenocarcinoma of the Lung.
    Cancer Res. 2023;83:1443-1458.
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  45. ZHANG H, AbdulJabbar K, Moore DA, Akarca A, et al
    Spatial Positioning of Immune Hotspots Reflects the Interplay between B and T Cells in Lung Squamous Cell Carcinoma.
    Cancer Res. 2023;83:1410-1425.
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    April 2023
  46. ZHANG H, Zhou J, Li J, Wang Z, et al
    N6-methyladenosine promotes translation of VEGFA to accelerate angiogenesis in lung cancer.
    Cancer Res. 2023 Apr 27:CAN-22-2449. doi: 10.1158/0008-5472.CAN-22-2449.
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  47. LIN Z, Li J, Zhang J, Feng W, et al
    Metabolic reprogramming driven by IGF2BP3 promotes acquired resistance to EGFR inhibitors in non-small cell lung cancer.
    Cancer Res. 2023 Apr 16:CAN-22-3059. doi: 10.1158/0008-5472.CAN-22-3059.
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  48. VRINZEN CEJ, Delfgou L, Stadhouders N, Hermens RPMG, et al
    A Systematic Review and Multilevel Regression Analysis Reveals the Comorbidity Prevalence in Cancer.
    Cancer Res. 2023;83:1147-1157.
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    March 2023
  49. HUANG X, Zhang S, Tang J, Tian T, et al
    A self-propagating c-Met-SOX2 axis drives cancer-derived IgG signaling that promotes lung cancer cell stemness.
    Cancer Res. 2023 Mar 29:CAN-22-2733. doi: 10.1158/0008-5472.CAN-22-2733.
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  50. JIN M, Liu B, Chen C, Huang Y, et al
    Genome-wide splicing QTL analysis identifies causal risk variants for non-small cell lung cancer.
    Cancer Res. 2023 Mar 20:CAN-22-3184. doi: 10.1158/0008-5472.CAN-22-3184.
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    February 2023
  51. BAO Y, Zhang S, Zhang X, Pan Y, et al
    RBM10 loss promotes EGFR-driven lung cancer and confers sensitivity to spliceosome inhibition.
    Cancer Res. 2023 Feb 28:CAN-22-1549. doi: 10.1158/0008-5472.CAN-22-1549.
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  52. MANDELL JD, Cannataro VL, Townsend JP
    Estimation of Neutral Mutation Rates and Quantification of Somatic Variant Selection Using cancereffectsizeR.
    Cancer Res. 2023;83:500-505.
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  53. LUO Y, Liang H
    Cancer Cells Employ the Most Prolific RNA Editors: A Closer Look at the Single-Cell Level.
    Cancer Res. 2023;83:351-353.
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  54. CHAN TW, Dodson JP, Arbet J, Boutros PC, et al
    Single-Cell Analysis in Lung Adenocarcinoma Implicates RNA Editing in Cancer Innate Immunity and Patient Prognosis.
    Cancer Res. 2023;83:374-385.
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    January 2023
  55. CHENG LH, Hsu CC, Tsai HW, Liao WY, et al
    ASPM activates Hedgehog and Wnt signaling to promote small cell lung cancer stemness and progression.
    Cancer Res. 2023 Jan 13:CAN-22-2496. doi: 10.1158/0008-5472.CAN-22-2496.
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    December 2022
  56. WEIGEL C, Maczis MA, Palladino END, Green CD, et al
    Sphingosine kinase 2 in stromal fibroblasts creates a hospitable tumor microenvironment in breast cancer.
    Cancer Res. 2022 Dec 21:CAN-22-1638. doi: 10.1158/0008-5472.CAN-22-1638.
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  57. LONG LL, Ma SC, Guo ZQ, Zhang YP, et al
    PARP inhibition induces synthetic lethality and adaptive immunity in LKB1-mutant lung cancer.
    Cancer Res. 2022 Dec 13:CAN-22-1740. doi: 10.1158/0008-5472.CAN-22-1740.
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  58. GAN B
    A Time and Place for Inhibiting Autophagy.
    Cancer Res. 2022;82:4322-4324.
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    November 2022
  59. VAISHNAVI A, Juan J, Jacob M, Stehn C, et al
    Transposon Mutagenesis Reveals RBMS3 Silencing as a Promoter of Malignant Progression of BRAFV600E-Driven Lung Tumorigenesis.
    Cancer Res. 2022;82:4261-4273.
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  60. ZHU LY, Yuan JB, Zhang L, He CX, et al
    Loss of MLL Induces Epigenetic Dysregulation of Rasgrf1 to Attenuate Kras-Driven Lung Tumorigenesis.
    Cancer Res. 2022;82:4153-4163.
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  61. VAN GINDERACHTER JA
    The Heat Is On: 20-HETE Instructs an Immunosuppressive Phenotype in Cancer-Associated Fibroblasts.
    Cancer Res. 2022;82:3882-3883.
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  62. SCHARPF RB, Balan A, Ricciuti B, Fiksel J, et al
    Genomic Landscapes and Hallmarks of Mutant RAS in Human Cancers.
    Cancer Res. 2022;82:4058-4078.
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  63. ROH W, Geffen Y, Cha H, Miller M, et al
    High-Resolution Profiling of Lung Adenocarcinoma Identifies Expression Subtypes with Specific Biomarkers and Clinically Relevant Vulnerabilities.
    Cancer Res. 2022;82:3917-3931.
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    October 2022
  64. LI M, Mok K, Mok T
    A Detouring Experience Not Recommended: Lessons Learned from PF00299804.
    Cancer Res. 2022;82:3662-3664.
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  65. ZHU Q, Zhang C, Qu T, Lu X, et al
    MNX1-AS1 promotes phase separation of IGF2BP1 to drive c-Myc-mediated cell cycle progression and proliferation in lung cancer.
    Cancer Res. 2022 Oct 10. pii: 709670. doi: 10.1158/0008-5472.CAN-22-1289.
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  66. LUO MY, Zhou Y, Gu WM, Wang C, et al
    Metabolic and Nonmetabolic Functions of PSAT1 Coordinate Signaling Cascades to Confer EGFR Inhibitor Resistance and Drive Progression in Lung Adenocarcinoma.
    Cancer Res. 2022;82:3516-3531.
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  67. DENG H, Lin C, Garcia-Gerique L, Fu S, et al
    A Novel Selective Inhibitor JBI-589 Targets PAD4-Mediated Neutrophil Migration to Suppress Tumor Progression.
    Cancer Res. 2022;82:3561-3572.
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    September 2022
  68. KHAYATI K, Bhatt V, Lan T, Alogaili F, et al
    Transient Systemic Autophagy Inhibition is Selectively and Irreversibly Deleterious to Lung Cancer.
    Cancer Res. 2022 Sep 26. pii: 709374. doi: 10.1158/0008-5472.CAN-22-1039.
    >> Share

  69. KIM KB, Kim DW, Kim Y, Tang J, et al
    WNT5A-RHOA signaling is a driver of tumorigenesis and represents a therapeutically actionable vulnerability in small cell lung cancer.
    Cancer Res. 2022 Sep 14. pii: 709197. doi: 10.1158/0008-5472.CAN-22-1170.
    >> Share

  70. WOO XY, Srivastava A, Mack PC, Graber JH, et al
    A Genomically and Clinically Annotated Patient-Derived Xenograft (PDX) Resource for Preclinical Research in Non-Small Cell Lung Cancer.
    Cancer Res. 2022 Sep 7. pii: 709108. doi: 10.1158/0008-5472.CAN-22-0948.
    >> Share

  71. YOSHIDA R, Saigi M, Tani T, Springer BF, et al
    MET-induced CD73 restrains STING-mediated immunogenicity of EGFR-mutant lung cancer.
    Cancer Res. 2022 Sep 6. pii: 708983. doi: 10.1158/0008-5472.CAN-22-0770.
    >> Share

  72. TREFZER TB, Schneider MA, Jechow K, Chua RL, et al
    Intratumoral Heterogeneity and Immune Modulation in Lung Adenocarcinoma in Female Smokers and Never Smokers.
    Cancer Res. 2022;82:3116-3129.
    >> Share

    August 2022
  73. CHOI YJ, Kim DS, Sung YH, Kim DH, et al
    Retraction: The Reversible Fourth-Generation EGFR Tyrosine Kinase Inhibitor OBX02-011 Overcomes C797S-Mediated Resistance in Lung Cancer.
    Cancer Res. 2022 Aug 26:OF1. doi: 10.1158/0008-5472.CAN-22-2507.
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  74. CHOI YJ, Kim DS, Sung YH, Kim DH, et al
    Correction: The Reversible Fourth-Generation EGFR Tyrosine Kinase Inhibitor OBX02-011 Overcomes C797S-Mediated Resistance in Lung Cancer.
    Cancer Res. 2022 Aug 25:OF1. doi: 10.1158/0008-5472.CAN-22-2377.
    >> Share

  75. CHEN X, Liu Y, Wang Y, Wang C, et al
    CYP4F2-catalyzed metabolism of arachidonic acid promotes stromal cell-mediated immunosuppression in non-small cell lung cancer.
    Cancer Res. 2022 Aug 24. pii: 708709. doi: 10.1158/0008-5472.CAN-21-4029.
    >> Share

  76. ROLFO C, Malapelle U, Russo A
    Expanding the Full Potential of Liquid Biopsies for Lung Cancer Patients.
    Cancer Res. 2022;82:2826-2828.
    >> Share

  77. CHRISTENSEN DS, Ahrenfeldt J, Sokac M, Kisistok J, et al
    Treatment Represents a Key Driver of Metastatic Cancer Evolution.
    Cancer Res. 2022;82:2918-2927.
    >> Share

  78. HONG CL, Yu IS, Pai CH, Chen JS, et al
    CD248 regulates Wnt signaling in pericytes to promote angiogenesis and tumor growth in lung cancer.
    Cancer Res. 2022 Aug 11. pii: 707659. doi: 10.1158/0008-5472.CAN-22-1695.
    >> Share

  79. BOUMELHA J, de Carne Trecesson S, Law EK, Romero-Clavijo P, et al
    An immunogenic model of KRAS-mutant lung cancer enables evaluation of targeted therapy and immunotherapy combinations.
    Cancer Res. 2022 Aug 5. pii: 707449. doi: 10.1158/0008-5472.CAN-22-0325.
    >> Share

  80. THEGE FI, Rupani DN, Barathi BB, Manning SL, et al
    A Programmable In Vivo CRISPR Activation Model Elucidates the Oncogenic and Immunosuppressive Functions of MYC in Lung Adenocarcinoma.
    Cancer Res. 2022;82:2761-2776.
    >> Share

    July 2022
  81. LEE J, Bayik D, Lathia JD
    Preinvasive to Invasive: PD-1-Expressing Macrophages Shift Lung Cancer into High Gear.
    Cancer Res. 2022;82:2515-2516.
    >> Share

  82. JANG HJ, Lee HS, Yu W, Ramineni M, et al
    Therapeutic Targeting of Macrophage Plasticity Remodels the Tumor-Immune Microenvironment.
    Cancer Res. 2022;82:2593-2609.
    >> Share

    June 2022
  83. KELENIS DP, Rodarte KE, Kollipara RK, Pozo K, et al
    Inhibition of karyopherin beta1-mediated nuclear import disrupts oncogenic lineage- defining transcription factor activity in small cell lung cancer.
    Cancer Res. 2022 Jun 24. pii: 705062. doi: 10.1158/0008-5472.CAN-21-3713.
    >> Share

  84. NAIR VS, Hui AB, Chabon JJ, Shahrokh Esfahani M, et al
    Genomic Profiling of Bronchoalveolar Lavage Fluid in Lung Cancer.
    Cancer Res. 2022 Jun 24. pii: 705060. doi: 10.1158/0008-5472.CAN-22-0554.
    >> Share

  85. KARLOW JA, Devarakonda S, Xing X, Jang HS, et al
    Developmental pathways are epigenetically reprogrammed during lung cancer brain metastasis.
    Cancer Res. 2022 Jun 15. pii: 704908. doi: 10.1158/0008-5472.CAN-21-4160.
    >> Share

  86. CHOI YJ, Kim DS, Hoon Sung Y, Kim DH, et al
    The reversible fourth-generation EGFR tyrosine kinase inhibitor OBX02-011 overcomes C797S-mediated resistance in lung cancer.
    Cancer Res. 2022 Jun 14. pii: 704898. doi: 10.1158/0008-5472.CAN-22-0394.
    >> Share

    April 2022
  87. YOUSEFI M, Boross G, Weiss C, Murray CW, et al
    Combinatorial Inactivation of Tumor Suppressors Efficiently Initiates Lung Adenocarcinoma with Therapeutic Vulnerabilities.
    Cancer Res. 2022;82:1589-1602.
    >> Share

  88. PAL AS, Agredo A, Lanman NA, Son J, et al
    Loss of KMT5C Promotes EGFR Inhibitor Resistance in NSCLC via LINC01510-Mediated Upregulation of MET.
    Cancer Res. 2022;82:1534-1547.
    >> Share

  89. WANG F, Liu Y, Qiu W, Shum E, et al
    Functional Analysis of MET Exon 14 Skipping Alteration in Cancer Invasion and Metastatic Dissemination.
    Cancer Res. 2022;82:1365-1379.
    >> Share

  90. HONG Z, Liu T, Wan L, Fa P, et al
    Targeting Squalene Epoxidase Interrupts Homologous Recombination via the ER Stress Response and Promotes Radiotherapy Efficacy.
    Cancer Res. 2022;82:1298-1312.
    >> Share

    March 2022
  91. OSBORNE JK, Minna JD
    Lung Cancer Cell of Origin: Controversy and Clinical Translational Implications.
    Cancer Res. 2022;82:972-973.
    >> Share

    February 2022
  92. SON J, Jang J, Beyett TS, Eum Y, et al
    A novel HER2-selective kinase inhibitor is effective in HER2 mutant and amplified non-small cell lung cancer.
    Cancer Res. 2022 Feb 11. pii: 0008-5472.CAN-21-2693.
    >> Share

    January 2022
  93. YIN H, Jing B, Xu D, Guo W, et al
    Identification of Active Bronchioalveolar Stem Cells as the Cell-of-Origin in Lung Adenocarcinoma.
    Cancer Res. 2022 Jan 19. pii: 0008-5472.CAN-21-2445.
    >> Share

  94. HAJ-SHOMALY J, Vorontsova A, Barenholz-Cohen T, Levi-Galibov O, et al
    T Cells Promote Metastasis by Regulating Extracellular Matrix Remodeling following Chemotherapy.
    Cancer Res. 2022;82:278-291.
    >> Share

  95. LIU X, Li Z, Wang Z, Liu F, et al
    Chromatin remodeling induced by ARID1A loss in lung cancer promotes glycolysis and confers JQ1 vulnerability.
    Cancer Res. 2022 Jan 5. pii: 0008-5472.CAN-21-0763.
    >> Share

  96. LIM SM, Kim CG, Cho BC
    Antibody-Drug Conjugates: A New Addition to the Treatment Landscape of EGFR-Mutant Non-Small Cell Lung Cancer.
    Cancer Res. 2022;82:18-20.
    >> Share

  97. ISHOLA AA, Chien CS, Yang YP, Chien Y, et al
    Oncogenic circRNA C190 Promotes Non-Small Cell Lung Cancer via Modulation of the EGFR/ERK Pathway.
    Cancer Res. 2022;82:75-89.
    >> Share

    December 2021
  98. OBA T, Kajihara R, Yokoi T, Repasky EA, et al
    Neoadjuvant In Situ Immunomodulation Enhances Systemic Antitumor Immunity against Highly Metastatic Tumors.
    Cancer Res. 2021;81:6183-6195.
    >> Share

  99. CHEN X, Zhao Y, Wang D, Lin Y, et al
    The HNF4alpha-BC200-FMR1-Positive Feedback Loop Promotes Growth and Metastasis in Invasive Mucinous Lung Adenocarcinoma.
    Cancer Res. 2021;81:5904-5918.
    >> Share

    November 2021
  100. HONG W, Li A, Liu Y, Xiao X, et al
    Clonal Hematopoiesis Mutations in Lung Cancer Patients are Associated with Lung Cancer Risk Factors.
    Cancer Res. 2021 Nov 23. pii: 0008-5472.CAN-21-1903.
    >> Share

  101. QUINTANAL-VILLALONGA A, Taniguchi H, Hao Y, Chow A, et al
    Inhibition of XPO1 sensitizes small cell lung cancer to first- and second-line chemotherapy.
    Cancer Res. 2021 Nov 23. pii: 0008-5472.CAN-21-2964.
    >> Share

  102. HONG D, Knelson EH, Li Y, Durmaz YT, et al
    Plasticity in the Absence of NOTCH Uncovers a RUNX2-Dependent Pathway in Small Cell Lung Cancer.
    Cancer Res. 2021 Nov 22. pii: 0008-5472.CAN-21-1991.
    >> Share

  103. SUBRAMANIAN S, Daquinag AC, AghaAmiri S, Ghosh SC, et al
    Characterization of Peptides Targeting Metastatic Tumor Cells as Probes for Cancer Detection and Vehicles for Therapy Delivery.
    Cancer Res. 2021;81:5756-5764.
    >> Share

  104. JANJANAM J, Pano G, Wang R, Minden-Birkenmaier BA, et al
    Matricellular Protein WISP2 Is an Endogenous Inhibitor of Collagen Linearization and Cancer Metastasis.
    Cancer Res. 2021;81:5666-5677.
    >> Share

  105. WU B, Ye Y, Xie S, Li Y, et al
    Megakaryocytes Mediate Hyperglycemia-Induced Tumor Metastasis.
    Cancer Res. 2021;81:5506-5522.
    >> Share

  106. GRISARU-TAL S, Dulberg S, Beck L, Zhang C, et al
    Metastasis-Entrained Eosinophils Enhance Lymphocyte-Mediated Antitumor Immunity.
    Cancer Res. 2021;81:5555-5571.
    >> Share

    October 2021
  107. DONE SJ, Kanwar N, Balde Z, Nair R, et al
    Heterogeneity of circulating tumor cell-associated genomic gains in breast cancer and its association with the host immune response.
    Cancer Res. 2021 Oct 28. pii: 0008-5472.CAN-21-1079.
    >> Share

  108. KUNZKE T, Prade VM, Buck A, Sun N, et al
    Patterns of carbon-bound exogenous compounds in lung cancer patients and association with disease pathophysiology.
    Cancer Res. 2021 Oct 19. pii: 0008-5472.CAN-21-1175.
    >> Share

  109. HUGGINS DN, LaRue RS, Wang Y, Knutson TP, et al
    Characterizing Macrophage Diversity in Metastasis-Bearing Lungs Reveals a Lipid-Associated Macrophage Subset.
    Cancer Res. 2021;81:5284-5295.
    >> Share

  110. HAN H, Li S, Chen T, Fitzgerald M, et al
    Targeting HER2 Exon 20 Insertion-Mutant Lung Adenocarcinoma with a Novel Tyrosine Kinase Inhibitor Mobocertinib.
    Cancer Res. 2021;81:5311-5324.
    >> Share

    September 2021
  111. ZHAO Z, Szczepanski AP, Tsuboyama N, Abdala-Valencia H, et al
    PAX9 Determines Epigenetic State Transition and Cell Fate in Cancer.
    Cancer Res. 2021;81:4696-4708.
    >> Share

  112. SATO R, Imamura K, Semba T, Tomita Y, et al
    TGFbeta Signaling Activated by Cancer-Associated Fibroblasts Determines the Histological Signature of Lung Adenocarcinoma.
    Cancer Res. 2021;81:4751-4765.
    >> Share

  113. KODAMA M, Shimura H, Tien JC, Newberg JY, et al
    Sleeping Beauty transposon mutagenesis identifies genes driving the initiation and metastasis of uterine leiomyosarcoma.
    Cancer Res. 2021 Sep 2. pii: 0008-5472.CAN-21-0356.
    >> Share

  114. LI C, Lin WY, Rizvi H, Cai H, et al
    Quantitative In Vivo Analyses Reveal a Complex Pharmacogenomic Landscape in Lung Adenocarcinoma.
    Cancer Res. 2021;81:4570-4580.
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    August 2021
  115. YU TJ, Liu YY, Li XG, Lian B, et al
    PDSS1-mediated activation of CAMK2A-STAT3 signaling promotes metastasis in triple-negative breast cancer.
    Cancer Res. 2021 Aug 18. pii: 0008-5472.CAN-21-0747.
    >> Share

  116. KOENIG MJ, Agana BA, Kaufman JM, Sharpnack MF, et al
    STK11/LKB1 Loss of Function Is Associated with Global DNA Hypomethylation and S-Adenosyl-Methionine Depletion in Human Lung Adenocarcinoma.
    Cancer Res. 2021;81:4194-4204.
    >> Share

  117. WANG X, Chen Y, Wang X, Tian H, et al
    Stem cell factor SOX2 confers ferroptosis resistance in lung cancer via upregulation of SLC7A11.
    Cancer Res. 2021 Aug 12. pii: 0008-5472.CAN-21-0567.
    >> Share

    July 2021
  118. KASHIMA Y, Shibahara D, Suzuki A, Muto K, et al
    Single-cell analyses reveal diverse mechanisms of resistance to EGFR tyrosine kinase inhibitors in lung cancer.
    Cancer Res. 2021 Jul 9. pii: 0008-5472.CAN-20-2811.
    >> Share

  119. VON ITZSTEIN MS, Gerber DE, Minna JD
    Contemporary Lung Cancer Screening and the Promise of Blood-Based Biomarkers.
    Cancer Res. 2021;81:3441-3443.
    >> Share

    June 2021
  120. LI HJ, Ke FY, Lin CC, Lu MY, et al
    ENO1 promotes lung cancer metastasis via HGFR and WNT signaling-driven epithelial-mesenchymal transition.
    Cancer Res. 2021 Jun 18. pii: 0008-5472.CAN-20-3543.
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  121. SHARIF GM, Campbell MJ, Nasir A, Sengupta S, et al
    An AIB1 isoform alters enhancer access and enables progression of early stage triple-negative breast cancer.
    Cancer Res. 2021 Jun 16. pii: 0008-5472.CAN-20-3625.
    >> Share

  122. CHANG A, Liu L, Ashby JM, Wu D, et al
    Recruitment of KMT2C/MLL3 to DNA Damage Sites Mediates DNA Damage Responses and Regulates PARP Inhibitor Sensitivity in Cancer.
    Cancer Res. 2021;81:3358-3373.
    >> Share

  123. TU HF, Ko CJ, Lee CT, Lee CF, et al
    Afatinib Exerts Immunomodulatory Effects by Targeting the Pyrimidine Biosynthesis Enzyme CAD.
    Cancer Res. 2021;81:3270-3282.
    >> Share

  124. DE LOGU F, Marini M, Landini L, Souza Monteiro de Araujo D, et al
    Peripheral Nerve Resident Macrophages and Schwann Cells Mediate Cancer-Induced Pain.
    Cancer Res. 2021;81:3387-3401.
    >> Share

  125. ISHIOKA K, Yasuda H, Hamamoto J, Terai H, et al
    Upregulation of fibroblast growth factor 9 in lung adenocarcinoma transdifferentiation to small cell lung cancer.
    Cancer Res. 2021 Jun 3. pii: 0008-5472.CAN-20-4048.
    >> Share

  126. CHABANON RM, Morel D, Eychenne T, Colmet-Daage L, et al
    PBRM1 Deficiency Confers Synthetic Lethality to DNA Repair Inhibitors in Cancer.
    Cancer Res. 2021;81:2888-2902.
    >> Share

  127. ZHANG X, Maity TK, Ross KE, Qi Y, et al
    Alterations in the Global Proteome and Phosphoproteome in Third Generation EGFR TKI Resistance Reveal Drug Targets to Circumvent Resistance.
    Cancer Res. 2021;81:3051-3066.
    >> Share

  128. KUREBAYASHI Y, Olkowski CP, Lane KC, Vasalatiy OV, et al
    Rapid Depletion of Intratumoral Regulatory T Cells Induces Synchronized CD8 T- and NK-cell Activation and IFNgamma-Dependent Tumor Vessel Regression.
    Cancer Res. 2021;81:3092-3104.
    >> Share

    May 2021
  129. DENEKA AY, Kopp MC, Nikonova AS, Gaponova AV, et al
    Nedd9 restrains autophagy to limit growth of early stage non-small cell lung cancer.
    Cancer Res. 2021 May 18. pii: 0008-5472.CAN-20-3626.
    >> Share

  130. WANG C, Meng X, Zhou Y, Yu J, et al
    Long noncoding RNA CTD-2245E15.3 promotes anabolic enzymes ACC1 and PC to support non-small cell lung cancer growth.
    Cancer Res. 2021 May 3. pii: 0008-5472.CAN-19-3806.
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  131. REN J, He J, Zhang H, Xia Y, et al
    Platelet TLR4-ERK5 Axis Facilitates NET-Mediated Capturing of Circulating Tumor Cells and Distant Metastasis after Surgical Stress.
    Cancer Res. 2021;81:2373-2385.
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    April 2021
  132. FUHRMAN BJ, Moore SC, Byrne C, Makhoul I, et al
    Association of the Age at Menarche with Site-Specific Cancer Risks in Pooled Data from Nine Cohorts.
    Cancer Res. 2021;81:2246-2255.
    >> Share

  133. KOVALENKO A, Sanin A, Kosmas K, Zhang L, et al
    Therapeutic Targeting of DGKA-Mediated Macropinocytosis Leads to Phospholipid Reprogramming in Tuberous Sclerosis Complex.
    Cancer Res. 2021;81:2086-2100.
    >> Share

  134. MUSOLF AM, Simpson CL, Moiz BA, Pikielny CW, et al
    Genetic variation and recurrent haplotypes on chromosome 6q23-25 risk locus in familial lung cancer.
    Cancer Res. 2021 Apr 14. pii: 0008-5472.CAN-20-3196.
    >> Share

  135. LI R, Salehi-Rad R, Crosson W, Momcilovic M, et al
    Inhibition of Granulocytic Myeloid-Derived Suppressor Cells Overcomes Resistance to Immune Checkpoint Inhibition in LKB1-deficient Non-Small Cell Lung Cancer.
    Cancer Res. 2021 Apr 14. pii: 0008-5472.CAN-20-3564.
    >> Share

  136. LIN EP, Huang BT, Lai WY, Tseng YT, et al
    PINK1-Mediated Inhibition of EGFR Dimerization and Activation Impedes EGFR-Driven Lung Tumorigenesis.
    Cancer Res. 2021;81:1745-1757.
    >> Share

  137. CHEN F, Chen Z, Guan T, Zhou Y, et al
    N6-methyladenosine regulates mRNA stability and translation efficiency of KRT7 to promote breast cancer lung metastasis.
    Cancer Res. 2021 Apr 1. pii: 0008-5472.CAN-20-3779.
    >> Share

    March 2021
  138. KONEN JM, Rodriguez BL, Padhye A, Ochieng JK, et al
    Dual Inhibition of MEK and AXL Targets Tumor Cell Heterogeneity and Prevents Resistant Outgrowth Mediated by the Epithelial-to-Mesenchymal Transition in NSCLC.
    Cancer Res. 2021;81:1398-1412.
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  139. DAI M, Boudreault J, Wang N, Poulet S, et al
    Differential Regulation of Cancer Progression by CDK4/6 Plays a Central Role in DNA Replication and Repair Pathways.
    Cancer Res. 2021;81:1332-1346.
    >> Share

    February 2021
  140. YU R, Longo J, van Leeuwen JE, Zhang C, et al
    Mevalonate pathway inhibition slows breast cancer metastasis via reduced N-glycosylation abundance and branching.
    Cancer Res. 2021 Feb 18. pii: 0008-5472.CAN-20-2642.
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  141. SIN TK, Zhang G, Zhang Z, Zhu JZ, et al
    Cancer-Induced Muscle Wasting Requires p38beta MAPK Activation of p300.
    Cancer Res. 2021;81:885-897.
    >> Share

  142. ZHOU J, Li Q, Cao Y
    Spatiotemporal Heterogeneity Across Metastases and Organ-Specific Response Informs Drug Efficacy and Patient Survival in Colorectal Cancer.
    Cancer Res. 2021 Feb 15. pii: 0008-5472.CAN-20-3665.
    >> Share

  143. SINGH S, Sutcliffe MD, Repich K, Atkins KA, et al
    Pan-cancer Drivers are Recurrent Transcriptional Regulatory Heterogeneities in Early-stage Luminal Breast Cancer.
    Cancer Res. 2021 Feb 2. pii: 0008-5472.CAN-20-1034.
    >> Share

  144. HILFENHAUS G, Mompeon A, Freshman J, Prajapati DP, et al
    A High-Content Screen Identifies Drugs That Restrict Tumor Cell Extravasation across the Endothelial Barrier.
    Cancer Res. 2021;81:619-633.
    >> Share

  145. CRESSWELL GM, Wang B, Kischuk EM, Broman MM, et al
    Folate Receptor Beta Designates Immunosuppressive Tumor-Associated Myeloid Cells That Can Be Reprogrammed with Folate-Targeted Drugs.
    Cancer Res. 2021;81:671-684.
    >> Share

  146. ROSSI G, Barabino E, Fedeli A, Ficarra G, et al
    Radiomic Detection of EGFR Mutations in NSCLC.
    Cancer Res. 2021;81:724-731.
    >> Share

    January 2021
  147. KOLAPALLI SP, Sahu R, Chauhan NR, Jena KK, et al
    RNA-Binding RING E3-Ligase DZIP3/hRUL138 Stabilizes Cyclin D1 to Drive Cell-Cycle and Cancer Progression.
    Cancer Res. 2021;81:315-331.
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  148. XING F, Zhao D, Wu SY, Tyagi A, et al
    Epigenetic and post-transcriptional modulation of SOS1 can promote breast cancer metastasis through obesity-activated c-Met signaling in African American women.
    Cancer Res. 2021 Jan 14. pii: 0008-5472.CAN-19-4031.
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  149. KAMIYAMA M, Augustin HG
    Alternatively Spliced Form of Angiopoietin-2 as a New Vascular Rheostat.
    Cancer Res. 2021;81:35-37.
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  150. KAPIAINEN E, Kihlstrom MK, Pietila R, Kaakinen M, et al
    The Amino-Terminal Oligomerization Domain of Angiopoietin-2 Affects Vascular Remodeling, Mammary Gland Tumor Growth, and Lung Metastasis in Mice.
    Cancer Res. 2021;81:129-143.
    >> Share

  151. JEONG GY, Park MK, Choi HJ, An HW, et al
    NSD3-Induced Methylation of H3K36 Activates NOTCH Signaling to Drive Breast Tumor Initiation and Metastatic Progression.
    Cancer Res. 2021;81:77-90.
    >> Share

    December 2020
  152. DOUGLASS SM, Fane ME, Sanseviero E, Ecker BL, et al
    Myeloid-derived suppressor cells are a major source of Wnt5A in the melanoma microenvironment and depend on Wnt5A for full suppressive activity.
    Cancer Res. 2020 Dec 1. pii: 0008-5472.CAN-20-1238.
    >> Share

    October 2020
  153. WILLS CA, Liu X, Chen L, Zhao Y, et al
    Chemotherapy-Induced Upregulation of Small Extracellular Vesicle-Associated PTX3 Accelerates Breast Cancer Metastasis.
    Cancer Res. 2020 Oct 28. pii: 0008-5472.CAN-20-1976.
    >> Share


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