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Articles published in
Proc Natl Acad Sci U S A
    July 2025
  1. WU J, Gao M, Wu X, Liu Y, et al
    PI(4)P recruits CIDE proteins to promote the formation of unilocular lipid droplets during adipogenesis and hepatic steatosis.
    Proc Natl Acad Sci U S A. 2025;122:e2504219122.
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    June 2025
  2. OZAKI MK, Zhang Y, Bartlett AQ, de Wilde E, et al
    Reproductive state controls transcription in the murine liver, with implications for breast cancer liver metastasis.
    Proc Natl Acad Sci U S A. 2025;122:e2420174122.
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    May 2025
  3. ZHANG Y, Zuo A, Ba Y, Liu S, et al
    Cancer-associated fibroblast-derived SEMA3C facilitates colorectal cancer liver metastasis via NRP2-mediated MAPK activation.
    Proc Natl Acad Sci U S A. 2025;122:e2423077122.
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  4. SAKUMA I, Gaspar RC, Nasiri AR, Dufour S, et al
    Liver lipid droplet cholesterol content is a key determinant of metabolic dysfunction-associated steatohepatitis.
    Proc Natl Acad Sci U S A. 2025;122:e2502978122.
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    February 2025
  5. QIAN X, Zhou Q, Ouyang Y, Wu X, et al
    Transferrin promotes fatty acid oxidation and liver tumor growth through PHD2-mediated PPARalpha hydroxylation in an iron-dependent manner.
    Proc Natl Acad Sci U S A. 2025;122:e2412473122.
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    January 2025
  6. SUN L, Hu P, Yang H, Ren J, et al
    ADARp110 promotes hepatocellular carcinoma progression via stabilization of CD24 mRNA.
    Proc Natl Acad Sci U S A. 2025;122:e2409724122.
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  7. XU X, Penjweini R, Szekvolgyi L, Karanyi Z, et al
    Endonuclease G promotes hepatic mitochondrial respiration by selectively increasing mitochondrial tRNA(Thr) production.
    Proc Natl Acad Sci U S A. 2025;122:e2411298122.
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  8. WANG J, Liao L, Miao B, Yang B, et al
    Deciphering the role of the MALT1-RC3H1 axis in regulating GPX4 protein stability.
    Proc Natl Acad Sci U S A. 2025;122:e2419625121.
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  9. SHI W, Yi X, Ruan H, Wang D, et al
    An animal model recapitulates human hepatic diseases associated with GATA6 mutations.
    Proc Natl Acad Sci U S A. 2025;122:e2317801121.
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    October 2024
  10. JIANG L, Qi X, Lai M, Zhou J, et al
    WDR20 prevents hepatocellular carcinoma senescence by orchestrating the simultaneous USP12/46-mediated deubiquitination of c-Myc.
    Proc Natl Acad Sci U S A. 2024;121:e2407904121.
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  11. BAI J, Jiang P, Ji L, Lam WKJ, et al
    Histone modifications of circulating nucleosomes are associated with changes in cell-free DNA fragmentation patterns.
    Proc Natl Acad Sci U S A. 2024;121:e2404058121.
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    August 2024
  12. GANGULY S, Rosenthal SB, Ishizuka K, Troutman TD, et al
    Lipid-associated macrophages' promotion of fibrosis resolution during MASH regression requires TREM2.
    Proc Natl Acad Sci U S A. 2024;121:e2405746121.
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    April 2024
  13. SHERMAN DJ, Liu L, Mamrosh JL, Xie J, et al
    The fatty liver disease-causing protein PNPLA3-I148M alters lipid droplet-Golgi dynamics.
    Proc Natl Acad Sci U S A. 2024;121:e2318619121.
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  14. BAKIRI L, Hasenfuss SC, Guio-Carrion A, Thomsen MK, et al
    Liver cancer development driven by the AP-1/c-Jun~Fra-2 dimer through c-Myc.
    Proc Natl Acad Sci U S A. 2024;121:e2404188121.
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  15. GU L, Du Y, Chen J, Hasan MN, et al
    Cullin 3 RING E3 ligase inactivation causes NRF2-dependent NADH reductive stress, hepatic lipodystrophy, and systemic insulin resistance.
    Proc Natl Acad Sci U S A. 2024;121:e2320934121.
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    February 2024
  16. DAS A, Cheng H, Wang Y, Kinch LN, et al
    The ubiquitin E3 ligase BFAR promotes degradation of PNPLA3.
    Proc Natl Acad Sci U S A. 2024;121:e2312291121.
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    January 2024
  17. HULLAHALLI K, Dailey KG, Hasegawa Y, Johnson WE, et al
    Reverse transcriptase inhibitors prevent liver abscess formation during Escherichia coli bloodstream infection.
    Proc Natl Acad Sci U S A. 2024;121:e2319162121.
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    December 2023
  18. SAKUMA I, Gaspar RC, Luukkonen PK, Kahn M, et al
    Lysophosphatidic acid triggers inflammation in the liver and white adipose tissue in rat models of 1-acyl-sn-glycerol-3-phosphate acyltransferase 2 deficiency and overnutrition.
    Proc Natl Acad Sci U S A. 2023;120:e2312666120.
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  19. HULLAHALLI K, Dailey KG, Hasegawa Y, Torres E, et al
    Genetic and immune determinants of E. coli liver abscess formation.
    Proc Natl Acad Sci U S A. 2023;120:e2310053120.
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    November 2023
  20. YUAN D, Hu J, Ju X, Putz EM, et al
    NMDAR antagonists suppress tumor progression by regulating tumor-associated macrophages.
    Proc Natl Acad Sci U S A. 2023;120:e2302126120.
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