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    August 2021
  1. QIU P, Hou W, Wang H, Lei KKW, et al
    Sirt1 deficiency upregulates glutathione metabolism to prevent hepatocellular carcinoma initiation in mice.
    Oncogene. 2021 Aug 25. pii: 10.1038/s41388-021-01993.
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    July 2021
  2. LIU Z, Wang A, Pu Y, Li Z, et al
    Genomic and transcriptomic profiling of hepatoid adenocarcinoma of the stomach.
    Oncogene. 2021 Jul 30. pii: 10.1038/s41388-021-01976.
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  3. ZHANG Y, Yan Q, Gong L, Xu H, et al
    Correction: C-terminal truncated HBx initiates hepatocarcinogenesis by downregulating TXNIP and reprogramming glucose metabolism.
    Oncogene. 2021 Jul 26. pii: 10.1038/s41388-021-01942.
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  4. BRAHMA MK, Gilglioni EH, Zhou L, Trepo E, et al
    Oxidative stress in obesity-associated hepatocellular carcinoma: sources, signaling and therapeutic challenges.
    Oncogene. 2021 Jul 21. pii: 10.1038/s41388-021-01950.
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  5. ZHANG EB, Zhang X, Wang K, Zhang F, et al
    Antifungal agent Terbinafine restrains tumor growth in preclinical models of hepatocellular carcinoma via AMPK-mTOR axis.
    Oncogene. 2021 Jul 10. pii: 10.1038/s41388-021-01934.
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    June 2021
  6. LIN YH, Wu MH, Liu YC, Lyu PC, et al
    LINC01348 suppresses hepatocellular carcinoma metastasis through inhibition of SF3B3-mediated EZH2 pre-mRNA splicing.
    Oncogene. 2021 Jun 17. pii: 10.1038/s41388-021-01905.
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  7. WANG S, Cao K, Liao Y, Zhang W, et al
    CDCA2 protects against oxidative stress by promoting BRCA1-NRF2 signaling in hepatocellular carcinoma.
    Oncogene. 2021 Jun 8. pii: 10.1038/s41388-021-01855.
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  8. WANG X, Dong J, Li X, Cheng Z, et al
    CPSF4 regulates circRNA formation and microRNA mediated gene silencing in hepatocellular carcinoma.
    Oncogene. 2021 Jun 8. pii: 10.1038/s41388-021-01867.
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  9. SHEN M, Zhang R, Jia W, Zhu Z, et al
    Nuclear scaffold protein p54(nrb)/NONO facilitates the hypoxia-enhanced progression of hepatocellular carcinoma.
    Oncogene. 2021 Jun 2. pii: 10.1038/s41388-021-01848.
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    May 2021
  10. CAROTTI S, Zingariello M, Francesconi M, D'Andrea L, et al
    Fragile X mental retardation protein in intrahepatic cholangiocarcinoma: regulating the cancer cell behavior plasticity at the leading edge.
    Oncogene. 2021 May 20. pii: 10.1038/s41388-021-01824.
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    April 2021
  11. CHEN S, Du Y, Xu B, Li Q, et al
    Vaccinia-related kinase 2 blunts sorafenib's efficacy against hepatocellular carcinoma by disturbing the apoptosis-autophagy balance.
    Oncogene. 2021 Apr 19. pii: 10.1038/s41388-021-01780.
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  12. CHEN K, Hou Y, Liao R, Li Y, et al
    LncRNA SNHG6 promotes G1/S-phase transition in hepatocellular carcinoma by impairing miR-204-5p-mediated inhibition of E2F1.
    Oncogene. 2021 Apr 6. pii: 10.1038/s41388-021-01671.
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    March 2021
  13. ZHANG G, Yang Y, Hu H, Liu K, et al
    Energy stress-induced linc01564 activates the serine synthesis pathway and facilitates hepatocellular carcinogenesis.
    Oncogene. 2021 Mar 19. pii: 10.1038/s41388-021-01749.
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  14. JING CY, Fu YP, Zhou C, Zhang MX, et al
    Hepatic stellate cells promote intrahepatic cholangiocarcinoma progression via NR4A2/osteopontin/Wnt signaling axis.
    Oncogene. 2021 Mar 19. pii: 10.1038/s41388-021-01705.
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  15. PAN Z, Liu C, Zhi Y, Xie Z, et al
    LIMK1 nuclear translocation promotes hepatocellular carcinoma progression by increasing p-ERK nuclear shuttling and by activating c-Myc signalling upon EGF stimulation.
    Oncogene. 2021 Mar 8. pii: 10.1038/s41388-021-01736.
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  16. ALASADI A, Cao B, Guo J, Tao H, et al
    Mitochondrial uncoupler MB1-47 is efficacious in treating hepatic metastasis of pancreatic cancer in murine tumor transplantation models.
    Oncogene. 2021 Mar 1. pii: 10.1038/s41388-021-01688.
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    February 2021
  17. LUO JH, Liu S, Tao J, Ren BG, et al
    Pten-NOLC1 fusion promotes cancers involving MET and EGFR signalings.
    Oncogene. 2021;40:1064-1076.
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    January 2021
  18. LU Y, Li X, Liu H, Xue J, et al
    beta-Trcp and CK1delta-mediated degradation of LZTS2 activates PI3K/AKT signaling to drive tumorigenesis and metastasis in hepatocellular carcinoma.
    Oncogene. 2021 Jan 8. pii: 10.1038/s41388-020-01596.
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    December 2020
  19. ZHANG Y, Yan Q, Gong L, Xu H, et al
    C-terminal truncated HBx initiates hepatocarcinogenesis by downregulating TXNIP and reprogramming glucose metabolism.
    Oncogene. 2020 Dec 15. pii: 10.1038/s41388-020-01593.
    >> Share

    November 2020
  20. YAO L, Xuan Y, Zhang H, Yang B, et al
    Reciprocal REGgamma-mTORC1 regulation promotes glycolytic metabolism in hepatocellular carcinoma.
    Oncogene. 2020 Nov 23. pii: 10.1038/s41388-020-01558.
    >> Share

  21. YU J, Wang N, Gong Z, Liu L, et al
    Cytochrome P450 1A2 overcomes nuclear factor kappa B-mediated sorafenib resistance in hepatocellular carcinoma.
    Oncogene. 2020 Nov 12. pii: 10.1038/s41388-020-01545.
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    October 2020
  22. LIU C, Zhou X, Long Q, Zeng H, et al
    Small extracellular vesicles containing miR-30a-3p attenuate the migration and invasion of hepatocellular carcinoma by targeting SNAP23 gene.
    Oncogene. 2020 Oct 27. pii: 10.1038/s41388-020-01521.
    >> Share

  23. NIMMAKAYALA RK, Leon F, Rachagani S, Rauth S, et al
    Metabolic programming of distinct cancer stem cells promotes metastasis of pancreatic ductal adenocarcinoma.
    Oncogene. 2020 Oct 27. pii: 10.1038/s41388-020-01518.
    >> Share

  24. CHEN J, Xuan Z, Song W, Han W, et al
    EAG1 enhances hepatocellular carcinoma proliferation by modulating SKP2 and metastasis through pseudopod formation.
    Oncogene. 2020 Oct 24. pii: 10.1038/s41388-020-01522.
    >> Share

  25. VON FELDEN J, Craig AJ, Garcia-Lezana T, Labgaa I, et al
    Mutations in circulating tumor DNA predict primary resistance to systemic therapies in advanced hepatocellular carcinoma.
    Oncogene. 2020 Oct 23. pii: 10.1038/s41388-020-01519.
    >> Share

  26. GAMAEV L, Mizrahi L, Friehmann T, Rosenberg N, et al
    The pro-oncogenic effect of the lncRNA H19 in the development of chronic inflammation-mediated hepatocellular carcinoma.
    Oncogene. 2020 Oct 22. pii: 10.1038/s41388-020-01513.
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  27. YAN Y, Huang P, Mao K, He C, et al
    Anti-oncogene PTPN13 inactivation by hepatitis B virus X protein counteracts IGF2BP1 to promote hepatocellular carcinoma progression.
    Oncogene. 2020 Oct 13. pii: 10.1038/s41388-020-01498.
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  28. HE Q, Lin Z, Wang Z, Huang W, et al
    SIX4 promotes hepatocellular carcinoma metastasis through upregulating YAP1 and c-MET.
    Oncogene. 2020 Oct 12. pii: 10.1038/s41388-020-01500.
    >> Share

    September 2020
  29. SUN Z, Xue S, Zhang M, Xu H, et al
    Aberrant NSUN2-mediated m(5)C modification of H19 lncRNA is associated with poor differentiation of hepatocellular carcinoma.
    Oncogene. 2020 Sep 25. pii: 10.1038/s41388-020-01475.
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  30. YANG B, Feng X, Liu H, Tong R, et al
    High-metastatic cancer cells derived exosomal miR92a-3p promotes epithelial-mesenchymal transition and metastasis of low-metastatic cancer cells by regulating PTEN/Akt pathway in hepatocellular carcinoma.
    Oncogene. 2020 Sep 11. pii: 10.1038/s41388-020-01450.
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  31. ZHOU Q, Huang T, Jiang Z, Ge C, et al
    Correction: Upregulation of SNX5 predicts poor prognosis and promotes hepatocellular carcinoma progression by modulating the EGFR-ERK1/2 signaling pathway.
    Oncogene. 2020 Sep 7. pii: 10.1038/s41388-020-01440.
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    August 2020
  32. WU D, Wang Y, Yang G, Zhang S, et al
    A novel mitochondrial amidoxime reducing component 2 is a favorable indicator of cancer and suppresses the progression of hepatocellular carcinoma by regulating the expression of p27.
    Oncogene. 2020 Aug 18. pii: 10.1038/s41388-020-01417.
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  33. BARTOLOME RA, Pintado-Berninches L, Jaen M, de Los Rios V, et al
    SOSTDC1 promotes invasion and liver metastasis in colorectal cancer via interaction with ALCAM/CD166.
    Oncogene. 2020 Aug 15. pii: 10.1038/s41388-020-01419.
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    July 2020
  34. SHI X, Liu TT, Yu XN, Balakrishnan A, et al
    microRNA-93-5p promotes hepatocellular carcinoma progression via a microRNA-93-5p/MAP3K2/c-Jun positive feedback circuit.
    Oncogene. 2020 Jul 27. pii: 10.1038/s41388-020-01401.
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  35. FENG H, Liu J, Qiu Y, Liu Y, et al
    RNA-binding motif protein 43 (RBM43) suppresses hepatocellular carcinoma progression through modulation of cyclin B1 expression.
    Oncogene. 2020 Jul 6. pii: 10.1038/s41388-020-1380.
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    May 2020
  36. TSAI CN, Yu SC, Lee CW, Pang JS, et al
    SOX4 activates CXCL12 in hepatocellular carcinoma cells to modulate endothelial cell migration and angiogenesis in vivo.
    Oncogene. 2020 May 13. pii: 10.1038/s41388-020-1319.
    >> Share

  37. HUANG WJ, Tian XP, Bi SX, Zhang SR, et al
    The beta-catenin/TCF-4-LINC01278-miR-1258-Smad2/3 axis promotes hepatocellular carcinoma metastasis.
    Oncogene. 2020 May 5. pii: 10.1038/s41388-020-1307.
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  38. ZHANG C, Huang S, Zhuang H, Ruan S, et al
    YTHDF2 promotes the liver cancer stem cell phenotype and cancer metastasis by regulating OCT4 expression via m6A RNA methylation.
    Oncogene. 2020 May 4. pii: 10.1038/s41388-020-1303.
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  39. WILLIAMS M, Liu X, Zhang Y, Reske J, et al
    NCOA5 deficiency promotes a unique liver protumorigenic microenvironment through p21(WAF1/CIP1) overexpression, which is reversed by metformin.
    Oncogene. 2020;39:3821-3836.
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    April 2020
  40. TIAN L, Yao K, Liu K, Han B, et al
    PLK1/NF-kappaB feedforward circuit antagonizes the mono-ADP-ribosyltransferase activity of PARP10 and facilitates HCC progression.
    Oncogene. 2020;39:3145-3162.
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    March 2020
  41. LI W, Dai Y, Shi B, Yue F, et al
    LRPPRC sustains Yap-P27-mediated cell ploidy and P62-HDAC6-mediated autophagy maturation and suppresses genome instability and hepatocellular carcinomas.
    Oncogene. 2020 Mar 16. pii: 10.1038/s41388-020-1257.
    >> Share

  42. HUANG P, Xu Q, Yan Y, Lu Y, et al
    HBx/ERalpha complex-mediated LINC01352 downregulation promotes HBV-related hepatocellular carcinoma via the miR-135b-APC axis.
    Oncogene. 2020 Mar 10. pii: 10.1038/s41388-020-1254.
    >> Share

  43. PINATO DJ, Guerra N, Fessas P, Murphy R, et al
    Immune-based therapies for hepatocellular carcinoma.
    Oncogene. 2020 Mar 10. pii: 10.1038/s41388-020-1249.
    >> Share

  44. HSU BE, Roy J, Mouhanna J, Rayes RF, et al
    C3a elicits unique migratory responses in immature low-density neutrophils.
    Oncogene. 2020;39:2612-2623.
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  45. XIAO Y, Liu G, Sun Y, Gao Y, et al
    Targeting the estrogen receptor alpha (ERalpha)-mediated circ-SMG1.72/miR-141-3p/Gelsolin signaling to better suppress the HCC cell invasion.
    Oncogene. 2020;39:2493-2508.
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  46. SAKSOUK N, Hajdari S, Perez Y, Pratlong M, et al
    The mouse HP1 proteins are essential for preventing liver tumorigenesis.
    Oncogene. 2020;39:2676-2691.
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    February 2020
  47. ZHANG G, Tang X, Liang L, Zhang W, et al
    DNA and RNA sequencing identified a novel oncogene VPS35 in liver hepatocellular carcinoma.
    Oncogene. 2020 Feb 19. pii: 10.1038/s41388-020-1215.
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  48. LUIKEN S, Fraas A, Bieg M, Sugiyanto R, et al
    NOTCH target gene HES5 mediates oncogenic and tumor suppressive functions in hepatocarcinogenesis.
    Oncogene. 2020 Feb 13. pii: 10.1038/s41388-020-1198.
    >> Share

  49. CHEN P, Duan X, Li X, Li J, et al
    HIPK2 suppresses tumor growth and progression of hepatocellular carcinoma through promoting the degradation of HIF-1alpha.
    Oncogene. 2020 Feb 7. pii: 10.1038/s41388-020-1190.
    >> Share

  50. GUAN C, He L, Chang Z, Gu X, et al
    Correction: ZNF774 is a potent suppressor of hepatocarcinogenesis through dampening the NOTCH2 signaling.
    Oncogene. 2020 Feb 3. pii: 10.1038/s41388-020-1180.
    >> Share

  51. DAI K, Tanaka M, Kamiyoshi A, Sakurai T, et al
    Deficiency of the adrenomedullin-RAMP3 system suppresses metastasis through the modification of cancer-associated fibroblasts.
    Oncogene. 2020;39:1914-1930.
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    January 2020
  52. GU L, Zhu Y, Lin X, Tan X, et al
    Stabilization of FASN by ACAT1-mediated GNPAT acetylation promotes lipid metabolism and hepatocarcinogenesis.
    Oncogene. 2020 Jan 23. pii: 10.1038/s41388-020-1156.
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  53. OUAHOUD S, Voorneveld PW, van der Burg LRA, de Jonge-Muller ESM, et al
    Bidirectional tumor/stroma crosstalk promotes metastasis in mesenchymal colorectal cancer.
    Oncogene. 2020 Jan 23. pii: 10.1038/s41388-020-1157.
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  54. GUAN YF, Huang QL, Ai YL, Chen QT, et al
    Nur77-activated lncRNA WFDC21P attenuates hepatocarcinogenesis via modulating glycolysis.
    Oncogene. 2020 Jan 20. pii: 10.1038/s41388-020-1158.
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    December 2019
  55. ZHOU Q, Huang T, Jiang Z, Ge C, et al
    Upregulation of SNX5 predicts poor prognosis and promotes hepatocellular carcinoma progression by modulating the EGFR-ERK1/2 signaling pathway.
    Oncogene. 2019 Dec 9. pii: 10.1038/s41388-019-1131.
    >> Share

    November 2019
  56. ZHONG R, Tian J, Fu M, Ma S, et al
    LINC01149 variant modulates MICA expression that facilitates hepatitis B virus spontaneous recovery but increases hepatocellular carcinoma risk.
    Oncogene. 2019 Nov 21. pii: 10.1038/s41388-019-1117.
    >> Share

  57. DONG KS, Chen Y, Yang G, Liao ZB, et al
    TGF-beta1 accelerates the hepatitis B virus X-induced malignant transformation of hepatic progenitor cells by upregulating miR-199a-3p.
    Oncogene. 2019 Nov 18. pii: 10.1038/s41388-019-1107.
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  58. THOMSEN MK, Skouboe MK, Boularan C, Vernejoul F, et al
    The cGAS-STING pathway is a therapeutic target in a preclinical model of hepatocellular carcinoma.
    Oncogene. 2019 Nov 18. pii: 10.1038/s41388-019-1108.
    >> Share

  59. ZHAO J, Hou Y, Yin C, Hu J, et al
    Upregulation of histamine receptor H1 promotes tumor progression and contributes to poor prognosis in hepatocellular carcinoma.
    Oncogene. 2019 Nov 18. pii: 10.1038/s41388-019-1093.
    >> Share

  60. ELIAS D, Vever H, Laenkholm AV, Gjerstorff MF, et al
    Correction: VersicanV1 promotes proliferation and metastasis of hepatocellular carcinoma through the activation of EGFR-PI3K-AKT pathway.
    Oncogene. 2019 Nov 11. pii: 10.1038/s41388-019-1096.
    >> Share

  61. ZHANGYUAN G, Wang F, Zhang H, Jiang R, et al
    Correction: VersicanV1 promotes proliferation and metastasis of hepatocellular carcinoma through the activation of EGFR-PI3K-AKT pathway.
    Oncogene. 2019 Nov 7. pii: 10.1038/s41388-019-1095.
    >> Share

    October 2019
  62. XU G, Feng D, Yao Y, Li P, et al
    Listeria-based hepatocellular carcinoma vaccine facilitates anti-PD-1 therapy by regulating macrophage polarization.
    Oncogene. 2019 Oct 28. pii: 10.1038/s41388-019-1072.
    >> Share

  63. GUAN C, He L, Chang Z, Gu X, et al
    ZNF774 is a potent suppressor of hepatocarcinogenesis through dampening the NOTCH2 signaling.
    Oncogene. 2019 Oct 28. pii: 10.1038/s41388-019-1075.
    >> Share

  64. ZHANGYUAN G, Wang F, Zhang H, Jiang R, et al
    VersicanV1 promotes proliferation and metastasis of hepatocellular carcinoma through the activation of EGFR-PI3K-AKT pathway.
    Oncogene. 2019 Oct 11. pii: 10.1038/s41388-019-1052.
    >> Share

  65. LI B, Chen Y, Wang F, Guo J, et al
    Bmi1 drives hepatocarcinogenesis by repressing the TGFbeta2/SMAD signalling axis.
    Oncogene. 2019 Oct 7. pii: 10.1038/s41388-019-1043.
    >> Share

    September 2019
  66. LI X, Ding J, Wang X, Cheng Z, et al
    NUDT21 regulates circRNA cyclization and ceRNA crosstalk in hepatocellular carcinoma.
    Oncogene. 2019 Sep 30. pii: 10.1038/s41388-019-1030.
    >> Share

  67. HSU YL, Huang MS, Hung JY, Chang WA, et al
    Bone-marrow-derived cell-released extracellular vesicle miR-92a regulates hepatic pre-metastatic niche in lung cancer.
    Oncogene. 2019 Sep 26. pii: 10.1038/s41388-019-1024.
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    August 2019
  68. YUAN YM, Ma N, Zhang EB, Chen TW, et al
    BMP10 suppresses hepatocellular carcinoma progression via PTPRS-STAT3 axis.
    Oncogene. 2019 Aug 15. pii: 10.1038/s41388-019-0943.
    >> Share

  69. SHANKARAIAH RC, Callegari E, Guerriero P, Rimessi A, et al
    Metformin prevents liver tumourigenesis by attenuating fibrosis in a transgenic mouse model of hepatocellular carcinoma.
    Oncogene. 2019 Aug 13. pii: 10.1038/s41388-019-0942.
    >> Share

  70. WANG J, Li N, Huang ZB, Fu S, et al
    HBx regulates transcription factor PAX8 stabilization to promote the progression of hepatocellular carcinoma.
    Oncogene. 2019 Aug 7. pii: 10.1038/s41388-019-0907.
    >> Share

    July 2019
  71. CHU TH, Huang ST, Yang SF, Li CJ, et al
    Hepatoma-derived growth factor participates in Helicobacter Pylori-induced neutrophils recruitment, gastritis and gastric carcinogenesis.
    Oncogene. 2019 Jul 22. pii: 10.1038/s41388-019-0886.
    >> Share

  72. WEI T, Weiler SME, Toth M, Sticht C, et al
    YAP-dependent induction of UHMK1 supports nuclear enrichment of the oncogene MYBL2 and proliferation in liver cancer cells.
    Oncogene. 2019;38:5541-5550.
    >> Share

    June 2019
  73. BAO D, Zhao J, Zhou X, Yang Q, et al
    Mitochondrial fission-induced mtDNA stress promotes tumor-associated macrophage infiltration and HCC progression.
    Oncogene. 2019;38:5007-5020.
    >> Share

    May 2019
  74. MARCHAND B, Pitarresi JR, Reichert M, Suzuki K, et al
    PRRX1 isoforms cooperate with FOXM1 to regulate the DNA damage response in pancreatic cancer cells.
    Oncogene. 2019;38:4325-4339.
    >> Share

    April 2019
  75. CUI Y, Wu X, Lin C, Zhang X, et al
    AKIP1 promotes early recurrence of hepatocellular carcinoma through activating the Wnt/beta-catenin/CBP signaling pathway.
    Oncogene. 2019 Apr 1. pii: 10.1038/s41388-019-0807.
    >> Share

    March 2019
  76. YANG H, Zhu R, Zhao X, Liu L, et al
    Sirtuin-mediated deacetylation of hnRNP A1 suppresses glycolysis and growth in hepatocellular carcinoma.
    Oncogene. 2019 Mar 11. pii: 10.1038/s41388-019-0764.
    >> Share

  77. WANG Y, Xie BH, Lin WH, Huang YH, et al
    Amplification of SMYD3 promotes tumorigenicity and intrahepatic metastasis of hepatocellular carcinoma via upregulation of CDK2 and MMP2.
    Oncogene. 2019 Mar 6. pii: 10.1038/s41388-019-0766.
    >> Share

    February 2019
  78. DANG S, Zhou J, Chen Y, Chen P, et al
    Dynamic expression of ZNF382 and its tumor-suppressor role in hepatitis B virus-related hepatocellular carcinogenesis.
    Oncogene. 2019 Feb 25. pii: 10.1038/s41388-019-0759.
    >> Share

  79. TORRES-HERNANDEZ A, Wang W, Nikiforov Y, Tejada K, et al
    Targeting SYK signaling in myeloid cells protects against liver fibrosis and hepatocarcinogenesis.
    Oncogene. 2019 Feb 11. pii: 10.1038/s41388-019-0734.
    >> Share

    January 2019
  80. FANG S, Liu M, Li L, Zhang FF, et al
    Lymphoid enhancer-binding factor-1 promotes stemness and poor differentiation of hepatocellular carcinoma by directly activating the NOTCH pathway.
    Oncogene. 2019 Jan 29. pii: 10.1038/s41388-019-0704.
    >> Share

  81. HUANG JF, Jiang HY, Cai H, Liu Y, et al
    Genome-wide screening identifies oncofetal lncRNA Ptn-dt promoting the proliferation of hepatocellular carcinoma cells by regulating the Ptn receptor.
    Oncogene. 2019 Jan 14. pii: 10.1038/s41388-018-0643.
    >> Share

  82. ZHAO X, Reebye V, Hitchen P, Fan J, et al
    Mechanisms involved in the activation of C/EBPalpha by small activating RNA in hepatocellular carcinoma.
    Oncogene. 2019 Jan 14. pii: 10.1038/s41388-018-0665.
    >> Share

  83. GUHA P, Gardell J, Darpolor J, Cunetta M, et al
    STAT3 inhibition induces Bax-dependent apoptosis in liver tumor myeloid-derived suppressor cells.
    Oncogene. 2019;38:533-548.
    >> Share

  84. WANG LT, Wang SN, Chiou SS, Liu KY, et al
    TIP60-dependent acetylation of the SPZ1-TWIST complex promotes epithelial-mesenchymal transition and metastasis in liver cancer.
    Oncogene. 2019;38:518-532.
    >> Share

    December 2018
  85. CORTES E, Lachowski D, Rice A, Thorpe SD, et al
    Tamoxifen mechanically deactivates hepatic stellate cells via the G protein-coupled estrogen receptor.
    Oncogene. 2018 Dec 21. pii: 10.1038/s41388-018-0631.
    >> Share

  86. LAOUIREM S, Sannier A, Norkowski E, Cauchy F, et al
    Endothelial fatty liver binding protein 4: a new targetable mediator in hepatocellular carcinoma related to metabolic syndrome.
    Oncogene. 2018 Dec 21. pii: 10.1038/s41388-018-0597.
    >> Share

  87. ZHANG H, Deng T, Ge S, Liu Y, et al
    Exosome circRNA secreted from adipocytes promotes the growth of hepatocellular carcinoma by targeting deubiquitination-related USP7.
    Oncogene. 2018 Dec 13. pii: 10.1038/s41388-018-0619.
    >> Share

  88. AHODANTIN J, Bou-Nader M, Cordier C, Megret J, et al
    Hepatitis B virus X protein promotes DNA damage propagation through disruption of liver polyploidization and enhances hepatocellular carcinoma initiation.
    Oncogene. 2018 Dec 11. pii: 10.1038/s41388-018-0607.
    >> Share

    November 2018
  89. CHONG YC, Lim TE, Fu Y, Shin EM, et al
    Indian Hedgehog links obesity to development of hepatocellular carcinoma.
    Oncogene. 2018 Nov 23. pii: 10.1038/s41388-018-0585.
    >> Share

    October 2018
  90. WEN Y, Zhou X, Lu M, He M, et al
    Bclaf1 promotes angiogenesis by regulating HIF-1alpha transcription in hepatocellular carcinoma.
    Oncogene. 2018 Oct 26. pii: 10.1038/s41388-018-0552.
    >> Share

  91. DI LEO L, Vegliante R, Ciccarone F, Salvatori I, et al
    Forcing ATGL expression in hepatocarcinoma cells imposes glycolytic rewiring through PPAR-alpha/p300-mediated acetylation of p53.
    Oncogene. 2018 Oct 26. pii: 10.1038/s41388-018-0545.
    >> Share

    September 2018
  92. DOU C, Zhou Z, Xu Q, Liu Z, et al
    Hypoxia-induced TUFT1 promotes the growth and metastasis of hepatocellular carcinoma by activating the Ca(2+)/PI3K/AKT pathway.
    Oncogene. 2018 Sep 24. pii: 10.1038/s41388-018-0505.
    >> Share

    August 2018
  93. HAN J, Wang F, Lan Y, Wang J, et al
    KIFC1 regulated by miR-532-3p promotes epithelial-to-mesenchymal transition and metastasis of hepatocellular carcinoma via gankyrin/AKT signaling.
    Oncogene. 2018 Aug 16. pii: 10.1038/s41388-018-0440.
    >> Share

  94. LAI CY, Liu H, Tin KX, Huang Y, et al
    Identification of UAP1L1 as a critical factor for protein O-GlcNAcylation and cell proliferation in human hepatoma cells.
    Oncogene. 2018 Aug 10. pii: 10.1038/s41388-018-0442.
    >> Share

  95. TOSHIYAMA R, Konno M, Eguchi H, Takemoto H, et al
    Poly(ethylene glycol)-poly(lysine) block copolymer-ubenimex conjugate targets aminopeptidase N and exerts an antitumor effect in hepatocellular carcinoma stem cells.
    Oncogene. 2018 Aug 8. pii: 10.1038/s41388-018-0406.
    >> Share

  96. MENG J, Chen S, Lei YY, Han JX, et al
    Hsp90beta promotes aggressive vasculogenic mimicry via epithelial-mesenchymal transition in hepatocellular carcinoma.
    Oncogene. 2018 Aug 7. pii: 10.1038/s41388-018-0428.
    >> Share

  97. YANG X, Qu S, Wang L, Zhang H, et al
    PTBP3 splicing factor promotes hepatocellular carcinoma by destroying the splicing balance of NEAT1 and pre-miR-612.
    Oncogene. 2018 Aug 1. pii: 10.1038/s41388-018-0416.
    >> Share

  98. YOON S, Lee EJ, Choi JH, Chung T, et al
    Recapitulation of pharmacogenomic data reveals that invalidation of SULF2 enhance sorafenib susceptibility in liver cancer.
    Oncogene. 2018;37:4443-4454.
    >> Share

    July 2018
  99. YANG Y, Wu XQ, Li WX, Huang HM, et al
    PSTPIP2 connects DNA methylation to macrophage polarization in CCL4-induced mouse model of hepatic fibrosis.
    Oncogene. 2018 Jul 11. pii: 10.1038/s41388-018-0383.
    >> Share

  100. VANIOTIS G, Rayes RF, Qi S, Milette S, et al
    Collagen IV-conveyed signals can regulate chemokine production and promote liver metastasis.
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    June 2018
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    SYT7 acts as a driver of hepatic metastasis formation of gastric cancer cells.
    Oncogene. 2018 Jun 1. pii: 10.1038/s41388-018-0335.
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  102. REEBYE V, Huang KW, Lin V, Jarvis S, et al
    Gene activation of CEBPA using saRNA: preclinical studies of the first in human saRNA drug candidate for liver cancer.
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  103. CHEN Z, Gao Y, Yao L, Liu Y, et al
    LncFZD6 initiates Wnt/beta-catenin and liver TIC self-renewal through BRG1-mediated FZD6 transcriptional activation.
    Oncogene. 2018;37:3098-3112.
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    May 2018
  104. LIU H, Chen W, Zhi X, Chen EJ, et al
    Tumor-derived exosomes promote tumor self-seeding in hepatocellular carcinoma by transferring miRNA-25-5p to enhance cell motility.
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  105. TAN S, Li H, Zhang W, Shao Y, et al
    NUDT21 negatively regulates PSMB2 and CXXC5 by alternative polyadenylation and contributes to hepatocellular carcinoma suppression.
    Oncogene. 2018 May 21. pii: 10.1038/s41388-018-0280.
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  106. PINATO DJ
    Circulating-free tumour DNA and the promise of disease phenotyping in hepatocellular carcinoma.
    Oncogene. 2018 May 14. pii: 10.1038/s41388-018-0262.
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  107. ZHAO Y, Hu X, Wei L, Song D, et al
    PARP10 suppresses tumor metastasis through regulation of Aurora A activity.
    Oncogene. 2018;37:2921-2935.
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  108. JIANG Y, Xu E, Zhang J, Chen M, et al
    The Rbm38-p63 feedback loop is critical for tumor suppression and longevity.
    Oncogene. 2018;37:2863-2872.
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  109. ZHANG H, Song Y, Yang H, Liu Z, et al
    Tumor cell-intrinsic Tim-3 promotes liver cancer via NF-kappaB/IL-6/STAT3 axis.
    Oncogene. 2018;37:2456-2468.
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    April 2018
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    A pilot study of ultra-deep targeted sequencing of plasma DNA identifies driver mutations in hepatocellular carcinoma.
    Oncogene. 2018 Apr 9. pii: 10.1038/s41388-018-0206.
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    March 2018
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    Stress-induced phosphoprotein 1 mediates hepatocellular carcinoma metastasis after insufficient radiofrequency ablation.
    Oncogene. 2018 Mar 21. pii: 10.1038/s41388-018-0169.
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  112. CHU PC, Lin PC, Wu HY, Lin KT, et al
    Mutant KRAS promotes liver metastasis of colorectal cancer, in part, by upregulating the MEK-Sp1-DNMT1-miR-137-YB-1-IGF-IR signaling pathway.
    Oncogene. 2018 Mar 21. pii: 10.1038/s41388-018-0222.
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  113. LIU X, Bi L, Wang Q, Wen M, et al
    miR-1204 targets VDR to promotes epithelial-mesenchymal transition and metastasis in breast cancer.
    Oncogene. 2018 Mar 20. pii: 10.1038/s41388-018-0215.
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  114. EHEDEGO H, Mohs A, Jansen B, Hiththetiya K, et al
    Loss of Cyclin E1 attenuates hepatitis and hepatocarcinogenesis in a mouse model of chronic liver injury.
    Oncogene. 2018 Mar 19. pii: 10.1038/s41388-018-0181.
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  115. WANG J, Dong M, Xu Z, Song X, et al
    Notch2 controls hepatocyte-derived cholangiocarcinoma formation in mice.
    Oncogene. 2018 Mar 16. pii: 10.1038/s41388-018-0188.
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  116. DONG L, Yu L, Bai C, Liu L, et al
    USP27-mediated Cyclin E stabilization drives cell cycle progression and hepatocellular tumorigenesis.
    Oncogene. 2018 Mar 2. pii: 10.1038/s41388-018-0137.
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  117. IM JY, Kim BK, Lee JY, Park SH, et al
    DDIAS suppresses TRAIL-mediated apoptosis by inhibiting DISC formation and destabilizing caspase-8 in cancer cells.
    Oncogene. 2018;37:1251-1262.
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  118. YANG JB, Zhao ZB, Liu QZ, Hu TD, et al
    FoxO1 is a regulator of MHC-II expression and anti-tumor effect of tumor-associated macrophages.
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    February 2018
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    Upregulation of the ALDOA/DNA-PK/p53 pathway by dietary restriction suppresses tumor growth.
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  120. DI RUOCCO F, Basso V, Rivoire M, Mehlen P, et al
    Alu RNA accumulation induces epithelial-to-mesenchymal transition by modulating miR-566 and is associated with cancer progression.
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    January 2018
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    miR-139-5p inhibits aerobic glycolysis, cell proliferation, migration, and invasion in hepatocellular carcinoma via a reciprocal regulatory interaction with ETS1.
    Oncogene. 2018 Jan 16. pii: 10.1038/s41388-017-0057.
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  122. LIU MX, Jin L, Sun SJ, Liu P, et al
    Metabolic reprogramming by PCK1 promotes TCA cataplerosis, oxidative stress and apoptosis in liver cancer cells and suppresses hepatocellular carcinoma.
    Oncogene. 2018 Jan 16. pii: 10.1038/s41388-017-0070.
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  123. MARTINEZ-ORDONEZ A, Seoane S, Cabezas P, Eiro N, et al
    Breast cancer metastasis to liver and lung is facilitated by Pit-1-CXCL12-CXCR4 axis.
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    December 2017
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    Ribosomal protein S15a promotes tumor angiogenesis via enhancing Wnt/beta-catenin-induced FGF18 expression in hepatocellular carcinoma.
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  125. BLOMME A, Van Simaeys G, Doumont G, Costanza B, et al
    Murine stroma adopts a human-like metabolic phenotype in the PDX model of colorectal cancer and liver metastases.
    Oncogene. 2017 Dec 15. pii: 10.1038/s41388-017-0018.
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    November 2017
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    Reticulocalbin-2 enhances hepatocellular carcinoma proliferation via modulating the EGFR-ERK pathway.
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  127. NAKATSUKA T, Tateishi K, Kudo Y, Yamamoto K, et al
    Impact of histone demethylase KDM3A-dependent AP-1 transactivity on hepatotumorigenesis induced by PI3K activation.
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    October 2017
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    Wnt/beta-catenin activation and macrophage induction during liver cancer development following steatosis.
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  129. REN T, Zhang H, Wang J, Zhu J, et al
    MCU-dependent mitochondrial Ca2+ inhibits NAD+/SIRT3/SOD2 pathway to promote ROS production and metastasis of HCC cells.
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  130. NAKAYAMA M, Sakai E, Echizen K, Yamada Y, et al
    Intestinal cancer progression by mutant p53 through the acquisition of invasiveness associated with complex glandular formation.
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  131. GUO P, Ma X, Zhao W, Huai W, et al
    TRIM31 is upregulated in hepatocellular carcinoma and promotes disease progression by inducing ubiquitination of TSC1-TSC2 complex.
    Oncogene. 2017 Oct 2. doi: 10.1038/onc.2017.
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    September 2017
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    Ribosomal proteins: insight into molecular roles and functions in hepatocellular carcinoma.
    Oncogene. 2017 Sep 25. doi: 10.1038/onc.2017.
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  133. TRAN DDH, Kessler C, Niehus SE, Mahnkopf M, et al
    Myc target gene, long intergenic noncoding RNA, Linc00176 in hepatocellular carcinoma regulates cell cycle and cell survival by titrating tumor suppressor microRNAs.
    Oncogene. 2017 Sep 4. doi: 10.1038/onc.2017.
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    August 2017
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    Hepatitis B virus X protein promotes the development of liver fibrosis and hepatoma through downregulation of miR-30e targeting P4HA2 mRNA.
    Oncogene. 2017 Aug 28. doi: 10.1038/onc.2017.
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  135. LI J, Huang Q, Long X, Guo X, et al
    Mitochondrial elongation-mediated glucose metabolism reprogramming is essential for tumour cell survival during energy stress.
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  136. HAN H, Yang B, Wang W
    Angiomotin-like 2 interacts with and negatively regulates AKT.
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  137. LI J, Hu SB, Wang LY, Zhang X, et al
    Autophagy-dependent generation of Axin2+ cancer stem-like cells promotes hepatocarcinogenesis in liver cirrhosis.
    Oncogene. 2017 Aug 7. doi: 10.1038/onc.2017.
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  138. GOVAERE O, Petz M, Wouters J, Vandewynckel YP, et al
    The PDGFRalpha-laminin B1-keratin 19 cascade drives tumor progression at the invasive front of human hepatocellular carcinoma.
    Oncogene. 2017 Aug 7. doi: 10.1038/onc.2017.
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  139. WANG LT, Chiou SS, Chai CY, Hsi E, et al
    Transcription factor SPZ1 promotes TWIST-mediated epithelial-mesenchymal transition and oncogenesis in human liver cancer.
    Oncogene. 2017;36:4405-4414.
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    July 2017
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    Reticulocalbin-2 enhances hepatocellular carcinoma proliferation via modulating the EGFR-ERK pathway.
    Oncogene. 2017 Jul 24. doi: 10.1038/onc.2017.
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  141. FAN LC, Shiau CW, Tai WT, Hung MH, et al
    SHP-1 is a negative regulator of epithelial-mesenchymal transition in hepatocellular carcinoma.
    Oncogene. 2017 Jul 17. doi: 10.1038/onc.2017.
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    June 2017
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    LncRNA HULC triggers autophagy via stabilizing Sirt1 and attenuates the chemosensitivity of HCC cells.
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    May 2017
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    The NADPH oxidase NOX4 represses epithelial to amoeboid transition and efficient tumour dissemination.
    Oncogene. 2017;36:3002-3014.
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  144. CHI HC, Chen SL, Lin SL, Tsai CY, et al
    Thyroid hormone protects hepatocytes from HBx-induced carcinogenesis by enhancing mitochondrial turnover.
    Oncogene. 2017 May 15. doi: 10.1038/onc.2017.
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  145. XIN B, Yamamoto M, Fujii K, Ooshio T, et al
    Critical role of Myc activation in mouse hepatocarcinogenesis induced by the activation of AKT and RAS pathways.
    Oncogene. 2017 May 8. doi: 10.1038/onc.2017.
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    March 2017
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    Hepatic cyclooxygenase-2 overexpression induced spontaneous hepatocellular carcinoma formation in mice.
    Oncogene. 2017 Mar 27. doi: 10.1038/onc.2017.
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  147. HU X, Zhao Y, Wei L, Zhu B, et al
    CCDC178 promotes hepatocellular carcinoma metastasis through modulation of anoikis.
    Oncogene. 2017 Mar 20. doi: 10.1038/onc.2017.
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  148. ZHOU M, Mok MT, Sun H, Chan AW, et al
    The anti-diabetic drug exenatide, a glucagon-like peptide-1 receptor agonist, counteracts hepatocarcinogenesis through cAMP-PKA-EGFR-STAT3 axis.
    Oncogene. 2017 Mar 20. doi: 10.1038/onc.2017.
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    February 2017
  149. BATTISTELLI C, Cicchini C, Santangelo L, Tramontano A, et al
    The Snail repressor recruits EZH2 to specific genomic sites through the enrollment of the lncRNA HOTAIR in epithelial-to-mesenchymal transition.
    Oncogene. 2017;36:942-955.
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    September 2016
  150. HAASE G, Gavert N, Brabletz T, Ben-Ze'ev A, et al
    A point mutation in the extracellular domain of L1 blocks its capacity to confer metastasis in colon cancer cells via CD10.
    Oncogene. 2016 Sep 19. doi: 10.1038/onc.2016.
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