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Articles published in
Cancer Res
    October 2026
  1. GUO Z, Li Z, Lei T, Ren Y, et al
    ANXA1 Promotes Endoplasmic Reticulum-Mitochondria Calcium Coupling to Sustain Lenvatinib Resistance in Hepatocellular Carcinoma.
    Cancer Res. 2026 Oct 8. doi: 10.1158/0008-5472.CAN-26-2074.
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  2. YAO X, Wu B, Yang C, Lin Z, et al
    Placenta-Related PEG10 Inhibits mRNA Decay to Promote Glucose Metabolism and Tumor Progression in Hepatocellular Carcinoma.
    Cancer Res. 2026 Oct 2. doi: 10.1158/0008-5472.CAN-26-0490.
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    September 2026
  3. YAN Z, Wu D, Wu J, Shi C, et al
    MYC-Dependent rRNA Catabolism Stress Dictates Survival Heterogeneity of Hepatocellular Carcinoma Cells Under Glutamine Deprivation.
    Cancer Res. 2026 Sep 29. doi: 10.1158/0008-5472.CAN-26-0575.
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  4. ZHANG L, Zheng X, Fu H, Liu L, et al
    Inhibiting PPM1D Perturbs Mitochondrial Integrity to Stimulate cGAS-STING Signaling and Antitumor Immunity.
    Cancer Res. 2026;86:4551-4568.
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  5. SHI S, Yan J, Zhang Y, Zhang Y, et al
    Chemotherapy Reawakens Dormant Disseminated Pancreatic Cancer Cells in the Liver by Promoting Senescent Hepatocyte-Induced Neutrophil Extracellular Traps.
    Cancer Res. 2026 Sep 4. doi: 10.1158/0008-5472.CAN-26-0151.
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    August 2026
  6. JIANG F, Chen L, Yang YC, Wang XM, et al
    Retraction: CYP3A5 Functions as a Tumor Suppressor in Hepatocellular Carcinoma by Regulating mTORC2/Akt Signaling.
    Cancer Res. 2026;86:4187-4188.
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    July 2026
  7. LI J, Ren Z, Yao J, Zhao Y, et al
    Mechanosensors Collaborate to Regulate DNA Damage Repair in Hepatocellular Carcinoma.
    Cancer Res. 2026 Jul 29. doi: 10.1158/0008-5472.CAN-25-4356.
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  8. XU S, Huang JY, Wang K, Xiang YJ, et al
    ARID1A Stimulates Notch-TLL1 Signaling to Induce Cancer-Associated Fibroblast Activation and Intrahepatic Cholangiocarcinoma Development.
    Cancer Res. 2026 Jul 17. doi: 10.1158/0008-5472.CAN-25-5082.
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  9. SUN T, Sun Q, Zhang X, Wang C, et al
    SEPTIN7 Enhances Tumorgenesis and Therapeutic Resistance in Hepatocellular Carcinoma by Promoting FGFR4 Stabilization and Recycling.
    Cancer Res. 2026 Jul 6. doi: 10.1158/0008-5472.CAN-25-5924.
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  10. QIU W, Zeng Y, Fan Z, Su Y, et al
    An SLCO2B1 mRNA Isoform Acts as a Noncoding RNA to Drive Cancer Progression by Triggering Protein Biosynthesis.
    Cancer Res. 2026;86:3142-3159.
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    June 2026
  11. GU H, Li F, Chen Y, Zhang M, et al
    EGFR N-Glycosylation Catalyzed by NDST2 Promotes Lenvatinib Resistance in Hepatocellular Carcinoma.
    Cancer Res. 2026 Jun 22. doi: 10.1158/0008-5472.CAN-25-4582.
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  12. ZENG Y, Huang Z, Qiu J, Yuan G, et al
    HSPA6 Confers Lenvatinib Resistance in Hepatocellular Carcinoma by Promoting Phase Separation-Mediated TXNRD1 Stabilization to Suppress Ferroptosis.
    Cancer Res. 2026 Jun 18. doi: 10.1158/0008-5472.CAN-26-0314.
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    May 2026
  13. SRIRAMAREDDY S, Siddarajappa N, Park JS, Nguyen T, et al
    GDF15 Reprograms the Microenvironment to Drive Liver Metastasis of Uveal Melanoma.
    Cancer Res. 2026 May 28. doi: 10.1158/0008-5472.CAN-25-0536.
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    April 2026
  14. XU M, Gao X, Zhao J, Xu D, et al
    UFMylation Suppresses Hepatocellular Carcinoma Metastasis by Inhibiting beta-catenin-Driven Hybrid EMT and NK Cell Evasion.
    Cancer Res. 2026 Apr 17. doi: 10.1158/0008-5472.CAN-25-4755.
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  15. GREENE E, Horvat NK, Doxie DB, Parihar VC, et al
    High-Dimensional Protein Analysis Uncovers Distinct Immunologic and Stromal Features in Primary and Metastatic Pancreatic Ductal Adenocarcinoma.
    Cancer Res. 2026;86:1753-1768.
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    March 2026
  16. HAN L, Huo Y, Yang Y, Zhang L, et al
    The tRNA-Derived Fragment tRF-E Promotes Ferroptosis in Hepatocellular Carcinoma to Suppress Tumor Progression.
    Cancer Res. 2026 Mar 26. doi: 10.1158/0008-5472.CAN-25-2492.
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  17. SUN Y, Luo C, Yang H, Ye J, et al
    Lactylation Converts ABHD6 into a Mitochondrial Regulator that Drives Lenvatinib Resistance in Hepatocellular Carcinoma.
    Cancer Res. 2026 Mar 20. doi: 10.1158/0008-5472.CAN-25-4282.
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  18. BARROWS KM, Porat-Shliom N
    Hot Zones for Liver Cancer: Metabolic Zonation, Ferroptosis, and the Origins of HCC.
    Cancer Res. 2026;86:1347-1350.
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    February 2026
  19. JO W, Park C, Kim M, Kim CS, et al
    Endotrophin and CD44-Mediated Heterotypic Signaling Mediates Tumor-Stroma Crosstalk and Facilitates Malignant Progression in Hepatocellular Carcinoma.
    Cancer Res. 2026 Feb 11. doi: 10.1158/0008-5472.CAN-25-3657.
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    January 2026
  20. LIU Q, Liu Y, Zhou Y, Liang L, et al
    Intratumoral Lactobacillus johnsonii Enhances Sensitivity to PD-1 Blockade by Inducing CD8+ T Cell Expansion in Hepatocellular Carcinoma.
    Cancer Res. 2026 Jan 22. doi: 10.1158/0008-5472.CAN-25-0346.
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    October 2025
  21. LIU S, Zhang Z, Wang Z, Liu C, et al
    SPP1 Drives Colorectal Cancer Liver Metastasis and Immunotherapy Resistance by Stimulating CXCL12 Production in Cancer-Associated Fibroblasts.
    Cancer Res. 2025 Oct 6. doi: 10.1158/0008-5472.CAN-24-4916.
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    September 2025
  22. MODL B, Zwolanek D, Schwertner K, Krauss D, et al
    TYK2 Promotes Immunosurveillance of Colorectal Cancer Liver Metastasis.
    Cancer Res. 2025 Sep 24. doi: 10.1158/0008-5472.CAN-24-4224.
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  23. CUI G, Zhou Y, Liao W, Cossu E, et al
    Inhibition of GSK3 and TSC2 Mediates the Oncogenic Activity of AKT in Hepatocellular Carcinoma.
    Cancer Res. 2025 Sep 12. doi: 10.1158/0008-5472.CAN-25-1615.
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  24. FU C, Fu W, Huang Z, He X, et al
    Long-Chain Fatty Acid Redistribution Induced by SLC27A2 Deficiency Facilitates Hypoxic Adaptation and Immunosuppression in Hepatocellular Carcinoma.
    Cancer Res. 2025 Sep 3. doi: 10.1158/0008-5472.CAN-25-1693.
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  25. WU YD, Huang XX, Zhang HX, Pan Y, et al
    TRAF3IP2-AS1 Deficiency Induces Necroptosis to Promote Pancreatic Cancer Liver Metastasis.
    Cancer Res. 2025;85:3292-3312.
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    August 2025
  26. ZHENG Z, Yuan F, Li J, Zhu X, et al
    Gut Microbiota-Mediated Bile Acid Metabolism Regulates Colorectal Cancer Liver Metastasis by Altering Neutrophil Recruitment.
    Cancer Res. 2025 Aug 27. doi: 10.1158/0008-5472.CAN-24-4425.
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  27. RUAN YH, Ning WR, Huang AQ, Jiang D, et al
    Intracellular Interleukin-1alpha in Peritumoral Monocytes Induces IL8 Production and Inhibits Mitophagy to Promote Stemness and Metastasis of Hepatocellular Carcinoma.
    Cancer Res. 2025 Aug 26. doi: 10.1158/0008-5472.CAN-24-3355.
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  28. LIU Y, Liu FS, Liu J, Cairang D, et al
    The Acetyltransferase ARD1 Induces Glutathione Synthesis to Facilitate Ferroptosis Evasion in Hepatocellular Carcinoma.
    Cancer Res. 2025 Aug 21. doi: 10.1158/0008-5472.CAN-24-4015.
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  29. GONG X, Ogino N, Leite MF, Zhang D, et al
    Adaptation to Volumetric Compression Drives an Apoptosis-Resistant and Invasive Phenotype in Liver Cancer.
    Cancer Res. 2025;85:3156-3175.
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  30. CHEN K, Feng H, Zhang Y, Pei J, et al
    Tumor-derived CCL16 Normalizes Tumor Vasculature through Macrophage ICAM-1 Receptor and Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma.
    Cancer Res. 2025 Aug 12. doi: 10.1158/0008-5472.CAN-24-4323.
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  31. ZHANG X, Su T, Wu Y, Cai Y, et al
    Correction: N6-Methyladenosine Reader YTHDF1 Promotes Stemness and Therapeutic Resistance in Hepatocellular Carcinoma by Enhancing NOTCH1 Expression.
    Cancer Res. 2025;85:2953.
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    July 2025
  32. LI RZ, Pan GQ, Xiong C, Ding ZN, et al
    Hypoxia-Induced Creatine Uptake Reprograms Metabolism to Antagonize PARP1-Mediated Cell Death and Facilitate Tumor Progression in Hepatocellular Carcinoma.
    Cancer Res. 2025 Jul 31. doi: 10.1158/0008-5472.CAN-25-0301.
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  33. YANG H, Cui J, Su P, Cui X, et al
    Oxytocin Receptor Regulates the Hippo/YAP Axis to Drive Hepatocarcinogenesis.
    Cancer Res. 2025 Jul 31. doi: 10.1158/0008-5472.CAN-24-3405.
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  34. LU J, Chan TT, Wang Y, Wang J, et al
    FADD Activation in Hepatocellular Carcinoma Potentiates CD8+T Cell Responses and Sensitizes to Immune Checkpoint Inhibitors.
    Cancer Res. 2025 Jul 14. doi: 10.1158/0008-5472.CAN-24-3854.
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    May 2025
  35. PAPARGYRIOU A, Reichert M
    The Biology in the Pattern: Metastatic Organotropism and Clinical Outcome Depend on DNA Damage Response and Immune Interactions in Pancreatic Cancer.
    Cancer Res. 2025;85:1571-1573.
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    March 2025
  36. LEE TKW, Ma S
    PROX1: a key regulator of hepatocyte identity and tumorigenesis.
    Cancer Res. 2025 Mar 31. doi: 10.1158/0008-5472.CAN-25-1377.
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  37. CHANG Y, Wang N, Li S, Zhang J, et al
    SLC3A2-Mediated Lysine Uptake by Cancer Cells Restricts T cell Activity in Hepatocellular Carcinoma.
    Cancer Res. 2025 Mar 24. doi: 10.1158/0008-5472.CAN-24-3180.
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  38. WANG M, Zou F, Wang S, Yang Y, et al
    CRTC2 Forms Co-condensates with YTHDF2 that Enhance Translational Efficiency of m6A-Modified mRNAs to Drive Hepatocarcinogenesis and Lenvatinib Resistance.
    Cancer Res. 2025 Mar 4. doi: 10.1158/0008-5472.CAN-24-3196.
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    January 2025
  39. CHEN R, Ma C, Qian H, Xie X, et al
    Mutant KRAS and CK2 Cooperatively Stimulate SLC16A3 Activity to Drive Intrahepatic Cholangiocarcinoma Progression.
    Cancer Res. 2025 Jan 24. doi: 10.1158/0008-5472.CAN-24-2097.
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  40. XIE P, Guo L, Yu Q, Zhao Y, et al
    ACE2 Enhances Sensitivity to PD-L1 Blockade by Inhibiting Macrophage-Induced Immunosuppression and Angiogenesis.
    Cancer Res. 2025;85:299-313.
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  41. LUO YW, Fang Y, Zeng HX, Ji YC, et al
    HIF1alpha Counteracts TGFbeta1-Driven TSP1 Expression in Endothelial Cells to Stimulate Angiogenesis in the Hypoxic Tumor Microenvironment.
    Cancer Res. 2025;85:69-83.
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    December 2024
  42. XUE S, Chen X, Qiu G, Liao H, et al
    CLK1 Activates YAP to Promote Intrahepatic Cholangiocarcinogenesis.
    Cancer Res. 2024 Dec 18. doi: 10.1158/0008-5472.CAN-24-0147.
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  43. TURNHAM RE, Pitea A, Jang GM, Xu Z, et al
    HBV Remodels PP2A Complexes to Rewire Kinase Signaling in Hepatocellular Carcinoma.
    Cancer Res. 2024 Dec 9. doi: 10.1158/0008-5472.CAN-24-0456.
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  44. YANG Y, Luo J, Wang Z, Liu K, et al
    Energy Stress-induced CircEPB41(2) Promotes Lipogenesis in Hepatocellular Carcinoma.
    Cancer Res. 2024 Dec 5. doi: 10.1158/0008-5472.CAN-24-1630.
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    November 2024
  45. ZHANG Q, Zhang Y, Fu C, He X, et al
    CSTF2 Supports Hypoxia Tolerance in Hepatocellular Carcinoma by Enabling m6A Modification Evasion of PGK1 to Enhance Glycolysis.
    Cancer Res. 2024 Nov 8. doi: 10.1158/0008-5472.CAN-24-2283.
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    October 2024
  46. CUI Y, Chang Y, Ma X, Sun M, et al
    Ephrin A1 Stimulates CCL2 Secretion to Facilitate Pre-metastatic Niche Formation and Promote Gastric Cancer Liver Metastasis.
    Cancer Res. 2024 Oct 16. doi: 10.1158/0008-5472.CAN-24-1254.
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    September 2024
  47. CONNER SJ, Borges HB, Guarin JR, Gerton TJ, et al
    Obesity Induces Temporally Regulated Alterations in the Extracellular Matrix That Drive Breast Tumor Invasion and Metastasis.
    Cancer Res. 2024;84:2761-2775.
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  48. SHU Y, Jin X, Ji M, Zhang Z, et al
    Ku70 Binding to YAP Alters PARP1 Ubiquitination to Regulate Genome Stability and Tumorigenesis.
    Cancer Res. 2024;84:2836-2855.
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  49. HOU PP, Zheng CM, Wu SH, Liu XX, et al
    Extracellular Vesicle-Packaged ACSL4 Induces Hepatocyte Senescence to Promote Hepatocellular Carcinoma Progression.
    Cancer Res. 2024 Sep 3. doi: 10.1158/0008-5472.CAN-24-0832.
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    August 2024
  50. ZHANG S, Deshpande A, Verma BK, Wang H, et al
    Integration of Clinical Trial Spatial Multiomics Analysis and Virtual Clinical Trials Enables Immunotherapy Response Prediction and Biomarker Discovery.
    Cancer Res. 2024;84:2734-2748.
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    July 2024
  51. LIAO S, Deng J, Deng M, Chen C, et al
    AFDN deficiency promotes liver tropism of metastatic colorectal cancer.
    Cancer Res. 2024 Jul 24. doi: 10.1158/0008-5472.CAN-23-3140.
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    June 2024
  52. SHIRANI M, Levin S, Shebl B, Requena D, et al
    Increased Protein Kinase A Activity Induces Fibrolamellar Hepatocellular Carcinoma Features Independent of DNAJB1.
    Cancer Res. 2024 Jun 18. doi: 10.1158/0008-5472.CAN-23-4110.
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  53. LI L, Xie D, Yu S, Ma M, et al
    WNK1 Interaction with KEAP1 Promotes NRF2 Stabilization to Enhance the Oxidative Stress Response in Hepatocellular Carcinoma.
    Cancer Res. 2024 Jun 17. doi: 10.1158/0008-5472.CAN-23-1167.
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    May 2024
  54. RETTIG AR, Ganesh K
    Cancer Cells Hijack Physiologic Metabolic Signals to Seed Liver Metastasis.
    Cancer Res. 2024;84:1548-1549.
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  55. HE W, Wang M, Zhang X, Wang Y, et al
    Estrogen induces LCAT to maintain cholesterol homeostasis and suppress hepatocellular carcinoma development.
    Cancer Res. 2024 May 8. doi: 10.1158/0008-5472.CAN-23-3966.
    >> Share

  56. ZHANG R, Li S, Schippers K, Li Y, et al
    Analysis of Tumor-Associated AXIN1 Missense Mutations Identifies Variants That Activate beta-Catenin Signaling.
    Cancer Res. 2024;84:1443-1459.
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    April 2024
  57. YANG S, Zhang D, Sun Q, Nie H, et al
    Single-Cell and Spatial Transcriptome Profiling Identifies the Transcription Factor BHLHE40 as a Driver of EMT in Metastatic Colorectal Cancer.
    Cancer Res. 2024 Apr 24. doi: 10.1158/0008-5472.CAN-23-3264.
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    March 2024
  58. HUANG J, Tsang WY, Fang XN, Zhang Y, et al
    FASN Inhibition Decreases MHC-I Degradation and Synergizes with PD-L1 Checkpoint Blockade in Hepatocellular Carcinoma.
    Cancer Res. 2024;84:855-871.
    >> Share

  59. WENG J, Wang Z, Hu Z, Xu W, et al
    Repolarization of immunosuppressive macrophages by targeting SLAMF7-regulated CCL2 signaling sensitizes hepatocellular carcinoma to immunotherapy.
    Cancer Res. 2024 Mar 14. doi: 10.1158/0008-5472.CAN-23-3106.
    >> Share

  60. LIAO H, Chen X, Wang H, Lin Y, et al
    Whole-genome DNA methylation profiling of intrahepatic cholangiocarcinoma reveals prognostic subtypes with distinct biological drivers.
    Cancer Res. 2024 Mar 12. doi: 10.1158/0008-5472.CAN-23-3298.
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  61. WAN S, He QY, Yang Y, Liu F, et al
    SPARC stabilizes ApoE to induce cholesterol-dependent invasion and sorafenib resistance in hepatocellular carcinoma.
    Cancer Res. 2024 Mar 12. doi: 10.1158/0008-5472.CAN-23-2889.
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    February 2024
  62. WANG Y, Cheng C, Lu Y, Lian Z, et al
    beta-catenin Activation Reprograms Ammonia Metabolism to Promote Senescence Resistance in Hepatocellular Carcinoma.
    Cancer Res. 2024 Feb 28. doi: 10.1158/0008-5472.CAN-23-0673.
    >> Share

  63. SONG M, Zhang C, Cheng S, Ouyang D, et al
    DNA of neutrophil extracellular traps binds TMCO6 to impair CD8+ T-cell immunity in hepatocellular carcinoma.
    Cancer Res. 2024 Feb 21. doi: 10.1158/0008-5472.CAN-23-2986.
    >> Share

  64. LIU X, Wang X, Yang Q, Luo L, et al
    Th17 cells secrete TWEAK to trigger epithelial-mesenchymal transition and promote colorectal cancer liver metastasis.
    Cancer Res. 2024 Feb 9. doi: 10.1158/0008-5472.CAN-23-2123.
    >> Share

    January 2024
  65. ZHANG X, Su T, Wu Y, Cai Y, et al
    N6-methyladenosine reader YTHDF1 promotes stemness and therapeutic resistance in hepatocellular carcinoma by enhancing NOTCH1 expression.
    Cancer Res. 2024 Jan 19. doi: 10.1158/0008-5472.CAN-23-1916.
    >> Share

  66. MU M, Huang CX, Qu C, Li PL, et al
    Targeting ferroptosis-elicited inflammation suppresses hepatocellular carcinoma metastasis and enhances sorafenib efficacy.
    Cancer Res. 2024 Jan 17. doi: 10.1158/0008-5472.CAN-23-1796.
    >> Share

    December 2023
  67. DATTA J, Kutay H, Nasser MW, Nuovo GJ, et al
    Retraction: Methylation Mediated Silencing of MicroRNA-1 Gene and Its Role in Hepatocellular Carcinogenesis.
    Cancer Res. 2023;83:4181.
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  68. MAJUMDER S, Roy S, Kaffenberger T, Wang B, et al
    Retraction: Loss of Metallothionein Predisposes Mice to Diethylnitrosamine-Induced Hepatocarcinogenesis by Activating NF-kappaB Target Genes.
    Cancer Res. 2023;83:4179.
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    November 2023
  69. ZHUANG Q, Dai Z, Xu X, Bai S, et al
    RNA methyltransferase FTSJ3 regulates the type I interferon pathway to promote hepatocellular carcinoma immune evasion.
    Cancer Res. 2023 Nov 14. doi: 10.1158/0008-5472.CAN-23-2049.
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  70. CHEN Z, Zhang G, Ren X, Yao Z, et al
    Cross-talk between Myeloid and B Cells Shapes the Distinct Microenvironments of Primary and Secondary Liver Cancer.
    Cancer Res. 2023;83:3544-3561.
    >> Share

    September 2023
  71. SU T, Zhang N, Wang T, Zeng J, et al
    Super enhancer-regulated lncRNA LINC01089 induces alternative splicing of DIAPH3 to drive hepatocellular carcinoma metastasis.
    Cancer Res. 2023 Sep 26. doi: 10.1158/0008-5472.CAN-23-0544.
    >> Share

  72. HUNG MH, Wang XW
    Targeting WNT/beta-catenin via modulating EZH2 function - a new chapter in the treatment of beta-catenin mutant hepatocellular carcinoma?
    Cancer Res. 2023 Sep 25. doi: 10.1158/0008-5472.CAN-23-2921.
    >> Share

    August 2023
  73. ZHENG Y, Zhou R, Cai J, Yang N, et al
    Matrix stiffness triggers lipid metabolic crosstalk between tumor and stromal cells to mediate bevacizumab resistance in colorectal cancer liver metastases.
    Cancer Res. 2023 Aug 23:CAN-23-0025. doi: 10.1158/0008-5472.CAN-23-0025.
    >> Share


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