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Articles published in
Cancer Res
    June 2023
  1. MATSUMOTO S, Harada A, Seta M, Akita M, et al
    Wnt Signaling Stimulates Cooperation between GREB1 and HNF4alpha to Promote Proliferation in Hepatocellular Carcinoma.
    Cancer Res. 2023 Jun 22:OF1-OF16. doi: 10.1158/0008-5472.CAN-22-3518.
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  2. ZHANG Q, Wei T, Yan L, Zhu S, et al
    Hypoxia-responsive lncRNA AC115619 encodes a micropeptide that suppresses m6A modifications and hepatocellular carcinoma progression.
    Cancer Res. 2023 Jun 16:CAN-23-0337. doi: 10.1158/0008-5472.CAN-23-0337.
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  3. SCHEPERS EJ, Glaser K, Zwolshen HM, Hartman SJ, et al
    Structural and Functional Impact of Posttranslational Modification of Glypican-3 on Liver Carcinogenesis.
    Cancer Res. 2023;83:1933-1940.
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    May 2023
  4. BEI Y, He J, Dong X, Wang Y, et al
    Targeting CD44 variant 5 with an antibody-drug conjugate is an effective therapeutic strategy for intrahepatic cholangiocarcinoma.
    Cancer Res. 2023 May 19:CAN-23-0510. doi: 10.1158/0008-5472.CAN-23-0510.
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  5. ZHOU Q, Li L, Sha F, Lei Y, et al
    PTTG1 reprograms asparagine metabolism to promote hepatocellular carcinoma progression.
    Cancer Res. 2023 May 9:CAN-22-3561. doi: 10.1158/0008-5472.CAN-22-3561.
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  6. MUNSON PV, Adamik J, Hartmann FJ, Favaro PMB, et al
    Polyunsaturated Fatty Acid-Bound alpha-Fetoprotein Promotes Immune Suppression by Altering Human Dendritic Cell Metabolism.
    Cancer Res. 2023;83:1543-1557.
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    April 2023
  7. WOOD CS, Pennel KAF, Leslie H, Legrini A, et al
    Spatially Resolved Transcriptomics Deconvolutes Prognostic Histological Subgroups in Patients with Colorectal Cancer and Synchronous Liver Metastases.
    Cancer Res. 2023;83:1329-1344.
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  8. FANG JH, Chen JY, Zheng JL, Zeng HX, et al
    Fructose Metabolism in Tumor Endothelial Cells Promotes Angiogenesis by Activating AMPK Signaling and Mitochondrial Respiration.
    Cancer Res. 2023;83:1249-1263.
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    December 2022
  9. DHANASEKARAN R, Hansen AS, Park J, Lemaitre L, et al
    MYC Overexpression Drives Immune Evasion in Hepatocellular Carcinoma that is Reversible Through Restoration of Pro-Inflammatory Macrophages.
    Cancer Res. 2022 Dec 16:CAN-22-0232. doi: 10.1158/0008-5472.CAN-22-0232.
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  10. HAN J, Meng J, Chen S, Wang X, et al
    Correction: YY1 Complex Promotes Quaking Expression via Super-Enhancer Binding during EMT of Hepatocellular Carcinoma.
    Cancer Res. 2022;82:4694.
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  11. CHENG X, Tan X, Wang W, Zhang Z, et al
    Long-chain acylcarnitines induce senescence of invariant natural killer T cells in hepatocellular carcinoma.
    Cancer Res. 2022 Dec 13:CAN-22-2273. doi: 10.1158/0008-5472.CAN-22-2273.
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  12. TEIJEIRA A, Garasa S, Luri-Rey C, de Andrea C, et al
    Depletion of Conventional Type-1 Dendritic Cells in Established Tumors Suppresses Immunotherapy Efficacy.
    Cancer Res. 2022;82:4373-4385.
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    November 2022
  13. WUESTEFELD A, Iakovleva V, Yap SXL, Ong ABL, et al
    A pro-regenerative environment triggers premalignant to malignant transformation of senescent hepatocytes.
    Cancer Res. 2022 Nov 30:CAN-22-1477. doi: 10.1158/0008-5472.CAN-22-1477.
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  14. ZHU X, Song G, Zhang S, Chen J, et al
    Asialoglycoprotein Receptor 1 Functions as a Tumor Suppressor in Liver Cancer via Inhibition of STAT3.
    Cancer Res. 2022;82:3987-4000.
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    October 2022
  15. DUDA DG, Jain RK
    Revisiting Antiangiogenic Multikinase Inhibitors in the Era of Immune Checkpoint Blockade: The Case of Sorafenib.
    Cancer Res. 2022;82:3665-3667.
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    September 2022
  16. XIAO Y, Li Y, Shi D, Wang X, et al
    MEX3C-mediated decay of SOCS3 mRNA promotes JAK2/STAT3 signaling to facilitate metastasis in hepatocellular carcinoma.
    Cancer Res. 2022 Sep 16. pii: 709244. doi: 10.1158/0008-5472.CAN-22-1203.
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  17. MAN K, Pang L, Yeung OWH, Ng KTP, et al
    Postoperative plasmacytoid dendritic cells secrete IFN-alpha to promote recruitment of myeloid-derived suppressor cells and drive hepatocellular carcinoma recurrence.
    Cancer Res. 2022 Sep 14. pii: 709225. doi: 10.1158/0008-5472.CAN-22-1199.
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  18. HUANG M, Long J, Yao Z, Zhao Y, et al
    METTL1-mediated m7G tRNA modification promotes lenvatinib resistance in hepatocellular carcinoma.
    Cancer Res. 2022 Sep 14. pii: 709196. doi: 10.1158/0008-5472.CAN-22-0963.
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  19. HU B, Zou T, Qin W, Shen X, et al
    Inhibition of EGFR overcomes acquired lenvatinib resistance driven by STAT3-ABCB1 signaling in hepatocellular carcinoma.
    Cancer Res. 2022 Sep 6. pii: 708982. doi: 10.1158/0008-5472.CAN-21-4140.
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    August 2022
  20. BARTON MC, Lozano G
    p53 Activation Paradoxically Causes Liver Cancer.
    Cancer Res. 2022;82:2824-2825.
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    July 2022
  21. PRIVES C, Suzuki S, Venkatesh D, Kanda H, et al
    GLS2 is a tumor suppressor and a regulator of ferroptosis in hepatocellular carcinoma.
    Cancer Res. 2022 Jul 27. pii: 707287. doi: 10.1158/0008-5472.CAN-21-3914.
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  22. LI Y, Li B, Xu Y, Qian L, et al
    GOT2 Silencing Promotes Reprogramming of Glutamine Metabolism and Sensitizes Hepatocellular Carcinoma to Glutaminase Inhibitors.
    Cancer Res. 2022 Jul 27. pii: 707288. doi: 10.1158/0008-5472.CAN-22-0042.
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  23. WANG JC, Chen DP, Lu SX, Chen JB, et al
    PIM2 expression induced by proinflammatory macrophages suppresses immunotherapy efficacy in hepatocellular carcinoma.
    Cancer Res. 2022 Jul 11. pii: 706923. doi: 10.1158/0008-5472.CAN-21-3899.
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  24. XIE C, Wang FY, Sang Y, Chen B, et al
    Mitochondrial Micropeptide STMP1 Enhances Mitochondrial Fission to Promote Tumor Metastasis.
    Cancer Res. 2022;82:2431-2443.
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    June 2022
  25. MOK EH, Leung CO, Zhou L, Lei MML, et al
    Caspase-3-induced activation of SREBP2 drives drug resistance via promotion of cholesterol biosynthesis in hepatocellular carcinoma.
    Cancer Res. 2022 Jun 29. pii: 705310. doi: 10.1158/0008-5472.CAN-21-2934.
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  26. SHAN H, Liu T, Gan H, He S, et al
    RNA helicase DDX24 stabilizes LAMB1 to promote hepatocellular carcinoma progression.
    Cancer Res. 2022 Jun 28. pii: 705275. doi: 10.1158/0008-5472.CAN-21-3748.
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  27. MAKINO Y, Hikita H, Fukumoto K, Sung JH, et al
    Constitutive activation of the tumor suppressor p53 in hepatocytes paradoxically promotes non-cell autonomous liver carcinogenesis.
    Cancer Res. 2022 Jun 13. pii: 704882. doi: 10.1158/0008-5472.CAN-21-4390.
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    May 2022
  28. HEINZ MC, Peters NA, Oost KC, Lindeboom RGH, et al
    Liver Colonization by Colorectal Cancer Metastases Requires YAP-Controlled Plasticity at the Micrometastatic Stage.
    Cancer Res. 2022;82:1953-1968.
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  29. LIU Z, Ye Y, Liu Y, Liu Y, et al
    RNA Helicase DHX37 Facilitates Liver Cancer Progression by Cooperating with PLRG1 to Drive Superenhancer-Mediated Transcription of Cyclin D1.
    Cancer Res. 2022;82:1937-1952.
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    April 2022
  30. CHENG Y, Bai F, Ren X, Sun R, et al
    Phosphoinositide-Binding Protein TIPE1 Promotes Alternative Activation of Macrophages and Tumor Progression via PIP3/Akt/TGFbeta Axis.
    Cancer Res. 2022;82:1603-1616.
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  31. BAYARD Q, Cordier P, Peneau C, Imbeaud S, et al
    Structure, Dynamics, and Impact of Replication Stress-Induced Structural Variants in Hepatocellular Carcinoma.
    Cancer Res. 2022 Apr 8:OF1-OF12. doi: 10.1158/0008-5472.CAN-21-3665.
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    January 2022
  32. LI J, Hu ZQ, Yu S, Mao L, et al
    CircRPN2 inhibits aerobic glycolysis and metastasis in hepatocellular carcinoma.
    Cancer Res. 2022 Jan 19. pii: 0008-5472.CAN-21-1259.
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  33. ADACHI Y, Kamiyama H, Ichikawa K, Fukushima S, et al
    Inhibition of FGFR Reactivates IFNgamma Signaling in Tumor Cells to Enhance the Combined Antitumor Activity of Lenvatinib with Anti-PD-1 Antibodies.
    Cancer Res. 2022;82:292-306.
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    December 2021
  34. MA WK, Voss DM, Scharner J, Costa ASH, et al
    ASO-based PKM splice-switching therapy inhibits hepatocellular carcinoma growth.
    Cancer Res. 2021 Dec 17. pii: 0008-5472.CAN-20-0948.
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  35. CHEN Y, Ling Z, Cai X, Xu Y, et al
    Activation of YAP1 by N6-methyladenosine-modified CircCPSF6 Drives Malignancy in Hepatocellular Carcinoma.
    Cancer Res. 2021 Dec 16. pii: 0008-5472.CAN-21-1628.
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  36. XU F, Tong M, Tong CSW, Chan BKC, et al
    A Combinatorial CRISPR-Cas9 Screen Identifies Ifenprodil as an Adjunct to Sorafenib for Liver Cancer Treatment.
    Cancer Res. 2021;81:6219-6232.
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  37. BELLIDO MOLIAS F, Sim A, Leong KW, An O, et al
    Antisense RNAs Influence Promoter Usage of Their Counterpart Sense Genes in Cancer.
    Cancer Res. 2021;81:5849-5861.
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    November 2021
  38. PEASE DR, Fernandez-Zapico ME
    mTOR-Dependent ARID1A Degradation: A New Twist in the Genetic-Epigenetic Interplay Driving Hepatocellular Carcinoma.
    Cancer Res. 2021;81:5608-5610.
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  39. REN X, Rong Z, Liu X, Gao J, et al
    The protein kinase activity of NME7 activates Wnt/beta-Catenin signaling to promote one-carbon metabolism in hepatocellular carcinoma.
    Cancer Res. 2021 Nov 11. pii: 0008-5472.CAN-21-1020.
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  40. SENDI H, Yazdimamaghani M, Hu M, Sultanpuram N, et al
    Nanoparticle delivery of miR-122 inhibits colorectal cancer liver metastasis.
    Cancer Res. 2021 Nov 9. pii: 0008-5472.CAN-21-2269.
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    October 2021
  41. BARCENA-VARELA M, Lujambio A
    A Novel Long Noncoding RNA Finetunes the DNA Damage Response in Hepatocellular Carcinoma.
    Cancer Res. 2021;81:4899-4900.
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    September 2021
  42. LOH JJ, Li TW, Zhou L, Wong TL, et al
    FSTL1 secreted by activated fibroblasts promotes hepatocellular carcinoma metastasis and stemness.
    Cancer Res. 2021 Sep 22. pii: 0008-5472.CAN-20-4226.
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  43. KAN X, Zhou G, Zhang F, Ji H, et al
    Interventional Optical Imaging Permits Instant Visualization of Pathological Zones of Ablated Tumor Periphery and Residual Tumor Detection.
    Cancer Res. 2021;81:4594-4602.
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    August 2021
  44. ZHANG S, Zhou YF, Cao J, Burley SK, et al
    mTORC1 Promotes ARID1A Degradation and Oncogenic Chromatin Remodeling in Hepatocellular Carcinoma.
    Cancer Res. 2021 Aug 24. pii: 0008-5472.CAN-21-0206.
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    July 2021
  45. UNFRIED JP, Marin-Baquero M, Rivera-Calzada A, Razquin N, et al
    Long noncoding RNA NIHCOLE promotes ligation efficiency of DNA double-strand breaks in hepatocellular carcinoma.
    Cancer Res. 2021 Jul 28. pii: 0008-5472.CAN-21-0463.
    >> Share

  46. QIU X, Yang S, Wang S, Wu J, et al
    M6A Demethylase ALKBH5 Regulates PD-L1 Expression and Tumor Immunoenvironment in Intrahepatic Cholangiocarcinoma.
    Cancer Res. 2021 Jul 23. pii: 0008-5472.CAN-21-0468.
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  47. TANG M, Yang M, Wu G, Mo S, et al
    Epigenetic Induction of Mitochondrial Fission Is Required for Maintenance of Liver Cancer-Initiating Cells.
    Cancer Res. 2021;81:3835-3848.
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  48. PARK M, Kim JW, Kim KM, Kang S, et al
    Circulating Small Extracellular Vesicles Activate TYRO3 to Drive Cancer Metastasis and Chemoresistance.
    Cancer Res. 2021;81:3539-3553.
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    June 2021
  49. SHRIKI A, Lanton T, Sonnenblick A, Levkovitch-Siany O, et al
    Multiple Roles of IL-6 in Hepatic Injury, Steatosis, and Senescence Aggregate to Suppress Tumorigenesis.
    Cancer Res. 2021 Jun 11. pii: 0008-5472.CAN-21-0321.
    >> Share

  50. GONZALEZ-ROMERO F, Mestre D, Aurrekoetxea I, O'Rourke CJ, et al
    E2F1 and E2F2-Mediated Repression of CPT2 Establishes a Lipid-Rich Tumor-Promoting Environment.
    Cancer Res. 2021;81:2874-2887.
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  51. LULLI M, Del Coco L, Mello T, Sukowati C, et al
    DNA Damage Response Protein CHK2 Regulates Metabolism in Liver Cancer.
    Cancer Res. 2021;81:2861-2873.
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    May 2021
  52. ZHAO Z, Gad H, Benitez-Buelga C, Sanjiv K, et al
    NEIL3 prevents senescence in hepatocellular carcinoma by repairing oxidative lesions at telomeres during mitosis.
    Cancer Res. 2021 May 27. pii: 0008-5472.CAN-20-1028.
    >> Share

  53. MA APY, Yeung CLS, Tey SK, Mao X, et al
    Suppression of ACADM-mediated fatty acid oxidation promotes hepatocellular carcinoma via aberrant Cav1/SREBP-1 signaling.
    Cancer Res. 2021 May 11. pii: 0008-5472.CAN-20-3944.
    >> Share

    April 2021
  54. LEUNG HW, Leung CO, Lau EY, Chung KPS, et al
    EPHB2 activates beta-catenin to enhance cancer stem cell properties and drive sorafenib resistance in hepatocellular carcinoma.
    Cancer Res. 2021 Apr 26. pii: 0008-5472.CAN-21-0184.
    >> Share

  55. DU L, Li Y, Kang M, Feng M, et al
    USP48 is upregulated by Mettl14 to attenuate hepatocellular carcinoma via regulating SIRT6 stabilization.
    Cancer Res. 2021 Apr 26. pii: 0008-5472.CAN-20-4163.
    >> Share

  56. RICCIOTTI E, Wangensteen KJ, FitzGerald GA
    Aspirin in hepatocellular carcinoma.
    Cancer Res. 2021 Apr 23. pii: 0008-5472.CAN-21-0758.
    >> Share

  57. FUHRMAN BJ, Moore SC, Byrne C, Makhoul I, et al
    Association of the Age at Menarche with Site-Specific Cancer Risks in Pooled Data from Nine Cohorts.
    Cancer Res. 2021;81:2246-2255.
    >> Share

  58. BROADFIELD LA, Duarte JAG, Schmieder R, Broekaert D, et al
    Fat Induces Glucose Metabolism in Nontransformed Liver Cells and Promotes Liver Tumorigenesis.
    Cancer Res. 2021;81:1988-2001.
    >> Share

    February 2021
  59. ZHOU J, Li Q, Cao Y
    Spatiotemporal Heterogeneity Across Metastases and Organ-Specific Response Informs Drug Efficacy and Patient Survival in Colorectal Cancer.
    Cancer Res. 2021 Feb 15. pii: 0008-5472.CAN-20-3665.
    >> Share

  60. DAVENPORT ML, Echols JB, Silva AD, Anderson JC, et al
    miR-31 displays subtype specificity in lung cancer.
    Cancer Res. 2021 Feb 8. pii: 0008-5472.CAN-20-2769.
    >> Share

    January 2021
  61. YAMADA K, Oikawa T, Kizawa R, Motohashi S, et al
    Unconventional Secretion of PKCdelta Exerts Tumorigenic Function via Stimulation of ERK1/2 Signaling in Liver Cancer.
    Cancer Res. 2021;81:414-425.
    >> Share

  62. HONG SH, Son KH, Ha SY, Wee TI, et al
    Nucleoporin 210 Serves a Key Scaffold for SMARCB1 in Liver Cancer.
    Cancer Res. 2021;81:356-370.
    >> Share

  63. GENG Y, Fan J, Chen L, Zhang C, et al
    A Notch-Dependent Inflammatory Feedback Circuit between Macrophages and Cancer Cells Regulates Pancreatic Cancer Metastasis.
    Cancer Res. 2021;81:64-76.
    >> Share

  64. BATTISTELLI C, Garbo S, Riccioni V, Montaldo C, et al
    Design and Functional Validation of a Mutant Variant of the LncRNA HOTAIR to Counteract Snail Function in Epithelial-to-Mesenchymal Transition.
    Cancer Res. 2021;81:103-113.
    >> Share

    October 2020
  65. WILLS CA, Liu X, Chen L, Zhao Y, et al
    Chemotherapy-Induced Upregulation of Small Extracellular Vesicle-Associated PTX3 Accelerates Breast Cancer Metastasis.
    Cancer Res. 2020 Oct 28. pii: 0008-5472.CAN-20-1976.
    >> Share


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