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Articles published in
Am J Pathol
    June 2024
  1. LAURENT-BELLUE A, Sadraoui A, Claude L, Calderaro J, et al
    Deep learning classification and quantification of pejorative and non-pejorative architectures in resected hepatocellular carcinoma from digital histopathological images.
    Am J Pathol. 2024 Jun 13:S0002-9440(24)00206.
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  2. ZHANG Y, Liu Y, Huo W, He L, et al
    The Role of miRNA and Long Noncoding RNA in Cholestatic Liver Diseases.
    Am J Pathol. 2024;194:879-893.
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    May 2024
  3. MARTUCCI NJ, Stoops J, Bowen W, Orr A, et al
    A novel role for the phosphatidylinositol-4,5-bisphosphate 3-kinase delta isoform in hepatocellular proliferation.
    Am J Pathol. 2024 May 3:S0002-9440(24)00168-8. doi: 10.1016/j.ajpath.2024.
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    April 2024
  4. HU J, Xu H, Ma X, Bai M, et al
    Modulating PCGF4 Stability Is an Efficient Metastasis-Regulatory Strategy Used by Distinct Subtypes of Cancer-Associated Fibroblasts in Intrahepatic Cholangiocarcinoma.
    Am J Pathol. 2024 Apr 24:S0002-9440(24)00160.
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    March 2024
  5. NGO HV, Thanh Le TT, Vu HN, Hoang H, et al
    Poorly Differentiated Hepatocellular Carcinoma Cells Avoid Apoptosis by Interacting with T Cells via CD40-CD40L Linkage.
    Am J Pathol. 2024 Mar 26:S0002-9440(24)00117.
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  6. YU YP, Liu S, Geller D, Luo JH, et al
    Serum fusion transcripts to assess the risk of hepatocellular carcinoma and the impact of cancer treatment through machine learning.
    Am J Pathol. 2024 Mar 25:S0002-9440(24)00111.
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    February 2024
  7. NEWBERRY EP, Molitor EA, Liu A, Chong K, et al
    Impaired hepatic VLDL secretion promotes tumorigenesis and is accelerated with Fabp1 deletion.
    Am J Pathol. 2024 Feb 26:S0002-9440(24)00074.
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  8. LIAN V, Hinrichs H, Young M, Faerber A, et al
    Maternal Obesogenic Diet Attenuates Microbiome-Dependent Offspring Weaning Reaction with Worsening of Steatotic Liver Disease.
    Am J Pathol. 2024;194:209-224.
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  9. ABUDUYIMITI T, Goto H, Kimura K, Oshima Y, et al
    Diabetes accelerates steatohepatitis in mice: liver pathology and single-cell gene expression signatures.
    Am J Pathol. 2024 Feb 1:S0002-9440(24)00037-3. doi: 10.1016/j.ajpath.2024.
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    December 2023
  10. TAN PK, Ostertag T, Rosenthal SB, Chilin-Fuentes D, et al
    Role of Hepatic Stellate and Liver Sinusoidal Endothelial Cells in a Human Primary Cell Three-Dimensional Model of Nonalcoholic Steatohepatitis.
    Am J Pathol. 2023 Dec 28:S0002-9440(23)00484.
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  11. WEN T, Xie J, Ma L, Hao Z, et al
    Vitamin D receptor activation reduces hepatic inflammation via enhancing macrophage autophagy in cholestatic mice.
    Am J Pathol. 2023 Dec 15:S0002-9440(23)00462.
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  12. JIANG C, Saiki Y, Hirota S, Iwata K, et al
    Ablation of Dual-Specificity Phosphatase 6 Protects against Nonalcoholic Fatty Liver Disease via Cytochrome P450 4A and Mitogen-Activated Protein Kinase.
    Am J Pathol. 2023;193:1988-2000.
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  13. VENKATESAN N, Doskey LC, Malhi H
    The Role of Endoplasmic Reticulum in Lipotoxicity during Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Pathogenesis.
    Am J Pathol. 2023;193:1887-1899.
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    November 2023
  14. WARNER JB, Hardesty JE, Song YL, Floyd AT, et al
    Hepatic Transcriptome and Its Regulation Following Soluble Epoxide Hydrolase Inhibition in Alcohol-Associated Liver Disease.
    Am J Pathol. 2023 Nov 2:S0002-9440(23)00410-8. doi: 10.1016/j.ajpath.2023.
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    October 2023
  15. FENG R, Tong C, Lin T, Liu H, et al
    Insulin determines TGF-beta effects on HNF4alpha transcription in hepatocytes.
    Am J Pathol. 2023 Oct 9:S0002-9440(23)00365-6. doi: 10.1016/j.ajpath.2023.
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  16. MAIERS JL, Chakraborty S
    The Cellular, Molecular, and Pathologic Consequences of Stress on the Liver.
    Am J Pathol. 2023;193:1353-1354.
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  17. ISMAIL A, Kennedy L, Francis H
    Sex-Dependent Differences in Cholestasis: Why Estrogen Signaling May Be a Key Pathophysiological Driver.
    Am J Pathol. 2023;193:1355-1362.
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  18. BANERJEE P, Gaddam N, Chandler V, Chakraborty S, et al
    Oxidative Stress-Induced Liver Damage and Remodeling of the Liver Vasculature.
    Am J Pathol. 2023;193:1400-1414.
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  19. JACKSON KG, Way GW, Zeng J, Lipp MK, et al
    The Dynamic Role of Endoplasmic Reticulum Stress in Chronic Liver Disease.
    Am J Pathol. 2023;193:1389-1399.
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  20. ALI N, Ferrao K, Mehta KJ
    Liver Iron Loading in Alcohol-Associated Liver Disease.
    Am J Pathol. 2023;193:1427-1439.
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    September 2023
  21. FITZGERALD H, Bonin JL, Khan S, Eid M, et al
    Resolvin D2-GPR18 Enhances Bone Marrow Function and Limits Steatosis and Hepatic Collagen Accumulation in Aging.
    Am J Pathol. 2023 Sep 15:S0002-9440(23)00322.
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  22. TANAKA M, Jeong J, Thomas C, Zhang X, et al
    The sympathetic nervous system promotes hepatic lymphangiogenesis, which is protective against liver fibrosis.
    Am J Pathol. 2023 Sep 4:S0002-9440(23)00308-5. doi: 10.1016/j.ajpath.2023.
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  23. CHAN KK, Au KY, Suen LH, Leung B, et al
    Am J Pathol. 2023 Sep 4:S0002-9440(23)00310-3. doi: 10.1016/j.ajpath.2023.
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    August 2023
  24. MAIRINOJA L, Heikela H, Blom S, Kumar D, et al
    Deep Learning-Based Image Analysis of Liver Steatosis in Mouse Models.
    Am J Pathol. 2023;193:1072-1080.
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    July 2023
  25. PANT K, Venugopal SK, Lorenzo Pisarello MJ, Gradilone SA, et al
    The Role of Gut Microbiome-Derived Short Chain Fatty Acid Butyrate in Hepatobiliary Diseases.
    Am J Pathol. 2023 Jul 6:S0002-9440(23)00238-9. doi: 10.1016/j.ajpath.2023.
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  26. HANQUIER Z, Misra J, Baxter R, Maiers JL, et al
    Stress and Liver Fibrogenesis: Understanding the role and regulation of stress response pathways in Hepatic Stellate Cells.
    Am J Pathol. 2023 Jul 6:S0002-9440(23)00237-7. doi: 10.1016/j.ajpath.2023.
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    June 2023
  27. CHEN PC, Hsu CP, Wang SY, Wu TY, et al
    miR-194 Up-Regulates Cholesterol 7 Alpha-Hydroxylase Expression via beta-Catenin Signaling and Aggravates Cholestatic Liver Diseases.
    Am J Pathol. 2023;193:755-768.
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    May 2023
  28. CHEN Y, Pan Q, Liao W, Ai W, et al
    Transcription factor Foxo1 mediates TGF-beta1-induced apoptosis in hepatocytes.
    Am J Pathol. 2023 May 30:S0002-9440(23)00199.
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    March 2023
  29. QIAN H, Ding WX
    SQSTM1/p62 and Hepatic Mallory Denk Body Formation in Alcohol-Associated Liver Disease.
    Am J Pathol. 2023 Mar 9:S0002-9440(23)00084-6. doi: 10.1016/j.ajpath.2023.
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  30. HRNCIR HR, Hantelys F, Gracz AD
    Panic at the Bile Duct: How Intrahepatic Cholangiocytes Respond to Stress and Injury.
    Am J Pathol. 2023 Mar 2:S0002-9440(23)00063-9. doi: 10.1016/j.ajpath.2023.
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    January 2023
  31. YUAN X, Bhat OM, Zou Y, Zhang Y, et al
    Contribution of Hepatic Steatosis-intensified Extracellular Vesicle Release to Aggravated Inflammatory Endothelial Injury in Liver-Specific Asah1 Gene Knockout Mice.
    Am J Pathol. 2023 Jan 10:S0002-9440(23)00001.
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    November 2022
  32. SAPONARA E, Penno C, Orsini V, Wang ZY, et al
    Loss of Hepatic Lgr4 and Lgr5 Promotes Nonalcoholic Fatty Liver Disease.
    Am J Pathol. 2022 Nov 18:S0002-9440(22)00358.
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  33. HURLEY EH, Tao J, Liu S, Krutsenko Y, et al
    Inhibition of HSF1 Signaling Decreases Hepatoblastoma Growth Via Induction of Apoptosis.
    Am J Pathol. 2022 Nov 3. pii: S0002-9440(22)00355.
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    October 2022
  34. JABER FL, Sharma Y, Gupta S
    Hepatocyte Transplantation Rebalances Cytokines for Hepatic Regeneration in Rats with Ataxia Telangiectasia Mutated Pathway-Related Acute Liver Failure.
    Am J Pathol. 2022 Oct 27. pii: S0002-9440(22)00318.
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  35. LUNA-MARCO C, Ubink A, Kopsida M, Heindryckx F, et al
    Endoplasmic Reticulum Stress and Metabolism in Hepatocellular Carcinoma.
    Am J Pathol. 2022 Oct 26. pii: S0002-9440(22)00322.
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  36. ARGEMI J, Kedia K, Gritsenko MA, Clemente-Sanchez A, et al
    Integrated Transcriptomic and Proteomic Analysis Identifies Plasma Biomarkers of Hepatocellular Failure in Alcohol-Associated Hepatitis.
    Am J Pathol. 2022 Oct 13. pii: S0002-9440(22)00310.
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    September 2022
  37. JIAO J, Jiang Y, Qian Y, Liu G, et al
    Expression of STING is increased in monocyte-derived macrophages and contributes to liver inflammation in hepatic ischemia-reperfusion injury.
    Am J Pathol. 2022 Sep 26. pii: S0002-9440(22)00285.
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    August 2022
  38. DONG MP, Thanh Thuy LT, Hoang DV, Hai H, et al
    Soluble Immune Checkpoint Protein CD27 Is a Novel Prognostic Biomarker of Hepatocellular Carcinoma Development in Hepatitis C Virus-Sustained Virological Response Patients.
    Am J Pathol. 2022 Aug 11. pii: S0002-9440(22)00207.
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    June 2022
  39. ROY N, Alencastro F, Roseman BA, Wilson SR, et al
    Dysregulation of Lipid and Glucose Homeostasis in Hepatocyte-Specific SLC25A34 Knockout Mice.
    Am J Pathol. 2022 Jun 16. pii: S0002-9440(22)00172.
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  40. PHAM L, Kyritsi K, Zhou T, Ceci L, et al
    The Functional Roles of Immune Cells in Primary Liver Cancer.
    Am J Pathol. 2022;192:826-836.
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    April 2022
  41. HARDESTY J, Day L, Warner J, Warner D, et al
    Hepatic protein and phosphoprotein signatures of alcohol-associated cirrhosis and hepatitis.
    Am J Pathol. 2022 Apr 28. pii: S0002-9440(22)00121.
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  42. KORAL K, Bhushan B, Orr A, Stoops J, et al
    Lymphocyte specific protein 1 suppresses xenobiotic-induced CAR and subsequent YAP activated hepatocyte proliferation.
    Am J Pathol. 2022 Apr 4. pii: S0002-9440(22)00110.
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    January 2022
  43. GOEL C, Monga SP, Nejak-Bowen K
    Role and Regulation of Wnt/beta-Catenin in Hepatic Perivenous Zonation and Physiological Homeostasis.
    Am J Pathol. 2022;192:4-17.
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    December 2021
  44. RANI R, Sharma A, Wang J, Kumar S, et al
    Endotoxin-stimulated hepatic stellate cells augment acetaminophen-induced hepatocyte injury.
    Am J Pathol. 2021 Dec 23. pii: S0002-9440(21)00529.
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  45. DIAO S, Tian Y, Hu W, Hou J, et al
    Weakly Supervised Framework for Cancer Regions Detection of Hepatocellular Carcinoma in Whole-Slide Pathologic Images Based on Multiscale Attention Convolutional Neural Network.
    Am J Pathol. 2021 Dec 9. pii: S0002-9440(21)00524.
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  46. PETRESCU AD, Grant S, Williams E, An SY, et al
    Leptin Enhances Hepatic Fibrosis and Inflammation in a Mouse Model of Cholestasis.
    Am J Pathol. 2021 Dec 8. pii: S0002-9440(21)00523.
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  47. ROY S, Banerjee P, Ekser B, Bayless K, et al
    Targeting Lymphangiogenesis and Lymph Node Metastasis in Liver Cancer.
    Am J Pathol. 2021;191:2052-2063.
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    November 2021
  48. BATHULA CS, Chen J, Kumar R, Blackshear PJ, et al
    ZFP36L1 regulates Fgf21 mRNA turnover and modulates alcoholic hepatic steatosis and inflammation in mice.
    Am J Pathol. 2021 Nov 11. pii: S0002-9440(21)00478.
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    October 2021
  49. CHAO X, Wang S, Hlobik M, Ballabio A, et al
    Loss of Hepatic Transcription Factor EB Attenuates Alcohol-Associated Liver Carcinogenesis.
    Am J Pathol. 2021 Oct 27. pii: S0002-9440(21)00442.
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  50. ICHIMURA-SHIMIZU M, Tsuchiyama Y, Morimoto Y, Matsumoto M, et al
    A novel mouse model of non-alcoholic steatohepatitis suggests that liver fibrosis initiates around lipid-laden macrophages.
    Am J Pathol. 2021 Oct 25. pii: S0002-9440(21)00440.
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  51. GOTTLIEB A, Dev S, DeVine L, Gabrielson KL, et al
    Am J Pathol. 2021 Oct 7. pii: S0002-9440(21)00435.
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  52. This Month in AJP.
    Am J Pathol. 2021;191:1669.
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    September 2021
  53. BARAJAS JM, Lin CH, Sun HL, Alencastro F, et al
    METTL3 Regulates Liver Homeostasis, Hepatocyte Ploidy, and Circadian Rhythm-Controlled Gene Expression in Mice.
    Am J Pathol. 2021 Sep 29. pii: S0002-9440(21)00430.
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  54. This Month in AJP.
    Am J Pathol. 2021;191:1489.
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  55. LEE SW, Baek SM, Kang KK, Lee AR, et al
    Vitamin C Deficiency Inhibits Nonalcoholic Fatty Liver Disease Progression through Impaired de Novo Lipogenesis.
    Am J Pathol. 2021;191:1550-1563.
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  56. MENG L, Goto M, Tanaka H, Kamikokura Y, et al
    Decreased Portal Circulation Augments Fibrosis and Ductular Reaction in Nonalcoholic Fatty Liver Disease in Mice.
    Am J Pathol. 2021;191:1580-1591.
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    August 2021
  57. KANG MJ, Lee S, Jung U, Mandal C, et al
    Inhibition of hepatic stellate cell activation suppresses tumorigenicity of hepatocellular carcinoma in mice.
    Am J Pathol. 2021 Aug 21. pii: S0002-9440(21)00352.
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    July 2021
  58. MATTHEWS DR, Li H, Zhou J, Li Q, et al
    Methionine- and Choline-deficient Diet-induced Non-alcoholic Steatohepatitis Is Associated with Increased Intestinal Inflammation.
    Am J Pathol. 2021 Jul 6. pii: S0002-9440(21)00302.
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  59. BLOOMER SA, Brown KE
    Hepcidin and Iron Metabolism in Experimental Liver Injury.
    Am J Pathol. 2021;191:1165-1179.
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    June 2021
  60. BAGLIERI J, Zhang C, Liang S, Liu X, et al
    Non-degradable collagen increases liver fibrosis but not hepatocellular carcinoma in mice.
    Am J Pathol. 2021 Jun 10. pii: S0002-9440(21)00254.
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  61. WU MS, Kuo YP, Lo YC, Tsai DJ, et al
    Type I Interferon Signaling Accelerates Liver Regeneration by Metabolic Modulation in Noninfectious Conditions.
    Am J Pathol. 2021;191:1036-1048.
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    May 2021
  62. CHEN Z, Jiang L, Liang L, Koral K, et al
    The Role of Fibroblast Growth Factor 19 in Hepatocellular Carcinoma.
    Am J Pathol. 2021 May 14. pii: S0002-9440(21)00198.
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  63. ZHANG Y, Liang B, Song X, Wang H, et al
    Loss of Apc Cooperates with Activated Oncogenes to Induce Liver Tumor Formation in Mice.
    Am J Pathol. 2021;191:930-946.
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    April 2021
  64. CHEN CY, Li Y, Zeng N, He L, et al
    Inhibition of estrogen related receptor alpha blocks liver steatosis and steatohepatitis and attenuates triglyceride biosynthesis.
    Am J Pathol. 2021 Apr 21. pii: S0002-9440(21)00162.
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