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Articles published in
Am J Pathol
    July 2025
  1. LIU J, Li J, Li Y, Wei M, et al
    Transcription Factor YY2 Inhibits Tumor Cell Glutamine Catabolism by Regulating GLS1 RNA Splicing Isoform GAC.
    Am J Pathol. 2025;195:1340-1357.
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    June 2025
  2. ZHONG H, Liu C, Huang Z, Tan P, et al
    Crosstalk between Hepatic Stellate Cells and Hepatic Macrophages in Metabolic Dysfunction-Associated Steatohepatitis.
    Am J Pathol. 2025;195:1040-1056.
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    May 2025
  3. XUE Y, Tian T, Ottallah M, Mannan M, et al
    Alcohol-Associated Hepatocarcinogenesis: Wnt/beta-Catenin in Action.
    Am J Pathol. 2025 May 9:S0002-9440(25)00156-7. doi: 10.1016/j.ajpath.2025.
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  4. KEEGAN A, Malamal G, Lee Y, Korolowicz K, et al
    Multimodal Diagnostic Imaging of Metabolic Dysfunction-Associated Steatotic Liver Disease: Noninvasive Analyses by Photoacoustic Ultrasound and Magnetic Resonance Imaging.
    Am J Pathol. 2025;195:875-890.
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    April 2025
  5. RODEMANN MM, Dreschmann V, Dorner E, Sommer A, et al
    Identification of a growth-promoting gene cluster in the region 2q24 as a driver of tumorigenesis in childhood hepatoblastoma.
    Am J Pathol. 2025 Apr 30:S0002-9440(25)00147.
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  6. XU L, Zhao Y, Yang Y, Qi E, et al
    Constitutive hepatic mTORC1 activation aggravates alcohol-induced liver injury via endoplasmic reticulum stress-mediated ferroptosis.
    Am J Pathol. 2025 Apr 7:S0002-9440(25)00106-3. doi: 10.1016/j.ajpath.2025.
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    March 2025
  7. WANG Z, Liang G, Peng J, Gu Y, et al
    Sirtuin 7 Promotes Alcohol-Associated Liver Injury via Modulating Myeloid Cell Chemokine (C-C Motif) Ligand 2 Secretion through the NF-kappaB Signaling Pathway.
    Am J Pathol. 2025;195:575-588.
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  8. CASILLAS-RAMIREZ A, Maroto-Serrat C, Sanus F, Mico-Carnero M, et al
    Regulation of Adiponectin and Resistin in Liver Transplantation Protects Grafts from Extended-Criteria Donors.
    Am J Pathol. 2025;195:494-527.
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    February 2025
  9. KHA M, Magnusson Y, Johansson I, Altiparmak G, et al
    Injured Proximal Tubular Epithelial Cells Lose Hepatocyte Nuclear Factor 4alpha Expression Crucial for Brush Border Formation and Transport.
    Am J Pathol. 2025 Feb 13:S0002-9440(25)00047.
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    January 2025
  10. CHEN K, Wang H, Ma B, Knapp J, et al
    Gas1-Mediated Suppression of Hepatoblastoma Tumorigenesis.
    Am J Pathol. 2025 Jan 29:S0002-9440(25)00037.
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  11. ISHIHARA N, Koma YI, Omori M, Komatsu S, et al
    CCL2/CCR2/Erk Signal Induced through Cancer Cell-Macrophage Interaction Contributes to Hepatocellular Carcinoma Progression.
    Am J Pathol. 2025 Jan 3:S0002-9440(24)00480-2. doi: 10.1016/j.ajpath.2024.
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    December 2024
  12. HUANG X, Zheng S, Li S, Huang Y, et al
    Machine learning-based pathomics model predicts ANGPT2 expression and prognosis in hepatocellular carcinoma.
    Am J Pathol. 2024 Dec 31:S0002-9440(24)00478.
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  13. ZUO R, Wang M, Wang YT, ShenTu Y, et al
    Ablation of Hepatic Asah1 Gene Disrupts Hepatic Lipid Homeostasis and Promotes Fibrotic Nonalcoholic Steatohepatitis in Mice.
    Am J Pathol. 2024 Dec 20:S0002-9440(24)00444.
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    November 2024
  14. TUFFS C, Dupovac M, Richter K, Holten S, et al
    Genetic Loss of HIF-Prolyl-Hydroxylase (PHD) 1, but not pharmacological Inhibition, mitigates hepatic fibrosis.
    Am J Pathol. 2024 Nov 18:S0002-9440(24)00411.
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  15. ZHANG H, Lei S, Zhuo H, Xu Y, et al
    TRIM24 Up-Regulates ORM2 to Alleviate Abnormal Lipid Metabolism, Inflammation, and Oxidative Stress in Mice with Obstructive Sleep Apnea Syndrome and Metabolic Dysfunction-Associated Steatotic Liver Disease.
    Am J Pathol. 2024;194:2091-2105.
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  16. LI Z, Sun T, He Z, Li Z, et al
    Intestinal Dysbacteriosis Contributes to Persistent Cognitive Impairment after Resolution of Acute Liver Failure.
    Am J Pathol. 2024;194:2076-2090.
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    October 2024
  17. HUANG CC, Wang CH, Yeh HY, Tsai HC, et al
    Chronic Peroxisome Proliferator-Activated Receptor alpha/gamma and Cannabinoid Receptor 2 Agonist Treatments Attenuated Visceral Adipose Tissue (VAT)-Derived Extracellular Vesicle-Related VAT and Intestinal Abnormalities in Nonalcoholic Steatohepatitis
    Am J Pathol. 2024 Oct 26:S0002-9440(24)00398.
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    September 2024
  18. GUEST RV, Goeppert B, Nault JC, Sia D, et al
    Morphomolecular pathology and Genomic Insights into the Cells of Origin of Cholangiocarcinoma and combined Hepatocellular-Cholangiocarcinoma.
    Am J Pathol. 2024 Sep 26:S0002-9440(24)00357.
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  19. CHEON I, Kim M, Kim KH, Ko S, et al
    Hepatic Nuclear Receptors in Cholestasis-to-Cholangiocarcinoma Pathology.
    Am J Pathol. 2024 Sep 24:S0002-9440(24)00358.
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  20. LI J, Ding X, Yan W, Liu K, et al
    Tumor-derived Immunoglobulin-like transcript 4 promotes postoperative relapse via inducing vasculogenic mimicry through MAPK/ERK signaling in hepatocellular carcinoma.
    Am J Pathol. 2024 Sep 2:S0002-9440(24)00329-8. doi: 10.1016/j.ajpath.2024.
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    August 2024
  21. JIANG L, Xu QY, Zhou YC, Xu J, et al
    Spatial transcriptomics reveals the transcriptomic signatures in a mouse model of pediatric metabolic dysfunction-associated steatohepatitis.
    Am J Pathol. 2024 Aug 31:S0002-9440(24)00327.
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  22. LEYA M, Jeong H, Yang D, Bao THTN, et al
    Hepatocyte-specific casein kinase 1 epsilon ablation ameliorates metabolic dysfunction-associated steatohepatitis by upregulating TRAF3 in mice.
    Am J Pathol. 2024 Aug 21:S0002-9440(24)00299.
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  23. AFF? S, Sererols-Vinas L, Garcia-Vicien G, Cadamuro M, et al
    Cancer-Associated Fibroblasts in Intrahepatic Cholangiocarcinoma: Insights into Origins, Heterogeneity, Lymphangiogenesis, and Peritoneal Metastasis.
    Am J Pathol. 2024 Aug 6:S0002-9440(24)00279-7. doi: 10.1016/j.ajpath.2024.
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  24. PANT K, Gradilone SA
    NAMPT Overexpression Drives Cell Growth in Polycystic Liver Disease through Mitochondrial Metabolism Regulation.
    Am J Pathol. 2024;194:1528-1537.
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    July 2024
  25. YANG L, Pham K, Xi Y, Jiang S, et al
    Acyl-CoA Synthetase Medium Chain Family Member 5 Mediated Fatty Acid Metabolism Dysregulation Promotes the Progression of Hepatocellular Carcinoma.
    Am J Pathol. 2024 Jul 26:S0002-9440(24)00244.
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    June 2024
  26. LAURENT-BELLUE A, Sadraoui A, Claude L, Calderaro J, et al
    Deep learning classification and quantification of pejorative and non-pejorative architectures in resected hepatocellular carcinoma from digital histopathological images.
    Am J Pathol. 2024 Jun 13:S0002-9440(24)00206.
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  27. ZHANG Y, Liu Y, Huo W, He L, et al
    The Role of miRNA and Long Noncoding RNA in Cholestatic Liver Diseases.
    Am J Pathol. 2024;194:879-893.
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    May 2024
  28. MARTUCCI NJ, Stoops J, Bowen W, Orr A, et al
    A novel role for the phosphatidylinositol-4,5-bisphosphate 3-kinase delta isoform in hepatocellular proliferation.
    Am J Pathol. 2024 May 3:S0002-9440(24)00168-8. doi: 10.1016/j.ajpath.2024.
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    April 2024
  29. HU J, Xu H, Ma X, Bai M, et al
    Modulating PCGF4 Stability Is an Efficient Metastasis-Regulatory Strategy Used by Distinct Subtypes of Cancer-Associated Fibroblasts in Intrahepatic Cholangiocarcinoma.
    Am J Pathol. 2024 Apr 24:S0002-9440(24)00160.
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    March 2024
  30. NGO HV, Thanh Le TT, Vu HN, Hoang H, et al
    Poorly Differentiated Hepatocellular Carcinoma Cells Avoid Apoptosis by Interacting with T Cells via CD40-CD40L Linkage.
    Am J Pathol. 2024 Mar 26:S0002-9440(24)00117.
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  31. YU YP, Liu S, Geller D, Luo JH, et al
    Serum fusion transcripts to assess the risk of hepatocellular carcinoma and the impact of cancer treatment through machine learning.
    Am J Pathol. 2024 Mar 25:S0002-9440(24)00111.
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    February 2024
  32. NEWBERRY EP, Molitor EA, Liu A, Chong K, et al
    Impaired hepatic VLDL secretion promotes tumorigenesis and is accelerated with Fabp1 deletion.
    Am J Pathol. 2024 Feb 26:S0002-9440(24)00074.
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  33. LIAN V, Hinrichs H, Young M, Faerber A, et al
    Maternal Obesogenic Diet Attenuates Microbiome-Dependent Offspring Weaning Reaction with Worsening of Steatotic Liver Disease.
    Am J Pathol. 2024;194:209-224.
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  34. ABUDUYIMITI T, Goto H, Kimura K, Oshima Y, et al
    Diabetes accelerates steatohepatitis in mice: liver pathology and single-cell gene expression signatures.
    Am J Pathol. 2024 Feb 1:S0002-9440(24)00037-3. doi: 10.1016/j.ajpath.2024.
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    December 2023
  35. TAN PK, Ostertag T, Rosenthal SB, Chilin-Fuentes D, et al
    Role of Hepatic Stellate and Liver Sinusoidal Endothelial Cells in a Human Primary Cell Three-Dimensional Model of Nonalcoholic Steatohepatitis.
    Am J Pathol. 2023 Dec 28:S0002-9440(23)00484.
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  36. WEN T, Xie J, Ma L, Hao Z, et al
    Vitamin D receptor activation reduces hepatic inflammation via enhancing macrophage autophagy in cholestatic mice.
    Am J Pathol. 2023 Dec 15:S0002-9440(23)00462.
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  37. JIANG C, Saiki Y, Hirota S, Iwata K, et al
    Ablation of Dual-Specificity Phosphatase 6 Protects against Nonalcoholic Fatty Liver Disease via Cytochrome P450 4A and Mitogen-Activated Protein Kinase.
    Am J Pathol. 2023;193:1988-2000.
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  38. VENKATESAN N, Doskey LC, Malhi H
    The Role of Endoplasmic Reticulum in Lipotoxicity during Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Pathogenesis.
    Am J Pathol. 2023;193:1887-1899.
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    November 2023
  39. WARNER JB, Hardesty JE, Song YL, Floyd AT, et al
    Hepatic Transcriptome and Its Regulation Following Soluble Epoxide Hydrolase Inhibition in Alcohol-Associated Liver Disease.
    Am J Pathol. 2023 Nov 2:S0002-9440(23)00410-8. doi: 10.1016/j.ajpath.2023.
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    October 2023
  40. FENG R, Tong C, Lin T, Liu H, et al
    Insulin determines TGF-beta effects on HNF4alpha transcription in hepatocytes.
    Am J Pathol. 2023 Oct 9:S0002-9440(23)00365-6. doi: 10.1016/j.ajpath.2023.
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  41. MAIERS JL, Chakraborty S
    The Cellular, Molecular, and Pathologic Consequences of Stress on the Liver.
    Am J Pathol. 2023;193:1353-1354.
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  42. ISMAIL A, Kennedy L, Francis H
    Sex-Dependent Differences in Cholestasis: Why Estrogen Signaling May Be a Key Pathophysiological Driver.
    Am J Pathol. 2023;193:1355-1362.
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  43. BANERJEE P, Gaddam N, Chandler V, Chakraborty S, et al
    Oxidative Stress-Induced Liver Damage and Remodeling of the Liver Vasculature.
    Am J Pathol. 2023;193:1400-1414.
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  44. JACKSON KG, Way GW, Zeng J, Lipp MK, et al
    The Dynamic Role of Endoplasmic Reticulum Stress in Chronic Liver Disease.
    Am J Pathol. 2023;193:1389-1399.
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  45. ALI N, Ferrao K, Mehta KJ
    Liver Iron Loading in Alcohol-Associated Liver Disease.
    Am J Pathol. 2023;193:1427-1439.
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    September 2023
  46. FITZGERALD H, Bonin JL, Khan S, Eid M, et al
    Resolvin D2-GPR18 Enhances Bone Marrow Function and Limits Steatosis and Hepatic Collagen Accumulation in Aging.
    Am J Pathol. 2023 Sep 15:S0002-9440(23)00322.
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  47. TANAKA M, Jeong J, Thomas C, Zhang X, et al
    The sympathetic nervous system promotes hepatic lymphangiogenesis, which is protective against liver fibrosis.
    Am J Pathol. 2023 Sep 4:S0002-9440(23)00308-5. doi: 10.1016/j.ajpath.2023.
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  48. CHAN KK, Au KY, Suen LH, Leung B, et al
    SORTILIN-DRIVEN CANCER SECRETOME ENHANCES TUMORIGENIC PROPERTIES OF HEPATOCELLULAR CARCINOMA VIA DE NOVO LIPOGENESIS.
    Am J Pathol. 2023 Sep 4:S0002-9440(23)00310-3. doi: 10.1016/j.ajpath.2023.
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