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Articles published in
Proc Natl Acad Sci U S A
    October 2025
  1. TAN M, Sun S, Liu Y, Perreault AA, et al
    Targeting the 3D genome by anthracyclines for chemotherapeutic effects.
    Proc Natl Acad Sci U S A. 2025;122:e2500704122.
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  2. HATTORI T, Wang M, Corrado AD, Gross S, et al
    Engineering antibody-drug conjugates targeting an adhesion GPCR, CD97.
    Proc Natl Acad Sci U S A. 2025;122:e2516627122.
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    September 2025
  3. HAZIME KS, Sheppard S, Niembro-Vivanco O, Hosty C, et al
    Nanoscale restructuring of the immune synapse with an engager enhances NK cell function.
    Proc Natl Acad Sci U S A. 2025;122:e2507336122.
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  4. CHANG A, Pelletier AN, McGuire DJ, Tsagiopoulou M, et al
    PD-1 expression identifies proliferating malignant CLL B cells and is a potential biomarker of response to BTK inhibitor therapy.
    Proc Natl Acad Sci U S A. 2025;122:e2426935122.
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    July 2025
  5. FIERRO C, Giovannini S, Moriconi V, Fiorilli C, et al
    The WWP1-JARID1B axis sustains acute myeloid leukemia chemoresistance.
    Proc Natl Acad Sci U S A. 2025;122:e2421159122.
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  6. ZHANG W, Shichijo T, Chen X, Watanabe M, et al
    JunB-HBZ nuclear translocation by TGF-beta is a key driver in HTLV-1-mediated leukemogenesis.
    Proc Natl Acad Sci U S A. 2025;122:e2420756122.
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    June 2025
  7. MOBACH S, Bergkamp ND, Ma Z, Haselager MV, et al
    Disruption of constitutive CXCR4 oligomers impairs oncogenic properties in lymphoid neoplasms.
    Proc Natl Acad Sci U S A. 2025;122:e2424186122.
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    May 2025
  8. HOSSEINI A, Qiu X, Xiong Y, Chiang KHN, et al
    Discovery of an LSD1 PROTAC degrader.
    Proc Natl Acad Sci U S A. 2025;122:e2425812122.
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  9. SAKAMOTO T, Leca J, Zhang X, Meydan C, et al
    Mutant IDH1 cooperates with NPM1c or FLT3(ITD) to drive distinct myeloid diseases and molecular outcomes.
    Proc Natl Acad Sci U S A. 2025;122:e2415779122.
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    April 2025
  10. BERTULFO K, Perez-Duran P, Miller H, Ma C, et al
    Therapeutic targeting of the NOTCH1 and neddylation pathways in T cell acute lymphoblastic leukemia.
    Proc Natl Acad Sci U S A. 2025;122:e2426742122.
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  11. Correction to Supporting Information for Wang et al., Metabolomic insights into pathogenesis and therapeutic potential in adult acute lymphoblastic leukemia.
    Proc Natl Acad Sci U S A. 2025;122:e2504173122.
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    March 2025
  12. XU S, Hong J, Dongye M, Lin J, et al
    The synergistic effect of c-Myb hyperactivation and Pu.1 deficiency induces Pelger-Huet anomaly and promotes sAML.
    Proc Natl Acad Sci U S A. 2025;122:e2416121122.
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    February 2025
  13. LIU B, Yasunaga JI, Liang Y, Zhou R, et al
    Identification of AK4 and RHOC as potential oncogenes addicted by adult T cell leukemia.
    Proc Natl Acad Sci U S A. 2025;122:e2416412122.
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  14. WANG JY, Gui TT, Jiao B, Liu X, et al
    Metabolomic insights into pathogenesis and therapeutic potential in adult acute lymphoblastic leukemia.
    Proc Natl Acad Sci U S A. 2025;122:e2423169122.
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  15. JIN GB, Rong SQ, Yin DR, Deng ZH, et al
    Neomorphic leukemia-derived mutations in the TET2 enzyme induce genome instability via a substrate shift from 5-methylcytosine to thymine.
    Proc Natl Acad Sci U S A. 2025;122:e2418318122.
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    January 2025
  16. DONG Z, Sepulveda H, Arteaga-Vazquez LJ, Blouin C, et al
    A mutant ASXL1-BAP1-EHMT complex contributes to heterochromatin dysfunction in clonal hematopoiesis and chronic monomyelocytic leukemia.
    Proc Natl Acad Sci U S A. 2025;122:e2413302121.
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    December 2024
  17. NGUYEN HN, Jeong Y, Kim Y, Kamiya M, et al
    Leukemia inhibitory factor (LIF) receptor amplifies pathogenic activation of fibroblasts in lung fibrosis.
    Proc Natl Acad Sci U S A. 2024;121:e2401899121.
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    October 2024

  18. Correction for Garzon et al., Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin.
    Proc Natl Acad Sci U S A. 2024;121:e2419360121.
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  19. FU A, Luo Z, Ziv T, Bi X, et al
    Nuclear p62 condensates stabilize the promyelocytic leukemia nuclear bodies by sequestering their ubiquitin ligase RNF4.
    Proc Natl Acad Sci U S A. 2024;121:e2414377121.
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    September 2024

  20. Correction for Garzon et al., Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin.
    Proc Natl Acad Sci U S A. 2024;121:e2415544121.
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    August 2024
  21. ZHANG Y, Lou J, Liu Y, Jin P, et al
    Phase separation of PML/RARalpha and BRD4 coassembled microspeckles governs transcriptional dysregulation in acute promyelocytic leukemia.
    Proc Natl Acad Sci U S A. 2024;121:e2406519121.
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  22. LUO Y, Su B, Hung V, Luo Y, et al
    IL-1 receptor antagonism reveals a yin-yang relationship between NFkappaB and interferon signaling in chronic lymphocytic leukemia.
    Proc Natl Acad Sci U S A. 2024;121:e2405644121.
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    July 2024
  23. ZHONG X, Moresco JJ, SoRelle JA, Song R, et al
    Disruption of the ZFP574-THAP12 complex suppresses B cell malignancies in mice.
    Proc Natl Acad Sci U S A. 2024;121:e2409232121.
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    June 2024
  24. SMOLKO AE, Sullivan DW, Olsen SN, Kang H, et al
    A MOZ-TIF2 leukemia mouse model displays KAT6-dependent H3K23 propionylation and overexpression of a set of active developmental genes.
    Proc Natl Acad Sci U S A. 2024;121:e2405905121.
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  25. WINDISCH R, Soliman S, Hoffmann A, Chen-Wichmann L, et al
    Engineering an inducible leukemia-associated fusion protein enables large-scale ex vivo production of functional human phagocytes.
    Proc Natl Acad Sci U S A. 2024;121:e2312499121.
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    May 2024
  26. WOLF KMP, Maffeis V, Schoenenberger CA, Zund T, et al
    Tweaking the NRF2 signaling cascade in human myelogenous leukemia cells by artificial nano-organelles.
    Proc Natl Acad Sci U S A. 2024;121:e2219470121.
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    April 2024
  27. KATERNDAHL CDS, Rogers ORS, Day RB, Xu Z, et al
    PML::RARA and GATA2 proteins interact via DNA templates to induce aberrant self-renewal in mouse and human hematopoietic cells.
    Proc Natl Acad Sci U S A. 2024;121:e2317690121.
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  28. KRISTENSON L, Badami C, Ljungberg A, Islamagic E, et al
    Deletion of the TMEM30A gene enables leukemic cell evasion of NK cell cytotoxicity.
    Proc Natl Acad Sci U S A. 2024;121:e2316447121.
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    March 2024
  29. SHICHIJO T, Yasunaga JI, Sato K, Nosaka K, et al
    Vulnerability to APOBEC3G linked to the pathogenicity of deltaretroviruses.
    Proc Natl Acad Sci U S A. 2024;121:e2309925121.
    >> Share

  30. LI JF, Cheng WY, Lin XJ, Wen LJ, et al
    Aging and comprehensive molecular profiling in acute myeloid leukemia.
    Proc Natl Acad Sci U S A. 2024;121:e2319366121.
    >> Share

  31. ROSELLE C, Horikawa I, Chen L, Kelly AR, et al
    Enhancing chimeric antigen receptor T cell therapy by modulating the p53 signaling network with Delta133p53alpha.
    Proc Natl Acad Sci U S A. 2024;121:e2317735121.
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  32. KATSUMURA KR, Liu P, Kim JA, Mehta C, et al
    Pathogenic GATA2 genetic variants utilize an obligate enhancer mechanism to distort a multilineage differentiation program.
    Proc Natl Acad Sci U S A. 2024;121:e2317147121.
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    February 2024
  33. MOTTAGHINIA S, Stenzel S, Tsangaras K, Nikolaidis N, et al
    A recent gibbon ape leukemia virus germline integration in a rodent from New Guinea.
    Proc Natl Acad Sci U S A. 2024;121:e2220392121.
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    October 2023
  34. FERLITA A, Nigita G, Tsyba L, Palamarchuk A, et al
    Expression signature of human endogenous retroviruses in chronic lymphocytic leukemia.
    Proc Natl Acad Sci U S A. 2023;120:e2307593120.
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  35. NG A, Lovat F, Shih AJ, Ma Y, et al
    Complete miRNA-15/16 loss in mice promotes hematopoietic progenitor expansion and a myeloid-biased hyperproliferative state.
    Proc Natl Acad Sci U S A. 2023;120:e2308658120.
    >> Share


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