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Articles published in
J Biol Chem
    October 2026
  1. SHENG C, Xu Z, Hu C, Wu S, et al
    Biomimetic Sodium Transporters Induce Intracellular Sodium Overload to Activate p53-Mediated Apoptosis and Cell Cycle Arrest in Acute Myeloid Leukemia.
    J Biol Chem. 2026 Oct 22:113679. doi: 10.1016/j.jbc.2026.113679.
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  2. HARWARDT J, Pudewell S, Keil K, Lipinski B, et al
    LIF and let die: Generation, mechanistical and structural characterization of bispecific antibodies triggering leukemia inhibitory factor (LIF) receptor activation independent of the cytokine LIF.
    J Biol Chem. 2026 Oct 9:113634. doi: 10.1016/j.jbc.2026.113634.
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    September 2026
  3. STEWART E, Collins A, Kovacic B, Knupke M, et al
    Pathway incompatibility between NF-kappaB and RAS signaling constrains oncogenicity in B-cell leukemia.
    J Biol Chem. 2026 Sep 8:113537. doi: 10.1016/j.jbc.2026.113537.
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    June 2026
  4. ZHANG Y, Li Y, Li N, Zou C, et al
    ERK promotes miR34a/ISOC1 signaling to enhance all trans retinoic acid-induced myeloid differentiation in acute promyelocytic leukemia.
    J Biol Chem. 2026 Jun 20:113284. doi: 10.1016/j.jbc.2026.113284.
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    May 2026
  5. MADHULIKA S, Panda TS, Samal P, Kumar SS, et al
    Dysregulated HELLS expression alters cellular processes and serves as a potential prognostic marker in acute myeloid leukemia.
    J Biol Chem. 2026 May 28:113210. doi: 10.1016/j.jbc.2026.113210.
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    April 2026
  6. SHIRUDE MB, Devarajan A, Sahu SA, Mukherjee A, et al
    HIRA-SETDB1-H3K9me3 axis regulates chromatin architecture in leukemia cells.
    J Biol Chem. 2026 Apr 27:113081. doi: 10.1016/j.jbc.2026.113081.
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  7. ICHIKAWA T, Nakahata S, Shimoda K, Murakami T, et al
    The tumor suppressor NDRG2 recruits protein phosphatase 2A to suppress STAT5 phosphorylation in adult T-cell leukemia/lymphoma.
    J Biol Chem. 2026 Apr 27:113080. doi: 10.1016/j.jbc.2026.113080.
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  8. YAO G, Yang Y, Chen C, Zheng B, et al
    Ubiquitin E3 Ligase MYCBP2 Targets KIF14 and Contributes to Acute Myeloid Leukemia Progression.
    J Biol Chem. 2026 Apr 24:112204. doi: 10.1016/j.jbc.2026.112204.
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    March 2026
  9. FAUST JR, Hamill D, Kolb EA, Stevens AM, et al
    Mesothelin Promotes Acute Myeloid Leukemia Progression through LYN-dependent Signaling.
    J Biol Chem. 2026 Mar 20:111390. doi: 10.1016/j.jbc.2026.111390.
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    February 2026
  10. MICHAIL C, Berthelet J, Mechaly AE, Bui LC, et al
    The SETD2 L1609P mutation found in leukemia disrupts methyltransferase activity and reduces histone H3K36 trimethylation.
    J Biol Chem. 2026 Feb 5:111259. doi: 10.1016/j.jbc.2026.111259.
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  11. GONZALEZ-AREIZAGA G, Smithgall TE
    Chaperone-assisted expression and purification of the AML-associated Src-family kinase Fgr in Escherichia coli.
    J Biol Chem. 2026;302:111099.
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  12. CAO Q, Wang Y, Duan Y
    Dynamic and extensive A-to-I RNA recoding in immunoglobulin shapes myeloid neoplasm transcriptome.
    J Biol Chem. 2026;302:111066.
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    January 2026
  13. YADAV A, Richartz N, Bhagwat S, Burman MM, et al
    Starvation of leukemic cells enhances DNA damage-induced apoptosis in vitro via ROS/p38 MAPK and prevents leukemia progression in fasting xenograft mice.
    J Biol Chem. 2026 Jan 12:111143. doi: 10.1016/j.jbc.2026.111143.
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    December 2025
  14. WANG Y, Sen-Majumdar A, Li JM, Sarkar S, et al
    Identification and characterization of vasoactive intestinal peptide receptor antagonists with high-affinity and potent anti-leukemia activity.
    J Biol Chem. 2025 Dec 30:111127. doi: 10.1016/j.jbc.2025.111127.
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  15. YANG WS, Ghanem NZ, Scahill SD, Caliva MJ, et al
    Phosphorylation at S1288 of Leukemia Associated RhoGEF (LARG/ARHGEF12) induces plasma membrane localization and promotes binding and activation of RhoA.
    J Biol Chem. 2025 Dec 1:110996. doi: 10.1016/j.jbc.2025.110996.
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    September 2025
  16. PARK JH, Chung KC
    Ubiquitin-specific protease 7 promotes the growth and oncogenic potential of acute myeloid leukemia cells through the deubiquitination and upregulation of LRRK2.
    J Biol Chem. 2025 Sep 2:110675. doi: 10.1016/j.jbc.2025.110675.
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    August 2025
  17. WANG H, Suh F, Fischietti M, Wray B, et al
    The ubiquitin ligase Triad1 influences myeloid leukemogenesis by regulating the integrated stress response.
    J Biol Chem. 2025;301:110484.
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  18. ALES E, Sackstein R
    Restricted human CD45 isoglycoforms serve as functional E-selectin ligands and delineate hematopoietic maturity.
    J Biol Chem. 2025;301:110431.
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    July 2025
  19. ZHANG L, Zhong J, Yang L, Ye Q, et al
    The transcription factor HOXA9 induces expression of the chromatin modifier SMYD3 to drive leukemogenesis.
    J Biol Chem. 2025;301:110320.
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    May 2025
  20. SANG X, Guan Y, Jiang M, Chen X, et al
    Molecular Insights into Chemotherapy Resistance Mediated by MLL-AF9 Fusion Gene in Pediatric B-Cell Acute Lymphoblastic Leukemia.
    J Biol Chem. 2025 May 30:110321. doi: 10.1016/j.jbc.2025.110321.
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    March 2025
  21. ENKHBAYAR B, Lu SC, Tsai HY, Liang SY, et al
    Insights into the transcriptional regulation of CD22 in B cell chronic lymphocytic leukemia.
    J Biol Chem. 2025 Mar 5:108386. doi: 10.1016/j.jbc.2025.108386.
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  22. RAGHUWANSHI S, Magdy A, Hay N, Gartel A, et al
    A novel FOXM1-BCL2A1 axis determines unfavorable response to venetoclax in AML.
    J Biol Chem. 2025;301:108240.
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    January 2025
  23. HARDWICK J, Rodriguez-Hernaez J, Gambi G, Venters BJ, et al
    The common murine retroviral integration site activating Hhex marks a distal regulatory enhancer co-opted in human Early T-cell precursor leukemia.
    J Biol Chem. 2025 Jan 27:108233. doi: 10.1016/j.jbc.2025.108233.
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  24. SELZER AM, Gerlach G, Gonzalez-Areizaga G, Wales TE, et al
    An SH3-binding allosteric modulator stabilizes the global conformation of the AML-associated Src-family kinase, Hck.
    J Biol Chem. 2025;301:108088.
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    December 2024
  25. WU T, Sun Y, Wang D, Isaji T, et al
    The acetylglucosaminyltransferase GnT-? regulates erythroid differentiation through ERK/MAPK signaling.
    J Biol Chem. 2024;300:108010.
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    November 2024
  26. LIU P, Jiang J, Chen Y, Gao F, et al
    Identification of Cables1 as a critical host factor that promotes ALV-J replication via genome-wide CRISPR/Cas9 gene knockout screening.
    J Biol Chem. 2024;300:107804.
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    September 2024
  27. KOBROSSY L, Xu W, Zhang C, Feng W, et al
    Unraveling MLL1-fusion Leukemia: Epigenetic Revelations from an iPS Cell Point Mutation.
    J Biol Chem. 2024 Sep 27:107825. doi: 10.1016/j.jbc.2024.107825.
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    August 2024
  28. DUAN Y, Liu S, Wang J, Yang K, et al
    Overexpression of RBM4 promotes acute myeloid leukemia cell differentiation by regulating alternative splicing of TFEB.
    J Biol Chem. 2024 Aug 28:107729. doi: 10.1016/j.jbc.2024.107729.
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    July 2024
  29. RAMANI M, Singh RK, Shrivastva S, Ribeyron L, et al
    A pre-B acute lymphoblastic leukemia cell line model reveals the mechanism of thalidomide therapy related B-cell leukemogenesis.
    J Biol Chem. 2024 Jul 17:107578. doi: 10.1016/j.jbc.2024.107578.
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    March 2024
  30. KANEFSKY J, Basse M, Sokei J, di Martino O, et al
    DISRUPTION OF POLYUNSATURATED FATTY ACID BIOSYNTHESIS DRIVES STING-DEPENDENT ACUTE MYELOID LEUKEMIA CELL MATURATION AND DEATH.
    J Biol Chem. 2024 Mar 22:107214. doi: 10.1016/j.jbc.2024.107214.
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    November 2023
  31. RICHARTZ N, Pietka W, Yadav A, Bostad M, et al
    N-acetyl cysteine turns EPAC activators into potent killers of acute lymphoblastic leukemia cells.
    J Biol Chem. 2023 Nov 30:105509. doi: 10.1016/j.jbc.2023.105509.
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    October 2023
  32. NAMITZ KEW, Showalter SA, Cosgrove MS
    Phase separation promotes a highly active oligomeric scaffold of the MLL1 core complex for regulation of histone H3K4 methylation.
    J Biol Chem. 2023;299:105204.
    >> Share


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