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Articles published in
Cancer Res
    October 2026
  1. ZHANG L, Fu YH, Hua WK, Chen YC, et al
    The HDAC8-U2AF1 Axis Dysregulates DNA Damage-Responsive RNA Splicing and Creates Targetable Vulnerabilities in Acute Myeloid Leukemia.
    Cancer Res. 2026 Oct 8. doi: 10.1158/0008-5472.CAN-25-5027.
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    September 2026
  2. XIANG X, Luo B, Zhao L, Sui J, et al
    Targeting ClpP Rewires the Metabolic-Immune Axis in Acute Myeloid Leukemia.
    Cancer Res. 2026 Sep 28. doi: 10.1158/0008-5472.CAN-26-0477.
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    August 2026
  3. KIM BR, Kim H, Choi H, Kwag D, et al
    A Selective CK1alpha Degrader Targets Acute Myeloid Leukemia and Spares Normal Hematopoietic Cells.
    Cancer Res. 2026 Aug 3. doi: 10.1158/0008-5472.CAN-25-3629.
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    July 2026
  4. XU W, Ma X, Sun X, Song G, et al
    ETV6 Rearrangement Suppresses CDKN1B Transcription by Disrupting an Intragenic Super-Enhancer in Acute Lymphoblastic Leukemia.
    Cancer Res. 2026 Jul 29. doi: 10.1158/0008-5472.CAN-25-3743.
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  5. PASTRANA CC, Nonavinkere Srivatsan S, Alberti MO, Hossan T, et al
    Nonsense-Mediated RNA Decay Is a Targetable Vulnerability in Splicing Factor Mutant Myeloid Neoplasms by Enhancing R-Loop Accumulation and DNA Damage.
    Cancer Res. 2026;86:3537-3553.
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    June 2026
  6. FRANKHOUSER DE, Zhao D, Fu YH, Dey A, et al
    Longitudinal Single-Cell RNA-Sequencing Reveals Evolution of Micro- and Macro-states in Chronic Myeloid Leukemia.
    Cancer Res. 2026 Jun 22. doi: 10.1158/0008-5472.CAN-25-4371.
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  7. HAUPT S, di Agostino S, Mizrahi I, Alsheich-Bartok O, et al
    Editor's Note: Promyelocytic Leukemia Protein is Required for Gain of Function by Mutant p53.
    Cancer Res. 2026;86:3093.
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  8. ALLSUP DJ, Kamiguti AS, Lin K, Sherrington PD, et al
    Editor's Note: B-Cell Receptor Translocation to Lipid Rafts and Associated Signaling Differ Between Prognostically Important Subgroups of Chronic Lymphocytic Leukemia.
    Cancer Res. 2026;86:2823.
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    April 2026
  9. LAU BK, Haarer EL, Ahn JH, Wang GG, et al
    A Unified Model: Chromatin-Bound Multicomponent Condensates.
    Cancer Res. 2026;86:1543-1544.
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    March 2026
  10. HILGART E, Zhou W, Martinez-Montes E, Tryggvadottir R, et al
    DNA Methylation Stochasticity is Linked to Transcriptional Variability and Convergent Epigenetic Disruption Across Genetic Subtypes of Acute Myeloid Leukemia.
    Cancer Res. 2026 Mar 16. doi: 10.1158/0008-5472.CAN-25-5822.
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    November 2025
  11. ERIKSSON J, Zheng S, Popa M, Bao J, et al
    Single-Cell Lineage Tracing Uncovers Resistance Signatures and Sensitizing Strategies to FLT3 Inhibitors in Acute Myeloid Leukemia.
    Cancer Res. 2025 Nov 21. doi: 10.1158/0008-5472.CAN-24-3753.
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    October 2025
  12. IANEVSKI A, Nader K, Nguyen J, Sorger H, et al
    Multi-omics Profiling of T-cell Leukemia and Lymphoma Enables Targeted Therapeutic Discovery.
    Cancer Res. 2025 Oct 30. doi: 10.1158/0008-5472.CAN-25-0881.
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  13. ZWICK M, Zinkel B, Spohr C, Ruckert T, et al
    FLT3-ITD Induces CMTM6 and Enhances Immune Escape in Acute Myeloid Leukemia.
    Cancer Res. 2025 Oct 3. doi: 10.1158/0008-5472.CAN-25-0349.
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    August 2025
  14. SU Y, Li S, Wang L, Wang Y, et al
    Loss of SETD8 Impairs Mitochondrial Homeostasis to Suppress Leukemia Stem Cell Function in t(8;21) Acute Myeloid Leukemia.
    Cancer Res. 2025 Aug 29. doi: 10.1158/0008-5472.CAN-24-3659.
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    May 2025
  15. BAYET M, Fregona V, Bouttier M, Rouzier C, et al
    Modeling the PAX5P80R Mutation Reveals HIF2alpha Activation as a Common Feature and Therapeutic Target in B-Cell Acute Lymphoblastic Leukemia.
    Cancer Res. 2025 May 12. doi: 10.1158/0008-5472.CAN-24-1698.
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  16. CHEN Y, He L, Ianevski A, Nader K, et al
    A Machine Learning-Based Strategy Predicts Selective and Synergistic Drug Combinations for Relapsed Acute Myeloid Leukemia.
    Cancer Res. 2025 May 12. doi: 10.1158/0008-5472.CAN-24-3840.
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    April 2025
  17. HUBBARD AK, Brown DW, Liu J, Chan IC, et al
    Integration of Germline and Somatic Variation Improves Chronic Lymphocytic Leukemia Risk Stratification.
    Cancer Res. 2025 Apr 30. doi: 10.1158/0008-5472.CAN-24-4251.
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    March 2025
  18. ZHOU M, Wu Z, Wei F, Duan C, et al
    SMYD3 Activates Fatty Acid beta-oxidation to Promote Self-Renewal of Leukemia Stem Cells.
    Cancer Res. 2025 Mar 13. doi: 10.1158/0008-5472.CAN-24-2117.
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  19. OROFINO G, Toffalori C, Vago L
    In the Right Place and the Right State: Spatial Crosstalk and Immune State Dictate Leukemia Response to Immunotherapy.
    Cancer Res. 2025 Mar 11. doi: 10.1158/0008-5472.CAN-25-1018.
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    December 2024
  20. CERMAKOVA K, Hodges HC
    Pharmacologic Blockade of a Pioneer Transcription Factor.
    Cancer Res. 2024;84:4124-4125.
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  21. LIU X, Liu Y, Rao Q, Mei Y, et al
    Targeting Fatty Acid Metabolism Abrogates the Differentiation Blockade in Preleukemic Cells.
    Cancer Res. 2024;84:4233-4245.
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    November 2024
  22. ZHAI F, Pan G, Xue L, Cheng C, et al
    PRDM16 Induces Methylation of FLT3 to Promote FLT3-ITD Signaling and Leukemia Progression.
    Cancer Res. 2024 Nov 4. doi: 10.1158/0008-5472.CAN-24-0577.
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    October 2024
  23. LUO Z, Lin C, Yu C, Yuan C, et al
    Targeted Degradation of SOS1 Exhibits Potent Anticancer Activity and Overcomes Resistance in KRAS-Mutant Tumors and BCR-ABL-Positive Leukemia.
    Cancer Res. 2024 Oct 22. doi: 10.1158/0008-5472.CAN-24-1093.
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    September 2024
  24. LUO H, Kharas MG
    Dotting Out AML by Targeting Fibrillarin.
    Cancer Res. 2024;84:2759-2760.
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    August 2024
  25. TORRES-DIZ M, Reglero C, Falkenstein CD, Castro A, et al
    An Alternatively Spliced Gain-of-Function NT5C2 Isoform Contributes to Chemoresistance in Acute Lymphoblastic Leukemia.
    Cancer Res. 2024 Aug 2. doi: 10.1158/0008-5472.CAN-23-3804.
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    July 2024
  26. SCHNEIDER C, Spaink H, Alexe G, Dharia NV, et al
    Targeting the Sodium-Potassium Pump as a Therapeutic Strategy in Acute Myeloid Leukemia.
    Cancer Res. 2024 Jul 18. doi: 10.1158/0008-5472.CAN-23-3560.
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  27. HUANG D, Yu Z, Lu H, Jiang P, et al
    Adhesion GPCR ADGRE2 Maintains Proteostasis to Promote Progression in Acute Myeloid Leukemia.
    Cancer Res. 2024;84:2090-2108.
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    June 2024
  28. POORT VM, Hagelaar R, van Roosmalen MJ, Trabut L, et al
    Transient Differentiation-State Plasticity Occurs During Acute Lymphoblastic Leukemia Initiation.
    Cancer Res. 2024 Jun 17. doi: 10.1158/0008-5472.CAN-24-1090.
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  29. BERTOLI RM, Chung YJ, Difilippantonio MJ, Wokasch A, et al
    The DNA methyltransferase inhibitor 5-aza-4'-thio-2'-deoxycytidine induces C>G transversions and acute lymphoid leukemia development.
    Cancer Res. 2024 Jun 4. doi: 10.1158/0008-5472.CAN-23-2785.
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    April 2024
  30. BOET E, Sarry JE
    Targeting Metabolic Dependencies Fueling the TCA Cycle to Circumvent Therapy Resistance in Acute Myeloid Leukemia.
    Cancer Res. 2024;84:950-952.
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    February 2024
  31. JIN P, Wang X, Jin Q, Zhang Y, et al
    Mutant U2AF1-induced mis-splicing of mRNA translation genes confers resistance to chemotherapy in acute myeloid leukemia.
    Cancer Res. 2024 Feb 28. doi: 10.1158/0008-5472.CAN-23-2543.
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  32. LIU ZS, Sinha S, Bannister M, Song A, et al
    R-Loop Accumulation in Spliceosome Mutant Leukemias Confers Sensitivity to PARP1 Inhibition by Triggering Transcription-Replication Conflicts.
    Cancer Res. 2024;84:577-597.
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    January 2024
  33. MONTEITH AJ, Ramsey HE, Silver AJ, Brown D, et al
    Lactate utilization enables metabolic escape to confer resistance to BET inhibition in acute myeloid leukemia.
    Cancer Res. 2024 Jan 29. doi: 10.1158/0008-5472.CAN-23-0291.
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  34. SU Y, Carter JL, Li X, Fukuda Y, et al
    The imipridone ONC213 targets alpha-ketoglutarate dehydrogenase to induce mitochondrial stress and suppress oxidative phosphorylation in acute myeloid leukemia.
    Cancer Res. 2024 Jan 24. doi: 10.1158/0008-5472.CAN-23-2659.
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  35. RAUCCI F, Vernieri C, Di Tano M, Ligorio F, et al
    Cyclic fasting-mimicking diet plus bortezomib and rituximab is an effective treatment for chronic lymphocytic leukemia.
    Cancer Res. 2024 Jan 19. doi: 10.1158/0008-5472.CAN-23-0295.
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  36. WANG P, Zhang Y, Xiang R, Yang J, et al
    Foretinib is effective in acute myeloid leukemia by inhibiting FLT3 and overcoming secondary mutations that drive resistance to quizartinib and gilteritinib.
    Cancer Res. 2024 Jan 17. doi: 10.1158/0008-5472.CAN-23-1534.
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    December 2023
  37. MAI S, Hodges A, Chen HM, Zhang J, et al
    LILRB3 Modulates Acute Myeloid Leukemia Progression and Acts as an Effective Target for CAR T-cell Therapy.
    Cancer Res. 2023;83:4047-4062.
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  38. XIA L, Liu JY, Yang MY, Zhang XH, et al
    Osimertinib covalently binds to CD34 and eliminates myeloid leukemia stem/progenitor cells.
    Cancer Res. 2023 Dec 14. doi: 10.1158/0008-5472.CAN-23-1632.
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    October 2023
  39. MODI A, Lopez G, Conkrite KL, Su C, et al
    Integrative Genomic Analyses Identify LncRNA Regulatory Networks across Pediatric Leukemias and Solid Tumors.
    Cancer Res. 2023;83:3462-3477.
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    September 2023
  40. ZIERHUT C
    p53 and Innate Immune Signaling in Development and Cancer: Insights from a Hematologic Model of Genome Instability.
    Cancer Res. 2023;83:2807-2808.
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  41. DRESSEL N, Natusch L, Munz CM, Costas Ramon S, et al
    Activation of the cGAS/STING Axis in Genome-Damaged Hematopoietic Cells Does Not Impact Blood Cell Formation or Leukemogenesis.
    Cancer Res. 2023;83:2858-2872.
    >> Share


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