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Articles published in
PLoS Biol
    May 2026
  1. RISTOW LC, Blackburn EE, Jezewski AJ, Lin X, et al
    Cryptococcus neoformans adapts to host CO2 concentrations via metabolic and stress-response remodeling.
    PLoS Biol. 2026;24:e3003561.
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  2. TODD K, Schneider O, Lawrence JM, Aronoff JL, et al
    Environmental redox conditions and strain variation define phenazine-mediated antagonism in co-infecting bacteria.
    PLoS Biol. 2026;24:e3003809.
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    April 2026
  3. DINSHAW KM, Lien KA, Knight M, Ouonkap SVY, et al
    High-throughput characterization of Mycobacterium tuberculosis gene function across diverse conditions.
    PLoS Biol. 2026;24:e3003529.
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    March 2026
  4. HSIEH YP, O'Keefe IP, Wang Z, Sun W, et al
    Magnesium depletion by Candida albicans unleashes two unusual modes of colistin resistance in Pseudomonas aeruginosa with different fitness costs.
    PLoS Biol. 2026;24:e3003673.
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  5. CERCKEL G, Dereinne D, Ledesma-Garcia L, Meuric V, et al
    Non-peptide dysbiosis metabolites reprogram a peptide quorum-sensing receptor to induce sustained predation in beneficial streptococci.
    PLoS Biol. 2026;24:e3003718.
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  6. ALI N, Voorhies M, Rodriguez RA, Sil A, et al
    The Rpd3 histone deacetylase is a critical regulator of temperature-mediated morphogenesis and virulence in the human fungal pathogen Histoplasma.
    PLoS Biol. 2026;24:e3003341.
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    February 2026
  7. ZHOU X, Hilk A, Solis NV, Scott N, et al
    Recurrent mutations in the stress regulator Cap1 reveal a trade-off between azole resistance and oxidative stress response in Candida albicans.
    PLoS Biol. 2026;24:e3003631.
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  8. MASSOL F
    An ecological model of vaginal dysbiosis provides new research leads.
    PLoS Biol. 2026;24:e3003604.
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  9. KAMIYA T, Sofonea MT, France M, Tessandier N, et al
    Resource landscape shapes the composition and stability of the human vaginal microbiota.
    PLoS Biol. 2026;24:e3003575.
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  10. SON YE, Perez-Arques C, Heitman J
    Epimutations driven by RNAi or heterochromatin evoke transient antimicrobial drug resistance in pathogenic Mucor fungi.
    PLoS Biol. 2026;24:e3003598.
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  11. FENG C, Wang G, Wang Y, Gao X, et al
    Microglia sense fungal infections through capsular components from capillary-bound Cryptococcus neoformans via endothelial nucleotide signaling.
    PLoS Biol. 2026;24:e3003642.
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  12. QUINN-BOHMANN N, Carr AV, Gibbons SM
    Metabolic modeling reveals determinants of prebiotic and probiotic treatment efficacy across multiple human intervention trials.
    PLoS Biol. 2026;24:e3003638.
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    January 2026
  13. HEATER S, Voorhies M, Rodriguez RA, English BC, et al
    Rapid gain and loss of a chromosome drives key morphology and virulence phenotypes in the fungal pathogen Histoplasma.
    PLoS Biol. 2026;24:e3003224.
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  14. GOWDY G, Prince A
    How do immunometabolites shape bacterial infections?
    PLoS Biol. 2026;24:e3003585.
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  15. SANG Y, Ren J, Aballay A
    A gut-activated NHR-86-CYP pathway mediates the neuroprotective effects of Enterococcus faecium probiotics in a nematode model of amyotrophic lateral sclerosis.
    PLoS Biol. 2026;24:e3003627.
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    December 2025
  16. VEZINA B, Cooper HB, Barlow CK, Rethoret-Pasty M, et al
    A metabolic atlas of the Klebsiella pneumoniae species complex reveals lineage-specific metabolism and capacity for intra-species co-operation.
    PLoS Biol. 2025;23:e3003559.
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    October 2025
  17. FU C, Xiong EH, Kupczok L, Archambault LS, et al
    Expansion of the functional genomics GRACE library reveals genes relevant for temperature-dependent fitness in Candida albicans.
    PLoS Biol. 2025;23:e3003409.
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    September 2025
  18. MEADE RK, Adefisayo OO, Gontijo MTP, Harris SJ, et al
    Cathepsin Z is a conserved susceptibility factor underlying tuberculosis severity.
    PLoS Biol. 2025;23:e3003377.
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  19. POKHREL A, Chisholm L, Costas A, Pittorino M, et al
    Uropathogenic Escherichia coli proliferate as a coccoid morphotype inside human host cells.
    PLoS Biol. 2025;23:e3003366.
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    August 2025
  20. KRISHNA A, Tonkin-Hill G, Morel-Journel T, Bentley S, et al
    Quantifying the effects of antibiotic resistance and within-host competition on strain fitness in Streptococcus pneumoniae.
    PLoS Biol. 2025;23:e3003300.
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  21. BABU SAIT MR, Jachmann LH, Turkoz G, Milivojevic M, et al
    Genome-wide identification of modulators of Chlamydia trachomatis parasitophorous vacuole stability highlights an important role for sphingolipid supply.
    PLoS Biol. 2025;23:e3003297.
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    July 2025
  22. RAVISHANKAR S, Tuohey SM, Ramos NO, Uchiyama S, et al
    Group B Streptococci lyse endothelial cells to infect the brain in a zebrafish meningitis model.
    PLoS Biol. 2025;23:e3003236.
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  23. YEK KQ, Hodgson ER, Ang CS, Palmer CS, et al
    Legionella effector LpPIP recruits protein phosphatase 1 to the mitochondria to induce dephosphorylation of outer membrane proteins.
    PLoS Biol. 2025;23:e3003261.
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    May 2025
  24. SWISTAK L, Albert M, Valenzuela C, Gokerkucuk EB, et al
    The bacterial type three secretion system induces mechanoporation of vacuolar membranes.
    PLoS Biol. 2025;23:e3003135.
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  25. BILLMYRE RB, Craig CJ, Lyon JW, Reichardt C, et al
    Landscape of essential growth and fluconazole-resistance genes in the human fungal pathogen Cryptococcus neoformans.
    PLoS Biol. 2025;23:e3003184.
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    April 2025
  26. CHOW SH, Jeon Y, Deo P, Yeung ATY, et al
    Staphylococcal toxin PVL ruptures model membranes under acidic conditions through interactions with cardiolipin and phosphatidic acid.
    PLoS Biol. 2025;23:e3003080.
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  27. HU T, Zheng Q, Cao C, Li S, et al
    An agricultural triazole induces genomic instability and haploid cell formation in the human fungal pathogen Candida tropicalis.
    PLoS Biol. 2025;23:e3003062.
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  28. OLANDER M, Rea Vazquez D, Meier K, Singh A, et al
    A multi-strategy antimicrobial discovery approach reveals new ways to treat Chlamydia.
    PLoS Biol. 2025;23:e3003123.
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  29. HOMER CM, Voorhies M, Walcott K, Ochoa E, et al
    Transcriptomic atlas throughout Coccidioides development reveals key phase-enriched transcripts of this important fungal pathogen.
    PLoS Biol. 2025;23:e3003066.
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    February 2025
  30. PONCIN K, McKeand SA, Lavender H, Kurzyp K, et al
    Bacteriocin-like peptides encoded by a horizontally acquired island mediate Neisseria gonorrhoeae autolysis.
    PLoS Biol. 2025;23:e3003001.
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  31. SINGH DND, Roberts ARE, Wang X, Li G, et al
    Toll-1-dependent immune evasion induced by fungal infection leads to cell loss in the Drosophila brain.
    PLoS Biol. 2025;23:e3003020.
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    January 2025
  32. WIELERT I, Kraus-Romer S, Volkmann TE, Craig L, et al
    Pilin antigenic variants impact gonococcal lifestyle and antibiotic tolerance by modulating interbacterial forces.
    PLoS Biol. 2025;23:e3003022.
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    December 2024
  33. MALHOTRA N, Oh S, Finin P, Medrano J, et al
    Environmental fungi target thiol homeostasis to compete with Mycobacterium tuberculosis.
    PLoS Biol. 2024;22:e3002852.
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    September 2024
  34. MAYFIELD JA, Raman S, Ramnarine AK, Mishra VK, et al
    Mycobacteria that cause tuberculosis have retained ancestrally acquired genes for the biosynthesis of chemically diverse terpene nucleosides.
    PLoS Biol. 2024;22:e3002813.
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  35. MASS S, Cohen H, Podicheti R, Rusch DB, et al
    The coral pathogen Vibrio coralliilyticus uses a T6SS to secrete a group of novel anti-eukaryotic effectors that contribute to virulence.
    PLoS Biol. 2024;22:e3002734.
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    August 2024
  36. KRISHNAN N, Priestman M, Uhia I, Charitakis N, et al
    A noninvasive BCG skin challenge model for assessing tuberculosis vaccine efficacy.
    PLoS Biol. 2024;22:e3002766.
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  37. KRISHNAKANT KUSHWAHA S, Wu Y, Leonardo Avila H, Anand A, et al
    Comprehensive blueprint of Salmonella genomic plasticity identifies hotspots for pathogenicity genes.
    PLoS Biol. 2024;22:e3002746.
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  38. MIKI T, Uemura T, Kinoshita M, Ami Y, et al
    Salmonella Typhimurium exploits host polyamines for assembly of the type 3 secretion machinery.
    PLoS Biol. 2024;22:e3002731.
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  39. WOODWARD SE, Neufeld LMP, Pena-Diaz J, Feng W, et al
    Both pathogen and host dynamically adapt pH responses along the intestinal tract during enteric bacterial infection.
    PLoS Biol. 2024;22:e3002761.
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  40. PEDERSEN BH, Simoes FB, Pogrebnyakov I, Welch M, et al
    Metabolic specialization drives reduced pathogenicity in Pseudomonas aeruginosa isolates from cystic fibrosis patients.
    PLoS Biol. 2024;22:e3002781.
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    July 2024
  41. ANTUNES B, Zanchi C, Johnston PR, Maron B, et al
    The evolution of antimicrobial peptide resistance in Pseudomonas aeruginosa is severely constrained by random peptide mixtures.
    PLoS Biol. 2024;22:e3002692.
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  42. YAMAMOTO R, Miki H, Itani A, Takeshita N, et al
    Hyphae of the fungus Aspergillus nidulans demonstrate chemotropism to nutrients and pH.
    PLoS Biol. 2024;22:e3002726.
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    June 2024
  43. RAI LS, Chauvel M, Sanchez H, van Wijlick L, et al
    Metabolic reprogramming during Candida albicans planktonic-biofilm transition is modulated by the transcription factors Zcf15 and Zcf26.
    PLoS Biol. 2024;22:e3002693.
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  44. CHERRAK Y, Salazar MA, Yilmaz K, Kreuzer M, et al
    Commensal E. coli limits Salmonella gut invasion during inflammation by producing toxin-bound siderophores in a tonB-dependent manner.
    PLoS Biol. 2024;22:e3002616.
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  45. COELHO MA, David-Palma M, Shea T, Bowers K, et al
    Comparative genomics of the closely related fungal genera Cryptococcus and Kwoniella reveals karyotype dynamics and suggests evolutionary mechanisms of pathogenesis.
    PLoS Biol. 2024;22:e3002682.
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    May 2024
  46. BLAND DM, Long D, Rosenke R, Hinnebusch BJ, et al
    Yersinia pestis can infect the Pawlowsky glands of human body lice and be transmitted by louse bite.
    PLoS Biol. 2024;22:e3002625.
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    April 2024
  47. MAURE A, Lawaree E, Fiorentino F, Pawlik A, et al
    A host-directed oxadiazole compound potentiates antituberculosis treatment via zinc poisoning in human macrophages and in a mouse model of infection.
    PLoS Biol. 2024;22:e3002259.
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  48. ZAMORA PF, Reidy TG, Armbruster CR, Sun M, et al
    Lytic bacteriophages induce the secretion of antiviral and proinflammatory cytokines from human respiratory epithelial cells.
    PLoS Biol. 2024;22:e3002566.
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  49. ERNST C, Andreassen PR, Giger GH, Nguyen BD, et al
    Direct Salmonella injection into enteroid cells allows the study of host-pathogen interactions in the cytosol with high spatiotemporal resolution.
    PLoS Biol. 2024;22:e3002597.
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    March 2024
  50. GROVER M, Gang SS, Troemel ER, Barkoulas M, et al
    Proteasome inhibition triggers tissue-specific immune responses against different pathogens in C. elegans.
    PLoS Biol. 2024;22:e3002543.
    >> Share


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