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Articles published in
J Med Chem
    June 2021
  1. VAN DER WESTHUYZEN R, Mabhula A, Njaria PM, Muller R, et al
    Benzoheterocyclic Oxime Carbamates Active against Mycobacterium tuberculosis: Synthesis, Structure-Activity Relationship, Metabolism, and Biology Triaging.
    J Med Chem. 2021 Jun 17. doi: 10.1021/acs.jmedchem.1c00707.
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  2. WANG Z, Li J, Benin BM, Yu B, et al
    Lipophilic Ga Complex with Broad-Spectrum Antimicrobial Activity and the Ability to Overcome Gallium Resistance in both Pseudomonas aeruginosa and Staphylococcus aureus.
    J Med Chem. 2021 Jun 17. doi: 10.1021/acs.jmedchem.1c00656.
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  3. NACLERIO GA, Sintim HO
    Starving Bacteria of Iron: A Potential Strategy to Disperse Bacterial Biofilms.
    J Med Chem. 2021;64:7272-7274.
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  4. YANG H, Kundra S, Chojnacki M, Liu K, et al
    A Modular Synthetic Route Involving N-Aryl-2-nitrosoaniline Intermediates Leads to a New Series of 3-Substituted Halogenated Phenazine Antibacterial Agents.
    J Med Chem. 2021;64:7275-7295.
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    May 2021
  5. SUN W, Jian Y, Zhou M, Yao Y, et al
    Selective and Efficient Photoinactivation of Intracellular Staphylococcus aureus and MRSA with Little Accumulation of Drug Resistance: Application of a Ru(II) Complex with Photolabile Ligands.
    J Med Chem. 2021 May 25. doi: 10.1021/acs.jmedchem.0c02257.
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  6. KEOUGH DT, Wun SJ, Baszczynski O, Eng WS, et al
    Helicobacter pylori Xanthine-Guanine-Hypoxanthine Phosphoribosyltransferase-A Putative Target for Drug Discovery against Gastrointestinal Tract Infections.
    J Med Chem. 2021;64:5710-5729.
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  7. ZHANG H, Hsu HC, Kahne SC, Hara R, et al
    Macrocyclic Peptides that Selectively Inhibit the Mycobacterium tuberculosis Proteasome.
    J Med Chem. 2021 May 5. doi: 10.1021/acs.jmedchem.1c00296.
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    April 2021
  8. SHARMA A, De Rosa M, Singla N, Singh G, et al
    Tuberculosis: An Overview of the Immunogenic Response, Disease Progression, and Medicinal Chemistry Efforts in the Last Decade toward the Development of Potential Drugs for Extensively Drug-Resistant Tuberculosis Strains.
    J Med Chem. 2021 Apr 7. doi: 10.1021/acs.jmedchem.0c01833.
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    March 2021
  9. WU Y, Wang B, Lu H, Zhao H, et al
    Identification of Novel Tricyclic Benzo[1,3]oxazinyloxazolidinones as Potent Antibacterial Agents with Excellent Pharmacokinetic Profiles against Drug-Resistant Pathogens.
    J Med Chem. 2021;64:3234-3248.
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    February 2021
  10. AZUAR A, Li Z, Shibu MA, Zhao L, et al
    Poly(hydrophobic amino acid)-Based Self-Adjuvanting Nanoparticles for Group A Streptococcus Vaccine Delivery.
    J Med Chem. 2021 Feb 2. doi: 10.1021/acs.jmedchem.0c01660.
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    January 2021
  11. KANDALE A, Patel K, Hussein WM, Wun SJ, et al
    Analogues of the Herbicide, N-Hydroxy-N-isopropyloxamate, Inhibit Mycobacterium tuberculosis Ketol-Acid Reductoisomerase and Their Prodrugs Are Promising Anti-TB Drug Leads.
    J Med Chem. 2021 Jan 29. doi: 10.1021/acs.jmedchem.0c01919.
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  12. LI Z, Tu J, Han G, Liu N, et al
    Novel Carboline Fungal Histone Deacetylase (HDAC) Inhibitors for Combinational Treatment of Azole-Resistant Candidiasis.
    J Med Chem. 2021;64:1116-1126.
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    December 2020
  13. SHYAM M, Shilkar D, Verma H, Dev A, et al
    The Mycobactin Biosynthesis Pathway: A Prospective Therapeutic Target in the Battle against Tuberculosis.
    J Med Chem. 2020 Dec 29. doi: 10.1021/acs.jmedchem.0c01176.
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  14. KUMAR G, Narayan R, Kapoor S
    Chemical Tools for Illumination of Tuberculosis Biology, Virulence Mechanisms, and Diagnosis.
    J Med Chem. 2020 Dec 13. doi: 10.1021/acs.jmedchem.0c01337.
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    November 2020
  15. SCHEUPLEIN NJ, Bzdyl NM, Kibble EA, Lohr T, et al
    Targeting Protein Folding: A Novel Approach for the Treatment of Pathogenic Bacteria.
    J Med Chem. 2020;63:13355-13388.
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  16. KARAS JA, Carter GP, Howden BP, Turner AM, et al
    Structure-Activity Relationships of Daptomycin Lipopeptides.
    J Med Chem. 2020;63:13266-13290.
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  17. LIU W, Yuan L, Wang S
    Recent Progress in the Discovery of Antifungal Agents Targeting the Cell Wall.
    J Med Chem. 2020;63:12429-12459.
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    October 2020
  18. REHBERG N, Sommer GA, Driessen D, Kruppa M, et al
    Nature-Inspired (di)Azine-Bridged Bisindole Alkaloids with Potent Antibacterial In Vitro and In Vivo Efficacy against Methicillin-Resistant Staphylococcus aureus.
    J Med Chem. 2020 Oct 25. doi: 10.1021/acs.jmedchem.0c00826.
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  19. BASARAB GS, Doig P, Eyermann CJ, Galullo V, et al
    Antibacterial Spiropyrimidinetriones with N-Linked Azole Substituents on a Benzisoxazole Scaffold Targeting DNA Gyrase.
    J Med Chem. 2020;63:11882-11901.
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    September 2020
  20. LIEUTAUD A, Pieri C, Bolla JM, Brunel JM, et al
    New Polyaminoisoprenyl Antibiotics Enhancers against Two Multidrug-Resistant Gram-Negative Bacteria from Enterobacter and Salmonella Species.
    J Med Chem. 2020;63:10496-10508.
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  21. FEI Y, Wu J, An HW, Zhu K, et al
    Identification of New Nitric Oxide-Donating Peptides with Dual Biofilm Eradication and Antibacterial Activities for Intervention of Device-Related Infections.
    J Med Chem. 2020;63:9127-9135.
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  22. ETAYASH H, Pletzer D, Kumar P, Straus SK, et al
    Cyclic Derivative of Host-Defense Peptide IDR-1018 Improves Proteolytic Stability, Suppresses Inflammation, and Enhances In Vivo Activity.
    J Med Chem. 2020;63:9228-9236.
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    August 2020
  23. NAM S, Ham SY, Kwon H, Kim HS, et al
    Discovery and Characterization of Pure RhlR Antagonists against Pseudomonas aeruginosa Infections.
    J Med Chem. 2020;63:8388-8407.
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  24. KONSTANTINOVIC J, Yahiaoui S, Alhayek A, Haupenthal J, et al
    N-Aryl-3-mercaptosuccinimides as Antivirulence Agents Targeting Pseudomonas aeruginosa Elastase and Clostridium Collagenases.
    J Med Chem. 2020;63:8359-8368.
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  25. KAUR J, Cao X, Abutaleb NS, Elkashif A, et al
    Optimization of Acetazolamide-Based Scaffold as Potent Inhibitors of Vancomycin-Resistant Enterococcus.
    J Med Chem. 2020 Aug 11. doi: 10.1021/acs.jmedchem.0c00734.
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  26. RUDDRARAJU KV, Aggarwal D, Niu C, Baker EA, et al
    Highly Potent and Selective N-aryl Oxamic Acid Based Inhibitors for Mycobacterium tuberculosis Protein Tyrosine Phosphatase B (mPTPB).
    J Med Chem. 2020 Aug 5. doi: 10.1021/acs.jmedchem.0c00302.
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    July 2020
  27. HECKER SJ, Reddy KR, Lomovskaya O, Griffith DC, et al
    Discovery of Cyclic Boronic Acid QPX7728, an Ultrabroad-Spectrum Inhibitor of Serine and Metallo-beta-lactamases.
    J Med Chem. 2020;63:7491-7507.
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  28. SABBAH M, Mendes V, Vistal RG, Dias DMG, et al
    Correction to Fragment-Based Design of Mycobacterium tuberculosis InhA Inhibitors.
    J Med Chem. 2020 Jul 22. doi: 10.1021/acs.jmedchem.0c01187.
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  29. ZHAO H, Wang B, Fu L, Li G, et al
    The Discovery of a Conformationally Constrained Oxazolidinone with Improved Safety and Efficacy Profiles for the Treatment of Multidrug-Resistant Tuberculosis.
    J Med Chem. 2020 Jul 15. doi: 10.1021/acs.jmedchem.0c00500.
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  30. BLAKE S, Thanissery R, Rivera AJ, Hixon MS, et al
    Salicylanilide Analog Minimizes Relapse of Clostridioides difficile Infection in Mice.
    J Med Chem. 2020;63:6898-6908.
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  31. YANG T, Zhang T, Guan X, Dong Z, et al
    Tideglusib and its analogs as inhibitors of Staphylococcus aureus SrtA.
    J Med Chem. 2020 Jul 8. doi: 10.1021/acs.jmedchem.0c00803.
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    June 2020
  32. FERNANDES P, Pereira D, Watkins PB, Bertrand D, et al
    Differentiating the Pharmacodynamics and Toxicology of Macrolide and Ketolide Antibiotics.
    J Med Chem. 2020;63:6462-6473.
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  33. MORI M, Stelitano G, Gelain A, Pini E, et al
    Shedding X-ray light on the role of magnesium in the activity of M. tuberculosis salicylate synthase (MbtI) for drug design.
    J Med Chem. 2020 Jun 12. doi: 10.1021/acs.jmedchem.0c00373.
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  34. LIN S, Li H, Tao Y, Liu J, et al
    In Vitro and in Vivo Evaluation of Membrane-Active Flavone Amphiphiles: Semisynthetic Kaempferol-Derived Antimicrobials against Drug-Resistant Gram-Positive Bacteria.
    J Med Chem. 2020;63:5797-5815.
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    May 2020
  35. HAN G, Liu N, Li C, Tu J, et al
    Discovery of Novel Fungal Lanosterol 14alpha-Demethylase (CYP51)/Histone Deacetylase Dual Inhibitors to Treat Azole-Resistant Candidiasis.
    J Med Chem. 2020;63:5341-5359.
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  36. BALABON O, Pitta E, Rogacki MK, Meiler E, et al
    Optimization of Hydantoins as Potent Antimycobacterial Decaprenylphosphoryl-beta-d-Ribose Oxidase (DprE1) Inhibitors.
    J Med Chem. 2020;63:5367-5386.
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    April 2020
  37. MADGE HYR, Sharma H, Hussein WM, Khalil ZG, et al
    Structure-Activity Analysis of Cyclic Multicomponent Lipopeptide Self-Adjuvanting Vaccine Candidates Presenting Group A Streptococcus Antigens.
    J Med Chem. 2020 Apr 29. doi: 10.1021/acs.jmedchem.0c00203.
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  38. L MOURE A, Narula G, Sorrentino F, Bojang A, et al
    A MymA bioactivated thioalkyl-benzoxazole prodrug family active against Mycobacterium tuberculosis.
    J Med Chem. 2020 Apr 10. doi: 10.1021/acs.jmedchem.0c00003.
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  39. MAYANDI V, Xi Q, Leng Goh ET, Koh SK, et al
    Rational Substitution of epsilon-Lysine for alpha-Lysine Enhances the Cell and Membrane Selectivity of Pore-Forming Melittin.
    J Med Chem. 2020;63:3522-3537.
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  40. MAVRIDIS IM, Yannakopoulou K
    Porphyrinoid-Cyclodextrin Assemblies in Biomedical Research: An Update.
    J Med Chem. 2020;63:3391-3424.
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  41. MAKAROV V, Salina E, Reynolds RC, Kyaw Zin PP, et al
    Molecule Property Analyses of Active Compounds for Mycobacterium Tuberculosis.
    J Med Chem. 2020 Apr 7. doi: 10.1021/acs.jmedchem.9b02075.
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  42. SABBAH M, Mendes V, Vistal RG, Dias DM, et al
    Fragment-based design of Mycobacterium tuberculosis InhA inhibitors.
    J Med Chem. 2020 Apr 2. doi: 10.1021/acs.jmedchem.0c00007.
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    March 2020
  43. LIU B, Trout REL, Chu GH, McGarry D, et al
    Discovery of Taniborbactam (VNRX-5133): A Broad-Spectrum Serine- and Metallo-beta-lactamase Inhibitor for Carbapenem-Resistant Bacterial Infections.
    J Med Chem. 2020;63:2789-2801.
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  44. CHOW HY, Po KHL, Gao P, Blasco P, et al
    Methylation of Daptomycin Leading to the Discovery of Kynomycin, a Cyclic Lipodepsipeptide Active against Resistant Pathogens.
    J Med Chem. 2020;63:3161-3171.
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  45. JU Y, He L, Zhou Y, Yang T, et al
    Discovery of Novel Peptidomimetic Boronate ClpP Inhibitors with Noncanonical Enzyme Mechanism as Potent Virulence Blockers in Vitro and in Vivo.
    J Med Chem. 2020;63:3104-3119.
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  46. MOTA F, Ordonez AA, Firth G, Ruiz-Bedoya CA, et al
    Radiotracer Development for Bacterial Imaging.
    J Med Chem. 2020;63:1964-1977.
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  47. GONZALEZ-BELLO C, Rodriguez D, Pernas M, Rodriguez A, et al
    beta-Lactamase Inhibitors To Restore the Efficacy of Antibiotics against Superbugs.
    J Med Chem. 2020;63:1859-1881.
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  48. DENNIS EK, Kim JH, Parkin S, Awuah SG, et al
    Distorted Gold(I)-Phosphine Complexes as Antifungal Agents.
    J Med Chem. 2020;63:2455-2469.
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  49. HUANG DS, LeBlanc EV, Shekhar-Guturja T, Robbins N, et al
    Design and Synthesis of Fungal-Selective Resorcylate Aminopyrazole Hsp90 Inhibitors.
    J Med Chem. 2020;63:2139-2180.
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    February 2020
  50. HUFF LM, Horibata S, Robey RW, Hall MD, et al
    Mycoplasma Infection Mediates Sensitivity of Multidrug-Resistant Cell Lines to Tiopronin: A Cautionary Tale.
    J Med Chem. 2020;63:1434-1439.
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    January 2020
  51. BORTHWICK JA, Alemparte C, Wall I, Whitehurst BC, et al
    Mycobacterium tuberculosis Decaprenylphosphoryl-beta-D-ribose Oxidase inhibitors: expeditious reconstruction of sub-optimal hits into a series with potent in vivo activity.
    J Med Chem. 2020 Jan 10. doi: 10.1021/acs.jmedchem.9b01561.
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  52. PANCHAUD P, Surivet JP, Diethelm S, Blumstein AC, et al
    Optimization of LpxC Inhibitor Lead Compounds Focusing on Efficacy and Formulation for High Dose Intravenous Administration.
    J Med Chem. 2020;63:88-102.
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  53. SURIVET JP, Panchaud P, Specklin JL, Diethelm S, et al
    Discovery of Novel Inhibitors of LpxC Displaying Potent in Vitro Activity against Gram-Negative Bacteria.
    J Med Chem. 2020;63:66-87.
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    December 2019
  54. RYTER K, Ettenger G, Rasheed OK, Buhl C, et al
    Aryl Trehalose Derivatives as Vaccine Adjuvants for Mycobacterium tuberculosis.
    J Med Chem. 2019 Dec 6. doi: 10.1021/acs.jmedchem.9b01598.
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    October 2019
  55. HORSWILL AR, Gordon CP
    Structure-Activity-Relationship Studies of Small Molecule Modulators of the Staphylococcal Accessory Gene Regulator.
    J Med Chem. 2019 Oct 28. doi: 10.1021/acs.jmedchem.9b00798.
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  56. RAJPUT S, McLean KJ, Poddar H, Selvam I, et al
    Structure-activity relationships of cyclo(L-tyrosyl-L-tyrosine) derivatives binding to Mycobacterium tuberculosis CYP121: iodinated analogues promote shift to high-spin adduct.
    J Med Chem. 2019 Oct 16. doi: 10.1021/acs.jmedchem.9b01199.
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    September 2019
  57. ZHAN W, Hsu HC, Morgan T, Ouellette T, et al
    Selective Phenylimidazole-based Inhibitors of the Mycobacterium tuberculosis Proteasome.
    J Med Chem. 2019 Sep 27. doi: 10.1021/acs.jmedchem.9b01187.
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  58. WHITEHOUSE AJ, Libardo MDJ, Kasbekar M, Brear PD, et al
    Targeting of fumarate hydratase from Mycobacterium tuberculosis using allosteric inhibitors with a dimeric-binding mode.
    J Med Chem. 2019 Sep 13. doi: 10.1021/acs.jmedchem.9b01203.
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    August 2019
  59. ASHHURST A, McDonald D, Hanna C, Stanojevic V, et al
    Mucosal vaccination with a self-adjuvanted lipopeptide is immunogenic and protective against Mycobacterium tuberculosis.
    J Med Chem. 2019 Aug 2. doi: 10.1021/acs.jmedchem.9b00832.
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    June 2019
  60. KULKARNI A, Soni I, Kelkar D, Dharmaraja AT, et al
    Chemoproteomics of an Indole-Based Quinone-Epoxide identifies druggable vulnerabilities in Vancomycin Resistant Staphylococcus aureus (VRSA).
    J Med Chem. 2019 Jun 26. doi: 10.1021/acs.jmedchem.9b00774.
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    April 2019
  61. CRESPO RA, Dang Q, Zhou NE, Guthrie LM, et al
    Structure-Guided Drug Design of 6-Substituted Adenosine Analogues as Potent Inhibitors of Mycobacterium tuberculosis Adenosine Kinase.
    J Med Chem. 2019 Apr 19. doi: 10.1021/acs.jmedchem.9b00020.
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    March 2019
  62. ZHANG W, Lun S, Liu LL, Xiao S, et al
    Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis. Part II.
    J Med Chem. 2019 Mar 15. doi: 10.1021/acs.jmedchem.9b00010.
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    February 2019
  63. WANG X, Zeng Y, Sheng L, Larson P, et al
    A Cinchona Alkaloid Antibiotic that Appears to Target ATP Synthase in Streptococcus pneumoniae.
    J Med Chem. 2019 Feb 19. doi: 10.1021/acs.jmedchem.8b01353.
    >> Share

  64. TU J, Li Z, Jiang Y, Ji C, et al
    Discovery of Carboline Derivatives as Potent Antifungal Agents for the Treatment of Cryptococcal Meningitis.
    J Med Chem. 2019 Feb 12. doi: 10.1021/acs.jmedchem.8b01598.
    >> Share

    November 2018
  65. GUARDIA A, Baiget J, Cacho M, Perez A, et al
    Easy-to-Synthesize Spirocyclic Compounds Possess Remarkable In Vivo Activity Against Mycobacterium Tuberculosis.
    J Med Chem. 2018 Nov 20. doi: 10.1021/acs.jmedchem.8b01533.
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  66. KUNKLE T, Abdeen S, Salim N, Ray AM, et al
    Hydroxybiphenylamide GroEL/ES inhibitors are potent antibacterials against planktonic and biofilm forms of Staphylococcus aureus.
    J Med Chem. 2018 Nov 4. doi: 10.1021/acs.jmedchem.8b01293.
    >> Share

  67. MIZAR P, Arya R, Kim T, Cha S, et al
    Total synthesis of Xanthoangelol B and its various fragments: towards inhibition of virulence factor production of Staphylococcus aureus.
    J Med Chem. 2018 Nov 2. doi: 10.1021/acs.jmedchem.8b01012.
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    August 2018
  68. VICKERS C, Silva A, Chakraborty A, Fernandez P, et al
    Structure-based design of MptpB inhibitors that reduce multi-drug-resistant Mycobacterium tuberculosis survival and infection burden in vivo.
    J Med Chem. 2018 Aug 28. doi: 10.1021/acs.jmedchem.8b00832.
    >> Share

    July 2018
  69. ABDEEN S, Kunkle T, Salim N, Ray AM, et al
    Sulfonamido-2-arylbenzoxazole GroEL/ES inhibitors are potent antibacterials against methicillin-resistant Staphylococcus aureus (MRSA).
    J Med Chem. 2018 Jul 30. doi: 10.1021/acs.jmedchem.8b00989.
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    June 2018
  70. CLEGHORN LAT, Ray P, Odingo J, Kumar A, et al
    Identification of Morpholino Thiophenes as Novel Mycobacterium tuberculosis Inhibitors, Targeting QcrB.
    J Med Chem. 2018 Jun 26. doi: 10.1021/acs.jmedchem.8b00172.
    >> Share

    May 2018
  71. CHIKHALE RV, Barmade MA, Murumkar PR, Yadav MR, et al
    An Overview of the Development of DprE1 Inhibitors for Combating the Menace of Tuberculosis.
    J Med Chem. 2018 May 31. doi: 10.1021/acs.jmedchem.8b00281.
    >> Share

  72. CHACKO S, Boshoff HIM, Singh V, Ferraris DM, et al
    Expanding benzoxazole based inosine 5'-monophosphate dehydrogenase (IMPDH) inhibitor structure-activity as potential anti-tuberculosis agents.
    J Med Chem. 2018 May 10. doi: 10.1021/acs.jmedchem.7b01839.
    >> Share

    March 2018
  73. TRAPERO A, Pacitto A, Singh V, Sabbah M, et al
    Fragment-Based Approach to Targeting Inosine-5'-monophosphate Dehydrogenase (IMPDH) from Mycobacterium tuberculosis.
    J Med Chem. 2018 Mar 23. doi: 10.1021/acs.jmedchem.7b01622.
    >> Share

  74. SONG L, Merceron R, Gracia B, Quintana AL, et al
    Structure Guided Lead Generation towards non-chiral M. tuberculosis Thymidylate Kinase Inhibitors.
    J Med Chem. 2018 Mar 6. doi: 10.1021/acs.jmedchem.7b01570.
    >> Share

    February 2018
  75. CAI S, Qiao X, Feng L, Shi N, et al
    Python Cathelicidin CATHPb1 Protects against Multidrug-Resistant Staphylococcal Infections by Antimicrobial-Immunomodulatory Duality.
    J Med Chem. 2018 Feb 21. doi: 10.1021/acs.jmedchem.8b00036.
    >> Share

    January 2018
  76. PARMAR A, Lakshminarayanan R, Iyer A, Mayandi V, et al
    Design and syntheses of highly potent teixobactin analogues against Staphylococcus aureus, Methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococci (VRE) in vitro and in vivo.
    J Med Chem. 2018 Jan 24. doi: 10.1021/acs.jmedchem.7b01634.
    >> Share

  77. ZHANG W, Lun S, Wang SH, Jiang X, et al
    Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors Against Mycobacterium Tuberculosis.
    J Med Chem. 2018 Jan 12. doi: 10.1021/acs.jmedchem.7b01319.
    >> Share

    December 2017
  78. GUAN D, Chen F, Xiong L, Tang F, et al
    Extra sugar on vancomycin: new analogues for combating multidrug-resistant Staphylococcus aureus and vancomycin-resistant Enterococci.
    J Med Chem. 2017 Dec 15. doi: 10.1021/acs.jmedchem.7b01345.
    >> Share

  79. CAMERON AJ, Edwards PJB, Harjes E, Sarojini V, et al
    Tyrocidine A Analogues Bearing the Planar d-Phe-2-Abz Turn Motif: How Conformation Impacts Bioactivity.
    J Med Chem. 2017;60:9565-9574.
    >> Share

  80. MOON SH, Zhang X, Zheng G, Meeker DG, et al
    Novel Linear Lipopeptide Paenipeptins with Potential for Eradicating Biofilms and Sensitizing Gram-Negative Bacteria to Rifampicin and Clarithromycin.
    J Med Chem. 2017;60:9630-9640.
    >> Share

  81. CHOI H, Ham SY, Cha E, Shin Y, et al
    Structure-Activity Relationships of 6- and 8-Gingerol Analogs as Anti-Biofilm Agents.
    J Med Chem. 2017;60:9821-9837.
    >> Share

    October 2017
  82. GOOD JAD, Kulen M, Silver J, Krishnan KS, et al
    Thiazolino 2-pyridone amide isosteres as inhibitors of Chlamydia trachomatis infectivity.
    J Med Chem. 2017 Oct 20. doi: 10.1021/acs.jmedchem.7b00716.
    >> Share

    September 2017
  83. LI X, Hernandez V, Rock FL, Choi W, et al
    Discovery of a Potent and Specific M. tuberculosis Leucyl-tRNA Synthetase Inhibitor: (S)-3-(Aminomethyl)-4-chloro-7-(2-hydroxyethoxy)benzo[c][1,2]oxaborol-1(3H)-ol (GSK656).
    J Med Chem. 2017 Sep 27. doi: 10.1021/acs.jmedchem.7b00631.
    >> Share

  84. BUCHIERI MV, Cimino M, Rebollo-Ramirez S, Beauvineau C, et al
    Nitazoxanide Analogs Require Nitroreduction for Antimicrobial Activity in Mycobacterium smegmatis.
    J Med Chem. 2017;60:7425-7433.
    >> Share

  85. CHEN AY, Thomas PW, Stewart AC, Bergstrom A, et al
    Dipicolinic Acid Derivatives as Inhibitors of New Delhi Metallo-beta-lactamase-1.
    J Med Chem. 2017;60:7267-7283.
    >> Share

  86. ABDEL MONAIM SAH, Ramchuran EJ, El-Faham A, Albericio F, et al
    Converting Teixobactin into a Cationic Antimicrobial Peptide (AMP).
    J Med Chem. 2017;60:7476-7482.
    >> Share


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