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Articles published in
J Clin Invest
    May 2024
  1. BISHU S, Kao JY
    A step closer to understanding how a diet high in simple carbohydrates may cause dysbiosis.
    J Clin Invest. 2024;134:e180001.
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    March 2024
  2. HECHT AL, Harling LC, Friedman ES, Tanes C, et al
    Dietary carbohydrates regulate intestinal colonization and dissemination of Klebsiella pneumoniae.
    J Clin Invest. 2024;134:e174726.
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  3. PEEL JN, Yang R, Le Voyer T, Gervais A, et al
    Neutralizing IFN-gamma autoantibodies are rare and pathogenic in HLA-DRB1*15:02 or 16:02 individuals.
    J Clin Invest. 2024;134:e178263.
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    February 2024
  4. VAN STRAALEN KR, Ma F, Tsou PS, Plazyo O, et al
    Single-cell sequencing reveals Hippo signaling as a driver of fibrosis in hidradenitis suppurativa.
    J Clin Invest. 2024;134:e169225.
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    January 2024
  5. DE SOUZA GONCALVES L, Chu T, Master R, Chhetri PD, et al
    Mg2+ supplementation treats secretory diarrhea in mice by activating calcium-sensing receptor in intestinal epithelial cells.
    J Clin Invest. 2024;134:e171249.
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  6. WEERATUNGA P, Moller DR, Ho LP
    Immune mechanisms of granuloma formation in sarcoidosis and tuberculosis.
    J Clin Invest. 2024;134:e175264.
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    December 2023
  7. ALFANO DN, Miller MJ, Bubeck Wardenburg J
    Endothelial ADAM10 utilization defines a molecular pathway of vascular injury in mice with bacterial sepsis.
    J Clin Invest. 2023;133:e168450.
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    October 2023
  8. KOLESKE BN, Jacobs WR Jr, Bishai WR
    The Mycobacterium tuberculosis genome at 25 years: lessons and lingering questions.
    J Clin Invest. 2023;133:e173156.
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    September 2023
  9. KANJANA K, Strle K, Lochhead RB, Pianta A, et al
    Autoimmunity to synovial extracellular matrix proteins in patients with postinfectious Lyme arthritis.
    J Clin Invest. 2023;133:e161170.
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  10. AWASTHI D, Chopra S, Cho BA, Emmanuelli A, et al
    Inflammatory ER stress responses dictate the immunopathogenic progression of systemic candidiasis.
    J Clin Invest. 2023;133:e167359.
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    August 2023
  11. TANG S, De Jesus AC, Chavez D, Suthakaran S, et al
    Rescue of alveolar wall liquid secretion blocks fatal lung injury by influenza-staphylococcal coinfection.
    J Clin Invest. 2023 Aug 15:e163402. doi: 10.1172/JCI163402.
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  12. ZHU H, Chelysheva I, Cross DL, Blackwell L, et al
    Molecular correlates of vaccine-induced protection against typhoid fever.
    J Clin Invest. 2023;133:e169676.
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    May 2023
  13. LAI R, Gong DN, Williams T, Ogunsola AF, et al
    Host genetic background is a barrier to broadly effective vaccine-mediated protection against tuberculosis.
    J Clin Invest. 2023 May 18:e167762. doi: 10.1172/JCI167762.
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  14. THIRUNAVUKKARASU S, Ahmed M, Rosa BA, Boothby M, et al
    Poly(ADP)ribose polymerase 9 mediates early protection against Mycobacterium tuberculosis infection by regulating type I IFN production.
    J Clin Invest. 2023 May 18:e158630. doi: 10.1172/JCI158630.
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    April 2023
  15. DAI Y, Zhu C, Xiao W, Huang K, et al
    Mycobacterium tuberculosis hijacks host TRIM21- and NCOA4-dependent ferritinophagy to enhance intracellular growth.
    J Clin Invest. 2023;133:e159941.
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    March 2023
  16. ROMBOUTS Y, Neyrolles O
    The fat is in the lysosome: how Mycobacterium tuberculosis tricks macrophages into storing lipids.
    J Clin Invest. 2023;133:e168366.
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  17. DIKS AM, de Graaf H, Teodosio C, Groenland RJ, et al
    Distinct early cellular kinetics in participants protected against colonization upon Bordetella pertussis challenge.
    J Clin Invest. 2023;133:e163121.
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  18. GRASSMANN AA, Tokarz R, Golino C, McLain MA, et al
    BosR and PlzA reciprocally regulate RpoS function to sustain Borrelia burgdorferi in ticks and mammals.
    J Clin Invest. 2023;133:e166710.
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    February 2023
  19. BEDARD M, van der Niet S, Bernard EM, Babunovic GH, et al
    A terpene nucleoside from M. tuberculosis induces lysosomal lipid storage in foamy macrophages.
    J Clin Invest. 2023 Feb 9:e161944. doi: 10.1172/JCI161944.
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    January 2023
  20. SCHWARZ C, Eschenhagen P, Schmidt H, Hohnstein T, et al
    Antigen specificity and cross-reactivity drive functionally diverse anti-Aspergillus fumigatus T cell responses in cystic fibrosis.
    J Clin Invest. 2023 Jan 26:e161593. doi: 10.1172/JCI161593.
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    November 2022
  21. DRUMMOND RA, Desai JV, Hsu AP, Oikonomou V, et al
    Human Dectin-1 deficiency impairs macrophage-mediated defense against phaeohyphomycosis.
    J Clin Invest. 2022;132.
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  22. DANIEL L, Bhattacharyya ND, Counoupas C, Cai Y, et al
    Stromal structure remodeling by B lymphocytes limits T cell activation in lymph nodes of Mycobacterium tuberculosis-infected mice.
    J Clin Invest. 2022;132.
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  23. STROBL J, Mundler V, Muller S, Gindl A, et al
    Tick feeding modulates the human skin immune landscape to facilitate tick-borne pathogen transmission.
    J Clin Invest. 2022;132.
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  24. FISCHER AS, Mullerke S, Arnold A, Heuberger J, et al
    R-spondin/YAP axis promotes gastric oxyntic gland regeneration and Helicobacter pylori-associated metaplasia in mice.
    J Clin Invest. 2022;132.
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    September 2022
  25. LEE IK, Jacome DA, Cho JK, Tu V, et al
    Imaging sensitive and drug-resistant bacterial infection with [11C]-trimethoprim.
    J Clin Invest. 2022;132.
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  26. JACOBS WR JR
    A world without tuberculosis: moving from imagination to reality.
    J Clin Invest. 2022;132.
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  27. JESUS K, Moita LF
    Tetracyclines: four rings to rule infections through resistance and disease tolerance.
    J Clin Invest. 2022;132.
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    August 2022
  28. PILIPONSKY AM, Sharma K, Quach P, Brokaw A, et al
    Mast cell derived factor XIIIA contributes to sexual dimorphic defense against group B Streptococcal infections.
    J Clin Invest. 2022 Aug 25. pii: 157999. doi: 10.1172/JCI157999.
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    July 2022
  29. SHARAN R, Ganatra SR, Singh DK, Cole J, et al
    Isoniazid and rifapentine treatment effectively reduces persistent M. tuberculosis infection in macaque lungs.
    J Clin Invest. 2022 Jul 21. pii: 161564. doi: 10.1172/JCI161564.
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  30. HOLLENHORST MI, Nandigama R, Evers SB, Gamayun I, et al
    Bitter taste signaling in tracheal epithelial brush cells elicits innate immune responses to bacterial infection.
    J Clin Invest. 2022;132.
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    May 2022
  31. ALIZADEH M, Raufman JP
    Gastrointestinal neoplasia: carcinogenic interaction between bile acids and Helicobacter pylori in the stomach.
    J Clin Invest. 2022;132.
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  32. NOTO JM, Piazuelo MB, Shah SC, Romero-Gallo J, et al
    Iron deficiency linked to altered bile acid metabolism promotes Helicobacter pylori-induced inflammation-driven gastric carcinogenesis.
    J Clin Invest. 2022;132.
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    March 2022
  33. ARORA G, Hart T, Fikrig E
    Use of host lipids by the Lyme disease spirochete may lead to biomarkers.
    J Clin Invest. 2022;132.
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  34. GWYNNE PJ, Clendenen LH, Turk SP, Marques AR, et al
    Antiphospholipid autoantibodies in Lyme disease arise after scavenging of host phospholipids by Borrelia burgdorferi.
    J Clin Invest. 2022;132.
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    February 2022
  35. MITSI E, Reine J, Urban BC, Solorzano C, et al
    Streptococcus pneumoniae colonization associates with impaired adaptive immune responses against SARS-CoV-2.
    J Clin Invest. 2022 Feb 9. pii: 157124. doi: 10.1172/JCI157124.
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  36. CHANDRA P, Coullon H, Agarwal M, Goss CW, et al
    Macrophage global metabolomics identifies cholestenone as host/pathogen cometabolite present in human Mycobacterium tuberculosis infection.
    J Clin Invest. 2022;132.
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  37. ZHAO D, Yang F, Wang Y, Li S, et al
    ALK1 signaling is required for the homeostasis of Kupffer cells and prevention of bacterial infection.
    J Clin Invest. 2022;132.
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    January 2022
  38. RUIZ-BEDOYA CA, Mota F, Tucker EW, Mahmud FJ, et al
    High-dose rifampin improves bactericidal activity without increased intracerebral inflammation in animal models of tuberculous meningitis.
    J Clin Invest. 2022 Jan 27. pii: 155851. doi: 10.1172/JCI155851.
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    December 2021
  39. SHARAN R, Ganatra SR, Bucsan AN, Cole J, et al
    Antiretroviral therapy timing impacts latent tuberculosis infection reactivation in a tuberculosis/simian immunodeficiency virus coinfection model.
    J Clin Invest. 2021 Dec 2. pii: 153090. doi: 10.1172/JCI153090.
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    November 2021
  40. SCULLY EP, Bryson BD
    Unlocking the complexity of HIV and Mycobacterium tuberculosis coinfection.
    J Clin Invest. 2021;131.
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  41. PIRAZZINI M, Grinzato A, Corti D, Barbieri S, et al
    Exceptionally potent human monoclonal antibodies are effective for prophylaxis and treatment of tetanus in mice.
    J Clin Invest. 2021;131.
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  42. PASTAR I, Sawaya AP, Marjanovic J, Burgess JL, et al
    Intracellular Staphylococcus aureus triggers pyroptosis and contributes to inhibition of healing due to Perforin-2 suppression.
    J Clin Invest. 2021 Nov 2. pii: 133727. doi: 10.1172/JCI133727.
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    September 2021
  43. LI H, Bradbury JA, Edin ML, Graves JP, et al
    sEH promotes macrophage phagocytosis and lung clearance of Streptococcus pneumoniae.
    J Clin Invest. 2021 Sep 30. pii: 129679. doi: 10.1172/JCI129679.
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  44. WU Y, Wu M, Ming S, Zhan X, et al
    TREM-2 promotes Th1 responses by interacting with the CD3zeta-ZAP70 complex following Mycobacterium tuberculosis infection.
    J Clin Invest. 2021;131.
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    July 2021
  45. SIMMONS JD, Van PT, Stein CM, Chihota V, et al
    Monocyte metabolic transcriptional programs associate with resistance to tuberculin skin test/interferon-gamma release assay conversion.
    J Clin Invest. 2021;131.
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    June 2021
  46. SINGH AK, Netea MG, Bishai WR
    BCG turns 100: its nontraditional uses against viruses, cancer, and immunologic diseases.
    J Clin Invest. 2021;131.
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  47. BARKER KA, Etesami NS, Shenoy AT, Arafa EI, et al
    Lung-resident memory B cells protect against bacterial pneumonia.
    J Clin Invest. 2021;131.
    >> Share

  48. SCHILLER ZA, Rudolph MJ, Toomey JR, Ejemel M, et al
    Blocking Borrelia burgdorferi transmission from infected ticks to nonhuman primates with a human monoclonal antibody.
    J Clin Invest. 2021;131.
    >> Share


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