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Articles published in
J Biol Chem
    December 2025
  1. SIROY A, Sun D, Paul A, Rowland JL, et al
    Oligomerization is Required for Channel Formation of MctB and for Copper Resistance of Mycobacterium tuberculosis.
    J Biol Chem. 2025 Dec 9:111037. doi: 10.1016/j.jbc.2025.111037.
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  2. ROSZKOWSKI EK, Charap S, Montague CR, Sukheja P, et al
    Inhibition of de novo fatty acid synthesis in Mycobacterium tuberculosis.
    J Biol Chem. 2025 Dec 8:111022. doi: 10.1016/j.jbc.2025.111022.
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  3. SEKI K, Senoo A, Nagatoishi S, Yanaka S, et al
    Structural basis for heme binding by the Shr protein from Streptococcus pyogenes.
    J Biol Chem. 2025 Dec 5:111012. doi: 10.1016/j.jbc.2025.111012.
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    November 2025
  4. THAKUR S, Mehra R
    Initiator and elongator tRNA recognition mechanism in Mycobacterium tuberculosis methionyl-tRNA synthetase.
    J Biol Chem. 2025 Nov 14:110939. doi: 10.1016/j.jbc.2025.110939.
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  5. ROY R, Jayasinghe YP, Panda S, Zeden MS, et al
    A S180F substitution in D-alanine aminotransferase confers resistance to beta-chloro-D-alanine in Staphylococcus aureus.
    J Biol Chem. 2025 Nov 11:110931. doi: 10.1016/j.jbc.2025.110931.
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  6. FOLCHER V, Auger R, Louche C, Serror P, et al
    Mechanistic insights into Enterocin C targeting the undecaprenyl phosphate recycling protein BacA.
    J Biol Chem. 2025 Nov 11:110929. doi: 10.1016/j.jbc.2025.110929.
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    October 2025
  7. MOJANAGA OO, Woodman TJ, Lloyd MD, Acharya KR, et al
    Correction: Molecular basis of acyl-CoA ester recognition by alpha-methylacyl-CoA racemase from Mycobacterium tuberculosis.
    J Biol Chem. 2025;301:110790.
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  8. MOJANAGA OO, Woodman TJ, Lloyd MD, Acharya KR, et al
    Structural basis for inhibition of Mycobacterium tuberculosis alpha-methylacyl-CoA racemase by 2-arylthiopropanoyl-CoA inhibitor analogs.
    J Biol Chem. 2025 Oct 22:110848. doi: 10.1016/j.jbc.2025.110848.
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  9. AGARWAL R, Biswas K, Agrawal A, Shankar NN, et al
    SA-XV, a 15-amino acid fragment of host defense peptide S100A12, targets mitochondria and is protective against fungal infections.
    J Biol Chem. 2025;301:110743.
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  10. LIU J, Zhang X, Zhang K, Wang J, et al
    Structure-based identification of salvianolic acid B as an inhibitor targeting Salmonella InvC ATPase.
    J Biol Chem. 2025;301:110722.
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  11. KADOOKA C, Tanaka Y, Sato K, Sato H, et al
    Cgm1 is a beta-galactoside alpha-(1 --> 4)-mannosyltransferase involved in the biosynthesis of capsular glucuronoxylomannogalactan in Cryptococcus neoformans.
    J Biol Chem. 2025;301:110632.
    4)-mannosyltransferase involved in the biosynthesis of capsular glucuronoxylomannogalactan in Cryptococcus neoformans.&body=KADOOKA C, Tanaka Y, Sato K, Sato H, et al. Cgm1 is a beta-galactoside alpha-(1 --> 4)-mannosyltransferase involved in the biosynthesis of capsular glucuronoxylomannogalactan in Cryptococcus neoformans. J Biol Chem. 2025;301:110632. https://pubmed.ncbi.nlm.nih.gov/40876590" ALT="Email" TITLE="Email"> --> >> Share

    August 2025
  12. SPROCH J, Prescott R, Kim HJ, Chaguza C, et al
    Cell targeting by the bi-component leukocidin subunit HlgB drives Staphylococcus aureus pathophysiology.
    J Biol Chem. 2025 Aug 12:110592. doi: 10.1016/j.jbc.2025.110592.
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  13. BAUERNFRIED S, Komar T, Sterle K, Tanzer MC, et al
    Inflammasome-independent IL-1beta activation via staphopain A protease of Staphylococcus aureus.
    J Biol Chem. 2025 Aug 8:110574. doi: 10.1016/j.jbc.2025.110574.
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  14. YUAN M, Gonzalez Montalvo MA, Hu Y, Tuz K, et al
    Repurposing clofazimine as an antibiotic to treat cholera: Identification of cellular and structural targets.
    J Biol Chem. 2025;301:110458.
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    July 2025
  15. MORRISON KM, Agarwal R, Stubbs HE, Yu H, et al
    Sialic Acid Identity Modulates Host Tropism of Sialoglycan-binding Viridans Group Streptococci.
    J Biol Chem. 2025 Jul 30:110540. doi: 10.1016/j.jbc.2025.110540.
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  16. ZHANG R, Yao F, Huang Y, Liu W, et al
    Modeling Mycobacterium tuberculosis Pathogenesis in Lung Epithelial Organoids Reveals Strain-Specific Host Responses and Intercellular Crosstalk.
    J Biol Chem. 2025 Jul 28:110534. doi: 10.1016/j.jbc.2025.110534.
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    June 2025
  17. DAVID MS, Zhu Z, McDonald MR, Badiee M, et al
    Crosstalk between iron and flavins in the opportunistic fungal pathogen Candida albicans.
    J Biol Chem. 2025 Jun 19:110396. doi: 10.1016/j.jbc.2025.110396.
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  18. RUIZ MANZANO A, Jensen D, Galburt EA
    Regulation of Steady State Ribosomal Transcription in Mycobacterium tuberculosis: Intersection of Sigma Subunits, Superhelicity, and Transcription Factors.
    J Biol Chem. 2025 Jun 12:110369. doi: 10.1016/j.jbc.2025.110369.
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  19. RAMOS-LEON F, Ramamurthi KS
    Staphylococcus aureus as an emerging model to study bacterial cell division.
    J Biol Chem. 2025 Jun 6:110343. doi: 10.1016/j.jbc.2025.110343.
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    May 2025
  20. SHERRIER TW, Barth VC, Schifano JM, Greendyk JR, et al
    Targeted removal of the 16S rRNA anti-Shine-Dalgarno sequence by a Mycobacterium tuberculosis MazF toxin.
    J Biol Chem. 2025 May 30:110323. doi: 10.1016/j.jbc.2025.110323.
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  21. MOJANAGA OO, Woodman TJ, Lloyd MD, Acharya KR, et al
    Molecular basis of acyl-CoA ester recognition by alpha-methylacyl-CoA racemase from Mycobacterium tuberculosis.
    J Biol Chem. 2025 May 28:110302. doi: 10.1016/j.jbc.2025.110302.
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  22. MACIUNAS LJ, Rotsides P, D'Lauro EJ, Brady S, et al
    The VanS sensor histidine kinase from type-B vancomycin-resistant enterococci recognizes vancomycin directly.
    J Biol Chem. 2025 May 22:110276. doi: 10.1016/j.jbc.2025.110276.
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    March 2025
  23. GIBLIN SP, McKenna S, Matthews S, Sriskandan S, et al
    The N-terminal ELR(+) motif of the neutrophil attractant CXCL8 confers susceptibility to degradation by the Group A Streptococcal protease, SpyCEP.
    J Biol Chem. 2025 Mar 25:108448. doi: 10.1016/j.jbc.2025.108448.
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  24. OTOMO A, Hui Zhu LG, Okuni Y, Yamamoto M, et al
    ATP synthesis of Enterococcus hirae V-ATPase driven by sodium motive force.
    J Biol Chem. 2025 Mar 19:108422. doi: 10.1016/j.jbc.2025.108422.
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  25. JIN XY, Zhang HQ, Feng Z, Liu H, et al
    Complement-activated fragment Ba functions as an antibacterial protein and mediates immune responses in lower vertebrates.
    J Biol Chem. 2025;301:108278.
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    February 2025
  26. XU Y, Banerjee R, Kasibhatla S, Joshi R, et al
    Differential producibility analysis reveals drug-associated carbon and nitrogen metabolite expressions in Mycobacterium tuberculosis.
    J Biol Chem. 2025 Feb 8:108288. doi: 10.1016/j.jbc.2025.108288.
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    January 2025
  27. LIRA AL, Taskin B, Puy C, Keshari RS, et al
    The physicochemical properties of lipopolysaccharide chemotypes regulate activation of the contact pathway of blood coagulation.
    J Biol Chem. 2025;301:108110.
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  28. WEN X, Bai S, Xiong G, Xiu H, et al
    Inhibition of the neddylation E2 enzyme UBE2M in macrophages protects against E. coli-induced sepsis.
    J Biol Chem. 2025;301:108085.
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  29. BRANGULIS K, Surth V, Marcinkiewicz AL, Akopjana I, et al
    CspZ variant-specific interaction with factor H incorporates a metal site to support Lyme borreliae complement evasion.
    J Biol Chem. 2025;301:108083.
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    December 2024
  30. HE Y, Zalenski N, Stephenson AA, Raper AT, et al
    Conformational transitions of Streptococcus pyogenes Cas9 induced by salt and single-guide RNA binding.
    J Biol Chem. 2024 Dec 21:108120. doi: 10.1016/j.jbc.2024.108120.
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  31. VAN DER VELDEN TT, Kayastha K, Waterham CYJ, Brunle S, et al
    Menaquinone-specific turnover by M. tuberculosis cytochrome bd is redox regulated by the Q-loop disulfide bond.
    J Biol Chem. 2024 Dec 18:108094. doi: 10.1016/j.jbc.2024.108094.
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  32. LIETZ S, Sommer A, Sokolowski LM, Kling C, et al
    Alpha-1 antitrypsin inhibits pertussis toxin.
    J Biol Chem. 2024;300:107950.
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  33. SETT A, Maiti PK, Garg K, Hussain A, et al
    'GGFGGQ' repeats in Hfq of Acinetobacter baumannii are essential for nutrient utilization and virulence.
    J Biol Chem. 2024;300:107895.
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    November 2024
  34. AGUILERA-CORREA JJ, Wei F, Leclercq LD, Tasrini Y, et al
    A dTDP-L-rhamnose 4-epimerase required for glycopeptidolipid biosynthesis in Mycobacterium abscessus.
    J Biol Chem. 2024;300:107852.
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    October 2024
  35. MYERS MJ, Xu Z, Ryan BJ, DeMars ZR, et al
    Molecular insights into the structure and function of the Staphylococcus aureus fatty acid kinase.
    J Biol Chem. 2024 Oct 23:107920. doi: 10.1016/j.jbc.2024.107920.
    >> Share

  36. HERMAN R, Kinniment-Williams B, Rudden M, James AG, et al
    Identification of a Staphylococcal dipeptidase involved in the production of human body odour.
    J Biol Chem. 2024 Oct 23:107928. doi: 10.1016/j.jbc.2024.107928.
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  37. GARTLY SC, Barretto LAF, Cote AMT, Kosowan ZA, et al
    A novel phospholipase A2 is a core component of the typhoid toxin genetic islet.
    J Biol Chem. 2024;300:107758.
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    August 2024
  38. GAUDREAU A, Watson DW, Flannagan RS, Roy P, et al
    Mechanistic insights and in vivo efficacy of thiosemicarbazones against methicillin-resistant Staphylococcus aureus.
    J Biol Chem. 2024 Aug 17:107689. doi: 10.1016/j.jbc.2024.107689.
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    July 2024
  39. HAN J, Balasubramanian I, Flores JA, Bandyopadhyay S, et al
    Intestinal lysozyme engagement of Salmonella Typhimurium stimulates the release of barrier-impairing InvE and Lpp1.
    J Biol Chem. 2024;300:107424.
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    June 2024
  40. KOLESINSKI P, McGowan M, Botteaux A, Smeesters PR, et al
    Conservation of C4BP-binding Sequence Patterns in Streptococcus pyogenes M and Enn Proteins.
    J Biol Chem. 2024 Jun 13:107478. doi: 10.1016/j.jbc.2024.107478.
    >> Share

  41. DUFRESNE K, DiMaggio DA Jr, Maduta CS, Brinsmade SR, et al
    Discovery of an antivirulence compound that targets the Staphylococcus aureus SaeRS two-component system to inhibit toxic shock syndrome toxin-1 production.
    J Biol Chem. 2024 Jun 7:107455. doi: 10.1016/j.jbc.2024.107455.
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  42. KOMATH SS
    To each its own: Mechanisms of cross-talk between GPI biosynthesis and cAMP-protein kinase A signaling in Candida albicans versus Saccharomyces cerevisiae.
    J Biol Chem. 2024 Jun 3:107444. doi: 10.1016/j.jbc.2024.107444.
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  43. SCHNEIDER S, Wirth C, Jank T, Hunte C, et al
    Tyrosine-modifying glycosylation by Yersinia effectors.
    J Biol Chem. 2024;300:107331.
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    May 2024
  44. BARRA ALC, Ullah N, Brognaro H, Gutierrez RF, et al
    Structure and dynamics of the staphylococcal pyridoxal 5-phosphate synthase complex reveal transient interactions at the enzyme interface.
    J Biol Chem. 2024 May 21:107404. doi: 10.1016/j.jbc.2024.107404.
    >> Share

  45. SCHAEFER KG, Russell CM, Pyron RJ, Conley EA, et al
    Polymerization mechanism of the Candida albicans virulence factor candidalysin.
    J Biol Chem. 2024 May 13:107370. doi: 10.1016/j.jbc.2024.107370.
    >> Share

  46. MOTT PD, Zea AH, Lewis J, Mirzalieva O, et al
    Serine deamination by human serine racemase synergizes with antibiotics to curtail the replication of Chlamydia trachomatis.
    J Biol Chem. 2024 May 6:107350. doi: 10.1016/j.jbc.2024.107350.
    >> Share

  47. THOMAS S, Schulz AM, Leong JM, Zeczycki TN, et al
    The molecular determinants of classical pathway complement inhibition by OspEF-related proteins of Borrelia burgdorferi.
    J Biol Chem. 2024;300:107236.
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    April 2024
  48. BANERJEE A, Chakraborty M, Sharma S, Chaturvedi R, et al
    Cyclic AMP binding to a universal stress protein in Mycobacterium tuberculosis is essential for viability.
    J Biol Chem. 2024 Apr 16:107287. doi: 10.1016/j.jbc.2024.107287.
    >> Share

  49. SHEARER HL, Currie MJ, Agnew HN, Trappetti C, et al
    Hypothiocyanous acid reductase is critical for host colonization and infection by Streptococcus pneumoniae.
    J Biol Chem. 2024 Apr 9:107282. doi: 10.1016/j.jbc.2024.107282.
    >> Share

    March 2024
  50. JIANG L, Zhang L, Shu Y, Zhang Y, et al
    Deciphering the role of Enterococcus faecium cytidine deaminase in gemcitabine resistance of gallbladder cancer.
    J Biol Chem. 2024 Mar 14:107171. doi: 10.1016/j.jbc.2024.107171.
    >> Share

  51. ROY S, Bhogapurapu B, Chandra S, Biswas K, et al
    Host antimicrobial peptide S100A12 disrupts the fungal membrane by direct binding and inhibits growth and biofilm formation of Fusarium species.
    J Biol Chem. 2024;300:105701.
    >> Share

  52. AVIVI MY, Touitou N, Rohana H, Lerrer B, et al
    Nucleic acid hybridization-based detection of pathogenic RNA using microscale thermophoresis.
    J Biol Chem. 2024;300:105676.
    >> Share


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