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Articles published in
J Biol Chem
    October 2026
  1. DONG H, Cronan JE
    Suppression of Loss of the FabH 3-Ketoacyl-ACP Synthase III by a KAS II (FabF) Lacking the Active Site Thiol in Enterococcus faecalis.
    J Biol Chem. 2026 Oct 16:113654. doi: 10.1016/j.jbc.2026.113654.
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  2. FATEHI S, Herdendorf TJ, Burklund A, Kvasnica T, et al
    Structural and Kinetic Basis for Selective Inhibition of Canine Myeloperoxidase by Staphylococcal Peroxidase Inhibitor (SPIN) Orthologs.
    J Biol Chem. 2026 Oct 14:113649. doi: 10.1016/j.jbc.2026.113649.
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    September 2026
  3. ZEHNER LM, Edenhart S, Hortschansky P, Rosin M, et al
    The razABCD regulatory island links azalomycin F biosynthesis in Streptomyces iranensis to orsellinic acid production in the fungus Aspergillus nidulans.
    J Biol Chem. 2026 Sep 17:113572. doi: 10.1016/j.jbc.2026.113572.
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  4. YADAV R, Perera YR, Somarathne RP, Himanshi F, et al
    The Mechanism of R2ab-mediated Attachment to Polystyrene Surfaces in Staphylococcus epidermidis.
    J Biol Chem. 2026 Sep 8:113533. doi: 10.1016/j.jbc.2026.113533.
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  5. LI YE, Baron GF, Clemons WM Jr
    Structures of the lipid II flippase from the monoderm pathogen Staphylococcus aureus.
    J Biol Chem. 2026 Sep 5:113516. doi: 10.1016/j.jbc.2026.113516.
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  6. SINGH N, Normile TG, Dasilva D, Pereira de Sa N, et al
    Sphingomyelin synthase 2 regulates host protection conferred by the administration of Cryptococcus neoformans Deltasgl1 strain.
    J Biol Chem. 2026;302:113330.
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    August 2026
  7. GARDINER JH 4TH, Komazin G, Meredith TC
    Reconstitution of the LnsAB lipoprotein N-acylation system complex from Staphylococcus aureus and characterization of substrate preference.
    J Biol Chem. 2026 Aug 11:113434. doi: 10.1016/j.jbc.2026.113434.
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  8. GAO W, Zhou Y, Jiang S, Tang X, et al
    Ergosterol remodeling by the MARVEL protein Mrv6 links genotoxic stress adaptation to virulence in Candida albicans.
    J Biol Chem. 2026 Aug 7:113414. doi: 10.1016/j.jbc.2026.113414.
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  9. QIANQIAN W, Xiaoxiao W, Yongbin W, Jing C, et al
    Bone Marrow Mesenchymal Stem Cell Derived CHI3L1 Protected Against Helicobacter pylori-Induced Gastric Mucosal Damage by Promoting DNA Damage Repair via Regulating CTCF/CPT1A.
    J Biol Chem. 2026 Aug 7:113400. doi: 10.1016/j.jbc.2026.113400.
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    July 2026
  10. HSU WL, Jiao Y, Huang WC, Tran KN, et al
    Engineering internally His-tagged ESX secretion system fusion antigens for tuberculosis nanoparticle vaccines.
    J Biol Chem. 2026 Jul 16:113337. doi: 10.1016/j.jbc.2026.113337.
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    June 2026
  11. ESMAEELI M, Nikolic L, Mazgaj R, Das S, et al
    A closely related pair of superoxide dismutase isozymes from Staphylococcus aureus show distinct stabilities and proton-exchange dynamics.
    J Biol Chem. 2026 Jun 5:113226. doi: 10.1016/j.jbc.2026.113226.
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    May 2026
  12. GAUDREAU A, Beckner MD, Shen C, Du V, et al
    Photochemical modification of two fluorene-based molecules with DNA intercalating and anti-methicillin resistant Staphylococcus aureus activity.
    J Biol Chem. 2026 May 8:113133. doi: 10.1016/j.jbc.2026.113133.
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  13. WILSON GC, Keitsch S, Wilker B, Soddemann M, et al
    Rhinovirus infection promotes suppression of sphingosine and enhanced bacterial infection in cystic fibrosis airways.
    J Biol Chem. 2026;302:111381.
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    April 2026
  14. WU Q, Lu Y, Yuan L, Chen Y, et al
    Small RNA ASpks2 Promote Mycobacterium tuberculosis Survival in Macrophages via Targeting Polyketide Synthase 2.
    J Biol Chem. 2026 Apr 13:111449. doi: 10.1016/j.jbc.2026.111449.
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  15. YANG JK, Huang S, Hou YP, Yuan HF, et al
    Brucella Omp25 activates the unfolded protein response to promote intracellular proliferation and inflammation.
    J Biol Chem. 2026;302:111333.
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    March 2026
  16. DARWIN KH
    Fred Goldberg Machines in the Pathogenesis of Mycobacterium tuberculosis.
    J Biol Chem. 2026 Mar 16:111373. doi: 10.1016/j.jbc.2026.111373.
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  17. KLEETZ J, Grigg JC, Hassan AA, Ibtisam A, et al
    Correction: The biosynthesis of N-acyalated tryptazolone in Mycobacterium tuberculosis and related bacteria.
    J Biol Chem. 2026;302:111272.
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    February 2026
  18. RIEDEL C, Rahkola J, Reichlen M, Ries H, et al
    Identification and characterization of inhibitors of the tuberculosis phosphatase PstP.
    J Biol Chem. 2026 Feb 25:111316. doi: 10.1016/j.jbc.2026.111316.
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  19. HSU HC, Bonnet I, Bryk R, Li H, et al
    Mycobacterium tuberculosis assembles a unique hexameric E2p core of the pyruvate dehydrogenase complex.
    J Biol Chem. 2026 Feb 12:111284. doi: 10.1016/j.jbc.2026.111284.
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  20. FERNANDEZ-PEREZ J, de Vega S, Caaveiro JMM, Nakakido M, et al
    Development of an inhibitory monoclonal nanobody targeting Streptococcus pyogenes siderophore binding protein FtsB.
    J Biol Chem. 2026 Feb 4:111224. doi: 10.1016/j.jbc.2026.111224.
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  21. BHARDWAJ V, Swanson S, Florens L, Washburn MP, et al
    Histone fold domain positioning dictates cotranslational heterodimeric assembly of paralogous TAF12/TAF12L in Candida albicans.
    J Biol Chem. 2026 Feb 4:111239. doi: 10.1016/j.jbc.2026.111239.
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    January 2026
  22. DONEGAN RK, Fu Y, Copeland J, Idga S, et al
    The terminal heme synthetic enzyme, Coproheme Decarboxylase, negatively regulates heme uptake in Mycobacterium tuberculosis.
    J Biol Chem. 2026 Jan 23:111197. doi: 10.1016/j.jbc.2026.111197.
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  23. GUI Z, Qian L, Gao L, Feng Z, et al
    Telomere-protecting protein 1 promotes gastric cancer cell metastasis via enhancing endoplasmic reticulum stress.
    J Biol Chem. 2026;302:110998.
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  24. UNGER N, Liebler-Tenorio EM, Guliev RR, Eiserloh S, et al
    Insights into chlamydial infection at the sub-cellular level using label-free Raman spectroscopy in comparison to electron microscopy.
    J Biol Chem. 2026;302:110940.
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  25. MARILLER C, Letowski P, Chang WT, Lowary TL, et al
    Cell wall arabinogalactan is responsible for Fungitell cross reactivity in nocardiosis.
    J Biol Chem. 2026;302:110900.
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    December 2025
  26. KLEETZ J, Grigg JC, Hassan AA, Ibtisam A, et al
    The biosynthesis of N-acylated tryptazolone in Mycobacterium tuberculosis and related bacteria.
    J Biol Chem. 2025 Dec 20:111079. doi: 10.1016/j.jbc.2025.111079.
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  27. SIROY A, Sun D, Paul A, Rowland JL, et al
    Oligomerization is Required for Channel Formation of MctB and for Copper Resistance of Mycobacterium tuberculosis.
    J Biol Chem. 2025 Dec 9:111037. doi: 10.1016/j.jbc.2025.111037.
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  28. ROSZKOWSKI EK, Charap S, Montague CR, Sukheja P, et al
    Inhibition of de novo fatty acid synthesis in Mycobacterium tuberculosis.
    J Biol Chem. 2025 Dec 8:111022. doi: 10.1016/j.jbc.2025.111022.
    >> Share

  29. SEKI K, Senoo A, Nagatoishi S, Yanaka S, et al
    Structural basis for heme binding by the Shr protein from Streptococcus pyogenes.
    J Biol Chem. 2025 Dec 5:111012. doi: 10.1016/j.jbc.2025.111012.
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    November 2025
  30. THAKUR S, Mehra R
    Initiator and elongator tRNA recognition mechanism in Mycobacterium tuberculosis methionyl-tRNA synthetase.
    J Biol Chem. 2025 Nov 14:110939. doi: 10.1016/j.jbc.2025.110939.
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  31. ROY R, Jayasinghe YP, Panda S, Zeden MS, et al
    A S180F substitution in D-alanine aminotransferase confers resistance to beta-chloro-D-alanine in Staphylococcus aureus.
    J Biol Chem. 2025 Nov 11:110931. doi: 10.1016/j.jbc.2025.110931.
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  32. FOLCHER V, Auger R, Louche C, Serror P, et al
    Mechanistic insights into Enterocin C targeting the undecaprenyl phosphate recycling protein BacA.
    J Biol Chem. 2025 Nov 11:110929. doi: 10.1016/j.jbc.2025.110929.
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    October 2025
  33. MOJANAGA OO, Woodman TJ, Lloyd MD, Acharya KR, et al
    Correction: Molecular basis of acyl-CoA ester recognition by alpha-methylacyl-CoA racemase from Mycobacterium tuberculosis.
    J Biol Chem. 2025;301:110790.
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  34. MOJANAGA OO, Woodman TJ, Lloyd MD, Acharya KR, et al
    Structural basis for inhibition of Mycobacterium tuberculosis alpha-methylacyl-CoA racemase by 2-arylthiopropanoyl-CoA inhibitor analogs.
    J Biol Chem. 2025 Oct 22:110848. doi: 10.1016/j.jbc.2025.110848.
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  35. AGARWAL R, Biswas K, Agrawal A, Shankar NN, et al
    SA-XV, a 15-amino acid fragment of host defense peptide S100A12, targets mitochondria and is protective against fungal infections.
    J Biol Chem. 2025;301:110743.
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  36. LIU J, Zhang X, Zhang K, Wang J, et al
    Structure-based identification of salvianolic acid B as an inhibitor targeting Salmonella InvC ATPase.
    J Biol Chem. 2025;301:110722.
    >> Share

  37. KADOOKA C, Tanaka Y, Sato K, Sato H, et al
    Cgm1 is a beta-galactoside alpha-(1 --> 4)-mannosyltransferase involved in the biosynthesis of capsular glucuronoxylomannogalactan in Cryptococcus neoformans.
    J Biol Chem. 2025;301:110632.
    4)-mannosyltransferase involved in the biosynthesis of capsular glucuronoxylomannogalactan in Cryptococcus neoformans.&body=KADOOKA C, Tanaka Y, Sato K, Sato H, et al. Cgm1 is a beta-galactoside alpha-(1 --> 4)-mannosyltransferase involved in the biosynthesis of capsular glucuronoxylomannogalactan in Cryptococcus neoformans. J Biol Chem. 2025;301:110632. https://pubmed.ncbi.nlm.nih.gov/40876590" ALT="Email" TITLE="Email"> --> >> Share

    August 2025
  38. SPROCH J, Prescott R, Kim HJ, Chaguza C, et al
    Cell targeting by the bi-component leukocidin subunit HlgB drives Staphylococcus aureus pathophysiology.
    J Biol Chem. 2025 Aug 12:110592. doi: 10.1016/j.jbc.2025.110592.
    >> Share

  39. BAUERNFRIED S, Komar T, Sterle K, Tanzer MC, et al
    Inflammasome-independent IL-1beta activation via staphopain A protease of Staphylococcus aureus.
    J Biol Chem. 2025 Aug 8:110574. doi: 10.1016/j.jbc.2025.110574.
    >> Share

  40. YUAN M, Gonzalez Montalvo MA, Hu Y, Tuz K, et al
    Repurposing clofazimine as an antibiotic to treat cholera: Identification of cellular and structural targets.
    J Biol Chem. 2025;301:110458.
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    July 2025
  41. MORRISON KM, Agarwal R, Stubbs HE, Yu H, et al
    Sialic Acid Identity Modulates Host Tropism of Sialoglycan-binding Viridans Group Streptococci.
    J Biol Chem. 2025 Jul 30:110540. doi: 10.1016/j.jbc.2025.110540.
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  42. ZHANG R, Yao F, Huang Y, Liu W, et al
    Modeling Mycobacterium tuberculosis Pathogenesis in Lung Epithelial Organoids Reveals Strain-Specific Host Responses and Intercellular Crosstalk.
    J Biol Chem. 2025 Jul 28:110534. doi: 10.1016/j.jbc.2025.110534.
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    June 2025
  43. DAVID MS, Zhu Z, McDonald MR, Badiee M, et al
    Crosstalk between iron and flavins in the opportunistic fungal pathogen Candida albicans.
    J Biol Chem. 2025 Jun 19:110396. doi: 10.1016/j.jbc.2025.110396.
    >> Share

  44. RUIZ MANZANO A, Jensen D, Galburt EA
    Regulation of Steady State Ribosomal Transcription in Mycobacterium tuberculosis: Intersection of Sigma Subunits, Superhelicity, and Transcription Factors.
    J Biol Chem. 2025 Jun 12:110369. doi: 10.1016/j.jbc.2025.110369.
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  45. RAMOS-LEON F, Ramamurthi KS
    Staphylococcus aureus as an emerging model to study bacterial cell division.
    J Biol Chem. 2025 Jun 6:110343. doi: 10.1016/j.jbc.2025.110343.
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    May 2025
  46. SHERRIER TW, Barth VC, Schifano JM, Greendyk JR, et al
    Targeted removal of the 16S rRNA anti-Shine-Dalgarno sequence by a Mycobacterium tuberculosis MazF toxin.
    J Biol Chem. 2025 May 30:110323. doi: 10.1016/j.jbc.2025.110323.
    >> Share

  47. MOJANAGA OO, Woodman TJ, Lloyd MD, Acharya KR, et al
    Molecular basis of acyl-CoA ester recognition by alpha-methylacyl-CoA racemase from Mycobacterium tuberculosis.
    J Biol Chem. 2025 May 28:110302. doi: 10.1016/j.jbc.2025.110302.
    >> Share

  48. MACIUNAS LJ, Rotsides P, D'Lauro EJ, Brady S, et al
    The VanS sensor histidine kinase from type-B vancomycin-resistant enterococci recognizes vancomycin directly.
    J Biol Chem. 2025 May 22:110276. doi: 10.1016/j.jbc.2025.110276.
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    March 2025
  49. GIBLIN SP, McKenna S, Matthews S, Sriskandan S, et al
    The N-terminal ELR(+) motif of the neutrophil attractant CXCL8 confers susceptibility to degradation by the Group A Streptococcal protease, SpyCEP.
    J Biol Chem. 2025 Mar 25:108448. doi: 10.1016/j.jbc.2025.108448.
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  50. OTOMO A, Hui Zhu LG, Okuni Y, Yamamoto M, et al
    ATP synthesis of Enterococcus hirae V-ATPase driven by sodium motive force.
    J Biol Chem. 2025 Mar 19:108422. doi: 10.1016/j.jbc.2025.108422.
    >> Share

  51. JIN XY, Zhang HQ, Feng Z, Liu H, et al
    Complement-activated fragment Ba functions as an antibacterial protein and mediates immune responses in lower vertebrates.
    J Biol Chem. 2025;301:108278.
    >> Share

    February 2025
  52. XU Y, Banerjee R, Kasibhatla S, Joshi R, et al
    Differential producibility analysis reveals drug-associated carbon and nitrogen metabolite expressions in Mycobacterium tuberculosis.
    J Biol Chem. 2025 Feb 8:108288. doi: 10.1016/j.jbc.2025.108288.
    >> Share

    January 2025
  53. LIRA AL, Taskin B, Puy C, Keshari RS, et al
    The physicochemical properties of lipopolysaccharide chemotypes regulate activation of the contact pathway of blood coagulation.
    J Biol Chem. 2025;301:108110.
    >> Share

  54. WEN X, Bai S, Xiong G, Xiu H, et al
    Inhibition of the neddylation E2 enzyme UBE2M in macrophages protects against E. coli-induced sepsis.
    J Biol Chem. 2025;301:108085.
    >> Share

  55. BRANGULIS K, Surth V, Marcinkiewicz AL, Akopjana I, et al
    CspZ variant-specific interaction with factor H incorporates a metal site to support Lyme borreliae complement evasion.
    J Biol Chem. 2025;301:108083.
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    December 2024
  56. HE Y, Zalenski N, Stephenson AA, Raper AT, et al
    Conformational transitions of Streptococcus pyogenes Cas9 induced by salt and single-guide RNA binding.
    J Biol Chem. 2024 Dec 21:108120. doi: 10.1016/j.jbc.2024.108120.
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  57. VAN DER VELDEN TT, Kayastha K, Waterham CYJ, Brunle S, et al
    Menaquinone-specific turnover by M. tuberculosis cytochrome bd is redox regulated by the Q-loop disulfide bond.
    J Biol Chem. 2024 Dec 18:108094. doi: 10.1016/j.jbc.2024.108094.
    >> Share

  58. LIETZ S, Sommer A, Sokolowski LM, Kling C, et al
    Alpha-1 antitrypsin inhibits pertussis toxin.
    J Biol Chem. 2024;300:107950.
    >> Share

  59. SETT A, Maiti PK, Garg K, Hussain A, et al
    'GGFGGQ' repeats in Hfq of Acinetobacter baumannii are essential for nutrient utilization and virulence.
    J Biol Chem. 2024;300:107895.
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    November 2024
  60. AGUILERA-CORREA JJ, Wei F, Leclercq LD, Tasrini Y, et al
    A dTDP-L-rhamnose 4-epimerase required for glycopeptidolipid biosynthesis in Mycobacterium abscessus.
    J Biol Chem. 2024;300:107852.
    >> Share

    October 2024
  61. MYERS MJ, Xu Z, Ryan BJ, DeMars ZR, et al
    Molecular insights into the structure and function of the Staphylococcus aureus fatty acid kinase.
    J Biol Chem. 2024 Oct 23:107920. doi: 10.1016/j.jbc.2024.107920.
    >> Share

  62. HERMAN R, Kinniment-Williams B, Rudden M, James AG, et al
    Identification of a Staphylococcal dipeptidase involved in the production of human body odour.
    J Biol Chem. 2024 Oct 23:107928. doi: 10.1016/j.jbc.2024.107928.
    >> Share

  63. GARTLY SC, Barretto LAF, Cote AMT, Kosowan ZA, et al
    A novel phospholipase A2 is a core component of the typhoid toxin genetic islet.
    J Biol Chem. 2024;300:107758.
    >> Share

    August 2024
  64. GAUDREAU A, Watson DW, Flannagan RS, Roy P, et al
    Mechanistic insights and in vivo efficacy of thiosemicarbazones against methicillin-resistant Staphylococcus aureus.
    J Biol Chem. 2024 Aug 17:107689. doi: 10.1016/j.jbc.2024.107689.
    >> Share

    July 2024
  65. HAN J, Balasubramanian I, Flores JA, Bandyopadhyay S, et al
    Intestinal lysozyme engagement of Salmonella Typhimurium stimulates the release of barrier-impairing InvE and Lpp1.
    J Biol Chem. 2024;300:107424.
    >> Share

    June 2024
  66. KOLESINSKI P, McGowan M, Botteaux A, Smeesters PR, et al
    Conservation of C4BP-binding Sequence Patterns in Streptococcus pyogenes M and Enn Proteins.
    J Biol Chem. 2024 Jun 13:107478. doi: 10.1016/j.jbc.2024.107478.
    >> Share

  67. DUFRESNE K, DiMaggio DA Jr, Maduta CS, Brinsmade SR, et al
    Discovery of an antivirulence compound that targets the Staphylococcus aureus SaeRS two-component system to inhibit toxic shock syndrome toxin-1 production.
    J Biol Chem. 2024 Jun 7:107455. doi: 10.1016/j.jbc.2024.107455.
    >> Share

  68. KOMATH SS
    To each its own: Mechanisms of cross-talk between GPI biosynthesis and cAMP-protein kinase A signaling in Candida albicans versus Saccharomyces cerevisiae.
    J Biol Chem. 2024 Jun 3:107444. doi: 10.1016/j.jbc.2024.107444.
    >> Share

  69. SCHNEIDER S, Wirth C, Jank T, Hunte C, et al
    Tyrosine-modifying glycosylation by Yersinia effectors.
    J Biol Chem. 2024;300:107331.
    >> Share

    May 2024
  70. BARRA ALC, Ullah N, Brognaro H, Gutierrez RF, et al
    Structure and dynamics of the staphylococcal pyridoxal 5-phosphate synthase complex reveal transient interactions at the enzyme interface.
    J Biol Chem. 2024 May 21:107404. doi: 10.1016/j.jbc.2024.107404.
    >> Share

  71. SCHAEFER KG, Russell CM, Pyron RJ, Conley EA, et al
    Polymerization mechanism of the Candida albicans virulence factor candidalysin.
    J Biol Chem. 2024 May 13:107370. doi: 10.1016/j.jbc.2024.107370.
    >> Share

  72. MOTT PD, Zea AH, Lewis J, Mirzalieva O, et al
    Serine deamination by human serine racemase synergizes with antibiotics to curtail the replication of Chlamydia trachomatis.
    J Biol Chem. 2024 May 6:107350. doi: 10.1016/j.jbc.2024.107350.
    >> Share

  73. THOMAS S, Schulz AM, Leong JM, Zeczycki TN, et al
    The molecular determinants of classical pathway complement inhibition by OspEF-related proteins of Borrelia burgdorferi.
    J Biol Chem. 2024;300:107236.
    >> Share

    April 2024
  74. BANERJEE A, Chakraborty M, Sharma S, Chaturvedi R, et al
    Cyclic AMP binding to a universal stress protein in Mycobacterium tuberculosis is essential for viability.
    J Biol Chem. 2024 Apr 16:107287. doi: 10.1016/j.jbc.2024.107287.
    >> Share

  75. SHEARER HL, Currie MJ, Agnew HN, Trappetti C, et al
    Hypothiocyanous acid reductase is critical for host colonization and infection by Streptococcus pneumoniae.
    J Biol Chem. 2024 Apr 9:107282. doi: 10.1016/j.jbc.2024.107282.
    >> Share

    March 2024
  76. JIANG L, Zhang L, Shu Y, Zhang Y, et al
    Deciphering the role of Enterococcus faecium cytidine deaminase in gemcitabine resistance of gallbladder cancer.
    J Biol Chem. 2024 Mar 14:107171. doi: 10.1016/j.jbc.2024.107171.
    >> Share

  77. ROY S, Bhogapurapu B, Chandra S, Biswas K, et al
    Host antimicrobial peptide S100A12 disrupts the fungal membrane by direct binding and inhibits growth and biofilm formation of Fusarium species.
    J Biol Chem. 2024;300:105701.
    >> Share

  78. AVIVI MY, Touitou N, Rohana H, Lerrer B, et al
    Nucleic acid hybridization-based detection of pathogenic RNA using microscale thermophoresis.
    J Biol Chem. 2024;300:105676.
    >> Share

    October 2023
  79. YAMAZAKI T, Nagatoishi S, Yamawaki T, Nozawa T, et al
    Anti-InlA single-domain antibodies that inhibit the cell invasion of Listeria monocytogenes.
    J Biol Chem. 2023;299:105254.
    >> Share


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