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Articles published in
Antimicrob Agents Chemother
    March 2024
  1. SEGAWA T, Masuda K, Hisatsune J, Ishida-Kuroki K, et al
    Genomic analysis of inter-hospital transmission of vancomycin-resistant Enterococcus faecium sequence type 80 isolated during an outbreak in Hiroshima, Japan.
    Antimicrob Agents Chemother. 2024 Mar 20:e0171623. doi: 10.1128/aac.01716.
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  2. SUN L, Zhuang H, Chen M, Chen Y, et al
    Vancomycin heteroresistance caused by unstable tandem amplifications of the vanM gene cluster on linear conjugative plasmids in a clinical Enterococcus faecium.
    Antimicrob Agents Chemother. 2024 Mar 20:e0115923. doi: 10.1128/aac.01159.
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  3. LYONS MA, Obregon-Henao A, Ramey ME, Bauman AA, et al
    Use of multiple pharmacodynamic measures to deconstruct the Nix-TB regimen in a short-course murine model of tuberculosis.
    Antimicrob Agents Chemother. 2024 Mar 19:e0101023. doi: 10.1128/aac.01010.
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  4. VILLELLAS C, Stevenaert F, Remmerie B, Andries K, et al
    Sub-MIC levels of bedaquiline and clofazimine can select Mycobacterium tuberculosis mutants with increased MIC.
    Antimicrob Agents Chemother. 2024 Mar 12:e0127523. doi: 10.1128/aac.01275.
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  5. HILLIARD JJ, Jakielaszek C, Mannino F, Hossain M, et al
    Efficacy of therapeutically administered gepotidacin in a rabbit model of inhalational anthrax.
    Antimicrob Agents Chemother. 2024;68:e0149723.
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  6. HOSODA K, Koyama N, Shigeno S, Nishimura T, et al
    Mavintramycin A is a promising antibiotic for treating Mycobacterium avium complex infectious disease.
    Antimicrob Agents Chemother. 2024;68:e0091723.
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  7. ZHANG X, Wang Y, Li S, Xie F, et al
    Simulated drug disposition in critically ill patients to evaluate effective PK/PD targets for combating Pseudomonas aeruginosa resistance to meropenem.
    Antimicrob Agents Chemother. 2024;68:e0154123.
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  8. ANDRE C, Van Camp AG, Ung L, Gilmore MS, et al
    Characterization of the resistome and predominant genetic lineages of Gram-positive bacteria causing keratitis.
    Antimicrob Agents Chemother. 2024;68:e0124723.
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  9. DUREJA C, Rutherford JT, Pavel FB, Norseeda K, et al
    In vivo evaluation of Clostridioides difficile enoyl-ACP reductase II (FabK) inhibition by phenylimidazole unveils a promising narrow-spectrum antimicrobial strategy.
    Antimicrob Agents Chemother. 2024;68:e0122223.
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  10. SALILLAS S, Raaijmakers J, Aarnoutse RE, Svensson EM, et al
    Clofazimine as a substitute for rifampicin improves efficacy of Mycobacterium avium pulmonary disease treatment in the hollow-fiber model.
    Antimicrob Agents Chemother. 2024;68:e0115723.
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  11. KOTTOM TJ, Carmona EM, Limper AH
    Characterization of the Pneumocystis jirovecii and Pneumocystis murina phosphoglucomutases (Pgm2s): a potential target for Pneumocystis therapy.
    Antimicrob Agents Chemother. 2024;68:e0075623.
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    February 2024
  12. SARANGI J, Ido A, Ito M, Iinuma C, et al
    Clinical isolates of Streptococcus mitis/oralis-related species with reduced carbapenem susceptibility, harboring amino acid substitutions in penicillin-binding proteins in Japan.
    Antimicrob Agents Chemother. 2024 Feb 28:e0117923. doi: 10.1128/aac.01179.
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  13. OLIVENCA F, Pires D, Silveiro C, Gama B, et al
    Ethambutol and meropenem/clavulanate synergy promotes enhanced extracellular and intracellular killing of Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2024 Feb 27:e0158623. doi: 10.1128/aac.01586.
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  14. LI S-Y, Tyagi S, Soni H, Betoudji F, et al
    Bactericidal and sterilizing activity of novel regimens combining bedaquiline or TBAJ-587 with GSK2556286 and TBA-7371 in a mouse model of tuberculosis.
    Antimicrob Agents Chemother. 2024 Feb 20:e0156223. doi: 10.1128/aac.01562.
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  15. TRUONG-BOLDUC QC, Wang Y, Ferrer-Espada R, Reedy JL, et al
    Staphylococcus aureus AbcA transporter enhances persister formation under beta-lactam exposure.
    Antimicrob Agents Chemother. 2024 Feb 16:e0134023. doi: 10.1128/aac.01340.
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  16. BASSERES E, Eubank TA, Begum K, Alam MJ, et al
    Antibacterial activity of ibezapolstat against antimicrobial-resistant clinical strains of Clostridioides difficile.
    Antimicrob Agents Chemother. 2024 Feb 16:e0162123. doi: 10.1128/aac.01621.
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  17. ERSOY SC, Proctor RA, Rose WE, Abdelhady W, et al
    Sensitizing methicillin-resistant Staphylococcus aureus (MRSA) to cefuroxime: the synergic effect of bicarbonate and the wall teichoic acid inhibitor ticlopidine.
    Antimicrob Agents Chemother. 2024 Feb 13:e0162723. doi: 10.1128/aac.01627.
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  18. ORTIZ DE LA ROSA JM, Martin-Gutierrez G, Casimiro-Soriguer CS, Gimeno-Gascon MA, et al
    C-terminal deletion of RelA protein is suggested as a possible cause of infective endocarditis recurrence with Enterococcus faecium.
    Antimicrob Agents Chemother. 2024 Feb 13:e0108323. doi: 10.1128/aac.01083.
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  19. FLEMING D, Bozyel I, Ozdemir D, Otero JA, et al
    HOCl-producing electrochemical bandage for treating Pseudomonas aeruginosa-infected murine wounds.
    Antimicrob Agents Chemother. 2024;68:e0121623.
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  20. ANTONELLI A, Coppi M, Bonaiuto C, Giovacchini N, et al
    Novel resistance ICEs carrying the bla(FIM-1) metallo-beta-lactamase gene from an ST235 Pseudomonas aeruginosa sublineage.
    Antimicrob Agents Chemother. 2024;68:e0120523.
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  21. KOTTOM TJ, Carmona EM, Limper AH
    Targeting host tyrosine kinase receptor EphA2 signaling via small-molecule ALW-II-41-27 inhibits macrophage pro-inflammatory signaling responses to Pneumocystis carinii beta-glucans.
    Antimicrob Agents Chemother. 2024;68:e0081123.
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  22. MCDONALD RA, Nagy SG, Chambers M, Broberg CA, et al
    Nitric oxide-releasing prodrug for the treatment of complex Mycobacterium abscessus infections.
    Antimicrob Agents Chemother. 2024;68:e0132723.
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  23. PITOUT JDD, Peirano G, Matsumura Y, DeVinney R, et al
    Escherichia coli sequence type 410 with carbapenemases: a paradigm shift within E. coli toward multidrug resistance.
    Antimicrob Agents Chemother. 2024;68:e0133923.
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  24. MARTISCHANG R, Seth-Smith H, Verschuuren TD, Hequet D, et al
    Regional spread of an atypical ESBL-producing Escherichia coli ST131H89 clone among different human and environmental reservoirs in Western Switzerland.
    Antimicrob Agents Chemother. 2024;68:e0092523.
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  25. LEPAK AJ, VanScoy B, Rubino C, Ambrose PG, et al
    In vivo pharmacodynamic characterization of a next-generation polyene, SF001, in the invasive pulmonary aspergillosis mouse model.
    Antimicrob Agents Chemother. 2024 Feb 6:e0163123. doi: 10.1128/aac.01631.
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  26. CARUGATI M, Arif S, Yarrington ME, King LY, et al
    Limitations of antifungal prophylaxis in preventing invasive Candida surgical site infections after liver transplant surgery.
    Antimicrob Agents Chemother. 2024 Feb 1:e0127923. doi: 10.1128/aac.01279.
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    January 2024
  27. AXELL-HOUSE DB, Simar SR, Panesso D, Rincon S, et al
    LiaX is a surrogate marker for cell envelope stress and daptomycin non-susceptibility in Enterococcus faecium.
    Antimicrob Agents Chemother. 2024 Jan 30:e0106923. doi: 10.1128/aac.01069.
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  28. JIANG X, Li D, Sun Z, Lu Y, et al
    Type I BREX system defends against antibiotic-resistant plasmids in Escherichia coli.
    Antimicrob Agents Chemother. 2024 Jan 30:e0112823. doi: 10.1128/aac.01128.
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  29. IOVLEVA A, McElheny CL, Fowler EL, Cober E, et al
    In vitro activity of sulbactam-durlobactam against colistin-resistant and/or cefiderocol-non-susceptible, carbapenem-resistant Acinetobacter baumannii collected in U.S. hospitals.
    Antimicrob Agents Chemother. 2024 Jan 30:e0125823. doi: 10.1128/aac.01258.
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  30. LIU X, Wang Y, Chang W, Dai Y, et al
    AgrA directly binds to the promoter of vraSR and downregulates its expression in Staphylococcus aureus.
    Antimicrob Agents Chemother. 2024 Jan 23:e0089323. doi: 10.1128/aac.00893.
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  31. CHEN F, Yin Y, Chen H, Wang R, et al
    Global genetic diversity and Asian clades evolution: a phylogeographic study of Staphylococcus aureus sequence type 5.
    Antimicrob Agents Chemother. 2024 Jan 23:e0117523. doi: 10.1128/aac.01175.
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  32. TRUONG-BOLDUC QC, Yonker LM, Wang Y, Lawton BG, et al
    NorA efflux pump mediates Staphylococcus aureus response to Pseudomonas aeruginosa pyocyanin toxicity.
    Antimicrob Agents Chemother. 2024 Jan 17:e0100123. doi: 10.1128/aac.01001.
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  33. ALDEJOHANN AM, Menner C, Thielemann N, Martin R, et al
    In vitro activity of ibrexafungerp against clinically relevant echinocandin-resistant Candida strains.
    Antimicrob Agents Chemother. 2024 Jan 11:e0132423. doi: 10.1128/aac.01324.
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  34. PEARLMUTTER BS, Carlisle MG, Wilson BM, Sangwan N, et al
    Pulsed dosing and extended daily dosing of oral vancomycin do not facilitate clearance of Clostridioides difficile colonization in mice.
    Antimicrob Agents Chemother. 2024;68:e0090323.
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  35. WANG X, Chen L, Ruan H, Xiong Z, et al
    Oteseconazole versus fluconazole for the treatment of severe vulvovaginal candidiasis: a multicenter, randomized, double-blinded, phase 3 trial.
    Antimicrob Agents Chemother. 2024;68:e0077823.
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  36. GHASSANI A, Triponney P, Bour M, Plesiat P, et al
    Mutations in genes lpxL1, bamA, and pmrB impair the susceptibility of cystic fibrosis strains of Pseudomonas aeruginosa to murepavadin.
    Antimicrob Agents Chemother. 2024;68:e0129823.
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  37. BREIDENSTEIN EBM, Khan N, Duffy T, Coward C, et al
    SMT-738: a novel small-molecule inhibitor of bacterial lipoprotein transport targeting Enterobacteriaceae.
    Antimicrob Agents Chemother. 2024;68:e0069523.
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  38. BERMUDEZ TA, Brannon JR, Dudipala N, Reasoner S, et al
    Raising the alarm: fosfomycin resistance associated with non-susceptible inner colonies imparts no fitness cost to the primary bacterial uropathogen.
    Antimicrob Agents Chemother. 2024;68:e0080323.
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  39. TERAN N, Egge SL, Phe K, Baptista RP, et al
    The emergence of cefiderocol resistance in Pseudomonas aeruginosa from a heteroresistant isolate during prolonged therapy.
    Antimicrob Agents Chemother. 2024;68:e0100923.
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  40. NOVY E, Abdul-Aziz MH, Cheng V, Burrows F, et al
    Population pharmacokinetics of fluconazole in critically ill patients receiving extracorporeal membrane oxygenation and continuous renal replacement therapy: an ASAP ECMO study.
    Antimicrob Agents Chemother. 2024;68:e0120123.
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  41. GOMIS-FONT MA, Clari MA, Lopez-Causape C, Navarro D, et al
    Emergence of cefiderocol resistance during ceftazidime/avibactam treatment caused by a large genomic deletion, including ampD and piuCD genes, in Pseudomonas aeruginosa.
    Antimicrob Agents Chemother. 2024;68:e0119223.
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  42. KIRKLAND ME, Patfield S, Hughes AC, Hernlem B, et al
    A novel Shiga toxin 2a neutralizing antibody therapeutic with low immunogenicity and high efficacy.
    Antimicrob Agents Chemother. 2024;68:e0059823.
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  43. ARAGAW WW, Negatu DA, Bungard CJ, Dartois VA, et al
    Pharmacological validation of dihydrofolate reductase as a drug target in Mycobacterium abscessus.
    Antimicrob Agents Chemother. 2024;68:e0071723.
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  44. CHEN T, Yao J, Quan K, Xu J, et al
    Repurposing a human acetyl-CoA carboxylase inhibitor firsocostat to treat fungal candidiasis alone and in combination.
    Antimicrob Agents Chemother. 2024;68:e0113123.
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  45. SINGH P, Kumar A, Sharma P, Chugh S, et al
    Identification and optimization of pyridine carboxamide-based scaffold as a drug lead for Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2024 Jan 9:e0076623. doi: 10.1128/aac.00766.
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  46. TAYLOR E, Nailor MD, Feider M, Sullivan S, et al
    Doxycycline versus cephalexin treatment of presumed streptococcal skin and soft tissue infection among adults presenting to the emergency department.
    Antimicrob Agents Chemother. 2024 Jan 3:e0128223. doi: 10.1128/aac.01282.
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    December 2023
  47. RUELAS CASTILLO J, Neupane P, Karanika S, Krug S, et al
    The heme oxygenase-1 metalloporphyrin inhibitor stannsoporfin enhances the bactericidal activity of a novel regimen for multidrug-resistant tuberculosis in a murine model.
    Antimicrob Agents Chemother. 2023 Dec 22:e0104323. doi: 10.1128/aac.01043.
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  48. SINGH S, Gumbo T, Boorgula GD, Thomas TA, et al
    Omadacycline pharmacokinetics/pharmacodynamics and efficacy against multidrug-resistant Mycobacterium tuberculosis in the hollow fiber system model.
    Antimicrob Agents Chemother. 2023 Dec 22:e0108023. doi: 10.1128/aac.01080.
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  49. ALI AM, P Solans B, Hesseling AC, Winckler J, et al
    Pharmacokinetics and cardiac safety of clofazimine in children with rifampicin-resistant tuberculosis.
    Antimicrob Agents Chemother. 2023 Dec 19:e0079423. doi: 10.1128/aac.00794.
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  50. STEMKENS R, Cobussen M, de Laat E, Hoefsloot W, et al
    Successful addition of topical antibiotic treatment after surgery in treatment-refractory nontuberculous mycobacterial skin and soft tissue infections.
    Antimicrob Agents Chemother. 2023;67:e0078823.
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  51. ROEPCKE S, Passarell J, Walker H, Flanagan S, et al
    Population pharmacokinetic modeling and target attainment analyses of rezafungin for the treatment of candidemia and invasive candidiasis.
    Antimicrob Agents Chemother. 2023;67:e0091623.
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  52. NGUYEN DC, Buettner AM, Dousa KM
    Case Commentary: Another prong of attack? Topical antibiotic instillation with negative pressure wound therapy for nontuberculous mycobacterial skin and soft tissue infections.
    Antimicrob Agents Chemother. 2023;67:e0104823.
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  53. ROHANI R, Yarnold PR, Scheetz MH, Neely MN, et al
    Individual meropenem epithelial lining fluid and plasma PK/PD target attainment.
    Antimicrob Agents Chemother. 2023;67:e0072723.
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  54. KADO J, Salman S, Hla TK, Enkel S, et al
    Subcutaneous infusion of high-dose benzathine penicillin G is safe, tolerable, and suitable for less-frequent dosing for rheumatic heart disease secondary prophylaxis: a phase 1 open-label population pharmacokinetic study.
    Antimicrob Agents Chemother. 2023;67:e0096223.
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  55. LERMINIAUX N, Mitchell R, Bartoszko J, Davis I, et al
    Plasmid genomic epidemiology of bla(KPC) carbapenemase-producing Enterobacterales in Canada, 2010-2021.
    Antimicrob Agents Chemother. 2023;67:e0086023.
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  56. FERNANDEZ LEDESMA B, Mendoza-Palomar N, Melendo Perez S, Fernandez-Polo A, et al
    Isavuconazole use and TDM in real-world pediatric practice.
    Antimicrob Agents Chemother. 2023;67:e0082923.
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  57. COBIAN GUEMES AG, Ghatbale P, Blanc AN, Morgan CJ, et al
    Jumbo phages are active against extensively drug-resistant eyedrop-associated Pseudomonas aeruginosa infections.
    Antimicrob Agents Chemother. 2023;67:e0065423.
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  58. SASONI N, Caracciolo B, Cabeza MS, Gamarra S, et al
    Antifungal susceptibility testing following the CLSI M27 document, along with the measurement of MFC/MIC ratio, could be the optimal approach to detect amphotericin B resistance in Clavispora (Candida) lusitaniae. Susceptibility patterns of contempora
    Antimicrob Agents Chemother. 2023 Dec 12:e0096823. doi: 10.1128/aac.00968.
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  59. JAROMIN A, Zarnowski R, Markowski A, Zagorska A, et al
    Liposomal formulation of a new antifungal hybrid compound provides protection against Candida auris in the ex vivo skin colonization model.
    Antimicrob Agents Chemother. 2023 Dec 11:e0095523. doi: 10.1128/aac.00955.
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  60. LIU S, Huang Y, Jensen S, Laman P, et al
    Molecular physiological characterization of the dynamics of persister formation in Staphylococcus aureus.
    Antimicrob Agents Chemother. 2023 Dec 5:e0085023. doi: 10.1128/aac.00850.
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  61. HAN D, Ji Y, Yang S, Song P, et al
    Therapeutic effect of iturin A on Candida albicans oral infection and its pathogenic factors.
    Antimicrob Agents Chemother. 2023 Dec 5:e0094823. doi: 10.1128/aac.00948.
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  62. PANDEY S, Vilcheze C, Werngren J, Bainomugisa A, et al
    Loss-of-function mutations in ndh do not confer delamanid, ethionamide, isoniazid, or pretomanid resistance in Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2023 Dec 1:e0109623. doi: 10.1128/aac.01096.
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    November 2023
  63. ZHAO J, Pu D, Li Z, Liu X, et al
    In vitro activity of cefiderocol, a siderophore cephalosporin, against carbapenem-resistant hypervirulent Klebsiella pneumoniae in China.
    Antimicrob Agents Chemother. 2023 Nov 28:e0073523. doi: 10.1128/aac.00735.
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  64. JIAO F, Bao Y, Li M, Zhang Y, et al
    Unraveling the mechanism of ceftaroline-induced allosteric regulation in penicillin-binding protein 2a: insights for novel antibiotic development against methicillin-resistant Staphylococcus aureus.
    Antimicrob Agents Chemother. 2023 Nov 16:e0089523. doi: 10.1128/aac.00895.
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  65. VAN DER LAAN LE, Garcia-Prats AJ, McIlleron H, Abdelwahab MT, et al
    Optimizing dosing of the cycloserine pro-drug terizidone in children with rifampicin-resistant tuberculosis.
    Antimicrob Agents Chemother. 2023 Nov 16:e0061123. doi: 10.1128/aac.00611.
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  66. SVISHCHUK J, Ebbert K, Waddell B, Izydorczyk C, et al
    Epidemiology and impact of methicillin-sensitive Staphylococcus aureus with beta-lactam antibiotic inoculum effects in adults with cystic fibrosis.
    Antimicrob Agents Chemother. 2023 Nov 15:e0013623. doi: 10.1128/aac.00136.
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  67. LANNI F, Antilus Sainte R, Hansen M Jr, Parigi P, et al
    A preclinical model of TB meningitis to determine drug penetration and activity at the sites of disease.
    Antimicrob Agents Chemother. 2023 Nov 15:e0067123. doi: 10.1128/aac.00671.
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  68. ALMEIDA D, Li S-Y, Lee J, Hafkin B, et al
    Contezolid can replace linezolid in a novel combination with bedaquiline and pretomanid in a murine model of tuberculosis.
    Antimicrob Agents Chemother. 2023 Nov 15:e0078923. doi: 10.1128/aac.00789.
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  69. DIAZ-GARCIA J, Machado M, Alcala L, Reigadas E, et al
    Trends in antifungal resistance in Candida from a multicenter study conducted in Madrid (CANDIMAD study): fluconazole-resistant C. parapsilosis spreading has gained traction in 2022.
    Antimicrob Agents Chemother. 2023;67:e0098623.
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  70. CASADO A, Gimeno A, Aguilar-Guisado M, Garcia M, et al
    Safety of early oral ambulatory treatment of adult patients with bloodstream infections discharged from the emergency department.
    Antimicrob Agents Chemother. 2023;67:e0078023.
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  71. RUIZ VH, Fratoni A, Nicolau DP, Kuti JL, et al
    In vitro activity of imipenem/relebactam against Pseudomonas aeruginosa isolated from patients with cystic fibrosis.
    Antimicrob Agents Chemother. 2023;67:e0092023.
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  72. HARDY ME, Kenney RM, Tibbetts RJ, Shallal AB, et al
    Leveraging stewardship to promote ceftriaxone use in severe infections with low- and no-risk AmpC Enterobacterales.
    Antimicrob Agents Chemother. 2023;67:e0082623.
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  73. EL GHALI A, Stamper K, Kunz Coyne AJ, Holger D, et al
    Ciprofloxacin in combination with bacteriophage cocktails against multi-drug resistant Pseudomonas aeruginosa in ex vivo simulated endocardial vegetation models.
    Antimicrob Agents Chemother. 2023;67:e0072823.
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  74. SCHILDKRAUT JA, Raaijmakers J, Aarnoutse R, Hoefsloot W, et al
    The role of rifampicin within the treatment of Mycobacterium avium pulmonary disease.
    Antimicrob Agents Chemother. 2023;67:e0087423.
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  75. LIM SY, Kwon HJ, Lee YW, Sung H, et al
    Routine ophthalmologic examination in Klebsiella pneumoniae bacteremia is not necessary: incidence of and risk factors for ocular involvement.
    Antimicrob Agents Chemother. 2023;67:e0082223.
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  76. HOLGER DJ, El Ghali A, Bhutani N, Lev KL, et al
    Phage-antibiotic combinations against multidrug-resistant Pseudomonas aeruginosa in in vitro static and dynamic biofilm models.
    Antimicrob Agents Chemother. 2023;67:e0057823.
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  77. HALL RG 2ND, Liu S, Putnam WC, Kallem R, et al
    Optimizing anidulafungin exposure across a wide adult body size range.
    Antimicrob Agents Chemother. 2023;67:e0082023.
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  78. JUNG J, Chong YP, Lee HJ, Shim TS, et al
    Comparison of treatment outcomes between intermittent and daily regimens in non-cavitary nodular bronchiectatic-type Mycobacterium avium complex pulmonary disease in relation to sputum smear results: a retrospective cohort study.
    Antimicrob Agents Chemother. 2023;67:e0100323.
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  79. ERB T, Mihai S, Strauss R, Herbst L, et al
    beta-(1-->3)-D-glucan- and mannan-guided early termination of antifungal therapy in ICU patients: a randomized controlled study.
    Antimicrob Agents Chemother. 2023;67:e0072523.
    3)-D-glucan- and mannan-guided early termination of antifungal therapy in ICU patients: a randomized controlled study.&body=ERB T, Mihai S, Strauss R, Herbst L, et al. beta-(1-->3)-D-glucan- and mannan-guided early termination of antifungal therapy in ICU patients: a randomized controlled study. Antimicrob Agents Chemother. 2023;67:e0072523. https://www.ncbi.nlm.nih.gov/m/pubmed/37823695" ALT="Email" TITLE="Email"> --> >> Share

  80. MUSICK WL
    Case Commentary: An espresso, a free puppy, and multidrug-resistant Campylobacter.
    Antimicrob Agents Chemother. 2023;67:e0075223.
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  81. BAO X, Goeteyn E, Crabbe A, Coenye T, et al
    Effect of malate on the activity of ciprofloxacin against Pseudomonas aeruginosa in different in vivo and in vivo-like infection models.
    Antimicrob Agents Chemother. 2023;67:e0068223.
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  82. HUANG L, Li Y, Xu C, Zhou M, et al
    A novel virulence plasmid encoding yersiniabactin, salmochelin, and RmpADC from hypervirulent Klebsiella pneumoniae of distinct genetic backgrounds.
    Antimicrob Agents Chemother. 2023;67:e0093523.
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  83. LI Y, Fang L, Dong M, Cai H, et al
    bla (KPC-2) overexpression and bla (GES-5) carriage as major imipenem/relebactam resistance mechanisms in Pseudomonas aeruginosa high-risk clones ST463 and ST235, respectively, in China.
    Antimicrob Agents Chemother. 2023;67:e0067523.
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  84. TIAN Z-X, Wang Y-P
    Identification of cpxS mutational resistome in Pseudomonas aeruginosa.
    Antimicrob Agents Chemother. 2023;67:e0092123.
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  85. MENSAH E, Fourie PB, Peters RPH
    Antimicrobial effects of Medicines for Malaria Venture Pathogen Box compounds on strains of Neisseria gonorrhoeae.
    Antimicrob Agents Chemother. 2023;67:e0034823.
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    October 2023
  86. JIANG S, Chen M, Zhang J, Ba X, et al
    Profiling daptomycin resistance among diverse methicillin-resistant Staphylococcus aureus lineages in China.
    Antimicrob Agents Chemother. 2023 Oct 30:e0056323. doi: 10.1128/aac.00563.
    >> Share

  87. VAN SCHALKWYK M, Bekker A, Decloedt E, Wang J, et al
    Pharmacokinetics and safety of first-line tuberculosis drugs rifampin, isoniazid, ethambutol, and pyrazinamide during pregnancy and postpartum: results from IMPAACT P1026s.
    Antimicrob Agents Chemother. 2023 Oct 26:e0073723. doi: 10.1128/aac.00737.
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  88. XIE YL, Modi N, Handler D, Yu S, et al
    Simplified urine-based method to detect rifampin underexposure in adults with tuberculosis: a prospective diagnostic accuracy study.
    Antimicrob Agents Chemother. 2023 Oct 25:e0093223. doi: 10.1128/aac.00932.
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  89. EL GHALI A, Morrisette T, Alosaimy S, Lucas K, et al
    Long-term evaluation of clinical success and safety of omadacycline in nontuberculous mycobacteria infections: a retrospective, multicenter cohort of real-world health outcomes.
    Antimicrob Agents Chemother. 2023;67:e0082423.
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  90. MUNZEN ME, Reguera Gomez M, Hamed MF, Enriquez V, et al
    Palmitoylethanolamide shows limited efficacy in controlling cerebral cryptococcosis in vivo.
    Antimicrob Agents Chemother. 2023;67:e0045923.
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  91. GIAMBERARDINO CD, Tenor JL, Toffaletti DL, Palmucci JR, et al
    Pharmacodynamics of ATI-2307 in a rabbit model of cryptococcal meningoencephalitis.
    Antimicrob Agents Chemother. 2023;67:e0081823.
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  92. SNYDMAN DR, McDermott LA, Thorpe CM, Goldstein EJC, et al
    A US-based national surveillance study for the susceptibility and epidemiology of Clostridioides difficile isolates with special reference to ridinilazole: 2020-2021.
    Antimicrob Agents Chemother. 2023;67:e0034923.
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  93. ALLAIN M, Maherault AC, Gachet B, Martinez C, et al
    Dissemination of IncI plasmid encoding bla (CTX-M-1) is not hampered by its fitness cost in the pig's gut.
    Antimicrob Agents Chemother. 2023;67:e0011123.
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  94. DEROCHE L, Aranzana-Climent V, Rozenholc A, Prouvensier L, et al
    Characterization of Pseudomonas aeruginosa resistance to ceftolozane-tazobactam due to ampC and/or ampD mutations observed during treatment using semi-mechanistic PKPD modeling.
    Antimicrob Agents Chemother. 2023;67:e0048023.
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  95. AUBRY R, Buyck J, Prouvensier L, Decousser J-W, et al
    An improved PKPD modeling approach to characterize the pharmacodynamic interaction over time between ceftazidime/avibactam and colistin from in vitro time-kill experiments against multidrug-resistant Klebsiella pneumoniae isolates.
    Antimicrob Agents Chemother. 2023;67:e0030123.
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  96. HIGGS C, Kumar LS, Stevens K, Strachan J, et al
    Comparison of contemporary invasive and non-invasive Streptococcus pneumoniae isolates reveals new insights into circulating anti-microbial resistance determinants.
    Antimicrob Agents Chemother. 2023 Oct 12:e0078523. doi: 10.1128/aac.00785.
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  97. LAU JZ, Kuo SH, Belo Y, Malach E, et al
    Antibacterial efficacy of an ultra-short palmitoylated random peptide mixture in mouse models of infection by carbapenem-resistant Klebsiella pneumoniae.
    Antimicrob Agents Chemother. 2023 Oct 11:e0057423. doi: 10.1128/aac.00574.
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  98. KUHBACHER A, Merschak P, Haas H, Liebl M, et al
    The cytochrome P450 reductase CprA is a rate-limiting factor for Cyp51A-mediated azole resistance in Aspergillus fumigatus.
    Antimicrob Agents Chemother. 2023 Oct 10:e0091823. doi: 10.1128/aac.00918.
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  99. RAMEY ME, Kaya F, Bauman AA, Massoudi LM, et al
    Drug distribution and efficacy of the DprE1 inhibitor BTZ-043 in the C3HeB/FeJ mouse tuberculosis model.
    Antimicrob Agents Chemother. 2023 Oct 4:e0059723. doi: 10.1128/aac.00597.
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    September 2023
  100. STEMKENS R, Jager V, Dawson R, Diacon AH, et al
    Drug interaction potential of high-dose rifampicin in patients with pulmonary tuberculosis.
    Antimicrob Agents Chemother. 2023 Sep 28:e0068323. doi: 10.1128/aac.00683.
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  101. AGUILERA-CORREA JJ, Boudehen YM, Kremer L
    Characterization of Mycobacterium abscessus colony-biofilms based on bi-dimensional images.
    Antimicrob Agents Chemother. 2023;67:e0040223.
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  102. XIE M, Ganapathy US, Lan T, Osiecki P, et al
    ADP-ribosylation-resistant rifabutin analogs show improved bactericidal activity against drug-tolerant M. abscessus in caseum surrogate.
    Antimicrob Agents Chemother. 2023;67:e0038123.
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  103. MIRON-OCAMPO A, Beattie SR, Guin S, Conway T, et al
    CWHM-974 is a fluphenazine derivative with improved antifungal activity against Candida albicans due to reduced susceptibility to multidrug transporter-mediated resistance mechanisms.
    Antimicrob Agents Chemother. 2023 Sep 13:e0056723. doi: 10.1128/aac.00567.
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  104. HAYAKAWA K, Matsumura Y, Uemura K, Tsuzuki S, et al
    Effectiveness of cefmetazole versus meropenem for invasive urinary tract infections caused by extended-spectrum beta-lactamase-producing Escherichia coli.
    Antimicrob Agents Chemother. 2023 Sep 13:e0051023. doi: 10.1128/aac.00510.
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  105. NGUYEN HT, Venter H, Woolford L, Young KA, et al
    Oral administration of a 2-aminopyrimidine robenidine analogue (NCL195) significantly reduces Staphylococcus aureus infection and reduces Escherichia coli infection in combination with sub-inhibitory colistin concentrations in a bioluminescent mouse m
    Antimicrob Agents Chemother. 2023 Sep 11:e0042423. doi: 10.1128/aac.00424.
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  106. PODOLL JD, Rosen E, Wang W, Gao Y, et al
    A small-molecule membrane fluidizer re-sensitizes methicillin-resistant Staphylococcus aureus (MRSA) to beta-lactam antibiotics.
    Antimicrob Agents Chemother. 2023 Sep 8:e0005123. doi: 10.1128/aac.00051.
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  107. MEIKLE V, Zhang L, Niederweis M
    Intricate link between siderophore secretion and drug efflux in Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2023 Sep 7:e0162922. doi: 10.1128/aac.01629.
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  108. HENAO-MARTINEZ AF, Chastain DB, Thompson GR 3rd
    Treatment pathways, switches, and inappropriate treatment during invasive pulmonary aspergillosis: real-world experiences from a global research network study.
    Antimicrob Agents Chemother. 2023 Sep 6:e0072123. doi: 10.1128/aac.00721.
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  109. GIULIERI SG
    Case Commentary: The hidden side of oxacillin resistance in Staphylococcus aureus.
    Antimicrob Agents Chemother. 2023 Sep 1:e0071623. doi: 10.1128/aac.00716.
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    August 2023
  110. ARCARI G, Polani R, Santilli S, Capitani V, et al
    Multiplicity of bla(KPC) Genes and pKpQIL Plasmid Plasticity in the Development of Ceftazidime-Avibactam and Meropenem Coresistance in Klebsiella pneumoniae Sequence Type 307.
    Antimicrob Agents Chemother. 2023;67:e0036823.
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  111. TAIT JR, Harper M, Cortes-Lara S, Rogers KE, et al
    Ceftolozane-Tazobactam against Pseudomonas aeruginosa Cystic Fibrosis Clinical Isolates in the Hollow-Fiber Infection Model: Challenges Imposed by Hypermutability and Heteroresistance.
    Antimicrob Agents Chemother. 2023;67:e0041423.
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  112. ALMANGOUR TA, Ghonem L, Alassiri D, Aljurbua A, et al
    Ceftolozane-Tazobactam Versus Ceftazidime-Avibactam for the Treatment of Infections Caused by Multidrug-Resistant Pseudomonas aeruginosa: a Multicenter Cohort Study.
    Antimicrob Agents Chemother. 2023;67:e0040523.
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  113. EGGE SL, Lewis JS 2nd, Hakki M
    Case Commentary: Successful Use of Cefepime/Zidebactam (WCK 5222) as a Salvage Therapy for the Treatment of Disseminated Extensively Drug-Resistant New Delhi Metallo-beta-Lactamase-Producing Pseudomonas aeruginosa Infection in an Adult Patient with Ac
    Antimicrob Agents Chemother. 2023;67:e0066323.
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  114. WALTER ND, Ernest JP, Dide-Agossou C, Bauman AA, et al
    Lung microenvironments harbor Mycobacterium tuberculosis phenotypes with distinct treatment responses.
    Antimicrob Agents Chemother. 2023 Aug 11:e0028423. doi: 10.1128/aac.00284.
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    July 2023
  115. BONILLA-MORENO M, Torrecillas M, Laporte-Amargos J, Gonzalez-Diaz A, et al
    Development of Meropenem Resistance in a Multidrug-Resistant Campylobacter coli Strain Causing Recurrent Bacteremia in a Hematological Malignancy Patient.
    Antimicrob Agents Chemother. 2023;67:e0027223.
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  116. TIRLANGI PK, Wanve BS, Dubbudu RR, Yadav BS, et al
    Successful Use of Cefepime-Zidebactam (WCK 5222) as a Salvage Therapy for the Treatment of Disseminated Extensively Drug-Resistant New Delhi Metallo-beta-Lactamase-Producing Pseudomonas aeruginosa Infection in an Adult Patient with Acute T-Cell Leukem
    Antimicrob Agents Chemother. 2023;67:e0050023.
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  117. WANGCHINDA W, Pogue JM
    Case Commentary: When Voldemort Meets Sauron: Treatment Considerations for Emerging Dual-Carbapenemase-Producing Extensively Drug-Resistant Pseudomonas aeruginosa.
    Antimicrob Agents Chemother. 2023;67:e0047523.
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  118. WANG X, Liu T, Lv X, Sun N, et al
    A Potential Nontraditional Approach To Combat tmexCD1-toprJ1-Mediated Tigecycline Resistance: Melatonin as a Synergistic Adjuvant of Tigecycline.
    Antimicrob Agents Chemother. 2023;67:e0004723.
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  119. VAN N, Degefu YN, Leus PA, Larkins-Ford J, et al
    Novel Synergies and Isolate Specificities in the Drug Interaction Landscape of Mycobacterium abscessus.
    Antimicrob Agents Chemother. 2023;67:e0009023.
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  120. ZHANG Y, Liu X, Wen H, Cheng Z, et al
    Anti-Biofilm Enzymes-Assisted Antibiotic Therapy against Burn Wound Infection by Pseudomonas aeruginosa.
    Antimicrob Agents Chemother. 2023;67:e0030723.
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  121. KANE Z, Cheng I, McGarrity O, Chiesa R, et al
    Model Based Estimation of Posaconazole Tablet and Suspension Bioavailability in Hospitalized Children Using Real-World Therapeutic Drug Monitoring Data in Patients Receiving Intravenous and Oral Dosing.
    Antimicrob Agents Chemother. 2023;67:e0007723.
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  122. MORELLI MK, Kloosterboer A, Fulton SA, Furin J, et al
    Investigating and Treating a Corneal Ulcer Due to Extensively Drug-Resistant Pseudomonas aeruginosa.
    Antimicrob Agents Chemother. 2023;67:e0027723.
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  123. SCOTT NE, Edwin Erayil S, Kline SE, Selmecki A, et al
    Rapid Evolution of Multidrug Resistance in a Candida lusitaniae Infection during Micafungin Monotherapy.
    Antimicrob Agents Chemother. 2023 Jul 10:e0054323. doi: 10.1128/aac.00543.
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  124. ZHU G, Chen S, Zhang Y, Lu L, et al
    Mitochondrial Membrane-Associated Protein Mba1 Confers Antifungal Resistance by Affecting the Production of Reactive Oxygen Species in Aspergillus fumigatus.
    Antimicrob Agents Chemother. 2023 Jul 10:e0022523. doi: 10.1128/aac.00225.
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  125. GINGRAS H, Peillard-Fiorente F, Godin C, Patron K, et al
    New Resistance Mutations Linked to Decreased Susceptibility to Solithromycin in Streptococcus pneumoniae Revealed by Chemogenomic Screens.
    Antimicrob Agents Chemother. 2023 Jul 6:e0039523. doi: 10.1128/aac.00395.
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    June 2023
  126. METZNER K, O'Meara MJ, Halligan B, Wotring JW, et al
    Imaging-Based Screening Identifies Modulators of the eIF3 Translation Initiation Factor Complex in Candida albicans.
    Antimicrob Agents Chemother. 2023 Jun 29:e0050323. doi: 10.1128/aac.00503.
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  127. HELFER VE, Dias BB, Lock GA, Tomaszewski CA, et al
    Population Pharmacokinetic Modeling of Free Plasma and Free Brain Concentrations of Ceftaroline in Healthy and Methicillin-Resistant Staphylococcus aureus-Infected Wistar Rats.
    Antimicrob Agents Chemother. 2023 Jun 27:e0038223. doi: 10.1128/aac.00382.
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  128. ALI AM, Radtke KK, Hesseling AC, Winckler J, et al
    QT Interval Prolongation with One or More QT-Prolonging Agents Used as Part of a Multidrug Regimen for Rifampicin-Resistant Tuberculosis Treatment: Findings from Two Pediatric Studies.
    Antimicrob Agents Chemother. 2023 Jun 26:e0144822. doi: 10.1128/aac.01448.
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  129. GRIES R, Dal Molin M, Chhen J, van Gumpel E, et al
    Characterization of Two Novel Inhibitors of the Mycobacterium tuberculosis Cytochrome bc(1) Complex.
    Antimicrob Agents Chemother. 2023 Jun 26:e0025123. doi: 10.1128/aac.00251.
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  130. SATLIN MJ, Simner PJ, Slover CM, Yamano Y, et al
    Cefiderocol Treatment for Patients with Multidrug- and Carbapenem-Resistant Pseudomonas aeruginosa Infections in the Compassionate Use Program.
    Antimicrob Agents Chemother. 2023 Jun 22:e0019423. doi: 10.1128/aac.00194.
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  131. HESS KA, Kooda K, Shirley JD, Schuetz AN, et al
    Failure of mecA/mecC PCR Testing to Accurately Predict Oxacillin Resistance in a Patient with Staphylococcus aureus Infective Endocarditis.
    Antimicrob Agents Chemother. 2023 Jun 21:e0043723. doi: 10.1128/aac.00437.
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  132. VAN DER LAAN LE, Garcia-Prats AJ, Schaaf HS, Chirehwa M, et al
    Erratum for van der Laan et al., "Pharmacokinetics and Dose Optimization Strategies of Para-Aminosalicylic Acid in Children with Rifampicin-Resistant Tuberculosis".
    Antimicrob Agents Chemother. 2023 Jun 20:e0072023. doi: 10.1128/aac.00720.
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  133. LIU Y, Ma L, Cheng J, Su J, et al
    Effects of Omeprazole on Recurrent Clostridioides difficile Infection Caused by ST81 Strains and Their Potential Mechanisms.
    Antimicrob Agents Chemother. 2023;67:e0022123.
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  134. KIM HH, Kim S, Kim MA, Jung CH, et al
    Stratification of Nontuberculous Mycobacterial Disease Risk in Type 2 Diabetes Based on Metformin Use: a Population-Based Cohort Study in South Korea.
    Antimicrob Agents Chemother. 2023;67:e0167522.
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  135. NGUYEN TQ, Heo BE, Hanh BTB, Jeon S, et al
    DS86760016, a Leucyl-tRNA Synthetase Inhibitor, Is Active against Mycobacterium abscessus.
    Antimicrob Agents Chemother. 2023;67:e0156722.
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  136. WANG L, Zhang X, Zhou X, Bi Y, et al
    Insertion of ISPa1635 in ISCR1 Creates a Hybrid Promoter for bla(PER-1) Resulting in Resistance to Novel beta-lactam/beta-lactamase Inhibitor Combinations and Cefiderocol.
    Antimicrob Agents Chemother. 2023;67:e0013523.
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  137. QIN Y, Wang J, Lv Q, Han B, et al
    Recent Progress in Research on Mitochondrion-Targeted Antifungal Drugs: a Review.
    Antimicrob Agents Chemother. 2023;67:e0000323.
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  138. BIDAUD AL, Moreno-Sabater A, Normand AC, Cremer G, et al
    Evaluation of Gradient Concentration Strips for Detection of Terbinafine Resistance in Trichophyton spp.
    Antimicrob Agents Chemother. 2023;67:e0171622.
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  139. ZHOU Y, Meng X, Chen F, Xiong M, et al
    Newly Discovered Antimicrobial Peptide Scyampcin(44-63) from Scylla paramamosain Exhibits a Multitargeted Candidacidal Mechanism In Vitro and Is Effective in a Murine Model of Vaginal Candidiasis.
    Antimicrob Agents Chemother. 2023;67:e0002223.
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  140. FUJIWARA K, Aono A, Asami T, Morimoto K, et al
    In Vitro Synergistic Effects of Omadacycline with Other Antimicrobial Agents against Mycobacterium abscessus.
    Antimicrob Agents Chemother. 2023;67:e0157922.
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  141. HURST-HESS K, Walz A, Yang Y, McGuirk H, et al
    Intrapulmonary Treatment with Mycobacteriophage LysB Rapidly Reduces Mycobacterium abscessus Burden.
    Antimicrob Agents Chemother. 2023;67:e0016223.
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  142. CHANG YS, Li SY, Pertinez H, Betoudji F, et al
    Using Dynamic Oral Dosing of Rifapentine and Rifabutin to Simulate Exposure Profiles of Long-Acting Formulations in a Mouse Model of Tuberculosis Preventive Therapy.
    Antimicrob Agents Chemother. 2023 Jun 14:e0048123. doi: 10.1128/aac.00481.
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  143. TSUI CK, Ben Abid F, Al Ismail K, McElheny CL, et al
    Genomic Epidemiology of Carbapenem-Resistant Klebsiella in Qatar: Emergence and Dissemination of Hypervirulent Klebsiella pneumoniae Sequence Type 383 Strains.
    Antimicrob Agents Chemother. 2023 Jun 13:e0003023. doi: 10.1128/aac.00030.
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    May 2023
  144. XU J, Li D, Shi J, Wang B, et al
    Bedquiline Resistance Mutations: Correlations with Drug Exposures and Impact on the Proteome in M. tuberculosis.
    Antimicrob Agents Chemother. 2023 May 31:e0153222. doi: 10.1128/aac.01532.
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  145. NELSON-RIGG R, Fagan SP, Jaremko WJ, Pata JD, et al
    Pre-Steady-State Kinetic Characterization of an Antibiotic-Resistant Mutant of Staphylococcus aureus DNA Polymerase PolC.
    Antimicrob Agents Chemother. 2023 May 24:e0157122. doi: 10.1128/aac.01571.
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  146. MORRISETTE T, Stamper KC, Lev KL, Kebriaei R, et al
    Evaluation of Omadacycline Alone and in Combination with Rifampin against Staphylococcus aureus and Staphylococcus epidermidis in an In Vitro Pharmacokinetic/Pharmacodynamic Biofilm Model.
    Antimicrob Agents Chemother. 2023 May 24:e0131722. doi: 10.1128/aac.01317.
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  147. KORDALEWSKA M, Cancino-Prado G, Nobrega de Almeida Junior J, Brasil Brandao I, et al
    Novel Non-Hot Spot Modification in Fks1 of Candida auris Confers Echinocandin Resistance.
    Antimicrob Agents Chemother. 2023 May 24:e0042323. doi: 10.1128/aac.00423.
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  148. DAWSON R, Diacon AH, Narunsky K, De Jager VR, et al
    Phase I Single Ascending Dose and Food Effect Study in Healthy Adults and Phase I/IIa Multiple Ascending Dose Study in Patients with Pulmonary Tuberculosis to Assess Pharmacokinetics, Bactericidal Activity, Tolerability, and Safety of OPC-167832.
    Antimicrob Agents Chemother. 2023 May 23:e0147722. doi: 10.1128/aac.01477.
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  149. JAKIELASZEK C, Hilliard JJ, Mannino F, Hossain M, et al
    Efficacy of Intravenously Administered Gepotidacin in Cynomolgus Macaques following a Francisella tularensis Inhalational Challenge.
    Antimicrob Agents Chemother. 2023;67:e0138122.
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  150. MASON CS, Avis T, Hu C, Nagalingam N, et al
    The Novel DNA Binding Mechanism of Ridinilazole, a Precision Clostridiodes difficile Antibiotic.
    Antimicrob Agents Chemother. 2023;67:e0156322.
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  151. HU X, Dong R, Huang S, Zeng Y, et al
    CDBN-YGXZ, a Novel Small-Molecule Drug, Shows Efficacy against Clostridioides difficile Infection and Recurrence in Mouse and Hamster Infection Models.
    Antimicrob Agents Chemother. 2023;67:e0170422.
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  152. KOCER K, Boudour-Halil D, Chanthalangsy Q, Sahr A, et al
    Genomic Modification of TonB and Emergence of Small-Colony Phenotype in VIM- and NDM-Producing Escherichia coli following Cefiderocol Exposure In Vitro.
    Antimicrob Agents Chemother. 2023;67:e0011823.
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  153. YETMAR ZA, Chesdachai S, Lahr BD, Challener DW, et al
    Comparison of Oral and Intravenous Definitive Antibiotic Therapy for Beta-Hemolytic Streptococcus Species Bloodstream Infections from Soft Tissue Sources: a Propensity Score-Matched Analysis.
    Antimicrob Agents Chemother. 2023 May 16:e0012023. doi: 10.1128/aac.00120.
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  154. XU L, Henriksen C, Mebus V, Guerillot R, et al
    A Clinically Selected Staphylococcus aureus clpP Mutant Survives Daptomycin Treatment by Reducing Binding of the Antibiotic and Adapting a Rod-Shaped Morphology.
    Antimicrob Agents Chemother. 2023 May 15:e0032823. doi: 10.1128/aac.00328.
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  155. JOHN LLH, Thomson DD, Bicanic T, Hoenigl M, et al
    Heightened Efficacy of Anidulafungin When Used in Combination with Manogepix or 5-Flucytosine against Candida auris In Vitro.
    Antimicrob Agents Chemother. 2023 May 10:e0164522. doi: 10.1128/aac.01645.
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  156. SINGH NV, Singh KV, Dinh AQ, Arias CA, et al
    Colocalization of Linezolid Resistance (cfr) and Virulence Factors Cytolysin and Hemolysin (cln and hln) on a Plasmid in Enterococcus faecalis.
    Antimicrob Agents Chemother. 2023 May 10:e0025923. doi: 10.1128/aac.00259.
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  157. MATHIYAZAKAN V, Wong CF, Harikishore A, Pethe K, et al
    Cryo-Electron Microscopy Structure of the Mycobacterium tuberculosis Cytochrome bcc:aa(3) Supercomplex and a Novel Inhibitor Targeting Subunit Cytochrome cI.
    Antimicrob Agents Chemother. 2023 May 9:e0153122. doi: 10.1128/aac.01531.
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  158. DAFFINEE KE, Piehl EC, Bleick C, LaPlante KL, et al
    Eradication of Staphylococcus epidermidis within Biofilms: Comparison of Systemic versus Supratherapeutic Concentrations of Antibiotics.
    Antimicrob Agents Chemother. 2023 May 8:e0010823. doi: 10.1128/aac.00108.
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  159. LEE JR, Satlin MJ
    Case Commentary: Unlocking the Potential of Bacteriophage to Prevent Recurrent Urinary Tract Infections after Kidney Transplantation.
    Antimicrob Agents Chemother. 2023 May 8:e0044923. doi: 10.1128/aac.00449.
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    April 2023
  160. STONE MC, Mychack A, Coe KA, Walker S, et al
    Combining Signal Peptidase and Lipoprotein Processing Inhibitors Overcomes Ayr Resistance in Staphylococcus aureus.
    Antimicrob Agents Chemother. 2023 Apr 25:e0011523. doi: 10.1128/aac.00115.
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  161. ZHU Y, Zhu L, Davies Forsman L, Paues J, et al
    Population Pharmacokinetics and Dose Evaluation of Cycloserine among Patients with Multidrug-Resistant Tuberculosis under Standardized Treatment Regimens.
    Antimicrob Agents Chemother. 2023 Apr 25:e0170022. doi: 10.1128/aac.01700.
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  162. BEATTIE SR, Esan T, Zarnowski R, Eix E, et al
    Novel Keto-Alkyl-Pyridinium Antifungal Molecules Active in Models of In Vivo Candida albicans Vascular Catheter Infection and Ex Vivo Candida auris Skin Colonization.
    Antimicrob Agents Chemother. 2023 Apr 25:e0008123. doi: 10.1128/aac.00081.
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  163. SOBEL JD
    Resistance to Fluconazole of Candida albicans in Vaginal Isolates: a 10-Year Study in a Clinical Referral Center.
    Antimicrob Agents Chemother. 2023 Apr 24:e0018123. doi: 10.1128/aac.00181.
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  164. ELGAMMAL Y, Salama EA, Seleem MN
    Atazanavir Resensitizes Candida auris to Azoles.
    Antimicrob Agents Chemother. 2023 Apr 24:e0163122. doi: 10.1128/aac.01631.
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  165. WOOD GE, Kim CM, Aguila LKT, Cichewicz RH, et al
    In Vitro Susceptibility and Resistance of Mycoplasma genitalium to Nitroimidazoles.
    Antimicrob Agents Chemother. 2023;67:e0000623.
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  166. RODRIGUEZ R, Campbell-Kruger N, Gonzalez Camba J, Berude J, et al
    MarR-Dependent Transcriptional Regulation of mmpSL5 Induces Ethionamide Resistance in Mycobacterium abscessus.
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  167. HODGES MR, Ople E, Wedel P, Shaw KJ, et al
    Safety and Pharmacokinetics of Intravenous and Oral Fosmanogepix, a First-in-Class Antifungal Agent, in Healthy Volunteers.
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  168. WANG C, Sun Z, Hu Y, Li D, et al
    A Novel Anti-CRISPR AcrIE9.2 Is Associated with Dissemination of bla(KPC) Plasmids in Klebsiella pneumoniae Sequence Type 15.
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  169. HUANG Y, Wu Y, Cai C, Zhang R, et al
    Phenotypic and Genomic Characterization of ST133 Siderophore-Encoding Extensively Drug-Resistant Enterobacter hormaechei.
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  170. NEGATU DA, Aragaw WW, Cangialosi J, Dartois V, et al
    Side-by-Side Profiling of Oxazolidinones to Estimate the Therapeutic Window against Mycobacterial Infections.
    Antimicrob Agents Chemother. 2023;67:e0165522.
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  171. D'ANGELO F, Rocha EPC, Rendueles O
    The Capsule Increases Susceptibility to Last-Resort Polymyxins, but Not to Other Antibiotics, in Klebsiella pneumoniae.
    Antimicrob Agents Chemother. 2023;67:e0012723.
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  172. LIU Y, Moodley M, Pasipanodya JG, Gumbo T, et al
    Determining the Delamanid Pharmacokinetics/Pharmacodynamics Susceptibility Breakpoint Using Monte Carlo Experiments.
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  173. ARMENGOL E, Kragh KN, Tolker-Nielsen T, Sierra JM, et al
    Colistin Enhances Rifampicin's Antimicrobial Action in Colistin-Resistant Pseudomonas aeruginosa Biofilms.
    Antimicrob Agents Chemother. 2023;67:e0164122.
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  174. TANG B, Yang A, Liu P, Wang Z, et al
    Outer Membrane Vesicles Transmitting bla(NDM-1) Mediate the Emergence of Carbapenem-Resistant Hypervirulent Klebsiella pneumoniae.
    Antimicrob Agents Chemother. 2023 Apr 13:e0144422. doi: 10.1128/aac.01444.
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  175. VAZQUEZ JA, Pappas PG, Boffard K, Paruk F, et al
    Clinical Efficacy and Safety of a Novel Antifungal, Fosmanogepix, in Patients with Candidemia Caused by Candida auris: Results from a Phase 2 Trial.
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    March 2023
  176. KHATEB A, Gago S, Bromley M, Richardson M, et al
    Aneuploidy Is Associated with Azole Resistance in Aspergillus fumigatus.
    Antimicrob Agents Chemother. 2023 Mar 28:e0125322. doi: 10.1128/aac.01253.
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    Pharmacokinetics and Efficacy of the Benzothiazinone BTZ-043 against Tuberculous Mycobacteria inside Granulomas in the Guinea Pig Model.
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  178. HASHIMOTO Y, Suzuki M, Kobayashi S, Hirahara Y, et al
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  179. LI D, Ge Y, Wang N, Shi Y, et al
    Identification and Characterization of a Novel Major Facilitator Superfamily Efflux Pump, SA09310, Mediating Tetracycline Resistance in Staphylococcus aureus.
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  180. BHAVNANI SM, Hammel JP, Lakota EA, Trang M, et al
    Pharmacokinetic-Pharmacodynamic Target Attainment Analyses Evaluating Omadacycline Dosing Regimens for the Treatment of Patients with Community-Acquired Bacterial Pneumonia Arising from Streptococcus pneumoniae and Haemophilus influenzae.
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  181. SLARVE M, Reyna Z, Burk E, Ruiz-Delgado J, et al
    Therapeutic, Humanized Monoclonal Antibody Exhibits Broad Binding and Protective Efficacy against Acinetobacter baumannii.
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  182. HALLAL FERREIRA RARO O, Nordmann P, Dominguez Pino M, Findlay J, et al
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  183. DE JESUS DFF, De Freitas ALD, De Oliveira IM, De Almeida LC, et al
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  184. ZHANG P, Hu H, Shi Q, Sun L, et al
    The Effect of beta-Lactam Antibiotics on the Evolution of Ceftazidime/Avibactam and Cefiderocol Resistance in KPC-Producing Klebsiella pneumoniae.
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  185. HIRAYAMA T, Miyazaki T, Sumiyoshi M, Ito Y, et al
    Echinocandin Resistance in Candida auris Occurs in the Murine Gastrointestinal Tract Due to FKS1 Mutations.
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  186. LI SY, Converse PJ, Betoudji F, Lee J, et al
    Next-Generation Diarylquinolines Improve Sterilizing Activity of Regimens with Pretomanid and the Novel Oxazolidinone TBI-223 in a Mouse Tuberculosis Model.
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  187. ISMAIL N, Dippenaar A, Warren RM, Peters RPH, et al
    Emergence of Canonical and Noncanonical Genomic Variants following In Vitro Exposure of Clinical Mycobacterium tuberculosis Strains to Bedaquiline or Clofazimine.
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  188. IMBERT S, Normand AC, Costa D, Gabriel F, et al
    Multicentric Analysis of the Species Distribution and Antifungal Susceptibility of Clinical Isolates from Aspergillus Section Circumdati.
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  189. CABELLOS C, Guillem L, Pelegrin I, Tubau F, et al
    Reply to Le Turnier et al., "Empirical Treatment in Acute Bacterial Meningitis: a Plea for High Doses of Cefotaxime or Ceftriaxone".
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  190. LE TURNIER P, Tattevin P, Varon E, Duval X, et al
    Empirical Treatment in Acute Bacterial Meningitis: a Plea for High Doses of Cefotaxime or Ceftriaxone.
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  191. MISHRA NN, Abdelhady W, Elsayed AM, Lapitan C, et al
    Combinations of Daptomycin plus Ceftriaxone, but Not Ascending Daptomycin Dose-Regimens, Are Effective in Experimental Endocarditis Caused by Streptococcus mitis-oralis Strains: Target Tissue Clearances and Prevention of Emergence of Daptomycin-Resist
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  192. ARENDS SJR, Butler D, Scangarella-Oman N, Castanheira M, et al
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    February 2023
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    Hospital Clonal Outbreak of Fluconazole-Resistant Candida parapsilosis Harboring the Y132F ERG11p Substitution in a French Intensive Care Unit.
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  194. LOHSEN S, Stephens DS
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  195. ABDELGAWAD N, Tshavhungwe MP, Rohlwink U, McIlleron H, et al
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  196. TASCINI C, Antonelli A, Pini M, De Vivo S, et al
    Infective Endocarditis Associated with Implantable Cardiac Device by Metallo-beta-Lactamase-Producing Pseudomonas aeruginosa, Successfully Treated with Source Control and Cefiderocol Plus Imipenem.
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  197. LEDGER EVK, Lau K, Tate EW, Edwards AM, et al
    XerC Is Required for the Repair of Antibiotic- and Immune-Mediated DNA Damage in Staphylococcus aureus.
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  198. CABOT G, Kim K, Mark BL, Oliver A, et al
    Biochemical Insights into Imipenem Collateral Susceptibility Driven by ampC Mutations Conferring Ceftolozane/Tazobactam Resistance in Pseudomonas aeruginosa.
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  199. NEGATU DA, Gonzalez Del Rio R, Cacho-Izquierdo M, Barros-Aguirre D, et al
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  200. GARCIA A, Huh EY, Lee SC
    Serine/Threonine Phosphatase Calcineurin Orchestrates the Intrinsic Resistance to Micafungin in the Human-Pathogenic Fungus Mucor circinelloides.
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  201. KUNKEL M, Doyle-Eisele M, Kuehl P, Rotermund K, et al
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  202. LONG J, Zhang J, Xi Y, Zhao J, et al
    Genomic Insights into CRISPR-Harboring Plasmids in the Klebsiella Genus: Distribution, Backbone Structures, Antibiotic Resistance, and Virulence Determinant Profiles.
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  203. ALMEIDA DV, Converse PJ, Nuermberger EL
    Mutations in Rv0678 Reduce Susceptibility of Mycobacterium tuberculosis to the DprE1 Inhibitor TBA-7371.
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  204. BONN CM, Rafiqullah IM, Crawford JA, Qian YM, et al
    Repeated Emergence of Variant TetR Family Regulator, FarR, and Increased Resistance to Antimicrobial Unsaturated Fatty Acid among Clonal Complex 5 Methicillin-Resistant Staphylococcus aureus.
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  205. CHIREHWA MT, Resendiz-Galvan JE, Court R, De Kock M, et al
    Optimizing Moxifloxacin Dose in MDR-TB Participants with or without Efavirenz Coadministration Using Population Pharmacokinetic Modeling.
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    January 2023
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    Penicillin-Binding Proteins and Alternative Dual-Beta-Lactam Combinations for Serious Enterococcus faecalis Infections with Elevated Penicillin MICs.
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  207. JIMENEZ-TORO I, Rodriguez CA, Zuluaga AF, Otalvaro JD, et al
    Pharmacokinetic/Pharmacodynamic Index Linked to In Vivo Efficacy of the Ampicillin-Ceftriaxone Combination against Enterococcus faecalis.
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  208. SHEWELL LK, Day CJ, De Bisscop X, Edwards JL, et al
    Repurposing Carbamazepine To Treat Gonococcal Infection in Women: Oral Delivery for Control of Epilepsy Generates Therapeutically Effective Levels in Vaginal Secretions.
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  209. TRANG M, Hammel JP, Lakota EA, Safir MC, et al
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  210. ZEISER ET, Becka SA, LiPuma JJ, Papp-Wallace KM, et al
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  211. SHINOHARA K, Fujisawa T, Chang B, Ito Y, et al
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  212. LIU H, Zhu H, Fu L, Zhang W, et al
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  213. REICHLEN MJ, Born SEM, Lyons MA, Rossmassler K, et al
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  214. JARRETT RT, van der Heijden Y, Shotwell MS, Chihota V, et al
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  215. BLANCO-DI MATTEO A, Garcia-Fernandez N, Aguinaga Perez A, Carmona-Torre F, et al
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  216. BROWN KL, Wilburn KM, Montague CR, Grigg JC, et al
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  217. ZHANG F, Li Z, Liu X, Luo G, et al
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  218. MCNEIL JC, Sommer LM, Vallejo JG, Boyle M, et al
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    December 2022
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  220. AHMAD MN, Garg T, Singh S, Shukla R, et al
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  221. BOONSTRA JM, van der Elst KC, Zijlstra JG, van der Werf TS, et al
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  222. MANESH A, Devasagayam E, Bhanuprasad K, Mathew SK, et al
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  223. ZHANG J, Chen L, Gomez-Simmonds A, Yin MT, et al
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  224. PARK YE, Chong YP, Lee HJ, Shim TS, et al
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  225. BONNET PL, Le Gal S, Gautier C, Hoffmann CV, et al
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  226. GEHRKE AE, Mendoza-Bertelli A, Ledo C, Gonzalez CD, et al
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  227. KIM J, Choi J, Kang H, Ahn J, et al
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  228. RHODES NJ, Rohani R, Yarnold PR, Pawlowski AE, et al
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  229. MILLER S, Goy K, She R, Spellberg B, et al
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    November 2022
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  231. WONG CF, Saw WG, Basak S, Sano M, et al
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  232. YU XH, Hao ZH, Liu PL, Liu MM, et al
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  233. HULL RC, Wright RCT, Sayers JR, Sutton JAF, et al
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  234. MANSJO M, Karlsson Lindsjo O, Gronfors Seeth C, Groenheit R, et al
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  235. LYONS MA
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  236. NELSON M, Burton N, Nunez A, Butcher W, et al
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  238. WINTERS CG, Basnet RM, Faasuamalie PE, Shallom SJ, et al
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  239. SAH SK, Bhattacharya S, Yadav A, Husain F, et al
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  240. YEO HH, Shiau CW, Jao YH, Wan TW, et al
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  241. SARATHY JP, Zimmerman MD, Gengenbacher M, Dartois V, et al
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  243. MON AS, Ei PW, Htwe MM, Nyunt MH, et al
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  244. CABELLOS C, Guillem L, Pelegrin I, Tubau F, et al
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  245. NGUYEN TQ, Hanh BTB, Jeon S, Heo BE, et al
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    October 2022
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  247. SINGH KV, Montealegre MC, Murray BE
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  248. MCNEIL JC, Sommer LM, Vallejo JG, Hulten KG, et al
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  252. AL-ZUBAIDI A, Cheung CY, Cook GM, Taiaroa G, et al
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  254. PINCUS NB, Rosas-Lemus M, Gatesy SWM, Bertucci HK, et al
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  257. KIM TY, Huh HJ, Lee GY, Choi MJ, et al
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  260. YAO S, Wei D, Tang N, Song Y, et al
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  261. PI R, Chen X, Meng J, Liu Q, et al
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    Antimicrob Agents Chemother. 2022 Oct 3:e0068122. doi: 10.1128/aac.00681.
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    September 2022
  263. MENDES RE, Hubler C, Kimbrough JH, Kantro V, et al
    In Vitro Activity of Tebipenem against Various Resistant Subsets of Escherichia coli Causing Urinary Tract Infections in the United States (2018 to 2020).
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  264. YAMADA W, Kim S, Almoslem M, Kim S, et al
    Combination Therapy to Kill Mycobacterium tuberculosis in Its Nonreplicating Persister Phenotype.
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  265. COX GW, Avery BP, Parmley EJ, Irwin RJ, et al
    A One Health Genomic Investigation of Gentamicin Resistance in Escherichia coli from Human and Chicken Sources in Canada, 2014 to 2017.
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  266. CUSUMANO JA, Daffinee KE, Piehl EC, Garcia-Solache M, et al
    Meropenem plus Ceftaroline Is Active against Enterococcus faecalis in an In Vitro Pharmacodynamic Model Using Humanized Dosing Simulations.
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  267. RUEGSEGGER L, Xiao J, Naziripour A, Kanumuambidi T, et al
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  268. LIU F, Gao J, Gao M, Liu Y, et al
    Development and Validation of a Nomogram for Prediction of QT Interval Prolongation in Patients Administered Bedaquiline-Containing Regimens in China: a Modeling Study.
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  269. MADANI A, Negatu DA, El Marrouni A, Miller RR, et al
    Activity of Tricyclic Pyrrolopyrimidine Gyrase B Inhibitor against Mycobacterium abscessus.
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  270. KARLOWSKY JA, Hackel MA, McLeod SM, Miller AA, et al
    In Vitro Activity of Sulbactam-Durlobactam against Global Isolates of Acinetobacter baumannii-calcoaceticus Complex Collected from 2016 to 2021.
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  271. HOBSON CA, Pierrat G, Tenaillon O, Bonacorsi S, et al
    Klebsiella pneumoniae Carbapenemase Variants Resistant to Ceftazidime-Avibactam: an Evolutionary Overview.
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  272. JEN FE, Edwards JL, El-Deeb IM, Walker MJ, et al
    Repurposing the Ionophore, PBT2, for Treatment of Multidrug-Resistant Neisseria gonorrhoeae Infections.
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  273. PARK S, Russo R, Westfall L, Shrestha R, et al
    A Novel Oral GyrB/ParE Dual Binding Inhibitor Effective against Multidrug-Resistant Neisseria gonorrhoeae and Other High-Threat Pathogens.
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  274. LEWIS JS 2ND, Wiederhold NP, Hakki M, Thompson GR 3rd, et al
    New Perspectives on Antimicrobial Agents: Isavuconazole.
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  275. WU W, He S, Li A, Guo Q, et al
    A Novel Leucyl-tRNA Synthetase Inhibitor, MRX-6038, Expresses Anti-Mycobacterium abscessus Activity In Vitro and In Vivo.
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  276. CHAE G, Park YE, Chong YP, Lee HJ, et al
    Treatment Outcomes of Cavitary Nodular Bronchiectatic-Type Mycobacterium avium Complex Pulmonary Disease.
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  277. BROWN-ELLIOTT BA, Wallace RJ Jr
    In Vitro Susceptibility Testing of Eravacycline against Nontuberculous Mycobacteria.
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  278. LUTERBACH CL, Qiu H, Hanafin PO, Sharma R, et al
    A Systems-Based Analysis of Mono- and Combination Therapy for Carbapenem-Resistant Klebsiella pneumoniae Bloodstream Infections.
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  279. ZOU J, Chen S, Rao W, Fu L, et al
    Population Pharmacokinetic Modeling of Bedaquiline among Multidrug-Resistant Pulmonary Tuberculosis Patients from China.
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  280. SUNDELL J, Bienvenu E, Birgersson S, Abelo A, et al
    Effects of Enzyme Induction and Polymorphism on the Pharmacokinetics of Isoniazid and Rifampin in Tuberculosis/HIV Patients.
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  281. STANTON RA, Campbell D, McAllister GA, Breaker E, et al
    Whole-Genome Sequencing Reveals Diversity of Carbapenem-Resistant Pseudomonas aeruginosa Collected through CDC's Emerging Infections Program, United States, 2016-2018.
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    August 2022
  282. KIM LH, Kang SM, Whang J, Kwon KW, et al
    Novel Antibacterial Activity of Febuxostat, an FDA-Approved Antigout Drug against Mycobacterium tuberculosis Infection.
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  283. SHEE S, Singh S, Tripathi A, Thakur C, et al
    Moxifloxacin-Mediated Killing of Mycobacterium tuberculosis Involves Respiratory Downshift, Reductive Stress, and Accumulation of Reactive Oxygen Species.
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  284. SARIS A, Qin W, van Linge CCA, Reijnders TDY, et al
    The Azithromycin Pro-Drug CSY5669 Boosts Bacterial Killing While Attenuating Lung Inflammation Associated with Pneumonia Caused by Methicillin-Resistant Staphylococcus aureus.
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  285. POIREL L, Ortiz de la Rosa JM, Sakaoglu Z, Kusaksizoglu A, et al
    NDM-35-Producing ST167 Escherichia coli Highly Resistant to beta-Lactams Including Cefiderocol.
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  286. MENON ND, Penziner S, Montano ET, Zurich R, et al
    Increased Innate Immune Susceptibility in Hyperpigmented Bacteriophage-Resistant Mutants of Pseudomonas aeruginosa.
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  287. MCPHERSON J, Hu C, Begum K, Wang W, et al
    Functional and Metagenomic Evaluation of Ibezapolstat for Early Evaluation of Anti-Recurrence Effects in Clostridioides difficile Infection.
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  288. OSTAPSKA H, Raju D, Corsini R, Lehoux M, et al
    Preclinical Evaluation of Recombinant Microbial Glycoside Hydrolases as Antibiofilm Agents in Acute Pulmonary Pseudomonas aeruginosa Infection.
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  289. COSTA DVS, Pham NVS, Hays RA, Bolick DT, et al
    Influence of Binary Toxin Gene Detection and Decreased Susceptibility to Antibiotics among Clostridioides difficile Strains on Disease Severity: a Single-Center Study.
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  290. WIEDERHOLD NP, Patterson TF, Rebholz S, Boal CWC, et al
    The Antifungal and Anti-Pneumocystis Activities of the Novel Compound A3IS (Mycosinate).
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  291. CHOCHUA S, Metcalf B, Li Z, Mathis S, et al
    Invasive Group A Streptococcal Penicillin Binding Protein 2x Variants Associated with Reduced Susceptibility to beta-Lactam Antibiotics in the United States, 2015-2021.
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  292. GEBERETSADIK G, Inaizumi A, Nishiyama A, Yamaguchi T, et al
    Lysocin E Targeting Menaquinone in the Membrane of Mycobacterium tuberculosis Is a Promising Lead Compound for Antituberculosis Drugs.
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  293. VALCEK A, Nesporova K, Whiteway C, De Pooter T, et al
    Genomic Analysis of a Strain Collection Containing Multidrug-, Extensively Drug-, Pandrug-, and Carbapenem-Resistant Modern Clinical Isolates of Acinetobacter baumannii.
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  294. BRUNAUGH AD, Walz A, Warnken Z, Pearce C, et al
    Respirable Clofazimine Particles Produced by Air Jet Milling Technique Are Efficacious in Treatment of BALB/c Mice with Chronic Mycobacterium tuberculosis Infection.
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  295. BARNIER JP, Saidjalolov S, Bouchet F, Mayer L, et al
    Modulation of the Specificity of Carbapenems and Diazabicyclooctanes for Selective Activity against Mycobacterium tuberculosis.
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  296. YUN HY, Chang MJ, Jung H, Chang V, et al
    Prothionamide Dose Optimization Using Population Pharmacokinetics for Multidrug-Resistant Tuberculosis Patients.
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  297. DING Y, Zhu H, Fu L, Zhang W, et al
    Superior Efficacy of a TBI-166, Bedaquiline, and Pyrazinamide Combination Regimen in a Murine Model of Tuberculosis.
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  298. ESCRIBANO P, Gomez A, Reigadas E, Munoz P, et al
    EUCAST-Obtained Olorofim MICs against Aspergillus and Scedosporium Species and Lomentospora prolificans Showed High Agreements between Visual Inspection and Spectrophotometric Readings.
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  299. POULTON NC, Azadian ZA, DeJesus MA, Rock JM, et al
    Mutations in rv0678 Confer Low-Level Resistance to Benzothiazinone DprE1 Inhibitors in Mycobacterium tuberculosis.
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  300. COLABARDINI AC, Van Rhijn N, LaBella AL, Valero C, et al
    Aspergillus fumigatus FhdA Transcription Factor Is Important for Mitochondrial Activity and Codon Usage Regulation during the Caspofungin Paradoxical Effect.
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  301. EDLIND T, Katiyar S
    Intrinsically High Resistance of Candida glabrata to Hydrogen Peroxide and Its Reversal in a Fluconazole-Resistant Mutant.
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  302. GRACIAA DS, Kipiani M, Magee MJ, Mikiashvili L, et al
    Linezolid Exposure Is Associated with Cytopenias in Patients Treated for Multidrug-Resistant Tuberculosis.
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    July 2022
  303. SHELTON CD, McNeil MB, Early JV, Ioerger TR, et al
    Correction for Shelton et al., "Deletion of Rv2571c Confers Resistance to Arylamide Compounds in Mycobacterium tuberculosis".
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  304. CHANG SC, Lin LC, Lu JJ
    An lnu(A)-Carrying Multi-Resistance Plasmid Derived from Sequence Type 3 Methicillin-Resistant Staphylococcus lugdunensis May Contribute to Antimicrobial Resistance in Staphylococci.
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  305. HARISH E, Sarkar A, Handelman M, Abo Kandil A, et al
    Triazole Priming as an Adaptive Response and Gateway to Resistance in Aspergillus fumigatus.
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  306. LOPEZ-CERERO L, Stolz E, Pulido MR, Pascual A, et al
    Characterization of Extended-Spectrum beta-Lactamase-Producing Shigella sonnei in Spain: Expanding the Geographic Distribution of Sequence Type 152/CTX-M-27 Clone.
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  307. DAI YY, Qin C, Huang GR, Qin YC, et al
    Linolenic Acid-Metronidazole: a Compound Relieving Drug Resistance and Inhibiting Helicobacter pylori.
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  308. MADDEN GR, Petri WA Jr, Costa DVS, Warren CA, et al
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  309. O'DONNELL JN, Lodise TP
    New Perspectives on Antimicrobial Agents: Imipenem-Relebactam.
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  310. SEN T, Verma NK
    Functional Role of YnfA, an Efflux Transporter in Resistance to Antimicrobial Agents in Shigella flexneri.
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  311. PARK JJ, Jung EJ, Kim JY, Seo YB, et al
    Thirty-Day Mortality Rates in Patients with Extended-Spectrum beta-Lactamase-Producing Enterobacterales Bacteremia Receiving Ertapenem versus Other Carbapenems.
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  312. DESAI JV, Urban A, Swaim DZ, Colton B, et al
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  313. GEBREMARIAM T, Gu Y, Alkhazraji S, Youssef E, et al
    The Combination Treatment of Fosmanogepix and Liposomal Amphotericin B Is Superior to Monotherapy in Treating Experimental Invasive Mold Infections.
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  314. PITOUT JDD, Peirano G, Chen L, DeVinney R, et al
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  315. MTSHALI S, Jacobs BA
    A Comparative Analysis of Physiologically Based Pharmacokinetic Models for Human Immunodeficiency Virus and Tuberculosis Infections.
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  316. DIAZ-GARCIA J, Gomez A, Alcala L, Reigadas E, et al
    Evidence of Fluconazole-Resistant Candida parapsilosis Genotypes Spreading across Hospitals Located in Madrid, Spain and Harboring the Y132F ERG11p Substitution.
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  317. MEHTA K, Guo T, Wallis RS, van der Graaf PH, et al
    Quantitative Systems Pharmacology Modeling Framework of Autophagy in Tuberculosis: Application to Adjunctive Metformin Host-Directed Therapy.
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  318. KONG X, Wang B, Chen X, Wang L, et al
    Hinokiflavone Attenuates the Virulence of Methicillin-Resistant Staphylococcus aureus by Targeting Caseinolytic Protease P.
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  319. KNOLL MA, Samardzic E, Posch W, Lass-Florl C, et al
    Evaluation of Inoculum Preparation for Etest and EUCAST Broth Dilution to Detect Anidulafungin Polyresistance in Candida glabrata.
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  320. SOUCHE A, Kolenda C, Teoli J, Schuch R, et al
    Activity of Exebacase (CF-301) against Biofilms Formed by Staphylococcus epidermidis Strains Isolated from Prosthetic Joint Infections.
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  321. WATANABE F, Furuuchi K, Hanada K, Fujiwara K, et al
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    June 2022
  322. JACOBS SE, Jacobs JL, Dennis EK, Taimur S, et al
    Candida auris Pan-Drug-Resistant to Four Classes of Antifungal Agents.
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  323. HSU AJ, Tamma PD, Fisher BT
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  324. BAE S, Kim ES, Kim HS, Yang E, et al
    Risk Factors of Recurrent Infection in Patients with Staphylococcus aureus Bacteremia: a Competing Risk Analysis.
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  325. RIVIERE E, Verboven L, Dippenaar A, Goossens S, et al
    Variants in Bedaquiline-Candidate-Resistance Genes: Prevalence in Bedaquiline-Naive Patients, Effect on MIC, and Association with Mycobacterium tuberculosis Lineage.
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  326. KWIECINSKI JM, Jelani DA, Fuentes EJ, Horswill AR, et al
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  327. ABOLHASSANI-CHIMEH R, Akkerman OW, Saktiawati AMI, Punt NC, et al
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  328. PHILLIPS EC, Warren CA, Ma JZ, Madden GR, et al
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  329. RIMAL B, Batchelder HR, Story-Roller E, Panthi CM, et al
    T405, a New Penem, Exhibits In Vivo Efficacy against M. abscessus and Synergy with beta-Lactams Imipenem and Cefditoren.
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  330. XIE J, Yang Q, Han X, Dong Y, et al
    Pharmacokinetic/Pharmacodynamic Target Attainment of Different Antifungal Agents in De-escalation Treatment in Critically Ill Patients: a Step toward Dose Optimization Using Monte Carlo Simulation.
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  331. WILLIAMS E, Zhang B, Chow EPF, Chea S, et al
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  332. HUGGINS JP, Pease R, Stanly K, Workman A, et al
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  333. TRAN TT, Gomez Villegas S, Aitken SL, Butler-Wu SM, et al
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  334. WALTER K, Kokesch-Himmelreich J, Treu A, Waldow F, et al
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  335. TONG K, Wei J, Gu H, Hu Q, et al
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  336. MCCALLIN S, Menzi C, Lassen S, Daraspe J, et al
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  337. DOORLEY LA, Rybak JM, Berkow EL, Zhang Q, et al
    Candida parapsilosis Mdr1B and Cdr1B Are Drivers of Mrr1-Mediated Clinical Fluconazole Resistance.
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  338. SONG W, Wang L, Jin M, Guo X, et al
    Punicalagin, an Inhibitor of Sortase A, Is a Promising Therapeutic Drug to Combat Methicillin-Resistant Staphylococcus aureus Infections.
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  339. SHIVARATHRI R, Jenull S, Chauhan M, Singh A, et al
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  340. SHAO Y, Chen M, Luo J, Li D, et al
    Serogroup Y Clonal Complex 23 Meningococcus in China Acquiring Penicillin Resistance from Commensal Neisseria lactamica Species.
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  341. ZHOU Y, Zhong Z, Hu S, Wang J, et al
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  342. CHEN M, Zhong G, Wang S, Chen P, et al
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    May 2022
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  347. LI X, Le W, Lou X, Genco CA, et al
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  348. MURRAY GL, Bodiyabadu K, Vodstrcil LA, Machalek DA, et al
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  349. PRASAD NK, Seiple IB, Cirz RT, Rosenberg OS, et al
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  350. GAO W, Passarell J, Patel YT, Zhang Z, et al
    Exposure-Efficacy Analyses Support Optimal Dosing Regimens of Ceftolozane/Tazobactam in Participants with Hospital-Acquired/Ventilator-Associated Bacterial Pneumonia in ASPECT-NP.
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  351. PAUL A, Nair RR, Jakkala K, Pradhan A, et al
    Elevated Levels of Three Reactive Oxygen Species and Fe(II) in the Antibiotic-Surviving Population of Mycobacteria Facilitate De Novo Emergence of Genetic Resisters to Antibiotics.
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  352. HUJER AM, Bethel CR, Taracila MA, Marshall SH, et al
    Imipenem/Relebactam Resistance in Clinical Isolates of Extensively Drug Resistant Pseudomonas aeruginosa: Inhibitor-Resistant beta-Lactamases and Their Increasing Importance.
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  353. SCHULTHESS B, Akdogan Kittana FN, Homke R, Sander P, et al
    In Vitro Bedaquiline and Clofazimine Susceptibility Testing in Mycobacterium abscessus.
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  354. CHUA TP, Danielewski J, Bodiyabadu K, Bradshaw CS, et al
    Impact of 16S rRNA Single Nucleotide Polymorphisms on Mycoplasma genitalium Organism Load with Doxycycline Treatment.
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  355. LANDLINGER C, Oberbauer V, Podpera Tisakova L, Schwebs T, et al
    Preclinical Data on the Gardnerella-Specific Endolysin PM-477 Indicate Its Potential to Improve the Treatment of Bacterial Vaginosis through Enhanced Biofilm Removal and Avoidance of Resistance.
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  356. DESNOS-OLLIVIER M, Bretagne S, Lortholary O, Dromer F, et al
    Echinocandins Susceptibility Patterns of 2,787 Yeast Isolates: Importance of the Thresholds for the Detection of FKS Mutations.
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  357. KARABA SM, Hirsch EB, Heil EL
    In a Pinch: Cefiderocol for CRAB Infections.
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  358. KARABASEVIC N, Roberts JA, Stronach L, Naicker S, et al
    Use of the Hollow-Fiber Infection Model to Measure the Effect of Combination Therapy of Septic Shock Exposures of Meropenem and Ciprofloxacin against Intermediate and Resistant Pseudomonas aeruginosa Clinical Isolates.
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  359. ERSOY SC, Manna AC, Proctor RA, Chambers HF, et al
    The NaHCO3-Responsive Phenotype in Methicillin-Resistant Staphylococcus aureus (MRSA) Is Influenced by mecA Genotype.
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  360. SUPANDY A, Mehta HH, Tran TT, Miller WR, et al
    Evolution of Enterococcus faecium in Response to a Combination of Daptomycin and Fosfomycin Reveals Distinct and Diverse Adaptive Strategies.
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  361. FUCHS F, Aldejohann AM, Hoffmann AM, Walther G, et al
    In Vitro Activity of Nitroxoline in Antifungal-Resistant Candida Species Isolated from the Urinary Tract.
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  362. MOURAD A, Holland TL, Turner NA
    Antiplatelet Therapy in Staphylococcus aureus Bacteremia: No Time Like the Past?
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  363. CONKLE-GUTIERREZ D, Kim C, Ramirez-Busby SM, Modlin SJ, et al
    Distribution of Common and Rare Genetic Markers of Second-Line-Injectable-Drug Resistance in Mycobacterium tuberculosis Revealed by a Genome-Wide Association Study.
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  364. VAN DER LAAN LE, Garcia-Prats AJ, Schaaf HS, Chirehwa M, et al
    Pharmacokinetics and Dose Optimization Strategies of Para-Aminosalicylic Acid in Children with Rifampicin-Resistant Tuberculosis.
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    April 2022
  365. RAGUNATHAN P, Dick T, Gruber G
    Anti-Mycobacterium abscessus Activity of Tuberculosis F-ATP Synthase Inhibitor GaMF1.
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  366. MADDEN DE, Olagoke O, Baird T, Neill J, et al
    Express Yourself: Quantitative Real-Time PCR Assays for Rapid Chromosomal Antimicrobial Resistance Detection in Pseudomonas aeruginosa.
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  367. HOLLEY CL, Dhulipala V, Balthazar JT, Le Van A, et al
    A Single Amino Acid Substitution in Elongation Factor G Can Confer Low-Level Gentamicin Resistance in Neisseria gonorrhoeae.
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  368. SALAMA OE, Gerstein AC
    Differential Response of Candida Species Morphologies and Isolates to Fluconazole and Boric Acid.
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  369. ROUCHON CN, Harris J, Zubair-Nizami Z, Weinstein AJ, et al
    The Cationic Antimicrobial Peptide Activity of Lysozyme Reduces Viable Enterococcus faecalis Cells in Biofilms.
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  370. SRIVASTAVA S, Boorgula GD, Wang JY, Huang HL, et al
    Rifampin Pharmacokinetics/Pharmacodynamics in the Hollow-Fiber Model of Mycobacterium kansasii Infection.
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  371. POIREL L, Ortiz de la Rosa JM, Sadek M, Nordmann P, et al
    Impact of Acquired Broad-Spectrum beta-Lactamases on Susceptibility to Cefiderocol and Newly Developed beta-Lactam/beta-Lactamase Inhibitor Combinations in Escherichia coli and Pseudomonas aeruginosa.
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  372. RAJA SM, Guptill JT, Juel VC, Walter EB, et al
    First-in-Human Clinical Trial to Assess the Safety, Tolerability and Pharmacokinetics of Single Doses of NTM-1633, a Novel Mixture of Monoclonal Antibodies against Botulinum Toxin E.
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  373. TARACILA MA, Bethel CR, Hujer AM, Papp-Wallace KM, et al
    Different Conformations Revealed by NMR Underlie Resistance to Ceftazidime/Avibactam and Susceptibility to Meropenem and Imipenem among D179Y Variants of KPC beta-Lactamase.
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  374. KUREPINA N, Chen L, Composto K, Rifat D, et al
    CRISPR Inhibition of Essential Peptidoglycan Biosynthesis Genes in Mycobacterium abscessus and Its Impact on beta-Lactam Susceptibility.
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  375. LIPORAGI LOPES LC, Korangath P, Dos Santos SR Jr, Gabrielson KL, et al
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  376. MOON SM, Kim SY, Kim DH, Huh HJ, et al
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  377. ANDRADE ESN, Brandao JG, Silva JSD, Coriolano CRF, et al
    Antimicrobial Resistance among Leprosy Patients in Brazil: Real-World Data Based on the National Surveillance Plan.
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  378. EICHENSEHER F, Herpers BL, Badoux P, Leyva-Castillo JM, et al
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  379. CAFFREY AR, Appaneal HJ, LaPlante KL, Lopes VV, et al
    Impact of Clopidogrel on Clinical Outcomes in Patients with Staphylococcus aureus Bacteremia: a National Retrospective Cohort Study.
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  380. GARCIA-PRATS AJ, Frias M, van der Laan L, De Leon A, et al
    Delamanid Added to an Optimized Background Regimen in Children with Multidrug-Resistant Tuberculosis: Results of a Phase I/II Clinical Trial.
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  381. CHAUHAN U, Barth VC, Woychik NA
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  382. ZHANG T, Yu X, Wen S, Xue Y, et al
    Bone Penetration of Cycloserine in Osteoarticular Tuberculosis Patients of China.
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    Genomic Screening of Antimicrobial Resistance Markers in UK and US Campylobacter Isolates Highlights Stability of Resistance over an 18-Year Period.
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    March 2022
  384. LIN X, Qin X, Wu X, Liao Y, et al
    Markedly Increasing Antibiotic Resistance and Dual Treatment of Neisseria gonorrhoeae Isolates in Guangdong, China, from 2013 to 2020.
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  385. SONG N, Zhou X, Li D, Li X, et al
    A Proteomic Landscape of Candida albicans in the Stepwise Evolution to Fluconazole Resistance.
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  386. LI J, Coste AT, Bachmann D, Sanglard D, et al
    Deciphering the Mrr1/Mdr1 Pathway in Azole Resistance of Candida auris.
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  387. TASNEEN R, Garcia A, Converse PJ, Zimmerman MD, et al
    Novel Regimens of Bedaquiline-Pyrazinamide Combined with Moxifloxacin, Rifabutin, Delamanid and/or OPC-167832 in Murine Tuberculosis Models.
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  388. JI X, Kruger H, Wang Y, Fessler AT, et al
    Tn560, a Novel Tn554 Family Transposon from Porcine Methicillin-Resistant Staphylococcus aureus ST398, Carries a Multiresistance Gene Cluster Comprising a Novel spc Gene Variant and the Genes lsa(E) and lnu(B).
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  390. ROTHSTEIN TE, Cunningham SA, Rieke RA, Mainella JM, et al
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  391. BILAL H, Tait JR, Lang Y, Zhou J, et al
    Simulated Intravenous versus Inhaled Tobramycin with or without Intravenous Ceftazidime Evaluated against Hypermutable Pseudomonas aeruginosa via a Dynamic Biofilm Model and Mechanism-Based Modeling.
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  394. KURBATFINSKI N, Goodman SD, Bakaletz LO
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  395. APPANEAL HJ, Lopes VV, LaPlante KL, Caffrey AR, et al
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  396. LI Y, Zhang L, Xiu L, Wang D, et al
    A Multiplex Molecular Assay for Detection of Six penA Codons To Predict Decreased Susceptibility to Cephalosporins in Neisseria gonorrhoeae.
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  397. SAWATZKY P, Demczuk W, Lefebvre B, Allen V, et al
    Increasing Azithromycin Resistance in Neisseria gonorrhoeae Due to NG-MAST 12302 Clonal Spread in Canada, 2015 to 2018.
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    Monoclonal Antibodies Targeting Surface-Exposed Epitopes of Candida albicans Cell Wall Proteins Confer In Vivo Protection in an Infection Model.
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    FadACB and smeU1VWU2X Contribute to Oxidative Stress-Mediated Fluoroquinolone Resistance in Stenotrophomonas maltophilia.
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    Spiropyrimidinetriones: a Class of DNA Gyrase Inhibitors with Activity against Mycobacterium tuberculosis and without Cross-Resistance to Fluoroquinolones.
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    Aspergillus terreus and the Interplay with Amphotericin B: from Resistance to Tolerance?
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    February 2022
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    Efficacy of Fluoroquinolones as Substitutes for Ethambutol or Rifampin in the Treatment of Mycobacterium avium Complex Pulmonary Disease According to Radiologic Types.
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  406. RUEDAS-LOPEZ A, Alonso-Garcia I, Lasarte-Monterrubio C, Guijarro-Sanchez P, et al
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  407. SELCHOW P, Ordway DJ, Verma D, Whittel N, et al
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  408. DAS S, Bush K
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    January 2022
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    Model-Based Meta-Analysis of Relapsing Mouse Model Studies from the Critical Path to Tuberculosis Drug Regimens Initiative Database.
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  414. KLINE A, Lionakis MS
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  415. DOMENECH P, Mouhoub E, Reed MB
    Experimental confirmation that an uncommon rrs gene mutation (g878a) of Mycobacterium tuberculosis confers resistance to streptomycin.
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    Factors associated with breakthrough fungemia caused by Candida, Trichosporon, or Fusarium species when the breakthrough fungemia developed in patients with hematological disorders.
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  418. BAO X, Bove M, Coenye T
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  419. CRANE SD, Banerjee SK, Pechous RD
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  420. PHAN JR, Do DM, Truong MC, Ngo C, et al
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  424. BONNET PL, Le Gal S, Hoffmann CV, Morio F, et al
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  428. EALES BM, Tam VH
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  429. ONG V, Wills S, Watson D, Sandison T, et al
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  433. SCHILDKRAUT JA, Coolen JPM, Burbaud S, Sangen JJN, et al
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  437. KILBURN S, Innes G, Quinn M, Southwick K, et al
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  438. VU BG, Moye-Rowley WS
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  439. WIRE MB, Jun SY, Jang IJ, Lee SH, et al
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    Genome analysis of Klebsiella oxytoca complex for antimicrobial resistance and virulence genes.
    Antimicrob Agents Chemother. 2022 Jan 10:aac0218321. doi: 10.1128/aac.02183.
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  441. SMELTER D, Hayney M, Sakoulas G, Rose W, et al
    Is the Success of Cefazolin plus Ertapenem in Methicillin-Susceptible Staphylococcus aureus Bacteremia Based on Release of Interleukin 1-beta?
    Antimicrob Agents Chemother. 2022 Jan 3:aac0216621. doi: 10.1128/aac.02166.
    >> Share

    December 2021
  442. NAKANO S, Fujisawa T, Chang B, Ito Y, et al
    Whole-genome analysis-based phylogeographic investigation of Streptococcus pneumoniae serotype 19A sequence type 320 isolates in Japan.
    Antimicrob Agents Chemother. 2021 Dec 20:AAC0139521. doi: 10.1128/AAC.01395.
    >> Share

  443. CAMARGO JF, Jabr R, Anderson AD, Lekakis L, et al
    Successful treatment of disseminated disease due to highly resistant Aspergillus calidoustus with a novel antifungal therapy.
    Antimicrob Agents Chemother. 2021 Dec 20:aac0220621. doi: 10.1128/aac.02206.
    >> Share

  444. TRUONG-BOLDUC QC, Wang Y, Reedy JL, Vyas JM, et al
    Staphylococcus aureus Efflux Pumps and Tolerance to Ciprofloxacin and Chlorhexidine following Induction by Mupirocin.
    Antimicrob Agents Chemother. 2021 Dec 20:AAC0184521. doi: 10.1128/AAC.01845.
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  445. CHEN Y, Moran JC, Campbell-Lee S, Horsburgh MJ, et al
    Transcriptomic responses and survival mechanisms of staphylococci to the antimicrobial skin lipid sphingosine.
    Antimicrob Agents Chemother. 2021 Dec 13:AAC0056921. doi: 10.1128/AAC.00569.
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  446. LACKNER N, Vahedi-Shahandashti R, Jahnig S, Schonherr L, et al
    Echinocandins and their Activity against Aspergillus terreus Species Complex: A Novel Agar Screening Method.
    Antimicrob Agents Chemother. 2021 Dec 13:AAC0190921. doi: 10.1128/AAC.01909.
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  447. HUANG J, Guo S, Li X, Yuan F, et al
    Nemonoxacin enhances antibacterial activity and anti-resistant mutation ability of vancomycin against methicillin-resistant Staphylococcus aureus in an in vitro dynamic pharmacokinetic/pharmacodynamic model.
    Antimicrob Agents Chemother. 2021 Dec 13:AAC0180021. doi: 10.1128/AAC.01800.
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  448. AGUIAR-ALVES F, Le HN, Tran VG, Gras E, et al
    Anti-virulence Bispecific Monoclonal Antibody Mediated Protection Against Pseudomonas aeruginosa Ventilator-Associated Pneumonia in a Rabbit Model.
    Antimicrob Agents Chemother. 2021 Dec 13:AAC0202221. doi: 10.1128/AAC.02022.
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  449. LYONS MA
    Pharmacodynamics and the Bactericidal Activity of Bedaquiline in Pulmonary Tuberculosis.
    Antimicrob Agents Chemother. 2021 Dec 6:AAC0163621. doi: 10.1128/AAC.01636.
    >> Share

  450. KIM JS, Kim YH, Lee SH, Kim YH, et al
    Early Bactericidal Activity of Delpazolid (LCB01-0371) in Patients with Pulmonary Tuberculosis.
    Antimicrob Agents Chemother. 2021 Dec 6:AAC0168421. doi: 10.1128/AAC.01684.
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  451. KHALIFA HO, Hubka V, Watanabe A, Nagi M, et al
    Prevalence of Antifungal Resistance, Genetic Basis of Acquired Azole and Echinocandin Resistance, and Genotyping of Candida krusei recovered from an International Collection.
    Antimicrob Agents Chemother. 2021 Dec 6:AAC0185621. doi: 10.1128/AAC.01856.
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  452. VERMA R, Gurumurthy M, Yeo BCM, Lu Q, et al
    Effects of increasing concentrations of rifampicin on different Mycobacterium tuberculosis lineages in a Whole blood Bactericidal Activity Assay.
    Antimicrob Agents Chemother. 2021 Dec 6:AAC0169921. doi: 10.1128/AAC.01699.
    >> Share

    November 2021
  453. POON R, Basuino L, Satishkumar N, Chatterjee A, et al
    Loss of GdpP function in Staphylococcus aureus leads to beta-lactam tolerance and enhanced evolution of beta-lactam resistance.
    Antimicrob Agents Chemother. 2021 Nov 29:AAC0143121. doi: 10.1128/AAC.01431.
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  454. SASAKI T, Svensson EM, Wang X, Wang Y, et al
    Population Pharmacokinetic and Concentration-QTc Analysis of Delamanid in Pediatric Participants with Multidrug-Resistant Tuberculosis.
    Antimicrob Agents Chemother. 2021 Nov 29:AAC0160821. doi: 10.1128/AAC.01608.
    >> Share

  455. CARVALHAES CG, Sader HS, Streit JM, Castanheira M, et al
    Activity of Oritavancin Against Gram-positive Pathogens Causing Bloodstream Infections in the United States Over 10 Years: Focus on Drug-Resistant Enterococcal Subsets (2010-2019).
    Antimicrob Agents Chemother. 2021 Nov 22:AAC0166721. doi: 10.1128/AAC.01667.
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  456. VOGENSEN VB, Bolhuis MS, Sturkenboom MGG, van der Werf TS, et al
    Clinical relevance of rifampicin-moxifloxacin interaction in isoniazid resistant/intolerant tuberculosis patients.
    Antimicrob Agents Chemother. 2021 Nov 22:AAC0182921. doi: 10.1128/AAC.01829.
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  457. WEI J, Tong K, Wang H, Wen Y, et al
    Intra-articular vancomycin for the prophylaxis of periprosthetic joint infection caused by methicillin-resistant S. aureus after total knee arthroplasty in a rat model: the dosage, efficacy, and safety.
    Antimicrob Agents Chemother. 2021 Nov 22:AAC0164121. doi: 10.1128/AAC.01641.
    >> Share

  458. LEE YL, Ko WC, Hsueh PR
    Geographic Patterns of Carbapenem-resistant Pseudomonas aeruginosa in the Asia-Pacific Region: Results from the Antimicrobial Testing Leadership and Surveillance (ATLAS) program, 2015-2019.
    Antimicrob Agents Chemother. 2021 Nov 22:AAC0200021. doi: 10.1128/AAC.02000.
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  459. CRANDON JL, Kuti JL, Nicolau DP
    Erratum for Crandon et al., "Comparative Efficacies of Human Simulated Exposures of Telavancin and Vancomycin against Methicillin-Resistant Staphylococcus aureus with a Range of Vancomycin MICs in a Murine Pneumonia Model".
    Antimicrob Agents Chemother. 2021;65:e0187821.
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  460. REITZEL RA, Rosenblatt J, Gerges BZ, Vargas-Cruz N, et al
    Erratum for Reitzel et al., "Minocycline-EDTA-Ethanol Antimicrobial Catheter Lock Solution Is Highly Effective In Vitro for Eradication of Candida auris Biofilms".
    Antimicrob Agents Chemother. 2021;65:e0198621.
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  461. NEWMAN LM, Kankam M, Nakamura A, Conrad T, et al
    Thorough QT Study To Evaluate the Effect of Zoliflodacin, a Novel Therapeutic for Gonorrhea, on Cardiac Repolarization in Healthy Adults.
    Antimicrob Agents Chemother. 2021;65:e0129221.
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  462. JOUSSET AB, Oueslati S, Emeraud C, Bonnin RA, et al
    KPC-39-Mediated Resistance to Ceftazidime-Avibactam in a Klebsiella pneumoniae ST307 Clinical Isolate.
    Antimicrob Agents Chemother. 2021;65:e0116021.
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  463. FIGUEIREDO ABC, Fonseca FL, Kuczera D, Conte FP, et al
    Monoclonal Antibodies against Cell Wall Chitooligomers as Accessory Tools for the Control of Cryptococcosis.
    Antimicrob Agents Chemother. 2021;65:e0118121.
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  464. KERKEZ I, Tulkens PM, Tenson T, Van Bambeke F, et al
    Uropathogenic Escherichia coli Shows Antibiotic Tolerance and Growth Heterogeneity in an In Vitro Model of Intracellular Infection.
    Antimicrob Agents Chemother. 2021;65:e0146821.
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  465. MUHLEN S, Zapol'skii VA, Bilitewski U, Dersch P, et al
    Identification of Translocation Inhibitors Targeting the Type III Secretion System of Enteropathogenic Escherichia coli.
    Antimicrob Agents Chemother. 2021;65:e0095821.
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  466. VANSCOY BD, Lakota EA, Conde H, Fikes S, et al
    Gepotidacin Pharmacokinetics-Pharmacodynamics against Escherichia coli in the One-Compartment and Hollow-Fiber In Vitro Infection Model Systems.
    Antimicrob Agents Chemother. 2021;65:e0012221.
    >> Share

  467. PEYRUSSON F, Whelan AO, Hartley MG, Norville IH, et al
    Intracellular Activity of Antibiotics against Coxiella burnetii in a Model of Activated Human THP-1 Cells.
    Antimicrob Agents Chemother. 2021;65:e0106121.
    >> Share

  468. KELLY MC, Yeager SD, Shorman MA, Wright LR, et al
    Incidence and Predictors of Gram-Negative Bacilli in Hospitalized People Who Inject Drugs with Injection Drug Use-Attributable Infections.
    Antimicrob Agents Chemother. 2021;65:e0092521.
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  469. SORAYAH R, Moraski GC, Barkan D, Pethe K, et al
    The QcrB Inhibitors TB47 and Telacebec Do Not Potentiate the Activity of Clofazimine in Mycobacterium abscessus.
    Antimicrob Agents Chemother. 2021;65:e0096421.
    >> Share

  470. MARTINS O, Lee J, Kaushik A, Ammerman NC, et al
    In Vitro Activity of Bedaquiline and Imipenem against Actively Growing, Nutrient-Starved, and Intracellular Mycobacterium abscessus.
    Antimicrob Agents Chemother. 2021;65:e0154521.
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  471. LI D, Sabato PE, Guiastrennec B, Ouerdani A, et al
    Population Pharmacokinetics, Exposure-Response, and Probability of Target Attainment Analyses for Tedizolid in Adolescent Patients with Acute Bacterial Skin and Skin Structure Infections.
    Antimicrob Agents Chemother. 2021;65:e0089521.
    >> Share

  472. SINGULANI JL, Oliveira LT, Ramos MD, Fregonezi NF, et al
    The Antimicrobial Peptide MK58911-NH2 Acts on Planktonic, Biofilm, and Intramacrophage Cells of Cryptococcus neoformans.
    Antimicrob Agents Chemother. 2021;65:e0090421.
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  473. SHARMA D, Paul RA, Rudramurthy SM, Kashyap N, et al
    Impact of FKS1 genotype on echinocandin in-vitro susceptibility in Candida auris and in-vivo response in a murine model of infection.
    Antimicrob Agents Chemother. 2021 Nov 15:AAC0165221. doi: 10.1128/AAC.01652.
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  474. NIIMI M, Niimi K, Tanabe K, Cannon RD, et al
    Inhibitor Resistant Mutants Give Important Insights into Candida albicans ABC Transporter Cdr1 Substrate Specificity and Help Elucidate Efflux Pump Inhibition.
    Antimicrob Agents Chemother. 2021 Nov 15:AAC0174821. doi: 10.1128/AAC.01748.
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  475. YAMAMURO R, Kimura M, Asano-Mori Y, Abe M, et al
    Clinical and microbiological characteristics of proven invasive aspergillosis due to rare/cryptic species in allogeneic hematopoietic stem cell transplant recipients.
    Antimicrob Agents Chemother. 2021 Nov 15:AAC0163021. doi: 10.1128/AAC.01630.
    >> Share

  476. YU JF, Xu JT, Yang SS, Gao MN, et al
    Decreased methylenetetrahydrofolate reductase activity leads to increased sensitivity to para-aminosalicylic acid in Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2021 Nov 15:AAC0146521. doi: 10.1128/AAC.01465.
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  477. RIVAS L, Alcalde-Rico M, Martinez JR, Moreno V, et al
    Real-world Performance of Susceptibility Testing for Ceftolozane/Tazobactam Against Non-Carbapenemase-Producing Carbapenem-Resistant Pseudomonas aeruginosa.
    Antimicrob Agents Chemother. 2021 Nov 15:AAC0165721. doi: 10.1128/AAC.01657.
    >> Share

  478. PHAN MD, Peters KM, Alvarez Fraga L, Wallis SC, et al
    Plasmid-mediated ciprofloxacin resistance imparts a selective advantage on Escherichia coli ST131.
    Antimicrob Agents Chemother. 2021 Nov 15:AAC0214621. doi: 10.1128/AAC.02146.
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  479. LIAO YS, Chen BH, Teng RH, Wang YW, et al
    Antimicrobial resistance in Campylobacter coli and Campylobacter jejuni from human campylobacteriosis in Taiwan, 2016-2019.
    Antimicrob Agents Chemother. 2021 Nov 8:AAC0173621. doi: 10.1128/AAC.01736.
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  480. MORRISETTE T, Lev KL, Canfield GS, Duerkop BA, et al
    Evaluation of Bacteriophage Cocktails Alone and in Combination with Daptomycin Against Daptomycin-Nonsusceptible Enterococcus faecium.
    Antimicrob Agents Chemother. 2021 Nov 1:AAC0162321. doi: 10.1128/AAC.01623.
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  481. KARAU MJ, Schmidt-Malan SM, Cunningham SA, Mandrekar JN, et al
    Activity of Omadacycline in Rat Methicillin-Resistant Staphylococcus aureus Osteomyelitis.
    Antimicrob Agents Chemother. 2021 Nov 1:AAC0170321. doi: 10.1128/AAC.01703.
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    October 2021
  482. HERREN SC, Huemer M, Acevedo CT, Gomez-Mejia A, et al
    Assessing antibiotic tolerance of Staphylococcus aureus derived directly from patients by the Replica Plating Tolerance Isolation System - REPTIS.
    Antimicrob Agents Chemother. 2021 Oct 25:AAC0096721. doi: 10.1128/AAC.00967.
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  483. ANAHTAR MN, Bramante JT, Xu J, Desrosiers LA, et al
    Prediction of antimicrobial resistance in clinical Enterococcus faecium isolates using a rules-based analysis of whole genome sequences.
    Antimicrob Agents Chemother. 2021 Oct 25:AAC0119621. doi: 10.1128/AAC.01196.
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  484. BUTCHER MC, Brown JL, Hansom D, Wilson-Van Os R, et al
    Antifungal loaded calcium sulfate beads as a potential therapeutic in combating Candida auris.
    Antimicrob Agents Chemother. 2021 Oct 25:AAC0171321. doi: 10.1128/AAC.01713.
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  485. MISHRA NN, Lew C, Abdelhady W, Lapitan CK, et al
    Synergy Mechanisms of Daptomycin-Fosfomycin Combinations in Daptomycin-Susceptible and -Resistant Methicillin-Resistant S. aureus: In vitro, Ex vivo and In vivo Metrics.
    Antimicrob Agents Chemother. 2021 Oct 25:AAC0164921. doi: 10.1128/AAC.01649.
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  486. DEMCZUK W, Martin I, Griffith A, Lefebvre B, et al
    Linear regression equations to predict beta-lactam, macrolide, lincosamide and fluoroquinolone minimum inhibitory concentrations from molecular antimicrobial resistance determinants in Streptococcus pneumoniae.
    Antimicrob Agents Chemother. 2021 Oct 18:AAC0137021. doi: 10.1128/AAC.01370.
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  487. BAKLOUTI S, Marolleau S, Chavanet P, Bonnet E, et al
    Letter to the Editor on: "Population Pharmacokinetics of Dalbavancin and Dosing Considerations for Optimal Treatment of Adult Patients with Staphylococcal Osteoarticular Infections".
    Antimicrob Agents Chemother. 2021 Oct 18:AAC0149321. doi: 10.1128/AAC.01493.
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  488. CAFLISCH KM, Patel R
    Phage Activity Against Planktonic and Biofilm Staphylococcus aureus Periprosthetic Joint Infection Isolates.
    Antimicrob Agents Chemother. 2021 Oct 18:AAC0187921. doi: 10.1128/AAC.01879.
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  489. JIANG S, Zhuang H, Zhu F, Wei X, et al
    The role of mprF mutations in "see-saw effect" of Daptomycin-resistant methicillin-resistant Staphylococcus aureus isolates.
    Antimicrob Agents Chemother. 2021 Oct 18:AAC0129521. doi: 10.1128/AAC.01295.
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  490. BAGHDADI JD, Coffey KC, Adediran T, Goodman KE, et al
    Antibiotic Use and Bacterial Infection among Inpatients in the First Wave of COVID-19: a Retrospective Cohort Study of 64,691 Patients.
    Antimicrob Agents Chemother. 2021;65:e0134121.
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  491. SHORTRIDGE D, Arends SJR, Streit JM, Castanheira M, et al
    Minocycline Activity against Unusual Clinically Significant Gram-Negative Pathogens.
    Antimicrob Agents Chemother. 2021;65:e0126421.
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  492. TALLEY AK, Thurston A, Moore G, Gupta VK, et al
    First-in-Human Evaluation of the Safety, Tolerability, and Pharmacokinetics of SPR720, a Novel Oral Bacterial DNA Gyrase (GyrB) Inhibitor for Mycobacterial Infections.
    Antimicrob Agents Chemother. 2021;65:e0120821.
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  493. FONTANA H, Cardoso B, Esposito F, de Lima AV, et al
    Small IncQ1 Plasmid Encoding KPC-2 Expands to Invasive Nontyphoidal Salmonella.
    Antimicrob Agents Chemother. 2021;65:e0155221.
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  494. GUO Q, Xu L, Tan F, Zhang Y, et al
    A Novel Oxazolidinone, Contezolid (MRX-I), Expresses Anti-Mycobacterium abscessus Activity In Vitro.
    Antimicrob Agents Chemother. 2021;65:e0088921.
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  495. KOMM O, Almeida DV, Converse PJ, Omansen TF, et al
    Impact of Dose, Duration, and Immune Status on Efficacy of Ultrashort Telacebec Regimens in Mouse Models of Buruli Ulcer.
    Antimicrob Agents Chemother. 2021;65:e0141821.
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  496. BANERJEE R, Cunningham SA, Beisken S, Posch AE, et al
    Core Genome Multilocus Sequence Typing and Prediction of Antimicrobial Susceptibility Using Whole-Genome Sequences of Escherichia coli Bloodstream Infection Isolates.
    Antimicrob Agents Chemother. 2021;65:e0113921.
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  497. RUBINO CM, Flanagan S
    Population Pharmacokinetics of Rezafungin in Patients with Fungal Infections.
    Antimicrob Agents Chemother. 2021;65:e0084221.
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  498. LOVEY A, Krel M, Borchardt A, Brady T, et al
    Development of Novel Immunoprophylactic Agents against Multidrug-Resistant Gram-Negative Bacterial Infections.
    Antimicrob Agents Chemother. 2021;65:e0098521.
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  499. STOTT KE, Le T, Nguyen T, Whalley S, et al
    Population Pharmacokinetics and Pharmacodynamics of Itraconazole for Disseminated Infection Caused by Talaromyces marneffei.
    Antimicrob Agents Chemother. 2021;65:e0063621.
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  500. CLAY KA, Hartley MG, Armstrong S, Bewley KR, et al
    Evaluation of the Efficacy of Doxycycline, Ciprofloxacin, Levofloxacin, and Co-trimoxazole Using In Vitro and In Vivo Models of Q Fever.
    Antimicrob Agents Chemother. 2021;65:e0067321.
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  501. ZAIDAN N, Hornak JP, Reynoso D
    Extensively Drug-Resistant Acinetobacter baumannii Nosocomial Pneumonia Successfully Treated with a Novel Antibiotic Combination.
    Antimicrob Agents Chemother. 2021;65:e0092421.
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  502. CUBRIA MB, Vega LA, Shropshire WC, Sanson MA, et al
    Population genomics reveals distinct temporal association with the emergence of ST1 serotype V Group B Streptococcus and macrolide resistance in North America.
    Antimicrob Agents Chemother. 2021 Oct 11:AAC0071421. doi: 10.1128/AAC.00714.
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  503. WILLIAMSON B, Wilk A, Guerrero KD, Mikulski TD, et al
    Impact of Erg11 amino acid substitutions identified in Candida auris clade III isolates on triazole drug susceptibility.
    Antimicrob Agents Chemother. 2021 Oct 11:AAC0162421. doi: 10.1128/AAC.01624.
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  504. EVERT BJ, Slesarenko VA, Punnasseril JMJ, Taha, et al
    Self-inhibitory peptides targeting the Neisseria gonorrhoeae MtrCDE efflux pump increase antibiotic susceptibility.
    Antimicrob Agents Chemother. 2021 Oct 11:AAC0154221. doi: 10.1128/AAC.01542.
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  505. GANAPATHY US, Del Rio RG, Cacho-Izquierdo M, Ortega F, et al
    A Mycobacterium tuberculosis NBTI DNA gyrase inhibitor is active against Mycobacterium abscessus.
    Antimicrob Agents Chemother. 2021 Oct 4:AAC0151421. doi: 10.1128/AAC.01514.
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  506. JACQUELINE C, Caillon J, Meyer O, Dailly E, et al
    Efficacy of Nano-Encapsulated Daptomycin in an Experimental Methicillin-Resistant Staphylococcus aureus (MRSA) Bone and Joint Infection Model.
    Antimicrob Agents Chemother. 2021 Oct 4:AAC0076821. doi: 10.1128/AAC.00768.
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  507. RADTKE KK, Ernest JP, Zhang N, Ammerman NC, et al
    Comparative efficacy of rifapentine alone and in combination with isoniazid for latent tuberculosis infection: a translational pharmacokinetic-pharmacodynamic modelling study.
    Antimicrob Agents Chemother. 2021 Oct 4:AAC0170521. doi: 10.1128/AAC.01705.
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  508. IKEDA T, Suzuki R, Jin W, Wachino JI, et al
    Isolation of Group A Streptococci with Reduced In Vitro beta-Lactam Susceptibility Harboring Amino Acid Substitutions in Penicillin-Binding Proteins in Japan.
    Antimicrob Agents Chemother. 2021 Oct 4:AAC0148221. doi: 10.1128/AAC.01482.
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    September 2021
  509. DIAZ-GARCIA J, Mesquida A, Gomez A, Machado M, et al
    Antifungal susceptibility testing identifies the abdominal cavity as a source of Candida glabrata resistant isolates.
    Antimicrob Agents Chemother. 2021 Sep 27:AAC0124921. doi: 10.1128/AAC.01249.
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  510. ALMEIDA D, Converse PJ, Li SY, Upton AM, et al
    Comparative efficacy of the novel diarylquinoline TBAJ-876 and bedaquiline against a resistant Rv0678 mutant in a mouse model of tuberculosis.
    Antimicrob Agents Chemother. 2021 Sep 27:AAC0141221. doi: 10.1128/AAC.01412.
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  511. INGLE DJ, Andersson P, Valcanis M, Wilmot M, et al
    Genomic epidemiology and antimicrobial resistance mechanisms of imported typhoid in Australia.
    Antimicrob Agents Chemother. 2021 Sep 20:AAC0120021. doi: 10.1128/AAC.01200.
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    August 2021
  512. HOWARD-ANDERSON J, van Duin D
    Uncertainty in evaluating treatment outcomes in carbapenem-resistant Acinetobacter baumannii infections.
    Antimicrob Agents Chemother. 2021 Aug 23:AAC0142421. doi: 10.1128/AAC.01424.
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  513. MUKHERJEE S, Blankenship HM, Rodrigues JA, Mosci RE, et al
    Antibiotic susceptibility profiles and frequency of resistance genes in clinical Shiga toxin-producing Escherichia coli isolates from Michigan over a 14-year period.
    Antimicrob Agents Chemother. 2021 Aug 23:AAC0118921. doi: 10.1128/AAC.01189.
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  514. GILL CM, Aktathorn E, Alfouzan W, Bourassa L, et al
    Elevated MICs of Susceptible Anti-Pseudomonal Cephalosporins in Non-Carbapenemase-Producing, Carbapenem-Resistant Pseudomonas aeruginosa: Implications for Dose Optimization.
    Antimicrob Agents Chemother. 2021 Aug 16:AAC0120421. doi: 10.1128/AAC.01204.
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  515. NGWALERO P, Brust JCM, van Beek SW, Wasserman S, et al
    Relationship between plasma and intracellular concentrations of bedaquiline and its M2 metabolite in South African patients with rifampin-resistant TB.
    Antimicrob Agents Chemother. 2021 Aug 9:AAC0239920. doi: 10.1128/AAC.02399.
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  516. GUTIERREZ-GUTIERREZ B, Perez-Nadales E, Perez-Galera S, Fernandez-Ruiz M, et al
    Ertapenem for treatment of non-severe bacteremic urinary-tract infections due to ESBL-producing Enterobacterales in kidney transplant recipients: a propensity score and DOOR-based analysis.
    Antimicrob Agents Chemother. 2021 Aug 9:AAC0110221. doi: 10.1128/AAC.01102.
    >> Share


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