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Bacterial Infections and Mycoses

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Articles published in
PLoS Pathog
    June 2024
  1. CULLUM E, Perez-Betancourt Y, Shi M, Gkika E, et al
    Deficiency in non-classical major histocompatibility class II-like molecule, H2-O confers protection against Staphylococcus aureus in mice.
    PLoS Pathog. 2024;20:e1012306.
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  2. DULYAYANGKUL P, Beavis T, Lee WWY, Ardagh R, et al
    Harvesting and amplifying gene cassettes confers cross-resistance to critically important antibiotics.
    PLoS Pathog. 2024;20:e1012235.
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    May 2024
  3. XIONG L, Pereira De Sa N, Zarnowski R, Huang MY, et al
    Biofilm-associated metabolism via ERG251 in Candida albicans.
    PLoS Pathog. 2024;20:e1012225.
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  4. ZHENG W, Chang IC, Limberis J, Budzik JM, et al
    Mycobacterium tuberculosis resides in lysosome-poor monocyte-derived lung cells during chronic infection.
    PLoS Pathog. 2024;20:e1012205.
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  5. WINDELS EM, Wampande EM, Joloba ML, Boom WH, et al
    HIV co-infection is associated with reduced Mycobacterium tuberculosis transmissibility in sub-Saharan Africa.
    PLoS Pathog. 2024;20:e1011675.
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  6. JIANG B, Lai Y, Xiao W, Zhong T, et al
    Microbial extracellular vesicles contribute to antimicrobial resistance.
    PLoS Pathog. 2024;20:e1012143.
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  7. VANKAYALAPATI A, Durojaye O, Mukherjee T, Paidipally P, et al
    Metabolic changes enhance necroptosis of type 2 diabetes mellitus mice infected with Mycobacterium tuberculosis.
    PLoS Pathog. 2024;20:e1012148.
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  8. ZANG X, Zhang J, Jiang Y, Feng T, et al
    Serine protease Rv2569c facilitates transmission of Mycobacterium tuberculosis via disrupting the epithelial barrier by cleaving E-cadherin.
    PLoS Pathog. 2024;20:e1012214.
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  9. LOKKEN-TOYLI KL, Aggarwal SD, Bee GCW, de Steenhuijsen Piters WAA, et al
    Impaired upper respiratory tract barrier function during postnatal development predisposes to invasive pneumococcal disease.
    PLoS Pathog. 2024;20:e1012111.
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  10. BAI Y, Xie C, Zhang Y, Zhang Z, et al
    sRNA expression profile of KPC-2-producing carbapenem-resistant Klebsiella pneumoniae: Functional role of sRNA51.
    PLoS Pathog. 2024;20:e1012187.
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  11. BARNES AJ, Bennett EF, Vezina B, Hudson AW, et al
    Ethanolamine metabolism through two genetically distinct loci enables Klebsiella pneumoniae to bypass nutritional competition in the gut.
    PLoS Pathog. 2024;20:e1012189.
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  12. WACKER T, Helmstetter N, Studholme DJ, Farrer RA, et al
    Genome variation in the Batrachochytrium pathogens of amphibians.
    PLoS Pathog. 2024;20:e1012218.
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  13. LIANG Y, Wang H, Sun K, Sun J, et al
    Lack of the IFN-gamma signal leads to lethal Orientia tsutsugamushi infection in mice with skin eschar lesions.
    PLoS Pathog. 2024;20:e1012020.
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  14. DICANDIA MA, Edwards AN, Alcaraz YB, Monteiro MP, et al
    A conserved switch controls virulence, sporulation, and motility in C. difficile.
    PLoS Pathog. 2024;20:e1012224.
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  15. LI C, Fu J, Shao S, Luo ZQ, et al
    Legionella pneumophila exploits the endo-lysosomal network for phagosome biogenesis by co-opting SUMOylated Rab7.
    PLoS Pathog. 2024;20:e1011783.
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  16. WILLIAMS SL, Toda M, Chiller T, Brunkard JM, et al
    Effects of climate change on fungal infections.
    PLoS Pathog. 2024;20:e1012219.
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  17. PAN Q, Zhang Y, Liu T, Xu Q, et al
    Mycoplasma glycine cleavage system key subunit GcvH is an apoptosis inhibitor targeting host endoplasmic reticulum.
    PLoS Pathog. 2024;20:e1012266.
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    April 2024
  18. SANGKLAI N, Supungul P, Jaroenlak P, Tassanakajon A, et al
    Immune signaling of Litopenaeus vannamei c-type lysozyme and its role during microsporidian Enterocytozoon hepatopenaei (EHP) infection.
    PLoS Pathog. 2024;20:e1012199.
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  19. GU Q, Zhu X, Yu Y, Jiang T, et al
    Type II and IV toxin-antitoxin systems coordinately stabilize the integrative and conjugative element of the ICESa2603 family conferring multiple drug resistance in Streptococcus suis.
    PLoS Pathog. 2024;20:e1012169.
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  20. YOUNGBLOM MA, Smith TM, Murray HJ, Pepperell CS, et al
    Adaptation of the Mycobacterium tuberculosis transcriptome to biofilm growth.
    PLoS Pathog. 2024;20:e1012124.
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  21. LI J, Ma Q, Huang J, Liu Y, et al
    Small RNA SmsR1 modulates acidogenicity and cariogenic virulence by affecting protein acetylation in Streptococcus mutans.
    PLoS Pathog. 2024;20:e1012147.
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  22. BOBBA S, Chauhan KS, Akter S, Das S, et al
    A protective role for type I interferon signaling following infection with Mycobacterium tuberculosis carrying the rifampicin drug resistance-conferring RpoB mutation H445Y.
    PLoS Pathog. 2024;20:e1012137.
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  23. GNAIEN M, Maufrais C, Rebai Y, Kallel A, et al
    A gain-of-function mutation in zinc cluster transcription factor Rob1 Drives Candida albicans adaptive growth in the cystic fibrosis lung environment.
    PLoS Pathog. 2024;20:e1012154.
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  24. FULLER NM, McQuaid CF, Harker MJ, Weerasuriya CK, et al
    Mathematical models of drug-resistant tuberculosis lack bacterial heterogeneity: A systematic review.
    PLoS Pathog. 2024;20:e1011574.
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  25. CALDERON-GONZALEZ R, Dumigan A, Sa-Pessoa J, Kissenpfennig A, et al
    In vivo single-cell high-dimensional mass cytometry analysis to track the interactions between Klebsiella pneumoniae and myeloid cells.
    PLoS Pathog. 2024;20:e1011900.
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  26. FAITH DR, Kinnersley M, Brooks DM, Drecktrah D, et al
    Characterization and genomic analysis of the Lyme disease spirochete bacteriophage varphiBB-1.
    PLoS Pathog. 2024;20:e1012122.
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    March 2024
  27. BLOCK AM, Wiegert PC, Namugenyi SB, Tischler AD, et al
    Transposon sequencing reveals metabolic pathways essential for Mycobacterium tuberculosis infection.
    PLoS Pathog. 2024;20:e1011663.
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  28. PELLETIER C, Shaw S, Alsayegh S, Brown AJP, et al
    Candida auris undergoes adhesin-dependent and -independent cellular aggregation.
    PLoS Pathog. 2024;20:e1012076.
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  29. SHANNON BA, Hurst JR, Flannagan RS, Craig HC, et al
    Streptolysin S is required for Streptococcus pyogenes nasopharyngeal and skin infection in HLA-transgenic mice.
    PLoS Pathog. 2024;20:e1012072.
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  30. KURTZ SL, Baker RE, Boehm FJ, Lehman CC, et al
    Multiple genetic loci influence vaccine-induced protection against Mycobacterium tuberculosis in genetically diverse mice.
    PLoS Pathog. 2024;20:e1012069.
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  31. SPRAGUE JL, Schille TB, Allert S, Trumper V, et al
    Candida albicans translocation through the intestinal epithelial barrier is promoted by fungal zinc acquisition and limited by NFkappaB-mediated barrier protection.
    PLoS Pathog. 2024;20:e1012031.
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  32. SANTANA DJ, Zhao G, O'Meara TR
    The many faces of Candida auris: Phenotypic and strain variation in an emerging pathogen.
    PLoS Pathog. 2024;20:e1012011.
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    Renaming Candida glabrata-A case of taxonomic purity over clinical and public health pragmatism.
    PLoS Pathog. 2024;20:e1012055.
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  34. ANGGRAMUKTI DS, Ishii E, Pratama A, Al Kadi M, et al
    The read-through transcription-mediated autoactivation circuit for virulence regulator expression drives robust type III secretion system 2 expression in Vibrio parahaemolyticus.
    PLoS Pathog. 2024;20:e1012094.
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    February 2024
  35. STANLEY S, Wang X, Liu Q, Kwon YY, et al
    Ongoing evolution of the Mycobacterium tuberculosis lactate dehydrogenase reveals the pleiotropic effects of bacterial adaption to host pressure.
    PLoS Pathog. 2024;20:e1012050.
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  36. NGUYEN TT, Kim TH, Bencosme-Cuevas E, Berry J, et al
    A tick saliva serpin, IxsS17 inhibits host innate immune system proteases and enhances host colonization by Lyme disease agent.
    PLoS Pathog. 2024;20:e1012032.
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    January 2024
  37. MERCADO MAB, Li Q, Quick CM, Kim Y, et al
    BHLHE40 drives protective polyfunctional CD4 T cell differentiation in the female reproductive tract against Chlamydia.
    PLoS Pathog. 2024;20:e1011983.
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  38. SHIELDS KE, Ranava D, Tan Y, Zhang D, et al
    Epitranscriptional m6A modification of rRNA negatively impacts translation and host colonization in Staphylococcus aureus.
    PLoS Pathog. 2024;20:e1011968.
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  39. DOLBEC D, Lehoux M, de Beauville AA, Zahn A, et al
    Unmutated but T cell dependent IgM antibodies targeting Streptococcus suis play an essential role in bacterial clearance.
    PLoS Pathog. 2024;20:e1011957.
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  40. BEETHAM CM, Schuster CF, Kviatkovski I, Santiago M, et al
    Histidine transport is essential for the growth of Staphylococcus aureus at low pH.
    PLoS Pathog. 2024;20:e1011927.
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  41. WANG Z, Jiang Z, Zhang Y, Wang C, et al
    Exosomes derived from bladder epithelial cells infected with uropathogenic Escherichia coli increase the severity of urinary tract infections (UTIs) by impairing macrophage function.
    PLoS Pathog. 2024;20:e1011926.
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  42. RIXON JA, Fong KD, Morris C, Nguyen AT, et al
    Elimination of Chlamydia muridarum from the female reproductive tract is IL-12p40 dependent, but independent of Th1 and Th2 cells.
    PLoS Pathog. 2024;20:e1011914.
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  43. ZHAO G, Li Y, Chen T, Liu F, et al
    TRIM26 alleviates fatal immunopathology by regulating inflammatory neutrophil infiltration during Candida infection.
    PLoS Pathog. 2024;20:e1011902.
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  44. LIN XQ, Liu ZZ, Zhou CK, Zhang L, et al
    Trained immunity in recurrent Staphylococcus aureus infection promotes bacterial persistence.
    PLoS Pathog. 2024;20:e1011918.
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  45. MAI D, Jahn A, Murray T, Morikubo M, et al
    Exposure to Mycobacterium remodels alveolar macrophages and the early innate response to Mycobacterium tuberculosis infection.
    PLoS Pathog. 2024;20:e1011871.
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  46. WU Z, Yang S, Fang X, Shu Q, et al
    Function and mechanism of TREM2 in bacterial infection.
    PLoS Pathog. 2024;20:e1011895.
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  47. SONG Y, Zhang S, Zhao N, Nong C, et al
    Pseudomonas aeruginosa two-component system CprRS regulates HigBA expression and bacterial cytotoxicity in response to LL-37 stress.
    PLoS Pathog. 2024;20:e1011946.
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  48. BRADY A, Sheneman KR, Pulsifer AR, Price SL, et al
    Type 3 secretion system induced leukotriene B4 synthesis by leukocytes is actively inhibited by Yersinia pestis to evade early immune recognition.
    PLoS Pathog. 2024;20:e1011280.
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    December 2023
  49. ZHANG W, Sun C, Lang H, Wang J, et al
    Toll receptor ligand Spatzle 4 responses to the highly pathogenic Enterococcus faecalis from Varroa mites in honeybees.
    PLoS Pathog. 2023;19:e1011897.
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  50. GANSER C, Staples MI, Dowell M, Frazer C, et al
    Filamentation and biofilm formation are regulated by the phase-separation capacity of network transcription factors in Candida albicans.
    PLoS Pathog. 2023;19:e1011833.
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  51. HORTON MV, Holt AM, Nett JE
    Mechanisms of pathogenicity for the emerging fungus Candida auris.
    PLoS Pathog. 2023;19:e1011843.
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  52. PALMUCCI JR, Messina JA, Tenor JL, Perfect JR, et al
    New anticancer therapeutics impact fungal pathobiology, infection dynamics, and outcome.
    PLoS Pathog. 2023;19:e1011845.
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  53. CREMIN M, Tay EXY, Ramirez VT, Murray K, et al
    TRPV1 controls innate immunity during Citrobacter rodentium enteric infection.
    PLoS Pathog. 2023;19:e1011576.
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  54. SABBIONE F, Keitelman IA, Shiromizu CM, Vereertbrugghen A, et al
    Regulation of human neutrophil IL-1beta secretion induced by Escherichia coli O157:H7 responsible for hemolytic uremic syndrome.
    PLoS Pathog. 2023;19:e1011877.
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  55. PETNICKI-OCWIEJA T, McCarthy JE, Powale U, Langston PK, et al
    Borrelia burgdorferi initiates early transcriptional re-programming in macrophages that supports long-term suppression of inflammation.
    PLoS Pathog. 2023;19:e1011886.
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    November 2023
  56. PLUMLEE CR, Barrett HW, Shao DE, Lien KA, et al
    Assessing vaccine-mediated protection in an ultra-low dose Mycobacterium tuberculosis murine model.
    PLoS Pathog. 2023;19:e1011825.
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  57. BAO L, Sun H, Zhao Y, Feng L, et al
    Hexadecanamide alleviates Staphylococcus aureus-induced mastitis in mice by inhibiting inflammatory responses and restoring blood-milk barrier integrity.
    PLoS Pathog. 2023;19:e1011764.
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  58. SILAO FGS, Jiang T, Bereczky-Veress B, Kuhbacher A, et al
    Proline catabolism is a key factor facilitating Candida albicans pathogenicity.
    PLoS Pathog. 2023;19:e1011677.
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  59. SUZUKI T, Boonyaleka K, Okano T, Iida T, et al
    Inflammasome-triggered IL-18 controls skin inflammation in the progression of Buruli ulcer.
    PLoS Pathog. 2023;19:e1011747.
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  60. CARRENO-FLOREZ GP, Kocak BR, Hendricks MR, Melvin JA, et al
    Interferon signaling drives epithelial metabolic reprogramming to promote secondary bacterial infection.
    PLoS Pathog. 2023;19:e1011719.
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  61. SAN JUAN GALAN J, Poliquin V, Gerstein AC
    Insights and advances in recurrent vulvovaginal candidiasis.
    PLoS Pathog. 2023;19:e1011684.
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  62. WANG J, Duan Z, Zeng R, Yang L, et al
    Antimicrobial peptide-producing dermal preadipocytes defend against Candida albicans skin infection via the FGFR-MEK-ERK pathway.
    PLoS Pathog. 2023;19:e1011754.
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  63. SAUTERS TJC, Roth C, Murray D, Sun S, et al
    Amoeba predation of Cryptococcus: A quantitative and population genomic evaluation of the accidental pathogen hypothesis.
    PLoS Pathog. 2023;19:e1011763.
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  64. SHARMA AK, El Andaloussi A, Ismail N
    Evasion of host antioxidative response via disruption of NRF2 signaling in fatal Ehrlichia-induced liver injury.
    PLoS Pathog. 2023;19:e1011791.
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  65. DE CASTRO RJA, Marina CL, Sturny-Leclere A, Hoffmann C, et al
    Kicking sleepers out of bed: Macrophages promote reactivation of dormant Cryptococcus neoformans by extracellular vesicle release and non-lytic exocytosis.
    PLoS Pathog. 2023;19:e1011841.
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  66. SZE CW, Zhang K, Lynch MJ, Iyer R, et al
    A chemosensory-like histidine kinase is dispensable for chemotaxis in vitro but regulates the virulence of Borrelia burgdorferi through modulating the stability of RpoS.
    PLoS Pathog. 2023;19:e1011752.
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    October 2023
  67. KAMATH MM, Lightfoot JD, Adams EM, Kiser RM, et al
    The Aspergillus fumigatus UPR is variably activated across nutrient and host environments and is critical for the establishment of corneal infection.
    PLoS Pathog. 2023;19:e1011435.
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  68. DUGGAN S, Usher J
    Candida glabrata: A powerhouse of resistance.
    PLoS Pathog. 2023;19:e1011651.
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  69. CARTY J, Chowdhary A, Bernstein D, Thangamani S, et al
    Tools and techniques to identify, study, and control Candida auris.
    PLoS Pathog. 2023;19:e1011698.
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  70. CHOI JT, Choi Y, Lee Y, Lee SH, et al
    The hybrid RAVE complex plays V-ATPase-dependent and -independent pathobiological roles in Cryptococcus neoformans.
    PLoS Pathog. 2023;19:e1011721.
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    September 2023
  71. ONEISSI M, Cruz MR, Ramirez-Zavala B, Lindemann-Perez E, et al
    Host-derived reactive oxygen species trigger activation of the Candida albicans transcription regulator Rtg1/3.
    PLoS Pathog. 2023;19:e1011692.
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  72. DE MIRANDA R, Cuthbert BJ, Klevorn T, Chao A, et al
    Differentiating the roles of Mycobacterium tuberculosis substrate binding proteins, FecB and FecB2, in iron uptake.
    PLoS Pathog. 2023;19:e1011650.
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  73. GREEN AE, Pottenger S, Monshi MS, Barton TE, et al
    Airway metabolic profiling during Streptococcus pneumoniae infection identifies branched chain amino acids as signatures of upper airway colonisation.
    PLoS Pathog. 2023;19:e1011630.
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  74. PALCEKOVA Z, Obregon-Henao A, De K, Walz A, et al
    Role of succinyl substituents in the mannose-capping of lipoarabinomannan and control of inflammation in Mycobacterium tuberculosis infection.
    PLoS Pathog. 2023;19:e1011636.
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  75. DAY AW, Kumamoto CA
    Interplay between host and Candida albicans during commensal gut colonization.
    PLoS Pathog. 2023;19:e1011607.
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  76. JOHNSON K, Delaney JC, Guillard T, Reffuveille F, et al
    Development of an antibody fused with an antimicrobial peptide targeting Pseudomonas aeruginosa: A new approach to prevent and treat bacterial infections.
    PLoS Pathog. 2023;19:e1011612.
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  77. WANG N, Scott TA, Kupz A, Shreenivas MM, et al
    Vaccine-induced inflammation and inflammatory monocytes promote CD4+ T cell-dependent immunity against murine salmonellosis.
    PLoS Pathog. 2023;19:e1011666.
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  78. DADELAHI AS, Abushahba MFN, Ponzilacqua-Silva B, Chambers CA, et al
    Interactions between B cells and T follicular regulatory cells enhance susceptibility to Brucella infection independent of the anti-Brucella humoral response.
    PLoS Pathog. 2023;19:e1011672.
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    August 2023
  79. PHAN QT, Solis NV, Cravener MV, Swidergall M, et al
    Candida albicans stimulates formation of a multi-receptor complex that mediates epithelial cell invasion during oropharyngeal infection.
    PLoS Pathog. 2023;19:e1011579.
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  80. CABRERA K, Hoard DS, Gibson O, Martinez DI, et al
    Drosophila immune priming to Enterococcus faecalis relies on immune tolerance rather than resistance.
    PLoS Pathog. 2023;19:e1011567.
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  81. SENA BAG, Jozefowicz LJ, Rodrigues ML
    More complicated than it seems: The diversity of cryptococcal glucuronoxylomannan.
    PLoS Pathog. 2023;19:e1011521.
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  82. ZHU J, Abruzzo AR, Wu C, Bee GCW, et al
    Effects of Capsular Polysaccharide amount on Pneumococcal-Host interactions.
    PLoS Pathog. 2023;19:e1011509.
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  83. HU YT, Wu KX, Wang XT, Zhao YY, et al
    Treponema pallidum promoted microglia apoptosis and prevented itself from clearing by human microglia via blocking autophagic flux.
    PLoS Pathog. 2023;19:e1011594.
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    Azole potentiation in Candida species.
    PLoS Pathog. 2023;19:e1011583.
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  85. LEMIEUX JE, Huang W, Hill N, Cerar T, et al
    Whole genome sequencing of human Borrelia burgdorferi isolates reveals linked blocks of accessory genome elements located on plasmids and associated with human dissemination.
    PLoS Pathog. 2023;19:e1011243.
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  86. KUMAR N, Pestrak MJ, Wu Q, Ahumada OS, et al
    Pseudomonas aeruginosa pulmonary infection results in S100A8/A9-dependent cardiac dysfunction.
    PLoS Pathog. 2023;19:e1011573.
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  87. ZINCK CB, Raveendram Thampy P, Uhlemann EE, Adam H, et al
    Variation among strains of Borrelia burgdorferi in host tissue abundance and lifetime transmission determine the population strain structure in nature.
    PLoS Pathog. 2023;19:e1011572.
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  88. VON STREMPEL A, Weiss AS, Wittmann J, Salvado Silva M, et al
    Bacteriophages targeting protective commensals impair resistance against Salmonella Typhimurium infection in gnotobiotic mice.
    PLoS Pathog. 2023;19:e1011600.
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    July 2023
  89. CAMARASA TMN, Torne J, Chevalier C, Rasid O, et al
    Streptococcus pneumoniae drives specific and lasting Natural Killer cell memory.
    PLoS Pathog. 2023;19:e1011159.
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  90. KIM J, Kim GL, Norambuena J, Boyd JM, et al
    Impact of the pentose phosphate pathway on metabolism and pathogenesis of Staphylococcus aureus.
    PLoS Pathog. 2023;19:e1011531.
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  91. LARCOMBE DE, Bohovych IM, Pradhan A, Ma Q, et al
    Glucose-enhanced oxidative stress resistance-A protective anticipatory response that enhances the fitness of Candida albicans during systemic infection.
    PLoS Pathog. 2023;19:e1011505.
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  92. WHITTINGTON AM, Turner FS, Baark F, Templeman S, et al
    An acidic microenvironment in Tuberculosis increases extracellular matrix degradation by regulating macrophage inflammatory responses.
    PLoS Pathog. 2023;19:e1011495.
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  93. DANIEL L, Counoupas C, Bhattacharyya ND, Triccas JA, et al
    L-selectin-dependent and -independent homing of naive lymphocytes through the lung draining lymph node support T cell response to pulmonary Mycobacterium tuberculosis infection.
    PLoS Pathog. 2023;19:e1011460.
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  94. VERBEKE J, De Bolle X, Arnould T
    To eat or not to eat mitochondria? How do host cells cope with mitophagy upon bacterial infection?
    PLoS Pathog. 2023;19:e1011471.
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  95. OSTERMANN L, Seeliger B, David S, Flasche C, et al
    S100A9 is indispensable for survival of pneumococcal pneumonia in mice.
    PLoS Pathog. 2023;19:e1011493.
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  96. MALAGA W, Payros D, Meunier E, Frigui W, et al
    Natural mutations in the sensor kinase of the PhoPR two-component regulatory system modulate virulence of ancestor-like tuberculosis bacilli.
    PLoS Pathog. 2023;19:e1011437.
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  97. DEBOWSKI AW, Bzdyl NM, Thomas DR, Scott NE, et al
    Macrophage infectivity potentiator protein, a peptidyl prolyl cis-trans isomerase, essential for Coxiella burnetii growth and pathogenesis.
    PLoS Pathog. 2023;19:e1011491.
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  98. BERNARD Q, Goumeidane M, Chaumond E, Robbe-Saule M, et al
    Type-I interferons promote innate immune tolerance in macrophages exposed to Mycobacterium ulcerans vesicles.
    PLoS Pathog. 2023;19:e1011479.
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  99. HOLMES CL, Wilcox AE, Forsyth V, Smith SN, et al
    Klebsiella pneumoniae causes bacteremia using factors that mediate tissue-specific fitness and resistance to oxidative stress.
    PLoS Pathog. 2023;19:e1011233.
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  100. BASKERVILLE MJ, Kovalyova Y, Mejias-Luque R, Gerhard M, et al
    Isotope tracing reveals bacterial catabolism of host-derived glutathione during Helicobacter pylori infection.
    PLoS Pathog. 2023;19:e1011526.
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  101. ZHU W, Passalia FJ, Hamond C, Abe CM, et al
    MPL36, a major plasminogen (PLG) receptor in pathogenic Leptospira, has an essential role during infection.
    PLoS Pathog. 2023;19:e1011313.
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  102. LONG GS, Hider J, Duggan AT, Klunk J, et al
    A 14th century CE Brucella melitensis genome and the recent expansion of the Western Mediterranean clade.
    PLoS Pathog. 2023;19:e1011538.
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  103. PARKER CE, Hiss AN, Spyrou MA, Neumann GU, et al
    14th century Yersinia pestis genomes support emergence of pestis secunda within Europe.
    PLoS Pathog. 2023;19:e1011404.
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    June 2023
  104. MERRIMAN JA, Xu W, Caparon MG
    Central carbon flux controls growth/damage balance for Streptococcus pyogenes.
    PLoS Pathog. 2023;19:e1011481.
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  105. WILDEMAN AS, Patel NK, Cormack BP, Culotta VC, et al
    The role of manganese in morphogenesis and pathogenesis of the opportunistic fungal pathogen Candida albicans.
    PLoS Pathog. 2023;19:e1011478.
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  106. MORRISON HM, Craft J, Rivera-Lugo R, Johnson JR, et al
    Deficiency in Galectin-3, -8, and -9 impairs immunity to chronic Mycobacterium tuberculosis infection but not acute infection with multiple intracellular pathogens.
    PLoS Pathog. 2023;19:e1011088.
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  107. WALSH SK, Imrie RM, Matuszewska M, Paterson GK, et al
    The host phylogeny determines viral infectivity and replication across Staphylococcus host species.
    PLoS Pathog. 2023;19:e1011433.
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  108. KIRSCH JM, Ely S, Stellfox ME, Hullahalli K, et al
    Targeted IS-element sequencing uncovers transposition dynamics during selective pressure in enterococci.
    PLoS Pathog. 2023;19:e1011424.
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  109. CANOVAS-MARQUEZ JT, Lax C, Tahiri G, Navarro E, et al
    Advances in understanding infections caused by the basal fungus Mucor.
    PLoS Pathog. 2023;19:e1011394.
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  110. DUBE JY, Behr MA
    A nod to the bond between NOD2 and mycobacteria.
    PLoS Pathog. 2023;19:e1011389.
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  111. TSUGAWA H, Ohki T, Tsubaki S, Tanaka R, et al
    Gas6 ameliorates intestinal mucosal immunosenescence to prevent the translocation of a gut pathobiont, Klebsiella pneumoniae, to the liver.
    PLoS Pathog. 2023;19:e1011139.
    >> Share

  112. POLLOCK TY, Vazquez Marrero VR, Brodsky IE, Shin S, et al
    TNF licenses macrophages to undergo rapid caspase-1, -11, and -8-mediated cell death that restricts Legionella pneumophila infection.
    PLoS Pathog. 2023;19:e1010767.
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  113. DISTEL JS, Di Venanzio G, Mackel JJ, Rosen DA, et al
    Replicative Acinetobacter baumannii strains interfere with phagosomal maturation by modulating the vacuolar pH.
    PLoS Pathog. 2023;19:e1011173.
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  114. NGWAGA T, Chauhan D, Salberg AG, Shames SR, et al
    Effector-mediated subversion of proteasome activator (PA)28alphabeta enhances host defense against Legionella pneumophila under inflammatory and oxidative stress conditions.
    PLoS Pathog. 2023;19:e1011473.
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  115. FURUTA A, Coleman M, Casares R, Seepersaud R, et al
    CD1 and iNKT cells mediate immune responses against the GBS hemolytic lipid toxin induced by a non-toxic analog.
    PLoS Pathog. 2023;19:e1011490.
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  116. GUL E, Enz U, Maurer L, Abi Younes A, et al
    Intraluminal neutrophils limit epithelium damage by reducing pathogen assault on intestinal epithelial cells during Salmonella gut infection.
    PLoS Pathog. 2023;19:e1011235.
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    May 2023
  117. NORAMBUENA J, Al-Tameemi H, Bovermann H, Kim J, et al
    Copper ions inhibit pentose phosphate pathway function in Staphylococcus aureus.
    PLoS Pathog. 2023;19:e1011393.
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  118. SCHOEN TJ, Calise DG, Bok JW, Giese MA, et al
    Aspergillus fumigatus transcription factor ZfpA regulates hyphal development and alters susceptibility to antifungals and neutrophil killing during infection.
    PLoS Pathog. 2023;19:e1011152.
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  119. OBAR JJ, Shepardson KM
    Coinfections in the lung: How viral infection creates a favorable environment for bacterial and fungal infections.
    PLoS Pathog. 2023;19:e1011334.
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  120. WANTUCH PL, Knoot CJ, Robinson LS, Vinogradov E, et al
    Capsular polysaccharide inhibits vaccine-induced O-antigen antibody binding and function across both classical and hypervirulent K2:O1 strains of Klebsiella pneumoniae.
    PLoS Pathog. 2023;19:e1011367.
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  121. PARMAR S, Tocheva EI
    The cell envelope of Mycobacterium abscessus and its role in pathogenesis.
    PLoS Pathog. 2023;19:e1011318.
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  122. NASKAR M, Parekh VP, Abraham MA, Alibasic Z, et al
    alpha-Hemolysin promotes uropathogenic E. coli persistence in bladder epithelial cells via abrogating bacteria-harboring lysosome acidification.
    PLoS Pathog. 2023;19:e1011388.
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  123. BLANC M, Lettl C, Guerin J, Vieille A, et al
    Designed Ankyrin Repeat Proteins provide insights into the structure and function of CagI and are potent inhibitors of CagA translocation by the Helicobacter pylori type IV secretion system.
    PLoS Pathog. 2023;19:e1011368.
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  124. VIANA F, Boucontet L, Laghi V, Schator D, et al
    Hiding in the yolk: A unique feature of Legionella pneumophila infection of zebrafish.
    PLoS Pathog. 2023;19:e1011375.
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  125. WAGNER R, Montoya L, Head JR, Campo S, et al
    Coccidioides undetected in soils from agricultural land and uncorrelated with time or the greater soil fungal community on undeveloped land.
    PLoS Pathog. 2023;19:e1011391.
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  126. MANCA B, Buffi G, Magri G, Del Vecchio M, et al
    Functional characterization of the gonococcal polyphosphate pseudo-capsule.
    PLoS Pathog. 2023;19:e1011400.
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  127. GLOVER RC, Schwardt NH, Leano SE, Sanchez ME, et al
    A genome-wide screen in macrophages identifies PTEN as required for myeloid restriction of Listeria monocytogenes infection.
    PLoS Pathog. 2023;19:e1011058.
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  128. ECHLIN H, Iverson A, Sardo U, Rosch JW, et al
    Airway proteolytic control of pneumococcal competence.
    PLoS Pathog. 2023;19:e1011421.
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    April 2023
  129. ZWYER M, Rutaihwa LK, Windels E, Hella J, et al
    Back-to-Africa introductions of Mycobacterium tuberculosis as the main cause of tuberculosis in Dar es Salaam, Tanzania.
    PLoS Pathog. 2023;19:e1010893.
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  130. AKINBOBOLA AB, Kean R, Hanifi SMA, Quilliam RS, et al
    Environmental reservoirs of the drug-resistant pathogenic yeast Candida auris.
    PLoS Pathog. 2023;19:e1011268.
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  131. VAILLANCOURT M, Galdino ACM, Limsuwannarot SP, Celedonio D, et al
    A compensatory RNase E variation increases Iron Piracy and Virulence in multidrug-resistant Pseudomonas aeruginosa during Macrophage infection.
    PLoS Pathog. 2023;19:e1010942.
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  132. JOHNSON AF, Sands JS, Trivedi KM, Russell R, et al
    Constitutive secretion of pro-IL-18 allows keratinocytes to initiate inflammation during bacterial infection.
    PLoS Pathog. 2023;19:e1011321.
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  133. JACOB JJ, Pragasam AK, Vasudevan K, Velmurugan A, et al
    Genomic analysis unveils genome degradation events and gene flux in the emergence and persistence of S. Paratyphi A lineages.
    PLoS Pathog. 2023;19:e1010650.
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  134. LEE HH, Carmichael DJ, Ribeiro V, Parisi DN, et al
    Glucuronoxylomannan intranasal challenge prior to Cryptococcus neoformans pulmonary infection enhances cerebral cryptococcosis in rodents.
    PLoS Pathog. 2023;19:e1010941.
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  135. PROBST C, Hallas-Moller M, Ipsen JO, Brooks JT, et al
    A fungal lytic polysaccharide monooxygenase is required for cell wall integrity, thermotolerance, and virulence of the fungal human pathogen Cryptococcus neoformans.
    PLoS Pathog. 2023;19:e1010946.
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    March 2023
  136. LEOPOLD WAGER CM, Bonifacio JR, Simper J, Naoun AA, et al
    Activation of transcription factor CREB in human macrophages by Mycobacterium tuberculosis promotes bacterial survival, reduces NF-kB nuclear transit and limits phagolysosome fusion by reduced necroptotic signaling.
    PLoS Pathog. 2023;19:e1011297.
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  137. BING J, Guan Z, Zheng T, Zhang Z, et al
    Clinical isolates of Candida auris with enhanced adherence and biofilm formation due to genomic amplification of ALS4.
    PLoS Pathog. 2023;19:e1011239.
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  138. CHEN Y, Bharrhan S, Xu J, Sharma T, et al
    B cells promote granulomatous inflammation during chronic Mycobacterium tuberculosis infection in mice.
    PLoS Pathog. 2023;19:e1011187.
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  139. BELHAOUANE I, Pochet A, Chatagnon J, Hoffmann E, et al
    Tirap controls Mycobacterium tuberculosis phagosomal acidification.
    PLoS Pathog. 2023;19:e1011192.
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  140. PAHUJA I, Negi K, Kumari A, Agarwal M, et al
    Berberine governs NOTCH3/AKT signaling to enrich lung-resident memory T cells during tuberculosis.
    PLoS Pathog. 2023;19:e1011165.
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  141. NIU K, Meng Y, Liu M, Ma Z, et al
    Phosphorylation of GntR reduces Streptococcus suis oxidative stress resistance and virulence by inhibiting NADH oxidase transcription.
    PLoS Pathog. 2023;19:e1011227.
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  142. WERNER LM, Alcott A, Mohlin F, Ray JC, et al
    Neisseria gonorrhoeae co-opts C4b-binding protein to enhance complement-independent survival from neutrophils.
    PLoS Pathog. 2023;19:e1011055.
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  143. SHARMA C, Kadosh D
    Perspective on the origin, resistance, and spread of the emerging human fungal pathogen Candida auris.
    PLoS Pathog. 2023;19:e1011190.
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  144. MOK C, Xiao MA, Wan YC, Zhao W, et al
    High-throughput phenotyping of infection by diverse microsporidia species reveals a wild C. elegans strain with opposing resistance and susceptibility traits.
    PLoS Pathog. 2023;19:e1011225.
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  145. MUGGEO A, Coraux C, Guillard T
    Current concepts on Pseudomonas aeruginosa interaction with human airway epithelium.
    PLoS Pathog. 2023;19:e1011221.
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  146. ISLAM EA, Fegan JE, Tefera TA, Curran DM, et al
    Reverse vaccinology-based identification of a novel surface lipoprotein that is an effective vaccine antigen against bovine infections caused by Pasteurella multocida.
    PLoS Pathog. 2023;19:e1011249.
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  147. ROMEIS E, Lieberman NAP, Molini B, Tantalo LC, et al
    Treponema pallidum subsp. pallidum with an Artificially impaired TprK antigenic variation system is attenuated in the Rabbit model of syphilis.
    PLoS Pathog. 2023;19:e1011259.
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  148. TOURE H, Galindo LA, Lagune M, Glatigny S, et al
    Mycobacterium abscessus resists the innate cellular response by surviving cell lysis of infected phagocytes.
    PLoS Pathog. 2023;19:e1011257.
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  149. DALLMANN-SAUER M, Xu YZ, da Costa ALF, Tao S, et al
    Allele-dependent interaction of LRRK2 and NOD2 in leprosy.
    PLoS Pathog. 2023;19:e1011260.
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    February 2023
  150. REUTER J, Otten C, Jacquier N, Lee J, et al
    An NlpC/P60 protein catalyzes a key step in peptidoglycan recycling at the intersection of energy recovery, cell division and immune evasion in the intracellular pathogen Chlamydia trachomatis.
    PLoS Pathog. 2023;19:e1011047.
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  151. LIYAYI IK, Forehand AL, Ray JC, Criss AK, et al
    Metal piracy by Neisseria gonorrhoeae to overcome human nutritional immunity.
    PLoS Pathog. 2023;19:e1011091.
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  152. KEOGH RA, Doran KS
    Group B Streptococcus and diabetes: Finding the sweet spot.
    PLoS Pathog. 2023;19:e1011133.
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  153. DEL POETA M, Wormley FL Jr, Lin X
    Host populations, challenges, and commercialization of cryptococcal vaccines.
    PLoS Pathog. 2023;19:e1011115.
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  154. MISSON P, Bruder E, Cornuault JK, De Paepe M, et al
    Phage production is blocked in the adherent-invasive Escherichia coli LF82 upon macrophage infection.
    PLoS Pathog. 2023;19:e1011127.
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  155. XING Y, Clark JR, Chang JD, Chirman DM, et al
    Broad protective vaccination against systemic Escherichia coli with autotransporter antigens.
    PLoS Pathog. 2023;19:e1011082.
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    The Cryptococcus wall: A different wall for a unique lifestyle.
    PLoS Pathog. 2023;19:e1011141.
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  157. FULLEN AR, Gutierrez-Ferman JL, Rayner RE, Kim SH, et al
    Architecture and matrix assembly determinants of Bordetella pertussis biofilms on primary human airway epithelium.
    PLoS Pathog. 2023;19:e1011193.
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  158. WANG DN, Ni JJ, Li JH, Gao YQ, et al
    Bacterial infection promotes tumorigenesis of colorectal cancer via regulating CDC42 acetylation.
    PLoS Pathog. 2023;19:e1011189.
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    January 2023
  159. CRAVENER MV, Do E, May G, Zarnowski R, et al
    Reinforcement amid genetic diversity in the Candida albicans biofilm regulatory network.
    PLoS Pathog. 2023;19:e1011109.
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  160. ZHAO C, Bao L, Zhao Y, Wu K, et al
    A fiber-enriched diet alleviates Staphylococcus aureus-induced mastitis by activating the HDAC3-mediated antimicrobial program in macrophages via butyrate production in mice.
    PLoS Pathog. 2023;19:e1011108.
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  161. LEHMAN MK, Sturd NA, Razvi F, Wellems DL, et al
    Proline transporters ProT and PutP are required for Staphylococcus aureus infection.
    PLoS Pathog. 2023;19:e1011098.
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  162. STEMPINSKI PR, Gerbig GR, Greengo SD, Casadevall A, et al
    Last but not yeast-The many forms of Cryptococcus neoformans.
    PLoS Pathog. 2023;19:e1011048.
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  163. JENKS JD, Aneke CI, Al-Obaidi MM, Egger M, et al
    Race and ethnicity: Risk factors for fungal infections?
    PLoS Pathog. 2023;19:e1011025.
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  164. MARSHALL A, McGrath JW, Graham R, McMullan G, et al
    Food for thought-The link between Clostridioides difficile metabolism and pathogenesis.
    PLoS Pathog. 2023;19:e1011034.
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  165. GLANVILLE DG, Gazioglu O, Marra M, Tokars VL, et al
    Pneumococcal capsule expression is controlled through a conserved, distal cis-regulatory element during infection.
    PLoS Pathog. 2023;19:e1011035.
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  166. SHI Y, Cao Q, Sun J, Hu X, et al
    The opportunistic pathogen Pseudomonas aeruginosa exploits bacterial biotin synthesis pathway to benefit its infectivity.
    PLoS Pathog. 2023;19:e1011110.
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    December 2022
  167. PLATT MP, Lin YH, Penix T, Wiscovitch-Russo R, et al
    A multiomics analysis of direct interkingdom dynamics between influenza A virus and Streptococcus pneumoniae uncovers host-independent changes to bacterial virulence fitness.
    PLoS Pathog. 2022;18:e1011020.
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  168. MITCHELL CL, Schwarzer AR, Miarinjara A, Jarrett CO, et al
    A Role for Early-Phase Transmission in the Enzootic Maintenance of Plague.
    PLoS Pathog. 2022;18:e1010996.
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  169. BOYER AE, Gallegos-Candela M, Lins RC, Solano MI, et al
    Comprehensive characterization of toxins during progression of inhalation anthrax in a non-human primate model.
    PLoS Pathog. 2022;18:e1010735.
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  170. SASTRE-VELASQUEZ LE, Dallemulle A, Kuhbacher A, Baldin C, et al
    The fungal expel of 5-fluorocytosine derived fluoropyrimidines mitigates its antifungal activity and generates a cytotoxic environment.
    PLoS Pathog. 2022;18:e1011066.
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  171. LAUKAITIS HJ, Cooper TT, Suwanbongkot C, Verhoeve VI, et al
    Transposon mutagenesis of Rickettsia felis sca1 confers a distinct phenotype during flea infection.
    PLoS Pathog. 2022;18:e1011045.
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  172. WORTEL IMN, Kim S, Liu AY, Ibarra EC, et al
    Listeria motility increases the efficiency of epithelial invasion during intestinal infection.
    PLoS Pathog. 2022;18:e1011028.
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    November 2022
  173. HURST JR, Shannon BA, Craig HC, Rishi A, et al
    The Streptococcus pyogenes hyaluronic acid capsule promotes experimental nasal and skin infection by preventing neutrophil-mediated clearance.
    PLoS Pathog. 2022;18:e1011013.
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  174. SANGER PA, Wagner S, Liebler-Tenorio E, Fuchs TM, et al
    Dissecting the invasion of Galleria mellonella by Yersinia enterocolitica reveals metabolic adaptations and a role of a phage lysis cassette in insect killing.
    PLoS Pathog. 2022;18:e1010991.
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  175. HERRING SE, Mao S, Bhalla M, Tchalla EYI, et al
    Mitochondrial ROS production by neutrophils is required for host antimicrobial function against Streptococcus pneumoniae and is controlled by A2B adenosine receptor signaling.
    PLoS Pathog. 2022;18:e1010700.
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  176. ZHANG Y, Wang Y, Fan J, Zhu G, et al
    Aspergillus fumigatus Elongator complex subunit 3 affects hyphal growth, adhesion and virulence through wobble uridine tRNA modification.
    PLoS Pathog. 2022;18:e1010976.
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  177. MO R, Ma W, Zhou W, Gao B, et al
    Polar localization of CheO under hypoxia promotes Campylobacter jejuni chemotactic behavior within host.
    PLoS Pathog. 2022;18:e1010953.
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    October 2022
  178. KUMAR R, Taylor JC, Jain A, Jung SY, et al
    Modulation of the extracellular matrix by Streptococcus gallolyticus subsp. gallolyticus and importance in cell proliferation.
    PLoS Pathog. 2022;18:e1010894.
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  179. SMITH C, Lee SC
    Current treatments against mucormycosis and future directions.
    PLoS Pathog. 2022;18:e1010858.
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  180. LAWRENCE AE, Berger RP, Hill DR, Huang S, et al
    Human neutrophil IL1beta directs intestinal epithelial cell extrusion during Salmonella infection.
    PLoS Pathog. 2022;18:e1010855.
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  181. LIU M, Wang Q, Wu W, Chen M, et al
    Glaesserella parasuis serotype 5 breaches the porcine respiratory epithelial barrier by inducing autophagy and blocking the cell membrane Claudin-1 replenishment.
    PLoS Pathog. 2022;18:e1010912.
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  182. HELBLE JD, McCarthy JE, Sawden M, Starnbach MN, et al
    The PD-1/PD-L1 pathway is induced during Borrelia burgdorferi infection and inhibits T cell joint infiltration without compromising bacterial clearance.
    PLoS Pathog. 2022;18:e1010903.
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    September 2022
  183. LIU J, Lai X, Yu R, Ding H, et al
    Progranulin aggravates lethal Candida albicans sepsis by regulating inflammatory response and antifungal immunity.
    PLoS Pathog. 2022;18:e1010873.
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  184. SPIEGELMAN L, Bahn-Suh A, Montano ET, Zhang L, et al
    Strengthening of enterococcal biofilms by Esp.
    PLoS Pathog. 2022;18:e1010829.
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  185. OUELLETTE SP, Fisher-Marvin LA, Harpring M, Lee J, et al
    Localized cardiolipin synthesis is required for the assembly of MreB during the polarized cell division of Chlamydia trachomatis.
    PLoS Pathog. 2022;18:e1010836.
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  186. CORTINA ME, Bishop RC, DeVasure BA, Coppens I, et al
    The inclusion membrane protein IncS is critical for initiation of the Chlamydia intracellular developmental cycle.
    PLoS Pathog. 2022;18:e1010818.
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  187. WONG JJ, Ho FK, Choo PY, Chong KKL, et al
    Escherichia coli BarA-UvrY regulates the pks island and kills Staphylococci via the genotoxin colibactin during interspecies competition.
    PLoS Pathog. 2022;18:e1010766.
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  188. EIX EF, Nett JE
    Modeling Candida auris skin colonization: Mice, swine, and humans.
    PLoS Pathog. 2022;18:e1010730.
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  189. SHELDON JR, Himmel LE, Kunkle DE, Monteith AJ, et al
    Lipocalin-2 is an essential component of the innate immune response to Acinetobacter baumannii infection.
    PLoS Pathog. 2022;18:e1010809.
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  190. CHOWDHARY A, Singh A, Kaur A, Khurana A, et al
    The emergence and worldwide spread of the species Trichophyton indotineae causing difficult-to-treat dermatophytosis: A new challenge in the management of dermatophytosis.
    PLoS Pathog. 2022;18:e1010795.
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  191. COHEN A, Jeng EE, Voorhies M, Symington J, et al
    Genome-scale CRISPR screening reveals that C3aR signaling is critical for rapid capture of fungi by macrophages.
    PLoS Pathog. 2022;18:e1010237.
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  192. GILCHRIST JJ, Auckland K, Parks T, Mentzer AJ, et al
    Genome-wide association study of leprosy in Malawi and Mali.
    PLoS Pathog. 2022;18:e1010312.
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    August 2022
  193. GANGULY T, Peterson AM, Burkholder M, Kajfasz JK, et al
    ZccE is a Novel P-type ATPase That Protects Streptococcus mutans Against Zinc Intoxication.
    PLoS Pathog. 2022;18:e1010477.
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  194. MENG Y, Wang Q, Ma Z, Li W, et al
    Streptococcal autolysin promotes dysfunction of swine tracheal epithelium by interacting with vimentin.
    PLoS Pathog. 2022;18:e1010765.
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  195. HUANG X, Li X, An H, Wang J, et al
    Capsule type defines the capability of Klebsiella pneumoniae in evading Kupffer cell capture in the liver.
    PLoS Pathog. 2022;18:e1010693.
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  196. CORCORAN JA, Napier BA
    C3aR plays both sides in regulating resistance to bacterial infections.
    PLoS Pathog. 2022;18:e1010657.
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  197. NEUPANE DP, Ahn C, Yang YA, Lee GY, et al
    Malnutrition and maternal vaccination against typhoid toxin.
    PLoS Pathog. 2022;18:e1010731.
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  198. SAIDYKHAN L, Correia J, Romanyuk A, Peacock AFA, et al
    An in vitro method for inducing titan cells reveals novel features of yeast-to-titan switching in the human fungal pathogen Cryptococcus gattii.
    PLoS Pathog. 2022;18:e1010321.
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  199. FULLEN AR, Gutierrez-Ferman JL, Yount KS, Love CF, et al
    Bps polysaccharide of Bordetella pertussis resists antimicrobial peptides by functioning as a dual surface shield and decoy and converts Escherichia coli into a respiratory pathogen.
    PLoS Pathog. 2022;18:e1010764.
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  200. JIANG M, Chen ZG, Li H, Zhang TT, et al
    Succinate and inosine coordinate innate immune response to bacterial infection.
    PLoS Pathog. 2022;18:e1010796.
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    July 2022
  201. GIBSON PS, Bexkens E, Zuber S, Cowley LA, et al
    The acquisition of clinically relevant amoxicillin resistance in Streptococcus pneumoniae requires ordered horizontal gene transfer of four loci.
    PLoS Pathog. 2022;18:e1010727.
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  202. VAN DIS E, Fox DM, Morrison HM, Fines DM, et al
    IFN-gamma-independent control of M. tuberculosis requires CD4 T cell-derived GM-CSF and activation of HIF-1alpha.
    PLoS Pathog. 2022;18:e1010721.
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  203. SULLIVAN MJ, Goh KGK, Ulett GC
    Regulatory cross-talk supports resistance to Zn intoxication in Streptococcus.
    PLoS Pathog. 2022;18:e1010607.
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  204. MARTINI MC, Hicks ND, Xiao J, Alonso MN, et al
    Loss of RNase J leads to multi-drug tolerance and accumulation of highly structured mRNA fragments in Mycobacterium tuberculosis.
    PLoS Pathog. 2022;18:e1010705.
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  205. KELLY AM, Leech JM, Doyle SL, McLoughlin RM, et al
    Staphylococcus aureus-induced immunosuppression mediated by IL-10 and IL-27 facilitates nasal colonisation.
    PLoS Pathog. 2022;18:e1010647.
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  206. FU M, Liu Y, Wang G, Wang P, et al
    A protein-protein interaction map reveals that the Coxiella burnetii effector CirB inhibits host proteasome activity.
    PLoS Pathog. 2022;18:e1010660.
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    Mycobacteriophages: From Petri dish to patient.
    PLoS Pathog. 2022;18:e1010602.
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    Fungal-mediated lung allergic airway disease: The critical role of macrophages and dendritic cells.
    PLoS Pathog. 2022;18:e1010608.
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  209. NICHOLSON KR, Champion PA
    Bacterial secretion systems: Networks of pathogenic regulation and adaptation in mycobacteria and beyond.
    PLoS Pathog. 2022;18:e1010610.
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  210. PHAN QT, Solis NV, Lin J, Swidergall M, et al
    Serum bridging molecules drive candidal invasion of human but not mouse endothelial cells.
    PLoS Pathog. 2022;18:e1010681.
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  211. OLANDER M, Sixt BS
    Bringing genetics to heretofore intractable obligate intracellular bacterial pathogens: Chlamydia and beyond.
    PLoS Pathog. 2022;18:e1010669.
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  212. DAVID S, Wong JLC, Sanchez-Garrido J, Kwong HS, et al
    Widespread emergence of OmpK36 loop 3 insertions among multidrug-resistant clones of Klebsiella pneumoniae.
    PLoS Pathog. 2022;18:e1010334.
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  213. DRAGOTAKES Q, Jacobs E, Ramirez LS, Yoon OI, et al
    Bet-hedging antimicrobial strategies in macrophage phagosome acidification drive the dynamics of Cryptococcus neoformans intracellular escape mechanisms.
    PLoS Pathog. 2022;18:e1010697.
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  214. PAN Z, He P, Zhang Y, Gu Q, et al
    SssP1, a Fimbria-like component of Streptococcus suis, binds to the vimentin of host cells and contributes to bacterial meningitis.
    PLoS Pathog. 2022;18:e1010710.
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    June 2022
  215. QI W, Acosta-Zaldivar M, Flanagan PR, Liu NN, et al
    Stress- and metabolic responses of Candida albicans require Tor1 kinase N-terminal HEAT repeats.
    PLoS Pathog. 2022;18:e1010089.
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  216. WU Z, Fan H, Jin J, Gao S, et al
    Insight into mechanisms of pig lncRNA FUT3-AS1 regulating E. coli F18-bacterial diarrhea.
    PLoS Pathog. 2022;18:e1010584.
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  217. FIGUEIREDO J, Henriques MX, Catalao MJ, Pinheiro S, et al
    Encapsulation of the septal cell wall protects Streptococcus pneumoniae from its major peptidoglycan hydrolase and host defenses.
    PLoS Pathog. 2022;18:e1010516.
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  218. KLIMOVA N, Holubova J, Streparola G, Tomala J, et al
    Pertussis toxin suppresses dendritic cell-mediated delivery of B. pertussis into lung-draining lymph nodes.
    PLoS Pathog. 2022;18:e1010577.
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  219. BORBORA SM, Rajmani RS, Balaji KN
    PRMT5 epigenetically regulates the E3 ubiquitin ligase ITCH to influence lipid accumulation during mycobacterial infection.
    PLoS Pathog. 2022;18:e1010095.
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  220. HANCOCK SJ, Lo AW, Ve T, Day CJ, et al
    Ucl fimbriae regulation and glycan receptor specificity contribute to gut colonisation by extra-intestinal pathogenic Escherichia coli.
    PLoS Pathog. 2022;18:e1010582.
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  221. SMITH DFQ, Casadevall A
    On the relationship between Pathogenic Potential and Infective Inoculum.
    PLoS Pathog. 2022;18:e1010484.
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  222. POTEMBERG G, Demars A, Barbieux E, Reboul A, et al
    Genome-wide analysis of Brucella melitensis genes required throughout intranasal infection in mice.
    PLoS Pathog. 2022;18:e1010621.
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  223. PALRASU M, Zaika E, Paulrasu K, Caspa Gokulan R, et al
    Helicobacter pylori pathogen inhibits cellular responses to oncogenic stress and apoptosis.
    PLoS Pathog. 2022;18:e1010628.
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  224. PROBST C, Garcia-Santamarina S, Brooks JT, Van Der Kloet I, et al
    Interactions between copper homeostasis and the fungal cell wall affect copper stress resistance.
    PLoS Pathog. 2022;18:e1010195.
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  225. AZIMOVA D, Herrera N, Duvenage L, Voorhies M, et al
    Cbp1, a fungal virulence factor under positive selection, forms an effector complex that drives macrophage lysis.
    PLoS Pathog. 2022;18:e1010417.
    >> Share

    May 2022
  226. LIU X, Guo C, Zhuang K, Chen W, et al
    A recyclable and light-triggered nanofibrous membrane against the emerging fungal pathogen Candida auris.
    PLoS Pathog. 2022;18:e1010534.
    >> Share

  227. SIEWERT LK, Dehio C, Pinschewer DD
    Adaptive immune defense prevents Bartonella persistence upon trans-placental transmission.
    PLoS Pathog. 2022;18:e1010489.
    >> Share

  228. VAN ALST AJ, Demey LM, DiRita VJ
    Vibrio cholerae requires oxidative respiration through the bd-I and cbb3 oxidases for intestinal proliferation.
    PLoS Pathog. 2022;18:e1010102.
    >> Share

  229. SILVA ML, Ca B, Osorio NS, Rodrigues PNS, et al
    Tuberculosis caused by Mycobacterium africanum: Knowns and unknowns.
    PLoS Pathog. 2022;18:e1010490.
    >> Share

  230. BLYTON MDJ, Pyne M, Young P, Chappell K, et al
    Koala retrovirus load and non-A subtypes are associated with secondary disease among wild northern koalas.
    PLoS Pathog. 2022;18:e1010513.
    >> Share

  231. COSTA FG, Horswill AR
    Overcoming pH defenses on the skin to establish infections.
    PLoS Pathog. 2022;18:e1010512.
    >> Share

  232. BYERLY CD, Mitra S, Patterson LL, Pittner NA, et al
    Ehrlichia SLiM ligand mimetic activates Hedgehog signaling to engage a BCL-2 anti-apoptotic cellular program.
    PLoS Pathog. 2022;18:e1010345.
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  233. HOVE P, Madesh S, Nair A, Jaworski D, et al
    Targeted mutagenesis in Anaplasma marginale to define virulence and vaccine development against bovine anaplasmosis.
    PLoS Pathog. 2022;18:e1010540.
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  234. TAN X, Lin YP, Pereira MJ, Castellanos M, et al
    VlsE, the nexus for antigenic variation of the Lyme disease spirochete, also mediates early bacterial attachment to the host microvasculature under shear force.
    PLoS Pathog. 2022;18:e1010511.
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    April 2022
  235. BARTSCH P, Kilian C, Hellmig M, Paust HJ, et al
    Th17 cell plasticity towards a T-bet-dependent Th1 phenotype is required for bacterial control in Staphylococcus aureus infection.
    PLoS Pathog. 2022;18:e1010430.
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  236. TRIPATHI A, Anand K, Das M, O'Niel RA, et al
    Mycobacterium tuberculosis requires SufT for Fe-S cluster maturation, metabolism, and survival in vivo.
    PLoS Pathog. 2022;18:e1010475.
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  237. LEMBERG C, Martinez de San Vicente K, Frois-Martins R, Altmeier S, et al
    Candida albicans commensalism in the oral mucosa is favoured by limited virulence and metabolic adaptation.
    PLoS Pathog. 2022;18:e1010012.
    >> Share

  238. DIAGNE AM, Pelletier A, Durmort C, Faure A, et al
    Identification of a two-component regulatory system involved in antimicrobial peptide resistance in Streptococcus pneumoniae.
    PLoS Pathog. 2022;18:e1010458.
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  239. DA SILVA RAG, Tay WH, Ho FK, Tanoto FR, et al
    Enterococcus faecalis alters endo-lysosomal trafficking to replicate and persist within mammalian cells.
    PLoS Pathog. 2022;18:e1010434.
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  240. SULTAN AS, Theofilou VI, Alfaifi A, Montelongo-Jauregui D, et al
    Is Candida albicans an opportunistic oncogenic pathogen?
    PLoS Pathog. 2022;18:e1010413.
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  241. HOLUBOVA J, Stanek O, Juhasz A, Hamidou Soumana I, et al
    The Fim and FhaB adhesins play a crucial role in nasal cavity infection and Bordetella pertussis transmission in a novel mouse catarrhal infection model.
    PLoS Pathog. 2022;18:e1010402.
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  242. JUNG BG, Samten B, Dean K, Wallace RJ Jr, et al
    Early IL-17A production helps establish Mycobacterium intracellulare infection in mice.
    PLoS Pathog. 2022;18:e1010454.
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  243. GIBSON JF, Bojarczuk A, Evans RJ, Kamuyango AA, et al
    Blood vessel occlusion by Cryptococcus neoformans is a mechanism for haemorrhagic dissemination of infection.
    PLoS Pathog. 2022;18:e1010389.
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    March 2022
  244. LAVIN RC, Tan S
    Spatial relationships of intra-lesion heterogeneity in Mycobacterium tuberculosis microenvironment, replication status, and drug efficacy.
    PLoS Pathog. 2022;18:e1010459.
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  245. ROSAS MEJIA O, Gloag ES, Li J, Ruane-Foster M, et al
    Mice infected with Mycobacterium tuberculosis are resistant to acute disease caused by secondary infection with SARS-CoV-2.
    PLoS Pathog. 2022;18:e1010093.
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  246. MANZER HS, Villarreal RI, Doran KS
    Targeting the BspC-vimentin interaction to develop anti-virulence therapies during Group B streptococcal meningitis.
    PLoS Pathog. 2022;18:e1010397.
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  247. KOGAN K, Haapasalo K, Kotila T, Moore R, et al
    Mechanism of Borrelia immune evasion by FhbA-related proteins.
    PLoS Pathog. 2022;18:e1010338.
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  248. THRIKAWALA S, Niu M, Keller NP, Rosowski EE, et al
    Cyclooxygenase production of PGE2 promotes phagocyte control of A. fumigatus hyphal growth in larval zebrafish.
    PLoS Pathog. 2022;18:e1010040.
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  249. PETERS DT, Reifs A, Alonso-Caballero A, Madkour A, et al
    Unraveling the molecular determinants of the anti-phagocytic protein cloak of plague bacteria.
    PLoS Pathog. 2022;18:e1010447.
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  250. ANDERSON MT, Himpsl SD, Mitchell LA, Kingsley LG, et al
    Identification of distinct capsule types associated with Serratia marcescens infection isolates.
    PLoS Pathog. 2022;18:e1010423.
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  251. LI J, Ma Y, Paquette JK, Richards AC, et al
    The Cdkn2a gene product p19 alternative reading frame (p19ARF) is a critical regulator of IFNbeta-mediated Lyme arthritis.
    PLoS Pathog. 2022;18:e1010365.
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  252. RICHARDS CL, Raffel SJ, Bontemps-Gallo S, Dulebohn DP, et al
    The arginine deaminase system plays distinct roles in Borrelia burgdorferi and Borrelia hermsii.
    PLoS Pathog. 2022;18:e1010370.
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  253. DRECKTRAH D, Hall LS, Crouse B, Schwarz B, et al
    The glycerol-3-phosphate dehydrogenases GpsA and GlpD constitute the oxidoreductive metabolic linchpin for Lyme disease spirochete host infectivity and persistence in the tick.
    PLoS Pathog. 2022;18:e1010385.
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  254. KHO ZY, Azad MAK, Han ML, Zhu Y, et al
    Correlative proteomics identify the key roles of stress tolerance strategies in Acinetobacter baumannii in response to polymyxin and human macrophages.
    PLoS Pathog. 2022;18:e1010308.
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    February 2022
  255. RIXON JA, Depew CE, McSorley SJ
    Th1 cells are dispensable for primary clearance of Chlamydia from the female reproductive tract of mice.
    PLoS Pathog. 2022;18:e1010333.
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  256. HORSTMANN N, Myers KS, Tran CN, Flores AR, et al
    CovS inactivation reduces CovR promoter binding at diverse virulence factor encoding genes in group A Streptococcus.
    PLoS Pathog. 2022;18:e1010341.
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  257. WILBURN KM, Montague CR, Qin B, Woods AK, et al
    Pharmacological and genetic activation of cAMP synthesis disrupts cholesterol utilization in Mycobacterium tuberculosis.
    PLoS Pathog. 2022;18:e1009862.
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  258. RAMIREZ-ZAVALA B, Kruger I, Dunker C, Jacobsen ID, et al
    The protein kinase Ire1 has a Hac1-independent essential role in iron uptake and virulence of Candida albicans.
    PLoS Pathog. 2022;18:e1010283.
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  259. TATARA AM, Gandhi RG, Mooney DJ, Nelson SB, et al
    Antiplatelet therapy for Staphylococcus aureus bacteremia: Will it stick?
    PLoS Pathog. 2022;18:e1010240.
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  260. CORDSMEIER A, Rinkel S, Jeninga M, Schulze-Luehrmann J, et al
    The Coxiella burnetii T4SS effector protein AnkG hijacks the 7SK small nuclear ribonucleoprotein complex for reprogramming host cell transcription.
    PLoS Pathog. 2022;18:e1010266.
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  261. KROKEN AR, Gajenthra Kumar N, Yahr TL, Smith BE, et al
    Exotoxin S secreted by internalized Pseudomonas aeruginosa delays lytic host cell death.
    PLoS Pathog. 2022;18:e1010306.
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  262. KOSEOGLU VK, Jones MK, Agaisse H
    The type 3 secretion effector IpgD promotes S. flexneri dissemination.
    PLoS Pathog. 2022;18:e1010324.
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  263. WEDDLE EA, Koseoglu VK, DeVasure BA, Agaisse HF, et al
    The type three secretion system effector protein IpgB1 promotes Shigella flexneri cell-to-cell spread through double-membrane vacuole escape.
    PLoS Pathog. 2022;18:e1010380.
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  264. SCHMIDINGER B, Petri K, Lettl C, Li H, et al
    Helicobacter pylori binds human Annexins via Lipopolysaccharide to interfere with Toll-like Receptor 4 signaling.
    PLoS Pathog. 2022;18:e1010326.
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  265. PERITORE-GALVE FC, Shupe JA, Cave RJ, Childress KO, et al
    Glucosyltransferase-dependent and independent effects of Clostridioides difficile toxins during infection.
    PLoS Pathog. 2022;18:e1010323.
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    January 2022
  266. YANG M, Solis NV, Marshall M, Garleb R, et al
    Control of beta-glucan exposure by the endo-1,3-glucanase Eng1 in Candida albicans modulates virulence.
    PLoS Pathog. 2022;18:e1010192.
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  267. NASEER N, Egan MS, Reyes Ruiz VM, Scott WP, et al
    Human NAIP/NLRC4 and NLRP3 inflammasomes detect Salmonella type III secretion system activities to restrict intracellular bacterial replication.
    PLoS Pathog. 2022;18:e1009718.
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  268. TRAN TT, Mathmann CD, Gatica-Andrades M, Rollo RF, et al
    Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance from spacious replication vacuoles in infected macrophages.
    PLoS Pathog. 2022;18:e1010166.
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  269. JOHN E, Jacques S, Phan HTT, Liu L, et al
    Variability in an effector gene promoter of a necrotrophic fungal pathogen dictates epistasis and effector-triggered susceptibility in wheat.
    PLoS Pathog. 2022;18:e1010149.
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  270. HOSMER J, Nasreen M, Dhouib R, Essilfie AT, et al
    Access to highly specialized growth substrates and production of epithelial immunomodulatory metabolites determine survival of Haemophilus influenzae in human airway epithelial cells.
    PLoS Pathog. 2022;18:e1010209.
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  271. HERNANDEZ SB, Castanheira S, Pucciarelli MG, Cestero JJ, et al
    Peptidoglycan editing in non-proliferating intracellular Salmonella as source of interference with immune signaling.
    PLoS Pathog. 2022;18:e1010241.
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  272. ZHAO BR, Wang XX, Wang XW
    Shoc2 recognizes bacterial flagellin and mediates antibacterial Erk/Stat signaling in an invertebrate.
    PLoS Pathog. 2022;18:e1010253.
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  273. NEGRON O, Hur WS, Prasad J, Paul DS, et al
    Fibrin(ogen) engagement of S. aureus promotes the host antimicrobial response and suppression of microbe dissemination following peritoneal infection.
    PLoS Pathog. 2022;18:e1010227.
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  274. HSIEH LT, Dos Santos SJ, Hall BS, Ogbechi J, et al
    Aberrant stromal tissue factor localisation and mycolactone-driven vascular dysfunction, exacerbated by IL-1beta, are linked to fibrin formation in Buruli ulcer lesions.
    PLoS Pathog. 2022;18:e1010280.
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    December 2021
  275. REITHOFER V, Fernandez-Pereira J, Alvarado M, de Groot P, et al
    A novel class of Candida glabrata cell wall proteins with beta-helix fold mediates adhesion in clinical isolates.
    PLoS Pathog. 2021;17:e1009980.
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  276. SPENCER BL, Tak U, Mendonca JC, Nagao PE, et al
    A type VII secretion system in Group B Streptococcus mediates cytotoxicity and virulence.
    PLoS Pathog. 2021;17:e1010121.
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  277. MA Q, Pan Y, Chen Y, Yu S, et al
    Acetylation of glucosyltransferases regulates Streptococcus mutans biofilm formation and virulence.
    PLoS Pathog. 2021;17:e1010134.
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  278. CARROLL KC, Burnham CD, Westblade LF
    From canines to humans: Clinical importance of Staphylococcus pseudintermedius.
    PLoS Pathog. 2021;17:e1009961.
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  279. OLBRICH L, Stockdale L, Basu Roy R, Song R, et al
    Understanding the interaction between cytomegalovirus and tuberculosis in children: The way forward.
    PLoS Pathog. 2021;17:e1010061.
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  280. HURST JR, Brouwer S, Walker MJ, McCormick JK, et al
    Streptococcal superantigens and the return of scarlet fever.
    PLoS Pathog. 2021;17:e1010097.
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  281. IVANOV SS, Castore R, Juarez Rodriguez MD, Circu M, et al
    Neisseria gonorrhoeae subverts formin-dependent actin polymerization to colonize human macrophages.
    PLoS Pathog. 2021;17:e1010184.
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  282. ELDRIDGE MJG, Hamon MA
    Histone H3 deacetylation promotes host cell viability for efficient infection by Listeria monocytogenes.
    PLoS Pathog. 2021;17:e1010173.
    >> Share

  283. CHEN K, Zhang S, Shao Y, Guo M, et al
    A unique NLRC4 receptor from echinoderms mediates Vibrio phagocytosis via rearrangement of the cytoskeleton and polymerization of F-actin.
    PLoS Pathog. 2021;17:e1010145.
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  284. ROY S, Bahar AA, Gu H, Nangia S, et al
    Persister control by leveraging dormancy associated reduction of antibiotic efflux.
    PLoS Pathog. 2021;17:e1010144.
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  285. BASTOS RW, Rossato L, Goldman GH, Santos DA, et al
    Fungicide effects on human fungal pathogens: Cross-resistance to medical drugs and beyond.
    PLoS Pathog. 2021;17:e1010073.
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  286. CHU TH, Khairallah C, Shieh J, Cho R, et al
    gammadelta T cell IFNgamma production is directly subverted by Yersinia pseudotuberculosis outer protein YopJ in mice and humans.
    PLoS Pathog. 2021;17:e1010103.
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  287. GRASSMANN AA, Zavala-Alvarado C, Bettin EB, Picardeau M, et al
    The FUR-like regulators PerRA and PerRB integrate a complex regulatory network that promotes mammalian host-adaptation and virulence of Leptospira interrogans.
    PLoS Pathog. 2021;17:e1009078.
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  288. ZAVALA-ALVARADO C, G Huete S, Vincent AT, Sismeiro O, et al
    The oxidative stress response of pathogenic Leptospira is controlled by two peroxide stress regulators which putatively cooperate in controlling virulence.
    PLoS Pathog. 2021;17:e1009087.
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  289. YU Q, Wang LC, Di Benigno S, Stein DC, et al
    Gonococcal invasion into epithelial cells depends on both cell polarity and ezrin.
    PLoS Pathog. 2021;17:e1009592.
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    November 2021
  290. PAYROS D, Alonso H, Malaga W, Volle A, et al
    Rv0180c contributes to Mycobacterium tuberculosis cell shape and to infectivity in mice and macrophages.
    PLoS Pathog. 2021;17:e1010020.
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  291. VAN TONDER AJ, Thornton MJ, Conlan AJK, Jolley KA, et al
    Inferring Mycobacterium bovis transmission between cattle and badgers using isolates from the Randomised Badger Culling Trial.
    PLoS Pathog. 2021;17:e1010075.
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  292. BEKERE I, Huang J, Schnapp M, Rudolph M, et al
    Yersinia remodels epigenetic histone modifications in human macrophages.
    PLoS Pathog. 2021;17:e1010074.
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  293. PIENKOSS S, Javadi S, Chaoprasid P, Nolte T, et al
    The gatekeeper of Yersinia type III secretion is under RNA thermometer control.
    PLoS Pathog. 2021;17:e1009650.
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  294. DOORDUIJN DJ, Heesterbeek DAC, Ruyken M, de Haas CJC, et al
    Polymerization of C9 enhances bacterial cell envelope damage and killing by membrane attack complex pores.
    PLoS Pathog. 2021;17:e1010051.
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    October 2021
  295. PEKMEZOVIC M, Kaune AK, Austermeier S, Hitzler SUJ, et al
    Human albumin enhances the pathogenic potential of Candida glabrata on vaginal epithelial cells.
    PLoS Pathog. 2021;17:e1010037.
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  296. Correction: Correction: Glutamate dehydrogenase (Gdh2)-dependent alkalization is dispensable for escape from macrophages and virulence of Candida albicans.
    PLoS Pathog. 2021;17:e1010008.
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  297. LEAL-CALVO T, Avanzi C, Mendes MA, Benjak A, et al
    A new paradigm for leprosy diagnosis based on host gene expression.
    PLoS Pathog. 2021;17:e1009972.
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  298. PERES NG, Wang N, Whitney P, Engel S, et al
    CD4+ T cell immunity to Salmonella is transient in the circulation.
    PLoS Pathog. 2021;17:e1010004.
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  299. GREGORY AL, Pensinger DA, Hryckowian AJ
    A short chain fatty acid-centric view of Clostridioides difficile pathogenesis.
    PLoS Pathog. 2021;17:e1009959.
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  300. COBURN J, Picardeau M, Woods CW, Veldman T, et al
    Pathogenesis insights from an ancient and ubiquitous spirochete.
    PLoS Pathog. 2021;17:e1009836.
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  301. OUTRAM MA, Solomon PS, Williams SJ
    Pro-domain processing of fungal effector proteins from plant pathogens.
    PLoS Pathog. 2021;17:e1010000.
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  302. ABUAITA BH, Lawrence AE, Berger RP, Hill DR, et al
    Comparative transcriptional profiling of the early host response to infection by typhoidal and non-typhoidal Salmonella serovars in human intestinal organoids.
    PLoS Pathog. 2021;17:e1009987.
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  303. AGUIRRE AM, Yalcinkaya N, Wu Q, Swennes A, et al
    Bile acid-independent protection against Clostridioides difficile infection.
    PLoS Pathog. 2021;17:e1010015.
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  304. EARLE SG, Lobanovska M, Lavender H, Tang C, et al
    Genome-wide association studies reveal the role of polymorphisms affecting factor H binding protein expression in host invasion by Neisseria meningitidis.
    PLoS Pathog. 2021;17:e1009992.
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  305. GU H, Cai X, Zhang X, Luo J, et al
    A previously uncharacterized two-component signaling system in uropathogenic Escherichia coli coordinates protection against host-derived oxidative stress with activation of hemolysin-mediated host cell pyroptosis.
    PLoS Pathog. 2021;17:e1010005.
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  306. BLAND DM, Miarinjara A, Bosio CF, Calarco J, et al
    Acquisition of yersinia murine toxin enabled Yersinia pestis to expand the range of mammalian hosts that sustain flea-borne plague.
    PLoS Pathog. 2021;17:e1009995.
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  307. BJANES E, Sillas RG, Matsuda R, Demarco B, et al
    Genetic targeting of Card19 is linked to disrupted NINJ1 expression, impaired cell lysis, and increased susceptibility to Yersinia infection.
    PLoS Pathog. 2021;17:e1009967.
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  308. SULLIVAN JR, Lupien A, Kalthoff E, Hamela C, et al
    Efficacy of epetraborole against Mycobacterium abscessus is increased with norvaline.
    PLoS Pathog. 2021;17:e1009965.
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  309. KELLIHER JL, Grunenwald CM, Abrahams RR, Daanen ME, et al
    PASTA kinase-dependent control of peptidoglycan synthesis via ReoM is required for cell wall stress responses, cytosolic survival, and virulence in Listeria monocytogenes.
    PLoS Pathog. 2021;17:e1009881.
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    September 2021
  310. DE LAY BD, Cameron TA, De Lay NR, Norris SJ, et al
    Comparison of transcriptional profiles of Treponema pallidum during experimental infection of rabbits and in vitro culture: Highly similar, yet different.
    PLoS Pathog. 2021;17:e1009949.
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  311. GUTIERREZ S, Fischer J, Ganesan R, Hos NJ, et al
    Salmonella Typhimurium impairs glycolysis-mediated acidification of phagosomes to evade macrophage defense.
    PLoS Pathog. 2021;17:e1009943.
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  312. MCDOUGAL CE, Morrow ZT, Christopher T, Kim S, et al
    Phagocytes produce prostaglandin E2 in response to cytosolic Listeria monocytogenes.
    PLoS Pathog. 2021;17:e1009493.
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  313. GOLDSMITH JA, DiVenere AM, Maynard JA, McLellan JS, et al
    Structural basis for antibody binding to adenylate cyclase toxin reveals RTX linkers as neutralization-sensitive epitopes.
    PLoS Pathog. 2021;17:e1009920.
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  314. WU X, Ning C, Key FM, Andrades Valtuena A, et al
    A 3,000-year-old, basal S. enterica lineage from Bronze Age Xinjiang suggests spread along the Proto-Silk Road.
    PLoS Pathog. 2021;17:e1009886.
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  315. DEMARS A, Vitali A, Comein A, Carlier E, et al
    Aconitate decarboxylase 1 participates in the control of pulmonary Brucella infection in mice.
    PLoS Pathog. 2021;17:e1009887.
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  316. BAGAYOKO S, Leon-Icaza SA, Pinilla M, Hessel A, et al
    Host phospholipid peroxidation fuels ExoU-dependent cell necrosis and supports Pseudomonas aeruginosa-driven pathology.
    PLoS Pathog. 2021;17:e1009927.
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  317. RUSSO BC, Duncan-Lowey JK, Chen P, Goldberg MB, et al
    The type 3 secretion system requires actin polymerization to open translocon pores.
    PLoS Pathog. 2021;17:e1009932.
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  318. CULYBA MJ, Van Tyne D
    Bacterial evolution during human infection: Adapt and live or adapt and die.
    PLoS Pathog. 2021;17:e1009872.
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  319. TAGGART MG, Snelling WJ, Naughton PJ, La Ragione RM, et al
    Biofilm regulation in Clostridioides difficile: Novel systems linked to hypervirulence.
    PLoS Pathog. 2021;17:e1009817.
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  320. GUO Z, Kang S, Wu Q, Wang S, et al
    The regulation landscape of MAPK signaling cascade for thwarting Bacillus thuringiensis infection in an insect host.
    PLoS Pathog. 2021;17:e1009917.
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  321. XIA Y, Cebrian R, Xu C, Jong A, et al
    Elucidating the mechanism by which synthetic helper peptides sensitize Pseudomonas aeruginosa to multiple antibiotics.
    PLoS Pathog. 2021;17:e1009909.
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  322. VAIL KJ, da Silveira BP, Bell SL, Cohen ND, et al
    The opportunistic intracellular bacterial pathogen Rhodococcus equi elicits type I interferon by engaging cytosolic DNA sensing in macrophages.
    PLoS Pathog. 2021;17:e1009888.
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    August 2021
  323. POWERS TR, Haeberle AL, Predeus AV, Hammarlof DL, et al
    Intracellular niche-specific profiling reveals transcriptional adaptations required for the cytosolic lifestyle of Salmonella enterica.
    PLoS Pathog. 2021;17:e1009280.
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  324. DAVIDSON A, Tyler J, Hume P, Singh V, et al
    A kinase-independent function of PAK is crucial for pathogen-mediated actin remodelling.
    PLoS Pathog. 2021;17:e1009902.
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  325. BARBOSA CHD, Lantier L, Reynolds J, Wang J, et al
    Critical role of IL-25-ILC2-IL-5 axis in the production of anti-Francisella LPS IgM by B1 B cells.
    PLoS Pathog. 2021;17:e1009905.
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  326. HANSON MA, Cohen LB, Marra A, Iatsenko I, et al
    The Drosophila Baramicin polypeptide gene protects against fungal infection.
    PLoS Pathog. 2021;17:e1009846.
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  327. KUHN HW, Lasseter AG, Adams PP, Avile CF, et al
    BB0562 is a nutritional virulence determinant with lipase activity important for Borrelia burgdorferi infection and survival in fatty acid deficient environments.
    PLoS Pathog. 2021;17:e1009869.
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  328. ANAYA-SANCHEZ A, Feng Y, Berude JC, Portnoy DA, et al
    Detoxification of methylglyoxal by the glyoxalase system is required for glutathione availability and virulence activation in Listeria monocytogenes.
    PLoS Pathog. 2021;17:e1009819.
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  329. HALSEY CR, Glover RC, Thomason MK, Reniere ML, et al
    The redox-responsive transcriptional regulator Rex represses fermentative metabolism and is required for Listeria monocytogenes pathogenesis.
    PLoS Pathog. 2021;17:e1009379.
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  330. ZHANG HB, Cao Z, Qiao JX, Zhong ZQ, et al
    Metabolomics provide new insights into mechanisms of Wolbachia-induced paternal defects in Drosophila melanogaster.
    PLoS Pathog. 2021;17:e1009859.
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  331. GONG Y, Wei X, Sun W, Ren X, et al
    Exosomal miR-224 contributes to hemolymph microbiota homeostasis during bacterial infection in crustacean.
    PLoS Pathog. 2021;17:e1009837.
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  332. SYCZ G, Di Venanzio G, Distel JS, Sartorio MG, et al
    Modern Acinetobacter baumannii clinical isolates replicate inside spacious vacuoles and egress from macrophages.
    PLoS Pathog. 2021;17:e1009802.
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  333. GRAEF FA, Celiberto LS, Allaire JM, Kuan MTY, et al
    Fasting increases microbiome-based colonization resistance and reduces host inflammatory responses during an enteric bacterial infection.
    PLoS Pathog. 2021;17:e1009719.
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  334. MA L, Dewan KK, Taylor-Mulneix DL, Wagner SM, et al
    Pertactin contributes to shedding and transmission of Bordetella bronchiseptica.
    PLoS Pathog. 2021;17:e1009735.
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  335. RYTTER H, Jamet A, Ziveri J, Ramond E, et al
    The pentose phosphate pathway constitutes a major metabolic hub in pathogenic Francisella.
    PLoS Pathog. 2021;17:e1009326.
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  336. CUI J, Duizer C, Bouwman LI, van Rooijen KS, et al
    The ALPK1 pathway drives the inflammatory response to Campylobacter jejuni in human intestinal epithelial cells.
    PLoS Pathog. 2021;17:e1009787.
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    July 2021
  337. SCHERER AK, Hopke A, Sykes DB, Irimia D, et al
    Host defense against fungal pathogens: Adaptable neutrophil responses and the promise of therapeutic opportunities?
    PLoS Pathog. 2021;17:e1009691.
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  338. MEAGHER RB, Lewis ZA, Ambati S, Lin X, et al
    Aiming for a bull's-eye: Targeting antifungals to fungi with dectin-decorated liposomes.
    PLoS Pathog. 2021;17:e1009699.
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  339. BOURGEOIS JS, Wang L, Rabino AF, Everitt J, et al
    ARHGEF26 enhances Salmonella invasion and inflammation in cells and mice.
    PLoS Pathog. 2021;17:e1009713.
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  340. CERNY O, Godlee C, Tocci R, Cross NE, et al
    CD97 stabilises the immunological synapse between dendritic cells and T cells and is targeted for degradation by the Salmonella effector SteD.
    PLoS Pathog. 2021;17:e1009771.
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  341. GROSHONG AM, Grassmann AA, Luthra A, McLain MA, et al
    PlzA is a bifunctional c-di-GMP biosensor that promotes tick and mammalian host-adaptation of Borrelia burgdorferi.
    PLoS Pathog. 2021;17:e1009725.
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  342. CRUZ-MIRELES N, Eseola AB, Oses-Ruiz M, Ryder LS, et al
    From appressorium to transpressorium-Defining the morphogenetic basis of host cell invasion by the rice blast fungus.
    PLoS Pathog. 2021;17:e1009779.
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  343. BURKS C, Darby A, Gomez Londono L, Momany M, et al
    Azole-resistant Aspergillus fumigatus in the environment: Identifying key reservoirs and hotspots of antifungal resistance.
    PLoS Pathog. 2021;17:e1009711.
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  344. HART TM, Dupuis AP 2nd, Tufts DM, Blom AM, et al
    Host tropism determination by convergent evolution of immunological evasion in the Lyme disease system.
    PLoS Pathog. 2021;17:e1009801.
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  345. FISHER J, Card G, Liang Y, Trent B, et al
    Orientia tsutsugamushi selectively stimulates the C-type lectin receptor Mincle and type 1-skewed proinflammatory immune responses.
    PLoS Pathog. 2021;17:e1009782.
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  346. ZHAO C, Hu X, Bao L, Wu K, et al
    Aryl hydrocarbon receptor activation by Lactobacillus reuteri tryptophan metabolism alleviates Escherichia coli-induced mastitis in mice.
    PLoS Pathog. 2021;17:e1009774.
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  347. ALONSO-MONGE R, Gresnigt MS, Roman E, Hube B, et al
    Candida albicans colonization of the gastrointestinal tract: A double-edged sword.
    PLoS Pathog. 2021;17:e1009710.
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  348. MA Y, Yang X, Wang H, Qin Z, et al
    CBS-derived H2S facilitates host colonization of Vibrio cholerae by promoting the iron-dependent catalase activity of KatB.
    PLoS Pathog. 2021;17:e1009763.
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  349. GRIGORYEVA LS, Cianciotto NP
    Human macrophages utilize a wide range of pathogen recognition receptors to recognize Legionella pneumophila, including Toll-Like Receptor 4 engaging Legionella lipopolysaccharide and the Toll-like Receptor 3 nucleic-acid sensor.
    PLoS Pathog. 2021;17:e1009781.
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  350. FANG K, Zhou J, Chen L, Li YX, et al
    Virulence and community dynamics of fungal species with vertical and horizontal transmission on a plant with multiple infections.
    PLoS Pathog. 2021;17:e1009769.
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  351. KARO-ATAR D, Khan N, Divangahi M, King IL, et al
    Helminth-mediated disease tolerance in TB: A role for microbiota?
    PLoS Pathog. 2021;17:e1009690.
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  352. GANTHER S, Radaic A, Malone E, Kamarajan P, et al
    Treponema denticola dentilisin triggered TLR2/MyD88 activation upregulates a tissue destructive program involving MMPs via Sp1 in human oral cells.
    PLoS Pathog. 2021;17:e1009311.
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  353. DEMIROZ D, Platanitis E, Bryant M, Fischer P, et al
    Listeria monocytogenes infection rewires host metabolism with regulatory input from type I interferons.
    PLoS Pathog. 2021;17:e1009697.
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  354. BLACK B, Lee C, Horianopoulos LC, Jung WH, et al
    Respiring to infect: Emerging links between mitochondria, the electron transport chain, and fungal pathogenesis.
    PLoS Pathog. 2021;17:e1009661.
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  355. PATEL P, O'Hara BJ, Aunins E, Davis KM, et al
    Modifying TIMER to generate a slow-folding DsRed derivative for optimal use in quickly-dividing bacteria.
    PLoS Pathog. 2021;17:e1009284.
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    June 2021
  356. HWANG W, Yong JH, Min KB, Lee KM, et al
    Genome-wide association study of signature genetic alterations among pseudomonas aeruginosa cystic fibrosis isolates.
    PLoS Pathog. 2021;17:e1009681.
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  357. SANDS NA, Beernink PT
    Two human antibodies to a meningococcal serogroup B vaccine antigen enhance binding of complement Factor H by stabilizing the Factor H binding site.
    PLoS Pathog. 2021;17:e1009655.
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    May 2021
  358. STEINER SE, Choong FX, Antypas H, Morado-Urbina CE, et al
    UPEC kidney infection triggers neuro-immune communication leading to modulation of local renal inflammation by splenic IFNgamma.
    PLoS Pathog. 2021;17:e1009553.
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  359. DAVIS MM, Brock AM, DeHart TG, Boribong BP, et al
    The peptidoglycan-associated protein NapA plays an important role in the envelope integrity and in the pathogenesis of the lyme disease spirochete.
    PLoS Pathog. 2021;17:e1009546.
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  360. CHAU NYE, Ahmad S, Whitney JC, Coombes BK, et al
    Emerging and divergent roles of pyrophosphorylated nucleotides in bacterial physiology and pathogenesis.
    PLoS Pathog. 2021;17:e1009532.
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  361. STEVENS EJ, Bates KA, King KC
    Host microbiota can facilitate pathogen infection.
    PLoS Pathog. 2021;17:e1009514.
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  362. WALKER AC, Bhargava R, Vaziriyan-Sani AS, Pourciau C, et al
    Colonization of the Caenorhabditis elegans gut with human enteric bacterial pathogens leads to proteostasis disruption that is rescued by butyrate.
    PLoS Pathog. 2021;17:e1009510.
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  363. HUI WW, Emerson LE, Clapp B, Sheppe AE, et al
    Antigen-encapsulating host extracellular vesicles derived from Salmonella-infected cells stimulate pathogen-specific Th1-type responses in vivo.
    PLoS Pathog. 2021;17:e1009465.
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  364. LIN T, Quellier D, Lamb J, Voisin T, et al
    Pseudomonas aeruginosa-induced nociceptor activation increases susceptibility to infection.
    PLoS Pathog. 2021;17:e1009557.
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  365. PEREZ-MORALES D, Nava-Galeana J, Rosales-Reyes R, Teehan P, et al
    An incoherent feedforward loop formed by SirA/BarA, HilE and HilD is involved in controlling the growth cost of virulence factor expression by Salmonella Typhimurium.
    PLoS Pathog. 2021;17:e1009630.
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  366. PHENN J, Pane-Farre J, Meukow N, Klein A, et al
    RegAB Homolog of Burkholderia pseudomallei is the Master Regulator of Redox Control and involved in Virulence.
    PLoS Pathog. 2021;17:e1009604.
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  367. BESSAIAH H, Pokharel P, Loucif H, Kulbay M, et al
    The RyfA small RNA regulates oxidative and osmotic stress responses and virulence in uropathogenic Escherichia coli.
    PLoS Pathog. 2021;17:e1009617.
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  368. LIU C, Stocke K, Fitzsimonds ZR, Yakoumatos L, et al
    A bacterial tyrosine phosphatase modulates cell proliferation through targeting RGCC.
    PLoS Pathog. 2021;17:e1009598.
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  369. YEBRA G, Haag AF, Neamah MM, Wee BA, et al
    Radical genome remodelling accompanied the emergence of a novel host-restricted bacterial pathogen.
    PLoS Pathog. 2021;17:e1009606.
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  370. RETCHLESS AC, Chen A, Chang HY, Blain AE, et al
    Using Neisseria meningitidis genomic diversity to inform outbreak strain identification.
    PLoS Pathog. 2021;17:e1009586.
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  371. GOMES MTR, Guimaraes ES, Marinho FV, Macedo I, et al
    STING regulates metabolic reprogramming in macrophages via HIF-1alpha during Brucella infection.
    PLoS Pathog. 2021;17:e1009597.
    >> Share

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