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Irritable Bowel Syndrome
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Articles published in
Am J Gastroenterol
    June 2026
  1. BLOMSTEN A, Trindade IA, Nybacka S, Melchior C, et al
    Avoidant/Restrictive Eating in People With and Without Bowel Symptoms in the General Population: Prevalence, Clinical Profile, and Associated Factors.
    Am J Gastroenterol. 2026;121:1473-1483.
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    May 2026
  2. LEMBO AJ, Chey WD, Harris LA, Frazier R, et al
    Correction to: Abdominal Symptom Improvement During Clinical Trials of Tenapanor in Patients With Irritable Bowel Syndrome With Constipation: A Post Hoc Analysis.
    Am J Gastroenterol. 2026 May 4. doi: 10.14309/ajg.0000000000004025.
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    April 2026
  3. LOESCH J, Kim S, Simons M, Hamza E, et al
    Associations between Physical Activity and Irritable Bowel Syndrome in the All of Us Research Program.
    Am J Gastroenterol. 2026 Apr 27. doi: 10.14309/ajg.0000000000004037.
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    March 2026
  4. BERRY SK, Varma S, Basnayake C, Ahn JC, et al
    Virtual Multidisciplinary GI Care Clinic Improves Patient Engagement, Satisfaction, and Outcomes at Reduced Costs and Healthcare Utilization: A Prospective Cohort Study.
    Am J Gastroenterol. 2026 Mar 20. doi: 10.14309/ajg.0000000000004002.
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  5. COLECCHIA L, Marasco G, Capelli C, Facciorusso A, et al
    Antibiotic use during gastrointestinal infections increases the risk of developing irritable bowel syndrome: a Systematic Review and Meta-Analysis.
    Am J Gastroenterol. 2026 Mar 20. doi: 10.14309/ajg.0000000000004001.
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  6. COLOMIER E, Jones MP, Holvoet L, Van den Houte K, et al
    symptom patterns outside the rome iv consensus in eastern and western patients with a disorder of gut-brain interaction.
    Am J Gastroenterol. 2026 Mar 17. doi: 10.14309/ajg.0000000000003996.
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  7. BYALE A, Palsson OS, Simren M, Tack J, et al
    Bloating and Distention Patients Form 6 Distinct Latent Clusters Based on Symptoms, Diet, Psychosocial, and Quality-of-Life Parameters.
    Am J Gastroenterol. 2026;121:754-766.
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    February 2026
  8. BUSAM JA, Batta N, Rezaie A, Pimentel M, et al
    A systematic review of efficacy in irritable bowel syndrome: How the number needed to treat may be a misleading metric.
    Am J Gastroenterol. 2026 Feb 18. doi: 10.14309/ajg.0000000000003968.
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  9. LACY BE, Cangemi DJ, Brenner D
    Bloating and breath tests: A pragmatic approach.
    Am J Gastroenterol. 2026 Feb 13. doi: 10.14309/ajg.0000000000003963.
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  10. MIKHAEL-MOUSSA H, Desprez C, Gillibert A, Leroi AM, et al
    Is Carbohydrate Intolerance Associated With Carbohydrate Malabsorption in Disorders of Gut-Brain Interaction?
    Am J Gastroenterol. 2026;121:461-471.
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    November 2025
  11. GUTIERREZ-TORRES DS, Li F, Liao LM, Daniel CR, et al
    The Time-Dependent Association Between Irritable Bowel Syndrome and All-Cause and Cause-Specific Mortality in the NIH-AARP Cohort Study.
    Am J Gastroenterol. 2025 Nov 21. doi: 10.14309/ajg.0000000000003861.
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  12. SHIN A, Staller K, Levinthal DJ
    Actionable Clinical Features and Biomarkers to Facilitate the Management of Irritable Bowel Syndrome.
    Am J Gastroenterol. 2025 Nov 19. doi: 10.14309/ajg.0000000000003859.
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  13. ZHANG M, Wellens J, Zhao J, Ji H, et al
    Psychological Resilience and Mental Wellbeing Mitigate the Risk of Irritable Bowel Syndrome.
    Am J Gastroenterol. 2025 Nov 19. doi: 10.14309/ajg.0000000000003833.
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  14. ALGERA JP, Melchior C, Colomier E, Tornblom H, et al
    Hypersensitivity to the lactulose nutrient challenge test in irritable bowel syndrome - a non-invasive test of meal-related symptoms.
    Am J Gastroenterol. 2025 Nov 17. doi: 10.14309/ajg.0000000000003843.
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    September 2025
  15. TORNKVIST N, Palsson OS, Hreinsson J, Sperber AD, et al
    Global prevalence, characterization and impact of Functional Bowel Disorders.
    Am J Gastroenterol. 2025 Sep 29. doi: 10.14309/ajg.0000000000003782.
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    June 2025
  16. RAO SSC
    Fructose and Lactose Malabsorption or Intolerance or Hypersensitivity: Which Triggers Symptoms and Why?
    Am J Gastroenterol. 2025 Jun 26. doi: 10.14309/ajg.0000000000003577.
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  17. AWAD DC, Hubner DM
    The impact of violence and trauma on patient care: What the gastroenterologist needs to know.
    Am J Gastroenterol. 2025 Jun 10. doi: 10.14309/ajg.0000000000003587.
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  18. SHIHA MG, Schiepatti A, Manza F, Maimaris S, et al
    Global prevalence of celiac disease in patients with Rome III and Rome IV irritable bowel syndrome: A systematic review and meta-analysis.
    Am J Gastroenterol. 2025 Jun 10. doi: 10.14309/ajg.0000000000003586.
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  19. KARRENTO K, Lu PL, Chumpitazi BP
    Little Patients Big Discoveries: Potential Pediatric to Adult Neurogastroenterology Translation.
    Am J Gastroenterol. 2025 Jun 6. doi: 10.14309/ajg.0000000000003579.
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  20. BUSAM JA, Batta N, Shah ED, Joo L, et al
    The Safety of Pharmacotherapy for Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis.
    Am J Gastroenterol. 2025 Jun 5. doi: 10.14309/ajg.0000000000003572.
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    May 2025
  21. CALDART F, Gabriel C, Vauquelin B, Riviere P, et al
    Overlap of esophageal disorders of gut-brain interactions (E-DGBIs) and GERD is highly prevalent in patients with refractory reflux symptoms.
    Am J Gastroenterol. 2025 May 22. doi: 10.14309/ajg.0000000000003542.
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  22. THERRIEN A, Akula S, Galeas-Pena M, Frank E, et al
    Hereditary Alpha-Tryptasemia is Associated with Ongoing Symptoms in Individuals with Celiac Disease Despite Following a Gluten-Free Diet.
    Am J Gastroenterol. 2025 May 14. doi: 10.14309/ajg.0000000000003537.
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  23. DUGGAL S, Mahapatra S, Garrison K, Robles A, et al
    Assessing Gastrointestinal Awareness on TikTok: A Content Analysis of Colorectal Cancer, IBS, and IBD Narratives.
    Am J Gastroenterol. 2025 May 14. doi: 10.14309/ajg.0000000000003539.
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  24. SAAB O, Al-Obaidi H, Algodi M, Algodi A, et al
    Yoga for Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Am J Gastroenterol. 2025 May 13. doi: 10.14309/ajg.0000000000003524.
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  25. LI D, Yang J
    Methodological Challenges and Suggestions for Improvement in the Study of Irritable Bowel Syndrome Flora.
    Am J Gastroenterol. 2025 May 2. doi: 10.14309/ajg.0000000000003489.
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    April 2025
  26. WEI J, Zhong Y, Li Y, Li J, et al
    Addressing Mechanistic and Subtype-specific Limitations in the Study on Fecal Proteolytic Bacteria and Staphylococcal Superantigens in Irritable Bowel Syndrome.
    Am J Gastroenterol. 2025 Apr 28. doi: 10.14309/ajg.0000000000003453.
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  27. CAMILLERI M
    When and What to Test for Diarrhea: Focus on Stool Testing.
    Am J Gastroenterol. 2025;120:778-784.
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  28. WALLEN H, Ljotsson B, Lindfors P, Forsell E, et al
    Internet-Delivered Exposure-Based Cognitive Behavior Therapy for Irritable Bowel Syndrome: A Clinical Effectiveness Study.
    Am J Gastroenterol. 2025;120:856-863.
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    December 2024
  29. PARK CJ, Jones MP, Prott G, Sequeira C, et al
    Rome IV Functional Defecation Disorder: Time for a Change in Symptom Criteria for Improved Clinical Relevance?
    Am J Gastroenterol. 2024;120:2165-2172.
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  30. LIU J, Lv C, Yin M, Zhu M, et al
    Efficacy and safety of transcutaneous auricular vagus nerve stimulation in patients with constipation-predominant irritable bowel syndrome: a single-center, single-blind, randomized controlled trial.
    Am J Gastroenterol. 2024 Dec 17. doi: 10.14309/ajg.0000000000003257.
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    November 2024
  31. NYBACKA S, Colomier E, Hreinsson JP, Storsrud S, et al
    Dietary intake and quality in irritable bowel syndrome: a comparative study with controls and the association with symptom severity.
    Am J Gastroenterol. 2024 Nov 27. doi: 10.14309/ajg.0000000000003249.
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  32. BALSIGER LM, Santos J, Serra J, Piessevaux H, et al
    A Phase II, multicentric, randomized, double-blind, placebo controlled, proof of concept study of efficacy and safety of Rifamycin SV-MMX(R) 600 mg tablets administered three or two times daily to patients with diarrhea-predominant irritable bowel syn
    Am J Gastroenterol. 2024 Nov 26. doi: 10.14309/ajg.0000000000003236.
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    September 2024
  33. KERBAGE A, Loesch J, Hamza E, Khan S, et al
    Evaluating Equity in Clinical Trial Accessibility: An Analysis of Demographic, Socioeconomic, and Educational Disparities in IBS Drug Trials.
    Am J Gastroenterol. 2024 Sep 24. doi: 10.14309/ajg.0000000000003099.
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  34. BOSMAN M, Vork L, Jonkers D, Snijkers J, et al
    Results from a psychometric validation study: irritable bowel syndrome patients report higher symptom burden using end-of-day versus real-time assessment.
    Am J Gastroenterol. 2024 Sep 23. doi: 10.14309/ajg.0000000000003091.
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  35. JONES MP, Koloski NA, Walker MM, Holtmann GJ, et al
    A Minority of Childhood Disorders of Gut-Brain Interaction Persist Into Adulthood: A Risk-Factor Analysis.
    Am J Gastroenterol. 2024;119:1894-1900.
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    August 2024
  36. QUAN R, Decraecker L, Appeltans I, Cuende-Estevez M, et al
    Fecal Proteolytic Bacteria and Staphylococcal Superantigens are Associated with Abdominal Pain Severity in Irritable Bowel Syndrome.
    Am J Gastroenterol. 2024 Aug 21. doi: 10.14309/ajg.0000000000003042.
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    July 2024

  37. Correction to: The Role of Food in the Treatment of Bowel Disorders: Focus on Irritable Bowel Syndrome and Functional Constipation.
    Am J Gastroenterol. 2024;119:1442-1444.
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    June 2024
  38. ANDERSON EJ, Peters SL, Gibson PR, Halmos EP, et al
    Comparison of digitally-delivered gut-directed hypnotherapy program to an active control for irritable bowel syndrome.
    Am J Gastroenterol. 2024 Jun 28. doi: 10.14309/ajg.0000000000002921.
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    May 2024
  39. TUNALI V, Arslan NC, Ermis BH, Hakim GD, et al
    A Multicenter Randomized Controlled Trial Of Microbiome-Based Artificial Intelligence-Assisted Personalized Diet Vs Low Fodmap Diet: A Novel Approach for the Management of Irritable Bowel Syndrome.
    Am J Gastroenterol. 2024 May 8. doi: 10.14309/ajg.0000000000002862.
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    April 2024
  40. HANNA-JAIRALA I, Drossman DA
    CENTRAL NEUROMODULATORS IN IRRITABLE BOWEL SYNDROME. WHY, HOW AND WHEN.
    Am J Gastroenterol. 2024 Apr 9. doi: 10.14309/ajg.0000000000002800.
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    March 2024
  41. CASH BD
    Congratulations. You Have Irritable Bowel Syndrome.
    Am J Gastroenterol. 2024 Mar 27. doi: 10.14309/ajg.0000000000002734.
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  42. SHIN A, Xu H
    Healthcare Costs of Irritable Bowel Syndrome (IBS) and IBS Subtypes in the United States.
    Am J Gastroenterol. 2024 Mar 14. doi: 10.14309/ajg.0000000000002753.
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    January 2024
  43. LEMBO AJ, Chey WD, Harris LA, Frazier R, et al
    Abdominal Symptom Improvement During Clinical Trials of Tenapanor in Patients With Irritable Bowel Syndrome With Constipation: A Post Hoc Analysis.
    Am J Gastroenterol. 2024 Jan 31. doi: 10.14309/ajg.0000000000002685.
    >> Share

  44. LI F, Yano Y, Etievant L, Daniel CR, et al
    The Time-Dependent Association between Irritable Bowel Syndrome and All-cause and Cause-specific Mortality: A Prospective Cohort Study within the UK Biobank.
    Am J Gastroenterol. 2024 Jan 26. doi: 10.14309/ajg.0000000000002675.
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  45. VAN TILBURG MAL, Rana H
    Well-Being of Patients With Irritable Bowel Syndrome: A Shift From Measuring Deficits to Strengths?
    Am J Gastroenterol. 2024 Jan 2. doi: 10.14309/ajg.0000000000002601.
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  46. American College of Gastroenterology Monograph on Microbiome Therapeutics.
    Am J Gastroenterol. 2024;119.
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    October 2023
  47. SNIJKERS JTW, Winkens B, Weerts ZZRM, Vork L, et al
    Satisfaction with life in IBS is associated with psychological burden rather than gastrointestinal symptom severity.
    Am J Gastroenterol. 2023 Oct 4. doi: 10.14309/ajg.0000000000002547.
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    September 2023
  48. TOPAN R, Vork L, Fitzke BSocSci H, Pandya S, et al
    Poor subjective sleep quality predicts symptoms in Irritable Bowel Syndrome using the Experience Sampling Method.
    Am J Gastroenterol. 2023 Sep 22. doi: 10.14309/ajg.0000000000002510.
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    May 2023
  49. KHAN Z
    Continuing Medical Education Questions: May 2023.
    Am J Gastroenterol. 2023;118:779.
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    April 2023
  50. BALLOU S, Rangan V, Eidelberg A, Proctor S, et al
    What is unspecified functional bowel disorder? A commonly seen, rarely recognized, and poorly understood diagnosis.
    Am J Gastroenterol. 2023 Apr 13. doi: 10.14309/ajg.0000000000002281.
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  51. YANG PL, Kamp KJ, Burr RL, Tang HJ, et al
    Age Differences in Core Symptoms and Symptom Relationships in Patients with Irritable Bowel Syndrome: A Network Analysis.
    Am J Gastroenterol. 2023 Apr 11. doi: 10.14309/ajg.0000000000002280.
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    February 2023
  52. SALEH ZM, Chey WD, Berry S
    Behavioral Health Digital Therapeutics for Patients with Irritable Bowel Syndrome: A Primer for Gastroenterologists.
    Am J Gastroenterol. 2023 Feb 16. doi: 10.14309/ajg.0000000000002220.
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    January 2023
  53. DAMIANOS JA, Tomar SK, Azpiroz F, Barba E, et al
    Abdominophrenic Dyssynergia: A Narrative Review.
    Am J Gastroenterol. 2023;118:41-45.
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    December 2022
  54. BAI T, Xu Z, Xia P, Feng Y, et al
    The Short-term Efficacy of Bifidobacterium Quadruple Viable Tablet in Patients with Diarrhea-Predominant Irritable Bowel Syndrome: Potentially Mediated by Metabolism rather than Diversity Regulation.
    Am J Gastroenterol. 2022 Dec 23. doi: 10.14309/ajg.0000000000002147.
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  55. GEARRY R, Fukudo S, Barbara G, Kuhn-Sherlock B, et al
    Consumption of two green kiwifruit daily improves constipation and abdominal comfort - results of an international multicentre randomised controlled trial.
    Am J Gastroenterol. 2022 Dec 20. doi: 10.14309/ajg.0000000000002124.
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  56. JONES MP, Guthrie-Lyons L, Sato YA, Talley NJ, et al
    Factors Associated With Placebo Treatment Response in Functional Dyspepsia Clinical Trials.
    Am J Gastroenterol. 2022 Dec 20. doi: 10.14309/ajg.0000000000002097.
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  57. SPIEGEL B
    Gravity and the Gut: A Hypothesis of Irritable Bowel Syndrome.
    Am J Gastroenterol. 2022;117:1933-1947.
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    November 2022
  58. D'SILVA A, Marshall DA, Vallance JK, Nasser Y, et al
    Meditation and Yoga for Irritable Bowel Syndrome: A Randomized Clinical Trial.
    Am J Gastroenterol. 2022 Nov 25. doi: 10.14309/ajg.0000000000002052.
    >> Share

    October 2022
  59. BRENNER DM, Lacy BE, Ford AC, Bartolini W, et al
    Linaclotide Reduced Response Time for Irritable Bowel Syndrome with Constipation Symptoms: Analysis of Four Randomized Controlled Trials.
    Am J Gastroenterol. 2022 Oct 12. pii: 00000434-990000000-00551.
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    September 2022
  60. VILLANUEVA-MILLAN MJ, Leite G, Wang J, Morales W, et al
    Methanogens and Hydrogen Sulfide Producing Bacteria Guide Distinct Gut Microbe Profiles and Irritable Bowel Syndrome Subtypes.
    Am J Gastroenterol. 2022 Sep 6. pii: 00000434-990000000-00500.
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    August 2022
  61. NORDIN E, Hellstrom PM, Brunius C, Landberg R, et al
    Modest conformity between self-reporting of Bristol stool form and fecal consistency measured by stool water content in irritable bowel syndrome, a FODMAP and gluten trial.
    Am J Gastroenterol. 2022 Aug 12. pii: 00000434-990000000-00449.
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    July 2022
  62. VOLLEBREGT PF, Wiklendt L, Burgell RE, Chaichanavichkij P, et al
    Abnormal Perception of Urge to Defecate: An Important Pathophysiological Mechanism in Women With Chronic Constipation.
    Am J Gastroenterol. 2022;117:1125-1136.
    >> Share

    June 2022
  63. HUANG Z, Lin Z, Lin C, Chu H, et al
    Transcutaneous Electrical Acustimulation Improves Irritable Bowel Syndrome with Constipation by Accelerating Colon Transit and Reducing Rectal Sensation via Autonomic Mechanisms.
    Am J Gastroenterol. 2022 Jun 17. pii: 00000434-990000000-00418.
    >> Share

  64. TACK J, Tornblom H, Tan V, Carbone F, et al
    Evidence-Based and Emerging Dietary Approaches to Upper Disorders of Gut-Brain Interaction.
    Am J Gastroenterol. 2022;117:965-972.
    >> Share

    May 2022
  65. VAN DEN HOUTE K, Bercik P, Simren M, Tack J, et al
    Mechanisms underlying food-triggered symptoms in disorders of gut-brain interactions.
    Am J Gastroenterol. 2022 May 4. pii: 00000434-990000000-00357.
    >> Share

  66. DULANEY DT
    Continuing Medical Education Questions: May 2022.
    Am J Gastroenterol. 2022;117:720.
    >> Share

  67. LACY BE, Cangemi DJ
    A Pragmatic Approach to the Evaluation and Treatment of Abdominal Bloating.
    Am J Gastroenterol. 2022;117:701-705.
    >> Share

    April 2022
  68. ZHANG X, Xiao X, Yang JL
    Shall we reduce endoscopy in patients with irritable bowel syndrome?
    Am J Gastroenterol. 2022 Apr 15. pii: 00000434-990000000-00342.
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  69. SINGH P, Tuck C, Gibson PR, Chey WD, et al
    The Role of Food in the Treatment of Bowel Disorders: Focus on Irritable Bowel Syndrome and Functional Constipation.
    Am J Gastroenterol. 2022 Apr 8. pii: 00000434-990000000-00347.
    >> Share

  70. BRENNER DM, Harris LA, Chang CH, Waldman SA, et al
    Real-World Treatment Strategies to Improve Outcomes in Patients With Chronic Idiopathic Constipation and Irritable Bowel Syndrome With Constipation.
    Am J Gastroenterol. 2022;117.
    >> Share

  71. KASSEBAUM-LADEWSKI A, Poppers DM, Brenner DM
    Effective Communication Strategies and Tools for Improving Treatment Outcomes in Patients With Chronic Idiopathic Constipation and Irritable Bowel Syndrome With Constipation.
    Am J Gastroenterol. 2022;117.
    >> Share

  72. SAYUK GS, Waldman SA, Brenner DM
    Mechanisms of Action of Current Pharmacologic Options for the Treatment of Chronic Idiopathic Constipation and Irritable Bowel Syndrome With Constipation.
    Am J Gastroenterol. 2022;117.
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  73. HARRIS LA, Chang CH
    Burden of Constipation: Looking Beyond Bowel Movements.
    Am J Gastroenterol. 2022;117.
    >> Share

  74. BRENNER DM
    Best Practices for the Management of Chronic Idiopathic Constipation and Irritable Bowel Syndrome With Constipation: A Roundtable Discussion and Review.
    Am J Gastroenterol. 2022;117.
    >> Share

    March 2022
  75. PIMENTEL M, Mathur R, Wang J, Chang C, et al
    A Smartphone Application Using Artificial Intelligence Is Superior to Subject Self-Reporting When Assessing Stool Form.
    Am J Gastroenterol. 2022 Mar 14. pii: 00000434-990000000-00275.
    >> Share

  76. TAKAKURA W, Pimentel M, Rao S, Villanueva-Millan MJ, et al
    A Single Fasting Exhaled Methane Level Correlates With Fecal Methanogen Load, Clinical Symptoms and Accurately Detects Intestinal Methanogen Overgrowth.
    Am J Gastroenterol. 2022;117:470-477.
    >> Share


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