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Irritable Bowel Syndrome
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Articles published in
Aliment Pharmacol Ther
    July 2025
  1. BAILLIE S, Saxena S, Jayasooriya N, Bottle A, et al
    Pain and Sedative Medication Use Among Individuals With Inflammatory Bowel Disease: A Nationwide Population-Based Cohort Study.
    Aliment Pharmacol Ther. 2025 Jul 2. doi: 10.1111/apt.70247.
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    April 2025
  2. KHUNSRIRAKSAKUL C, Ziegler O, Liu D, Kulaylat AS, et al
    The Impact of Antispasmodic Use on Abdominal Pain and Opioid Use in Inflammatory Bowel Disease: A Population-Based Study.
    Aliment Pharmacol Ther. 2025 Apr 11. doi: 10.1111/apt.70147.
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    February 2025
  3. CAMILLERI M, Ford AC
    Review Article: Surrogate Endpoints to Assess Treatment Efficacy in Disorders of Gut-Brain Interaction of Lower Gastrointestinal Tract.
    Aliment Pharmacol Ther. 2025 Feb 2. doi: 10.1111/apt.18527.
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    January 2025
  4. SHIN A
    Editorial: Alpha(2)-Delta Ligands in Irritable Bowel Syndrome.
    Aliment Pharmacol Ther. 2025 Jan 30. doi: 10.1111/apt.18528.
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  5. HOUGHTON LA, Gao S, Gilbert SA, Coffin B, et al
    Clinical Trial: Study to Investigate the Efficacy and Safety of the Alpha-2-Delta Ligand PD-217,014 in Patients With Irritable Bowel Syndrome.
    Aliment Pharmacol Ther. 2025 Jan 15. doi: 10.1111/apt.18487.
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    November 2024
  6. BUTT MF, Corsetti M
    Editorial: Rebuilding Rome-Revising Diagnostic Criteria for Irritable Bowel Syndrome.
    Aliment Pharmacol Ther. 2024 Nov 14. doi: 10.1111/apt.18400.
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    October 2024
  7. GOODOORY VC, Riggott C, Khasawneh M, Black CJ, et al
    Validating Simple Modifications to the Rome IV Criteria for the Diagnosis of Irritable Bowel Syndrome in Secondary Care.
    Aliment Pharmacol Ther. 2024 Oct 28. doi: 10.1111/apt.18363.
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  8. O'CONNOR A, Gill S, Neary E, White S, et al
    Impact of HADS Anxiety and Depression Scores on the Efficacy of Dietary Interventions for Irritable Bowel Syndrome.
    Aliment Pharmacol Ther. 2024 Oct 11. doi: 10.1111/apt.18337.
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  9. RIGGOTT C, Ford AC, Gracie DJ
    Review article: The role of the gut-brain axis in inflammatory bowel disease and its therapeutic implications.
    Aliment Pharmacol Ther. 2024 Oct 5. doi: 10.1111/apt.18192.
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    August 2024
  10. SHIN A
    Editorial: Disordered eating and irritable bowel syndrome-Do maladaptive eating and weight control behaviours increase risk of a maladaptive gut?
    Aliment Pharmacol Ther. 2024 Aug 28. doi: 10.1111/apt.18232.
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  11. YANG K, Kwon S, Burton-Murray H, Kuo B, et al
    Maladaptive weight control and eating behaviours in female adolescents/young adults are associated with increased risk of irritable bowel syndrome in adulthood: Results from the Growing Up Today Study (GUTS).
    Aliment Pharmacol Ther. 2024 Aug 5. doi: 10.1111/apt.18197.
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  12. LUPIANEZ-MERLY C, Jencks K, Dilmaghani S, Ferber M, et al
    Letter (brief communication): A pilot study of hemp hull bio gut fibre (BGF) to reduce intestinal permeability in IBS-BAD.
    Aliment Pharmacol Ther. 2024;60:544-545.
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    June 2024
  13. WAIDYARATNE G, Daboul J, Liyanarachchi S, Chakraborty S, et al
    The evaluation and analysis of irritable bowel syndrome-related short videos on social media (TikTok).
    Aliment Pharmacol Ther. 2024 Jun 10. doi: 10.1111/apt.18096.
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  14. SPERBER AD, Freud T, Palsson OS, Bangdiwala SI, et al
    The aging gastrointestinal tract: Epidemiology and clinical significance of disorders of gut-brain interaction in the older general population.
    Aliment Pharmacol Ther. 2024 Jun 4. doi: 10.1111/apt.18103.
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    April 2024
  15. ALIU A, Bosch DHCA, Keszthelyi D, Rezazadeh Ardabili A, et al
    Review article: A practical approach to persistent gastrointestinal symptoms in inflammatory bowel disease in remission.
    Aliment Pharmacol Ther. 2024 Apr 8. doi: 10.1111/apt.17988.
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    February 2024
  16. STALLER K, Ludvigsson JF
    Letter: Irritable bowel syndrome and antibiotics-Authors' reply.
    Aliment Pharmacol Ther. 2024;59:422.
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  17. LONGSTRETH GF
    Letter: Irritable bowel syndrome and antibiotics.
    Aliment Pharmacol Ther. 2024;59:421.
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  18. BLACK CJ, Gracie DJ
    Editorial: A Mediterranean diet for IBS-Is healthy and inclusive eating the way forward?
    Aliment Pharmacol Ther. 2024;59:571-572.
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    January 2024
  19. SHIN A
    Editorial: Antibiotics as a risk factor for irritable bowel syndrome.
    Aliment Pharmacol Ther. 2024;59:130-131.
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  20. CHANG HC, Gau SY
    Letter: antibiotics prescription and new-onset irritable bowel syndrome.
    Aliment Pharmacol Ther. 2024;59:299.
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    December 2023
  21. STALLER K, Ludvigsson JF
    Letter: Antibiotics prescription and new-onset irritable bowel syndrome-Authors' reply.
    Aliment Pharmacol Ther. 2023 Dec 8. doi: 10.1111/apt.17827.
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    November 2023
  22. STAUDACHER HM, Mahoney S, Canale K, Opie RS, et al
    Clinical trial: A Mediterranean diet is feasible and improves gastrointestinal and psychological symptoms in irritable bowel syndrome.
    Aliment Pharmacol Ther. 2023 Nov 15. doi: 10.1111/apt.17791.
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  23. DEVENNEY J, Hasan SS, Morris J, Whorwell PJ, et al
    Clinical trial: predictive factors for response to gut-directed hypnotherapy for refractory irritable bowel syndrome, a post hoc analysis.
    Aliment Pharmacol Ther. 2023 Nov 5. doi: 10.1111/apt.17790.
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  24. EL-SALHY M, Gilja OH, Hatlebakk JG
    Letter: A step forward towards a standard FMT protocol for IBS.
    Aliment Pharmacol Ther. 2023;58:1115-1116.
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  25. LESMANA E, Grover M
    Editorial: Faecal microbiota transplantation in IBS-Moving closer or away from success?
    Aliment Pharmacol Ther. 2023;58:950-951.
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  26. SU Q, Yau YK, Ng SC
    Editorial: Faecal microbiota transplantation in IBS-Moving closer or away from success? Authors' reply.
    Aliment Pharmacol Ther. 2023;58:952-953.
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    October 2023
  27. DAJTI E, Frazzoni L, Iascone V, Secco M, et al
    Systematic review with meta-analysis: Diagnostic performance of faecal calprotectin in distinguishing inflammatory bowel disease from irritable bowel syndrome in adults.
    Aliment Pharmacol Ther. 2023 Oct 12. doi: 10.1111/apt.17754.
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    September 2023
  28. STALLER K, Olen O, Soderling J, Roelstraete B, et al
    Antibiotic use as a risk factor for irritable bowel syndrome: Results from a nationwide, case-control study.
    Aliment Pharmacol Ther. 2023 Sep 28. doi: 10.1111/apt.17736.
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  29. YAU YK, Su Q, Xu Z, Tang W, et al
    Randomised clinical trial: Faecal microbiota transplantation for irritable bowel syndrome with diarrhoea.
    Aliment Pharmacol Ther. 2023 Sep 5. doi: 10.1111/apt.17703.
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  30. MELTON SL, Halmos EP
    Editorial: One step closer to personalised nutrition therapy for irritable bowel syndrome.
    Aliment Pharmacol Ther. 2023;58:554-555.
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    August 2023
  31. CHUAH KH, Black CJ, Tee V, Lim SZ, et al
    Editorial: Recognising the regional variations in profile of irritable bowel syndrome-better late than never! Authors' reply.
    Aliment Pharmacol Ther. 2023;58:476-477.
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  32. GHOSHAL UC
    Editorial: Recognising the regional variations in profile of irritable bowel syndrome-better late than never!
    Aliment Pharmacol Ther. 2023;58:474-475.
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    July 2023
  33. LUO Y, Jodorkovsky D, Singh P, Keefer LA, et al
    Letter: determining priorities for patients with faecal incontinence and irritable bowel syndrome.
    Aliment Pharmacol Ther. 2023;58:137-138.
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  34. DAI C, Huang YH, Jiang M
    Letter: Post-COVID-19 functional dyspepsia and irritable bowel syndrome.
    Aliment Pharmacol Ther. 2023;58:126-127.
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  35. GOODOORY VC, Ng CE, Black CJ, Ford AC, et al
    Letter: determining priorities for patients with faecal incontinence and irritable bowel syndrome-authors' reply.
    Aliment Pharmacol Ther. 2023;58:139-140.
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  36. MARASCO G, Maida M, Cremon C, Barbaro MR, et al
    Letter: Post-COVID-19 functional dyspepsia and irritable bowel syndrome-Authors' reply.
    Aliment Pharmacol Ther. 2023;58:128-129.
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    June 2023
  37. SO D, Yao CK, Gill PA, Thwaites PA, et al
    Detection of changes in regional colonic fermentation in response to supplementing a low FODMAP diet with dietary fibres by hydrogen concentrations, but not by luminal pH.
    Aliment Pharmacol Ther. 2023 Jun 30. doi: 10.1111/apt.17629.
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  38. WILSON B, Kanno T, Slater R, Rossi M, et al
    Faecal and urine metabolites, but not gut microbiota, may predict response to low FODMAP diet in irritable bowel syndrome.
    Aliment Pharmacol Ther. 2023 Jun 14. doi: 10.1111/apt.17609.
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  39. GUNN D, Ford A, Farrin A, Spiller R, et al
    Editorial: ondansetron for patients with IBS-D and bowel-predominant symptoms-authors' reply.
    Aliment Pharmacol Ther. 2023;57:1337-1338.
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  40. SHAH ED
    Editorial: ondansetron for patients with IBS-D and bowel-predominant symptoms.
    Aliment Pharmacol Ther. 2023;57:1335-1336.
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  41. CHUAH KH, Black CJ, Tee V, Lim SZ, et al
    A prospective comparison of UK and Malaysian patients with irritable bowel syndrome in secondary care.
    Aliment Pharmacol Ther. 2023 Jun 1. doi: 10.1111/apt.17567.
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    May 2023
  42. GOODOORY VC, Guthrie EA, Ng CE, Black CJ, et al
    Letter: Does irritable bowel syndrome have a greater impact in Western, compared with Asian, patients? Authors' reply.
    Aliment Pharmacol Ther. 2023;57:1190-1191.
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  43. GOODOORY VC, Ng CE, Black CJ, Ford AC, et al
    Editorial: faecal incontinence is prevalent in IBS, as are effective treatment options! Authors' reply.
    Aliment Pharmacol Ther. 2023;57:1176-1177.
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  44. SHARMA A, Rao S
    Editorial: faecal incontinence is prevalent in IBS, as are effective treatment options!
    Aliment Pharmacol Ther. 2023;57:1174-1175.
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  45. CHUAH KH, Mahadeva S
    Letter: Does irritable bowel syndrome have a greater impact in Western, compared with Asian, patients?
    Aliment Pharmacol Ther. 2023;57:1188-1189.
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    April 2023
  46. MARASCO G, Maida M, Cremon C, Barbaro MR, et al
    Meta-analysis: Post-COVID-19 functional dyspepsia and irritable bowel syndrome.
    Aliment Pharmacol Ther. 2023 Apr 10. doi: 10.1111/apt.17513.
    >> Share

    March 2023
  47. GOODOORY VC, Ng CE, Black CJ, Ford AC, et al
    Prevalence and impact of faecal incontinence among individuals with Rome IV irritable bowel syndrome.
    Aliment Pharmacol Ther. 2023 Mar 13. doi: 10.1111/apt.17465.
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  48. GUNN D, Topan R, Barnard L, Fried R, et al
    Randomised, placebo-controlled trial and meta-analysis show benefit of ondansetron for irritable bowel syndrome with diarrhoea: The TRITON trial.
    Aliment Pharmacol Ther. 2023 Mar 3. doi: 10.1111/apt.17426.
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  49. THWAITES PA, Burgell RE
    Editorial: definition of factors associated with poor quality of life in patients with IBS-but where to from here?
    Aliment Pharmacol Ther. 2023;57:723-724.
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  50. GOODOORY VC, Guthrie EA, Ng CE, Black CJ, et al
    Editorial: definition of factors associated with poor quality of life in patients with IBS-but where to from here? Authors' reply.
    Aliment Pharmacol Ther. 2023;57:725-726.
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    February 2023
  51. MANTEGAZZA G, Gargari G, Guglielmetti S
    Editorial: bacterial gut symbionts as live biotherapeutic agents in irritable bowel syndrome-a rosy future despite potential long-term safety concerns.
    Aliment Pharmacol Ther. 2023;57:345-346.
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  52. QUIGLEY EMM, Stevenson A, Jeffery I, Masters J, et al
    Editorial: bacterial gut symbionts as live biotherapeutic agents in IBS-a rosy future despite potential long-term safety concerns. Authors' reply.
    Aliment Pharmacol Ther. 2023;57:347-348.
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  53. WANG L, Alexander JA
    Letter: diet-responsive or just diet-adherent in EoE. Where is the dietitian? Authors' reply.
    Aliment Pharmacol Ther. 2023;57:445.
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    January 2023
  54. MAALOUF E, Grover M
    Editorial: repurposed linaclotide and the quest for abdominal pain management in irritable bowel syndrome.
    Aliment Pharmacol Ther. 2023;57:261-262.
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    December 2022
  55. GOODOORY VC, Guthrie EA, Ng CE, Black CJ, et al
    Factors associated with lower disease-specific and generic health-related quality of life in Rome IV irritable bowel syndrome.
    Aliment Pharmacol Ther. 2022 Dec 21. doi: 10.1111/apt.17356.
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  56. FITZPATRICK JA, Halmos EP
    Editorial: gluten-free but not pain-free in IBS.
    Aliment Pharmacol Ther. 2022;56.
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  57. ALGERA JP, Magnusson MK, Ohman L, Storsrud S, et al
    Editorial: gluten-free but not pain-free in IBS-authors' reply.
    Aliment Pharmacol Ther. 2022;56.
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    November 2022
  58. QUIGLEY EMM, Markinson L, Stevenson A, Treasure FP, et al
    Randomised clinical trial: efficacy and safety of the live biotherapeutic product MRx1234 in patients with irritable bowel syndrome.
    Aliment Pharmacol Ther. 2022 Nov 11. doi: 10.1111/apt.17310.
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  59. LEMBO A, Kuo B, Boinpally R, Li E, et al
    Randomised clinical trial: effects of MD-7246 on irritable bowel syndrome with diarrhoea.
    Aliment Pharmacol Ther. 2022 Nov 2. doi: 10.1111/apt.17274.
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  60. QUIGLEY EMM
    Editorial: 5-aminosalicylic acid fails to impact on irritable bowel syndrome-wrong population, intervention, target or hypothesis?
    Aliment Pharmacol Ther. 2022;56:1497-1498.
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    October 2022
  61. GU Y, Xiang Y
    Letter: efficacy of peppermint oil in irritable bowel syndrome.
    Aliment Pharmacol Ther. 2022;56:1215-1216.
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  62. INGROSSO MR, Ianiro G, Nee J, Lembo AJ, et al
    Letter: efficacy of peppermint oil in irritable bowel syndrome-authors' reply.
    Aliment Pharmacol Ther. 2022;56:1217-1218.
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  63. SHIN A
    Editorial: natural history of irritable bowel syndrome in inflammatory bowel disease.
    Aliment Pharmacol Ther. 2022;56:1300-1301.
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  64. FAIRBRASS KM, Hamlin PJ, Gracie DJ, Ford AC, et al
    Editorial: natural history of irritable bowel syndrome in inflammatory bowel disease-authors' reply.
    Aliment Pharmacol Ther. 2022;56:1302-1303.
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    September 2022
  65. ALGERA JP, Magnusson MK, Ohman L, Storsrud S, et al
    Randomised controlled trial: effects of gluten-free diet on symptoms and the gut microenvironment in irritable bowel syndrome.
    Aliment Pharmacol Ther. 2022 Sep 29. doi: 10.1111/apt.17239.
    >> Share

  66. GOODOORY VC, Ng CE, Black CJ, Ford AC, et al
    Editorial: work and activity impairment are important considerations to optimise treatment plans for irritable bowel syndrome. Authors' reply.
    Aliment Pharmacol Ther. 2022;56:894-895.
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  67. SHAH ED, Wechsler EV
    Editorial: work and activity impairment are important considerations to optimise treatment plans for irritable bowel syndrome.
    Aliment Pharmacol Ther. 2022;56:892-893.
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    August 2022
  68. FAIRBRASS KM, Hamlin PJ, Gracie DJ, Ford AC, et al
    Natural history and impact of irritable bowel syndrome-type symptoms in inflammatory bowel disease during 6 years of longitudinal follow-up.
    Aliment Pharmacol Ther. 2022 Aug 22. doi: 10.1111/apt.17193.
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  69. INGROSSO MR, Ianiro G, Nee J, Lembo AJ, et al
    Systematic review and meta-analysis: efficacy of peppermint oil in irritable bowel syndrome.
    Aliment Pharmacol Ther. 2022 Aug 9. doi: 10.1111/apt.17179.
    >> Share

  70. CASTRO TEJERA V, Ohman L, Aabakken L, Fellstrom B, et al
    Randomised clinical trial and meta-analysis: mesalazine treatment in irritable bowel syndrome-Effects on gastrointestinal symptoms and rectal biomarkers of immune activity.
    Aliment Pharmacol Ther. 2022 Aug 8. doi: 10.1111/apt.17182.
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    July 2022
  71. GOODOORY VC, Ng CE, Black CJ, Ford AC, et al
    Impact of Rome IV Irritable Bowel Syndrome on Work and Activities of Daily Living.
    Aliment Pharmacol Ther. 2022 Jul 6. doi: 10.1111/apt.17132.
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  72. LOVDAHL J, Tornblom H, Ringstrom G, Palsson OS, et al
    Editorial: group-based hypnotherapy as good as individually delivered hypnotherapy for symptoms of irritable bowel syndrome-authors' reply.
    Aliment Pharmacol Ther. 2022;56:160-161.
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  73. MIKOCKA-WALUS A, Lores T
    Editorial: group-based hypnotherapy as good as individually delivered hypnotherapy for symptoms of irritable bowel syndrome.
    Aliment Pharmacol Ther. 2022;56:158-159.
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  74. BIESIEKIERSKI JR, Wu J, Van Oudenhove L
    Letter: gut-brain axis dysfunction underlies symptom generation in irritable bowel syndrome-a plea for rational interpretation of irrational doses of FODMAPs. Authors' reply.
    Aliment Pharmacol Ther. 2022;56:368-369.
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  75. HALMOS EP, Gibson PR
    Letter: gut-brain axis dysfunction underlies symptom generation in irritable bowel syndrome-a plea for rational interpretation of irrational doses of FODMAPs.
    Aliment Pharmacol Ther. 2022;56:366-367.
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  76. BIESIEKIERSKI JR, Manning LP, Murray HB, Vlaeyen JWS, et al
    Review article: Exclude or expose? The paradox of conceptually opposite treatments for irritable bowel syndrome.
    Aliment Pharmacol Ther. 2022 Jul 1. doi: 10.1111/apt.17111.
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    June 2022
  77. COFFIN PB, Duboc H
    Diagnostic and therapeutic approach to persistent abdominal pain beyond irritable bowel syndrome.
    Aliment Pharmacol Ther. 2022 Jun 2. doi: 10.1111/apt.17064.
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  78. GOODOORY VC, Ng CE, Black CJ, Ford AC, et al
    Editorial: estimating the costs of care in irritable bowel syndrome-a necessary step to enhance value-based care for a high-prevalence, low-cost condition. Authors' reply.
    Aliment Pharmacol Ther. 2022;55:1590-1591.
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  79. BERINSTEIN JA, Fendrick AM
    Editorial: estimating the costs of care in irritable bowel syndrome-a necessary step to enhance value-based care for a high-prevalence, low-cost condition.
    Aliment Pharmacol Ther. 2022;55:1588-1589.
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    May 2022
  80. LOVDAHL J, Tornblom H, Ringstrom G, Palsson OS, et al
    Randomised clinical trial: individual versus group hypnotherapy for irritable bowel syndrome.
    Aliment Pharmacol Ther. 2022 May 3. doi: 10.1111/apt.16934.
    >> Share

  81. QUIGLEY EMM
    Editorial: risky business. What do sufferers' perceptions of risk from interventions for irritable bowel syndrome really mean?
    Aliment Pharmacol Ther. 2022;55:1218-1219.
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  82. GOODOORY VC, Ng CE, Black CJ, Ford AC, et al
    Direct healthcare costs of Rome IV or Rome III-defined irritable bowel syndrome in the United Kingdom.
    Aliment Pharmacol Ther. 2022 May 1. doi: 10.1111/apt.16939.
    >> Share

    April 2022
  83. FOX M
    Editorial: meal-induced symptoms in irritable bowel syndrome-"all in the mind"?
    Aliment Pharmacol Ther. 2022;55:880-881.
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