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Hypersensitivity Reaction
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Articles published in
Proc Natl Acad Sci U S A
    February 2024
  1. KLINE SN, Orlando NA, Lee AJ, Wu MJ, et al
    Staphylococcus aureus proteases trigger eosinophil-mediated skin inflammation.
    Proc Natl Acad Sci U S A. 2024;121:e2309243121.
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    December 2023
  2. WEN J, Heft-Neal S, Baylis P, Boomhower J, et al
    Quantifying fire-specific smoke exposure and health impacts.
    Proc Natl Acad Sci U S A. 2023;120:e2309325120.
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  3. KUMAGAI J, Kiuchi M, Kokubo K, Yagyu H, et al
    The USP7-STAT3-granzyme-Par-1 axis regulates allergic inflammation by promoting differentiation of IL-5-producing Th2 cells.
    Proc Natl Acad Sci U S A. 2023;120:e2302903120.
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    September 2023
  4. HEFT-NEAL S, Gould CF, Childs ML, Kiang MV, et al
    Emergency department visits respond nonlinearly to wildfire smoke.
    Proc Natl Acad Sci U S A. 2023;120:e2302409120.
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    June 2023
  5. HUANG Q, Lariviere PJ, Powell JE, Moran NA, et al
    Engineered gut symbiont inhibits microsporidian parasite and improves honey bee survival.
    Proc Natl Acad Sci U S A. 2023;120:e2220922120.
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    May 2023
  6. SINESHCHEKOV OA, Govorunova EG, Li H, Wang Y, et al
    Sequential absorption of two photons creates a bistable form of RubyACR responsible for its strong desensitization.
    Proc Natl Acad Sci U S A. 2023;120:e2301521120.
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    December 2022
  7. SHAH SD, Lind C, De Pascali F, Penn RB, et al
    In silico identification of a beta(2)-adrenoceptor allosteric site that selectively augments canonical beta(2)AR-Gs signaling and function.
    Proc Natl Acad Sci U S A. 2022;119:e2214024119.
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  8. GOH JPZ, Ruchti F, Poh SE, Koh WLC, et al
    The human pathobiont Malassezia furfur secreted protease Mfsap1 regulates cell dispersal and exacerbates skin inflammation.
    Proc Natl Acad Sci U S A. 2022;119:e2212533119.
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    November 2022
  9. TANIOKU T, Nishibata M, Tokinaga Y, Konno K, et al
    Tmem45b is essential for inflammation- and tissue injury-induced mechanical pain hypersensitivity.
    Proc Natl Acad Sci U S A. 2022;119:e2121989119.
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    October 2022
  10. ZHUANG Y, Noviello CM, Hibbs RE, Howard RJ, et al
    Differential interactions of resting, activated, and desensitized states of the alpha7 nicotinic acetylcholine receptor with lipidic modulators.
    Proc Natl Acad Sci U S A. 2022;119:e2208081119.
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    August 2022
  11. OYAMA K, Zeeb V, Yamazawa T, Kurebayashi N, et al
    Heat-hypersensitive mutants of ryanodine receptor type 1 revealed by microscopic heating.
    Proc Natl Acad Sci U S A. 2022;119:e2201286119.
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  12. MERRITT DM, MacKay-Clackett I, Almeida SMT, Tran C, et al
    Arrestin-mediated desensitization enables intraneuronal olfactory discrimination in Caenorhabditis elegans.
    Proc Natl Acad Sci U S A. 2022;119:e2116957119.
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    July 2022
  13. BOUCHATTA O, Aby F, Sifeddine W, Bouali-Benazzouz R, et al
    Pain hypersensitivity in a pharmacological mouse model of attention-deficit/hyperactivity disorder.
    Proc Natl Acad Sci U S A. 2022;119:e2114094119.
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  14. ZHANG L, Hobeika CS, Khabibullin D, Yu D, et al
    Hypersensitivity to ferroptosis in chromophobe RCC is mediated by a glutathione metabolic dependency and cystine import via solute carrier family 7 member 11.
    Proc Natl Acad Sci U S A. 2022;119:e2122840119.
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  15. LANGLEY DB, Schofield P, Nevoltris D, Jackson J, et al
    Genetic and structural basis of the human anti-alpha-galactosyl antibody response.
    Proc Natl Acad Sci U S A. 2022;119:e2123212119.
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  16. HOWE LC, Hardebeck EJ, Eberhardt JL, Markus HR, et al
    White patients' physical responses to healthcare treatments are influenced by provider race and gender.
    Proc Natl Acad Sci U S A. 2022;119:e2007717119.
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    June 2022
  17. ZHOU YW, Sun J, Wang Y, Chen CP, et al
    Tas2R activation relaxes airway smooth muscle by release of Galphat targeting on AChR signaling.
    Proc Natl Acad Sci U S A. 2022;119:e2121513119.
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  18. MAGNAYE KM, Clay SM, Nicodemus-Johnson J, Naughton KA, et al
    DNA methylation signatures in airway cells from adult children of asthmatic mothers reflect subtypes of severe asthma.
    Proc Natl Acad Sci U S A. 2022;119:e2116467119.
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  19. WANG WL, Kasamatsu J, Joshita S, Gilfillan S, et al
    The aryl hydrocarbon receptor instructs the immunomodulatory profile of a subset of Clec4a4(+) eosinophils unique to the small intestine.
    Proc Natl Acad Sci U S A. 2022;119:e2204557119.
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    April 2022
  20. MAIZELS RM
    Ascarosides from helminths pack a punch against allergy.
    Proc Natl Acad Sci U S A. 2022;119:e2202250119.
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    March 2022
  21. GU P, Wang F, Shang Y, Liu J, et al
    Nociception and hypersensitivity involve distinct neurons and molecular transducers in Drosophila.
    Proc Natl Acad Sci U S A. 2022;119:e2113645119.
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  22. SHINODA K, Choe A, Hirahara K, Kiuchi M, et al
    Nematode ascarosides attenuate mammalian type 2 inflammatory responses.
    Proc Natl Acad Sci U S A. 2022;119.
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    February 2022
  23. EAGLES DA, Saez NJ, Krishnarjuna B, Bradford JJ, et al
    A peptide toxin in ant venom mimics vertebrate EGF-like hormones to cause long-lasting hypersensitivity in mammals.
    Proc Natl Acad Sci U S A. 2022;119.
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    January 2022
  24. JOHNSON MT, Xin P, Benson JC, Pathak T, et al
    STIM1 is a core trigger of airway smooth muscle remodeling and hyperresponsiveness in asthma.
    Proc Natl Acad Sci U S A. 2022;119.
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    October 2021
  25. DUTTA J, Rehman R, Vellarikkal SK, Fredenburgh LE, et al
    Possible selection bias limits the interpretation of single-cell transcriptomics data of steroid-resistant asthma exacerbation.
    Proc Natl Acad Sci U S A. 2021;118.
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    September 2021
  26. ZHANG C, Chinnappan M, Prestwood CA, Edwards M, et al
    Interleukins 4 and 13 drive lipid abnormalities in skin cells through regulation of sex steroid hormone synthesis.
    Proc Natl Acad Sci U S A. 2021;118.
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  27. SCHEER FAJL, Hilton MF, Evoniuk HL, Shiels SA, et al
    The endogenous circadian system worsens asthma at night independent of sleep and other daily behavioral or environmental cycles.
    Proc Natl Acad Sci U S A. 2021;118.
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    March 2021
  28. VOISIN T, Perner C, Messou MA, Shiers S, et al
    The CysLT2R receptor mediates leukotriene C4-driven acute and chronic itch.
    Proc Natl Acad Sci U S A. 2021;118.
    >> Share


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