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Hypertension

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Articles published in
J Am Coll Cardiol
    May 2026
  1. LAM EL, Khan SS, Shah NS
    Hypertensive Disorders of Pregnancy in the United States, 2016-2024.
    J Am Coll Cardiol. 2026 May 13:S0735-1097(26)06133.
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  2. ABDALLA M, Juraschek SP, Biaggioni I, Bowling CB, et al
    Blood Pressure Assessment Across the Lifespan: Improving Clinical Research and Clinical Practice: A National Heart, Lung, and Blood Institute Workshop Report.
    J Am Coll Cardiol. 2026;87:2524-2542.
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  3. KUKUEV A, Ravid D, Rader F
    Injectables for the Treatment of Hypertension: A Look Into the Future?
    J Am Coll Cardiol. 2026;87:2521-2523.
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  4. PARATI G, Croce A, Pengo M, Bilo G, et al
    Bridging the Gap Between Clinical Trials and Daily Practice in Managing Hypertension in Older Adults: Are Digital Tools the Key?
    J Am Coll Cardiol. 2026;87:2485-2488.
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  5. KRUMHOLZ HM
    When "Intensive" Becomes Standard: Hypertension, Stroke, and the Cost of Clinical Inertia.
    J Am Coll Cardiol. 2026;87:2335-2337.
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  6. CHOI K, Kim C, Spatz ES, Krumholz HM, et al
    Single-Pill Combination Therapy for Hypertension: Persistent Underuse in the United States, 2015-2025.
    J Am Coll Cardiol. 2026 May 6:S0735-1097(26)06011.
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    April 2026
  7. ZHANG Y, Zhang S, Wang Y, Spatz ES, et al
    Low-Level Airborne Particulate Matter and Risk of Hypertension Hospitalization in Older U.S. Adults.
    J Am Coll Cardiol. 2026 Apr 8:S0735-1097(26)05646.
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  8. PENG X, Song Q, Bai J, Liu Y, et al
    Blood Pressure Trajectories and Cardiovascular Outcomes in Older Patients: Insights From the STEP Trial.
    J Am Coll Cardiol. 2026 Apr 1:S0735-1097(26)05644.
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    March 2026
  9. SPATZ ES, Jones DW
    Bending the Curve in Hypertension Management: It Is Time for a Fundamentally Different Approach.
    J Am Coll Cardiol. 2026 Mar 31:S0735-1097(26)05496.
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  10. LAFFIN LJ, Wang Q, Sarraju A, Touyz RM, et al
    Efficacy of Tonlamarsen in Patients With Uncontrolled Hypertension: The KARDINAL Phase 2 Randomized Clinical Trial.
    J Am Coll Cardiol. 2026 Mar 28:S0735-1097(26)05806.
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  11. LJUNGBERG C, Carlsson B, Shojaiyan P, Franzen S, et al
    Renin-Aldosterone Profiles and Cardiorenal Outcomes in Hypertension: A Nationwide Cohort Study.
    J Am Coll Cardiol. 2026 Mar 25:S0735-1097(26)00235.
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  12. PENG Y, Li Y, Li S, Zhang L, et al
    Achieving Intensive Blood Pressure Control in High-Risk Patients: Implementation Insights From the ESPRIT Trial.
    J Am Coll Cardiol. 2026 Mar 19:S0735-1097(26)05233.
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  13. O'CONNELL SS, Whelton PK, Li F, Allouch F, et al
    Global Hypertension 2000 to 2020: Trends, Disparities, and Progress in Awareness, Treatment, and Control.
    J Am Coll Cardiol. 2026 Mar 12:S0735-1097(26)00295.
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  14. KHAN MS, Borlaug BA, Butler J, Gomberg-Maitland M, et al
    Pulmonary Hypertension Associated With Left Heart Disease: Challenges, Emerging Strategies, and Future Directions.
    J Am Coll Cardiol. 2026 Mar 11:S0735-1097(26)00134.
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  15. HAHAD O, Rajagopalan S, Daiber A, Al-Kindi S, et al
    Hypertension as a Vulnerable Disease State Under Environmental Stress.
    J Am Coll Cardiol. 2026 Mar 10:S0735-1097(26)05487.
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  16. REDDY YNV, Frantz RP, Miranda WR, Harada T, et al
    Sotatercept in Pulmonary Arterial Hypertension: Central, Hematologic, and Peripheral Mechanisms of Benefit.
    J Am Coll Cardiol. 2026 Mar 2:S0735-1097(26)05633.
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    February 2026
  17. ZHENG Y, Xu R, Sun H, Liu Y, et al
    Rethinking Ambient Air Pollution and Hypertension Risk: The Importance of Disease Severity.
    J Am Coll Cardiol. 2026 Feb 25:S0735-1097(26)00230.
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  18. O'HAGAN E, Livingstone A, Gadsden T, Usherwood T, et al
    Preferences for Antihypertensive Prescribing in Older Adults: A Discrete Choice Experiment.
    J Am Coll Cardiol. 2026 Feb 24:S0735-1097(26)00216.
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  19. XUE X, Zhou Z, Luo H, Gao Y, et al
    Short-Term Exposure to Air Pollution Increases Mortality From Hypertension and its Multiorgan Complications: A Case Crossover Study of 2.1 Million Deaths in China.
    J Am Coll Cardiol. 2026 Feb 17:S0735-1097(26)00058.
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  20. ZHEUTLIN AR, Shimbo D, Bress AP
    Small But Mighty: Blood Pressure Control Through Ultra-Low-Dose Single-Pill Antihypertensive Medication as Initial Therapy.
    J Am Coll Cardiol. 2026 Feb 16:S0735-1097(25)10657.
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  21. SUNG KC, Park K, Kim DH, Lim SW, et al
    Single-Pill Low-Dose Triple Combination Therapy vs Standard-Dose Monotherapy in Patients With Mild-to-Moderate Hypertension.
    J Am Coll Cardiol. 2026 Feb 3:S0735-1097(25)10559.
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  22. KREUTZ R, Brunstrom M
    Beyond the RAAS: The Search for Novel Antihypertensive Therapies: A Needle in the Haystack?
    J Am Coll Cardiol. 2026 Feb 3:S0735-1097(25)10581.
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    January 2026
  23. WANG S, Wang K, Gu H, Zhang J, et al
    Blood Pressure Levels and Outcomes in Type 2 Diabetes: Dose-Response Meta-Analysis of 5.87 Million Cohort Participants.
    J Am Coll Cardiol. 2026 Jan 14:S0735-1097(25)10148.
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  24. WHITE WB, Azizi M, Ferdinand K, Cohen DL, et al
    Natriuretic Peptide Receptor-1 Agonist for Resistant Hypertension: A Randomized Phase 2 Trial.
    J Am Coll Cardiol. 2026 Jan 13:S0735-1097(25)10351.
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    December 2025
  25. KRUMHOLZ HM
    Heart Failure and Hypertension in the Metabolic Era: 2 Atlases, 1 Message.
    J Am Coll Cardiol. 2025;86:2539-2541.
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  26. BANIGBE BF, Moran AE, Gupta R, Cazabon D, et al
    Lessons Learned From Treating 34 Million People With Hypertension: The Global HEARTS Initiative.
    J Am Coll Cardiol. 2025;86:2374-2387.
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  27. GETACHEW ED, Onuma OK
    Addressing Sub-Saharan Africa's Hypertension Care Crisis Through a Data-Driven Approach.
    J Am Coll Cardiol. 2025;86:2289-2291.
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  28. NAMBIEMA A, Agboyibor KM, Dangou JM, Antignac M, et al
    Prevalence, Awareness, and Treatment of Hypertension in 37 African Countries: Trends From 2003 to 2022.
    J Am Coll Cardiol. 2025;86:2263-2288.
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  29. BARNES GD, Lee H, Berlacher K
    Understanding Why Aspirin Is Underutilized for Hypertensive Disorders of Pregnancy: Lessons Learned in Nigeria.
    J Am Coll Cardiol. 2025;86:2260-2262.
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    November 2025
  30. LEE HH, Crawford EB, Cho SMJ, Krawisz AK, et al
    Trends in Prevalence, Treatment, and Control of Cardiometabolic Risk Factors Among Adults With Hypertension in the United States, 1999-2023.
    J Am Coll Cardiol. 2025 Nov 26:S0735-1097(25)09917.
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  31. SUZUKI T, Fukui S, Yoneoka D, Aoki J, et al
    Blood Pressure After Changes in Light-to-Moderate Alcohol Consumption in Women and Men: Longitudinal Japanese Annual Checkup Analysis.
    J Am Coll Cardiol. 2025;86:2031-2044.
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  32. DODSON JA, Adhikari S, Schoenthaler AM, Shimbo D, et al
    Behavioral Economics and Medication Adherence for Hypertension: A Randomized Clinical Trial.
    J Am Coll Cardiol. 2025 Nov 18:S0735-1097(25)10073.
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  33. ROY A, Prabhakaran D
    India's Hypertension Challenge: Young, Diverse, and Undermanaged.
    J Am Coll Cardiol. 2025;86:1523-1525.
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  34. WU Y, Neal B, Miranda JJ, Labarthe D, et al
    Salt Substitution for Hypertension and Cardiovascular Disease Prevention: The SSaSS Trial and Beyond.
    J Am Coll Cardiol. 2025;86:1504-1506.
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  35. MENG X, Rajagopalan S, Brook RD, Zhang S, et al
    The Pressure Is Rising: Emerging Environmental Determinants of Hypertension.
    J Am Coll Cardiol. 2025;86:1501-1503.
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  36. ABDALLA M, Makarem N
    Promoting Sleep Health to Prevent and Manage Systemic Hypertension.
    J Am Coll Cardiol. 2025;86:1498-1500.
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  37. KRUMHOLZ HM
    Severe Hypertension: The Next Never Event.
    J Am Coll Cardiol. 2025;86:1459-1461.
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  38. JONES DW, Ferdinand KC, Taler SJ, Johnson HM, et al
    2025 AHA/ACC/AANP/AAPA/ABC/ACCP/ACPM/AGS/AMA/ASPC/NMA/PCNA/SGIM Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Joint Commi
    J Am Coll Cardiol. 2025;86:1567-1678.
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    October 2025
  39. MCCARTHY CP, McEvoy JW, Brown JM
    PREVENTing Hypertensive Cardiovascular Disease: Where to Draw the Line?
    J Am Coll Cardiol. 2025;86:1449-1451.
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  40. DERINGTON CG, Berchie RO, Greene T, Jacobs JA, et al
    Using PREVENT Equations to Compare Intensive vs Standard Systolic Blood Pressure Control for Primary Prevention in SPRINT.
    J Am Coll Cardiol. 2025;86:1437-1448.
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  41. LI S, Peng Y, Li Y, Sun Y, et al
    Effects of Intensive Blood Pressure Control in Patients With Frailty: A Post Hoc Analysis From ESPRIT.
    J Am Coll Cardiol. 2025 Oct 15:S0735-1097(25)07783.
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  42. PACKER M, Butler J, Lam CSP, Zannad F, et al
    Central Adiposity or Hypertension: Which Drives Heart Failure With a Preserved Ejection Fraction?
    J Am Coll Cardiol. 2025 Oct 1:S0735-1097(25)07501.
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    September 2025
  43. ZEDER K, Maron BA
    To Anticoagulate or Not to Anticoagulate in Pulmonary Arterial Hypertension... That Is the Question!
    J Am Coll Cardiol. 2025;86:996-998.
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  44. BERTOLETTI L, Escal J, Boucly A, Turquier S, et al
    Association Between Anticoagulant Therapy and Survival in Pulmonary Arterial Hypertension: A Registry Report and Updated Meta-Analysis.
    J Am Coll Cardiol. 2025;86:982-995.
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  45. SONG Q, Peng X, Bai J, Yang R, et al
    Intensive Blood Pressure Control in Older Patients With Hypertension: 6-Year Results of the STEP Trial.
    J Am Coll Cardiol. 2025 Sep 8:S0735-1097(25)07023.
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    August 2025
  46. BRUGGE D, Eliasziw M, Thanikachalam M, Kuchhal V, et al
    Effect of HEPA Filtration Air Purifiers on Blood Pressure: A Pragmatic Randomized Crossover Trial.
    J Am Coll Cardiol. 2025;86:577-589.
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  47. KHAN SS, Lloyd-Jones DM, Abdalla M, Bello NA, et al
    Use of Risk Assessment to Guide Decision-Making for Blood Pressure Management in the Primary Prevention of Cardiovascular Disease: A Scientific Statement From the American Heart Association and American College of Cardiology.
    J Am Coll Cardiol. 2025 Aug 26:S0735-1097(25)07342.
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  48. LI J, Lei L, Li Y, Zhang H, et al
    Effect of Intensive Blood Pressure Control on Stroke: A Prespecified Secondary Analysis of the ESPRIT Trial.
    J Am Coll Cardiol. 2025 Aug 21:S0735-1097(25)07382.
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  49. YANG H, Lu Y
    Reply: Systolic Blood Pressure and All-Cause Mortality in Treated Hypertensive Adults Aged 80+ Years.
    J Am Coll Cardiol. 2025;86:e67-e68.
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  50. KOLLIAS A, Komnianou A, Kyriakoulis KG
    Systolic Blood Pressure and All-Cause Mortality in Treated Hypertensive Adults Aged 80+ Years.
    J Am Coll Cardiol. 2025;86:e65-e66.
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  51. JOYNT MADDOX KE, Emanuel EJ, Berenson RA
    Policy Agenda to Close the Hypertension Gap.
    J Am Coll Cardiol. 2025 Aug 15:S0735-1097(25)07396.
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  52. LU Y
    Why Can't We Get There?: Understanding Persistent Hypertension in Real-World Care.
    J Am Coll Cardiol. 2025 Aug 15:S0735-1097(25)07394.
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    July 2025
  53. HUANG X, Zhang H, Li Y, Ge J, et al
    Modest Effects of Intensive Blood Pressure-Lowering on Quality of Life in Patients at High Cardiovascular Risk: The ESPRIT trial.
    J Am Coll Cardiol. 2025 Jul 25:S0735-1097(25)06777.
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  54. WANG B, Shi D, Zhang Z, Zhang L, et al
    Effect of Intensive Blood Pressure Lowering Treatment on Retinal Microvasculature: Secondary Analysis From ESPRIT.
    J Am Coll Cardiol. 2025 Jul 25:S0735-1097(25)06500.
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    June 2025
  55. LANG IM, Brenot P, Bouvaist H, Fadel E, et al
    Balloon Pulmonary Angioplasty for Chronic Thromboembolic Pulmonary Hypertension: Results of an International Multicenter Prospective Registry.
    J Am Coll Cardiol. 2025;85:2270-2284.
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  56. MCCARTHY CP, McEvoy JW
    Reflections on Binary Thresholds for Hypercholesterolemia and Hypertension.
    J Am Coll Cardiol. 2025 Jun 3:S0735-1097(25)06472.
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    April 2025
  57. MATHEW V, Khan RR, Jowell AR, Yan Q, et al
    Genetic Risk and First-Trimester Cardiovascular Health Predict Hypertensive Disorders of Pregnancy in Nulliparous Women.
    J Am Coll Cardiol. 2025;85:1488-1500.
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  58. VAUGHAN LE, Garovic VD
    Reply: Social Work Interventions to Reduce Cardiovascular Risk in Women With Hypertensive Disorders of Pregnancy.
    J Am Coll Cardiol. 2025;85:e131.
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  59. ZHOU R, Ye S, Liu J, Duan L, et al
    Social Work Interventions to Reduce Cardiovascular Risk in Women With Hypertensive Disorders of Pregnancy.
    J Am Coll Cardiol. 2025;85:e129-e130.
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    February 2025
  60. YANG H, Huang C, Sawano M, Herrin J, et al
    Systolic Blood Pressure and Cardiovascular Mortality in U.S. Adults Aged 80+ Taking Antihypertensive Medications.
    J Am Coll Cardiol. 2025 Feb 26:S0735-1097(25)00335.
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    January 2025
  61. MESSERLI FH
    Renal Denervation: Antihypertensive Therapy or Gizmo Idolatry?
    J Am Coll Cardiol. 2025 Jan 9:S0735-1097(24)10485.
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    December 2024
  62. LU Y, Spatz ES, Krumholz HM
    Navigating the 2024 ESC Hypertension Guidelines: What Is New, Context, and Future Directions.
    J Am Coll Cardiol. 2024 Dec 30:S0735-1097(24)10475.
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    November 2024
  63. VAUGHAN LE, Kanaji Y, Suvakov S, Parashuram S, et al
    Hypertensive Disorders of Pregnancy Increase the Risk for Myocardial Infarction: A Population-Based Study.
    J Am Coll Cardiol. 2024 Nov 2:S0735-1097(24)09771.
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  64. HONIGBERG MC
    Classification of Myocardial Infarction in Women With Hypertensive Disorders of Pregnancy.
    J Am Coll Cardiol. 2024 Nov 1:S0735-1097(24)09773.
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    October 2024
  65. LANDSTEINER I, Ramesh A, Yang BQ, Lewis GD, et al
    Hemodynamic Insights From Provocative Testing in Pulmonary Hypertension and Heart Failure With Preserved Ejection Fraction.
    J Am Coll Cardiol. 2024 Oct 16:S0735-1097(24)09806.
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  66. REDDY YNV, Frantz RP, Hassoun PM, Hemnes AR, et al
    Clinical Implications of Pretest Probability of HFpEF on Outcomes in Precapillary Pulmonary Hypertension.
    J Am Coll Cardiol. 2024 Oct 15:S0735-1097(24)08392.
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    September 2024
  67. FARBER HW, Schoenberg NC
    Fucosylation: The Prognostic Impact of Sugar in Pulmonary Arterial Hypertension.
    J Am Coll Cardiol. 2024;84:1104-1106.
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  68. ZHANG ZJ, Liu C, Ma JL, Ma JS, et al
    Prognostic Value of Plasma Immunoglobulin G N-Glycome Traits in Pulmonary Arterial Hypertension.
    J Am Coll Cardiol. 2024;84:1092-1103.
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    August 2024
  69. RODGERS A, Salam A, Schutte AE, Cushman WC, et al
    Efficacy and Safety of a Novel Low-Dose Triple Single-Pill Combination Compared With Placebo for Initial Treatment of Hypertension.
    J Am Coll Cardiol. 2024 Aug 30:S0735-1097(24)08227.
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  70. ONUMA OK
    Treating Hypertension With a Single (Combination) Pill: Changing the Paradigm.
    J Am Coll Cardiol. 2024 Aug 22:S0735-1097(24)08253.
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    July 2024
  71. REA F, Corrao G, Mancia G
    Reply: Antihypertensive Drug Therapy and Dementia in the Elderly.
    J Am Coll Cardiol. 2024;84:e41.
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  72. KAWADA T
    Antihypertensive Drug Therapy and Dementia in the Elderly.
    J Am Coll Cardiol. 2024;84:e39.
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    May 2024
  73. OU YH, Colpani JT, Cheong CS, Loke W, et al
    Mandibular Advancement vs CPAP for Blood Pressure Reduction in Patients With Obstructive Sleep Apnea.
    J Am Coll Cardiol. 2024;83:1760-1772.
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    April 2024
  74. BOULESTREAU R, Spiewak M, Januszewicz A, Kreutz R, et al
    Malignant Hypertension:A Systemic Cardiovascular Disease: JACC Review Topic of the Week.
    J Am Coll Cardiol. 2024;83:1688-1701.
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  75. BEKHUIS Y, Verwerft J, Claessen G
    Exercise Echocardiography for mPAP/CO Slope Estimation: A New Standard for Routine Clinical Care?
    J Am Coll Cardiol. 2024;83:e141-e142.
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  76. WRIGHT CB, Egle M
    Rethinking Blood Pressure Treatment and Dementia Risk in Older Adults: Is Adherence the Holy Grail?
    J Am Coll Cardiol. 2024;83:1204-1206.
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  77. REA F, Corrao G, Mancia G
    Risk of Dementia During Antihypertensive Drug Therapy in the Elderly.
    J Am Coll Cardiol. 2024;83:1194-1203.
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    March 2024
  78. LOWERY MM, Hill NS, Wang L, Mehra R, et al
    Reply: Probing Sleep-Related Hypoxia's Impact on RV Dysfunction and PAH Survival: Uncertainties Clarified?
    J Am Coll Cardiol. 2024;83:e109.
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  79. HUANG Z, Duan A, Luo Q, Liu Z, et al
    Probing Sleep-Related Hypoxia's Impact on RV Dysfunction and PAH Survival: Uncertainties Clarified?
    J Am Coll Cardiol. 2024;83:e107.
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    February 2024
  80. OLDE ENGBERINK RHG
    Salt Intake: Reduce or Substitute?
    J Am Coll Cardiol. 2024;83:723-725.
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  81. ZHANG X, Yuan Y, Li C, Feng X, et al
    Effect of a Salt Substitute on Incidence of Hypertension and Hypotension Among Normotensive Adults.
    J Am Coll Cardiol. 2024;83:711-722.
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  82. HALL ME, Mace HP, Hall JE
    Bariatric Surgery for Obesity Hypertension: A Gateway for Durable Blood Pressure Control.
    J Am Coll Cardiol. 2024;83:649-651.
    >> Share

  83. SCHIAVON CA, Cavalcanti AB, Oliveira JD, Machado RHV, et al
    Randomized Trial of Effect of Bariatric Surgery on Blood Pressure After 5 Years.
    J Am Coll Cardiol. 2024;83:637-648.
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    January 2024
  84. WESSELS JN, Bogaard HJ
    Double Down on Single-Tablet Combination Therapy in Pulmonary Arterial Hypertension: Possible Benefits for Selected Patients.
    J Am Coll Cardiol. 2024;83:485-487.
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  85. GRUNIG E, Jansa P, Fan F, Hauser JA, et al
    Randomized Trial of Macitentan/Tadalafil Single-Tablet Combination Therapy for Pulmonary Arterial Hypertension.
    J Am Coll Cardiol. 2024;83:473-484.
    >> Share

    November 2023
  86. JAVAHERI S, Somers VK
    Sleep, Hypoxia, and Survival in Group 1 Pulmonary Arterial Hypertension: What to Do?
    J Am Coll Cardiol. 2023;82:2006-2008.
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  87. LOWERY MM, Hill NS, Wang L, Rosenzweig EB, et al
    Sleep-Related Hypoxia, Right Ventricular Dysfunction, and Survival in Patients With Group 1 Pulmonary Arterial Hypertension.
    J Am Coll Cardiol. 2023;82:1989-2005.
    >> Share

  88. MATHIAS W JR, Le Bihan DCS, Hajjar LA
    Stress Echocardiography: Another Hilltop, and It Is Better Than Ever.
    J Am Coll Cardiol. 2023;82:1986-1988.
    >> Share

  89. GARGANI L, Pugliese NR, De Biase N, Mazzola M, et al
    Exercise Stress Echocardiography of the Right Ventricle and Pulmonary Circulation.
    J Am Coll Cardiol. 2023;82:1973-1985.
    >> Share

  90. VINAYAK M, Olin JW, Stone GW
    The Ongoing Odyssey of Renal Denervation.
    J Am Coll Cardiol. 2023;82:1824-1827.
    >> Share

  91. KANDZARI DE, Townsend RR, Kario K, Mahfoud F, et al
    Safety and Efficacy of Renal Denervation in Patients Taking Antihypertensive Medications.
    J Am Coll Cardiol. 2023;82:1809-1823.
    >> Share

    September 2023
  92. MORAN AE, Gupta R
    Implementation of Global Hearts Hypertension Control Programs in 32 Low- and Middle-Income Countries: JACC International.
    J Am Coll Cardiol. 2023 Sep 19:S0735-1097(23)06633.
    >> Share


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