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Articles published in
Proc Natl Acad Sci U S A
    December 2025
  1. CAIL RC, Barua B, Baez-Cruz FA, Winkelmann DA, et al
    A myosin hypertrophic cardiomyopathy mutation disrupts the super-relaxed state and boosts contractility by enhanced actin attachment.
    Proc Natl Acad Sci U S A. 2025;122:e2521561122.
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    September 2025
  2. PERLA S, Stiegler AL, Yi JS, Enyenihi L, et al
    SHP2 genetic variants in NSML-associated RASopathies disrupt the PZR-IRX transcription factor signaling axis.
    Proc Natl Acad Sci U S A. 2025;122:e2503631122.
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    July 2025
  3. CROSBY GS, Hei B, Lynn ML, Chakraborti A, et al
    Resolving the structure and dynamics of the disordered C terminus of human cardiac troponin T and effects of cardiomyopathic mutations.
    Proc Natl Acad Sci U S A. 2025;122:e2425343122.
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  4. CAO T, Feng HZ, Jayasundar JJ, Jin JP, et al
    The highly conserved C-terminal end segment of troponin T binds tropomyosin and actin to function in modulating contractile kinetics.
    Proc Natl Acad Sci U S A. 2025;122:e2507107122.
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    May 2024
  5. LEE S, Vander Roest AS, Blair CA, Kao K, et al
    Incomplete-penetrant hypertrophic cardiomyopathy MYH7 G256E mutation causes hypercontractility and elevated mitochondrial respiration.
    Proc Natl Acad Sci U S A. 2024;121:e2318413121.
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