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Herpes simplex Infection

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Articles published in
PLoS Pathog
    August 2025
  1. ROBERTS APE, Orr A, Iliev V, Orr L, et al
    Daxx mediated histone H3.3 deposition on HSV-1 DNA restricts genome decompaction and the progression of immediate-early transcription.
    PLoS Pathog. 2025;21:e1012501.
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    May 2025
  2. ARSHAD S, Rana H, Truong NR, Pattamatta U, et al
    Herpes simplex virus type-1 infection and spread in a novel porcine corneal explant model is restricted to the epithelium.
    PLoS Pathog. 2025;21:e1013162.
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  3. ALBANO C, Trifiro L, Hewelt-Belka W, Cairns DM, et al
    The impact of fatty acid synthase on HSV-1 infection dynamics.
    PLoS Pathog. 2025;21:e1013068.
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    April 2025
  4. PARCHURE A, Cesarec M, Braut A, Kolman R, et al
    ADAR1 p150 prevents HSV-1 from triggering PKR/eIF2alpha-mediated translational arrest and is required for efficient viral replication.
    PLoS Pathog. 2025;21:e1012452.
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    February 2025
  5. DUTTON AJ, Turnbaugh EM, Patel CD, Garland CR, et al
    Asymptomatic neonatal herpes simplex virus infection in mice leads to persistent CNS infection and long-term cognitive impairment.
    PLoS Pathog. 2025;21:e1012935.
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    October 2024
  6. WANG S, Jaggi U, Katsumata M, Ghiasi H, et al
    The importance of IFNalpha2A (Roferon-A) in HSV-1 latency and T cell exhaustion in ocularly infected mice.
    PLoS Pathog. 2024;20:e1012612.
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  7. SINGH P, Zhu L, Shipley MA, Ye ZA, et al
    The HSV-1 encoded CCCTC-binding factor, CTRL2, impacts the nature of viral chromatin during HSV-1 lytic infection.
    PLoS Pathog. 2024;20:e1012621.
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    September 2024
  8. WANG K, Jordan T, Dowdell K, Herbert R, et al
    A nonhuman primate model for genital herpes simplex virus 2 infection that results in vaginal vesicular lesions, virus shedding, and seroconversion.
    PLoS Pathog. 2024;20:e1012477.
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    June 2024
  9. RANA H, Truong NR, Johnson B, Baharlou H, et al
    Herpes simplex virus spreads rapidly in human foreskin, partly driven by chemokine-induced redistribution of Nectin-1 on keratinocytes.
    PLoS Pathog. 2024;20:e1012267.
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  10. YANG C, Wang CY, Long QY, Cao Z, et al
    The roles of nuclear orphan receptor NR2F6 in anti-viral innate immunity.
    PLoS Pathog. 2024;20:e1012271.
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    April 2024
  11. LECLERC S, Gupta A, Ruokolainen V, Chen JH, et al
    Progression of herpesvirus infection remodels mitochondrial organization and metabolism.
    PLoS Pathog. 2024;20:e1011829.
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    December 2023
  12. THOMAS ECM, Finnen RL, Mewburn JD, Archer SL, et al
    The Herpes Simplex Virus pUL16 and pUL21 Proteins Prevent Capsids from Docking at Nuclear Pore Complexes.
    PLoS Pathog. 2023;19:e1011832.
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  13. PASQUERO S, Gugliesi F, Biolatti M, Dell'Oste V, et al
    Citrullination profile analysis reveals peptidylarginine deaminase 3 as an HSV-1 target to dampen the activity of candidate antiviral restriction factors.
    PLoS Pathog. 2023;19:e1011849.
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    July 2023
  14. PACKARD JE, Williams MR, Fromuth DP, Dembowski JA, et al
    Proliferating cell nuclear antigen inhibitors block distinct stages of herpes simplex virus infection.
    PLoS Pathog. 2023;19:e1011539.
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  15. FU Y, Zhan X, You X, Nie D, et al
    USP12 promotes antiviral responses by deubiquitinating and stabilizing IFI16.
    PLoS Pathog. 2023;19:e1011480.
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  16. XUE Q, Zhu Z, Xue Z, Yang F, et al
    NOG1 downregulates type I interferon production by targeting phosphorylated interferon regulatory factor 3.
    PLoS Pathog. 2023;19:e1011511.
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    June 2023
  17. PHEASANT K, Perry D, Wise EL, Cheng V, et al
    Dysregulated metabolism of the late herpes simplex virus 1 transcriptome through the vhs-VP22 axis uncouples virus cytopathic effect and virus production.
    PLoS Pathog. 2023;19:e1010966.
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