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Herpes simplex Infection
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Articles published in
PLoS Pathog
    December 2023
  1. THOMAS ECM, Finnen RL, Mewburn JD, Archer SL, et al
    The Herpes Simplex Virus pUL16 and pUL21 Proteins Prevent Capsids from Docking at Nuclear Pore Complexes.
    PLoS Pathog. 2023;19:e1011832.
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  2. PASQUERO S, Gugliesi F, Biolatti M, Dell'Oste V, et al
    Citrullination profile analysis reveals peptidylarginine deaminase 3 as an HSV-1 target to dampen the activity of candidate antiviral restriction factors.
    PLoS Pathog. 2023;19:e1011849.
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    July 2023
  3. PACKARD JE, Williams MR, Fromuth DP, Dembowski JA, et al
    Proliferating cell nuclear antigen inhibitors block distinct stages of herpes simplex virus infection.
    PLoS Pathog. 2023;19:e1011539.
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  4. FU Y, Zhan X, You X, Nie D, et al
    USP12 promotes antiviral responses by deubiquitinating and stabilizing IFI16.
    PLoS Pathog. 2023;19:e1011480.
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  5. XUE Q, Zhu Z, Xue Z, Yang F, et al
    NOG1 downregulates type I interferon production by targeting phosphorylated interferon regulatory factor 3.
    PLoS Pathog. 2023;19:e1011511.
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    June 2023
  6. PHEASANT K, Perry D, Wise EL, Cheng V, et al
    Dysregulated metabolism of the late herpes simplex virus 1 transcriptome through the vhs-VP22 axis uncouples virus cytopathic effect and virus production.
    PLoS Pathog. 2023;19:e1010966.
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    November 2022
  7. THOMAS ECM, Bossert M, Banfield BW
    The herpes simplex virus tegument protein pUL21 is required for viral genome retention within capsids.
    PLoS Pathog. 2022;18:e1010969.
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    October 2022
  8. WANG S, Jaggi U, Ghiasi H
    Knockout of signal peptide peptidase in the eye reduces HSV-1 replication and eye disease in ocularly infected mice.
    PLoS Pathog. 2022;18:e1010898.
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    September 2022
  9. GUO H, Koehler HS, Mocarski ES, Dix RD, et al
    RIPK3 and caspase 8 collaborate to limit herpes simplex encephalitis.
    PLoS Pathog. 2022;18:e1010857.
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    August 2022
  10. WANG LC, Wu SR, Yao HW, Ling P, et al
    Suppression of annexin A1 and its receptor reduces herpes simplex virus 1 lethality in mice.
    PLoS Pathog. 2022;18:e1010692.
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    July 2022
  11. KALKE K, Lund LM, Nyman MC, Levanova AA, et al
    Swarms of chemically modified antiviral siRNA targeting herpes simplex virus infection in human corneal epithelial cells.
    PLoS Pathog. 2022;18:e1010688.
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  12. NAHAS KL, Connor V, Scherer KM, Kaminski CF, et al
    Near-native state imaging by cryo-soft-X-ray tomography reveals remodelling of multiple cellular organelles during HSV-1 infection.
    PLoS Pathog. 2022;18:e1010629.
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    June 2022
  13. PATAKI Z, Sanders EK, Heldwein EE
    A surface pocket in the cytoplasmic domain of the herpes simplex virus fusogen gB controls membrane fusion.
    PLoS Pathog. 2022;18:e1010435.
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  14. WHITFORD AL, Cliffe AR
    Key questions on the epigenetics of herpes simplex virus latency.
    PLoS Pathog. 2022;18:e1010587.
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    May 2022
  15. RATHBUN MM, Shipley MM, Bowen CD, Selke S, et al
    Comparison of herpes simplex virus 1 genomic diversity between adult sexual transmission partners with genital infection.
    PLoS Pathog. 2022;18:e1010437.
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    February 2022
  16. YANG X, Xiang Z, Sun Z, Ji F, et al
    Host MOV10 is induced to restrict herpes simplex virus 1 lytic infection by promoting type I interferon response.
    PLoS Pathog. 2022;18:e1010301.
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    January 2022
  17. DANASTAS K, Larsen A, Jobson S, Guo G, et al
    Herpes simplex virus-1 utilizes the host actin cytoskeleton for its release from axonal growth cones.
    PLoS Pathog. 2022;18:e1010264.
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  18. BENEDYK TH, Muenzner J, Connor V, Han Y, et al
    Correction: pUL21 is a viral phosphatase adaptor that promotes herpes simplex virus replication and spread.
    PLoS Pathog. 2022;18:e1010225.
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  19. WANG S, Jaggi U, Tormanen K, Hirose S, et al
    Absence of signal peptide peptidase in peripheral sensory neurons affects latency-reactivation in HSV-1 ocularly infected mice.
    PLoS Pathog. 2022;18:e1010281.
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    December 2021
  20. AHO V, Salminen S, Mattola S, Gupta A, et al
    Infection-induced chromatin modifications facilitate translocation of herpes simplex virus capsids to the inner nuclear membrane.
    PLoS Pathog. 2021;17:e1010132.
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    November 2021
  21. DELVA JL, Van Waesberghe C, Klupp BG, Mettenleiter TC, et al
    Alphaherpesvirus-induced activation of plasmacytoid dendritic cells depends on the viral glycoprotein gD and is inhibited by non-infectious light particles.
    PLoS Pathog. 2021;17:e1010117.
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    October 2021
  22. JAGGI U, Matundan HH, Yu J, Hirose S, et al
    Essential role of M1 macrophages in blocking cytokine storm and pathology associated with murine HSV-1 infection.
    PLoS Pathog. 2021;17:e1009999.
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    September 2021
  23. SHARMA N, Wang C, Kessler P, Sen GC, et al
    Herpes simplex virus 1 evades cellular antiviral response by inducing microRNA-24, which attenuates STING synthesis.
    PLoS Pathog. 2021;17:e1009950.
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  24. KITE J, Russell T, Jones J, Elliott G, et al
    Cell-to-cell transmission of HSV1 in human keratinocytes in the absence of the major entry receptor, nectin1.
    PLoS Pathog. 2021;17:e1009631.
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    August 2021
  25. BENEDYK TH, Muenzner J, Connor V, Han Y, et al
    pUL21 is a viral phosphatase adaptor that promotes herpes simplex virus replication and spread.
    PLoS Pathog. 2021;17:e1009824.
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  26. LOPEZ-MUNOZ AD, Rastrojo A, Martin R, Alcami A, et al
    Herpes simplex virus 2 (HSV-2) evolves faster in cell culture than HSV-1 by generating greater genetic diversity.
    PLoS Pathog. 2021;17:e1009541.
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  27. MURADOV JH, Finnen RL, Gulak MA, Hay TJM, et al
    pUL21 regulation of pUs3 kinase activity influences the nature of nuclear envelope deformation by the HSV-2 nuclear egress complex.
    PLoS Pathog. 2021;17:e1009679.
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  28. WANG S, Jaggi U, Yu J, Ghiasi H, et al
    Blocking HSV-1 glycoprotein K binding to signal peptide peptidase reduces virus infectivity in vitro and in vivo.
    PLoS Pathog. 2021;17:e1009848.
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    June 2021
  29. MEIER AF, Tobler K, Leisi R, Lkharrazi A, et al
    Herpes simplex virus co-infection facilitates rolling circle replication of the adeno-associated virus genome.
    PLoS Pathog. 2021;17:e1009638.
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    April 2021
  30. SHAPIRO M, Krug LT, MacCarthy T
    Mutational pressure by host APOBEC3s more strongly affects genes expressed early in the lytic phase of herpes simplex virus-1 (HSV-1) and human polyomavirus (HPyV) infection.
    PLoS Pathog. 2021;17:e1009560.
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  31. BERTRAM KM, Truong NR, Smith JB, Kim M, et al
    Herpes Simplex Virus type 1 infects Langerhans cells and the novel epidermal dendritic cell, Epi-cDC2s, via different entry pathways.
    PLoS Pathog. 2021;17:e1009536.
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  32. CABRAL JM, Cushman CH, Sodroski CN, Knipe DM, et al
    ATRX limits the accessibility of histone H3-occupied HSV genomes during lytic infection.
    PLoS Pathog. 2021;17:e1009567.
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    March 2021
  33. LIU X, Ma Y, Voss K, van Gent M, et al
    The herpesvirus accessory protein gamma134.5 facilitates viral replication by disabling mitochondrial translocation of RIG-I.
    PLoS Pathog. 2021;17:e1009446.
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  34. MANGOLD CA, Rathbun MM, Renner DW, Kuny CV, et al
    Viral infection of human neurons triggers strain-specific differences in host neuronal and viral transcriptomes.
    PLoS Pathog. 2021;17:e1009441.
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    February 2021
  35. HAYES CK, Wilcox DR, Yang Y, Coleman GK, et al
    ASC-dependent inflammasomes contribute to immunopathology and mortality in herpes simplex encephalitis.
    PLoS Pathog. 2021;17:e1009285.
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  36. REDDI TS, Merkl PE, Lim SY, Letvin NL, et al
    Tripartite Motif 22 (TRIM22) protein restricts herpes simplex virus 1 by epigenetic silencing of viral immediate-early genes.
    PLoS Pathog. 2021;17:e1009281.
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    December 2020
  37. VANNI EAH, Foley JW, Davison AJ, Sommer M, et al
    The latency-associated transcript locus of herpes simplex virus 1 is a virulence determinant in human skin.
    PLoS Pathog. 2020;16:e1009166.
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  38. DUCROUX A, Benhenda S, Riviere L, Semmes OJ, et al
    Correction: The Tudor Domain Protein Spindlin1 Is Involved in Intrinsic Antiviral Defense against Incoming Hepatitis B Virus and Herpes Simplex Virus Type 1.
    PLoS Pathog. 2020;16:e1009135.
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    October 2020
  39. QIAO H, Guo M, Shang J, Zhao W, et al
    Herpes simplex virus type 1 infection leads to neurodevelopmental disorder-associated neuropathological changes.
    PLoS Pathog. 2020;16:e1008899.
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  40. JAGGI U, Yang M, Matundan HH, Hirose S, et al
    Increased phagocytosis in the presence of enhanced M2-like macrophage responses correlates with increased primary and latent HSV-1 infection.
    PLoS Pathog. 2020;16:e1008971.
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    August 2020
  41. XU X, Feng X, Wang L, Yi T, et al
    A HSV1 mutant leads to an attenuated phenotype and induces immunity with a protective effect.
    PLoS Pathog. 2020;16:e1008703.
    >> Share


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