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HIV Infection

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Articles published in
PLoS Pathog
    February 2021
  1. HSU DC, Schuetz A, Imerbsin R, Silsorn D, et al
    TLR7 agonist, N6-LS and PGT121 delayed viral rebound in SHIV-infected macaques after antiretroviral therapy interruption.
    PLoS Pathog. 2021;17:e1009339.
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  2. GAO Y, He S, Tian W, Li D, et al
    First complete-genome documentation of HIV-1 intersubtype superinfection with transmissions of diverse recombinants over time to five recipients.
    PLoS Pathog. 2021;17:e1009258.
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  3. CHARLES TP, Burton SL, Arunachalam PS, Cottrell CA, et al
    The C3/465 glycan hole cluster in BG505 HIV-1 envelope is the major neutralizing target involved in preventing mucosal SHIV infection.
    PLoS Pathog. 2021;17:e1009257.
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  4. RENNER N, Mallery DL, Faysal KMR, Peng W, et al
    A lysine ring in HIV capsid pores coordinates IP6 to drive mature capsid assembly.
    PLoS Pathog. 2021;17:e1009164.
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  5. DINKELE R, Gessner S, McKerry A, Leonard B, et al
    Capture and visualization of live Mycobacterium tuberculosis bacilli from tuberculosis patient bioaerosols.
    PLoS Pathog. 2021;17:e1009262.
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    January 2021
  6. SOWD GA, Aiken C
    Inositol phosphates promote HIV-1 assembly and maturation to facilitate viral spread in human CD4+ T cells.
    PLoS Pathog. 2021;17:e1009190.
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  7. BACCHUS-SOUFFAN C, Fitch M, Symons J, Abdel-Mohsen M, et al
    Relationship between CD4 T cell turnover, cellular differentiation and HIV persistence during ART.
    PLoS Pathog. 2021;17:e1009214.
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  8. CARLIN E, Greer B, Lowman K, Duverger A, et al
    Extensive proteomic and transcriptomic changes quench the TCR/CD3 activation signal of latently HIV-1 infected T cells.
    PLoS Pathog. 2021;17:e1008748.
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  9. SANTIAGO JC, Goldman JD, Zhao H, Pankow AP, et al
    Intra-host changes in Kaposi sarcoma-associated herpesvirus genomes in Ugandan adults with Kaposi sarcoma.
    PLoS Pathog. 2021;17:e1008594.
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  10. SHRESTHA P, Davis DA, Jaeger HK, Stream A, et al
    Pomalidomide restores immune recognition of primary effusion lymphoma through upregulation of ICAM-1 and B7-2.
    PLoS Pathog. 2021;17:e1009091.
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    December 2020
  11. AKAHOSHI T, Gatanaga H, Kuse N, Chikata T, et al
    T-cell responses to sequentially emerging viral escape mutants shape long-term HIV-1 population dynamics.
    PLoS Pathog. 2020;16:e1009177.
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  12. UPADHYAY C, Feyznezhad R, Cao L, Chan KW, et al
    Signal peptide of HIV-1 envelope modulates glycosylation impacting exposure of V1V2 and other epitopes.
    PLoS Pathog. 2020;16:e1009185.
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  13. NOEL-ROMAS L, Perner M, Molatlhegi R, Farr Zuend C, et al
    Vaginal microbiome-hormonal contraceptive interactions associate with the mucosal proteome and HIV acquisition.
    PLoS Pathog. 2020;16:e1009097.
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  14. WINANS S, Goff SP
    Mutations altering acetylated residues in the CTD of HIV-1 integrase cause defects in proviral transcription at early times after integration of viral DNA.
    PLoS Pathog. 2020;16:e1009147.
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  15. KHAMASSI M, Xu L, Rey J, Duchemin M, et al
    The CH1alpha domain of mucosal gp41 IgA contributes to antibody specificity and antiviral functions in HIV-1 highly exposed Sero-Negative individuals.
    PLoS Pathog. 2020;16:e1009103.
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  16. MDLULI T, Jian N, Slike B, Paquin-Proulx D, et al
    RV144 HIV-1 vaccination impacts post-infection antibody responses.
    PLoS Pathog. 2020;16:e1009101.
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  17. WU NC, Yuan M, Bangaru S, Huang D, et al
    A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody.
    PLoS Pathog. 2020;16:e1009089.
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  18. LI Z, Hajian C, Greene WC
    Identification of unrecognized host factors promoting HIV-1 latency.
    PLoS Pathog. 2020;16:e1009055.
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  19. CHEU RK, Gustin AT, Lee C, Schifanella L, et al
    Impact of vaginal microbiome communities on HIV antiretroviral-based pre-exposure prophylaxis (PrEP) drug metabolism.
    PLoS Pathog. 2020;16:e1009024.
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    November 2020
  20. MORON-LOPEZ S, Telwatte S, Sarabia I, Battivelli E, et al
    Human splice factors contribute to latent HIV infection in primary cell models and blood CD4+ T cells from ART-treated individuals.
    PLoS Pathog. 2020;16:e1009060.
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  21. GODOT V, Tcherakian C, Gil L, Cervera-Marzal I, et al
    TLR-9 agonist and CD40-targeting vaccination induces HIV-1 envelope-specific B cells with a diversified immunoglobulin repertoire in humanized mice.
    PLoS Pathog. 2020;16:e1009025.
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  22. TAHER H, Mahyari E, Kreklywich C, Uebelhoer LS, et al
    In vitro and in vivo characterization of a recombinant rhesus cytomegalovirus containing a complete genome.
    PLoS Pathog. 2020;16:e1008666.
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  23. GELBART M, Harari S, Ben-Ari Y, Kustin T, et al
    Drivers of within-host genetic diversity in acute infections of viruses.
    PLoS Pathog. 2020;16:e1009029.
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  24. GOSWAMI R, Berendam SJ, Li SH, Nelson AN, et al
    Harnessing early life immunity to develop a pediatric HIV vaccine that can protect through adolescence.
    PLoS Pathog. 2020;16:e1008983.
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  25. CARTER JJ, Gardner JM, Poling BP, Welch MM, et al
    Transcriptional analysis of immune response genes during pathogenesis of cytomegalovirus retinitis in mice with murine acquired immunodeficiency syndrome.
    PLoS Pathog. 2020;16:e1009032.
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    October 2020
  26. TRYPSTEEN W, Van Cleemput J, Snippenberg WV, Gerlo S, et al
    On the whereabouts of SARS-CoV-2 in the human body: A systematic review.
    PLoS Pathog. 2020;16:e1009037.
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  27. BRICKER KM, Obregon-Perko V, Uddin F, Williams B, et al
    Therapeutic vaccination of SIV-infected, ART-treated infant rhesus macaques using Ad48/MVA in combination with TLR-7 stimulation.
    PLoS Pathog. 2020;16:e1008954.
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  28. FRENCH AJ, Natesampillai S, Krogman A, Correia C, et al
    Reactivating latent HIV with PKC agonists induces resistance to apoptosis and is associated with phosphorylation and activation of BCL2.
    PLoS Pathog. 2020;16:e1008906.
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  29. GUO K, Shen G, Kibbie J, Gonzalez T, et al
    Qualitative Differences Between the IFNalpha subtypes and IFNbeta Influence Chronic Mucosal HIV-1 Pathogenesis.
    PLoS Pathog. 2020;16:e1008986.
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  30. SAHA B, Chisholm D, Kell AM, Mandell MA, et al
    A non-canonical role for the autophagy machinery in anti-retroviral signaling mediated by TRIM5alpha.
    PLoS Pathog. 2020;16:e1009017.
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  31. BOWMAN ER, Cameron CM, Richardson B, Kulkarni M, et al
    Macrophage maturation from blood monocytes is altered in people with HIV, and is linked to serum lipid profiles and activation indices: A model for studying atherogenic mechanisms.
    PLoS Pathog. 2020;16:e1008869.
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  32. GENOULA M, Marin Franco JL, Maio M, Dolotowicz B, et al
    Fatty acid oxidation of alternatively activated macrophages prevents foam cell formation, but Mycobacterium tuberculosis counteracts this process via HIF-1alpha activation.
    PLoS Pathog. 2020;16:e1008929.
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  33. DAS J, Devadhasan A, Linde C, Broge T, et al
    Mining for humoral correlates of HIV control and latent reservoir size.
    PLoS Pathog. 2020;16:e1008868.
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    September 2020
  34. PANIGRAHI S, Chen B, Fang M, Potashnikova D, et al
    CX3CL1 and IL-15 Promote CD8 T cell chemoattraction in HIV and in atherosclerosis.
    PLoS Pathog. 2020;16:e1008885.
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  35. KRASNOPOLSKY S, Kuzmina A, Taube R
    Genome-wide CRISPR knockout screen identifies ZNF304 as a silencer of HIV transcription that promotes viral latency.
    PLoS Pathog. 2020;16:e1008834.
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  36. ZANONI M, Palesch D, Pinacchio C, Statzu M, et al
    Innate, non-cytolytic CD8+ T cell-mediated suppression of HIV replication by MHC-independent inhibition of virus transcription.
    PLoS Pathog. 2020;16:e1008821.
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  37. JIN SW, Mwimanzi FM, Mann JK, Bwana MB, et al
    Variation in HIV-1 Nef function within and among viral subtypes reveals genetically separable antagonism of SERINC3 and SERINC5.
    PLoS Pathog. 2020;16:e1008813.
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  38. SINGH KP, Zerbato JM, Zhao W, Braat S, et al
    Intrahepatic CXCL10 is strongly associated with liver fibrosis in HIV-Hepatitis B co-infection.
    PLoS Pathog. 2020;16:e1008744.
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  39. MACHARIA GN, Yue L, Staller E, Dilernia D, et al
    Infection with multiple HIV-1 founder variants is associated with lower viral replicative capacity, faster CD4+ T cell decline and increased immune activation during acute infection.
    PLoS Pathog. 2020;16:e1008853.
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  40. OM K, Paquin-Proulx D, Montero M, Peachman K, et al
    Adjuvanted HIV-1 vaccine promotes antibody-dependent phagocytic responses and protects against heterologous SHIV challenge.
    PLoS Pathog. 2020;16:e1008764.
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  41. SCHRIJVERS R, Rijck J, Demeulemeester J, Adachi N, et al
    Correction: LEDGF/p75-Independent HIV-1 Replication Demonstrates a Role for HRP-2 and Remains Sensitive to Inhibition by LEDGINs.
    PLoS Pathog. 2020;16:e1008894.
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  42. NAKANO Y, Yamamoto K, Ueda MT, Soper A, et al
    A role for gorilla APOBEC3G in shaping lentivirus evolution including transmission to humans.
    PLoS Pathog. 2020;16:e1008812.
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  43. LOPEZ ANGEL CJ, Tomaras GD
    Bringing the path toward an HIV-1 vaccine into focus.
    PLoS Pathog. 2020;16:e1008663.
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    August 2020
  44. COTTRELL CA, van Schooten J, Bowman CA, Yuan M, et al
    Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates.
    PLoS Pathog. 2020;16:e1008753.
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  45. AAMER HA, McClure J, Ko D, Maenza J, et al
    Cells producing residual viremia during antiretroviral treatment appear to contribute to rebound viremia following interruption of treatment.
    PLoS Pathog. 2020;16:e1008791.
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  46. POULAIN F, Lejeune N, Willemart K, Gillet NA, et al
    Footprint of the host restriction factors APOBEC3 on the genome of human viruses.
    PLoS Pathog. 2020;16:e1008718.
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  47. RICANA CL, Lyddon TD, Dick RA, Johnson MC, et al
    Primate lentiviruses require Inositol hexakisphosphate (IP6) or inositol pentakisphosphate (IP5) for the production of viral particles.
    PLoS Pathog. 2020;16:e1008646.
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  48. BOSSO M, Prelli Bozzo C, Hotter D, Volcic M, et al
    Nuclear PYHIN proteins target the host transcription factor Sp1 thereby restricting HIV-1 in human macrophages and CD4+ T cells.
    PLoS Pathog. 2020;16:e1008752.
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  49. ELAHI S, Shahbaz S, Houston S
    Selective Upregulation of CTLA-4 on CD8+ T Cells Restricted by HLA-B*35Px Renders them to an Exhausted Phenotype in HIV-1 infection.
    PLoS Pathog. 2020;16:e1008696.
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  50. ORIOL-TORDERA B, Berdasco M, Llano A, Mothe B, et al
    Methylation regulation of Antiviral host factors, Interferon Stimulated Genes (ISGs) and T-cell responses associated with natural HIV control.
    PLoS Pathog. 2020;16:e1008678.
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  51. RESOP RS, Fromentin R, Newman D, Rigsby H, et al
    Fingolimod inhibits multiple stages of the HIV-1 life cycle.
    PLoS Pathog. 2020;16:e1008679.
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  52. ANTANASIJEVIC A, Ueda G, Brouwer PJM, Copps J, et al
    Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens.
    PLoS Pathog. 2020;16:e1008665.
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  53. PATERSON MJ, Caldera JR, Nguyen C, Sharma P, et al
    Harnessing antifungal immunity in pursuit of a Staphylococcus aureus vaccine strategy.
    PLoS Pathog. 2020;16:e1008733.
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    July 2020
  54. DIEDRICH CR, Rutledge T, Maiello P, Baranowski TM, et al
    SIV and Mycobacterium tuberculosis synergy within the granuloma accelerates the reactivation pattern of latent tuberculosis.
    PLoS Pathog. 2020;16:e1008413.
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  55. LIDENGE SJ, Kossenkov AV, Tso FY, Wickramasinghe J, et al
    Comparative transcriptome analysis of endemic and epidemic Kaposi's sarcoma (KS) lesions and the secondary role of HIV-1 in KS pathogenesis.
    PLoS Pathog. 2020;16:e1008681.
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    June 2020
  56. ILLINGWORTH CJR, Raghwani J, Serwadda D, Sewankambo NK, et al
    A de novo approach to inferring within-host fitness effects during untreated HIV-1 infection.
    PLoS Pathog. 2020;16:e1008171.
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  57. BROOKS K, Jones BR, Dilernia DA, Wilkins DJ, et al
    HIV-1 variants are archived throughout infection and persist in the reservoir.
    PLoS Pathog. 2020;16:e1008378.
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  58. SILVA-ARRIETA S, Goulder PJR, Brander C
    In silico veritas? Potential limitations for SARS-CoV-2 vaccine development based on T-cell epitope prediction.
    PLoS Pathog. 2020;16:e1008607.
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  59. HAPPEL AU, Kullin B, Gamieldien H, Wentzel N, et al
    Exploring potential of vaginal Lactobacillus isolates from South African women for enhancing treatment for bacterial vaginosis.
    PLoS Pathog. 2020;16:e1008559.
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  60. LUTGEN V, Narasipura SD, Barbian HJ, Richards M, et al
    HIV infects astrocytes in vivo and egresses from the brain to the periphery.
    PLoS Pathog. 2020;16:e1008381.
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  61. LEVY Y, Lacabaratz C, Ellefsen-Lavoie K, Stohr W, et al
    Optimal priming of poxvirus vector (NYVAC)-based HIV vaccine regimens for T cell responses requires three DNA injections. Results of the randomized multicentre EV03/ANRS VAC20 Phase I/II Trial.
    PLoS Pathog. 2020;16:e1008522.
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    May 2020
  62. ELLIS AL, Balgeman AJ, Larson EC, Rodgers MA, et al
    MAIT cells are functionally impaired in a Mauritian cynomolgus macaque model of SIV and Mtb co-infection.
    PLoS Pathog. 2020;16:e1008585.
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  63. JOSHI VR, Newman RM, Pack ML, Power KA, et al
    Gp41-targeted antibodies restore infectivity of a fusion-deficient HIV-1 envelope glycoprotein.
    PLoS Pathog. 2020;16:e1008577.
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  64. NACHER M, Couppie P, Epelboin L, Djossou F, et al
    Disseminated Histoplasmosis: Fighting a neglected killer of patients with advanced HIV disease in Latin America.
    PLoS Pathog. 2020;16:e1008449.
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    April 2020
  65. SANTER DM, Minty GES, Golec DP, Lu J, et al
    Differential expression of interferon-lambda receptor 1 splice variants determines the magnitude of the antiviral response induced by interferon-lambda 3 in human immune cells.
    PLoS Pathog. 2020;16:e1008515.
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  66. OHAINLE M, Kim K, Komurlu Keceli S, Felton A, et al
    TRIM34 restricts HIV-1 and SIV capsids in a TRIM5alpha-dependent manner.
    PLoS Pathog. 2020;16:e1008507.
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  67. HSIAO F, Frouard J, Gramatica A, Xie G, et al
    Tissue memory CD4+ T cells expressing IL-7 receptor-alpha (CD127) preferentially support latent HIV-1 infection.
    PLoS Pathog. 2020;16:e1008450.
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  68. SCHIFANELLA L, Barnett SW, Bissa M, Galli V, et al
    Correction: ALVAC-HIV B/C candidate HIV vaccine efficacy dependent on neutralization profile of challenge virus and adjuvant dose and type.
    PLoS Pathog. 2020;16:e1008531.
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  69. TAVAKOLI-TAMEH A, Janaka SK, Zarbock K, O'Connor S, et al
    Loss of tetherin antagonism by Nef impairs SIV replication during acute infection of rhesus macaques.
    PLoS Pathog. 2020;16:e1008487.
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    March 2020
  70. BOUCAU J, Das J, Joshi N, Le Gall S, et al
    Latency reversal agents modulate HIV antigen processing and presentation to CD8 T cells.
    PLoS Pathog. 2020;16:e1008442.
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  71. KONG W, Biswas A, Zhou D, Fiches G, et al
    Nucleolar protein NOP2/NSUN1 suppresses HIV-1 transcription and promotes viral latency by competing with Tat for TAR binding and methylation.
    PLoS Pathog. 2020;16:e1008430.
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  72. GORINI G, Fourati S, Vaccari M, Rahman MA, et al
    Engagement of monocytes, NK cells, and CD4+ Th1 cells by ALVAC-SIV vaccination results in a decreased risk of SIVmac251 vaginal acquisition.
    PLoS Pathog. 2020;16:e1008377.
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  73. WEBB GM, Molden J, Busman-Sahay K, Abdulhaqq S, et al
    The human IL-15 superagonist N-803 promotes migration of virus-specific CD8+ T and NK cells to B cell follicles but does not reverse latency in ART-suppressed, SHIV-infected macaques.
    PLoS Pathog. 2020;16:e1008339.
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  74. RAEHTZ KD, Barrenas F, Xu C, Busman-Sahay K, et al
    African green monkeys avoid SIV disease progression by preventing intestinal dysfunction and maintaining mucosal barrier integrity.
    PLoS Pathog. 2020;16:e1008333.
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  75. DAVID P, Drabczyk-Pluta M, Pastille E, Knuschke T, et al
    Combination immunotherapy with anti-PD-L1 antibody and depletion of regulatory T cells during acute viral infections results in improved virus control but lethal immunopathology.
    PLoS Pathog. 2020;16:e1008340.
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    February 2020
  76. VAN DER SLUIS RM, Zerbato JM, Rhodes JW, Pascoe RD, et al
    Diverse effects of interferon alpha on the establishment and reversal of HIV latency.
    PLoS Pathog. 2020;16:e1008151.
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  77. CHU TH, Crowley AR, Backes I, Chang C, et al
    Hinge length contributes to the phagocytic activity of HIV-specific IgG1 and IgG3 antibodies.
    PLoS Pathog. 2020;16:e1008083.
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  78. COOMER CA, Carlon-Andres I, Iliopoulou M, Dustin ML, et al
    Single-cell glycolytic activity regulates membrane tension and HIV-1 fusion.
    PLoS Pathog. 2020;16:e1008359.
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  79. WONG RW, Balachandran A, Cheung PK, Cheng R, et al
    An activator of G protein-coupled receptor and MEK1/2-ERK1/2 signaling inhibits HIV-1 replication by altering viral RNA processing.
    PLoS Pathog. 2020;16:e1008307.
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  80. JURCZYSZAK D, Zhang W, Terry SN, Kehrer T, et al
    HIV protease cleaves the antiviral m6A reader protein YTHDF3 in the viral particle.
    PLoS Pathog. 2020;16:e1008305.
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  81. PANKAU MD, Reeves DB, Harkins E, Ronen K, et al
    Dynamics of HIV DNA reservoir seeding in a cohort of superinfected Kenyan women.
    PLoS Pathog. 2020;16:e1008286.
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  82. ROLLAND M, Tovanabutra S, Dearlove B, Li Y, et al
    Molecular dating and viral load growth rates suggested that the eclipse phase lasted about a week in HIV-1 infected adults in East Africa and Thailand.
    PLoS Pathog. 2020;16:e1008179.
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  83. SEOANE PI, Taylor-Smith LM, Stirling D, Bell LCK, et al
    Viral infection triggers interferon-induced expulsion of live Cryptococcus neoformans by macrophages.
    PLoS Pathog. 2020;16:e1008240.
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    January 2020
  84. DICK RA, Xu C, Morado DR, Kravchuk V, et al
    Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly.
    PLoS Pathog. 2020;16:e1008277.
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  85. HOANG T, Toler E, DeLong K, Mafunda NA, et al
    The cervicovaginal mucus barrier to HIV-1 is diminished in bacterial vaginosis.
    PLoS Pathog. 2020;16:e1008236.
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  86. GRUFFAZ M, Zhang T, Marshall V, Goncalves P, et al
    Signatures of oral microbiome in HIV-infected individuals with oral Kaposi's sarcoma and cell-associated KSHV DNA.
    PLoS Pathog. 2020;16:e1008114.
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  87. LINDQVIST B, Svensson Akusjarvi S, Sonnerborg A, Dimitriou M, et al
    Chromatin maturation of the HIV-1 provirus in primary resting CD4+ T cells.
    PLoS Pathog. 2020;16:e1008264.
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    December 2019
  88. ALVAREZ-CARBONELL D, Ye F, Ramanath N, Garcia-Mesa Y, et al
    Cross-talk between microglia and neurons regulates HIV latency.
    PLoS Pathog. 2019;15:e1008249.
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  89. RICHARDSON SI, Lambson BE, Crowley AR, Bashirova A, et al
    IgG3 enhances neutralization potency and Fc effector function of an HIV V2-specific broadly neutralizing antibody.
    PLoS Pathog. 2019;15:e1008064.
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  90. WU NR, Nicely NI, Lee EM, Reed RK, et al
    Cooperation between somatic mutation and germline-encoded residues enable antibody recognition of HIV-1 envelope glycans.
    PLoS Pathog. 2019;15:e1008165.
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  91. CURRENTI J, Chopra A, John M, Leary S, et al
    Deep sequence analysis of HIV adaptation following vertical transmission reveals the impact of immune pressure on the evolution of HIV.
    PLoS Pathog. 2019;15:e1008177.
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  92. VENTURA JD, Beloor J, Allen E, Zhang T, et al
    Longitudinal bioluminescent imaging of HIV-1 infection during antiretroviral therapy and treatment interruption in humanized mice.
    PLoS Pathog. 2019;15:e1008161.
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  93. CHEN J, Dai L, Goldstein A, Zhang H, et al
    Identification of new antiviral agents against Kaposi's sarcoma-associated herpesvirus (KSHV) by high-throughput drug screening reveals the role of histamine-related signaling in promoting viral lytic reactivation.
    PLoS Pathog. 2019;15:e1008156.
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  94. FARIA NR, Vidal N, Lourenco J, Raghwani J, et al
    Distinct rates and patterns of spread of the major HIV-1 subtypes in Central and East Africa.
    PLoS Pathog. 2019;15:e1007976.
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  95. BI W, Xu W, Cheng L, Xue J, et al
    IgG Fc-binding motif-conjugated HIV-1 fusion inhibitor exhibits improved potency and in vivo half-life: Potential application in combination with broad neutralizing antibodies.
    PLoS Pathog. 2019;15:e1008082.
    >> Share

  96. SCHIFANELLA L, Barnett SW, Bissa M, Galli V, et al
    ALVAC-HIV B/C candidate HIV vaccine efficacy dependent on neutralization profile of challenge virus and adjuvant dose and type.
    PLoS Pathog. 2019;15:e1008121.
    >> Share

  97. LABRANCHE CC, Henderson R, Hsu A, Behrens S, et al
    Correction: Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies.
    PLoS Pathog. 2019;15:e1008200.
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    October 2019
  98. DAGENAIS-LUSSIER X, Loucif H, Cadorel H, Blumberger J, et al
    USP18 is a significant driver of memory CD4 T-cell reduced viability caused by type I IFN signaling during primary HIV-1 infection.
    PLoS Pathog. 2019;15:e1008060.
    >> Share

  99. PINO M, Paganini S, Deleage C, Padhan K, et al
    Fingolimod retains cytolytic T cells and limits T follicular helper cell infection in lymphoid sites of SIV persistence.
    PLoS Pathog. 2019;15:e1008081.
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  100. WONDERLICH ER, Subramanian K, Cox B, Wiegand A, et al
    Effector memory differentiation increases detection of replication-competent HIV-l in resting CD4+ T cells from virally suppressed individuals.
    PLoS Pathog. 2019;15:e1008074.
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  101. READ DF, Atindaana E, Pyaram K, Yang F, et al
    Stable integrant-specific differences in bimodal HIV-1 expression patterns revealed by high-throughput analysis.
    PLoS Pathog. 2019;15:e1007903.
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  102. PERELYGINA L, Chen MH, Suppiah S, Adebayo A, et al
    Infectious vaccine-derived rubella viruses emerge, persist, and evolve in cutaneous granulomas of children with primary immunodeficiencies.
    PLoS Pathog. 2019;15:e1008080.
    >> Share

    September 2019
  103. GONZALEZ-NIETO L, Castro IM, Bischof GF, Shin YC, et al
    Vaccine protection against rectal acquisition of SIVmac239 in rhesus macaques.
    PLoS Pathog. 2019;15:e1008015.
    >> Share

  104. LABRANCHE CC, Henderson R, Hsu A, Behrens S, et al
    Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancester of CH235 lineage CD4bs broadly neutralizing antibodies.
    PLoS Pathog. 2019;15:e1008026.
    >> Share

  105. SACKS D, Bhiman JN, Wiehe K, Gorman J, et al
    Somatic hypermutation to counter a globally rare viral immunotype drove off-track antibodies in the CAP256-VRC26 HIV-1 V2-directed bNAb lineage.
    PLoS Pathog. 2019;15:e1008005.
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  106. MOUSER EE, Pollakis G, Smits HH, Thomas J, et al
    Schistosoma mansoni soluble egg antigen (SEA) and recombinant Omega-1 modulate induced CD4+ T-lymphocyte responses and HIV-1 infection in vitro.
    PLoS Pathog. 2019;15:e1007924.
    >> Share

  107. SURENAUD M, Montes M, Lindestam Arlehamn CS, Sette A, et al
    Anti-HIV potency of T-cell responses elicited by dendritic cell therapeutic vaccination.
    PLoS Pathog. 2019;15:e1008011.
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    August 2019
  108. CLAIBORNE DT, Scully EP, Palmer CD, Prince JL, et al
    Protective HLA alleles are associated with reduced LPS levels in acute HIV infection with implications for immune activation and pathogenesis.
    PLoS Pathog. 2019;15:e1007981.
    >> Share

  109. GRAU-EXPOSITO J, Luque-Ballesteros L, Navarro J, Curran A, et al
    Latency Reversal Agents Affect Differently the Latent Reservoir Present in Distinct CD4+ T Subpopulations.
    PLoS Pathog. 2019;15:e1007991.
    >> Share

  110. QIN K, Boppana S, Du VY, Carlson JM, et al
    CD8 T cells targeting adapted epitopes in chronic HIV infection promote dendritic cell maturation and CD4 T cell trans-infection.
    PLoS Pathog. 2019;15:e1007970.
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  111. RODRIGUEZ-MORA S, De Wit F, Garcia-Perez J, Bermejo M, et al
    The mutation of Transportin 3 gene that causes limb girdle muscular dystrophy 1F induces protection against HIV-1 infection.
    PLoS Pathog. 2019;15:e1007958.
    >> Share

    July 2019
  112. BANGA R, Rebecchini C, Procopio FA, Noto A, et al
    Lymph node migratory dendritic cells modulate HIV-1 transcription through PD-1 engagement.
    PLoS Pathog. 2019;15:e1007918.
    >> Share

  113. TORRENTS DE LA PENA A, Rantalainen K, Cottrell CA, Allen JD, et al
    Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics.
    PLoS Pathog. 2019;15:e1007920.
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  114. HYUN J, McMahon RS, Lang AL, Edwards JS, et al
    HIV and HCV augments inflammatory responses through increased TREM-1 expression and signaling in Kupffer and Myeloid cells.
    PLoS Pathog. 2019;15:e1007883.
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  115. SHARMA A, McLaughlin RN Jr, Basom RS, Kikawa C, et al
    Macaque interferon-induced transmembrane proteins limit replication of SHIV strains in an Envelope-dependent manner.
    PLoS Pathog. 2019;15:e1007925.
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  116. FERRIS AL, Wells DW, Guo S, Del Prete GQ, et al
    Clonal expansion of SIV-infected cells in macaques on antiretroviral therapy is similar to that of HIV-infected cells in humans.
    PLoS Pathog. 2019;15:e1007869.
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  117. MUKHAMEDOVA N, Hoang A, Dragoljevic D, Dubrovsky L, et al
    Exosomes containing HIV protein Nef reorganize lipid rafts potentiating inflammatory response in bystander cells.
    PLoS Pathog. 2019;15:e1007907.
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  118. PASSALACQUA KD, Purdy JG, Wobus CE
    The inert meets the living: The expanding view of metabolic alterations during viral pathogenesis.
    PLoS Pathog. 2019;15:e1007830.
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    June 2019
  119. HANI L, Chaillon A, Nere ML, Ruffin N, et al
    Proliferative memory SAMHD1low CD4+ T cells harbour high levels of HIV-1 with compartmentalized viral populations.
    PLoS Pathog. 2019;15:e1007868.
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  120. ZHOU P, Wang H, Fang M, Li Y, et al
    Broadly resistant HIV-1 against CD4-binding site neutralizing antibodies.
    PLoS Pathog. 2019;15:e1007819.
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  121. FOURCADE L, Sabourin-Poirier C, Perraud V, Faucher MC, et al
    Natural Immunity to HIV is associated with Low BLyS/BAFF levels and low frequencies of innate marginal zone like CD1c+ B-cells in the genital tract.
    PLoS Pathog. 2019;15:e1007840.
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    May 2019
  122. GAGNE M, Michaels D, Schiralli Lester GM, Gummuluru S, et al
    Strength of T cell signaling regulates HIV-1 replication and establishment of latency.
    PLoS Pathog. 2019;15:e1007802.
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  123. SAMRI A, Charpentier C, Diallo M, Bertine M, et al
    Limited HIV-2 reservoirs in central-memory CD4 T-cells associated to CXCR6 co-receptor expression in attenuated HIV-2 infection.
    PLoS Pathog. 2019;15:e1007758.
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  124. CALENDA G, Frank I, Arrode-Bruses G, Pegu A, et al
    Delayed vaginal SHIV infection in VRC01 and anti-alpha4beta7 treated rhesus macaques.
    PLoS Pathog. 2019;15:e1007776.
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  125. ROUX A, Leroy H, De Muylder B, Bracq L, et al
    FOXO1 transcription factor plays a key role in T cell-HIV-1 interaction.
    PLoS Pathog. 2019;15:e1007669.
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    April 2019
  126. WANG L, Howell MEA, Sparks-Wallace A, Hawkins C, et al
    p62-mediated Selective autophagy endows virus-transformed cells with insusceptibility to DNA damage under oxidative stress.
    PLoS Pathog. 2019;15:e1007541.
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  127. LI SX, Sen S, Schneider JM, Xiong KN, et al
    Gut microbiota from high-risk men who have sex with men drive immune activation in gnotobiotic mice and in vitro HIV infection.
    PLoS Pathog. 2019;15:e1007611.
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  128. O'BRIEN SP, Swanstrom AE, Pegu A, Ko SY, et al
    Rational design and in vivo selection of SHIVs encoding transmitted/founder subtype C HIV-1 envelopes.
    PLoS Pathog. 2019;15:e1007632.
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  129. HENSLEY-MCBAIN T, Wu MC, Manuzak JA, Cheu RK, et al
    Increased mucosal neutrophil survival is associated with altered microbiota in HIV infection.
    PLoS Pathog. 2019;15:e1007672.
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    March 2019
  130. LI S, Folkvord JM, Kovacs KJ, Wagstaff RK, et al
    Low levels of SIV-specific CD8+ T cells in germinal centers characterizes acute SIV infection.
    PLoS Pathog. 2019;15:e1007311.
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  131. LABRANCHE CC, McGuire AT, Gray MD, Behrens S, et al
    Correction: HIV-1 envelope glycan modifications that permit neutralization by germline-reverted VRC01-class broadly neutralizing antibodies.
    PLoS Pathog. 2019;15:e1007646.
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    February 2019
  132. PARDONS M, Baxter AE, Massanella M, Pagliuzza A, et al
    Single-cell characterization and quantification of translation-competent viral reservoirs in treated and untreated HIV infection.
    PLoS Pathog. 2019;15:e1007619.
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  133. WILLIAMS KL, Stumpf M, Naiman NE, Ding S, et al
    Identification of HIV gp41-specific antibodies that mediate killing of infected cells.
    PLoS Pathog. 2019;15:e1007572.
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  134. HAGEN B, Kraase M, Indikova I, Indik S, et al
    A high rate of polymerization during synthesis of mouse mammary tumor virus DNA alleviates hypermutation by APOBEC3 proteins.
    PLoS Pathog. 2019;15:e1007533.
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  135. CHONG H, Xue J, Zhu Y, Cong Z, et al
    Monotherapy with a low-dose lipopeptide HIV fusion inhibitor maintains long-term viral suppression in rhesus macaques.
    PLoS Pathog. 2019;15:e1007552.
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  136. MACKELPRANG RD, Bamshad MJ, Chong JX, Hou X, et al
    Correction: Whole genome sequencing of extreme phenotypes identifies variants in CD101 and UBE2V1 associated with increased risk of sexually acquired HIV-1.
    PLoS Pathog. 2019;15:e1007588.
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  137. D'SOUZA MP, Adams E, Altman JD, Birnbaum ME, et al
    Casting a wider net: Immunosurveillance by nonclassical MHC molecules.
    PLoS Pathog. 2019;15:e1007567.
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    January 2019
  138. LI Z, Wu J, Chavez L, Hoh R, et al
    Reiterative Enrichment and Authentication of CRISPRi Targets (REACT) identifies the proteasome as a key contributor to HIV-1 latency.
    PLoS Pathog. 2019;15:e1007498.
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  139. GRAYDON CG, Balasko AL, Fowke KR
    Roles, function and relevance of LAG3 in HIV infection.
    PLoS Pathog. 2019;15:e1007429.
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    December 2018
  140. ROSE TM, Bruce AG, Barcy S, Fitzgibbon M, et al
    Quantitative RNAseq analysis of Ugandan KS tumors reveals KSHV gene expression dominated by transcription from the LTd downstream latency promoter.
    PLoS Pathog. 2018;14:e1007441.
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  141. WELLES HC, Jennewein MF, Mason RD, Narpala S, et al
    Vectored delivery of anti-SIV envelope targeting mAb via AAV8 protects rhesus macaques from repeated limiting dose intrarectal swarm SIVsmE660 challenge.
    PLoS Pathog. 2018;14:e1007395.
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  142. COLIN P, Zhou Z, Staropoli I, Garcia-Perez J, et al
    CCR5 structural plasticity shapes HIV-1 phenotypic properties.
    PLoS Pathog. 2018;14:e1007432.
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    November 2018
  143. SIDDIQUI R, Suzu S, Ueno M, Nasser H, et al
    Apolipoprotein E is an HIV-1-inducible inhibitor of viral production and infectivity in macrophages.
    PLoS Pathog. 2018;14:e1007372.
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  144. MERINDOL N, El-Far M, Sylla M, Masroori N, et al
    HIV-1 capsids from B27/B57+ elite controllers escape Mx2 but are targeted by TRIM5alpha, leading to the induction of an antiviral state.
    PLoS Pathog. 2018;14:e1007398.
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  145. LEOZ M, Kukanja P, Luo Z, Huang F, et al
    HEXIM1-Tat chimera inhibits HIV-1 replication.
    PLoS Pathog. 2018;14:e1007402.
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  146. LABRANCHE CC, McGuire AT, Gray MD, Behrens S, et al
    HIV-1 Envelope Glycan Modifications that Permit Neutralization by Germline-Reverted VRC01-Class Broadly Neutralizing Antibodies.
    PLoS Pathog. 2018;14:e1007431.
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  147. GOULDER P, Deeks SG
    HIV control: Is getting there the same as staying there?
    PLoS Pathog. 2018;14:e1007222.
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  148. TELWATTE S, Lee S, Somsouk M, Hatano H, et al
    Gut and blood differ in constitutive blocks to HIV transcription, suggesting tissue-specific differences in the mechanisms that govern HIV latency.
    PLoS Pathog. 2018;14:e1007357.
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  149. DICKS MDJ, Betancor G, Jimenez-Guardeno JM, Pessel-Vivares L, et al
    Multiple components of the nuclear pore complex interact with the amino-terminus of MX2 to facilitate HIV-1 restriction.
    PLoS Pathog. 2018;14:e1007408.
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    October 2018
  150. CAO Y, Cartwright EK, Silvestri G, Perelson AS, et al
    CD8+ lymphocyte control of SIV infection during antiretroviral therapy.
    PLoS Pathog. 2018;14:e1007350.
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  151. RAWLE DJ, Harrich D
    Toward the "unravelling" of HIV: Host cell factors involved in HIV-1 core uncoating.
    PLoS Pathog. 2018;14:e1007270.
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    "APP"reciating the complexity of HIV-induced neurodegenerative diseases.
    PLoS Pathog. 2018;14:e1007309.
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    September 2018
  153. AHMED A, Adiga V, Nayak S, Uday Kumar JAJ, et al
    Circulating HLA-DR+CD4+ effector memory T cells resistant to CCR5 and PD-L1 mediated suppression compromise regulatory T cell function in tuberculosis.
    PLoS Pathog. 2018;14:e1007289.
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  154. BACHTEL ND, Umviligihozo G, Pickering S, Mota T, et al
    HLA-C downregulation by HIV-1 adapts to host HLA genotype.
    PLoS Pathog. 2018;14:e1007257.
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    August 2018
  155. CHAUDHARY O, Narayan V, Lelis F, Linz B, et al
    Inhibition of p38MAPK in combination with ART reduces SIV-induced immune activation and provides additional protection from immune system deterioration.
    PLoS Pathog. 2018;14:e1007268.
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  156. LERTJUTHAPORN S, Cicala C, Van Ryk D, Liu M, et al
    Select gp120 V2 domain specific antibodies derived from HIV and SIV infection and vaccination inhibit gp120 binding to alpha4beta7.
    PLoS Pathog. 2018;14:e1007278.
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  157. NGANOU-MAKAMDOP K, Billingsley JM, Yaffe Z, O'Connor G, et al
    Type I IFN signaling blockade by a PASylated antagonist during chronic SIV infection suppresses specific inflammatory pathways but does not alter T cell activation or virus replication.
    PLoS Pathog. 2018;14:e1007246.
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  158. OTSUKA Y, Schmitt K, Quinlan BD, Gardner MR, et al
    Diverse pathways of escape from all well-characterized VRC01-class broadly neutralizing HIV-1 antibodies.
    PLoS Pathog. 2018;14:e1007238.
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  159. KMIEC D, Akbil B, Ananth S, Hotter D, et al
    SIVcol Nef counteracts SERINC5 by promoting its proteasomal degradation but does not efficiently enhance HIV-1 replication in human CD4+ T cells and lymphoid tissue.
    PLoS Pathog. 2018;14:e1007269.
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    July 2018
  160. RAGHWANI J, Redd AD, Longosz AF, Wu CH, et al
    Evolution of HIV-1 within untreated individuals and at the population scale in Uganda.
    PLoS Pathog. 2018;14:e1007167.
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  161. DZHIVHUHO GA, Rehrl SA, Ndlovu H, Horsnell WGC, et al
    Chronic schistosomiasis suppresses HIV-specific responses to DNA-MVA and MVA-gp140 Env vaccine regimens despite antihelminthic treatment and increases helminth-associated pathology in a mouse model.
    PLoS Pathog. 2018;14:e1007182.
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  162. DINGENS AS, Acharya P, Haddox HK, Rawi R, et al
    Complete functional mapping of infection- and vaccine-elicited antibodies against the fusion peptide of HIV.
    PLoS Pathog. 2018;14:e1007159.
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  163. MARSHALL VA, Labo N, Hao XP, Holdridge B, et al
    Gammaherpesvirus infection and malignant disease in rhesus macaques experimentally infected with SIV or SHIV.
    PLoS Pathog. 2018;14:e1007130.
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    June 2018
  164. YACOOB C, Lange MD, Cohen K, Lathia K, et al
    B cell clonal lineage alterations upon recombinant HIV-1 envelope immunization of rhesus macaques.
    PLoS Pathog. 2018;14:e1007120.
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  165. SHIN YC, Bischof GF, Lauer WA, Gonzalez-Nieto L, et al
    A recombinant herpesviral vector containing a near-full-length SIVmac239 genome produces SIV particles and elicits immune responses to all nine SIV gene products.
    PLoS Pathog. 2018;14:e1007143.
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  166. WANAGURU M, Barry DJ, Benton DJ, O'Reilly NJ, et al
    Murine leukemia virus p12 tethers the capsid-containing pre-integration complex to chromatin by binding directly to host nucleosomes in mitosis.
    PLoS Pathog. 2018;14:e1007117.
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  167. ELLETT F, Pazhakh V, Pase L, Benard EL, et al
    Macrophages protect Talaromyces marneffei conidia from myeloperoxidase-dependent neutrophil fungicidal activity during infection establishment in vivo.
    PLoS Pathog. 2018;14:e1007063.
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  168. GU CJ, Borjabad A, Hadas E, Kelschenbach J, et al
    EcoHIV infection of mice establishes latent viral reservoirs in T cells and active viral reservoirs in macrophages that are sufficient for induction of neurocognitive impairment.
    PLoS Pathog. 2018;14:e1007061.
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    May 2018
  169. RAM DR, Manickam C, Hueber B, Itell HL, et al
    Tracking KLRC2 (NKG2C)+ memory-like NK cells in SIV+ and rhCMV+ rhesus macaques.
    PLoS Pathog. 2018;14:e1007104.
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  170. XU M, Moresco JJ, Chang M, Mukim A, et al
    SHMT2 and the BRCC36/BRISC deubiquitinase regulate HIV-1 Tat K63-ubiquitylation and destruction by autophagy.
    PLoS Pathog. 2018;14:e1007071.
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  171. ROTEM E, Faingold O, Charni M, Klug YA, et al
    The HTLV-1 gp21 fusion peptide inhibits antigen specific T-cell activation in-vitro and in mice.
    PLoS Pathog. 2018;14:e1007044.
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  172. CROOKS ET, Grimley SL, Cully M, Osawa K, et al
    Glycoengineering HIV-1 Env creates 'supercharged' and 'hybrid' glycans to increase neutralizing antibody potency, breadth and saturation.
    PLoS Pathog. 2018;14:e1007024.
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  173. SCHIFFNER T, Pallesen J, Russell RA, Dodd J, et al
    Structural and immunologic correlates of chemically stabilized HIV-1 envelope glycoproteins.
    PLoS Pathog. 2018;14:e1006986.
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    April 2018
  174. ENOSE-AKAHATA Y, Azodi S, Smith BR, Billioux BJ, et al
    Immunophenotypic characterization of CSF B cells in virus-associated neuroinflammatory diseases.
    PLoS Pathog. 2018;14:e1007042.
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  175. LI Z, Mbonye U, Feng Z, Wang X, et al
    The KAT5-Acetyl-Histone4-Brd4 axis silences HIV-1 transcription and promotes viral latency.
    PLoS Pathog. 2018;14:e1007012.
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  176. IKEDA T, Symeonides M, Albin JS, Li M, et al
    HIV-1 adaptation studies reveal a novel Env-mediated homeostasis mechanism for evading lethal hypermutation by APOBEC3G.
    PLoS Pathog. 2018;14:e1007010.
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  177. BARAJAS BC, Tanaka M, Robinson BA, Phuong DJ, et al
    Identifying the assembly intermediate in which Gag first associates with unspliced HIV-1 RNA suggests a novel model for HIV-1 RNA packaging.
    PLoS Pathog. 2018;14:e1006977.
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  178. WETZEL KS, Yi Y, Yadav A, Bauer AM, et al
    Loss of CXCR6 coreceptor usage characterizes pathogenic lentiviruses.
    PLoS Pathog. 2018;14:e1007003.
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  179. BUGGERT M, Nguyen S, McLane LM, Steblyanko M, et al
    Limited immune surveillance in lymphoid tissue by cytolytic CD4+ T cells during health and HIV disease.
    PLoS Pathog. 2018;14:e1006973.
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  180. RICHARDSON SI, Chung AW, Natarajan H, Mabvakure B, et al
    HIV-specific Fc effector function early in infection predicts the development of broadly neutralizing antibodies.
    PLoS Pathog. 2018;14:e1006987.
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  181. PETERSON CW, Wang J, Deleage C, Reddy S, et al
    Differential impact of transplantation on peripheral and tissue-associated viral reservoirs: Implications for HIV gene therapy.
    PLoS Pathog. 2018;14:e1006956.
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  182. KUMAR A, Smith CEP, Giorgi EE, Eudailey J, et al
    Infant transmitted/founder HIV-1 viruses from peripartum transmission are neutralization resistant to paired maternal plasma.
    PLoS Pathog. 2018;14:e1006944.
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    March 2018
  183. CONTRERAS X, Salifou K, Sanchez G, Helsmoortel M, et al
    Nuclear RNA surveillance complexes silence HIV-1 transcription.
    PLoS Pathog. 2018;14:e1006950.
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  184. CHITRE AS, Kattah MG, Rosli YY, Pao M, et al
    A20 upregulation during treated HIV disease is associated with intestinal epithelial cell recovery and function.
    PLoS Pathog. 2018;14:e1006806.
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  185. WAGH K, Seaman MS, Zingg M, Fitzsimons T, et al
    Potential of conventional & bispecific broadly neutralizing antibodies for prevention of HIV-1 subtype A, C & D infections.
    PLoS Pathog. 2018;14:e1006860.
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  186. MEYERSON NR, Warren CJ, Vieira DASA, Diaz-Griferro F, et al
    Species-specific vulnerability of RanBP2 shaped the evolution of SIV as it transmitted in African apes.
    PLoS Pathog. 2018;14:e1006906.
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  187. ZHEN A, Peterson CW, Carrillo MA, Reddy SS, et al
    Correction: Long-term persistence and function of hematopoietic stem cell-derived chimeric antigen receptor T cells in a nonhuman primate model of HIV/AIDS.
    PLoS Pathog. 2018;14:e1006891.
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    February 2018
  188. AUCLAIR S, Liu F, Niu Q, Hou W, et al
    Distinct susceptibility of HIV vaccine vector-induced CD4 T cells to HIV infection.
    PLoS Pathog. 2018;14:e1006888.
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  189. KLASSE PJ, Ketas TJ, Cottrell CA, Ozorowski G, et al
    Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques.
    PLoS Pathog. 2018;14:e1006913.
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  190. FISHER BS, Green RR, Brown RR, Wood MP, et al
    Liver macrophage-associated inflammation correlates with SIV burden and is substantially reduced following cART.
    PLoS Pathog. 2018;14:e1006871.
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  191. KUHNERT D, Kouyos R, Shirreff G, Pecerska J, et al
    Quantifying the fitness cost of HIV-1 drug resistance mutations through phylodynamics.
    PLoS Pathog. 2018;14:e1006895.
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  192. HASENKRUG KJ, Chougnet CA, Dittmer U
    Regulatory T cells in retroviral infections.
    PLoS Pathog. 2018;14:e1006776.
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  193. WATSON DC, Moysi E, Valentin A, Bergamaschi C, et al
    Treatment with native heterodimeric IL-15 increases cytotoxic lymphocytes and reduces SHIV RNA in lymph nodes.
    PLoS Pathog. 2018;14:e1006902.
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  194. HOGAN LE, Vasquez J, Hobbs KS, Hanhauser E, et al
    Increased HIV-1 transcriptional activity and infectious burden in peripheral blood and gut-associated CD4+ T cells expressing CD30.
    PLoS Pathog. 2018;14:e1006856.
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    January 2018
  195. TAKATA M, Soll SJ, Emery A, Blanco-Melo D, et al
    Global synonymous mutagenesis identifies cis-acting RNA elements that regulate HIV-1 splicing and replication.
    PLoS Pathog. 2018;14:e1006824.
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  196. UPADHYAY C, Feyznezhad R, Yang W, Zhang H, et al
    Alterations of HIV-1 envelope phenotype and antibody-mediated neutralization by signal peptide mutations.
    PLoS Pathog. 2018;14:e1006812.
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  197. REH L, Magnus C, Kadelka C, Kuhnert D, et al
    Phenotypic deficits in the HIV-1 envelope are associated with the maturation of a V2-directed broadly neutralizing antibody lineage.
    PLoS Pathog. 2018;14:e1006825.
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  198. GALILEE M, Alian A
    The structure of FIV reverse transcriptase and its implications for non-nucleoside inhibitor resistance.
    PLoS Pathog. 2018;14:e1006849.
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  199. TSO FY, Kossenkov AV, Lidenge SJ, Ngalamika O, et al
    RNA-Seq of Kaposi's sarcoma reveals alterations in glucose and lipid metabolism.
    PLoS Pathog. 2018;14:e1006844.
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  200. ZHAO J, Cheng L, Wang H, Yu H, et al
    Infection and depletion of CD4+ group-1 innate lymphoid cells by HIV-1 via type-I interferon pathway.
    PLoS Pathog. 2018;14:e1006819.
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  201. BINNING JM, Smith AM, Hultquist JF, Craik CS, et al
    Fab-based inhibitors reveal ubiquitin independent functions for HIV Vif neutralization of APOBEC3 restriction factors.
    PLoS Pathog. 2018;14:e1006830.
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  202. KLEIN K, Nickel G, Nankya I, Kyeyune F, et al
    Higher sequence diversity in the vaginal tract than in blood at early HIV-1 infection.
    PLoS Pathog. 2018;14:e1006754.
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  203. CLARRIDGE KE, Blazkova J, Einkauf K, Petrone M, et al
    Effect of analytical treatment interruption and reinitiation of antiretroviral therapy on HIV reservoirs and immunologic parameters in infected individuals.
    PLoS Pathog. 2018;14:e1006792.
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    December 2017
  204. GACH JS, Bouzin M, Wong MP, Chromikova V, et al
    Human Immunodeficiency Virus type-1 (HIV-1) evades antibody-dependent phagocytosis.
    PLoS Pathog. 2017;13:e1006793.
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  205. DAVIS-GARDNER ME, Gardner MR, Alfant B, Farzan M, et al
    eCD4-Ig promotes ADCC activity of sera from HIV-1-infected patients.
    PLoS Pathog. 2017;13:e1006786.
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  206. ZHEN A, Peterson CW, Carrillo MA, Reddy SS, et al
    Long-term persistence and function of hematopoietic stem cell-derived chimeric antigen receptor T cells in a nonhuman primate model of HIV/AIDS.
    PLoS Pathog. 2017;13:e1006753.
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  207. GAVEGNANO C, Brehm JH, Dupuy FP, Talla A, et al
    Novel mechanisms to inhibit HIV reservoir seeding using Jak inhibitors.
    PLoS Pathog. 2017;13:e1006740.
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  208. ZHANG Z, Gu Q, de Manuel Montero M, Bravo IG, et al
    Stably expressed APOBEC3H forms a barrier for cross-species transmission of simian immunodeficiency virus of chimpanzee to humans.
    PLoS Pathog. 2017;13:e1006746.
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    November 2017
  209. MACKELPRANG RD, Bamshad MJ, Chong JX, Hou X, et al
    Whole genome sequencing of extreme phenotypes identifies variants in CD101 and UBE2V1 associated with increased risk of sexually acquired HIV-1.
    PLoS Pathog. 2017;13:e1006703.
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  210. MCBRIDE JA, Striker R
    Imbalance in the game of T cells: What can the CD4/CD8 T-cell ratio tell us about HIV and health?
    PLoS Pathog. 2017;13:e1006624.
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    October 2017
  211. BAILEY AL, Buechler CR, Matson DR, Peterson EJ, et al
    Pegivirus avoids immune recognition but does not attenuate acute-phase disease in a macaque model of HIV infection.
    PLoS Pathog. 2017;13:e1006692.
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  212. ROGANOWICZ MD, Komurlu S, Mukherjee S, Plewka J, et al
    TRIM5alpha SPRY/coiled-coil interactions optimize avid retroviral capsid recognition.
    PLoS Pathog. 2017;13:e1006686.
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  213. PORTILLO JC, Muniz-Feliciano L, Lopez Corcino Y, Lee SJ, et al
    Toxoplasma gondii induces FAK-Src-STAT3 signaling during infection of host cells that prevents parasite targeting by autophagy.
    PLoS Pathog. 2017;13:e1006671.
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  214. LEIBMAN RS, Richardson MW, Ellebrecht CT, Maldini CR, et al
    Supraphysiologic control over HIV-1 replication mediated by CD8 T cells expressing a re-engineered CD4-based chimeric antigen receptor.
    PLoS Pathog. 2017;13:e1006613.
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  215. RATO S, Rausell A, Munoz M, Telenti A, et al
    Single-cell analysis identifies cellular markers of the HIV permissive cell.
    PLoS Pathog. 2017;13:e1006678.
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    September 2017
  216. OBENG-ADJEI N, Portugal S, Holla P, Li S, et al
    Malaria-induced interferon-gamma drives the expansion of Tbethi atypical memory B cells.
    PLoS Pathog. 2017;13:e1006576.
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  217. DEL PRETE GQ, Keele BF, Fode J, Thumar K, et al
    A single gp120 residue can affect HIV-1 tropism in macaques.
    PLoS Pathog. 2017;13:e1006572.
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  218. ABERE B, Mamo TM, Hartmann S, Samarina N, et al
    The Kaposi's sarcoma-associated herpesvirus (KSHV) non-structural membrane protein K15 is required for viral lytic replication and may represent a therapeutic target.
    PLoS Pathog. 2017;13:e1006639.
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  219. ALLARD A, Althouse BM, Hebert-Dufresne L, Scarpino SV, et al
    The risk of sustained sexual transmission of Zika is underestimated.
    PLoS Pathog. 2017;13:e1006633.
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  220. THOMAS AS, Jones KL, Gandhi RT, McMahon DK, et al
    mT-cell responses targeting HIV Nef uniquely correlate with infected cell frequencies after long-term antiretroviral therapy.
    PLoS Pathog. 2017;13:e1006629.
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  221. SEKI S, Nomura T, Nishizawa M, Yamamoto H, et al
    In vivo virulence of MHC-adapted AIDS virus serially-passaged through MHC-mismatched hosts.
    PLoS Pathog. 2017;13:e1006638.
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  222. SHRESTHA P, Davis DA, Veeranna RP, Carey RF, et al
    Hypoxia-inducible factor-1 alpha as a therapeutic target for primary effusion lymphoma.
    PLoS Pathog. 2017;13:e1006628.
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  223. DUBROVSKAYA V, Guenaga J, de Val N, Wilson R, et al
    Targeted N-glycan deletion at the receptor-binding site retains HIV Env NFL trimer integrity and accelerates the elicited antibody response.
    PLoS Pathog. 2017;13:e1006614.
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  224. KIJAK GH, Sanders-Buell E, Chenine AL, Eller MA, et al
    Correction: Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection.
    PLoS Pathog. 2017;13:e1006620.
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  225. Correction: CD4 is expressed on a heterogeneous subset of hematopoietic progenitors, which persistently harbor CXCR4 and CCR5-tropic HIV proviral genomes in vivo.
    PLoS Pathog. 2017;13:e1006617.
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  226. MARSDEN MD, Loy BA, Wu X, Ramirez CM, et al
    In vivo activation of latent HIV with a synthetic bryostatin analog effects both latent cell "kick" and "kill" in strategy for virus eradication.
    PLoS Pathog. 2017;13:e1006575.
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  227. TARTOUR K, Nguyen XN, Appourchaux R, Assil S, et al
    Interference with the production of infectious viral particles and bimodal inhibition of replication are broadly conserved antiviral properties of IFITMs.
    PLoS Pathog. 2017;13:e1006610.
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  228. RADEMEYER C, Korber B, Seaman MS, Giorgi EE, et al
    Correction: Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization.
    PLoS Pathog. 2017;13:e1006641.
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