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Articles published in
Proc Natl Acad Sci U S A
    November 2026
  1. PHELPS CC, Smith S, Gridley J, Kohout JA, et al
    Hepatitis C viral variants bear signatures of de novo CD8+ T cell and antibody pressure after spontaneous postpartum viral suppression.
    Proc Natl Acad Sci U S A. 2026;123:e2610110123.
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    July 2026
  2. YADAV KK, Bhandari M, Mahsoub HM, Park YB, et al
    Fatty acid regulation and phosphatidylethanolamine biosynthesis are important for hepatitis E virus replication.
    Proc Natl Acad Sci U S A. 2026;123:e2614150123.
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    June 2026
  3. NIKLASCH M, Wingert I, Fogeron ML, Nassal M, et al
    Hepatitis B virus genome packaging and replication are coordinated by a polymerase-responsive RNA switch in the RNA element epsilon.
    Proc Natl Acad Sci U S A. 2026;123:e2537974123.
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    May 2026
  4. LIU K, Zhao Y, Wang Y, Tsikari T, et al
    Deciphering and targeting the pathogenic circuit of nonlytic hepatitis E virus infection using macrophage-augmented organoids.
    Proc Natl Acad Sci U S A. 2026;123:e2603870123.
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    April 2026
  5. HONG X, Brousseau G, Chen HA, Freije CA, et al
    Hepatitis B virus covalently closed circular DNA formation in murine hepatic cells uncovers a late entry block.
    Proc Natl Acad Sci U S A. 2026;123:e2603476123.
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  6. SHIOTA T, Zhao Y, Shiota I, Duyvesteyn HME, et al
    The low-density lipoprotein receptor LDLR mediates cellular entry of nonenveloped hepatitis A virus.
    Proc Natl Acad Sci U S A. 2026;123:e2534261123.
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    March 2026
  7. JU X, Dong L, Liu T, Zhang F, et al
    EIF4H and YBX1 are essential host factors for hepatitis E virus replication and pathogenesis.
    Proc Natl Acad Sci U S A. 2026;123:e2529289123.
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    January 2026
  8. HE Y, Zhong L, DeSilva AR, Kwok KS, et al
    Antibody responses to a highly conserved peptide in HCV E2 protein correlate with chronicity or spontaneous clearance of HCV infection.
    Proc Natl Acad Sci U S A. 2026;123:e2522340122.
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    December 2025
  9. IWASAKI W, Kashiwagi K, Sakamoto A, Nishimoto M, et al
    Structural insights into the role of eIF3 in translation mediated by the HCV IRES.
    Proc Natl Acad Sci U S A. 2025;122:e2505538122.
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  10. WANG Y, Tian H, Shi N, Wu C, et al
    The prion-like characteristic of ORF3 contributes to virion release and pathogenesis of hepatitis E virus.
    Proc Natl Acad Sci U S A. 2025;122:e2511801122.
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    October 2025
  11. TANAKA T, Akaike Y, Kasai H, Yamashita A, et al
    Identification of claudin-3 as an entry factor for rat hepacivirus.
    Proc Natl Acad Sci U S A. 2025;122:e2508736122.
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    June 2025
  12. TANAKA H, Diogo Dias J, Jay B, Kita S, et al
    Structural basis of the hepatitis B virus X protein in complex with DDB1.
    Proc Natl Acad Sci U S A. 2025;122:e2421325122.
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    May 2025
  13. YANG Y, Delcourte L, van Belleghem C, Fonte S, et al
    Structure and nucleic acid interactions of the S(Delta60) domain of the hepatitis delta virus small antigen.
    Proc Natl Acad Sci U S A. 2025;122:e2411890122.
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  14. TIAN D, Li W, Heffron CL, Mahsoub HM, et al
    Antiviral resistance and barrier integrity at the maternal-fetal interface restrict hepatitis E virus from crossing the placental barrier.
    Proc Natl Acad Sci U S A. 2025;122:e2501128122.
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    April 2025
  15. RADIC L, Offersgaard A, Kadava T, Zon I, et al
    Bispecific antibodies against the hepatitis C virus E1E2 envelope glycoprotein.
    Proc Natl Acad Sci U S A. 2025;122:e2420402122.
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    March 2025
  16. ZHANG F, Xu LD, Wu S, Wu Q, et al
    Proteasomal processing of the viral replicase ORF1 facilitates HEV-induced liver fibrosis.
    Proc Natl Acad Sci U S A. 2025;122:e2419946122.
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  17. SARWAR S, Randall G
    HCV NS3/4A protease relocalizes CCTalpha to viral replication sites, enhancing phosphatidylcholine synthesis and viral replication.
    Proc Natl Acad Sci U S A. 2025;122:e2419632122.
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    February 2025
  18. RUST LN, Wettengel JM, Biswas S, Ryu J, et al
    Liver-specific transgenic expression of human NTCP in rhesus macaques confers HBV susceptibility on primary hepatocytes.
    Proc Natl Acad Sci U S A. 2025;122:e2413771122.
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    January 2025
  19. LIU X, Liu T, Shao Z, Xiong X, et al
    Palmitoylation-dependent association with Annexin II directs hepatitis E virus ORF3 sorting into vesicles and quasi-enveloped virions.
    Proc Natl Acad Sci U S A. 2025;122:e2418751122.
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    December 2024
  20. JO WK, Anzolini Cassiano MH, de Oliveira-Filho EF, Brunink S, et al
    Ancient evolutionary origins of hepatitis E virus in rodents.
    Proc Natl Acad Sci U S A. 2024;121:e2413665121.
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  21. ZHENG M, Zhou L, Huang Y, Zhang X, et al
    Structural basis for the synergetic neutralization of hepatitis E virus by antibody-antibody interaction.
    Proc Natl Acad Sci U S A. 2024;121:e2408585121.
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    November 2024
  22. JAGST M, Gomer A, Augustyniak S, Klohn M, et al
    Modeling extrahepatic hepatitis E virus infection in induced human primary neurons.
    Proc Natl Acad Sci U S A. 2024;121:e2411434121.
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  23. GUO H, Xu J, Situ J, Li C, et al
    Cell binding tropism of rat hepatitis E virus is a pivotal determinant of its zoonotic transmission to humans.
    Proc Natl Acad Sci U S A. 2024;121:e2416255121.
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    June 2024
  24. HAMMEL A, Cucos LM, Caras I, Ionescu I, et al
    The red alga Porphyridium as a host for molecular farming: Efficient production of immunologically active hepatitis C virus glycoprotein.
    Proc Natl Acad Sci U S A. 2024;121:e2400145121.
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  25. SU PA, Chang CH, Yen SB, Wu HY, et al
    Epitranscriptomic cytidine methylation of the hepatitis B viral RNA is essential for viral reverse transcription and particle production.
    Proc Natl Acad Sci U S A. 2024;121:e2400378121.
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    April 2024
  26. PAPINI C, Ullah I, Ranjan AP, Zhang S, et al
    Proof-of-concept studies with a computationally designed M(pro) inhibitor as a synergistic combination regimen alternative to Paxlovid.
    Proc Natl Acad Sci U S A. 2024;121:e2320713121.
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    February 2024
  27. KOONIN EV
    Circular RNAs from linear viral RNA genomes: A distinct dimension in the virus world.
    Proc Natl Acad Sci U S A. 2024;121:e2401335121.
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  28. CAO QM, Boonchuen P, Chen TC, Lei S, et al
    Virus-derived circular RNAs populate hepatitis C virus-infected cells.
    Proc Natl Acad Sci U S A. 2024;121:e2313002121.
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    December 2023
  29. OECHSLIN N, Da Silva N, Ankavay M, Moradpour D, et al
    A genome-wide CRISPR/Cas9 screen identifies a role for Rab5A and early endosomes in hepatitis E virus replication.
    Proc Natl Acad Sci U S A. 2023;120:e2307423120.
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  30. XIA Y, Cheng X, Nilsson T, Zhang M, et al
    Nucleolin binds to and regulates transcription of hepatitis B virus covalently closed circular DNA minichromosome.
    Proc Natl Acad Sci U S A. 2023;120:e2306390120.
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    November 2023
  31. ZHOU J, Sukhova K, Peacock TP, McKay PF, et al
    Omicron breakthrough infections in vaccinated or previously infected hamsters.
    Proc Natl Acad Sci U S A. 2023;120:e2308655120.
    >> Share


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