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Articles published in
Gut
    August 2025
  1. FAN T, Wang J, Zhu C, Wu C, et al
    Prevalence of serum HBsAg <100 IU/mL in inactive chronic hepatitis B.
    Gut. 2025 Aug 24:gutjnl-2025-336520. doi: 10.1136/gutjnl-2025-336520.
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  2. SU CW, Liang YJ, Wu JC
    Unravelling the heterogeneous HCC risk in indeterminate chronic hepatitis B.
    Gut. 2025 Aug 18:gutjnl-2025-335915. doi: 10.1136/gutjnl-2025-335915.
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  3. HUI RW, Wu TK, Ho KC, Leung RH, et al
    Large-scale profile study on hepatitis B surface antigen levels in chronic hepatitis B: implications for drug development targeting functional cure.
    Gut. 2025 Aug 5:gutjnl-2025-335219. doi: 10.1136/gutjnl-2025-335219.
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    July 2025
  4. SETO WK, Lok A
    Partial cure of chronic hepatitis B: potential implications for HCC surveillance?
    Gut. 2025 Jul 29:gutjnl-2025-336032. doi: 10.1136/gutjnl-2025-336032.
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  5. CHEN J, You H, Lau G
    Rethinking 'Inactive Chronic Hepatitis B': should we treat patients with high HBsAg levels?
    Gut. 2025 Jul 23:gutjnl-2025-336373. doi: 10.1136/gutjnl-2025-336373.
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  6. GUILLOT A, Pose E
    Hepatocyte senescence in alcohol-associated hepatitis: epiphenomenon or disease-driving mechanism?
    Gut. 2025 Jul 17:gutjnl-2025-335271. doi: 10.1136/gutjnl-2025-335271.
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    June 2025
  7. TSENG TC, Huang SC, Pan MH, Liu CJ, et al
    Hepatitis B surface antigen level identifies patients with inactive chronic hepatitis B from Asia with HCC risk below surveillance threshold.
    Gut. 2025 Jun 20:gutjnl-2025-334911. doi: 10.1136/gutjnl-2025-334911.
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    May 2025
  8. LI H, Song M, Hylemon PB, Zhou H, et al
    LECT2-PHB2 axis: a new mechanistic insight and therapeutic opportunity in alcohol-associated hepatitis.
    Gut. 2025 May 13:gutjnl-2025-335259. doi: 10.1136/gutjnl-2025-335259.
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    April 2025
  9. ROTTELE F, Zollner A, Mogler C, Yuksel M, et al
    Characteristic immune cell interactions in livers of children with acute hepatitis revealed by spatial single-cell analysis identify a possible postacute sequel of COVID-19.
    Gut. 2025 Apr 5:gutjnl-2024-333880. doi: 10.1136/gutjnl-2024-333880.
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  10. LURJE I, Tacke F
    Immune pathology in paediatric acute hepatitis of unknown origin - uncovering the link to COVID-19.
    Gut. 2025 Apr 5:gutjnl-2024-334453. doi: 10.1136/gutjnl-2024-334453.
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  11. GLEESON D, Bornand R, Brownlee A, Dhaliwal H, et al
    British Society of Gastroenterology guidelines for diagnosis and management of autoimmune hepatitis.
    Gut. 2025 Apr 1:gutjnl-2024-333171. doi: 10.1136/gutjnl-2024-333171.
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    March 2025
  12. XU H, Wu Z, Qin J, Li X, et al
    Stressed hepatocyte sustains alcohol-associated hepatitis progression by producing leukocyte cell-derived chemotaxin 2.
    Gut. 2025 Mar 26:gutjnl-2024-334318. doi: 10.1136/gutjnl-2024-334318.
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  13. RODRIGO-TORRES D, Kilpatrick AM, Ferreira-Gonzalez S, Aird RE, et al
    Longitudinal paired liver biopsies and transcriptome profiling in alcohol-associated hepatitis reveal dynamic changes in cellular senescence.
    Gut. 2025 Mar 23:gutjnl-2024-334094. doi: 10.1136/gutjnl-2024-334094.
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    December 2024
  14. LAMPERTICO P, Anolli MP, Roulot D, Wedemeyer H, et al
    Antiviral therapy for chronic hepatitis delta: new insights from clinical trials and real-life studies.
    Gut. 2024 Dec 11:gutjnl-2024-332597. doi: 10.1136/gutjnl-2024-332597.
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    October 2024
  15. PAN DZ, Soulette CM, Aggarwal A, Han D, et al
    Effects of tenofovir disoproxil fumarate on intrahepatic viral burden and liver immune microenvironment in patients with chronic hepatitis B.
    Gut. 2024 Oct 8:gutjnl-2024-332526. doi: 10.1136/gutjnl-2024-332526.
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  16. LIU T, Li J, Yin X, Lu F, et al
    Establishment of enterically transmitted hepatitis virus animal models using lipid nanoparticle-based full-length viral genome RNA delivery system.
    Gut. 2024 Oct 1:gutjnl-2024-332784. doi: 10.1136/gutjnl-2024-332784.
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    September 2024
  17. BROL MJ, Canbay A, Trebicka J
    Alcohol-associated hepatitis: a neutrophile disease?
    Gut. 2024 Sep 24:gutjnl-2024-333222. doi: 10.1136/gutjnl-2024-333222.
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  18. MAK LY, Wooddell CI, Lenz O, Schluep T, et al
    Long-term hepatitis B surface antigen response after finite treatment of ARC-520 or JNJ-3989.
    Gut. 2024 Sep 12:gutjnl-2024-333026. doi: 10.1136/gutjnl-2024-333026.
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  19. FAN R, Zhao S, Niu J, Ma H, et al
    High accuracy model for HBsAg loss based on longitudinal trajectories of serum qHBsAg throughout long-term antiviral therapy.
    Gut. 2024;73:1725-1736.
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    July 2024
  20. VECCHI A, Rossi M, Tiezzi C, Fisicaro P, et al
    HBcrAg values may predict virological and immunological responses to pegIFN-alpha in NUC-suppressed HBeAg-negative chronic hepatitis B.
    Gut. 2024 Jul 20:gutjnl-2024-332290. doi: 10.1136/gutjnl-2024-332290.
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  21. KREIMEYER H, Gonzalez CG, Fondevila MF, Hsu CL, et al
    Faecal proteomics links neutrophil degranulation with mortality in patients with alcohol-associated hepatitis.
    Gut. 2024 Jul 20:gutjnl-2024-332730. doi: 10.1136/gutjnl-2024-332730.
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  22. BAUMERT T, Urbanek-Quaing M, Cornberg M
    Immunomodulation and entry inhibition: selgantolimod's double punch against hepatitis B virus.
    Gut. 2024 Jul 5:gutjnl-2024-332679. doi: 10.1136/gutjnl-2024-332679.
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  23. KAMAR N, Marion O, Abravanel F, Esposito L, et al
    Porcine-derived pancreatic enzyme replacement therapy: a cause of hepatitis E virus transmission?
    Gut. 2024 Jul 2:gutjnl-2024-332744. doi: 10.1136/gutjnl-2024-332744.
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    June 2024
  24. ZHOU J, Liu K, Pan Q
    Porcine-derived pancreatic enzyme replacement therapy linking to chronic hepatitis E: broad implications.
    Gut. 2024 Jun 12:gutjnl-2024-332975. doi: 10.1136/gutjnl-2024-332975.
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    May 2024
  25. FRERICKS N, Kinast V, Steinmann E
    Potential risk of porcine-derived pancreatic enzyme medication for the cross-species transmission of hepatitis E virus.
    Gut. 2024 May 31:gutjnl-2024-332577. doi: 10.1136/gutjnl-2024-332577.
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  26. VO-QUANG E, Pawlotsky JM
    'Unusual' HCV genotype subtypes: origin, distribution, sensitivity to direct-acting antiviral drugs and behaviour on antiviral treatment and retreatment.
    Gut. 2024 May 23:gutjnl-2024-332177. doi: 10.1136/gutjnl-2024-332177.
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  27. ROCA SUAREZ AA, Plissonnier ML, Grand X, Michelet M, et al
    TLR8 agonist selgantolimod regulates Kupffer cell differentiation status and impairs HBV entry into hepatocytes via an IL-6-dependent mechanism.
    Gut. 2024 May 2:gutjnl-2023-331396. doi: 10.1136/gutjnl-2023-331396.
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    April 2024
  28. THORNTON CS, Waddell BJ, Congly SE, Svishchuk J, et al
    Porcine-derived pancreatic enzyme replacement therapy may be linked to chronic hepatitis E virus infection in cystic fibrosis lung transplant recipients.
    Gut. 2024 Apr 15:gutjnl-2023-330602. doi: 10.1136/gutjnl-2023-330602.
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    January 2024
  29. HE T, Zhang D
    Non-linear association of baseline viral load with on-treatment hepatocellular carcinoma risk in chronic hepatitis B: still needs further discussion.
    Gut. 2024 Jan 22:gutjnl-2023-331443. doi: 10.1136/gutjnl-2023-331443.
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  30. Correction: Hepatitis C reference viruses highlight potent antibody responses and diverse viral functional interactions with neutralising antibodies.
    Gut. 2024;73:e1.
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  31. LIN C, Luo L, Xun Z, Zhu C, et al
    Novel function of MOTS-c in mitochondrial remodelling contributes to its antiviral role during HBV infection.
    Gut. 2024;73:338-349.
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    November 2023
  32. WANG Y, Li Q, Li C, Wang C, et al
    Chimeric antigen receptors of HBV envelope proteins inhibit hepatitis B surface antigen secretion.
    Gut. 2023 Nov 16:gutjnl-2023-330537. doi: 10.1136/gutjnl-2023-330537.
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  33. YU X, Gong Q, Yu D, Chen Y, et al
    Spatial transcriptomics reveals a low extent of transcriptionally active hepatitis B virus integration in patients with HBsAg loss.
    Gut. 2023 Nov 15:gutjnl-2023-330577. doi: 10.1136/gutjnl-2023-330577.
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    October 2023
  34. TESTONI B, Scholtes C, Plissonnier ML, Paturel A, et al
    Quantification of circulating HBV RNA expressed from intrahepatic cccDNA in untreated and NUC treated patients with chronic hepatitis B.
    Gut. 2023 Oct 25:gutjnl-2023-330644. doi: 10.1136/gutjnl-2023-330644.
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  35. CHOI WM, Kim GA, Choi J, Choi GH, et al
    Non-linear association of baseline viral load with on-treatment hepatocellular carcinoma risk in chronic hepatitis B.
    Gut. 2023 Oct 9:gutjnl-2023-330225. doi: 10.1136/gutjnl-2023-330225.
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  36. LIU Z, Lin C, Mao X, Guo C, et al
    Changing prevalence of chronic hepatitis B virus infection in China between 1973 and 2021: a systematic literature review and meta-analysis of 3740 studies and 231 million people.
    Gut. 2023 Oct 5:gutjnl-2023-330691. doi: 10.1136/gutjnl-2023-330691.
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    September 2023
  37. LE BERT N, Fisicaro P
    Enolase: a metabolic checkpoint behind diverse exhaustion stages of CD8+ T cells in chronic HBV and HCV.
    Gut. 2023 Sep 6:gutjnl-2023-330541. doi: 10.1136/gutjnl-2023-330541.
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    January 2023
  38. HENDRIKX T, Lang S, Rajcic D, Wang Y, et al
    Hepatic pIgR-mediated secretion of IgA limits bacterial translocation and prevents ethanol-induced liver disease in mice.
    Gut. 2023 Jan 23:gutjnl-2022-328265. doi: 10.1136/gutjnl-2022-328265.
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