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Articles published in
PLoS Pathog
    March 2024
  1. MATSUDA M, Hirai-Yuki A, Kotani O, Kataoka M, et al
    Loxapine inhibits replication of hepatitis A virus in vitro and in vivo by targeting viral protein 2C.
    PLoS Pathog. 2024;20:e1012091.
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  2. LI Y, Wu C, Lee J, Ning Q, et al
    Hepatitis B virus e antigen induces atypical metabolism and differentially regulates programmed cell deaths of macrophages.
    PLoS Pathog. 2024;20:e1012079.
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  3. KHALFI P, Denis Z, McKellar J, Merolla G, et al
    Comparative analysis of human, rodent and snake deltavirus replication.
    PLoS Pathog. 2024;20:e1012060.
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    February 2024
  4. BENDER D, Koulouri A, Wen X, Glitscher M, et al
    Guanylate-binding protein 1 acts as a pro-viral factor for the life cycle of hepatitis C virus.
    PLoS Pathog. 2024;20:e1011976.
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  5. ZHENG Y, Wang M, Yin J, Duan Y, et al
    Hepatitis B virus RNAs co-opt ELAVL1 for stabilization and CRM1-dependent nuclear export.
    PLoS Pathog. 2024;20:e1011999.
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    January 2024
  6. TSUKUDA S, Harris JM, Magri A, Balfe P, et al
    The N6-methyladenosine demethylase ALKBH5 regulates the hypoxic HBV transcriptome.
    PLoS Pathog. 2024;20:e1011917.
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    December 2023
  7. FENG J, Xu T, He M, Li J, et al
    NSUN2-mediated m5C modification of HBV RNA positively regulates HBV replication.
    PLoS Pathog. 2023;19:e1011808.
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  8. SO CW, Sourisseau M, Sarwar S, Evans MJ, et al
    Roles of epidermal growth factor receptor, claudin-1 and occludin in multi-step entry of hepatitis C virus into polarized hepatoma spheroids.
    PLoS Pathog. 2023;19:e1011887.
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    November 2023
  9. CARRIQUI-MADRONAL B, Sheldon J, Duven M, Stegmann C, et al
    The matrix metalloproteinase ADAM10 supports hepatitis C virus entry and cell-to-cell spread via its sheddase activity.
    PLoS Pathog. 2023;19:e1011759.
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    October 2023
  10. DRAVID P, Murthy S, Attia Z, Cassady C, et al
    Phenotype and fate of liver-resident CD8 T cells during acute and chronic hepacivirus infection.
    PLoS Pathog. 2023;19:e1011697.
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    September 2023
  11. SUBRAMANIAM S, Fares-Gusmao R, Sato S, Cullen JM, et al
    Distinct disease features of acute and persistent genotype 3 hepatitis E virus infection in immunocompetent and immunosuppressed Mongolian gerbils.
    PLoS Pathog. 2023;19:e1011664.
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    August 2023
  12. OHTA K, Ito M, Chida T, Nakashima K, et al
    Role of hepcidin upregulation and proteolytic cleavage of ferroportin 1 in hepatitis C virus-induced iron accumulation.
    PLoS Pathog. 2023;19:e1011591.
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  13. RAHEJA H, George B, Tripathi SK, Saha S, et al
    Hepatitis C virus non-structural proteins modulate cellular kinases for increased cytoplasmic abundance of host factor HuR and facilitate viral replication.
    PLoS Pathog. 2023;19:e1011552.
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  14. EWART G, Bobardt M, Bentzen BH, Yan Y, et al
    Post-infection treatment with the E protein inhibitor BIT225 reduces disease severity and increases survival of K18-hACE2 transgenic mice infected with a lethal dose of SARS-CoV-2.
    PLoS Pathog. 2023;19:e1011328.
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    July 2023
  15. PHAM MT, Lee JY, Ritter C, Thielemann R, et al
    Endosomal egress and intercellular transmission of hepatic ApoE-containing lipoproteins and its exploitation by the hepatitis C virus.
    PLoS Pathog. 2023;19:e1011052.
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  16. PIERCE DM, Buchanan FJT, Macrae FL, Mills JT, et al
    Thrombin cleavage of the hepatitis E virus polyprotein at multiple conserved locations is required for genome replication.
    PLoS Pathog. 2023;19:e1011529.
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    June 2023
  17. JU X, Yu Y, Ren W, Dong L, et al
    The PRMT5/WDR77 complex restricts hepatitis E virus replication.
    PLoS Pathog. 2023;19:e1011434.
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    May 2023
  18. ZHENG Y, Wang M, Li S, Bu Y, et al
    Hepatitis B virus hijacks TSG101 to facilitate egress via multiple vesicle bodies.
    PLoS Pathog. 2023;19:e1011382.
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    February 2023
  19. CHEN S, Harris M
    NS5A domain I antagonises PKR to facilitate the assembly of infectious hepatitis C virus particles.
    PLoS Pathog. 2023;19:e1010812.
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    November 2022
  20. MAZOUZ S, Salinas E, Bedard N, Filali A, et al
    Differential immune transcriptomic profiles between vaccinated and resolved HCV reinfected subjects.
    PLoS Pathog. 2022;18:e1010968.
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    October 2022
  21. ISKEN O, Pham MT, Schwanke H, Schlotthauer F, et al
    Characterization of a multipurpose NS3 surface patch coordinating HCV replicase assembly and virion morphogenesis.
    PLoS Pathog. 2022;18:e1010895.
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    August 2022
  22. HERVOUET K, Ferrie M, Ankavay M, Montpellier C, et al
    An Arginine-Rich Motif in the ORF2 capsid protein regulates the hepatitis E virus lifecycle and interactions with the host cell.
    PLoS Pathog. 2022;18:e1010798.
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  23. SHIRASAKI T, Feng H, Duyvesteyn HME, Fusco WG, et al
    Nonlytic cellular release of hepatitis A virus requires dual capsid recruitment of the ESCRT-associated Bro1 domain proteins HD-PTP and ALIX.
    PLoS Pathog. 2022;18:e1010543.
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    July 2022
  24. CARTWRIGHT HN, Barbeau DJ, Doyle JD, Klein E, et al
    Genetic diversity of collaborative cross mice enables identification of novel rift valley fever virus encephalitis model.
    PLoS Pathog. 2022;18:e1010649.
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  25. HONG X, Menne S, Hu J
    Constrained evolution of overlapping genes in viral host adaptation: Acquisition of glycosylation motifs in hepadnaviral precore/core genes.
    PLoS Pathog. 2022;18:e1010739.
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    June 2022
  26. HEUSS C, Rothhaar P, Burm R, Lee JY, et al
    A Hepatitis C virus genotype 1b post-transplant isolate with high replication efficiency in cell culture and its adaptation to infectious virus production in vitro and in vivo.
    PLoS Pathog. 2022;18:e1010472.
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  27. ISKEN O, Walther T, Wong-Dilworth L, Rehders D, et al
    Identification of NS2 determinants stimulating intrinsic HCV NS2 protease activity.
    PLoS Pathog. 2022;18:e1010644.
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  28. HONG X, Kawasawa YI, Menne S, Hu J, et al
    Host cell-dependent late entry step as determinant of Hepatitis B virus infection.
    PLoS Pathog. 2022;18:e1010633.
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  29. KIM ES, Zhou J, Zhang H, Marchetti A, et al
    Hepatitis B virus X protein counteracts high mobility group box 1 protein-mediated epigenetic silencing of covalently closed circular DNA.
    PLoS Pathog. 2022;18:e1010576.
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    May 2022
  30. HUM NR, Bourguet FA, Sebastian A, Lam D, et al
    MAVS mediates a protective immune response in the brain to Rift Valley fever virus.
    PLoS Pathog. 2022;18:e1010231.
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    March 2022
  31. DORNBRACK K, Beck J, Nassal M
    Relaxing the restricted structural dynamics in the human hepatitis B virus RNA encapsidation signal enables replication initiation in vitro.
    PLoS Pathog. 2022;18:e1010362.
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    February 2022
  32. ALZAHRANI N, Wu MJ, Sousa CF, Kalinina OV, et al
    SPCS1-Dependent E2-p7 processing determines HCV Assembly efficiency.
    PLoS Pathog. 2022;18:e1010310.
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    January 2022
  33. LIN J, Yin L, Xu XZ, Sun HC, et al
    Bay41-4109-induced aberrant polymers of hepatitis b capsid proteins are removed via STUB1-promoted p62-mediated macroautophagy.
    PLoS Pathog. 2022;18:e1010204.
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  34. OGEGA CO, Skinner NE, Flyak AI, Clark KE, et al
    B cell overexpression of FCRL5 and PD-1 is associated with low antibody titers in HCV infection.
    PLoS Pathog. 2022;18:e1010179.
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  35. SABARIEGOS R, Ortega-Prieto AM, Diaz-Martinez L, Grande-Perez A, et al
    Guanosine inhibits hepatitis C virus replication and increases indel frequencies, associated with altered intracellular nucleotide pools.
    PLoS Pathog. 2022;18:e1010210.
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    December 2021
  36. SAADI F, Chakravarty D, Kumar S, Kamble M, et al
    CD40L protects against mouse hepatitis virus-induced neuroinflammatory demyelination.
    PLoS Pathog. 2021;17:e1010059.
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    November 2021
  37. LIU H, Cheng J, Viswanathan U, Chang J, et al
    Amino acid residues at core protein dimer-dimer interface modulate multiple steps of hepatitis B virus replication and HBeAg biogenesis.
    PLoS Pathog. 2021;17:e1010057.
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    September 2021
  38. SUN L, Li Y, Misumi I, Gonzalez-Lopez O, et al
    IRF3-mediated pathogenicity in a murine model of human hepatitis A.
    PLoS Pathog. 2021;17:e1009960.
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  39. DANESH G, Virlogeux V, Ramiere C, Charre C, et al
    Quantifying transmission dynamics of acute hepatitis C virus infections in a heterogeneous population using sequence data.
    PLoS Pathog. 2021;17:e1009916.
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  40. WANG B, Zhu Y, Yu C, Zhang C, et al
    Hepatitis C virus induces oxidation and degradation of apolipoprotein B to enhance lipid accumulation and promote viral production.
    PLoS Pathog. 2021;17:e1009889.
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    August 2021
  41. BURCHILL MA, Salomon MP, Golden-Mason L, Wieland A, et al
    Single-cell transcriptomic analyses of T cells in chronic HCV-infected patients dominated by DAA-induced interferon signaling changes.
    PLoS Pathog. 2021;17:e1009799.
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  42. YUE L, Li C, Xu M, Wu M, et al
    Probing the spatiotemporal patterns of HBV multiplication reveals novel features of its subcellular processes.
    PLoS Pathog. 2021;17:e1009838.
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    July 2021
  43. LI Y, Luo G
    Human low-density lipoprotein receptor plays an important role in hepatitis B virus infection.
    PLoS Pathog. 2021;17:e1009722.
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  44. OLESEN CH, Augestad EH, Troise F, Bukh J, et al
    In vitro adaptation and characterization of attenuated hypervariable region 1 swap chimeras of hepatitis C virus.
    PLoS Pathog. 2021;17:e1009720.
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  45. YU T, Yang Q, Tian F, Chang H, et al
    Glycometabolism regulates hepatitis C virus release.
    PLoS Pathog. 2021;17:e1009746.
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    May 2021
  46. BAUDI I, Isogawa M, Moalli F, Onishi M, et al
    Interferon signaling suppresses the unfolded protein response and induces cell death in hepatocytes accumulating hepatitis B surface antigen.
    PLoS Pathog. 2021;17:e1009228.
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    April 2021
  47. SCHOBEL A, Nguyen-Dinh V, Schumann GG, Herker E, et al
    Hepatitis C virus infection restricts human LINE-1 retrotransposition in hepatoma cells.
    PLoS Pathog. 2021;17:e1009496.
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    March 2021
  48. HARTLAGE AS, Dravid P, Walker CM, Kapoor A, et al
    Adenovirus-vectored T cell vaccine for hepacivirus shows reduced effectiveness against a CD8 T cell escape variant in rats.
    PLoS Pathog. 2021;17:e1009391.
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    January 2021
  49. WELLS AI, Grimes KA, Kim K, Branche E, et al
    Human FcRn expression and Type I Interferon signaling control Echovirus 11 pathogenesis in mice.
    PLoS Pathog. 2021;17:e1009252.
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