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Articles published in
PLoS Pathog
    February 2026
  1. LIU HN, Kim E, Sun N, Wang Z, et al
    Detection and characterization of Hepatitis B virus double-stranded linear DNA-derived covalently closed circular DNA in chronic hepatitis B patients.
    PLoS Pathog. 2026;22:e1013999.
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  2. PAESEN GC, Chapman NS, Westover JB, McMillen CM, et al
    Structural basis for recognition of Rift Valley fever virus Gn protein by a human neutralizing monoclonal antibody with a kappa light chain.
    PLoS Pathog. 2026;22:e1013926.
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    January 2026
  3. MATSUZAWA K, Ekimoto T, Kobayashi C, Shionoya K, et al
    Structural mapping of NTCP distinguishes its dual functionality as a hepatitis B virus receptor and bile acid transporter.
    PLoS Pathog. 2026;22:e1013824.
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    December 2025
  4. WANG Y, Wu S, Li X, Qiao L, et al
    Antiviral and immune modulatory activities of STING agonists in a mouse model of persistent hepatitis B virus infection.
    PLoS Pathog. 2025;21:e1013709.
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  5. GUNAWARDENE CD, Pandey I, Chatterjee S, Penaflor-Tellez Y, et al
    Heterologous expression of HCoV-HKU1 ORF 7b by mouse hepatitis virus protects against severe disease during murine infection.
    PLoS Pathog. 2025;21:e1013148.
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  6. WANG Y, Murai K, Ishida A, Kawasaki N, et al
    Netrin-1 inhibits the attachment and internalization of Hepatitis B virus for hepatocyte infection.
    PLoS Pathog. 2025;21:e1013776.
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    November 2025
  7. MEESTER M, Valenzuela Agui C, Tobias TJ, Guinat C, et al
    Zoonotic hepatitis E virus spreads through environmental routes in pig herds-A phylodynamic analysis.
    PLoS Pathog. 2025;21:e1013710.
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    September 2025
  8. THORSELIUS CE, Kok A, Fahnoe U, Wolfisberg R, et al
    In vivo and in vitro recombinant systems of a novel variant demonstrate cross-reactive neutralization for the HCV model virus, Norway rat hepacivirus.
    PLoS Pathog. 2025;21:e1013127.
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  9. MEHNERT AK, Stegmaier S, Ramirez Alvarez C, Toprak E, et al
    The hepatitis E virus capsid protein ORF2 counteracts cell-intrinsic antiviral responses to enable persistent replication in cell culture.
    PLoS Pathog. 2025;21:e1013516.
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  10. SCHWOERER MP, Carver S, Lin AE, Liu J, et al
    Receptor transporter protein 4 (RTP4)-mediated repression of hepatitis C virus replication in mouse cells.
    PLoS Pathog. 2025;21:e1013412.
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    August 2025
  11. XU Z, Zhao K, Wang J, Zhang L, et al
    Screening of different species reveals cat hepatocytes support HBV infection.
    PLoS Pathog. 2025;21:e1013390.
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    April 2025
  12. ZHAO L, Hall M, Giridhar P, Ghafari M, et al
    Genetically distinct within-host subpopulations of hepatitis C virus persist after Direct-Acting Antiviral treatment failure.
    PLoS Pathog. 2025;21:e1012959.
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    March 2025
  13. SOERENSEN A, Popovic F, Olesen CH, Mendez BL, et al
    Selection and characterization of a broadly neutralizing class of HCV anti-E2 VH1-69 antibodies.
    PLoS Pathog. 2025;21:e1012428.
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    February 2025
  14. ZHANG H, Long Q, Liu Y, Marchetti AL, et al
    Host 3' flap endonuclease Mus81 plays a critical role in trimming the terminal redundancy of hepatitis B virus relaxed circular DNA during covalently closed circular DNA formation.
    PLoS Pathog. 2025;21:e1012918.
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  15. HSIEH CL, Chang LY, Chen PJ, Yeh SH, et al
    HBV polymerase recruits the phosphatase PP1 to dephosphorylate HBc-Ser170 to complete encapsidation.
    PLoS Pathog. 2025;21:e1012905.
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  16. BRADLEY DP, Valkner CJ, Li Q, Gasonoo M, et al
    Discovery of bimodal hepatitis B virus ribonuclease H and capsid assembly inhibitors.
    PLoS Pathog. 2025;21:e1012920.
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    January 2025
  17. ZHAO K, Wang J, Wang Z, Wang M, et al
    Hepatitis B virus hijacks MRE11-RAD50-NBS1 complex to form its minichromosome.
    PLoS Pathog. 2025;21:e1012824.
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  18. YU L, Chang H, Xie W, Zheng Y, et al
    Manganese is a potent inducer of lysosomal activity that inhibits de novo HBV infection.
    PLoS Pathog. 2025;21:e1012800.
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  19. ZHANG M, Mouzannar K, Zhang Z, Teraoka Y, et al
    Hepatitis B virus genotypes A1 and A2 have distinct replication phenotypes due to polymorphisms in the HBx gene.
    PLoS Pathog. 2025;21:e1012803.
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  20. QIU Q, He Z, Liu J, Xu H, et al
    Homeobox protein MSX-1 restricts hepatitis B virus by promoting ubiquitin-independent proteasomal degradation of HBx protein.
    PLoS Pathog. 2025;21:e1012897.
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    October 2024
  21. LOPEZ-SCARIM J, Mendoza D, Nambiar SM, Billerbeck E, et al
    CD4+ T cell help during early acute hepacivirus infection is critical for viral clearance and the generation of a liver-homing CD103+CD49a+ effector CD8+ T cell subset.
    PLoS Pathog. 2024;20:e1012615.
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    September 2024
  22. REICHERT I, Lee JY, Weber L, Fuh MM, et al
    The triglyceride-synthesizing enzyme diacylglycerol acyltransferase 2 modulates the formation of the hepatitis C virus replication organelle.
    PLoS Pathog. 2024;20:e1012509.
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  23. SHEN S, Cai D, Liang H, Zeng G, et al
    NEDD4 family ubiquitin ligase AIP4 interacts with Alix to enable HBV naked capsid egress in an Alix ubiquitination-independent manner.
    PLoS Pathog. 2024;20:e1012485.
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    June 2024
  24. GRIESMAN T, McMillen CM, Negatu SG, Hulahan JJ, et al
    The lipopeptide Pam3CSK4 inhibits Rift Valley fever virus infection and protects from encephalitis.
    PLoS Pathog. 2024;20:e1012343.
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    May 2024
  25. YADAV KK, Boley PA, Laocharoensuk T, Khatiwada S, et al
    Infectious hepatitis E virus is associated with the mature sperm head.
    PLoS Pathog. 2024;20:e1012240.
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  26. CAMPS G, Maestro S, Torella L, Herrero D, et al
    Protective role of RIPK1 scaffolding against HDV-induced hepatocyte cell death and the significance of cytokines in mice.
    PLoS Pathog. 2024;20:e1011749.
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    March 2024
  27. MATSUDA M, Hirai-Yuki A, Kotani O, Kataoka M, et al
    Loxapine inhibits replication of hepatitis A virus in vitro and in vivo by targeting viral protein 2C.
    PLoS Pathog. 2024;20:e1012091.
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  28. LI Y, Wu C, Lee J, Ning Q, et al
    Hepatitis B virus e antigen induces atypical metabolism and differentially regulates programmed cell deaths of macrophages.
    PLoS Pathog. 2024;20:e1012079.
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  29. KHALFI P, Denis Z, McKellar J, Merolla G, et al
    Comparative analysis of human, rodent and snake deltavirus replication.
    PLoS Pathog. 2024;20:e1012060.
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  30. PETRACCIONE K, Ali MGH, Cyr N, Wahba HM, et al
    An LIR motif in the Rift Valley fever virus NSs protein is critical for the interaction with LC3 family members and inhibition of autophagy.
    PLoS Pathog. 2024;20:e1012093.
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    February 2024
  31. BENDER D, Koulouri A, Wen X, Glitscher M, et al
    Guanylate-binding protein 1 acts as a pro-viral factor for the life cycle of hepatitis C virus.
    PLoS Pathog. 2024;20:e1011976.
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  32. ZHENG Y, Wang M, Yin J, Duan Y, et al
    Hepatitis B virus RNAs co-opt ELAVL1 for stabilization and CRM1-dependent nuclear export.
    PLoS Pathog. 2024;20:e1011999.
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    January 2024
  33. TSUKUDA S, Harris JM, Magri A, Balfe P, et al
    The N6-methyladenosine demethylase ALKBH5 regulates the hypoxic HBV transcriptome.
    PLoS Pathog. 2024;20:e1011917.
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    December 2023
  34. FENG J, Xu T, He M, Li J, et al
    NSUN2-mediated m5C modification of HBV RNA positively regulates HBV replication.
    PLoS Pathog. 2023;19:e1011808.
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  35. SO CW, Sourisseau M, Sarwar S, Evans MJ, et al
    Roles of epidermal growth factor receptor, claudin-1 and occludin in multi-step entry of hepatitis C virus into polarized hepatoma spheroids.
    PLoS Pathog. 2023;19:e1011887.
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    November 2023
  36. CARRIQUI-MADRONAL B, Sheldon J, Duven M, Stegmann C, et al
    The matrix metalloproteinase ADAM10 supports hepatitis C virus entry and cell-to-cell spread via its sheddase activity.
    PLoS Pathog. 2023;19:e1011759.
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    October 2023
  37. DRAVID P, Murthy S, Attia Z, Cassady C, et al
    Phenotype and fate of liver-resident CD8 T cells during acute and chronic hepacivirus infection.
    PLoS Pathog. 2023;19:e1011697.
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    September 2023
  38. SUBRAMANIAM S, Fares-Gusmao R, Sato S, Cullen JM, et al
    Distinct disease features of acute and persistent genotype 3 hepatitis E virus infection in immunocompetent and immunosuppressed Mongolian gerbils.
    PLoS Pathog. 2023;19:e1011664.
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