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Articles published in
Proc Natl Acad Sci U S A
    September 2026
  1. LIU X, Shrestha SK, Edwards YJK, Filippova N, et al
    HuB/HuR inhibition decreases HPV E6 and E7 proteins, stabilizes p53, and induces integrated stress to impair cervical cancer cell growth.
    Proc Natl Acad Sci U S A. 2026;123:e2401248123.
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    August 2026
  2. MADASU C, Sirupangi T, Herrera GJ, Bohren KM, et al
    Identification of potent inhibitors of JUN N-terminal kinases for treatment of endometriosis and associated pain.
    Proc Natl Acad Sci U S A. 2026;123:e2607561123.
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    June 2026
  3. LI R, Huang X, Chen Y, Chen X, et al
    GREM1/FGFR1-activated myofibroblasts induce immunosuppression and accelerate metastasis in high-grade serous ovarian cancer.
    Proc Natl Acad Sci U S A. 2026;123:e2529786123.
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  4. RIETZ A, Kumari L, Koirala A, Pelletier S, et al
    Covalent inhibitors of human papillomavirus type 16 E6 protein restore p53 function and suppress growth of HPV-driven tumors in vivo.
    Proc Natl Acad Sci U S A. 2026;123:e2606213123.
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    May 2026
  5. PARK SK, Lee J, Park SJ, Kim YN, et al
    Functional dissection of SPOP at the amino acid level reveals a comprehensive functional landscape of variants during tumorigenesis.
    Proc Natl Acad Sci U S A. 2026;123:e2523210123.
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  6. JIAO X, Li Z, Tang Z, Xu J, et al
    MCM8-9 helicase activity protects primordial germ cell development to prevent premature ovarian insufficiency.
    Proc Natl Acad Sci U S A. 2026;123:e2535910123.
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  7. HAN YJ, Zhang J, Shariff M, Wu S, et al
    Regulation of antiviral and antitumor immunity by the BRCA1 pseudogene in human cancers.
    Proc Natl Acad Sci U S A. 2026;123:e2528911123.
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    February 2026
  8. HARTWICH TMP, Choi S, Hwang A, Bellone S, et al
    Integrated mutational landscape analysis of endometrial stromal sarcoma.
    Proc Natl Acad Sci U S A. 2026;123:e2531105123.
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    December 2025
  9. PARKS SE, Tang S, Unser AC, Bhonsley AL, et al
    TGFBR2 coordinates the endometrial response to estrogen, regulating endometrial hyperplasia and fertility.
    Proc Natl Acad Sci U S A. 2025;122:e2518507122.
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  10. LI Q, Yu H, Ling D, Zhou J, et al
    Modulation of the PGRMC1/NLRP7/HLA-C axis by autophagy is linked to both spontaneous preterm birth and gestational choriocarcinoma.
    Proc Natl Acad Sci U S A. 2025;122:e2509798122.
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  11. PARASKEVAIDI M, Raglan O, McKenzie J, Xiang Y, et al
    Lipidomic profiling of endometrial cancer using desorption electrospray ionization mass spectrometry imaging.
    Proc Natl Acad Sci U S A. 2025;122:e2522839122.
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    November 2025
  12. MARQUARDT RM, Grimm SA, Wu SP, Lais PF, et al
    Serum response factor is essential for endometrial function and prevention of inflammatory fibrosis.
    Proc Natl Acad Sci U S A. 2025;122:e2510060122.
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    September 2025
  13. CHOWDHURY SR, Parikh CN, Kaur AN, DeMarco KD, et al
    PPT1 is a negative regulator of STING signaling in cancer cells and its inhibition reactivates immune surveillance in cold tumors.
    Proc Natl Acad Sci U S A. 2025;122:e2514948122.
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  14. ALENCAR GF, Mohamed AO, Burnett MG, Jean SS, et al
    Triple checkpoint blockade of PD-1, Tim-3, and Lag-3 enhances adoptive T cell immunotherapy in a mouse model of ovarian cancer.
    Proc Natl Acad Sci U S A. 2025;122:e2419888122.
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  15. NUOVO GJ, Tili E, Croce CM
    Loss of ICOSL expression in the progression to cervical carcinoma.
    Proc Natl Acad Sci U S A. 2025;122:e2509425122.
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    July 2025
  16. FREDERICK J, Virk RKA, Ye IC, Almassalha LM, et al
    Leveraging chromatin packing domains to target chemoevasion in vivo.
    Proc Natl Acad Sci U S A. 2025;122:e2425319122.
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  17. SUN R, Jiang P, Wang Z, Yan B, et al
    DNA2 protein destruction dictates DNA hyperexcision, cGAS-STING activation, and innate immune response in CDK12-deregulated cancers.
    Proc Natl Acad Sci U S A. 2025;122:e2413732122.
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    June 2025
  18. TIEN JC, Zhai Y, Wu R, Zhang Y, et al
    Defining CDK12 as a tumor suppressor and therapeutic target in mouse models of tubo-ovarian high-grade serous carcinoma.
    Proc Natl Acad Sci U S A. 2025;122:e2426909122.
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  19. LAMPERIS SM, McMahon KM, Calvert AE, Rink JS, et al
    CRISPR screen reveals a simultaneous targeted mechanism to reduce cancer cell selenium and increase lipid oxidation to induce ferroptosis.
    Proc Natl Acad Sci U S A. 2025;122:e2502876122.
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    February 2025
  20. RIZO JA, Ahmad V, Pru JM, Winuthayanon S, et al
    Uterine organoids reveal insights into epithelial specification and plasticity in development and disease.
    Proc Natl Acad Sci U S A. 2025;122:e2422694122.
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    December 2024
  21. ZHAI G, Niu Z, Jiang Z, Zhao F, et al
    DPF2 reads histone lactylation to drive transcription and tumorigenesis.
    Proc Natl Acad Sci U S A. 2024;121:e2421496121.
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    November 2024
  22. RAVINDRANATHAN R, Somuncu O, da Costa AABA, Mukkavalli S, et al
    PARG inhibitor sensitivity correlates with accumulation of single-stranded DNA gaps in preclinical models of ovarian cancer.
    Proc Natl Acad Sci U S A. 2024;121:e2413954121.
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  23. NACIRI I, Liang M, Yang Y, Karner H, et al
    Loss of XIST lncRNA unlocks stemness and cellular plasticity in ovarian cancer.
    Proc Natl Acad Sci U S A. 2024;121:e2418096121.
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  24. ZHANG Z, Yu R, Shi Q, Wu ZJ, et al
    COX15 deficiency causes oocyte ferroptosis.
    Proc Natl Acad Sci U S A. 2024;121:e2406174121.
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    October 2024
  25. ROLLIN FG, Patel SA, McCachren SS
    Contextualizing racial associations in gene expression in patients with uterine serous carcinoma.
    Proc Natl Acad Sci U S A. 2024;121:e2418977121.
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  26. KIM JJ, Simon M, Fleming G
    Reply to Rollin et al.: Clarifying the multifactorial origins of racial disparities in uterine serous carcinoma.
    Proc Natl Acad Sci U S A. 2024;121:e2419163121.
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  27. ZHOU W, Van Sinderen M, Rainczuk K, Menkhorst E, et al
    Dysregulated miR-124-3p in endometrial epithelial cells reduces endometrial receptivity by altering polarity and adhesion.
    Proc Natl Acad Sci U S A. 2024;121:e2401071121.
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    September 2024
  28. HENLON Y, Panir K, McIntyre I, Hogg C, et al
    Single-cell analysis identifies distinct macrophage phenotypes associated with prodisease and proresolving functions in the endometriotic niche.
    Proc Natl Acad Sci U S A. 2024;121:e2405474121.
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  29. PELAYO P, Hussain FA, Werlang CA, Wu CM, et al
    Prevotella are major contributors of sialidases in the human vaginal microbiome.
    Proc Natl Acad Sci U S A. 2024;121:e2400341121.
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    August 2024
  30. FOLEY KG, Adli M, Kim JJ
    Single-nuclei sequencing of uterine serous carcinoma reveals racial differences in immune signaling.
    Proc Natl Acad Sci U S A. 2024;121:e2402998121.
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    June 2024
  31. YAN W
    Deciphering the code: Advancing therapies for endometriosis and cancer with DNA-encoded drug discovery.
    Proc Natl Acad Sci U S A. 2024;121:e2407555121.
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    May 2024
  32. MADASU C, Liao Z, Parks SE, Sharma KL, et al
    Identification of potent pan-ephrin receptor kinase inhibitors using DNA-encoded chemistry technology.
    Proc Natl Acad Sci U S A. 2024;121:e2322934121.
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  33. NAN Y, Wu X, Luo Q, Chang W, et al
    OTUB2 silencing promotes ovarian cancer via mitochondrial metabolic reprogramming and can be synthetically targeted by CA9 inhibition.
    Proc Natl Acad Sci U S A. 2024;121:e2315348121.
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    April 2024
  34. BELLONE S, Jeong K, Halle MK, Krakstad C, et al
    Integrated mutational landscape analysis of poorly differentiated high-grade neuroendocrine carcinoma of the uterine cervix.
    Proc Natl Acad Sci U S A. 2024;121:e2321898121.
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    March 2024
  35. LOWY DR
    Harald zur Hausen (1936 to 2023): Discoverer of human papillomavirus infection as the main cause of cervical cancer.
    Proc Natl Acad Sci U S A. 2024;121:e2400517121.
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  36. HAO L, Boehnke N, Elledge SK, Harzallah NS, et al
    Targeting and monitoring ovarian cancer invasion with an RNAi and peptide delivery system.
    Proc Natl Acad Sci U S A. 2024;121:e2307802121.
    >> Share


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