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Gastric Cancer

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Articles published in
    August 2022
  1. DAWSON RE, Deswaerte V, West AC, Tang K, et al
    STAT3-mediated upregulation of the AIM2 DNA sensor links innate immunity with cell migration to promote epithelial tumourigenesis.
    Gut. 2022;71:1515-1531.
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    July 2022
  2. WANG Z, Han W, Xue F, Zhao Y, et al
    Nationwide gastric cancer prevention in China, 2021-2035: a decision analysis on effect, affordability and cost-effectiveness optimisation.
    Gut. 2022 Jul 28. pii: gutjnl-2021-325948. doi: 10.1136/gutjnl-2021-325948.
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  3. HO SWT, Sheng T, Xing M, Ooi WF, et al
    Regulatory enhancer profiling of mesenchymal-type gastric cancer reveals subtype-specific epigenomic landscapes and targetable vulnerabilities.
    Gut. 2022 Jul 11. pii: gutjnl-2021-326483. doi: 10.1136/gutjnl-2021-326483.
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    Gut check: can other microbes or communities phenocopy H. pylori's early gastric pathology?
    Gut. 2022;71:1241-1242.
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  5. SUNDAR R, Huang KK, Kumar V, Ramnarayanan K, et al
    Epigenetic promoter alterations in GI tumour immune-editing and resistance to immune checkpoint inhibition.
    Gut. 2022;71:1277-1288.
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  6. KWON SK, Park JC, Kim KH, Yoon J, et al
    Human gastric microbiota transplantation recapitulates premalignant lesions in germ-free mice.
    Gut. 2022;71:1266-1276.
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    June 2022
  7. TONG Y, Cheng PSW, Or CS, Yue SSK, et al
    Escape from cell-cell and cell-matrix adhesion dependence underscores disease progression in gastric cancer organoid models.
    Gut. 2022 Jun 15. pii: gutjnl-2022-327121. doi: 10.1136/gutjnl-2022-327121.
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  8. CALDWELL B, Meyer AR, Weis JA, Engevik AC, et al
    Chief cell plasticity is the origin of metaplasia following acute injury in the stomach mucosa.
    Gut. 2022;71:1068-1077.
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    April 2022
  9. QUANTE M, Wang TC, Bass AJ
    Adenocarcinoma of the oesophagus: is it gastric cancer?
    Gut. 2022 Apr 1. pii: gutjnl-2022-327096. doi: 10.1136/gutjnl-2022-327096.
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    March 2022
  10. DONG X, Song S, Li Y, Fan Y, et al
    Loss of ARID1A activates mTOR signaling and SOX9 in gastric adenocarcinoma-rationale for targeting ARID1A deficiency.
    Gut. 2022;71:467-478.
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    December 2021
  11. SONG S, Chen Q, Li Y, Lei G, et al
    Targeting cancer stem cells with a pan-BCL-2 inhibitor in preclinical and clinical settings in patients with gastroesophageal carcinoma.
    Gut. 2021;70:2238-2248.
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    November 2021
  12. ZENG R, Sha W, Wang J, Zhuo Z, et al
    Evaluation of proton pump inhibitors and risks of gastric cancer.
    Gut. 2021 Nov 26. pii: gutjnl-2021-326291. doi: 10.1136/gutjnl-2021-326291.
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  13. ARNOLD M, Morgan E, Bardot A, Rutherford MJ, et al
    International variation in oesophageal and gastric cancer survival 2012-2014: differences by histological subtype and stage at diagnosis (an ICBP SURVMARK-2 population-based study).
    Gut. 2021 Nov 25. pii: gutjnl-2021-325266. doi: 10.1136/gutjnl-2021-325266.
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  14. LIU X, Chen T, Cheng J, Gao P, et al
    Endoscopic transmural route for dissection of gastric submucosal tumors with extraluminal growth: experience in two cases.
    Gut. 2021;70:2052-2054.
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  15. HAO D, He S, Harada K, Pizzi MP, et al
    Integrated genomic profiling and modelling for risk stratification in patients with advanced oesophagogastric adenocarcinoma.
    Gut. 2021;70:2055-2065.
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    October 2021
  16. MATSUO J, Douchi D, Myint K, Mon NN, et al
    Iqgap3-Ras axis drives stem cell proliferation in the stomach corpus during homoeostasis and repair.
    Gut. 2021;70:1833-1846.
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    September 2021
  17. RINKE A, Auernhammer CJ, Bodei L, Kidd M, et al
    Treatment of advanced gastroenteropancreatic neuroendocrine neoplasia, are we on the way to personalised medicine?
    Gut. 2021;70:1768-1781.
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  18. SMYTH EC, Vlachogiannis G, Hedayat S, Harbery A, et al
    EGFR amplification and outcome in a randomised phase III trial of chemotherapy alone or chemotherapy plus panitumumab for advanced gastro-oesophageal cancers.
    Gut. 2021;70:1632-1641.
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    August 2021
  19. ARAI J, Niikura R, Hayakawa Y, Aoki T, et al
    OLGIM staging and proton pump inhibitor use predict the risk of gastric cancer.
    Gut. 2021 Aug 3. pii: gutjnl-2021-325551. doi: 10.1136/gutjnl-2021-325551.
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    July 2021
  20. PATEL J, Berezowski I, Janapala RN, Pourmand A, et al
    Proton pump inhibitors and gastric cancer: a population-based cohort study.
    Gut. 2021 Jul 14. pii: gutjnl-2021-325385. doi: 10.1136/gutjnl-2021-325385.
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  21. ABRAHAMI D, McDonald EG, Schnitzer ME, Barkun AN, et al
    Proton pump inhibitors and risk of gastric cancer: population-based cohort study.
    Gut. 2021 Jul 5. pii: gutjnl-2021-325097. doi: 10.1136/gutjnl-2021-325097.
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  22. YAMAO K, Kitano M, Chiba Y, Ogura T, et al
    Endoscopic placement of covered versus uncovered self-expandable metal stents for palliation of malignant gastric outlet obstruction.
    Gut. 2021;70:1244-1252.
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    May 2021
  23. SUNDAR R, Barr Kumarakulasinghe N, Huak Chan Y, Yoshida K, et al
    Machine-learning model derived gene signature predictive of paclitaxel survival benefit in gastric cancer: results from the randomised phase III SAMIT trial.
    Gut. 2021 May 12. pii: gutjnl-2021-324060. doi: 10.1136/gutjnl-2021-324060.
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  24. SEO SI, Park CH, You SC, Kim JY, et al
    Association between proton pump inhibitor use and gastric cancer: a population-based cohort study using two different types of nationwide databases in Korea.
    Gut. 2021 May 11. pii: gutjnl-2020-323845. doi: 10.1136/gutjnl-2020-323845.
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  25. LEE JWJ, Zhu F, Srivastava S, Tsao SK, et al
    Severity of gastric intestinal metaplasia predicts the risk of gastric cancer: a prospective multicentre cohort study (GCEP).
    Gut. 2021 May 11. pii: gutjnl-2021-324057. doi: 10.1136/gutjnl-2021-324057.
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    March 2021
  26. LO CH, Kwon S, Wang L, Polychronidis G, et al
    Periodontal disease, tooth loss, and risk of oesophageal and gastric adenocarcinoma: a prospective study.
    Gut. 2021;70:620-621.
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  27. ZHANG M, Hu S, Min M, Ni Y, et al
    Dissecting transcriptional heterogeneity in primary gastric adenocarcinoma by single cell RNA sequencing.
    Gut. 2021;70:464-475.
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    February 2021
    Gastric biopsies in the assessment and management of patients at risk of gastric adenocarcinoma.
    Gut. 2021;70:431-432.
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  29. CHEN R, Liu Y, Song G, Li B, et al
    Effectiveness of one-time endoscopic screening programme in prevention of upper gastrointestinal cancer in China: a multicentre population-based cohort study.
    Gut. 2021;70:251-260.
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  30. TAKENAKA K, Kimura M, Ohtsuka K
    Colonic strictures mimicking Crohn's disease.
    Gut. 2021;70:233-387.
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    January 2021
  31. AJANI JA, Xu Y, Huo L, Wang R, et al
    YAP1 mediates gastric adenocarcinoma peritoneal metastases that are attenuated by YAP1 inhibition.
    Gut. 2021;70:55-66.
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    November 2020
  32. SUNDAR R, Liu DH, Hutchins GG, Slaney HL, et al
    Spatial profiling of gastric cancer patient-matched primary and locoregional metastases reveals principles of tumour dissemination.
    Gut. 2020 Nov 23. pii: gutjnl-2020-320805. doi: 10.1136/gutjnl-2020-320805.
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    October 2020
  33. SO JBY, Kapoor R, Zhu F, Koh C, et al
    Development and validation of a serum microRNA biomarker panel for detecting gastric cancer in a high-risk population.
    Gut. 2020 Oct 7. pii: gutjnl-2020-322065. doi: 10.1136/gutjnl-2020-322065.
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  34. LIOU JM, Malfertheiner P, Lee YC, Sheu BS, et al
    Screening and eradication of Helicobacter pylori for gastric cancer prevention: the Taipei global consensus.
    Gut. 2020 Oct 1. pii: gutjnl-2020-322368. doi: 10.1136/gutjnl-2020-322368.
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  35. MARCOS P, Brito-Goncalves G, Libanio D, Pita I, et al
    Endoscopic grading of gastric intestinal metaplasia on risk assessment for early gastric neoplasia: can we replace histology assessment also in the West?
    Gut. 2020;69:1762-1768.
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  36. KRISHNAN V, Lim DXE, Hoang PM, Srivastava S, et al
    DNA damage signalling as an anti-cancer barrier in gastric intestinal metaplasia.
    Gut. 2020;69:1738-1749.
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    September 2020
  37. DIXON K, Senz J, Kaurah P, Huntsman DG, et al
    Rare APC promoter 1B variants in gastric cancer kindreds unselected for fundic gland polyposis.
    Gut. 2020 Sep 7. pii: gutjnl-2020-321990. doi: 10.1136/gutjnl-2020-321990.
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  38. BANKS M, Uedo N, Bhandari P, Gotoda T, et al
    EMR achieves similar oncological outcomes as ESD for gastric neoplasia of <1cm, requiring less expertise, training and time.
    Gut. 2020;69:1.
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  39. SHAHIDI N, Bourke MJ
    ESD, not EMR, should be the first-line therapy for early gastric neoplasia.
    Gut. 2020;69:1-2.
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  40. GHISA M, Rugge M, Fassan M, Farinati F, et al
    There is much more to rely on histology than the sole endoscopy tells us.
    Gut. 2020;69:1.
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    August 2020
  41. MURAKAMI D, Yamato M, Amano Y, Tada T, et al
    Challenging detection of hard-to-find gastric cancers with artificial intelligence-assisted endoscopy.
    Gut. 2020 Aug 18. pii: gutjnl-2020-322453. doi: 10.1136/gutjnl-2020-322453.
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  42. CHIANG TH, Chang WJ, Chen SL, Yen AM, et al
    Mass eradication of Helicobacter pylori to reduce gastric cancer incidence and mortality: a long-term cohort study on Matsu Islands.
    Gut. 2020 Aug 13. pii: gutjnl-2020-322200. doi: 10.1136/gutjnl-2020-322200.
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    June 2020
  43. ARNOLD M, Ferlay J, van Berge Henegouwen MI, Soerjomataram I, et al
    Global burden of oesophageal and gastric cancer by histology and subsite in 2018.
    Gut. 2020 Jun 30. pii: gutjnl-2020-321600. doi: 10.1136/gutjnl-2020-321600.
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  44. BORNSCHEIN J, Rugge M
    Bright future for endoscopy: the new frontier of gastric cancer secondary prevention.
    Gut. 2020 Jun 12. pii: gutjnl-2020-321570. doi: 10.1136/gutjnl-2020-321570.
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  45. HATTA W, Tsuji Y, Yoshio T, Kakushima N, et al
    Prediction model of bleeding after endoscopic submucosal dissection for early gastric cancer: BEST-J score.
    Gut. 2020 Jun 4. pii: gutjnl-2019-319926. doi: 10.1136/gutjnl-2019-319926.
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  46. OOI WF, Nargund AM, Lim KJ, Zhang S, et al
    Integrated paired-end enhancer profiling and whole-genome sequencing reveals recurrent CCNE1 and IGF2 enhancer hijacking in primary gastric adenocarcinoma.
    Gut. 2020;69:1039-1052.
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    April 2020
  47. XIONG J, Wang Y, Chen G, Jin L, et al
    Proton pump inhibitors and the risk of gallbladder cancer: a hospital-based case-control study.
    Gut. 2020 Apr 9. pii: gutjnl-2020-321052. doi: 10.1136/gutjnl-2020-321052.
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  48. YOSHIDA N, Doyama H, Yano T, Horimatsu T, et al
    Early gastric cancer detection in high-risk patients: a multicentre randomised controlled trial on the effect of second-generation narrow band imaging.
    Gut. 2020 Apr 2. pii: gutjnl-2019-319631. doi: 10.1136/gutjnl-2019-319631.
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    March 2020
  49. FORD AC, Yuan Y, Moayyedi P
    Helicobacter pylori eradication therapy to prevent gastric cancer: systematic review and meta-analysis.
    Gut. 2020 Mar 23. pii: gutjnl-2020-320839. doi: 10.1136/gutjnl-2020-320839.
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  50. KOLB JM, Leong S, Westbrook LM, Patel SG, et al
    Aggressive case of early onset gastric cancer; identifying the knowledge gap.
    Gut. 2020 Mar 11. pii: gutjnl-2019-320453. doi: 10.1136/gutjnl-2019-320453.
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  51. YAMAJI Y, Hirata Y
    Treatment for Helicobacter pylori appears to reduce the incidence of gastric cancer: eradication effect or screening effect?
    Gut. 2020;69:605-606.
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    February 2020
  52. MAEDA M, Takeshima H, Iida N, Hattori N, et al
    Cancer cell niche factors secreted from cancer-associated fibroblast by loss of H3K27me3.
    Gut. 2020;69:243-251.
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    January 2020
  53. ARNOLD M, Park JY, Camargo MC, Lunet N, et al
    Is gastric cancer becoming a rare disease? A global assessment of predicted incidence trends to 2035.
    Gut. 2020 Jan 30. pii: gutjnl-2019-320234. doi: 10.1136/gutjnl-2019-320234.
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  54. DING L, Li Q, Chakrabarti J, Munoz A, et al
    MiR130b from Schlafen4(+) MDSCs stimulates epithelial proliferation and correlates with preneoplastic changes prior to gastric cancer.
    Gut. 2020 Jan 24. pii: gutjnl-2019-318817. doi: 10.1136/gutjnl-2019-318817.
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  55. ERAWIJANTARI PP, Mizutani S, Shiroma H, Shiba S, et al
    Influence of gastrectomy for gastric cancer treatment on faecal microbiome and metabolome profiles.
    Gut. 2020 Jan 16. pii: gutjnl-2019-319188. doi: 10.1136/gutjnl-2019-319188.
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  56. GUIMARAES P, Keller A, Fehlmann T, Lammert F, et al
    Deep-learning based detection of gastric precancerous conditions.
    Gut. 2020;69:4-6.
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  57. WANG R, Song S, Harada K, Ghazanfari Amlashi F, et al
    Multiplex profiling of peritoneal metastases from gastric adenocarcinoma identified novel targets and molecular subtypes that predict treatment response.
    Gut. 2020;69:18-31.
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    December 2019
  58. GUO Y, Zhang Y, Gerhard M, Gao JJ, et al
    Effect of Helicobacter pylori on gastrointestinal microbiota: a population-based study in Linqu, a high-risk area of gastric cancer.
    Gut. 2019 Dec 19. pii: gutjnl-2019-319696. doi: 10.1136/gutjnl-2019-319696.
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  59. COSTA L, Corre S, Michel V, Le Luel K, et al
    USF1 defect drives p53 degradation during Helicobacter pylori infection and accelerates gastric carcinogenesis.
    Gut. 2019 Dec 10. pii: gutjnl-2019-318640. doi: 10.1136/gutjnl-2019-318640.
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    October 2019
  60. JANSEN M, Banks M
    Early detection and risk stratification of gastric cancer are likely to be refined with biopsies targeted through high-resolution-enhanced imaging.
    Gut. 2019 Oct 14. pii: gutjnl-2019-319921. doi: 10.1136/gutjnl-2019-319921.
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  61. WANG Q, Chen C, Ding Q, Zhao Y, et al
    METTL3-mediated m(6)A modification of HDGF mRNA promotes gastric cancer progression and has prognostic significance.
    Gut. 2019 Oct 3. pii: gutjnl-2019-319639. doi: 10.1136/gutjnl-2019-319639.
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    September 2019
  62. BANKS M, Graham D, Jansen M, Gotoda T, et al
    British Society of Gastroenterology guidelines on the diagnosis and management of patients at risk of gastric adenocarcinoma.
    Gut. 2019;68:1545-1575.
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    May 2019
  63. DOORAKKERS E, Lagergren J, Engstrand L, Brusselaers N, et al
    Reply to: Helicobacter pylori eradication treatment and the risk of gastric adenocarcinoma in a western population.
    Gut. 2019 May 21. pii: gutjnl-2019-319000. doi: 10.1136/gutjnl-2019-319000.
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    January 2019
  64. LI T, Guo H, Li H, Jiang Y, et al
    MicroRNA-92a-1-5p increases CDX2 by targeting FOXD1 in bile acids-induced gastric intestinal metaplasia.
    Gut. 2019 Jan 11. pii: gutjnl-2017-315318. doi: 10.1136/gutjnl-2017-315318.
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